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Results 451 - 500 of 885
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Kassiri Zamaneh - - 2005
Cardiovascular disease poses a major health care burden in the Western world. Following myocardial injuries, ventricular remodelling and dysfunction ensue, which can eventually culminate in heart failure. An important event in left ventricular (LV) remodelling is alteration of the extracellular matrix (ECM) integrity, the structural network that interconnects the myocardial ...
Hurley Katrina - - 2005
This article reports the case of a 73-year-old man with hypocalcemia-induced heart failure secondary to primary idiopathic hypoparathyroidism. Total calcium at the time of presentation was 5.36 mg/dL (1.34 mmol/L). Ventricular function, as documented by echocardiogram, showed improvement with correction of serum calcium levels. Heart failure is rarely observed in ...
Héliès-Toussaint Cécile - - 2005
Heart failure is a severe pathology, which has displayed a dramatic increase in the occurrence of patients with chronic heart disease in developed countries, as a result of increases in the population's average age and in survival time. This pathology is associated with severe malnutrition, which worsens the prognosis. Although ...
Aldred Hazel - - 2005
AIM: This paper reports a study exploring the impact of advanced heart failure on the lives of older patients and their informal carers. BACKGROUND: Prognosis is poor in heart failure, with more than a third of patients dying within 12 months of diagnosis, and end-of-life symptoms are distressing and poorly ...
Mentula P - - 2005
BACKGROUND: Several biological markers and clinical scoring systems have been used to predict the course of acute pancreatitis. Because organ failure is the most severe complication of the disease, prognostic markers and their combinations that would predict organ failure on hospital admission were sought. METHODS: Some 351 consecutive patients with ...
Karagounis Apostolos P - - 2005
Purulent pericarditis involves the whole pericardium and usually presents as an acute illness with high mortality without prompt diagnosis and treatment. Presentation as a mediastinal mass causing compression of the right ventricle (RV) and symptoms of heart failure in patients without previous cardiac surgery is very rare and only three ...
Whalley Gillian A - - 2005
Echocardiography is an excellent noninvasive tool for the assessment of ventricular size and both systolic and diastolic function, and it is routinely used in patients with heart failure. This review will discuss the role of echocardiography in heart failure diagnosis, prognostic assessment and in the management of heart failure patients.
Turris Mark - - 2005
Heart failure is a complex syndrome with a high morbidity and mortality rate. The Canadian mortality rate is between 25% and 40% annually. End-stage heart failure patients suffer from many debilitating symptoms. Palliative symptom management and funding programs can assist many of these patients. Unfortunately, designating a heart failure patient ...
Yabuuchi Shin-ichi - - 2005
An 82-year-old woman underwent total gastrectomy for advanced gastric cancer with invasion to the lower esophagus. Her blood pressure dropped alarmingly during the operation, which was performed via the transabdominal and left-side transthoracic approach. Using echocardiography, we diagnosed intraoperative-onset reversible heart failure caused by ampulla cardiomyopathy. Because the infusion of ...
Wang Y Z - - 2005
OBJECTIVE: Plasma concentrations of endothelin-1 and big-endothelin are increased in heart failure patients. However, the precise contribution of endothelin secretion from the cardiopulmonary system remains unresolved. The aim of this study was to investigate whether the cardiopulmonary system contributes to the circulating endothelin-1 and big-endothelin concentrations in heart failure patients. ...
Yuen A H Y - - 2005
Possession of the C34T mutation in AMP deaminase (AMPD1) gene has been shown to be associated with attenuation of the progression of heart failure and improved survival in ischemic heart disease. In this study, we examined the frequency of the mutation in the heart with good and poor cardiac function ...
Iyengar Srinivas - - 2005
This is a case of a 21-year-old female with a history of polycystic ovary syndrome who was subsequently diagnosed with heart failure. The patient did not have a family history of heart failure, nor did the patient herself have evidence of ischemic or valvular heart disease or prior viral infection. ...
Goodlin Sarah J - - 2005
Heart failure is the most common reason for hospitalization among older adults in the USA, and impacts five million people. Most people with heart failure are elderly, but in older people the management of the disease is complicated by comorbid conditions. Common problems in the elderly, such as dementia, frailty ...
Tsironi M - - 2005
In patients with thalassemia major (TM) who are non-compliant with long-term desferrioxamine (DFO) chelation, survival is limited mainly because of cardiac complications of transfusional hemosiderosis. Combined chelation therapy with DFO and deferiprone has maximized the efficacy of the therapy and reduced cardiological complications. The aim of this report is to ...
Pennell Dudley J - - 2005
Magnetic resonance T2* values of the myocardium are directly related to tissue iron levels. Minor effects from myocardial oxygenation and fibrosis are overwhelmed by the highly dominant iron effect in clinically relevant levels of myocardial iron overload. Myocardial T2* values less than 20 ms indicate iron overload, and this is ...
Foley Robert N - - 2005
The combination of heart failure and chronic kidney disease (CKD) has received comparatively little attention in terms of clinical research versus investigations of each state individually. It has been known for over a decade that anemia, a cardinal feature of CKD, is associated with higher cardiovascular event rates in late-stage ...
Calafiore Antonio Maria AM Division of Cardiac Surgery, University Hospital "S. Giovanni Battista", c.so Bramante 86, Turin, - - 2005
Left ventricular (LV) aneurysm is a complication of an acute myocardial infarction (AMI). Herein a new technique is described that is indicated when the postinfarctual scar involves the septum more than the free wall. The incision starts at the apex and is directed, parallel to LAD, toward the base of ...
Deville Claude C Department of Cardio-Vascular Surgery, Hôpital Haut-Lévêque, avenue de Magellan, 33604 Bordeaux-Pessac, - - 2005
Repair of post-infarction ventricular septal defect (VSD) remains a challenging procedure with a high risk of VSD recurrence. In order to reduce this risk, a double patch and glue technique was introduced in the department in 1986. This surgical technique is hereunder presented. Since 1971, ninety-three patients have been operated ...
Mickleborough Lynda L Department of Surgery, University of Toronto, Toronto, Ontario, - - 2005
A presentation of our approach for ventricular reconstruction or aneurysm resection which includes a modified linear closure plus septal patch technique when indicated. Our philosophy regarding reconstruction combined with coronary artery bypass grafting (CABG) versus revascularization alone is reviewed. When reconstruction is indicated, the surgical approach is planned on the ...
Menicanti Lorenzo L Cardiac Surgery, San Donato Hospital, Via Morandi 30, 20097 San Donato Milanese, - - 2005
Surgical ventricular restoration (SVR) is an emerging technique aiming to restore left ventricular geometry and function in dilated ischemic cardiomyopathy. It applies not only to the classic aneurysm (Type 1) but also to the true ischemic dilated cardiomyopathy (Type 3) and to the intermediate type (Type 2). This type classification ...
Yuen A H Y AH Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middlesex, UB9 6JH, - - 2005
Adenosine (Ado) triggers several protective mechanisms that may attenuate development of heart failure, both locally and systemically. We developed a procedure allowing sustained increase in endogenous Ado production by the combined application of Ado metabolism inhibitors and nucleotide precursors. We found that our procedure attenuate the development of heart failure ...
Garg Shaila - - 2005
Heart failure is the final common pathway of diverse etiologies that are characterized by impaired systolic and/or diastolic function with high morbidity and mortality. An integral part of pathogenesis of heart failure is myocyte loss. The traditional explanation for myocyte loss was cell necrosis but over the last decade, there ...
Dosh Steven A - - 2004
Heart failure is a common, progressive, complex clinical syndrome with high morbidity and mortality. Coronary artery disease is its most common cause. The evaluation of symptomatic patients with suspected heart failure is directed at confirming the diagnosis, determining the cause, identifying concomitant illnesses, establishing the severity of heart failure, and ...
Tsironi Maria - - 2004
Hypocalcemic cardiomyopathy due to primary or secondary hypoparathyroidism is usually refractory to conventional treatment for cardiac failure but responds favorably to the restoration of normocalcemia. We report on a thalassemic patient with severe cardiac failure due to hypocalcemia. Cardiac echocardiography showed impaired biventricular performance and laboratory analyses revealed hypoparathyroidism due ...
Pyle W Glen - - 2004
Cardiac Z-discs have historically been classified as passive myocardial elements. Z-discs are positioned at the junction between the cytoskeleton and the myofilaments, providing a physical connection between the sarcomere, nucleus, membrane and sarcoplasmic reticulum. Moreover, numerous molecular messengers congregate at the Z-disc. The combination of physical and chemical signals moving ...
Hobbs Robert E - - 2004
Heart failure has reached epidemic proportions. Five million Americans have been diagnosed with heart failure, and this number is expected to double within the next 30 years. One million patients are hospitalized annually with decompensated heart failure, and half will be readmitted for recurrent symptoms within 6 months. Heart failure ...
Chinnaiyan Kavitha M - - 2004
This is the case of a patient who presented with severe right-sided heart failure due to diastolic dysfunction that caused a dilemma of differential diagnosis between restrictive cardiomyopathy and constrictive pericarditis. Restrictive cardiomyopathy was diagnosed based on noninvasive and invasive hemodynamic testing. However, the patient did not respond to therapy ...
Spindler M - - 2004
Growth hormone (GH) deficiency decreases left ventricular (LV) contractility, induces LV chamber dilatation and promotes progression to congestive heart failure. It is, however, controversial, whether GH replacement therapy in addition to standard medical heart failure therapy should be considered as routine treatment in GH deficient patients with heart failure. In ...
Avsar Alaettin - - 2004
Hypocalcemia is a rare cause of reversible heart failure. We reported a 40-year-old woman who had severe heart failure resistant to the usual antifailure therapy. She had severe hypocalcemia due to hypoparathyroidism after strumectomy. Echocardiography showed a large left ventricle with very low ejection fraction of 25% and moderate mitral ...
Visser Loes E - - 2004
Heart failure has been identified as a risk factor for increased coumarin anticoagulant responsiveness in several small-scale experiments. Epidemiological studies quantifying the risk of overanticoagulation by heart failure in a non-selected population on coumarins are scarce. Therefore, we investigated whether patients with heart failure have an increased risk of overanticoagulation ...
DeWalt Darren A - - 2004
Development and pilot testing of a disease management program for low literacy patients with heart failure. BACKGROUND: Randomized trials have shown that disease management programs can reduce hospitalizations and improve symptoms for patients with congestive heart failure. We sought to create and pilot test such a program for patients with ...
Fonseca Cândida - - 2004
To validate and estimate the performance statistics and concordance of seven clinical questionnaires for the diagnosis of chronic heart failure (HF). Community-based epidemiological survey of patients aged >25 years attending a random sample of primary health care centers in Portugal. Heart failure was identified according to the Guidelines of the ...
Fonseca Cândida - - 2004
The value of symptoms and signs in the diagnosis of CHF has rarely been tested in large numbers of patients in the community. The aim of this study was to evaluate the importance of symptoms, signs, and past medical history in the diagnosis of CHF in primary care. Data on ...
Fonseca Cândida - - 2004
There is a common assumption that a normal ECG or a normal heart size on chest X-ray virtually rules out a diagnosis of heart failure. To assess the value of the electrocardiogram and chest X-ray in identifying patients with chronic heart failure in the community. This study was a secondary ...
Mallat Ziad - - 2004
Interleukin (IL)-18 is the interferon-gamma-inducing factor and has potent proinflammatory activities. IL-18 has been recently implicated in atherosclerotic plaque instability and myocardial ischemia-reperfusion injury. However, it is unknown whether IL-18 expression is increased in human myocardium or if it has any role in heart failure. We analyzed the expression of ...
Tendera Michal - - 2004
Heart failure is becoming increasingly common. More than 20 million people worldwide are estimated to have heart failure. Prevalence is rising because the population is ageing: in both men and women, the prevalence of heart failure in those aged 80-89 years is roughly 10 times the prevalence in those aged ...
Taylor Anne L - - 2004
Despite ethnic differences in heart failure prevalence, risk profiles, and outcomes, no clinical trials have been designed to prospectively examine the mechanisms responsible for these differences. The African-American Heart Failure Trial is the first prospective trial designed to test a novel therapy that enhances endothelial function and nitric oxide bioavailability ...
Khunti K - - 2004
The aim of this study was to examine the usefulness of 12-lead electrocardiogram in screening patients with suspected heart failure for open access echocardiography. We carried out a systematic review and meta-analysis of published observational studies. Published studies were identified in the Medline and Embase databases, this was supplemented by ...
Garrett P M - - 2004
Acute right heart failure in a young person is an unusual presentation and drug overdose is a rare cause. A case is described where the patient presented with striking clinical signs of acute pulmonary hypertension and right heart failure, which were confirmed by transthoracic echocardiography. The precipitating event appeared to ...
Heckman George A - - 2004
BACKGROUND: In long-term care (LTC) facilities, heart failure is common but undertreated. No Canadian studies of heart failure in LTC facilities have been reported. OBJECTIVES: To estimate the prevalence of heart failure in Canadian LTC facilities; to document the management of heart failure in LTC; and to describe characteristics of ...
Soto Gabriel E GE Washington University School of Medicine, St Louis, Mo, - - 2004
Disease-specific health status instruments such as the Kansas City Cardiomyopathy Questionnaire (KCCQ) can quantify symptoms, functional limitations, and quality of life in patients with heart failure. Understanding the relationship between KCCQ scores and prognosis may assist clinicians in both interpreting KCCQ scores and stratifying risk in patients. We examined the ...
Saran Rajiv - - 2004
BACKGROUND: Optimal waiting time before first use of vascular access is not known. METHODS: Two practices-first cannulation time for fistulae and grafts, and blood flow rate-were examined as potential predictors of vascular access failure in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Access failure (defined as time to first ...
Peacock W Franklin WF - - 2004
The Acute Decompensated HEart Failure National REgistry (ADHERE(R)) confirms that the management of decompensated heart failure is an emergency department (ED) problem, as more than 75% of patients admitted to the hospital with heart failure arrive through the ED. This emphasizes the need for collaboration among emergency medicine, cardiology, nephrology, ...
Shah S - - 2004
To evaluate the role of an open access heart failure service based at a teaching hospital for the diagnosis and treatment optimisation of patients with heart failure in the community and to identify measures that may further enhance the effectiveness of such a service. 963 patients with suspected heart failure ...
Sommerville R S - - 2004
An acute cardiac tamponade from any cause may result in rapid deterioration of hepatic function in a previously healthy patient. We describe a case of an acute ascending aortic dissection that presented as acute hepatic failure, due to an acute cardiac tamponade and severe right heart failure. The differential diagnosis ...
Nummenmaa Lauri - - 2004
Meta-analytic techniques were used to assess whether successes and failures can be used experimentally to induce affective states. Data from 32 studies, with a total of 2,468 participants, were reviewed. Methods for producing success-failure experiences, as well as the resulting affective reactions, were analyzed. Effect sizes as a result of ...
Raftopoulos S C - - 2004
Levosimendan is a novel inotropic agent indicated for patients with decompensated heart failure. It has well recognised mechanisms of action. Its use however, has not been described in patients with end-stage renal failure. This report describes the use of levosimendan in a post-operative coronary artery bypass graft patient with decompensated ...
Di Somma S - - 2004
Our aim was to evaluate the desmin content in the myocardial tissue of patients with end-stage heart failure of ischaemic origin and to assess its role on cardiac function. We studied 18 explanted hearts from patients transplanted for end-stage heart failure due to ischaemic cardiomyopathy (ICM). Control myocardial tissue was ...
Yacoub Magdi H MH Heart Science Centre, Imperial College at Harefield Hospital, Harefield, Middx UB9 6JH, UK. - - 2004
Dysfunction of the donor heart is an important clinical problem that could be affected by genetic factors. We tested the hypothesis that possession of the C34T nonsense mutation in AMPD1 gene, which is known to improve survival in chronic heart failure, protects against cardiac dysfunction in donors. Genetic analysis for ...
Twickler Th B - - 2004
Cardiomyopathy is a major cause of death in overt acromegaly. Recent progress in research has increasingly revealed the molecular mechanisms concerning growth hormone and insulin-like growth factor in the development of heart failure. In this article, we propose mechanisms according to which heart failure occurs, and we aim to extrapolate ...
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