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Nagele Peter - - 2011
Perioperative myocardial infarction is a common and potentially fatal complication after noncardiac surgery, particular among patients with cardiovascular risk factors. β-blockers have been considered a mainstay in prevention and treatment of perioperative myocardial infarction, yet recent evidence suggests that β-blockers may have an unfavorable risk profile in this setting, and ...
Ungerer Jacobus P J - - 2011
BACKGROUND:Data to standardize and harmonize the differences between cardiac troponin assays are needed to support their universal status in diagnosis of myocardial infarction. We characterized the variation between methods, the comparability of the 99th-percentile cutoff thresholds, and the occurrence of outliers in 4 cardiac troponin assays.METHODS:Cardiac troponin was measured in ...
Matyal Robina - - 2011
OBJECTIVES: To investigate the effects of acute elevation in afterload on global (systolic and diastolic) myocardial function by performing serial intraoperative transesophageal echocardiograms during and after cross-clamp application on patients undergoing elective abdominal aortic aneurysm (AAA) surgery. DESIGN: A prospective observational study. SETTING: A tertiary care university hospital. PARTICIPANTS: Patients ...
Perrault Louis P LP Department of Surgery, Montreal Heart Institute, University of Montréal, Montréal, Québec, - - 2012
Ischemic mitral regurgitation, a complication of myocardial infarction and coronary artery disease more generally, is associated with a high mortality rate and is estimated to affect 2.8 million Americans. With 1-year mortality rates as high as 40%, recent practice guidelines of professional societies recommend repair or replacement, but there remains ...
Phan T D - - 2011
This study compared the cardiac output responses to haemodynamic interventions as measured by three minimally invasive monitors (Oesophageal Doppler Monitor the VigileoFlotrac and the LiDCOrapid) to the responses measured concurrently using thermodilution, in cardiac surgical patients. The study also assessed the precision and bias of these monitors in relation to ...
Jones W Schuyler - - 2011
Although variation in use of invasive coronary procedures has been shown, the relationship between invasive diagnostic cardiac catheterization (Cath) and subsequent revascularization with percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) is not known. We evaluated the temporal trends and variation in invasive Cath, PCI, and CABG across ...
Ho Siew Yen - - 2011
The anatomy of the left atrium is reviewed with relevance to various interventional transcatheter procedures requiring manoeuvres within or passage through the left atrium. The component parts of the atrium-the atrial body with a vestibule, appendage, venous component, and the atrial septum-are described with emphasis on their spatial relationships to ...
Swenson Darrell J - - 2011
The electrocardiogram (ECG) is ubiquitously employed as a diagnostic and monitoring tool for patients experiencing cardiac distress and/or disease. It is widely known that changes in heart position resulting from, for example, posture of the patient (sitting, standing, lying) and respiration significantly affect the body-surface potentials; however, few studies have ...
Chen Chun-An - - 2011
Enzyme replacement therapy (ERT) for infantile-onset Pompe disease effectively reduces the left ventricular (LV) mass. This study sought to explore detailed process of LV reverse remodeling after ERT with the use of tissue Doppler and stain rate imaging. Nine infants and children with Pompe cardiomyopathy undergoing ERT for ≥1 year, ...
Gayat Etienne - - 2011
Most techniques previously used to assess left ventricular (LV) elastance (E(es)) and ventricular-arterial coupling (C(LV-A)) relied on invasive measurements and data acquisition over a wide range of loading conditions. Our goals were to: (1) assess the feasibility of noninvasive assessment of E(es) and C(LV-A) using real-time three-dimensional echocardiography (RT3DE) and ...
Christensen Jared D - - 2011
The purpose of this article is to assess whether iopamidol-370 provides superior vascular contrast of the coronaries and depiction of anatomic detail without affecting heart rate and beat-to-beat variability during coronary dual-source MDCT compared with iodixanol-320. In this prospective trial, coronary CT angiography was performed on 60 adult patients using ...
Zerbe Philipp - - 2011
Objective-To noninvasively evaluate physiologic postprandial adaptations of the heart in snakes. Animals-6 juvenile Paraguay anacondas (Eunectes notaeus). Procedures-The heart of each anaconda was echocardiographically evaluated after food was withheld for 28 days as well as 3 and 10 days after feeding. Physical measurements included body length, weight, and circumference at ...
Rolfes Christopher D - - 2011
Atrial fibrillation (AF) causes a continuum of atrial anatomical remodeling. Using a library of perfusion-fixed human hearts, specimens with AF were compared to controls. During this preliminary assessment study, direct measurements were taken of atrial volume, pulmonary vein (PV) circumference, and left atrial (LA) wall thicknesses. Hearts with AF typically ...
Katti Karuna - - 2011
Clinical cardiac procedures such as electrophysiology studies, catheter ablation of arrhythmias, retrograde cardioplegia delivery, cardiac resynchronization therapy and, more recently, percutaneous mitral annuloplasty, involve cannulation of the coronary sinus (CS). The presence of a membrane closing the orifice of the CS may cause difficulties during these interventions. Thus, detailed knowledge ...
Ahmad Talha J - - 2011
This paper discusses the effect of atrioventricular conduction time (AVCT) on the short-term Heart Rate Variability (HRV) by computing HRV parameters using intervals between the onsets of successive P waves (PP time series) for three groups: normal, arrhythmia and sudden cardiac death (SCD) patients. A very precise wavelet transform based ...
Eslami Abouzar - - 2011
In this paper we propose a new method for shape guided segmentation of cardiac boundaries based on manifold learning of the shapes represented by the phase field approximation of the Mumford-Shah functional. A novel distance is defined to measure the similarity of shapes without requiring deformable registration. Cardiac motion is ...
Ando Makoto - - 2011
BACKGROUND: Presently, there are wide variations in cardiac anatomies requiring single ventricular palliation and these variations may have an impact on the incidence of atrioventricular valve regurgitation. METHODS: In all, 363 patients underwent single ventricular palliation (1978 to 2008). Hearts were first classified into single right ventricle (156), single left ...
Chan Paul S PS Saint Luke's Mid America Heart and Vascular Institute, 4401 Wornall Rd, Fifth Floor, Kansas City, MO 64111, USA. - - 2011
Despite the widespread use of percutaneous coronary intervention (PCI), the appropriateness of these procedures in contemporary practice is unknown. To assess the appropriateness of PCI in the United States. Multicenter, prospective study of patients within the National Cardiovascular Data Registry undergoing PCI between July 1, 2009, and September 30, 2010, ...
Iqbal Toqueer - - 2011
Coronary artery diseases encompass a spectrum of disorders ranging from angina to fatal myocardial infarctions with the main underlying pathology being identified as atherosclerosis. The level of inflammatory markers, C-reactive protein and fibrinogen was determined in hundred patients with established coronary artery disease and correlated with lipid profile which included ...
Lloyd Christopher W - - 2011
Myocardial tissue characterization represents an extension of currently available echocardiographic imaging. The systematic variation of backscattered energy during the cardiac cycle (the "cyclic variation" of backscatter) has been employed to characterize cardiac function in a wide range of investigations. However, the mechanisms responsible for observed cyclic variation remain incompletely understood. ...
Karabag Turgut - - 2011
Background: Our aim was to investigate whether diastolic functions, myocardial velocities and pulmonary vein flow show diurnal variation within a 24-hour day. Method and Results: Fourty-four healthy subjects with no history of cardiovascular or systemic diseases (32 males, 12 females; mean age 34.7 ± 8.7 years, mean BMI: 25.5 ± ...
Kilbourne Barbara J - - 2011
: Coronary heart disease often presents with ST segment elevation acute myocardial infarction (STEMI). The American College of Cardiology/American Heart Association guidelines stress prompt reperfusion for STEMI. Examining geographic variations in treatment with PPCI (percutaneous primary coronary intervention) and CABG (coronary artery bypass graft) among metropolitan, micropolitan and non-micropolitan rural ...
Koplay Mustafa - - 2011
PURPOSE: The left atrial appendage (LAA) is usually known as a long, tubular, hooked structure derived from the left atrium. However, it varies widely in terms of anatomical shape. In this study, anatomical shape variations of the LAA were investigated and classified in vivo in a large group of patients ...
Becker Cristoph R - - 2011
OBJECTIVES:: To compare a contrast agent with high iodine concentration with an iso-osmolar contrast agent for coronary dual-source computed tomography angiography (DS-CTA), and to assess whether the contrast agent characteristics may affect the diagnostic quality of coronary DS-CTA. MATERIALS AND METHODS:: Patients were randomized to receive either 80 mL of ...
Goldfarb James W - - 2011
To evaluate the dependence of CINE-balanced steady-state free precession (bSSFP) image intensities on spatial location, cardiac phase, and disease state. Eight subjects with recent myocardial infarctions and eight age- and sex-matched normal volunteers were studied using CINE-bSSFP imaging to describe cyclic image intensity variations as a function of the cardiac ...
Boari Benedetta - - 2011
Congestive heart failure (CHF) is the end stage of many cardiac diseases, and one of the leading causes of mortality and morbidity around the world. Coronary heart disease and hypertension (either singly or together) are the main etiology for CHF. It has been reported that major acute cardiovascular events (myocardial ...
Hsiao Shih-Hung - - 2011
Although E/e' (the ratio of early diastolic mitral inflow velocity to early diastolic mitral annular velocity) is widely used to measure left ventricular filling pressure (LVFP), its accuracy is questionable in coronary artery disease patients. Echocardiograms and LVFP were obtained from 174 patients with stable angina (Canadian Cardiovascular Society angina ...
Kan Hirohito - - 2011
Apparent diffusion coefficients (ADCs) are sometimes overestimated when they are measured in the brain near the basal ganglia because water molecules in brain tissues fluctuate with blood volume loading in the cranium. We determined detailed ADC changes during the cardiac cycle to evaluate the appropriate cardiac phases for accurate measurement ...
Negassa Abdissa - - 2011
Objective. To identify modifiable neighborhood factors and quantify their effect on the rate of revascularization among acute myocardial infarction (AMI) patients. Method. Using the New York City hospital discharge records during 1998-2002, we employed a hierarchical regression model that integrates patient-level risk factors and neighborhood-level factors to retrospectively examine revascularization ...
Jiang He - - 2011
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a kind of heart muscle disease characterized by the gradual replacement of the right ventricular myocardium with fibrous tissue and fat. It could be the major cause of sudden cardiac death with ventricular tachycardia, and there is a variation in the history of the ...
Bergenzaun Lill - - 2011
Assessing left ventricular (LV) systolic function in a rapid and reliable way can be challenging in the critically ill patient. The purpose of this study was to evaluate the feasibility and reliability of, as well as the association between, commonly used LV systolic parameters, by using serial transthoracic echocardiography (TTE). ...
Konings Maurits K - - 2011
Recently, a non-invasive, continuous ventricular stroke volume monitoring system using skin electrodes has been developed. In contrast to impedance-based methods, the new technique (ventricular field recognition) enables measurement of changes in ventricular volume. A prototype using this new method was built (the hemologic cardiac profiler, HCP) and validated against a ...
Lombardi Federico - - 2011
Heart period constantly changes on a beat to beat basis, due to autonomic influences on the sinoatrial node, and changes can be quantified as heart rate variability (HRV). In addition, after a premature ventricular beat, there are reproducible variations in RR interval, also due to baroreflex mediated autonomic influences on ...
Pennell Dudley J DJ Royal Brompton Hospital, London, UK. - - 2011
The efficacy of cardiac iron chelation in transfusion-dependent patients has been demonstrated in one-year prospective trials. Since normalization of cardiac T2* takes several years, the efficacy and safety of deferasirox was assessed for two years in patients with β-thalassemia major in the cardiac sub-study of the EPIC trial. Eligible patients ...
Komajda Michel - - 2011
The determinants of prognosis in patients with heart failure and preserved ejection fraction (HF-PEF) are poorly documented. We evaluated data from 4128 patients in the I-PRESERVE trial (Irbesartan in Heart Failure with Preserved Ejection Fraction Study). Multivariable Cox regression models were developed using 58 baseline demographic, clinical, and biological variables ...
McEvoy John W - - 2010
Baseline coronary artery calcification (CAC) accurately identifies coronary atherosclerosis and might improve prediction of future cardiac events. Serial assessment of CAC scores has been proposed for monitoring atherosclerosis progression and for assessing the effectiveness of medical therapies aimed at reducing cardiac risk. However, whether knowledge of progression of CAC scores ...
Rauch Bernhard - - 2010
There is no randomized, double-blind trial testing the prognostic effect of highly purified omega-3 fatty acids in addition to current guideline-adjusted treatment of acute myocardial infarction. OMEGA is a randomized, placebo-controlled, double-blind, multicenter trial testing the effects of omega-3-acid ethyl esters-90 (1 g/d for 1 year) on the rate of ...
Cochet Alexandre - - 2010
To compare 2 cardiac magnetic resonance (CMR) techniques for the evaluation of the prognostic significance of microvascular damage after non ST-segment elevation myocardial infarction (NSTEMI). CMR was performed at 3T in 61 patients within the week following their first NSTEMI. A first-pass saturation-recovery gradient-echo perfusion sequence was started during the ...
Kalay Nihat - - 2010
Fatty acid-binding protein (FABP) is an independent predictor of cardiac events. However, the relation between increasing FABP and coronary atherosclerosis is unknown. We have investigated the relation between FABP and angiographic properties of coronary atherosclerosis in patients with acute coronary syndrome (ACS). The study population consisted of 93 patients with ...
Baskurt M - - 2010
Post-infarction ventricular septal defect (VSD) is a fatal mechanical complication of myocardial infarction. Although the incidence has decreased to less than 1% after the extensive use of reperfusion strategies, post-infarction VSD still carries a high mortality risk. Management is controversial, whether to wait for surgery after a stabilisation period or ...
Leeka Justin - - 2010
Physiologic and clinical triggers, including mental stress, anxiety, and anger, often precipitate acute myocardial infarction and cardiovascular death. Sporting events can acutely increase cardiovascular event and death rates. A greater impact is observed in patients with known coronary artery disease and when stressful features are present, including a passionate fan, ...
Chaptini Nayla - - 2010
Ambulatory cardiac single-photon emission computed tomography stress testing for the evaluation of coronary artery disease at the primary care physician's office is increasingly utilized without data supporting its safety. In this 2-year prospective pilot study of 1266 consecutive stress-myocardial perfusion imaging studies done in the primary care physician's office using ...
Núñez-Gil Iván J - - 2010
The Killip classification categorizes heart failure (HF) in acute myocardial infarction, and has a prognostic value. Although non-ST-elevation myocardial infarction (NSTEMI) is increasing steadily, little information is available about the prognostic value of low Killip class in this scenario. Our aim was to assess the prognostic value of mild HF ...
White Harvey - - 2010
BACKGROUND: Elevated plasma levels of lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) are associated with increased risk of cardiovascular (CV) events. Direct inhibition of this proinflammatory enzyme with darapladib may benefit CV patients when given as an adjunct to standard of care, including lipid-lowering and antiplatelet therapies. METHODS: STABILITY is a randomized, placebo-controlled, ...
Esen Ali M - - 2010
The aim of this study was to evaluate the prognostic value of different fractional flow reserve (FFR) cutoff values and corrected thrombolysis in myocardial infarction frame (TIMI) count (CTFC) measurements in a series of consecutive patients with moderate coronary lesions, including patients with unstable angina, myocardial infarction, and/or positive noninvasive ...
Galper Shira L - - 2011
This study assessed the cumulative incidence of clinically significant cardiac disease in 1279 Hodgkin lymphoma patients treated with mediastinal irradiation and quantified the standard incidence ratios (SIRs) and absolute excess risks of cardiac procedures compared with a normal matched population. Cox regression analysis was used to explore factors associated with ...
Makino Aritaka - - 2010
MIF is proatherogenic and is highly expressed in unstable atherosclerotic plaques. Circulating levels of MIF are increased in patients with impaired glucose tolerance or type 2 diabetes mellitus (IGT/T2DM). We examined whether high circulating levels of macrophage migration inhibitory factor (MIF) are related to increased risk of future coronary events ...
Hirsch Liran - - 2011
Adverse cardiovascular events (CVE) tend to peak during early morning post-waking hours. Our objective was to explore a possible correlation between early and late morning hours and flow-mediated dilation (FMD), and whether early morning FMD reduction contributes to a circadian pattern of cardiac and vascular vulnerability. Brachial FMD was prospectively ...
Ausset Sylvain - - 2010
BACKGROUND: The aim of this study performed in patients undergoing major orthopedic surgery was to assess the impact of changes in practice on both the incidence of postoperative myocardial ischemia (PMI) detected by serial measurements of troponin Ic and long-term cardiac outcome. METHODS: During a 3-yr period, troponin Ic was ...
Zhang Yi - - 2010
BACKGROUND: Left ventricular diastolic dysfunction (LVDD) was reported as a significant predictor of mortality, mainly in patients with heart failure. However, prospective data are scarce in the hospitalized elderly population. METHODS: We studied the association of severe LVDD, defined by conventional echocardiographic parameters, with cardiovascular and all-cause mortality in a ...
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