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Nural-Guvener Hikmet F - - 2012
Cardiovascular (CV) diseases are known to have a negative impact on the brain and neurocognition, and contribute to the development of vascular dementia and neurodegenerative diseases such as Alzheimer's disease (AD). Among CV diseases, congestive heart failure (CHF) after myocardial infarction (MI) is a condition where the ability of the ...
Vijayaraghavan G - - 2012
Tropical endomyocardial fibrosis in India was a common medical problem in the coastal districts of south India, especially the Kerala State. The clinical and autopsy studies have shown left and right ventricular apical fibrosis, with varying degree of atrioventricular valve regurgitation. Left ventricular endomyocardial fibrosis presents with severe pulmonary hypertension ...
Falase A O AO Division of Cardiovascular Medicine, Department of Medicine, University College Hospital, Ibadan, Oyo State, Nigeria. - - 2012
A review of heart diseases in Africa shows that the cardiomyopathies continue to be important causes of morbidity and mortality in the population. Hypertension remains the commonest cause of myocardial disease, followed by the cardiomyopathies. Ischaemic heart disease continues to be rare. Of the cardiomyopathies, dilated cardiomyopathy (DCM) is still ...
Ahmed W - - 2012
Introduction: To study the angiographic disease severity of the infarct vessel after thrombolysis in patients with acute ST-elevation myocardial infarction and their 90 days outcome. Methods: We conducted a retrospective analysis of a prospectively maintained cardiology database at Shifa International Hospital from February 2011 to August 2011. A total of ...
Edelman J James B - - 2012
Patterns of myocardial revascularization have changed significantly over the past decade. There has been a relative decrease of coronary artery bypass grafting (CABG) compared with percutaneous coronary intervention (PCI) and some patients are undergoing PCI for coronary lesions traditionally reserved for CABG. The mid- to long-term results of several trials ...
Tousoulis Dimitris - - 2012
Atherosclerosis is a chronic disease which mainly represents an inflammatory response in the vessels. Myocardial ischemia manifested by angina pectoris can be either acute or chronic and usually is a result of imbalance between myocardial oxygen supply and myocardial oxygen demand. Chronic stable angina is chest discomfort attributed to myocardial ...
Kim Jun - - 2012
Herein, we present a case of a successful catheter ablation of ventricular tachycardia (VT) using a radial artery approach in a post-myocardial infarction patient, who had an implantable cardioverter-defibrillator and peripheral artery disease. Although the patient did not use antiarrhythmic drugs, the patient experienced no recurrence of VT during the ...
Tokuda Michifumi - - 2012
BACKGROUND: -Catheter ablation of ventricular tachycardia (VT) in non-ischemic heart diseases can be challenging and outcomes across different diseases are incompletely defined. The aim of this study is to describe the outcomes following catheter ablation for non-ischemic VT in a large cohort and compare the electrophysiological findings and outcomes according ...
Barbosa Carolina Esteves - - 2012
BACKGROUND: The accuracy of the GRACE and TIMI scores in predicting coronary disease extension in patients with non-ST-elevation acute coronary syndromes (ACS) has not been established. OBJECTIVE: To assess the hypothesis that the GRACE and TIMI risk scores satisfactorily predict coronary disease extension in patients withnon-ST-elevation ACS undergoing coronary angiography. ...
Sado Daniel M DM The Heart Hospital, 16-18 Westmoreland St, London W1G 8PH, - - 2012
To measure and assess the significance of myocardial extracellular volume (ECV), determined non-invasively by equilibrium contrast cardiovascular magnetic resonance, as a clinical biomarker in health and a number of cardiac diseases of varying pathophysiology. Prospective study. Tertiary referral cardiology centre in London, UK. 192 patients were mainly recruited from specialist ...
Frustaci Andrea A Cardiovascular, Respiratory, Nephrologic and Geriatric Sciences Department, La Sapienza University, 00161 Rome, Italy. - - 2013
Hypertrophic cardiomyopathy phenotype is shared by heterogeneous entities. The purpose of the study was to evaluate the diagnostic role of left ventricular endomyocardial biopsy. One hundred fifty-one consecutive patients with unexplained left ventricular hypertrophy and normal/elevated QRS voltages or left bundle-branch block underwent left ventricular endomyocardial biopsy because of associated ...
Göktekin Omer - - 2012
Abstract. The rate of percutaneous coronary intervention for acute ST-segment elevation myocardial infarction varies between European countries. The variations arise partly because of differences between countries in the primary percutaneous coronary intervention network system. The lack of an organised primary percutaneous coronary intervention network system in Turkey was the main ...
Zhang Mingchang - - 2012
It is unclear if the extent of coronary atherosclerosis is associated with increase in heart muscle mass. We retrospectively reviewed autopsy reports of sudden coronary deaths occurring in a statewide medical examiner system over a one-year period. Cardiomegaly was assessed by height, and given a score of 0-4 based on ...
van Nierop Bastiaan J - - 2012
In this article, we present a first-pass perfusion imaging protocol to determine quantitative regional perfusion values (in mL min(-1)  g(-1) ) of the mouse myocardium. Perfusion was quantified using a Fermi-constrained deconvolution of the myocardial tissue response with the arterial input function. A dual-bolus approach was implemented. Experimental evidence is presented ...
Wijnbergen I - - 2012
OBJECTIVES: The aim of our study was to investigate the circadian and weekly variation and assess the influence of environmental variables on the occurrence of acute myocardial infarction (AMI). METHODS: Our study population consisted of 2983 consecutive patients admitted with AMI between January 2006 and May 2008. Data were abstracted ...
Hamada Sandra - - 2012
Direct planimetry of anatomic regurgitation orifice area (AROA) using 3-dimensional transesophageal echocardiography (TEE) has been described. This study sought to (1) compare mitral valve regurgitant volume (RV) derived by AROA using 3-dimensional TEE with RV obtained by cardiac magnetic resonance (CMR) imaging and (2) determine the impact of AROA and ...
Scharnhorst Volkher - - 2012
BACKGROUND:New-generation high-sensitivity assays for cardiac troponin have lower detection limits and less imprecision than earlier assays. Reference 99th-percentile cutoff values for these new assays are also lower, leading to higher frequencies of positive test results. When cardiac troponin concentrations are minimally increased, serial testing allows discrimination of myocardial infarction from ...
Patel Vimal - - 2012
Sudden cardiac death in an athlete is a rare and heartrending event, often occurring in the absence of warning symptoms. The causes of sudden cardiac death in athletes are age dependent and demonstrate a degree of geographical variation. Pre-participation screening is recommended by both the European Society of Cardiology and ...
Hacioglu Yalcin - - 2012
Occasionally, electrophysiological interventions are complicated by an unusual or an anomalous cardiovascular anatomy. We report our experience of a case of situs ambiguous and symptomatic heart failure of which anomalous venous anatomy and coronary sinus variation had prevented a successful endocardial placement of a left ventricular lead for cardiac synchronization ...
Klepach Doron - - 2012
Cardiac growth and remodeling in the form of chamber dilation and wall thinning are typical hallmarks of infarct-induced heart failure. Over time, the infarct region stiffens, the remaining muscle takes over function, and the chamber weakens and dilates. Current therapies seek to attenuate these effects by removing the infarct region ...
Morton Geraint - - 2012
AIMS: To evaluate the inter-study reproducibility of quantitative cardiovascular magnetic resonance (CMR) myocardial perfusion imaging and the influence of diurnal variation on perfusion. Data on these are limited, despite being crucially important for performing serial examinations both in clinical practice and in trials. METHODS AND RESULTS: Sixteen healthy volunteers underwent ...
Haas Sebastian - - 2012
BACKGROUND: The pleth variability index (PVI) is derived from analysis of the plethysmographic curve and is considered to be a noninvasive parameter for prediction of volume responsiveness. The aim of our prospective clinical study was to evaluate if volume responsiveness can be predicted by PVI in patients undergoing cardiac surgery ...
Hsieh Bill P C - - 2012
Contrast enhanced multi-detector computed tomography (MDCT) may detect left atrial appendage (LAA) thrombus; however, its ability to qualify LAA stasis has not been studied. We sought to identify MDCT derived LAA radiographic parameters which could qualify LAA stasis as defined by established transesophageal echocardiography (TEE) parameters. Pre-procedural MDCT followed by ...
Oxborough David - - 2012
Aims: To determine the intraobserver reproducibility of peak and temporal values for myocardial strain (ɛ) and strain rate (SR) using a speckle tracking technique in the left ventricle (LV), right ventricle (RV), and left atrium (LA). Methods and Results: Myocardial speckle tracking echocardiograms of the LV, RV, and LA were ...
Owan Theophilus E - - 2012
OBJECTIVES: We sought to examine the contemporary use of thrombectomy during primary percutaneous coronary intervention (PCI) in the United States. BACKGROUND: Adjunctive thrombectomy during primary PCI for patients with ST-segment elevation myocardial infarction (STEMI) has demonstrated mixed results. While earlier studies showed either unfavorable or neutral effects with rheolytic thrombectomy, ...
Neves Victor Ribeiro - - 2012
OBJECTIVE: Coronary artery disease (CAD) and acute myocardial infarction (AMI) are associated with a reduction of heart rate variability (HRV). The aim of this study was to compare the HRV of CAD patients with and without AMI (CAD-AMI) with health-matched controls by linear (spectral analysis) and nonlinear [Shannon entropy (SE), ...
Wu C-Y - - 2012
The prone position can reduce cardiac output by up to 25% due to reduced preload. We hypothesised that preload optimisation targeted to stroke volume variation before turning prone might alleviate this. A supine threshold stroke volume variation of 14% in a preliminary study identified patients whose cardiac outputs would decline ...
Chaichana Thanapong - - 2012
In this study, we investigate plaques located at the left coronary bifurcation. We focus on the effect that the resulting changes in wall shear stress (WSS) and wall pressure stress gradient (WPSG) have on atherosclerotic progress in coronary artery disease. Coronary plaques were simulated and placed at the left main ...
Baumert Jens - - 2012
Elevated fibrinogen levels are strongly and consistently associated with incident coronary heart disease (CHD). A possible causal contribution of fibrinogen in the pathway leading to atherothrombotic cardiovascular disease complications has been suggested. However, for implementation in clinical practice, data on validity and reliability, which are still scarce, are needed that ...
Schwartz Bryan Glen - - 2012
Various stressors trigger cardiac death. The objective was to investigate a possible relation between a stock market crash and cardiac death in a large population within the United States. We obtained daily stock market data (Dow Jones Industrial Average Index), death certificate data for daily deaths in Los Angeles County ...
Jeyaraj Darwin - - 2012
Sudden cardiac death exhibits diurnal variation in both acquired and hereditary forms of heart disease, but the molecular basis of this variation is unknown. A common mechanism that underlies susceptibility to ventricular arrhythmias is abnormalities in the duration (for example, short or long QT syndromes and heart failure) or pattern ...
Rowland Thomas - - 2012
Orthostatic-induced alterations in Doppler echocardiographic measures of ventricular function have not been well-defined. Identifying such changes may provide useful insights regarding the responses of these measures to variations in ventricular loading conditions. Standard assessment of mitral inflow velocity and tissue Doppler imaging (TDI) of left ventricular longitudinal myocardial velocities was ...
Evlakhov V I - - 2012
During left-ventricular myocardial ischemia, the decrease in the venous return is determined by reduction of cardiac output, which results from heart rate deceleration and decrease in left-ventricular stroke volume. The latter is related to a decrease in myocardial contractility and blood storage in the pulmonary circuit. Blood accumulation in the ...
Noori Shahab - - 2012
ObjectiveElectrical velocimetry (EV) is a non-invasive method of continuous left cardiac output monitoring based on measurement of thoracic electrical bioimpedance. The objective was to validate EV by investigating the agreement in cardiac output measurements performed by EV and echocardiography.DesignIn this prospective observational study, left ventricular output (LVO) was simultaneously measured ...
Madias John E - - 2012
The interpretation of the electrocardiogram (ECG) T-wave alternans (TWA) as positive or negative depends on its magnitude, regardless whether the frequency domain or the time domain analysis is employed. The author argues that a number of cardiac and extracardiac influences can confound the magnitude of TWA. The amplitude of the ...
Itaya Hideki - - 2012
BACKGROUND: Circadian variation has been accepted as a factor in acute myocardial infarction (AMI). An increased incidence of cardiac events in the morning has been reported for a long time. Recent reports have indicated that the onset of AMI shows two peaks, which occur in the morning and evening. It ...
Kociol Robb D - - 2012
ST-segment elevation myocardial infarction (STEMI) treatment has improved outcomes and shortened hospital stay. Recently, 30-day readmission rates have been proposed as a metric for care of patients with STEMI. However, international rates and predictors of 30-day readmission after STEMI have not been studied. To determine international variation in and predictors ...
Tan Hong-Wei - - 2012
The success and complication rates of atrial fibrillation (AF) ablation may be related to regional differences in left atrial (LA) wall thickness. The purpose of this study was to investigate the transmural LA wall thickness in various regions. We measured LA wall thickness in 36 human heart specimens using calipers ...
Soares-Filho Gastão Luiz Fonseca - - 2012
Chest pain, a key element in the investigation of coronary artery disease is often regarded as a benign prognosis when present in panic attacks. However, panic disorder has been suggested as an independent risk factor for long-term prognosis of cardiovascular diseases and a trigger of acute myocardial infarction. Faced ...
Miśko Jolanta - - 2012
Evaluation of myocardial perfusion and viability in patients withstable coronary artery disease have now become the basicsource of information in qualification for revascularization oroptimal medical therapy. This article describes all the availablemethods of non-invasive imaging of myocardial perfusion andviability.
Kawel Nadine - - 2012
Myocardial T1 relaxation time (T1 time) and extracellular volume fraction (ECV) are altered in the presence of myocardial fibrosis. The purpose of this study was to evaluate acquisition factors that may result in variation of measured T1 time and ECV including magnetic field strength, cardiac phase and myocardial region. 31 ...
Kawel Nadine - - 2012
Myocardial T1 relaxation time (T1 time) and extracellular volume fraction (ECV) are altered in patients with diffuse myocardial fibrosis. The purpose of this study was to perform an intra-individual assessment of normal T1 time and ECV for two different contrast agents. A modified Look-Locker Inversion Recovery (MOLLI) sequence was acquired ...
Jia En-Zhi - - 2012
The objective of this study was to explore the time distribution patterns of the onset of chest pain in subjects with acute ST-elevation myocardial infarction in a Chinese population. A total of 1467 patients with acute ST-elevation myocardial infarction were enrolled from 2003 to 2010. The hourly, daily, monthly, seasonal ...
Young Alistair A - - 2012
Recently there has been considerable interest in LV torsion and its relationship with symptomatic and pre-symptomatic disease processes. Torsion gives useful additional information about myocardial tissue performance in both systolic and diastolic function. CMR assessment of LV torsion is simply and efficiently performed. However, there is currently a wide variation ...
Hsu Po-Chao - - 2012
Coronary collateral circulation plays an important role to protect myocardium from ischemia, preserve myocardial contractility and reduce cardiovascular events. Chronic kidney disease (CKD) is associated with poor coronary collateral development and cardiovascular outcome. However, limited research investigates the predictors for collateral development in the CKD population. We evaluated 970 consecutive ...
Kohr Mark J - - 2012
Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca(2+) handling, proposed signaling pathways, and protein end-targets.
Park Seung-Jung - - 2012
For several decades of medical history, coronary-artery bypass grafting (CABG) has been regarded as the best treatment option for patients with unprotected left main coronary artery (LMCA) disease, considering lesion priority and its clinical consequences. Over the time, with remarkable advancements in techniques of percutaneous coronary intervention (PCI), supporting devices, ...
Brandão Daniella Cunha - - 2011
Were evaluated individuals divided into two groups: we studied chronic heart failure (CHF) (19 patients with CHF plus cardiomegaly) and control (12 healthy volunteers) during performance of inspiratory loaded breathing (ILB). We evaluated: spirometry, functional capacity through the six-minute walk test (6MWT), and distribution of thoracoabdominal volumes via optoelectronic plethysmography ...
Nagele Peter - - 2011
Perioperative myocardial infarction is a common and potentially fatal complication after noncardiac surgery, particular among patients with cardiovascular risk factors. β-blockers have been considered a mainstay in prevention and treatment of perioperative myocardial infarction, yet recent evidence suggests that β-blockers may have an unfavorable risk profile in this setting, and ...
Ungerer Jacobus P J - - 2011
BACKGROUND:Data to standardize and harmonize the differences between cardiac troponin assays are needed to support their universal status in diagnosis of myocardial infarction. We characterized the variation between methods, the comparability of the 99th-percentile cutoff thresholds, and the occurrence of outliers in 4 cardiac troponin assays.METHODS:Cardiac troponin was measured in ...
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