Search Results
Results 351 - 400 of 924
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Guglin Maya - - 2007
Managing volume overload is essential for the treatment of symptomatic heart failure. Traditionally, it is achieved with oral and intravenous diuretics. Alternatively, the excess fluid can be removed via ultrafiltration. Modern technology has made this latter option more feasible than before for routine clinical practice. In this article we review ...
Kline Kay Setter - - 2007
This study examined the effects of 2 home healthcare nursing approaches--supportive-educative and mutual goal setting--on self-management for patients with heart failure. Both approaches are specifically related to participants' understanding of heart failure and self-efficacy in managing the condition. An experimental, longitudinal, repeated-measures design was used with a sample of 88 ...
Cavallari Larisa H - - 2007
Cardiac fibrosis plays an important role in the pathophysiology of heart failure. The authors sought to determine whether biomarkers of cardiac fibrosis for milder clinical degrees of heart failure are comparable to those of more advanced disease. Procollagen types I and III amino-terminal peptides (PINP and PIIINP) and type I ...
Mosterd Arend - - 2007
The aim of this paper is to review the clinical epidemiology of heart failure. The last paper comprehensively addressing the epidemiology of heart failure in Heart appeared in 2000. Despite an increase in manuscripts describing epidemiological aspects of heart failure since the 1990s, additional information is still needed, as indicated ...
de Korte M A - - 2007
Trastuzumab can induce cardiotoxicity, particularly when combined with anthracyclines. Myocardial human epidermal growth factor receptor 2 (HER2) expression may be transiently upregulated by a compensatory mechanism following cardiac stress. 111In-DTPA-trastuzumab, scintigraphy can detect HER2 positive tumour lesions, however previously, we found myocardial uptake in only 1 of the 15 anthracycline-pre-treated ...
Balakumar, Pitchai
Heart failure is associated with high morbidity and mortality and is proving to be an economic burden in developing countries. A number of therapeutic agents are presently employed in heart failure; but they are not sufficient to control symptoms of heart failure. Moreover, the prevalence of chronic heart failure is ...
Mannheimer Buster - - 2007
OBJECTIVE: To study the validity and reliability of the new disease-specific extension of the CHP, Cardiac Health Profile congestive heart failure (CHPchf), used to assess QoL specifically for patients with heart failure. METHODS: Eighty-three consecutive patients with chronic heart failure were enrolled. Criteria and construct validity were studied by correlating ...
Erdmann Erland - - 2007
OBJECTIVE: PROspective pioglitAzone Clinical Trial In macroVascular Events (PROactive) enrolled patients with type 2 diabetes and preexisting cardiovascular disease. These patients were at high risk for heart failure, so any therapeutic benefit could potentially be offset by risk of associated heart failure mortality. We analyzed the heart failure cases to ...
Lockhart C J - - 2008
BACKGROUND: We present two clinical cases from a single institution where a final diagnosis of cardiac failure was made following the initial finding of ascites and an elevated CA 125 level. In both cases gynaecological malignancy was initially suspected. METHODS: Following negative confirmatory tests for gynaecological malignancy, echocardiography was undertaken. ...
Brack Thomas - - 2007
BACKGROUND: Cheyne-Stokes respiration (CSR) frequently occurs in patients with severe heart failure during sleep and may increase mortality. Daytime CSR supposedly poses an even greater risk, but its prevalence and prognostic importance remain elusive. Therefore, we investigated the circadian prevalence of CSR and its influence on survival in patients with ...
Conca Cristina - - 2008
BACKGROUND: Real-time 3-dimensional echocardiography (RT3DE) to visualize the coronary sinus (CS) was compared with multislice cardiac tomography (MSCT). METHODS: In all, 37 consecutive patients undergoing MSCT received RT3DE a few hours later. Group A (n = 22) had normal left ventricular dimension/function, whereas group B (n = 15) had heart ...
Kostin Sawa - - 2007
Focal disorganization of gap junctional distribution and down-regulation of the major gap junctional protein connexin 43 are typical features of myocardial remodelling in the failing human heart. Increasing evidence indicates that connexin 43 interacts with zonula-occludens-1 (ZO-1), and it has recently been shown that ZO-1 promotes the formation and growth ...
Sica Domenic A - - 2007
Thiamine, or vitamin B1, is a water-soluble B complex vitamin that was first discovered in 1910 in the process of exploring how rice bran cured patients of beriberi. Thiamine is not synthesized in humans, therefore its availability for necessary cellular processes hinges on its continual ingestion. The amount of thiamine ...
Brigadeau François - - 2007
It has been reported that high intramyocardial peroxisome proliferator-activated receptor alpha (PPARalpha) stimulation or overexpression altered cardiac contractile function in mouse models of cardiac hypertrophy and heart failure. Nevertheless, it has never been demonstrated that clinically relevant doses of drugs stimulating PPARalpha activity such as fenofibrate increase the risk to ...
El-Armouche Ali - - 2007
Cardiac myosin-binding protein-C (cMyBP-C) is an important regulator of cardiac contractility, and its phosphorylation by PKA is a mechanism that contributes to increased cardiac output in response to beta-adrenergic stimulation. It is presently unknown whether heart failure alters cMyBP-C phosphorylation. The present study determined the level of phosphorylated cMyBP-C in ...
Davidson Patricia M - - 2007
BACKGROUND: Patients with heart failure have higher mortality rates than those with most malignant diseases. The heart failure illness trajectory is one of gradual decline characterized by unpredictable events such as acute decompensation of heart failure or a sudden cardiac death. Health professionals have an obligation to give patients and ...
Olkowski A A - - 2007
Modern strains of fast-growing meat type poultry are highly susceptible to heart failure. Heart-related mortalities are observed predominantly in fast-growing broiler chickens, with ascites and sudden death syndrome being the most common heart-related conditions in modern broiler flocks. This paper examines the role of structural, molecular, and biochemical factors pertinent ...
Abdel-Qadir Husam M - - 2007
PURPOSE OF REVIEW: The purpose of this review is to summarize the recent literature regarding the familial heritability of heart failure and to discuss the possible mechanisms through which this risk is mediated. RECENT FINDINGS: Data from the Framingham Heart Study recently showed that the parental occurrence of heart failure ...
Mahmud Mobusher - - 2007
Right heart failure most commonly results from the complication of left heart failure (systolic or nonsystolic dysfunction) or pulmonary hypertension. Over the past decade, greater attention has been paid to the role of right ventricular failure in the morbidity and mortality associated with cardiomyopathy and pulmonary hypertension. The right ventricle ...
Moore Brian - - 2007
Oxygen consumption (VO2) has previously been used for prognosis and risk stratification in patients with heart failure. More recent research has introduced VE/VCO2 slope as a prognostic measure. Risk of mortality is thought to increase when VE/VCO2 slope values are greater than 34. Therefore, the purpose of this study was ...
Shroff Gautam R - - 2007
The magnitude of burden imposed by heart failure on society has necessitated the evolution of innovative strategies to identify specific avenues of treatment and the populations at highest risk. Multiple studies have demonstrated a higher burden of cardiovascular disease in black Americans. It has also been shown that the clinical ...
Bursi Francesca - - 2007
BACKGROUND: There is a paucity of data on the prognostic role of C-reactive protein (CRP) measured after myocardial infarction. We prospectively examined the association of CRP with heart failure and death among patients with myocardial infarction in the community. METHODS AND RESULTS: All Olmsted County residents who had a myocardial ...
Olkowski A A - - 2007
In order to explain the biochemical mechanisms associated with deteriorating heart function in broiler chickens, this study compared myocardial high energy phosphate substrates in leghorns, feed restricted (Broilers-Res) broilers, ad libitum fed broilers (Broilers-AL), and in broilers that developed heart failure and ascites. The profile of adenine nucleotide content in ...
Townsend DeWayne - - 2007
Duchenne muscular dystrophy (DMD) is a fatal disease of striated muscle deterioration resulting from the loss of the cytoskeletal protein dystrophin. Most patients develop significant cardiomyopathy, with heart failure being the second leading cause of death in DMD. Compared with the extensive studies on skeletal muscle defects and potential therapy ...
Ho Yi-Lwun - - 2007
BACKGROUND/PURPOSE: The influence of home- and clinic-based caring system on the economic burden of heart failure remains unknown. METHODS: Between January 2004 and December 2004, chronic heart failure patients who were followed up by specialist nurse-led telephone visiting regularly were enrolled. Clinical and economic data half a year before enrollment ...
Lipina Radim - - 2007
INTRODUCTION: Late failure of originally successful endoscopic third ventriculostomy (ETV) is considerably less common than failure of ventriculo-peritoneal (V-P) shunt in treatment of hydrocephalus. Death in consequence of late ETV failure is a very rare complication, so far having been mentioned in literature in 13 patients only. CASE REPORT: We ...
Ho Hee Hwa - - 2008
We described a patient who presented with symptoms of heart failure and was found to have diastolic heart failure. Several investigations pointed to the diagnosis of constrictive pericarditis which was later confirmed by cardiac catheterisation. The etiology turns out to be primary cardiac lymphoma which is extremely rare in immunocompetent ...
Laing James G - - 2007
BACKGROUND: Reduced expression of the major gap junction protein connexin 43 (Cx43) in the failing human heart may lead to arrhythmias and sudden cardiac death. Cx43 interacts with the actin binding protein, zonula occludens-1 (ZO-1), and it has recently been demonstrated that ZO-1 regulates the formation and function of Cx43 ...
Roberts Felicia - - 2007
OBJECTIVE: To examine the evidence regarding the safety of metformin in heart failure. DATA SOURCES: Searches in MEDLINE and International Pharmaceutical Abstracts were performed (1966-February 2007). Search terms included metformin, heart failure, lactic acidosis, clinical trials, and insulin resistance. STUDY SELECTION AND DATA EXTRACTION: Published studies and case reports that ...
Brack Thomas - - 2007
Cheyne-Stokes respiration (CSR) during the day and at night is common in patients with severe heart failure. CSR harms the failing heart through recurrent sympathetic overstimulation caused by sleep disturbances and intermittent hypoxia brought about by apnoea and hypopnoea. CSR impairs patients' quality of life and wakefulness, and probably also ...
Birmingham C L - - 2007
OBJECTIVE: To report the presentation and causes of heart failure complicating anorexia nervosa (AN). METHOD: Report of a case of heart failure occurring in a patient with AN and a review of the literature. RESULTS: A 56 year old woman with a 25 year history of AN binge-purge subtype experienced ...
Gott Merryn - - 2007
OBJECTIVES: To explore dying trajectories in heart failure. DESIGN: Prospective, longitudinal study. SETTING: Sixteen GP surgeries in four demographically contrasting areas of the UK. PARTICIPANTS: A total of 27 heart failure patients, >60 years of age, who completed questionnaires for at least five time-points before death. MAIN OUTCOME MEASURES: Kansas ...
Welch William C - - 2007
Anterior cervical plate (ACP) failure is rarely addressed in the literature. In this retrospective, observational, longitudinal, cohort study, the objectives were to (1) identify incidences of in vivo biomechanical failure in commercially available, US Food and Drug Administration-approved ACP systems, (2) describe modes of failure, (3) suggest structural explanations for ...
Balakumar Pitchai - - 2007
Heart failure, a complex disorder with heterogeneous aetiologies remains one of the most threatening diseases known. It is a clinical syndrome attributable to a multitude of factors that begins with the compensatory response known as hypertrophy, followed by a decompensated state that finally results in heart failure. Given the lack ...
van der Merwe Juliana - - 2007
We present a case of a patient with longstanding transfusion-dependent congenital dyserythropoietic anaemia (CDA) who developed cardiomyopathy despite iron chelation therapy. She presented with severe heart failure that responded poorly to conventional therapy, recovering only when therapy was augmented with metabolic agents including antioxidants and with increased iron chelation. The ...
Merkle Sabine - - 2007
Apoptosis of cardiomyocytes is increased in heart failure and has been implicated in disease progression. The activation of "proapoptotic" caspases represents a key step in cardiomyocyte apoptosis. In contrast, the role of "proinflammatory" caspases (caspases 1, 4, 5, 11, 12) is unclear. Here, we study the cardiac function of caspase-1. ...
Rastan A J - - 2007
We report on a male newborn requiring repair of a huge left apical diverticulum leading to progressive heart failure and extensive ventricular arrhythmia. At the age of 11 days, a modified Dor procedure using an autologous endoventricular pericardial patch was performed. Postoperatively, a significant reduction of ventricular extrasystole was evident. ...
Leier Carl V - - 2007
The major components and merits of the physical examination of patients with heart failure are presented. A staging of the physical examination practiced by most heart failure specialists is proposed based on the information needed at the time of the encounter. The challenges to our subspecialty regarding this diagnostic tool ...
St─ânescu Cristina - - 2007
Thyroid hormones have many effects on the heart and vascular system. Although cardiac output is reduced in hypothyroidism, heart failure is relatively rare because there is a lower demand for peripheral oxygen delivery. Hypothyroidism may also result in accelerated atherosclerosis and coronary artery disease. We report the case of a ...
Nakagawa Daisuke - - 2007
BACKGROUND: In patients with aortic stenosis (AS), the clinical outcome worsens after the development of angina, syncope, and heart failure. This study was performed to elucidate whether the outcome with AS was also poor in patients with diastolic heart failure. METHODS AND RESULTS: Fifty-two patients who had undergone aortic valve ...
Krumholz Harlan M - - 2007
To complement the current process measures for treating patients with heart attacks and with heart failure, which target gaps in quality but do not capture patient outcomes, the Centers for Medicare and Medicaid Services (CMS) has proposed the public reporting of hospital-level thirty-day mortality for these conditions in 2007. We ...
Dursunoglu Nese - - 2007
A 55-year-old man with acute myocardial infarction and no heart failure, had episodes of severe oxygen desaturation and apnea, while his hemodynamic parameters were stable. Sleep recordings revealed severe sleep apnea, and pulmonary function tests showed bronchial obstruction. Apnea and desaturation resolved on bi-level positive airway pressure. Patients with acute ...
Iversen Per Ole - - 2007
Recent epidemiological research indicates that a coexistent anemia among patients with heart failure might worsen their prognosis. However, whether the reduced synthesis of red blood cells is a contributing factor to the development and progression to overt heart failure, or whether it simply is a mere consequence of a dysfunctional ...
Blum Nava - - 2007
Generally, the sauna bathing has been contraindicated for patients with chronic heart failure. However, it has been well tolerated and improved hemodynamics has been shown in patients with chronic heart failure after a single exposure and after a four-week period of sauna bathing (five days per week). Left ventricular ejection ...
Ismail Hassan M - - 2007
Hyperthyroidism may present with signs and symptoms related to dysfunction of a variety of organs. Cardiovascular pathology in hyperthyroidism is common. A few case reports describe isolated right heart failure, tricuspid regurgitation, and pulmonary hypertension as the prominent cardiovascular manifestations of hyperthyroidism. Although most textbooks do not mention hyperthyroidism as ...
Glauber Mattia M CNR Institute of Clinical Physiology 'G. Pasquinucci' Hospital, Via Aurelia Sud, 54100 Massa, - - 2007
Presentation of the revascularization of ischemized myocardium: beating heart technique using pump-assisted extracorporeal circulation. Main technique of revascularization is presented with highlights of modern mini extracorporeal circulation and beating heart surgery devices. Clinical physiological aspects of the method are described and bibliographical data provided.
Ly Linh G - - 2007
In premature infants, the clinical effects and management of a hemodynamically significant patent ductus arteriosus (HSDA) are well-described. In full-term neonates the ductus arteriosus (DA) is rarely monitored except in cases of concomitant pulmonary hypertension or duct dependent congenital heart disease. Although systemic-pulmonary shunting commonly occurs in mature infants, coinciding ...
Schmitz Thomas - - 2007
BACKGROUND: Chorangiomas are villous capillary tumors of the placenta with high impact on neonatal morbidity and mortality. Cardiac complications have occasionally been reported. OBJECTIVE: To elucidate clinical features, diagnosis and treatment of cardiac failure caused by chorangiomas. METHOD:We report a case of a newborn, in whom massive chorangiomas were associated ...
McManus D - - 2006
Congestive heart failure is a common cardiovascular disorder among adults and is a major cause of morbidity and mortality worldwide. Diastolic heart failure (DHF) is implicated in 1/3 to 1/2 of all heart failure cases and results from an abnormality of ventricular relaxation, compliance or filling. DHF differs from heart ...
Bers Donald M - - 2006
Ca is critical in both the electrical and mechanical properties of cardiac myocytes, and much is known about ionic currents and the normal excitation-contraction coupling process. In heart failure, there are significant alterations in how myocyte Ca is regulated, and these alterations are critical in dictating both contractile dysfunction and ...
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