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Murthy Santosh B SB Department of Neurology, Baylor College of Medicine, 6501 Fannin, NB 302, Houston, TX 77030, - - 2014
Neurogenic stunned myocardium (NSM) after subarachnoid hemorrhage (SAH) is well known, but there is a paucity of data regarding its occurrence following acute stroke. The aim of this study is to investigate the clinical characteristics of NSM in acute non-hemorrhagic stroke. We performed an electronic literature search with Medline and ...
Velagapudi Poonam P Department of Cardiovascular Medicine, University of Missouri-Columbia, School of Medicine, Columbia, MO, - - 2014
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia and approximately 18-45% of AF patients have concomitant coronary artery disease (CAD). Several studies have demonstrated that oral anticoagulation is the mainstay of therapy for stroke prevention in AF. Similarly, antiplatelet therapy including aspirin and P2Y12 inhibitor is recommended in the ...
Alli Oluseun O The Division of Cardiovascular Diseases and Department of Internal Medicine, University of Alabama, Birmingham, AL, - - 2014
Left atrial appendage device occlusion for the preventions of systemic thromboembolism and stroke represents a major breakthrough in the field of cardiovascular disease. The wide prevalence of atrial fibrillation with devastating consequences of thromboembolic stroke as a result of thrombus arising from the left atrial appendage has led to the ...
Zafrir Barak B Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center and The Ruth and Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel - - 2014
Impaired cardiorespiratory fitness (CRF) is a potent risk factor for mortality in diabetes, and may modify the relation between adiposity and mortality. We evaluated the interaction between CRF and abdominal adiposity distribution with all-cause mortality, myocardial infarction or stroke in patients with diabetes. We studied 294 type 2 diabetics without ...
Zhang Changqing C From the Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China (C.Z., Yilong Wang, X. Zhao, L.L., C.W., Y.P., X. Zou, W.D., J.J., Y.P., Yongjun Wang); INI Stroke Network, OSF Healthcare System, University of Illinois College of Medicine, Peoria (D.W.); and Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China - - 2014
Single subcortical infarction (SSI) may be classified as proximal SSI (pSSI) or distal SSI (dSSI) according to its location within the middle cerebral artery territory. Few studies have examined the differences in clinical outcome between the 2. Our study investigated such differences in patients with pSSI or dSSI and examined ...
Boelman Cyrus C Division of Neurology, Hospital for Sick Children, Toronto, - - 2014
To assess the safety and efficacy of antithrombotic therapy (ATT) for secondary stroke prevention of childhood bacterial meningitis. A retrospective study of cases of stroke associated with bacterial meningitis in 2 pediatric hospitals during a period of 15 years. Patients were included in the study if between 28 days and 18 years of ...
Binsell-Gerdin Emil E Department of Public Health and Clinical Medicine, Östersund, Umeå University, Sweden. Electronic address: - - 2014
Hemorrhagic stroke is a rare but serious complication after an acute myocardial infarction (AMI). The aims of our study were to establish the incidence, time trends and predictors of risk for hemorrhagic stroke within 30days after an AMI in 1998-2008. We collected data from the Register of Information and Knowledge ...
Sharma Abhishek A Department of Medicine, Maimonides Medical Center, Brooklyn, NY. Electronic address: - - 2014
To investigate the relationship of body mass index (BMI) with total mortality, cardiovascular (CV) mortality, and myocardial infarction (MI) after coronary revascularization procedures (coronary artery bypass grafting [CABG] and percutaneous coronary intervention [PCI]). Systematic search of studies was conducted using PubMed, CINAHL, Cochran CENTRAL, Scopus, and the Web of Science ...
López-Cancio Elena E Department of Neurosciences, Germans Trias i Pujol University Hospital, Badalona, - - 2014
Background: There are limited data on the specific mechanisms of stroke in patients with intracranial atherosclerotic stenosis (ICAS). We undertook this study to describe infarct patterns and likely mechanisms of stroke in a large cohort of patients with ICAS, and to evaluate the relationship of these infarct patterns to angiographic ...
Sędkowska Agnieszka - - 2014
INTRODUCTION  Impaired glucose tolerance (IGT) has a negative impact on the outcome of patients with acute myocardial infarction (AMI). OBJECTIVES Based on the result of oral glucose tolerance test 560 patients with IGT were selected out of a single center registry of 2733 consecutive patients with AMI (395 men, 165 women). Sex ...
Thomassin Stefanie S SS From the Department of Family Medicine, Drexel University, Philadelphia, PA. - - 2014
Taste and smell disorders have multiple causes. We describe a patient in whom atrial fibrillation and subsequent embolic stroke was discovered because of complaints of decreased smell and taste. These deficits ultimately improved after treatment of the atrial fibrillation along with anticoagulation medication for stroke prevention.
Ungru Kathrin K Department of Mathematics and Computer Science, University of Münster, Münster, - - 2014
Multiple statistics show that heart diseases are one of the main causes of mortality in our highly developed societies today. These diseases lead to a change of the physiology of the heart, which gives useful information about characteristic and severity of the defect. A fast and reliable diagnosis is the ...
Kim Jinkwon J From the Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Gyeonggi-do, Korea (J.K.); Department of Neurology, Ewha Womans University, Seoul, Korea (T.-J.S.); and Departments of Neurology (J.K., E.H.K., K.J.L., D.S., H.S.N., Y.D.K., J.H.H.) and Biostatistics (H.S.L., C.M.N.), Yonsei University College of Medicine, Seoul, - - 2014
We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. We included 1091 consecutive patients with first-ever acute cerebral infarction who underwent baPWV measurements. Stroke subtypes were classified using the Trial ...
Zhu Wenbin W Department of Anesthesiology & Perioperative Medicine, Oregon Health & Science University, Portland, OR, 97239, - - 2014
RTL1000 is a partial human MHC molecule coupled to a human myelin peptide. We previously demonstrated that RTL1000 was protective against experimental ischemic stroke in HLA-DR2 transgenic (DR2-Tg) mice. Since thrombolysis with recombinant tissue plasminogen activator (t-PA) is a standard therapy for stroke, we determined if RTL1000 efficacy is altered ...
Violi Francesco F Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, - - 2014
An enhanced risk of cardiovascular mortality has been observed after pneumonia. Epidemiological studies have shown that respiratory tract infections are associated with an increased risk of thrombotic-related vascular disease such as myocardial infarction, ischemic stroke and venous thrombosis. Myocardial infarction and stroke have been detected essentially in the early phase ...
Haugaa Kristina H KH Department of Internal Medicine/Division of Cardiovascular Diseases, Mayo Clinic, Rochester, - - 2014
QT prolongation on ECG is a risk marker of ventricular arrhythmias and all-cause mortality. Left ventricular hypertrophy (LVH) on ECG is also associated with poor outcome. Patients satisfying ECG voltage criteria for LVH frequently show concomitant QT prolongation. To explore the impact of marked QT prolongation on all-cause mortality in ...
Giugliano Robert P RP From the Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (R.P.G., C.T.R., S.D.W., C.L., N.D., S.A.M., L.T.G., E.M.A., E.B.); Department of Neurology, Massachusetts General Hospital, Boston (N.S.R., S.S.); Biostatistics, Quintiles, Inc, Durham, NC (J.M.B.); and Daiichi Sankyo, Inc, Pharma Development, Edison, NJ (A.D., J.D., M.S., M.M.). - - 2014
The once-daily oral factor Xa inhibitor, edoxaban, is as effective as warfarin in preventing stroke and systemic embolism while decreasing bleeding in a phase III trial of patients with atrial fibrillation at moderate-high stroke risk. Limited data regarding cerebrovascular events with edoxaban were reported previously. We analyzed the subtypes of ...
Martínez-Rubio Antoni A Department of Cardiology, University Hospital of Sabadell (University Autònoma de Barcelona), Barcelona, Spain - - 2014
In the majority of patients with non-valvular atrial fibrillation (AF) anticoagulation is required to reduce the risk of stroke. Although vitamin K antagonists effectively reduce the risk of stroke, they have many disadvantages that limit their use. Rivaroxaban is a new once-daily oral anticoagulant that overcomes some of these limitations ...
Bauters Christophe C Centre Hospitalier Régional et Universitaire de Lille, Lille, France Inserm U744, Institut Pasteur de Lille, Université Lille Nord de France, Lille, France Faculté de Médecine de Lille, Lille, - - 2014
To assess the association of ß-blocker use with cardiovascular mortality in patients with stable coronary artery disease (CAD). We analysed the data of 4184 outpatients included in a prospective cohort study on stable CAD. Two groups were formed based on ß-blocker use at enrolment. Two propensity score analyses were performed ...
Bangalore Sripal S From the Division of Cardiology, New York University School of Medicine (S.B., F.F.); and Division of Cardiology, Virginia Commonwealth University, Richmond (B.T.). - - 2014
Coronary artery bypass graft surgery (CABG) compared with percutaneous coronary intervention (PCI) reduces mortality in patients with diabetes mellitus. However, prior trials compared CABG with balloon angioplasty or older generation stents, and it is not known if the gap between CABG and PCI can be reduced by newer generation drug-eluting ...
van Oeffelen A A M AA Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The - - 2014
To investigate differences in 28-day and 5-year mortality and 5-year readmission after a first hospitalisation for acute myocardial infarction (AMI) and congestive heart failure (CHF) between first generation ethnic minority groups (henceforth, migrants) and the ethnic Dutch population. Nationwide prospective cohorts of first hospitalised AMI (N=213 630) and CHF patients (N=189 069) ...
Lindberg Søren S Department of Cardiology P, Gentofte University Hospital, Copenhagen, Denmark - - 2014
Atrial natriuretic peptide (ANP) is released from the atria (on cleavage of proANP) in response to elevated intra-atrial pressure and wall stretch. Clinical data on proANP are still limited, mainly due to limitations in assaying the protein, which recently have been solved. ProANP is elevated in cardiovascular disease and predicts ...
Willey Joshua Z JZ Department of Neurology, Division of Stroke and Cerebrovascular Diseases. Electronic address: - - 2014
Cerebral infarction and hemorrhage are among the principal sources of morbidity and mortality associated with mechanical circulatory support. There has been particular concern with the recently reported increased rate of device thrombosis in continuous-flow left ventricular assist devices. The neurologic management of stroke among these patients has limited data to ...
Hart S S NHS - - 2014
Most modern Acute Stroke Services have a Local Guideline to indicate selection for Echocardiography. Nevertheless it is unknown who is selected and how the results influence Stroke patients' management. In addition, there is wide variation of investigation and treatments in clinical practice and amongst Local and National Guidelines. Echocardiography for ...
Keene Daniel D Imperial College - - 2014
Epidemiological studies have shown HDL to be a prognostic marker. We undertook a meta-analysis to assess the benefit on cardiovascular outcomes for those patients on pharmacological interventions aimed at increasing HDL. Niacin, fibrates and cholesteryl ester transfer protein inhibitors (CETP-I) were identified as agents that raise HDL levels. We conducted ...
Robinson Austin A AA Department of Internal Medicine, Yale School of Medicine, New Haven, - - 2014
Few prospective studies support the use of anticoagulation during the acute phase of ischemic stroke, though observational data suggest a role in certain populations. Depending on the mechanism of stroke, systemic anticoagulation may prevent recurrent cerebral infarction, but concomitantly carries a risk of hemorrhagic transformation. In this article, we describe ...
Kfoury Elias E Inova Fairfax Hospital, Virginia, USA - - 2014
Multiple studies have evaluated the effect of anesthesia type on carotid endarterectomy with inconsistent results. Our study compared 30-day postoperative myocardial infarction, stroke, and mortality between carotid endarterectomy under local or regional anesthesia and carotid endarterectomy under general anesthesia utilizing National Surgical Quality Improvement Program database. All patients listed in ...
Lau Kui Kai - - 2014
Patients with myocardial infarction are at risk of the development of atrial fibrillation (AF) and ischemic stroke. We sought to evaluate the prognostic performance of the CHADS2- and CHA₂DS₂-VASc scores in predicting new AF and/or ischemic stroke in post-ST segment elevation myocardial infarction (STEMI) patients. 607 consecutive post-STEMI patients with ...
Ozkul-Wermester Ozlem O Department of Neurology, Rouen University Hospital, Rouen, - - 2014
Background/Purpose: Perfusion computed tomography (CT) is capable of measuring the permeability surface product (PS). PS reflects the permeability of the blood-brain barrier, involved in the pathophysiology of hemorrhagic transformation (HT) of ischemic stroke. The aim of our study was to determine if an increased PS can predict HT. Methods: A ...
Sheth Sunil A SA Department of Neurology, University of California Los Angeles, Los Angeles, California, - - 2014
The ideal population of patients for endovascular therapy (ET) in acute ischemic stroke remains undefined. Recent ET trials have moved towards selecting patients with proximal middle cerebral artery (MCA) or internal carotid artery occlusions, which will likely leave a gap in our understanding of the treatment outcomes of M2 occlusions. ...
Kikkert Wouter J WJ Academic Medical Center-University of Amsterdam, Amsterdam, the - - 2014
This study sought to investigate the prognostic value of access site bleeding (ASB) and non-ASB for recurrent ischemic outcomes and mortality in patients with ST-segment elevation myocardial infarction (STEMI). The prognostic value of ASB-related complications after STEMI is subject to debate. The prognostic value of ASB and non-ASB for 1-year ...
Brown Devin L DL Stroke Program, The Cardiovascular Center - Stroke Program, 1500 E. Medical Center Drive - SPC#5855, Ann Arbor, MI 48109-5855, USA. Electronic address: - - 2014
Association between cerebral infarction site and poststroke sleep-disordered breathing (SDB) has important implications for SDB screening and the pathophysiology of poststroke SDB. Within a large, population-based study, we assessed whether brainstem infarction location is associated with SDB presence and severity. Cross-sectional study was conducted on ischemic stroke patients in the ...
Singh Vikas V Cardiovascular Division, and the Elaine and Sydney Sussman Cardiac Catheterization Laboratory, University of Miami Hospital, Miller School of Medicine, 1400 N.W. 12th Avenue, Suite 1179, Miami, FL, 33136, - - 2014
The estimated annual incidence of new and recurrent myocardial infarction (MI) in the U.S. is 715,000 events. Primary percutaneous coronary intervention (PCI) is the reperfusion strategy of choice in most patients with acute ST-elevation myocardial infarction (STEMI). Recent advances in percutaneous techniques and devices, including manual aspiration catheters and newer ...
Hussain Sarah K SK The University of Virginia, Charlottesville, VA, USA, - - 2014
Atrial fibrillation (AF) is the most commonly encountered clinical arrhythmia, and stroke prevention remains an integral part of management of AF. Long-term therapy with oral anticoagulants, though effective, has many limitations, and these limitations have encouraged the search for device-based alternatives. In patients with non-valvular AF, approximately 90 % of thrombi ...
Mazya Michael V MV From the Department of Neurology, Karolinska University Hospital (M.V.M., N.A., N.W.) and Department of Clinical Neuroscience (M.V.M., N.A., N.W.), Karolinska Institutet, Stockholm, Sweden; Stroke Research Group, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, Tyne and Wear, United Kingdom (G.A.F.); Department of Neurology, University of Leipzig, Leipzig, Germany (C.H.); International Clinical Research Center, Neurology Department, St Anne's Hospital, Brno, Czech Republic (R.M.); and Stroke Unit, Centro Hospitalar Lisboa Central, Lisbon, Portugal - - 2014
Intracerebral hemorrhage after treatment with intravenous recombinant tissue-type plasminogen activator for ischemic stroke can occur in local relation to the infarct, as well as in brain areas remote from infarcted tissue. We aimed to describe risk factors, 3-month mortality, and functional outcome in patients with the poorly understood complication of ...
Tu H T HT University Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia; Department of Neurology, The University of Melbourne, Melbourne, Victoria, - - 2014
This pilot study in a prospective cohort of 20 cryptogenic stroke patients showed that a significant proportion has paroxysmal atrial fibrillation undetected by 24-h Holter monitoring. However, longer monitoring with 28-day Holter was poorly tolerated and still insufficiently sensitive for paroxysmal atrial fibrillation detection. Further studies are urgently needed to ...
Aydin E E Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey. - - 2014
There is controversy over the best approach for patients with concomitant carotid and coronary artery disease. In this study, we report on our experience with simultaneous carotid endarterectomy (CEA) and coronary artery bypass graft (CABG) surgery in our clinic in the light of data in the literature. Between January 1996 ...
Scordo Kristine Anne KA Kristine Anne Scordo is a professor and director of the AG-ACNP Program at Wright State University, Dayton, Ohio. Kim Anne Pickett is a family nurse practitioner at Medical Group of the Carolinas (endocrinology), Spartanburg, - - 2014
: Hypertension, if not appropriately treated, can lead to stroke, kidney failure, myocardial infarction, and death. Substantial evidence from multiple randomized clinical trials demonstrates the benefit of antihypertensive therapy. Healthcare providers seek scientific evidence by which to base treatments. The purpose of this article is to discuss current hypertension guidelines.
Rosanio Salvatore S Department of Internal Medicine, Division of Cardiology, University of North Texas Health Science Center, Fort Worth, TX, United States. Electronic address: - - 2014
This systematic review aims to provide an update on pharmacology, efficacy and safety of the newer oral direct thrombin and factor Xa inhibitors, which have emerged for the first time in ~60years as cogent alternatives to warfarin for stroke prophylaxis in non-valvular atrial fibrillation. We also discuss on four of ...
Guidoni S V SV Department of Neuroscience, Mental Health and Sensory Systems, NESMOS, 'Sapienza' University of Rome, Rome, Italy, - - 2014
Tako-tsubo cardiomyopathy (TTC), also known as "stress induced cardiomyopathy", is an acute cardiac condition characterized by transient myocardial dysfunction associated with a peculiar pattern of reversibile left ventricular ballooning that mimics myocardial infarction, but with normal coronary arteries. Tako-tsubo cardiomyopathy typically occurs in postmenopausal women and it is often triggered ...
Nielsen Susanne S Susanne Nielsen, MSc PhD Student, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden. Kristin Falk, PhD Senior Lecturer, Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden. Anna Gyberg, MSc Faculty of Education, Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden. Sylvia Määttä, PhDAdjunct Senior Lecturer, Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden. Lena Björck, PhD Senior Lecturer, Department of Molecular and Clinical Medicine, and Institute of Health and Care Sciences, and Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, - - 2014
Previous studies have shown that people hesitate to seek medical attention when experiencing the initial symptoms of acute myocardial infarction (AMI), but the reasons why and the events underpinning the decision-making process are unclear. The aim of this study was to describe the actions and experiences involved in the process ...
Tütüncü Serdar S Departments of Neurology (S.T., J.F.S., M.E., C.H.N.). Electronic address: - - 2014
Stroke with tandem occlusion within the anterior circulation presents a lower probability of recanalization and good clinical outcome after intravenous (IV) thrombolysis than stroke with single occlusion. The present study describes the impact of endovascular procedures (EPs) compared with IV thrombolysis alone on recanalization and clinical outcome. Thirty patients with ...
English Joey D JD Departments of Radiology and Biomedical Imaging, San Francisco, California, - - 2014
The rabbit small clot embolic model for large vessel occlusion (LVO) is well established, yet has limitations. Blind introduction of autologous thrombus often fails to completely occlude a target vessel and, when successful, the precise timing of occlusion and revascularization is difficult to control. Studies of cellular biology and neuroimaging ...
Saito Shin S Hirosaki Stroke and Rehabilitation Center, Hirosaki, Japan. Electronic address: - - 2014
We report a case of a nonvalvular atrial fibrillation (NVAF) patient with acute cardioembolic stroke in whom rivaroxaban, an oral direct factor Xa inhibitor, reduced a smoke-like echo in the left atrium and resolved a thrombus in the left atrial appendage. A 71-year-old man was admitted because of the sudden ...
Ntaios G G Department of Medicine, Medical School, University of Thessaly, Larissa, - - 2014
There is no strong evidence that all ischaemic stroke types are associated with high cardiovascular risk. Our aim was to investigate whether all ischaemic stroke types are associated with high cardiovascular risk. All consecutive patients with ischaemic stroke registered in the Athens Stroke Registry between 1 January 1993 and 31 ...
Oygarden H H Department of Neurology, Haukeland University Hospital, Bergen, Norway; Institute of Clinical Medicine, University of Bergen, Bergen, - - 2014
There is increasing knowledge about an association between migraine and ischaemic stroke. Cortical spreading depression (CSD) is the probable biological substrate of migrainous aura. To investigate the influence of CSD on the apparent stroke - migraine association, we hypothesized that magnetic resonance (MR) diffusion weighted images of acute ischaemic stroke ...
Opthof T T Department of Clinical and Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, Meibergdreef 9, Room K2-111, 1105 AZ, Amsterdam, the Netherlands, - - 2014
The impact factor of the Netherlands Heart Journal was stable at about 1.4 between 2009 and 2012. In 2013 it will break through the 2.0 barrier for the first time.
Kajermo Ulf U From the Skaraborgs Hospital, Skövde, Sweden (U.K.); Östersunds Hospital, Östersund, Sweden (A.U., A.M.); Karolinska Institutet, Solna, Sweden (T.J.); and Umeå University, Umeå, Sweden - - 2014
Ischemic stroke is a known complication of acute myocardial infarction (AMI). Treatment of AMI has undergone great changes in recent years. We aimed to investigate whether changes in treatment corresponded to a lower incidence of ischemic stroke and which factors predicted ischemic stroke after AMI. Data were taken from the ...
Kim Anthony S - - 2014
The potential for cardioembolic stroke has important implications for clinical management. This review describes the diagnostic workup and management options for this key stroke subtype. The suspicion for a cardioembolic source for stroke is raised with a large vessel occlusion or when strokes occur in multiple vascular territories. Diagnostic workup ...
de Figueiredo Marcelo Marinho MM Departamento de Neurologia e Neurocirurgia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, - - 2014
Atrial fibrillation is a common arrhythmia that increases the risk of stroke by four- to five-fold. We aimed to establish a profile of patients with atrial fibrillation from a population of patients admitted with acute ischemic stroke or transient ischemic attack using clinical and echocardiographic findings. We evaluated patients consecutively ...
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