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Oxborough David - - 2012
Aims: To determine the intraobserver reproducibility of peak and temporal values for myocardial strain (ɛ) and strain rate (SR) using a speckle tracking technique in the left ventricle (LV), right ventricle (RV), and left atrium (LA). Methods and Results: Myocardial speckle tracking echocardiograms of the LV, RV, and LA were ...
Owan Theophilus E - - 2012
OBJECTIVES: We sought to examine the contemporary use of thrombectomy during primary percutaneous coronary intervention (PCI) in the United States. BACKGROUND: Adjunctive thrombectomy during primary PCI for patients with ST-segment elevation myocardial infarction (STEMI) has demonstrated mixed results. While earlier studies showed either unfavorable or neutral effects with rheolytic thrombectomy, ...
Neves Victor Ribeiro - - 2012
OBJECTIVE: Coronary artery disease (CAD) and acute myocardial infarction (AMI) are associated with a reduction of heart rate variability (HRV). The aim of this study was to compare the HRV of CAD patients with and without AMI (CAD-AMI) with health-matched controls by linear (spectral analysis) and nonlinear [Shannon entropy (SE), ...
Wu C-Y - - 2012
The prone position can reduce cardiac output by up to 25% due to reduced preload. We hypothesised that preload optimisation targeted to stroke volume variation before turning prone might alleviate this. A supine threshold stroke volume variation of 14% in a preliminary study identified patients whose cardiac outputs would decline ...
Chaichana Thanapong - - 2012
In this study, we investigate plaques located at the left coronary bifurcation. We focus on the effect that the resulting changes in wall shear stress (WSS) and wall pressure stress gradient (WPSG) have on atherosclerotic progress in coronary artery disease. Coronary plaques were simulated and placed at the left main ...
Baumert Jens - - 2012
Elevated fibrinogen levels are strongly and consistently associated with incident coronary heart disease (CHD). A possible causal contribution of fibrinogen in the pathway leading to atherothrombotic cardiovascular disease complications has been suggested. However, for implementation in clinical practice, data on validity and reliability, which are still scarce, are needed that ...
Schwartz Bryan Glen - - 2012
Various stressors trigger cardiac death. The objective was to investigate a possible relation between a stock market crash and cardiac death in a large population within the United States. We obtained daily stock market data (Dow Jones Industrial Average Index), death certificate data for daily deaths in Los Angeles County ...
Jeyaraj Darwin D Case Cardiovascular Research Institute, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. - - 2012
Sudden cardiac death exhibits diurnal variation in both acquired and hereditary forms of heart disease, but the molecular basis of this variation is unknown. A common mechanism that underlies susceptibility to ventricular arrhythmias is abnormalities in the duration (for example, short or long QT syndromes and heart failure) or pattern ...
Rowland Thomas - - 2012
Orthostatic-induced alterations in Doppler echocardiographic measures of ventricular function have not been well-defined. Identifying such changes may provide useful insights regarding the responses of these measures to variations in ventricular loading conditions. Standard assessment of mitral inflow velocity and tissue Doppler imaging (TDI) of left ventricular longitudinal myocardial velocities was ...
Evlakhov V I - - 2012
During left-ventricular myocardial ischemia, the decrease in the venous return is determined by reduction of cardiac output, which results from heart rate deceleration and decrease in left-ventricular stroke volume. The latter is related to a decrease in myocardial contractility and blood storage in the pulmonary circuit. Blood accumulation in the ...
Noori Shahab - - 2012
ObjectiveElectrical velocimetry (EV) is a non-invasive method of continuous left cardiac output monitoring based on measurement of thoracic electrical bioimpedance. The objective was to validate EV by investigating the agreement in cardiac output measurements performed by EV and echocardiography.DesignIn this prospective observational study, left ventricular output (LVO) was simultaneously measured ...
Madias John E - - 2012
The interpretation of the electrocardiogram (ECG) T-wave alternans (TWA) as positive or negative depends on its magnitude, regardless whether the frequency domain or the time domain analysis is employed. The author argues that a number of cardiac and extracardiac influences can confound the magnitude of TWA. The amplitude of the ...
Itaya Hideki - - 2012
BACKGROUND: Circadian variation has been accepted as a factor in acute myocardial infarction (AMI). An increased incidence of cardiac events in the morning has been reported for a long time. Recent reports have indicated that the onset of AMI shows two peaks, which occur in the morning and evening. It ...
Kociol Robb D RD Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715, - - 2012
ST-segment elevation myocardial infarction (STEMI) treatment has improved outcomes and shortened hospital stay. Recently, 30-day readmission rates have been proposed as a metric for care of patients with STEMI. However, international rates and predictors of 30-day readmission after STEMI have not been studied. To determine international variation in and predictors ...
Tan Hong-Wei - - 2012
The success and complication rates of atrial fibrillation (AF) ablation may be related to regional differences in left atrial (LA) wall thickness. The purpose of this study was to investigate the transmural LA wall thickness in various regions. We measured LA wall thickness in 36 human heart specimens using calipers ...
Soares-Filho Gastão Luiz Fonseca - - 2012
Chest pain, a key element in the investigation of coronary artery disease is often regarded as a benign prognosis when present in panic attacks. However, panic disorder has been suggested as an independent risk factor for long-term prognosis of cardiovascular diseases and a trigger of acute myocardial infarction. Faced ...
Miśko Jolanta - - 2012
Evaluation of myocardial perfusion and viability in patients withstable coronary artery disease have now become the basicsource of information in qualification for revascularization oroptimal medical therapy. This article describes all the availablemethods of non-invasive imaging of myocardial perfusion andviability.
Kawel Nadine - - 2012
Myocardial T1 relaxation time (T1 time) and extracellular volume fraction (ECV) are altered in the presence of myocardial fibrosis. The purpose of this study was to evaluate acquisition factors that may result in variation of measured T1 time and ECV including magnetic field strength, cardiac phase and myocardial region. 31 ...
Kawel Nadine - - 2012
Myocardial T1 relaxation time (T1 time) and extracellular volume fraction (ECV) are altered in patients with diffuse myocardial fibrosis. The purpose of this study was to perform an intra-individual assessment of normal T1 time and ECV for two different contrast agents. A modified Look-Locker Inversion Recovery (MOLLI) sequence was acquired ...
Jia En-Zhi - - 2012
The objective of this study was to explore the time distribution patterns of the onset of chest pain in subjects with acute ST-elevation myocardial infarction in a Chinese population. A total of 1467 patients with acute ST-elevation myocardial infarction were enrolled from 2003 to 2010. The hourly, daily, monthly, seasonal ...
Young Alistair A - - 2012
Recently there has been considerable interest in LV torsion and its relationship with symptomatic and pre-symptomatic disease processes. Torsion gives useful additional information about myocardial tissue performance in both systolic and diastolic function. CMR assessment of LV torsion is simply and efficiently performed. However, there is currently a wide variation ...
Hsu Po-Chao - - 2012
Coronary collateral circulation plays an important role to protect myocardium from ischemia, preserve myocardial contractility and reduce cardiovascular events. Chronic kidney disease (CKD) is associated with poor coronary collateral development and cardiovascular outcome. However, limited research investigates the predictors for collateral development in the CKD population. We evaluated 970 consecutive ...
Kohr Mark J - - 2012
Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca(2+) handling, proposed signaling pathways, and protein end-targets.
Park Seung-Jung - - 2012
For several decades of medical history, coronary-artery bypass grafting (CABG) has been regarded as the best treatment option for patients with unprotected left main coronary artery (LMCA) disease, considering lesion priority and its clinical consequences. Over the time, with remarkable advancements in techniques of percutaneous coronary intervention (PCI), supporting devices, ...
Brandão Daniella Cunha - - 2011
Were evaluated individuals divided into two groups: we studied chronic heart failure (CHF) (19 patients with CHF plus cardiomegaly) and control (12 healthy volunteers) during performance of inspiratory loaded breathing (ILB). We evaluated: spirometry, functional capacity through the six-minute walk test (6MWT), and distribution of thoracoabdominal volumes via optoelectronic plethysmography ...
Nagele Peter P Division of Clinical and Translational Research, Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. - - 2011
Perioperative myocardial infarction is a common and potentially fatal complication after noncardiac surgery, particular among patients with cardiovascular risk factors. β-blockers have been considered a mainstay in prevention and treatment of perioperative myocardial infarction, yet recent evidence suggests that β-blockers may have an unfavorable risk profile in this setting, and ...
Ungerer Jacobus P J - - 2011
BACKGROUND:Data to standardize and harmonize the differences between cardiac troponin assays are needed to support their universal status in diagnosis of myocardial infarction. We characterized the variation between methods, the comparability of the 99th-percentile cutoff thresholds, and the occurrence of outliers in 4 cardiac troponin assays.METHODS:Cardiac troponin was measured in ...
Matyal Robina - - 2011
OBJECTIVES: To investigate the effects of acute elevation in afterload on global (systolic and diastolic) myocardial function by performing serial intraoperative transesophageal echocardiograms during and after cross-clamp application on patients undergoing elective abdominal aortic aneurysm (AAA) surgery. DESIGN: A prospective observational study. SETTING: A tertiary care university hospital. PARTICIPANTS: Patients ...
Perrault Louis P LP Department of Surgery, Montreal Heart Institute, University of Montréal, Montréal, Québec, - - 2012
Ischemic mitral regurgitation, a complication of myocardial infarction and coronary artery disease more generally, is associated with a high mortality rate and is estimated to affect 2.8 million Americans. With 1-year mortality rates as high as 40%, recent practice guidelines of professional societies recommend repair or replacement, but there remains ...
Phan T D - - 2011
This study compared the cardiac output responses to haemodynamic interventions as measured by three minimally invasive monitors (Oesophageal Doppler Monitor the VigileoFlotrac and the LiDCOrapid) to the responses measured concurrently using thermodilution, in cardiac surgical patients. The study also assessed the precision and bias of these monitors in relation to ...
Jones W Schuyler - - 2011
Although variation in use of invasive coronary procedures has been shown, the relationship between invasive diagnostic cardiac catheterization (Cath) and subsequent revascularization with percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) is not known. We evaluated the temporal trends and variation in invasive Cath, PCI, and CABG across ...
Ho Siew Yen - - 2011
The anatomy of the left atrium is reviewed with relevance to various interventional transcatheter procedures requiring manoeuvres within or passage through the left atrium. The component parts of the atrium-the atrial body with a vestibule, appendage, venous component, and the atrial septum-are described with emphasis on their spatial relationships to ...
Swenson Darrell J - - 2011
The electrocardiogram (ECG) is ubiquitously employed as a diagnostic and monitoring tool for patients experiencing cardiac distress and/or disease. It is widely known that changes in heart position resulting from, for example, posture of the patient (sitting, standing, lying) and respiration significantly affect the body-surface potentials; however, few studies have ...
Chen Chun-An - - 2011
Enzyme replacement therapy (ERT) for infantile-onset Pompe disease effectively reduces the left ventricular (LV) mass. This study sought to explore detailed process of LV reverse remodeling after ERT with the use of tissue Doppler and stain rate imaging. Nine infants and children with Pompe cardiomyopathy undergoing ERT for ≥1 year, ...
Gayat Etienne - - 2011
Most techniques previously used to assess left ventricular (LV) elastance (E(es)) and ventricular-arterial coupling (C(LV-A)) relied on invasive measurements and data acquisition over a wide range of loading conditions. Our goals were to: (1) assess the feasibility of noninvasive assessment of E(es) and C(LV-A) using real-time three-dimensional echocardiography (RT3DE) and ...
Christensen Jared D - - 2011
The purpose of this article is to assess whether iopamidol-370 provides superior vascular contrast of the coronaries and depiction of anatomic detail without affecting heart rate and beat-to-beat variability during coronary dual-source MDCT compared with iodixanol-320. In this prospective trial, coronary CT angiography was performed on 60 adult patients using ...
Zerbe Philipp - - 2011
Objective-To noninvasively evaluate physiologic postprandial adaptations of the heart in snakes. Animals-6 juvenile Paraguay anacondas (Eunectes notaeus). Procedures-The heart of each anaconda was echocardiographically evaluated after food was withheld for 28 days as well as 3 and 10 days after feeding. Physical measurements included body length, weight, and circumference at ...
Rolfes Christopher D - - 2011
Atrial fibrillation (AF) causes a continuum of atrial anatomical remodeling. Using a library of perfusion-fixed human hearts, specimens with AF were compared to controls. During this preliminary assessment study, direct measurements were taken of atrial volume, pulmonary vein (PV) circumference, and left atrial (LA) wall thicknesses. Hearts with AF typically ...
Katti Karuna - - 2011
Clinical cardiac procedures such as electrophysiology studies, catheter ablation of arrhythmias, retrograde cardioplegia delivery, cardiac resynchronization therapy and, more recently, percutaneous mitral annuloplasty, involve cannulation of the coronary sinus (CS). The presence of a membrane closing the orifice of the CS may cause difficulties during these interventions. Thus, detailed knowledge ...
Ando Makoto - - 2011
BACKGROUND: Presently, there are wide variations in cardiac anatomies requiring single ventricular palliation and these variations may have an impact on the incidence of atrioventricular valve regurgitation. METHODS: In all, 363 patients underwent single ventricular palliation (1978 to 2008). Hearts were first classified into single right ventricle (156), single left ...
Chan Paul S PS Saint Luke's Mid America Heart and Vascular Institute, 4401 Wornall Rd, Fifth Floor, Kansas City, MO 64111, USA. - - 2011
Despite the widespread use of percutaneous coronary intervention (PCI), the appropriateness of these procedures in contemporary practice is unknown. To assess the appropriateness of PCI in the United States. Multicenter, prospective study of patients within the National Cardiovascular Data Registry undergoing PCI between July 1, 2009, and September 30, 2010, ...
Iqbal Toqueer - - 2011
Coronary artery diseases encompass a spectrum of disorders ranging from angina to fatal myocardial infarctions with the main underlying pathology being identified as atherosclerosis. The level of inflammatory markers, C-reactive protein and fibrinogen was determined in hundred patients with established coronary artery disease and correlated with lipid profile which included ...
Lloyd Christopher W - - 2011
Myocardial tissue characterization represents an extension of currently available echocardiographic imaging. The systematic variation of backscattered energy during the cardiac cycle (the "cyclic variation" of backscatter) has been employed to characterize cardiac function in a wide range of investigations. However, the mechanisms responsible for observed cyclic variation remain incompletely understood. ...
Karabag Turgut - - 2011
Background: Our aim was to investigate whether diastolic functions, myocardial velocities and pulmonary vein flow show diurnal variation within a 24-hour day. Method and Results: Fourty-four healthy subjects with no history of cardiovascular or systemic diseases (32 males, 12 females; mean age 34.7 ± 8.7 years, mean BMI: 25.5 ± ...
Kilbourne Barbara J - - 2011
: Coronary heart disease often presents with ST segment elevation acute myocardial infarction (STEMI). The American College of Cardiology/American Heart Association guidelines stress prompt reperfusion for STEMI. Examining geographic variations in treatment with PPCI (percutaneous primary coronary intervention) and CABG (coronary artery bypass graft) among metropolitan, micropolitan and non-micropolitan rural ...
Koplay Mustafa - - 2011
PURPOSE: The left atrial appendage (LAA) is usually known as a long, tubular, hooked structure derived from the left atrium. However, it varies widely in terms of anatomical shape. In this study, anatomical shape variations of the LAA were investigated and classified in vivo in a large group of patients ...
Becker Cristoph R - - 2011
OBJECTIVES:: To compare a contrast agent with high iodine concentration with an iso-osmolar contrast agent for coronary dual-source computed tomography angiography (DS-CTA), and to assess whether the contrast agent characteristics may affect the diagnostic quality of coronary DS-CTA. MATERIALS AND METHODS:: Patients were randomized to receive either 80 mL of ...
Goldfarb James W - - 2011
To evaluate the dependence of CINE-balanced steady-state free precession (bSSFP) image intensities on spatial location, cardiac phase, and disease state. Eight subjects with recent myocardial infarctions and eight age- and sex-matched normal volunteers were studied using CINE-bSSFP imaging to describe cyclic image intensity variations as a function of the cardiac ...
Boari Benedetta - - 2011
Congestive heart failure (CHF) is the end stage of many cardiac diseases, and one of the leading causes of mortality and morbidity around the world. Coronary heart disease and hypertension (either singly or together) are the main etiology for CHF. It has been reported that major acute cardiovascular events (myocardial ...
Hsiao Shih-Hung - - 2011
Although E/e' (the ratio of early diastolic mitral inflow velocity to early diastolic mitral annular velocity) is widely used to measure left ventricular filling pressure (LVFP), its accuracy is questionable in coronary artery disease patients. Echocardiograms and LVFP were obtained from 174 patients with stable angina (Canadian Cardiovascular Society angina ...
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