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Kamiura Nozomu - - 2013
In patients on dialysis, the most common cause of death is cardiovascular disease. This is caused, at least in part, by excessive vascular calcification. Studies that have examined coronary calcification have been published, but these measurements require expensive equipment. Here, we used computed tomography to determine aortic calcification and evaluated ...
Bartel Thomas T Department of Internal Medicine III, Cardiology Division, Innsbruck Medical University, - - 2013
In aortic stenosis (AS), altered functional capacity may be not only a result of impaired systolic performance but likewise of diastolic left ventricular (LV) dysfunction. In asymptomatic severe AS, in borderline severe AS and in low flow, low gradient AS with reduced ejection fraction (EF), assessment of systolic and diastolic ...
Quick Silvio S Dept. of Cardiology, Heart Centre, University Hospital Dresden, Dresden, Germany. - - 2013
While impact of surgical aortic valve replacement (SAVR) on the function of the right and left ventricle (RV, LV) has been studied extensively, the objective of this study was to compare the two different transcatheter approaches, transfemoral vs. transapical aortic valve implantation (tf-AVI, ta-AVI) and SAVR with respect to postoperative ...
Zheng Ziyu Z Department of Emergency Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, PR - - 2013
Acute myocardial infarction (AMI) concomitant with aortic dissection (AD) is rare but a devastating situation if misdiagnosed as simply AMI, followed by anticoagulant or thrombolytic therapy. In such cases, Standford type B AD was extremely infrequent. To present a case with apparent concordance with the patient's history, symptoms, cardiac enzymes ...
Tresoldi Silvia - - 2013
There is a significant association between aortic atherosclerosis and previous major cardiovascular events. Particularly, thoracic aortic atherosclerosis is closely related to the degree of coronary and carotid artery disease. Thus, there is a rationale for screening the thoracic aorta in patients who undergo a chest computed tomography (CT) for any ...
Shiono Yasutsugu - - 2013
Objectives: The aim of this study was to investigate the impact of myocardial area supplied by the coronary artery on fractional flow reserve (FFR). Background: Various factors other than the degree of epicardial stenosis influence the physiological significance of a coronary artery stenosis. Methods: A total of 296 coronary lesions ...
Toganel Rodica - - 2013
We report the case of a newborn with an aneurysmal aorto-left ventricular tunnel causing significant paravalvular aortic regurgitation and obstruction of the right ventricular outflow tract (RVOT), coexisting with a bicuspid aortic valve. The coexistence of the two malformations together with the obstruction of the RVOT is very rare. In ...
Park Jin-Sun JS Department of Cardiology, Ajou University School of Medicine, Suwon, - - 2013
We report a rare case of thrombus formation in normal aorta causing myocardial infarction. A 44-year-old man who had no prothrombotic risk factors presented with acute myocardial infarction. Two-dimensional echocardiography revealed a hypoechoic homogenous mass occupying the left coronary sinus and attached at the nonatherosclerotic aorta. The mass seemed to ...
Nigro G - - 2013
Sudden death is a possible occurrence for newborns younger than 1 year with severe aortic coarctation (CoA) before surgical correction. In our previous study, we showed a significant increase of QTc-D and JTc-D in newborns with isolated severe aortic coarctation, electrocardiographic parameters that clinical and experimental studies have suggested could ...
Rimehaug Audun E AE Department of Circulation and Medical Imaging, Norwegian University of Science and Technology Trondheim, Norway ; Clinic of Anesthesiology and Intensive Care, Trondheim University Hospital Trondheim, - - 2013
Cardiac power (PWR) is the continuous product of flow and pressure in the proximal aorta. Our aim was to validate the PWR integral as a marker of left ventricular energy transfer to the aorta, by comparing it to stroke work (SW) under multiple different loading and contractility conditions in subjects ...
Min James K JK Department of Radiology, Weill Cornell Medical College and The NewYork-Presbyterian Hospital, New York, NY, USA. Electronic address: - - 2014
Coronary artery disease (CAD) diagnosis by coronary computed tomographic angiography (CCTA) is useful for identification of symptomatic diabetic individuals at heightened risk for death. Whether CCTA-detected CAD enables improved risk assessment of asymptomatic diabetic individuals beyond clinical risk factors and coronary artery calcium scoring (CACS) remains unexplored. From a prospective ...
Iwama Makoto - - 2013
Integrated backscatter intravascular ultrasound (IB-IVUS) is a useful method for analyzing coronary plaque tissue. We evaluated whether tissue composition determined using IB-IVUS is associated with the progression of stenosis in coronary angiography. Sixty-three nontarget coronary lesions in 63 patients with stable angina were evaluated using conventional IVUS and IB-IVUS. IB-IVUS ...
Schwarz Florian - - 2013
This study sought to compare dynamic versus single-phase high-pitch computed tomography (CT) acquisitions for the assessment of myocardial perfusion in a porcine model with adjustable degrees of coronary stenosis. The incremental value of the 2 different approaches to CT-based myocardial perfusion imaging remains unclear. Country pigs received stent implantation in ...
Parikh Ravikumar - - 2013
Objective: To assess myocardial function in preterm infants with different degrees of ductal patency in the first week of life using tissue Doppler imaging. Study design: Infants <30 weeks of gestation underwent echocardiography on day 3. A total of 72 infants were recruited into the study and categorised into three ...
Barone-Rochette Gilles - - 2013
-Recent works using echocardiography suggested that low gradient (LG), low flow (LF) aortic stenosis (AS) has more pronounced LV concentric remodeling, smaller LV cavity size, and more interstitial fibrosis than high gradient (HG) normal flow (NF) AS. Therefore we evaluated the accuracy of echocardiographic measurements, and compared remodeling and fibrosis ...
McDonnell Kelly - - 2013
Ablation of ventricular tachycardia (VT) and premature ventricular contraction (PVC) arising at the aortic root has been described.  The use of radiofrequency ablation energy has been associated with life-threatening collateral damage. The use of cryo-ablation as a safer alternative energy source at the aortic root has not been previously described. ...
Hu Chunfeng - - 2013
This study aimed to evaluate the correlation between coronary stenosis and left ventricular function using dual-source computed tomography (DSCT). DSCT coronary angiography (CAG) was performed on 66 patients with coronary disease and 36 healthy volunteers. The degree of coronary stenosis, end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection ...
Bok Soo-Kyung - - 2013
The mobile thrombus in the aortic arch is a rare condition, which becomes rarer when associated with cerebral infarction, resulting in disabling complications. Transesophageal echocardiography is useful for detecting the source of thrombi in the heart and aortic arch. Here, we report a case of a patient who suffered from ...
Spethmann Sebastian - - 2013
Transcatheter aortic valve implantation (TAVI) has been shown to improve prognosis of high-risk patients. Data, however, concerning the impact of TAVI on regional and global left atrial (LA) and left ventricular (LV) mechanics in varying entities of severe aortic stenosis (AS) are sparse, particularly in patients with paradoxical low-flow (PLF) ...
Driscoll David J - - 2013
Congenital heart defects can be classified as those characterized by a left to right shunt, a right to left shunt, obstruction to flow from the heart, or abnormalcies of myocardial contraction and relaxation. Left to right shunts include atrial and ventricular septal defects, and patent ductus arteriosus. Right to left ...
Chaurasia Amit Kumar AK Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, - - 2013
Coronary embolisation, spontaneous coronary artery dissection, and myocardial bridges are rare causes of Myocardial Infarction (MI) in the youth. Here, we report a young male who developed myocardial infarction at the age of 19. Investigations revealed that he had mitral stenosis, myocardial bridge, and angiographic features of healed coronary dissection.
Korita Irena - - 2013
Inflammation processes are considered important links between classical lipid risk factors and the progression of atherosclerosis. The interrelationship of high density lipoproteins (HDL) and apolipoprotein apoA-1 with acute phase proteins and cytokines was examined in a clinical setting of patients with angina pectoris. On exclusion criteria (myocardial infarction, heart failure, ...
Segura Ana M - - 2013
Continuous-flow left ventricular assist devices (LVADs) provide durable, reliable, energy-efficient long-term support. However, the biologic effects of continuous flow are not completely known. Therefore, we examined aortic wall morphology in patients with heart failure before and after prolonged circulatory support with a continuous-flow LVAD. After applying a partial aortic occlusion ...
Wang Baojun - - 2013
The aim of this study was to investigate the correlation between aortic/carotid atherosclerotic plaques and cerebral infarction. We examined 116 cases of cerebral infarction using transcranial Doppler ultrasound in order to exclude cerebrovascular stenosis. Transesophageal echocardiography and color Doppler ultrasound were used to detect aortic atherosclerotic plaques (AAPs) and carotid ...
García Raquel R Instituto de Formación e Investigación Marqués de - - 2013
Myocardial microRNA-133a (miR-133a) is directly related to reverse remodeling after pressure overload release in aortic stenosis patients. Herein, we assessed the significance of plasma miR-133a as an accessible biomarker with prognostic value in predicting the reversibility potential of LV hypertrophy after aortic valve replacement (AVR) in these patients. The expressions ...
Lee Hsin-Fu - - 2013
Impaired left ventricular (LV) strain is associated with an increased risk of cardiac events in asymptomatic severe aortic stenosis (AS). We aimed to evaluate the prognostic value of global LV strain in conservatively treated patients with symptomatic AS. This cohort study retrospectively reviewed symptomatic AS patients who were treated conservatively ...
D'Ascenzi Flavio - - 2013
Aortic stenosis (AS) results in several left ventricular (LV) disturbances as well as progressive left atrial (LA) enlargement and dysfunction. Transcatheter aortic valve implantation (TAVI) reverses LV remodelling and improves overall systolic function but its effect on LA function remains undetermined. The aim of this prospective, longitudinal study was to ...
Onorati Francesco - - 2013
Despite the widespread use of transcatheter aortic valve implantation (TAVI), the role of sex on outcome after TAVI or surgical aortic valve replacement (AVR) has been poorly investigated. We investigated the impact of sex on outcome after TAVI or AVR. There were 2108 patients undergoing TAVI or AVR who were ...
Caetano Francisca - - 2013
Acute heart failure in patients with severe aortic stenosis and left ventricular systolic dysfunction is well known for its dire prognosis and limited therapeutic options. The authors describe the case of a man admitted for non-ST-elevation myocardial infarction. Diagnostic exams revealed severe aortic stenosis, with good left ventricular systolic function, ...
Lindman Brian R BR Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, - - 2013
Calcific aortic stenosis is a progressive disease with no effective medical therapy that ultimately requires aortic valve replacement (AVR) for severe valve obstruction. Echocardiography is the primary diagnostic approach to define valve anatomy, measure aortic stenosis severity, and evaluate the left ventricular response to chronic pressure overload. In asymptomatic patients, ...
Chen Peter C - - 2013
Left ventricular outflow tract obstruction after neonatal repair of interrupted aortic arch with ventricular septal defect may warrant reintervention. We sought to identify clinical and preoperative echocardiographic predictors of reintervention for postoperative left ventricular outflow tract obstruction. Retrospective data were collected on neonates with interrupted aortic arch with ventricular septal defect ...
Walters Andrew M AM Division of Cardiac Surgery, Strong Memorial Hospital, Rochester, New - - 2013
Providing unobstructed systemic blood flow is one goal of stage I palliation for hypoplastic left heart syndrome. Although clinically significant obstruction is defined when the arch gradient exceeds 15 mm Hg, any positive gradient constitutes obstruction, which may impair ventricular function. We sought to identify risk factors before stage I ...
Didie Michael - - 2013
Total mechanical unloading of the heart in classical models of heterotopic heart transplantation leads to cardiac atrophy and functional deterioration. In contrast, partial unloading of failing human hearts with left ventricular assist devices (LVADs) can in some patients ameliorate heart failure symptoms. Here we tested in heterotopic rat heart transplant ...
Fairbairn Timothy A - - 2013
OBJECTIVE: To compare the effects of transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) on aortic valve haemodynamics, ventricular reverse remodelling and myocardial fibrosis (MF) by cardiovascular magnetic resonance (CMR) imaging. DESIGN: A 1.5 T CMR scan was performed preoperatively and 6 months postoperatively. SETTING: University hospitals ...
La Manna Alessio - - 2013
BACKGROUND: In patients with severe aortic stenosis, left ventricular hypertrophy is associated with increased myocardial stiffness and dysfunction linked to cardiac morbidity and mortality. We aimed at systematically investigating the degree of left ventricular mass regression and changes in left ventricular function six months after transcatheter aortic valve implantation (TAVI) ...
Ben-Dor Itsik - - 2013
Brain natriuretic peptide (BNP) is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients. The present study aimed to assess the relationship of BNP with aortic stenosis (AS) severity and prognosis. The cohort comprised 289 high-risk patients with severe AS who were ...
Alpsoy Seref - - 2013
OBJECTIVE: Prehypertension is one of the primary causes of major cardiovascular events independent from other cardiovascular risk factors. The aim of the study was to evaluate the effect of therapeutic lifestyle modifications (LSMs) on cardiac diastolic function and aortic stiffness in prehypertensive subjects. METHODS: This study designed as a prospective ...
Liu Yingwei - - 2013
BACKGROUND: It has been shown that (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is useful in identifying inflamed plaque in major arteries. This study evaluated the feasibility of inflamed plaque detection with routinely acquired cardiac FDG-PET viability studies in patients with severe coronary artery disease and left ventricular dysfunction. METHODS: Clinically ...
Kosuge Masami - - 2013
Although patients with Stanford type A acute aortic dissection often show ST-T abnormalities at presentation, the frequency and implication of such findings remain unclear. To clarify these points, admission electrocardiograms from 233 patients admitted ≤6 hours after symptom onset who underwent emergency surgery for type A acute aortic dissection were ...
Ising Mickey S - - 2013
Intra-aortic rotary blood pumps (IARBPs) have been used for partial cardiac support during cardiogenic shock, myocardial infarction, percutaneous coronary intervention, and potentially viable for long-term circulatory support. Intra-aortic rotary blood pump support continuously removes volume from the aortic root, which lowers left ventricular preload, external work (LVEW), and improves end-organ ...
Anderson Mark B - - 2013
The Impella microaxial pump is a catheter-based device that has been used for left ventricular support. The catheter can be inserted through a peripheral artery or directly into the ascending aorta. The pump is positioned across the aortic valve with the inflow directly in the left ventricle and the outflow ...
Webber Matthew R - - 2013
Attempted atrial transseptal puncture in a 63-year-old man undergoing an ablative procedure for atrial fibrillation was complicated by inadvertent delivery of an 8 Fr sheath across the aorta. Due to obesity-related perioperative risks, we opted for percutaneous repair rather than open-heart corrective surgery. Our case is unique for the novel ...
Smolka Grzegorz - - 2013
To evaluate the transcatheter paravalvular leak closure (TPVLC) aptitude to reduce manifestations of heart failure caused by aortic paravalvular leak (PVL). TPVLC is a valuable alternative to reoperation. While technical feasibility of the method is well established, data on long-term clinical outcome are less abundant. We launched a prospective registry ...
Takahashi Yukihiro - - 2013
Left ventricular outflow tract stenosis represents 1-2 % of all congenital anomalies. In particular, tunnel-like left ventricular stenosis which is one type of fixed left ventricular outflow stenosis requires aggressive surgery to reduce the left ventricular outflow gradient. The purpose of the modified Konno procedure is to release fixed left ventricular ...
Al Balushi Asim - - 2013
The clinical presentation of coarctation of aorta (CoA) is well known; however, it is the most common congenital heart disease in the newborn period to be missed, with significant mortality and morbidity associated with missing the diagnosis. We report a 20-day-old newborn boy who presented with congestive heart failure and ...
Zahn Ralf - - 2013
Transcatheter aortic valve implantation (TAVI) is already an accepted option to treat elderly patients with severe symptomatic aortic stenosis who are inoperable or at high surgical risk. However, short- and long-term mortality after TAVI remains an important issue, raising the need to further improve the technology of TAVI as well ...
Duerr Georg D - - 2013
AIMS: Endocannabinoids and their receptors have been associated with cardiac adaptation to injury, inflammation and fibrosis. Experimental studies suggested a role for inflammatory reaction and active remodeling in myocardial hypertrophy, but they have not been shown in human hypertrophy. We investigated the association of endocannabinoid system with myocardial hypertrophy in ...
Williams Livia - - 2013
A 65-year-old woman presented with New York Heart Association class II-III symptoms, no overt signs of heart failure, and echocardiographic findings of a quadricuspid aortic valve, Hurwitz type C, with severe aortic regurgitation, dilated left ventricle (7 cm), and moderate left ventricular dysfunction (45%). She subsequently underwent tricuspidization of the ...
Dalsgaard Morten - - 2013
BACKGROUND: Left atrial (LA) size is known to increase with chronically increased left ventricular (LV) filling pressure. We hypothesized that LA volume was predictive of aortic valve replacement (AVR) and cardiovascular events in a large cohort of patients with asymptomatic mild to moderate aortic valve stenosis. METHODS: Transthoracic echocardiography was ...
Vijayalakshmi I B - - 2013
Aorto-right ventricular tunnel (ARVT) is a very rare, congenital, abnormal extracardiac channel that connects the ascending aorta at or above the sinotubular junction to the cavity of the right ventricle. Only 16 cases have been reported thus far in the English literature. We report the first transcatheter closure of ARVT ...
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