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Kaya A A Department of Cardiology, Dr Siyami Ersek Cardiovascular Surgery Hospital, Istanbul, - - 2014
Acute spinal cord ischemia syndrome (ASCIS) due to coronary invasive intervention is rarely seen. In this case report we wish to highlight the mortality and morbidity of this entity. Case report. A 60-year-old woman, diagnosed with acute myocardial infarction, presented with paresthesia and paraparesis of her legs after coronary invasive ...
Schreiber Roberto R Department of Internal Medicine, University of Campinas, Campinas, - - 2014
Subjects with spinal cord injury (SCI) exhibit impaired left ventricular (LV) diastolic function, which has been reported to be attenuated by regular physical activity. This study investigated the relationship between circulating matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) and echocardiographic parameters in SCI subjects and the role of ...
Mustafa Khader N KN Rheumatology Unit, Department of Internal Medicine, Jordan University Hospital, The University of Jordan, Queen Rania St, P.O. Box 13046, Amman, 11942, Jordan, - - 2014
Spinal cord infarction is extremely rare in patients with giant cell arteritis (GCA). There are only four case reports in the literature. We describe a 65-year-old man who presented with sudden paraplegia and back pain of 4-days duration with sensory loss below the umbilicus and bilateral scalp necrosis. Magnetic resonance ...
Bansal Seema S Children's National Medical Center, Washington, District of Columbia - - 2014
Spinal cord infarction is extremely rare in children, and, similar to cerebrovascular infarcts, the pathogenesis is different from adults. Spinal cord infarcts are most commonly reported in adults in the context of aortic surgery; in children, the etiology is frequently unknown. Fibrocartilaginous embolization is a potential cause of spinal cord ...
Walega David D Division of Pain Medicine, Department of Anesthesiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, - - 2014
To observe the effect of thoracic spinal cord stimulation with dual octipolar epidural electrodes on episodes of ventricular tachycardia and ventricular fibrillation in a patient with nonischemic familial cardiomyopathy and severe electrical storm refractory to conventional medical treatment. Following implantation of temporary bilateral octipolar thoracic epidural electrodes and constant low-grade ...
Tanaka Hiroshi H Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan - - 2014
We reviewed magnetic resonance (MR) findings of the spinal cord in patients who had a spinal cord injury after descending and thoracoabdominal aortic repair, to speculate the specific cause of the injury. Between 2000 and 2012, 746 patients underwent descending or thoracoabdominal aortic surgery: 480 received an open repair with ...
Chen Hui H Department of Anesthesiology, First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian 350005, P.R. - - 2014
Phosphocreatine (PCr) mobilizes high-energy phosphates in cardiac muscles, which is potentially useful as a cardioprotective agent in patients with spinal cord injury (SCI). The cardioprotective effects of PCr on myocardial cell ultrastructure and calcium-sensing receptor (CaSR) expression following high-level spinal cord injury (SCI) were investigated. Healthy adult male Sprague-Dawley (SD) ...
Spencer Sandra P SP From the *Department of Emergency Medicine, Nationwide Children's Hospital, Columbus, OH; and †Department of Emergency Medicine, Willamette Valley Medical Center, McMinnville, - - 2014
Nontraumatic spinal cord infarction is especially rare in children. Although diagnosis is easily made with magnetic resonance imaging, the typical presenting signs and symptoms and etiology remain elusive. Evidence-based treatment courses are not available. We assess a series of 3 unique patients with nontraumatic spinal cord infarction who presented to ...
Mendonça Marcelo M Neurology Department, Hospital Egas Moniz - Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal ; CEDOC, Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Lisbon, - - 2014
Spinal cord infarction (SCI) is an uncommon but important cause of acute myelopathy. Nevertheless, contrary to cerebral stroke, the discussion about paradoxical embolism as a cause of cryptogenic SCI remains dubious. We describe the case of a 24-year-old woman who developed sudden-onset back pain followed by upper limb paralysis. T2-weighted ...
Lopshire John C JC Krannert Institute of Cardiology, Indiana University School of Medicine, 1800 N. Capitol Avenue, Suite E310, Indianapolis, IN, 46202, USA, - - 2014
Spinal cord stimulation with implantable devices has been used worldwide for decades to treat regional pain conditions and cardiac angina refractory to conventional therapies. Preclinical studies with spinal cord stimulation in experimental animal models of heart disease have described interesting effects on cardiac and autonomic nervous system physiology. In canine ...
Patel Sonali S Department of Accident and Emergency, Milton Keynes General Hospital, Milton Keynes, - - 2014
Spinal cord infarction is rare and represents a diagnostic challenge for many physicians. There are few reported cases worldwide with a prevalence of 1.2% of all strokes. Circulation to the spinal cord is supplied by a rich anastomosis. The anterior spinal artery supplies the anterior two thirds of the spinal ...
Gupta Kamal K Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru 560069, Karnataka, - - 2013
Thrombolytic therapy directed to the achievement of early reperfusion in cases with acute ST elevation myocardial infarction can have significant complications which can be due to bleeding or in the form of allergic reactions. Sometimes these complications can cause mortality or significant and incapacitating morbidity which may at times surpass ...
Lanza Gaetano A - - 2013
Microvascular angina (MVA) is defined as angina pectoris caused by abnormalities of small coronary arteries. In its most typical presentation, MVA is characterized by angina attacks mainly caused by effort, evidence of myocardial ischemia on non-invasive stress tests, but normal coronary arteries at angiography. Patients with stable MVA have excellent ...
Diehn Felix E - - 2013
Two valuable confirmatory MRI findings of acute spinal cord infarct are highlighted and discussed: concomitant vertebral body infarct and ventral cauda equina nerve root enhancement.
Lee Joon-Ho - - 2013
Bradycardia may occur during spinal anesthesia with atropine commonly used as a treatment. A 44-year-old female with no known history of any underlying diseases, developed a coronary spasm following ventricular tachycardia when 0.5 mg of atropine was injected intravenously to treat bradycardia during spinal anesthesia. The imbalance caused by atropine ...
Hsu Chia-Yu - - 2013
OBJECTIVE: Spinal cord infarction (SCI) is a rare complication of vertebral artery dissection (VAD). Its clinical features and outcomes have not yet been well documented. METHODS: In addition to reporting a case with bilateral SCI caused by left VAD, we performed a systematic review of the literature conducted through a ...
Kumagai Naoto - - 2013
A 71-year-old man suddenly collapsed and went into cardiopulmonary arrest. The cardiopulmonary resuscitation attempt succeeded in restoration of spontaneous circulation. The initial 12-lead electrocardiogram showed inferior acute myocardial infarction (AMI). The patient was initially diagnosed as having cardiogenic shock associated with inferior AMI. In spite of early coronary revascularisation, bradycardia ...
Edwards April A Departments of Pediatrics and Internal Medicine, Division of Hematology and Oncology, University of North Carolina School of Medicine, 170 Manning Drive 1185A, Physician Office Building CB#7236, Chapel Hill, NC 27599-7236, USA. - - 2013
Vasculopathy of the large vessels commonly occurs in sickle cell disease, and as a result cerebral infarction is a well characterized complication of this condition. However, spinal infarction appears to be rare. Spinal infarct is infrequent in the non-sickle cell population as well, and accounts for only about 1 percent ...
Kalb Samuel - - 2012
OBJECTIVE: Spinal cord infarction is a rare cause of neurologic deterioration after cervical spine decompressive surgery. Proposed causes of ischemic events include intraoperative or postoperative hypotension, or decreased venous return in conjunction with elevated vertebral venous pressures, which reduces arterial perfusion when patients undergo surgery in the prone position. Neuro-imaging ...
Nakae Yoshiharu - - 2012
Cervical angina is defined as chest pain resembling true cardiac angina but originating from disorders of the cervical spine. Cervical angina is caused by cervical spondylosis in most cases. A 66-year-old man presented with bilateral arm palsy after chest pain resembling angina pectoris. Neurological examination revealed motor and sensory disturbances ...
Singh Pm - - 2012
Intraoperative myocardial ischemia is attributed to decreased myocardial oxygen supply. We present an unusual case of recurrent, symptomless inferior wall ischemia in an apparently healthy male with no history of coronary artery disease after a spinal block. The recurring episodes were linked to tachycardia and presented with significant ST depression ...
Gorelik N - - 2012
A 25-year-old woman developed a spinal cord infarction leading to quadriplegia and respiratory insufficiency after consuming cocaine and vodka for several days. Within five months, she regained full motor and respiratory function. A literature review revealed 11 cases of cocaine-induced spinal cord infarction. A complete recovery from quadriplegia and respiratory ...
Aarsaether Erling - - 2012
The extension and the transmurality of the myocardial infarction are of high predictive value for clinical outcome. The aim of the study was to characterize the ability of longitudinal, circumferential and radial strain measured by 2-dimensional speckle tracking echocardiography (2D-STE) to predict the extent of necrosis in myocardial segments following ...
Beauchamp Gillian A GA Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, - - 2012
Introduction. Neurogenic stunned myocardium (NSM) is a reversible cardiomyopathy resulting in transient left ventricular apical ballooning presumed to result from catecholamine surge occurring under physiologic stress. Acute spinal cord ischemia is a rare ischemic vascular lesion. We report a case of neurogenic stunned myocardium occurring in the setting of acute ...
Kardassis Dimitris - - 2012
Alterations in left ventricular mass and geometry vary along with the degree of obesity, but mechanisms underlying such covariation are not clear. In a case-control study, we examined how body composition and fat distribution relate to left ventricular structure and examine how sustained weight loss affects left ventricular mass and ...
Robb J Daniel - - 2011
Ischemic mitral regurgitation results from annular dilatation, leaflet tethering and leaflet flattening. Undersized annuloplasty corrects annular dilatation but worsens leaflet tethering and flattening. This exacerbation of abnormal leaflet geometry may contribute to poor repair results for ischemic mitral regurgitation (IMR). Using a sheep model of IMR, we hypothesized that posterior ...
Miyasaka Yoko - - 2011
BACKGROUND: Left atrial (LA) enlargement has been acknowledged as a significant predictor of cardiovascular morbidity and mortality. METHODS: To evaluate the accuracy of two-dimensional and three-dimensional echocardiography for determining LA volume, LA volume measurements by echocardiography were compared with those measured by 64-slice multidetector computed tomography (MDCT) as a reference ...
Kato Yoshiaki - - 2011
An 11-year-old girl presented with focal atrial tachycardia (AT) originating from inside the inferior vena cava (IVC). Sustained AT appeared 10 years after surgical repair of the congenital heart defects. Focal AT was successfully eliminated with radiofrequency application at the earliest activation site, about 8 mm below the IVC right atrium junction. ...
Gonzalez Manuel A - - 2011
Background: Prehospital 12-lead electrocardiogram (ECG) reduces the time to reperfusion in acute ST-segment elevation myocardial infarction (STEMI). However, the reliability of using cellular video-phone (VP) assisted interpretation of ECG is unknown. Methods: We studied the interphysician reliability in interpreting the ECG assisted with VP compared to print ECG interpretation. Twenty-seven ...
Pedraza Salvador - - 2011
BACKGROUND AND PURPOSE: Infarct volume is used as a surrogate outcome measure in clinical trials of therapies for acute ischemic stroke. ABC/2 is a fast volumetric method, but its accuracy remains to be determined. We aimed to study the accuracy and reproducibility of ABC/2 in determining acute infarct volume with ...
Aldous Sally - - 2011
Aims:  To investigate the safety and efficacy of everolimus-eluting stents (EES) in a real world population, including those with high-risk characteristics and complex lesions. Methods:  In this report, we analyze 2-year outcomes in 500 consecutive unselected patients treated with EES between April 2007 and March 2008. All patients were followed ...
Weiss Eric H EH Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, - - 2011
Electric alternans is a pattern of variation in the shape of ECG waveform that occurs every other beat. In humans, alternation in ventricular repolarization, known as repolarization alternans (RA), has been associated with increased vulnerability to ventricular tachycardia/fibrillation and sudden cardiac death. This study investigates the spatio-temporal variability of intracardiac ...
Benoist David D Institute of Membrane and Systems Biology, Garstang Bldg., Univ. of Leeds, Leeds LS29JT, - - 2011
Mechanisms associated with right ventricular (RV) hypertension and arrhythmias are less understood than those in the left ventricle (LV). The aim of our study was to investigate whether and by what mechanisms a proarrhythmic substrate exists in a rat model of RV hypertension and hypertrophy. Rats were injected with monocrotaline ...
Shen Chwan-Li - - 2011
OBJECTIVE: Green tea proposes anti-inflammatory properties which may attenuate chronic inflammation-induced fibrosis of vessels. This study evaluated whether green tea polyphenols (GTP) can avert fibrosis or vascular disruption along with mechanisms in rats with chronic inflammation. TREATMENTS: Forty 3-month-old female rats were assigned to a 2 (placebo vs. lipopolysaccharide, administration) × 2 ...
Ito Hiroki - - 2011
Aims: Previous risk models predicting in-hospital major adverse cardiac or cerebrovascular events (MACCE) after percutaneous coronary interventions (PCI) may underestimate actual short-term post-procedure complications due to the trend toward early discharge of patients. Methods and results: Using a subset (N=10,679) from the STENT Group registry, a logistic regression model was ...
Fernandes Daniela Ribeiro Aleixo DR Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil Fleury Group, São Paulo, - - 2011
Real time myocardial contrast echocardiography (RTMCE) is an emerging imaging modality for assessing myocardial perfusion that allows for noninvasive quantification of regional myocardial blood flow (MBF). We sought to assess the value of qualitative analysis of myocardial perfusion and quantitative assessment of myocardial blood flow (MBF) by RTMCE for predicting ...
Gmeiner Matthias - - 2011
BACKGROUND: Transplant of skeletal myoblasts is an attractive alternative to repair irreversibly damaged myocardium in ischemic heart failure. We investigated whether transplant of myoblasts overexpressing placental growth factor would stimulate angiogenesis and enhance myoblast survival in a rat heart failure model. METHODS: Three weeks after myocardial infarction, Sprague-Dawley rats in ...
Hiesinger William - - 2011
This study evaluates a therapy for infarct modulation and acute myocardial rescue and utilizes a novel technique to measure local myocardial oxygenation in vivo. Bone marrow-derived endothelial progenitor cells (EPCs) were targeted to the heart with peri-infarct intramyocardial injection of the potent EPC chemokine stromal cell-derived factor 1α (SDF). Myocardial ...
Pandis Dimosthenis - - 2011
OBJECTIVES: The aim of the present study was the assessment of left ventricular (LV) remodeling during the surgical management of degenerative mitral valve regurgitation (DMR) with the application of 2 emerging imaging modalities: real-time 3-dimensional echocardiography (3DE) and speckle tracking. METHODS: A total of 40 patients with DMR were prospectively ...
Garita Barbara B Department of Pediatrics, The Children’s Research Institute, University of South Florida and All Children’s Hospital, St. Petersburg, USA. - - 2011
Analyses of form-function relationships during heart looping are directly related to technological advances. Recent advances in four-dimensional optical coherence tomography (OCT) permit observations of cardiac dynamics at high-speed acquisition rates and high resolution. Real-time observation of the avian stage 13 looping heart reveals that interactions between the endocardial and myocardial ...
Barletta Giuseppe - - 2011
OBJECTIVE: Coronary vasodilation and coronary steal are the basis for routine use of dipyridamole in stress echocardiography for non-invasive assessment of coronary artery disease (CAD). This study investigates dipyridamole effects on cardiac (regional function, synchronicity and contractility) and systemic (ventricular arterial coupling) haemodynamics during real-time three-dimensional (RT3D) stress echocardiography in ...
Ayala-Lugo Ana - - 2011
The aim of this study was to investigate the effect of aging and timing of left ventricular ischemic injury on the availability and functionality of stem cells. We studied young and aged male inbred Lewis rats that were used as donors of bone marrow mononuclear cells (BM-MNCs), divided in four ...
Kobr Jiri - - 2011
The aim of this study was to verify the benefits and limitations of repeated bedside echocardiographic examinations in children during mechanical ventilation. For the purposes of this study, we selected the data of over a time period from 2006 to 2010. A total of 235 children, average age 3.21 (SD ...
Bai Wenjuan - - 2011
We report a case of a 52-year-old patient with dilated cardiomyopathy who presented with worsening heart failure. Two-dimensional transthoracic echocardiography and real-time three dimensional transthoracic echocardiography showed severe dilated cardiac chambers, impaired ejection fraction and a mobile right atrial thrombus 2.6 × 1.0 cm in size, traversing the right atrial ...
Bansal Ramesh C - - 2011
We report a case of a 63-year-old woman who presented with infective endocarditis and developed a pseudoaneurysm (PA) of the left ventricle presumably as a result of an embolic infarct. The diagnosis was made by typical features of PA on tranesophageal echocardiography and color Doppler studies. In addition, three-dimensional transesophageal ...
Huang Xi-Ping - - 2010
Cardiac cell therapy for older patients who experience a myocardial infarction may require highly regenerative cells from young, healthy (allogeneic) donors. Bone marrow mesenchymal stem cells (MSCs) are currently under clinical investigation because they can induce cardiac repair and may also be immunoprivileged (suitable for allogeneic applications). However, it is ...
Wetsch W A - - 2010
Sudden cardiac death is a leading cause of death in Europe. In the vast majority, myocardial infarction or pulmonary embolism is the underlying cause. Lethality is still high, especially if the arrest occurs out of hospital. For these two severe conditions, thrombolysis has proven to be an established therapy. Coronary ...
Pérez-Berbel Patricio - - 2011
Rescue angioplasty (RA) has demonstrated its efficacy for the treatment of failed thrombolysis after acute myocardial infarction (AMI). We analyzed clinical, angiographic, and procedural characteristics, and prognosis at 30 days of prospective cohort of unselected patients admitted for RA. From August 2004 to August 2009, 361 patients were included in ...
Karia Vijay R - - 2010
This report describes the case of a 29-day-old infant with Kawasaki's disease who presented in extremis with multiple coronary aneurysms and coronary thromboses, myocardial ischemia, and congestive heart failure. The infant successfully underwent emergent coronary thrombolysis with tissue plasminogen activator.
Matijević Vesna - - 2011
We present the case of a 41-year-old man with sudden development of left hemiparesis due to infarction of the right middle cerebral artery that was successfully treated with intravenous (IV) thrombolysis with alteplase. Transthoracic echocardiography showed a small mass in the left ventricle. The patient underwent surgical resection, and histological ...
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