Search Results
Results 451 - 500 of 923
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Sanderson J E - - 2007
Nearly half of patients with symptoms of heart failure are found to have a normal left ventricular (LV) ejection fraction. This has variously been labelled as diastolic heart failure, heart failure with preserved LV function or heart failure with a normal ejection fraction (HFNEF). As recent studies have shown that ...
Yu Doris S F - - 2006
AIMS: Disease management programmes (DMPs) have evolved as an innovative clinical practice system to enhance the discharge outcomes of older people with heart failure. Yet, clinical trials which have examined their effectiveness have reported inconsistent findings. This may be explained by variations in the design of DMPs. The aim is ...
Pandis Nikolaos - - 2005
The purpose of this study was to assess the long-term in vivo failure rate of tubes bonded to first and second molars with a self-etching primer (SEF). A total of 810 molar tubes (414 first molar and 396 second molar) were bonded on 135 patients (56 male, 79 female; mean ...
Rutten, Frans Hendrik
The main aim of the thesis was to assess the prevalence of heart failure in patients with a diagnosis of chronic obstructive pulmonary disease (COPD). Furthermore, to explore diagnostic strategies (including natriuretic peptides and cardiovascular magnetic resonance imaging (CMR)) to identify heart failure in COPD patients. Finally, to document common ...
Omokhodion S I - - 2005
OBJECTIVES: To evaluate the short term prognosis of childhood heart failure and highlight the factors that affect outcome among cases of heart failure admitted into the paediatric wards, University College Hospital, Ibadan. BACKGROUND: Childhood heart failure remains a major cause of morbidity and mortality in the developing world. The advent ...
Ahmed Ali - - 2005
BACKGROUND: Studies of patients with heart failure and preserved systolic function report variable outcomes compared with those of patients with impaired systolic function. OBJECTIVE: To study outcomes of diastolic (vs systolic) heart failure in older adults with chronic heart failure. METHODS: Patients were ambulatory chronic heart failure patients 65 years ...
Chong Aun Yeong - - 2006
Circulating endothelial cells (CECs) in the peripheral blood, probably representing the most direct evidence of endothelial cell damage, are increased in myocardial infarction, unstable angina and critical limb ischaemia. As chronic heart failure is also associated with endothelial abnormalities, we hypothesised that CECs are raised in acute heart failure and ...
Pitzalis Maria Vittoria - - 2006
Increased circulating levels of endogenous ouabain (EO) have been observed in some heart failure patients, but their long term clinical significance is unknown. This study investigated the prognostic value of EO for worsening heart failure among 140 optimally treated patients (age 50+/-14 years; 104 male; NYHA class 1.9+/-0.7) with idiopathic ...
Gómez-Garre Dulcenombre - - 2006
Peroxisome proliferator-activated receptors (PPARs), key transcriptional regulators of lipid and energy metabolism in cardiomyocytes, have recently been proposed to modulate cardiovascular pathophysiological responses in experimental models. However, there is little information about the functional activity of PPARs in human heart failure. To investigate PPAR-alpha and -gamma expression and activity, and ...
Figulla Hans R - - 2006
In a recent COMET trial (Lancet 362, 2003:7-13) it could be demonstrated that carvedilol < or = 50 mg/d was superior to metoprolol tartrate < or = 100 mg/d in the treatment of heart failure patients NYHA II-IV. It was investigated whether the superiority of carvedilol with its beta1, beta2 ...
Palmer Bradley M - - 2005
Modifications in thick filament protein content and performance are thought to underlie contraction-relaxation dysfunction in human heart failure. It has been found that myofibrillar Mg.ATPase is reduced in failing myocardium, which may be due in part to the reduction in alpha-myosin heavy chain (MHC) isoform content from approximately 5-10% in ...
Goldacre Michael J - - 2005
OBJECTIVE: It is widely held that there will be an epidemic of heart failure in Europe and North America as a result of increased survival from myocardial infarction and other coronary heart disease. The study objective was to discover if the decline in mortality from coronary heart disease has been ...
Katircibasi Mahmut Tuna - - 2005
Heart rate recovery is the difference in heart rate at peak exercise and at a specific time interval following the onset of recovery. Attenuated heart rate recovery is an independent predictor of mortality in patients with a history of coronary artery disease. The aim of the present study was to ...
O'Meara Eileen - - 2006
Glomerular filtration rate (GFR) has major prognostic implications in heart failure. Our objective was to validate the MDRD prediction equations for GFR in patients with advanced heart failure, and to compare their predictive performance to that of the Cockcroft-Gault (CG) equation. We analysed GFR in 45 patients referred for heart ...
Malik M H A - - 2005
We describe the association between immediate post-operative radiological appearances and early aseptic failure of total hip replacement. Sixty-three hips were entered into the aseptic failure group and 138 into the control group. Alignment of the femoral stem was not associated with failure (p=0.283). Thickness of the cement mantle was associated ...
Xiong Wei - - 2005
Spatial electrical heterogeneity has a profound effect on normal cardiac electrophysiology and genesis of cardiac arrhythmias in diseased hearts. The Na+-Ca2+ exchanger (NCX) is a key linker, through Ca2+ signaling, between contractility and arrhythmias. Here we characterize the differential transmural expression of NCX in normal and rapid pacing-induced failing canine ...
Pandis Nikolaos - - 2005
INTRODUCTION: The purpose of this study was to comparatively assess the failure rate of brackets bonded with 2 self-etching adhesives after 14 months of treatment. METHODS: Twenty-two patients with complete permanent dentitions, and similar treatment plans and mechanotherapies, were selected for the study. Four hundred twenty-three brackets were bonded by ...
Goldberg Robert J - - 2005
PURPOSE: Despite often stated references to the emerging epidemic of heart failure in the United States, relatively little data are available describing the incidence and short-term death rates associated with this clinical syndrome. The objectives of this study were to describe the hospital incidence and death rates associated with acute ...
Tayler Michael - - 2005
Doctors often use a range of euphemisms as a means to facilitate communication in the consultation. The present experimental study aimed to assess whether GPs use or avoid the term 'heart failure' and to evaluate the relative impact of the term 'heart failure' versus their preferred euphemism on patients' beliefs ...
Yun Andrew G - - 2005
Although constrained acetabular liners have been successfully used for the treatment of recurrent hip instability, their usage has led to a growing number of associated complications. Twenty-seven patients (29 hips) who experienced failure of the constrained acetabular construct were retrospectively reviewed to define mechanisms of failure. Of these patients, 8 ...
Matthews Kenneth G - - 2005
BACKGROUND: Following myocardial infarction, progressive deterioration of left ventricular function often follows, leading eventually to overt heart failure. In the myocardium, there is increased expression of insulin-like growth factor I (IGF-I) mRNA, protein and receptor levels, particularly in the peri-infarct zone, suggesting that IGF-I has a role to play in ...
Miani Daniela - - 2005
Patients affected by heart failure have a compromised quality of life (QOL) and in the last few years "health related quality of life" has become an important outcome indicator for the evaluation of heart failure treatment. METHODS: Translation into Italian of the Left Ventricular Dysfunction Questionnaire (LVD-36), a new, 36-item, ...
Book Wendy M - - 2005
BACKGROUND: Adult survival is now the rule for most congenital heart defects. However, despite surgical "repair," heart failure remains a common long-term complication of congenital heart disease. Heart failure specialists are seeing an increasing number of patients with congenital defects as the underlying etiology of their heart failure. METHODS AND ...
García Eulogio E Cardiología Intervencionista, Hospital Universitario Gregorio Marañón, Madrid, - - 2005
Percutaneous mechanical reperfusion during acute myocardial infarction with ST-segment elevation has proved to be the most effective way of quickly restoring adequate flow in the affected coronary artery. Randomized clinical trials have shown that percutaneous coronary intervention (PCI) is superior to thrombolysis. Initial fears about the use of stents in ...
Hilfiker-Kleiner Denise - - 2005
The transcription factor signal transducer and activator of transcription 3 (STAT3) participates in a wide variety of physiological processes and directs seemingly contradictory responses, such as proliferation and apoptosis. The constitutive activation of STAT3 promotes tumor growth and angiogenesis and is associated with drug resistance in cancer therapy. In contrast, ...
Forbes Thomas L - - 2005
BACKGROUND: Several studies have reviewed the role of hospital and surgeon case volumes in determining early mortality after elective open abdominal aortic aneurysm (AAA) repair. Few, however, have analyzed this relationship at the individual surgeon level. The purpose of this study was to display the usefulness of a unique statistical ...
Tostes Sebastião S - - 2005
Chagas' disease is caused by the parasite Trypanosoma cruzi. The disease affects 16-18 million patients in South America and heart involvement is the major cause of morbidity and mortality of the disease. The myocarditis observed during the chronic phase affects patients independently of the clinical manifestation, although patients with heart ...
Calvert Melanie J - - 2005
To assess the quality of life of patients with heart failure, due to left ventricular dysfunction (NYHA class III or IV), taking optimal medical therapy using baseline quality of life assessments from the CArdiac REsynchronisation in Heart Failure (CARE-HF) trial, and to evaluate the appropriateness of using the EQ-5D in ...
Ravani Pietro - - 2005
BACKGROUND: Arteriovenous fistulae survive longer than grafts and catheters. However, their short term outcomes may not be as good. We sought to determine whether fistulae created in patients referred to a nephrologist less than 3 months before dialysis start show higher risk of unsuccessful use and early failure. METHODS: All ...
Leier Carl V - - 2005
Aside from cardiac transplantation, ventricular assist devices, and the total artificial heart, cardiac surgery now also plays a major role in the overall management of the heart failure patient. For patients with heart failure, cardiac surgery has steadily moved from being a predominant rescue procedure (eg, aneursymectomy, rupture repair, transplantation) ...
Misiaszek Brian - - 2005
BACKGROUND: Digoxin is often used in long-term care (LTC) residents with heart failure despite a high risk of toxicity associated with increased age, comorbidities and polypharmacy. This toxicity may occur at serum digoxin concentrations that are as low as 1.54 nmol/L. OBJECTIVES: To determine the prevalence of digoxin use, estimate ...
Yturralde R Frederick - - 2005
A diagnosis of diastolic heart failure can be made if the patient exhibits clinical evidence of heart failure and has a normal left ventricular ejection fraction. The diagnosis is confirmed if there is evidence of ventricular hyperthrophy and/or concentric remodeling, left atrial enlargement, or laboratory evidence of diastolic dysfunction.
Herzog Eyal - - 2005
Acute heart failure poses a major healthcare problem. Recent guidelines for heart failure address management of outpatient chronic heart failure but do not address inpatient management. We present a unique, simple, yet comprehensive pathway that focuses on the differential diagnosis of new-onset heart failure and acute decompensation of chronic heart ...
Zile Michael R - - 2005
Patients with chronic heart failure can be divided into 2 broad categories: systolic heart failure and diastolic heart failure. There are significant differences in demographics, prognosis, left ventricular structure, as well as systolic and diastolic function between these 2 groups of patients. The purpose of this presentation is to define ...
Huss Janice M - - 2005
The mitochondrion serves a critical role as a platform for energy transduction, signaling, and cell death pathways relevant to common diseases of the myocardium such as heart failure. This review focuses on the molecular regulatory events and downstream effector pathways involved in mitochondrial energy metabolic derangements known to occur during ...
Anah, MU; College of ...
A study of heart failure among paediatric emergencies in the University of Calabar Teaching Hospital, Calabar, was prospectively carried out over a period of 9 months in the Children's Emergency Room (CHER). Two hundred & thirty four out of 1512 admissions presented with heart failure giving a prevalence of 15.5%. ...
Kuramochi Takahiro - - 2005
In the context of heart failure and myocardial ischemia reperfusion, the activity of the sodium-calcium exchanger can lead to calcium overload, which in turn can lead to contractile dysfunction and arrhythmia. Therefore, NCX is an attractive target for treatment of heart failure and myocardial ischemia reperfusion. We have designed and ...
Kassiri Zamaneh - - 2005
Cardiovascular disease poses a major health care burden in the Western world. Following myocardial injuries, ventricular remodelling and dysfunction ensue, which can eventually culminate in heart failure. An important event in left ventricular (LV) remodelling is alteration of the extracellular matrix (ECM) integrity, the structural network that interconnects the myocardial ...
Hurley Katrina - - 2005
This article reports the case of a 73-year-old man with hypocalcemia-induced heart failure secondary to primary idiopathic hypoparathyroidism. Total calcium at the time of presentation was 5.36 mg/dL (1.34 mmol/L). Ventricular function, as documented by echocardiogram, showed improvement with correction of serum calcium levels. Heart failure is rarely observed in ...
Héliès-Toussaint Cécile - - 2005
Heart failure is a severe pathology, which has displayed a dramatic increase in the occurrence of patients with chronic heart disease in developed countries, as a result of increases in the population's average age and in survival time. This pathology is associated with severe malnutrition, which worsens the prognosis. Although ...
Aldred Hazel - - 2005
AIM: This paper reports a study exploring the impact of advanced heart failure on the lives of older patients and their informal carers. BACKGROUND: Prognosis is poor in heart failure, with more than a third of patients dying within 12 months of diagnosis, and end-of-life symptoms are distressing and poorly ...
Mentula P - - 2005
BACKGROUND: Several biological markers and clinical scoring systems have been used to predict the course of acute pancreatitis. Because organ failure is the most severe complication of the disease, prognostic markers and their combinations that would predict organ failure on hospital admission were sought. METHODS: Some 351 consecutive patients with ...
Karagounis Apostolos P - - 2005
Purulent pericarditis involves the whole pericardium and usually presents as an acute illness with high mortality without prompt diagnosis and treatment. Presentation as a mediastinal mass causing compression of the right ventricle (RV) and symptoms of heart failure in patients without previous cardiac surgery is very rare and only three ...
Whalley Gillian A - - 2005
Echocardiography is an excellent noninvasive tool for the assessment of ventricular size and both systolic and diastolic function, and it is routinely used in patients with heart failure. This review will discuss the role of echocardiography in heart failure diagnosis, prognostic assessment and in the management of heart failure patients.
Turris Mark - - 2005
Heart failure is a complex syndrome with a high morbidity and mortality rate. The Canadian mortality rate is between 25% and 40% annually. End-stage heart failure patients suffer from many debilitating symptoms. Palliative symptom management and funding programs can assist many of these patients. Unfortunately, designating a heart failure patient ...
Yabuuchi Shin-ichi - - 2005
An 82-year-old woman underwent total gastrectomy for advanced gastric cancer with invasion to the lower esophagus. Her blood pressure dropped alarmingly during the operation, which was performed via the transabdominal and left-side transthoracic approach. Using echocardiography, we diagnosed intraoperative-onset reversible heart failure caused by ampulla cardiomyopathy. Because the infusion of ...
Wang Y Z - - 2005
OBJECTIVE: Plasma concentrations of endothelin-1 and big-endothelin are increased in heart failure patients. However, the precise contribution of endothelin secretion from the cardiopulmonary system remains unresolved. The aim of this study was to investigate whether the cardiopulmonary system contributes to the circulating endothelin-1 and big-endothelin concentrations in heart failure patients. ...
Yuen A H Y - - 2005
Possession of the C34T mutation in AMP deaminase (AMPD1) gene has been shown to be associated with attenuation of the progression of heart failure and improved survival in ischemic heart disease. In this study, we examined the frequency of the mutation in the heart with good and poor cardiac function ...
Iyengar Srinivas - - 2005
This is a case of a 21-year-old female with a history of polycystic ovary syndrome who was subsequently diagnosed with heart failure. The patient did not have a family history of heart failure, nor did the patient herself have evidence of ischemic or valvular heart disease or prior viral infection. ...
Goodlin Sarah J - - 2005
Heart failure is the most common reason for hospitalization among older adults in the USA, and impacts five million people. Most people with heart failure are elderly, but in older people the management of the disease is complicated by comorbid conditions. Common problems in the elderly, such as dementia, frailty ...
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