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Results 251 - 300 of 2211
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Ducas R A - - 2011
Arsenic trioxide has become the treatment of choice for patients with acute promyelocytic leukaemia. Cardiovascular toxicity is known to occur with this therapy, in particular heart rhythm disorders due to QT interval prolongation. We present a case of ventricular arrhythmia with no QT prolongation in a patient receiving arsenic trioxide ...
El-Armouche Ali - - 2011
Follistatin-like 1 (FSTL1) is an extracellular glycoprotein found in human serum. Recent work suggests that FSTL1 is secreted in response to ischemic injuries and that its overexpression is protective in the heart and vasculature. We examined serum FSTL1 levels in patients with chronic heart failure with left ventricular (LV) ejection ...
Su Mao-Yuan M - - 2011
PURPOSE: To study the effect of exercise training on the myocardial perfusion in the postinfarct myocardium. MATERIALS AND METHODS: Twenty-nine patients with stable chronic myocardial infarction were randomly assigned to either a training group (N = 17) or a control group (N = 12). The training group received a 3-month ...
Gauna A - - 2011
Background: How the duration of hypothyroidism affects left ventricular diastolic function is not well-characterized. Aim: We sought to compare left ventricular diastolic function in acutely vs. chronically hypothyroid patients vs. euthyroid controls, and within individuals while on vs. off T4. Subjects and Methods: We prospectively performed such comparisons measuring pulsed-wave ...
Tang W H Wilson - - 2011
Galectin-3 plays an important role in fibroblast activation and fibrosis in animal models. Increased galectin-3 levels are associated with poor long-term survival in heart failure (HF). We examined the relation between plasma galectin-3 levels and myocardial indexes of systolic HF. We measured plasma galectin-3 in 133 subjects with chronic HF ...
Dini Frank Lloyd - - 2011
Many descriptors of left ventricular (LV) remodeling have important prognostic implications in patients with chronic systolic heart failure (HF). We sought to assess the prognostic value of the combination of increased LV mass with a disproportion between wall thickness and internal diameter. Patients (n = 536) with chronic HF, ejection ...
Cubbon Richard M RM University of Leeds, Leeds, United - - 2011
Therapies for patients with chronic heart failure caused by left ventricular systolic dysfunction have advanced substantially over recent decades. The cumulative effect of these therapies on mortality, mode of death, symptoms, and clinical characteristics has yet to be defined. This study was a comparison of 2 prospective cohort studies of ...
Bin Salih Salih A - - 2011
To report on the clinical presentation, etiology, and laboratory features of acute and chronic atrial fibrillation (AF) in a tertiary hospital in Riyadh, Saudi Arabia. We retrospectively studied records of 720 patients with AF seen in outpatients and inpatients departments at King Abdulaziz Medical City, Riyadh, during the period of ...
Burns Kevin V - - 2011
Chronic right ventricular pacing may lead to left ventricular dyssynchrony, systolic dysfunction, remodeling, and heart failure. Cardiac mechanics may differ between paced and nonpaced heart failure patients, and their optimal treatment may also differ. Echocardiograms were analyzed using tissue Doppler imaging and speckle tracking echocardiography in 20 patients with chronic ...
White Harvey D - - 2011
PURPOSE OF REVIEW: To define why a standardized bleeding definition is required and discuss the merits of the Bleeding Academic Research Consortium (BARC) definitions. RECENT FINDINGS: In acute coronary syndromes, bleeding is related to increased mortality, myocardial infarction, and stroke. As newer antiplatelet and antithrombotic agents are developed for the ...
Sibille Louis - - 2011
Gated blood-pool single-photon emission computed tomography (GBPS) was compared with cardiac magnetic resonance (CMR) for the measurement of left ventricular (LV) and right ventricular (RV) ejection fractions (EF) and volumes [end-diastolic volume (EDV) or end-systolic volume (ESV)] in a mixed population. Thirty patients (70% men; mean age: 61±14 years) referred ...
Von Lueder Thomas G - - 2011
In this article, we report on a patient with chronic and modestly elevated plasma troponin T (TnT) levels and frequent hospitalizations following the first admission until his death one year later. The patient was initially admitted for dyspnea and discharged from hospital with a diagnosis of non-ST elevation acute myocardial ...
Goh Ching Yan - - 2011
Over the last decade, it has become increasingly clear that the cardiovascular and renal systems are interdependent. Primary disorders of either system have been shown to disturb the other system. As a result, a class of cardiorenal syndrome (CRS) has been identified where in a vicious cycle is established in ...
House Andrew A - - 2011
Type 4 cardiorenal syndrome is a growing societal problem as the aging population, with increasing incidence of chronic kidney disease (CKD), diabetes, obesity, hypertension, and other cardiovascular risks, leads to higher numbers of individuals suffering the complications of this bidirectional disorder. In this review, the immense burden of cardiovascular risk ...
Przybyła Anna - - 2011
The aim of the study was to assess the influence of cardiac resynchronization therapy(CRT) on a series of humoral parameters crucial for the pathophysiology of chronic heart failure such as aldosterone or the inflammatory markers. Thirty eight consecutive patients (aged 66.3 +/- 9.6 years, 31 men - 82% ) with ...
Voeller Rochus K - - 2011
: Over recent years, a variety of energy sources, including bipolar radiofrequency, have been used to replace the traditional incisions of the Cox-Maze procedure for the surgical treatment of atrial fibrillation (AF). The purpose of this study was to evaluate the safety and efficacy of a novel dual-electrode bipolar radiofrequency ...
Smart Neil A - - 2011
Bucindolol is a non-selective β-adrenergic receptor blocker with α-1 blocker properties and mild intrinsic sympatholytic activity. The Beta-Blocker Evaluation of Survival Trial (BEST), which is the largest clinical trial of bucindolol in patients with heart failure, was terminated prematurely and failed to show an overall mortality benefit. However, benefits on ...
Wang Wen - - 2011
Coronary artery disease and ischemic heart disease are leading causes of heart failure and death. Reduced blood flow to heart tissue leads to decreased heart function and symptoms of heart failure. Therapies to improve heart function in chronic coronary artery disease are important to identify. HMG-CoA reductase inhibitors (statins) are ...
Correale Michele - - 2011
A limited number of studies have used Tissue Doppler Imaging (TDI) to evaluate the effect of statin therapy on left ventricular dysfunction in patients with chronic heart failure. In this work, we aimed to determine whether statin administration influenced prognosis, inflammatory activation and myocardial performance evaluated by Tissue Doppler Imaging ...
Yilmaz Kadir - - 2011
A young man presented with a chronic abdominal dermal irritation 4 years after implantation of a left ventricular assist device (LVAD; Berlin heart excor). The LVAD was needed because of end-stage heart failure following a chronic parvovirus B19 Infection. The implantation of mechanical circulatory support systems (MCS) has nowadays become ...
Ma Li - - 2010
To investigate whether baseline apparent diffusion coefficient (ADC) maps can be employed to predict both infarct core and salvageable ischemic tissue volumes in acute ischemic stroke. An automated image analysis system based on baseline ADC maps was tested against 30 patients with acute ischemic stroke of anterior circulation to predict ...
Hallén Jonas - - 2010
To investigate the ability of cardiac troponin I (cTnI) to predict functional recovery and left ventricular remodelling following primary percutaneous coronary intervention (pPCI) in ST-elevation myocardial infarction (STEMI). Post hoc study extending from randomised controlled trial. 132 patients with STEMI receiving pPCI. Left ventricular ejection fraction (LVEF), end-diastolic and end-systolic ...
Boyd Anita C - - 2010
Changes in left atrial (LA) volumes after ST elevation myocardial infarction are reported but have not been well described following non-ST elevation myocardial infarction (NSTEMI). Seventy-five patients with NSTEMIs were studied within 48 hours of presentation and in follow-up at 6 and 12 months; they were compared with age-matched normal ...
Rossato Luciana Grazziotin - - 2011
Synephrine is cited as 'the active component' of plants and dietary supplements used in weight loss. It became one of the most popular stimulants present in weight-loss products after the US Food and Drug Administration had interdicted the use of ephedrine-containing dietary supplements. Synephrine is also a trace amine that ...
Kuwahara Michio - - 2011
Anemia is a common complication of patients with chronic kidney disease (CKD), which not only lowers their quality of life but also potentially causes cardiovascular diseases such as congestive heart failure and coronary heart disease, and accelerates the progression of renal dysfunction. Pre-dialysis patients were assigned to groups A, B, ...
Aljaroudi W - - 2011
Left ventricular (LV) ejection fraction (EF) and perfusion defect size (PDS) provide independent and incremental prognostic information in patients with coronary artery disease (CAD). The purpose of this study was to examine the correlation between EF and PDS. LVEF and PDS were measured in 96 consecutive patients with CAD and ...
Adhyapak Srilakshmi M - - 2011
Surgical ventricular restoration has been the bailout therapy for end-stage heart failure due to ischemic cardiomyopathy in patients not suitable for cardiac transplantation. The recently concluded STICH trial has stated that surgical restoration of the left ventricle does not benefit this subgroup of patients clinically as compared with revascularization alone. ...
Mori Mika - - 2011
Atrial fibrillation is commonly associated with impaired reservoir and booster functions of the left atrium (LA). Recent advances in two-dimensional speckle tracking technique (2DST) enabled automatic analysis of the time-LA volume curve representing these functions. Our objective was to evaluate LA function in patients with or without paroxysmal atrial fibrillation ...
Alpendurada Francisco - - 2010
Marfan syndrome (MFS) is an inherited connective tissue disease which frequently involves the cardiovascular system. The heart can be affected since valvular regurgitation is a common complication. However, there is still debate whether a primary cardiomyopathy exists. Our aim was to evaluate the existence of a Marfan-related cardiomyopathy using cardiovascular ...
Shahgaldi Kambiz - - 2010
The aim of the study was to investigate whether left ventricular stroke volume (LVSV) assessment using direct measurement of left ventricular outflow tract area (LVOT(A)) is superior to conventional methods for SV calculation. Thirty patients were included in the study (39 ± 12 years). LVSV was assessed by multiplying LVOT ...
Tereshchenko Larisa G - - 2010
Methodological difficulties associated with QT measurements prompt the search for new electrocardiographic markers of repolarization heterogeneity. We hypothesized that beat-to-beat 3-dimensional vectorcardiogram variability predicts ventricular arrhythmia (VA) in patients with structural heart disease, left ventricular systolic dysfunction, and implanted implantable cardioverter-defibrillators (ICDs). Baseline orthogonal electrocardiograms were recorded in 414 patients ...
Broberg Craig S - - 2010
the etiology of ventricular dysfunction in adult congenital heart disease (ACHD) is not well understood. Diffuse fibrosis is a likely common final pathway and is quantifiable using MRI. patients with ACHD (n=50) were studied with cardiac MRI to quantify systemic ventricular volume and function and diffuse fibrosis. The fibrosis index ...
Wilson Helen E - - 2010
Anaemia induces haemodynamic compensatory mechanisms resulting in volume overload and increased left heart dimensions in humans and dogs. The aims of this retrospective study were to investigate the effects of anaemia on echocardiographic left heart dimensions, vertebral heart size (VHS) and radiographic evidence of congestive heart failure (CHF) in cats. Fifteen cats ...
Cowie B S - - 2010
Ultrasound applications in perioperative medicine have expanded enormously over the past decade. Transoesophageal echocardiography has been performed by anaesthetists during cardiac surgery for over 20 years. With the increasing availability of portable ultrasound systems, the use of ultrasound to assist in vascular cannulation and regional anaesthesia has been well described. ...
Singh Raveen - - 2010
The deleterious effects of anesthetic agents in patients suffering from coronary artery disease are well known. The risk increases when a patient has compromised ventricular function. There is a paucity of literature regarding the choice of the suitable agent to avoid deleterious effects in such patients. The use of etomidate ...
Chang Xiao-Rong - - 2010
The effect of acupuncture at the acupoints of 12 meridians on gastrointestinal and cardiac electricity in healthy adults was studied. Specific regulation between meridian points and viscera was also investigated. An electrogastrogram (EGG), electrointestinogram (EIG), carotid pulse graph, phonocardiogram and electrocardiogram were obtained in 30 healthy adults before and after ...
Scharf Michael - - 2010
PURPOSE: To assess cardiac morphologic and functional adaptations in elite triathletes with magnetic resonance (MR) imaging and to compare findings to those in recreationally active control subjects. MATERIALS AND METHODS: The institutional review board approved the study, and written informed consent was obtained from all subjects. Twenty-six male triathletes (mean ...
Chouliaras Giorgos L - - 2010
Cardiac Magnetic Resonance (CMR) has replaced all other surrogate measurements in the determination of transfusional cardiac iron overload in patients with thalassaemia major. We aimed to determine the diagnostic value of CMR T2* with respect to cardiac dysfunction (CD) as determined by CMR-derived left ventricular ejection fraction (LVEF). Cardiac T2* ...
Ugander Martin - - 2010
PURPOSE: To prospectively evaluate the usefulness of magnetic resonance (MR) imaging for estimating pulmonary blood volume (PBV) and the variation in PBV throughout the cardiac cycle in experimental heart failure. MATERIALS AND METHODS: The animal care committee approved this prospective study. Seven pigs were studied before and after myocardial infarction. ...
Reant Patricia - - 2010
Conventionally, the evaluation of left ventricular (LV) systolic function is based on ejection fraction assessment, which may be supplemented by other echocardiographic techniques, such as tissue Doppler imaging, 3D evaluation, and speckle tracking strains. However, these imaging modalities have a high technicity and are time-consuming, while being associated with reproducibility ...
Bauer Axel - - 2010
Assessment of spontaneous baroreflex sensitivity (BRS), an index of autonomic function, poses practical challenges. In this pilot study, we propose a novel technique for assessment of spontaneous BRS based on bivariate phase-rectified signal averaging (PRSA). This is an extension of the monovariate PRSA technology used for calculation of deceleration capacity. ...
Vural Murat - - 2010
To compare multidetector computed tomography (MDCT) and two-dimensional transthoracic echocardiography (2DE) for left ventricular ejection fraction (EF); and to make comparison between reconstructions of 1-mm and 2-mm slice thickness at MDCT in left ventricular analysis by using a semiautomated segmentation algorithm. In 43 patients global left ventricular systolic function was ...
Herberg U - - 2011
The aim of this study was to assess the feasibility, accuracy and reliability of 3D real-time echocardiography for fetal heart volumetry. Fifty unselected and consecutive fetuses, including 14 with cardiac malformations, were scanned prospectively using real-time 3D matrix technology and 2D echocardiography to determine ventricular volumes. Small phantoms as well ...
Wachtell Kristian - - 2010
Endocardial fractional shortening (EFS) and midwall shortening (MWS) are impaired in patients with left ventricular hypertrophy. However, it remains unknown whether improvement of left ventricular systolic function during treatment reduces cardiovascular morbidity and mortality in hypertensive patients with preserved left ventricular function. Echocardiograms were performed yearly in 840 hypertensive patients ...
Filizcan Uğur - - 2010
Left ventricular (LV) pseudoaneurysm is a rare complication of myocardial infarction. It may also occur as a complication of mitral valve surgery, chest trauma, and bacterial endocarditis. It forms when a cardiac rupture contains adherent pericardium or scar tissue and is typically located on the posterior or inferior LV wall. ...
Guo Shi-Zun - - 2010
Granulocyte colony-stimulating factor (G-CSF) seems to improve cardiac function and perfusion when used systemically through mobilization of stem cells into peripheral blood, but results of previous clinical trials remain controversial. This study was designed to investigate safety and efficacy of subcutaneous injection of G-CSF on left ventricular function in patients ...
Heidary Shahriar - - 2010
OBJECTIVES: This study evaluates how characterization of tissue heterogeneity of myocardial infarction by cardiovascular magnetic resonance (CMR) is associated with cardiovascular events (CVE) in patients with ischemic cardiomyopathy (ICM). BACKGROUND: Prior studies demonstrated that the quantification of myocardial scar volume by CMR is superior to left ventricular end-diastolic volume, left ...
Kazui Toshinobu - - 2011
We performed echocardiographic tissue tracking to investigate whether mitral valve repair preserves left ventricular function. We studied 16 subjects without heart disease (11 male; mean age, 54.6 ± 15.1 years) and 18 patients in normal sinus rhythm undergoing solitary mitral valve repair (12 male; mean age, 53.6 ± 16.6 years). Transthoracic echocardiography ...
Babbs Charles F - - 2010
The conventional impedance cardiogram is a record of pulsatile changes in the electrical impedance of the chest with each heartbeat. The signal seems intuitively related to cardiac stroke volume. However doubts persist about the validity of stroke volume measurements based on electrical impedance. This paper presents a new electrical axis ...
Animasahun B A - - 2010
BACKGROUND: Few studies documenting the echocardiographic findings of patients with sickle cell anaemia have been reported from Africa despite the high prevalence of the disease on the continent. AIMS AND OBJECTIVES: The present study aimed to determine echocardiographic cardiac dimensions and haemodynamic parameters of children with homozygous sickle cell anaemia ...
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