Search Results
Results 1 - 50 of 1347
1 2 3 4 5 6 7 8 9 10 >
Pelletier-Galarneau Matthieu M From the *Division of Nuclear Medicine, and †Department of Radiology, University of Ottawa, Ottawa, Ontario, - - 2014
A 60-year-old man with history of metastatic renal cell carcinoma and atypical chest pain was referred for dipyridamole Tc-tetrofosmin perfusion scintigraphy (MPS). Two years earlier, the patient was noted to have myocardial metastases on cardiac MRI. On the MPS, perfusion defects were present at stress in multiple vascular territories; resting ...
Steiner Ivo I The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Králové, Czech Republic. Electronic address: - - 2013
A unique case of myocardial infarction due to coronary artery tumor embolism from colonic adenocarcinoma is described. A 79-year-old man with a history of rectal carcinoma with lung metastases 15 years and 9 years before, respectively, was subjected to primary percutaneous coronary intervention for myocardial infarction with aspiration of a ...
Park Kyoung-Min - - 2012
The surface electrocardiogram (ECG) is a useful tool to help identify the sites of origin of ventricular tachycardia (VT). Despite such limitations as chest wall deformity and metabolic and drug effects, the analysis of the QRS morphologic patterns and vectors can discern the site of activation of myocardium. There have ...
Ginks Matthew R MR St. Thomas' Hospital, UK. - - 2012
There is considerable heterogeneity in the myocardial substrate of patients undergoing cardiac resynchronization therapy (CRT), in particular in the etiology of heart failure and in the location of conduction block within the heart. This may account for variability in response to CRT. New approaches, including endocardial and multisite left ventricular ...
Arya Rajesh Chand - - 2012
Biventricular pacing has demonstrated improvement in cardiac functions in treating congestive cardiac failure patients. Recent trials have proven the clinical and functional benefits of cardiac resynchronization therapy in severe heart failure and intraventricular cardiac delays, mainly left bundle branch block. Biventricular pacing improves the exercise tolerance, quality of life, systolic ...
M Rgulescu Andrei D - - 2012
BACKGROUND: Fluoroscopic and electrocardiographic (ECG) criteria for the documentation of pacing lead positioning (apical and alternative sites) have been described, but data regarding their accuracy are lacking. METHODS: Fifty patients (27 men; mean age, 76 ± 9 years) with permanent right ventricular (RV) pacing leads were included. RV lead position ...
Padeletti Luigi - - 2012
BACKGROUND: -During cardiac resynchronization therapy (CRT) device implantation, the pacing lead is usually positioned in the coronary sinus (CS) to stimulate left ventricular (LV) epicardium. Transvenous LV endocardial pacing via transseptal puncture has been proposed as an alternative method. In this study, we evaluated the acute hemodynamic effects of CRT ...
Yamabe Hiroshige - - 2012
BACKGROUND:: The anatomical location of reentry circuit in verapamil-sensitive atrial tachycardia originating from the vicinity of atrioventricular node (V-AT) is not well clarified. OBJECTIVE:: The purpose of this study was to define the reentry circuit of V-AT. METHODS:: In 17 patients with V-AT, rapid atrial pacing at a rate 5 ...
Bordachar Pierre - - 2012
Background: Cardiac resynchronization therapy (CRT) is a proven treatment for heart failure but approximately 30% of patients appear to not benefit from the therapy. Left ventricular (LV) endocardial (Endo) and multisite epicardial (TriV) pacing have been proposed as alternatives to traditional LV transvenous epicardial (Epi) pacing, but no study has ...
Exner Derek V - - 2012
The rationale for cardiac resynchronization therapy (CRT), expectations in terms of patient benefit, patient selection for CRT, the selection of a CRT pacemaker (CRT-P) versus CRT plus implantable cardioverter defibrillator (CRT-D) platform, and studies evaluating device programming to enhance benefit from CRT are reviewed. The notion of an "optimal" left ...
Sasaki Osamu - - 2012
BACKGROUND: How coronary distensibility contributes to stable or unstable clinical manifestations remains obscure. We postulated that the heterogeneous plaque distensibility is associated with unstable clinical presentations in patients with acute coronary syndrome (ACS). METHODS AND RESULTS: Seventeen and 19 ACS-related and -unrelated lesions, respectively, were visualized using intravascular ultrasound imaging ...
Ploux Sylvain - - 2012
Cardiac resynchronization therapy (CRT) is an established treatment for patients with moderate-to-severe heart failure and a wide QRS complex. However, the amount of reverse remodeling and clinical improvement is highly variable and poorly predictable. The left ventricular pacing site is of critical importance for the CRT response but is often ...
Simard Trevor - - 2012
BACKGROUND: Current American Heart Association guidelines recommend against the performance of elective or primary percutaneous coronary intervention (PCI) without on-site surgical backup (i.e. a class III and IIb recommendation respectively). Despite this, numerous centers have already implemented PCI programs with no on-site surgery backup (NSOS). METHODS: To evaluate the necessity ...
Mele Donato - - 2012
BACKGROUND: In patients with ischemic heart failure undergoing cardiac resynchronization therapy (CRT) the underlying myocardial substrate at the left ventricle (LV) pacing site may affect CRT response. However, the effect of delivering the pacing stimulus remote, adjacent to or over LV transmural scar tissue (TST) identified by echocardiography is still ...
Wang Y-C - - 2012
Background:  Primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) significantly reduces mortality and morbidity, particularly when door-to-balloon (D2B) time is < 90 min. We sought to minimize preventable delays by instituting an on-site cardiology team-based approach in the emergency department (ED). Methods:  The on-site group comprised 146 consecutive ...
Kamenik Libor - - 2011
Aims. To analyze the paced QRS duration in various septal positions of the right ventricular leads and with different paced QRS vectors. To use the results to assess parameters suggesting the optimal site for right ventricular pacing. Methods and results. A total of 609 patients with leads implanted in the ...
Singh Mandeep - - 2011
Percutaneous coronary interventions are performed at centers without onsite surgery, despite current guidelines discouraging this. To assess literature comparing rates of in-hospital mortality and emergency coronary artery bypass grafting surgery at centers with and without on-site surgery. A systematic search of studies published between January 1990 and May 2010 was ...
Almendral Jesús - - 2011
ICD Electrograms and Origin of Impulses. Introduction: The implantable cardioverter-defibrillator (ICD) electrogram (EG) is a documentation of ventricular tachycardia. We prospectively analyzed EGs from ICD electrodes located at the right ventricle apex to establish (1) ability to regionalize origin of left ventricle (LV) impulses, and (2) spatial resolution to distinguish ...
Mamas Mamas A - - 2011
ObjectiveA meta-analysis of all randomised controlled studies that compare outcomes of transradial versus the transfemoral route to better define best practice in patients with ST elevation myocardial infarction (STEMI).DesignA Medline and Embase search was conducted using the search terms 'transradial,' 'radial', 'STEMI', 'myocardial' and 'infarction'.SettingRandomised controlled studies that compare outcomes ...
Bourgeois Elliot B - - 2012
The first seconds of ventricular fibrillation (VF) are well organized and can consist of just one to two rotating waves (rotors). New rotors are spawned when local propagation block causes wave fragmentation. We hypothesized that this process, which leads to fully developed VF, begins at a consistent anatomic site. We ...
Shetty Anoop K - - 2011
Pacing the left ventricle (LV) from multiple sites simultaneously may result in a better response to cardiac resynchronization therapy (CRT). We sought to assess whether multisite pacing using a quadripolar LV lead improves acute hemodynamic response (AHR) to CRT. We paced four ventricular sites simultaneously using two vectors of a ...
Katritsis Demosthenes G - - 2011
The influence of the autonomic nervous system (ANS) on triggering and perpetuation of atrial fibrillation (AF) is well established. Ganglionated plexi (GP) ablation achieves autonomic denervation by affecting both the parasympathetic and sympathetic components of the ANS. An anatomic approach for GP ablation at relevant atrial sites appears to be ...
Ginks Matthew R MR St. Thomas' Hospital, London, UK. - - 2012
Multi-site left ventricular (LV) pacing may be superior to single-site stimulation in correcting dyssynchrony and avoiding areas of myocardial scar. We sought to characterize myocardial scar using cardiac magnetic resonance imaging (CMR). We aimed to quantify the acute haemodynamic response to single-site and multi-site LV stimulation and to relate this ...
Furushima Hiroshi - - 2011
OBJECTIVE: To assess the electrophysiological characteristics of the breakout site of ventricular activation using electroanatomical voltage mapping (EVM) and its relation to the optimal ablation site in idiopathic ventricular tachyarrhythmias originating from the outflow tract of the (RVOT) septum. METHODS: Twenty-eight patients with symptomatic drug-refractory premature ventricular complexes (PVCs) and/or ...
Gao Chun-Heng - - 2011
OBJECTIVE: To investigate the feasibility of determination of right ventricular outflow tract (RVOT) high septal pacing site visualized by real-time three-dimensional echocardiography (RT3DE). METHODS: The forty subjects with RVOT pacing were analysed. RT3DE determination of RVOT high septal pacing sites was compared with chest X-ray (CXR). RESULTS: RVOT septal pacing ...
Vink Maarten A MA Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands - - 2011
To examine the feasibility of a routine transradial approach (TRA) in primary percutaneous coronary intervention (PPCI) for acute ST-segment elevation myocardial infarction (STEMI). A single-centre observational study with prospective data collection. A high-volume interventional centre in Amsterdam, The Netherlands. Procedural data were analysed for 2209 consecutive patients presenting with STEMI ...
Chan Ngai Yin - - 2011
PURPOSE: This study aimed to evaluate the utility of a novel pacing guidewire in pre-implantation testing of different left ventricular (LV) sites during cardiac resynchronization therapy (CRT) procedures. METHODS: Ten consecutive patients (8 male, mean age 65.8 ± 4.9) undergoing CRT procedures were studied. Pacing threshold and R-wave sensing measured by the ...
Alhous M Hafez A - - 2011
Aims To assess the impact of pacing from different right ventricular (RV) pacing sites on left ventricular (LV) function. Chronic apical RV pacing may induce heart failure. To reduce this RV, mid-septum and outflow tract are suggested as alternative pacing sites. We therefore assessed cardiac performance during temporary RV pacing ...
Pride Yuri B - - 2011
Prior to the widespread adoption of intracoronary stent implantation, potential complications of percutaneous coronary intervention (PCI) necessitated the presence of backup cardiac surgery. However, as stent implantation has become the predominant form of PCI, the incidence of emergent cardiac surgery has declined exponentially. Despite this, current guidelines recommend against the ...
Birati Edo Y - - 2011
Objective The electrocardiographic (ECG) characteristics and mode of onset of torsade de pointes (TdP) are well described. Less is known about the site of onset of this arrhythmia. This study was conducted to determine if arrhythmias in the long QT syndrome (LQTS) have a predominant site of origin. Design A ...
Choy Jenny S - - 2011
Background: External pumps have been previously used to minimize edema and hemorrhage caused by coronary retroperfusion. The objective of this study was to use a pump-less approach (selective autoretroperfusion, SARP) to preserve myocardial function after acute coronary artery ligation. Methods: In five experimental pigs, the LAD artery was ligated distal ...
Hamill Neil - - 2011
The objective of this study was to quantify fetal cardiovascular parameters using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL). A cross-sectional study was performed in normal pregnancies (19-42 weeks) to evaluate ventricular volume, stroke volume (SV), cardiac output (CO), and ejection fraction (EF). The CO was also ...
Shen Jeanne - - 2011
Postoperative atrial fibrillation is the most common complication after cardiac surgery. A variety of postoperative atrial fibrillation risk factors have been reported, but study results have been inconsistent or contradictory, particularly in patients with preexisting atrial fibrillation. The incidence of postoperative atrial fibrillation was evaluated in a group of 10,390 ...
Duchateau Nicolas - - 2011
In this paper, we present a new method for the automatic comparison of myocardial motion patterns and the characterization of their degree of abnormality, based on a statistical atlas of motion built from a reference healthy population. Our main contribution is the computation of atlas-based indexes that quantify the abnormality ...
Lauzier Benjamin B Departments of Nutrition, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, - - 2011
Heart rate reduction (HRR) is an important target in the management of patients with chronic stable angina. Most available drugs for HRR, such as β-blockers, have adverse effects, including on cardiac energy substrate metabolism, a well-recognized determinant of cardiac homeostasis. This study aimed at 1) testing whether HRR by ivabradine ...
Chaudhari Dhara - - 2011
Atrial fibrillation is the most common cardiac arrhythmia responsible for one third of the hospitalizations because of cardiac rhythm disturbances. Atrial fibrillation leads to stroke, heart failure, and other causes of mortality. Warfarin, a vitamin K antagonist, is the first-line agent for the prophylaxis of stroke in patients with atrial ...
Park Kyoung-Min - - 2011
A 70-year-old patient with 3-vessel coronary artery disease and a left ventricular aneurysm underwent coronary artery bypass grafting, together with a surgical anterior ventricular endocardial restoration (SAVER) procedure. Four days later, he suddenly developed recurrent sustained and nonsustained polymorphic ventricular tachycardia, preceded by monomorphic ventricular premature contractions, and did not ...
Robich Michael P - - 2011
Nonselective nonsteroidal anti-inflammatory drugs and selective cyclooxygenase-2 (COX-2) inhibitors are purported to increase adverse cardiovascular events. We hypothesized that COX-2 inhibitors would alter myocardial blood flow, microvascular reactivity, oxidative stress, and prostaglandin levels. Adult Yorkshire swine were divided into 3 groups: no drug (control, n = 7), a nonselective COX ...
Hancox Jules C - - 2010
Atrial fibrillation is the most common arrhythmia seen in clinical practice, and novel pharmacological approaches for treatment are sought. Ranolazine (Ranexa; N-(2,6-dimethylphenyl)-2-[4-(2-hydroxy-3-[2-methoxyphenoxy]propyl)piperazin-1-yl]acetamide) is used clinically for the treatment of angina pectoris. Evidence is reviewed from both pre-clinical and clinical studies, which suggests that ranolazine also exhibits antiarrhythmic activity with growing ...
Smith J Gustav - - 2010
the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality and ...
Chen Mien-Cheng - - 2011
Eur J Clin Invest 2011; 41 (3): 299-307 ABSTRACT: Background  Myolysis of atrial cardiomyocytes occurs in patients with severe mitral and tricuspid regurgitation. This morphological remodelling may involve autophagy. Methods  This study comprised 20 patients (10 with long-standing persistent atrial fibrillation and 10 with sinus rhythm) with severe mitral and ...
Kocaturk Meric - - 2010
Tei index (myocardial performance) and cardiac biomarkers were evaluated in dogs with parvoviral enteritis (PVE). Tei index was calculated as isovolumic contraction time plus isovolumic relaxation time divided by ejection time. Myocardial and skeletal muscle damages were assessed by serum levels of cardiac troponin I (cTnI), creatine (phospho) kinase, lactate ...
Aksnes Tonje A - - 2010
Atrial fibrillation is the most common clinically significant cardiac arrhythmia and is associated with markedly increased risks of cardiovascular diseases. Atrial fibrillation and hypertension often coexist and are both responsible for considerable morbidity and mortality. Aggressive treatment of hypertension, especially with a blocker of the reninangiotensin system, may postpone or ...
Xiao Junjie - - 2010
Increased atrial oxidative stress plays an important role in the pathogenesis of atrial fibrillation. A predisposition for atrial fibrillation can be produced by altering the activities of enzymes related to reactive oxygen species metabolism. Microtubule integrity is necessary for cardio-protection; microtubules are involved in many cellular processes, including enzymatic activity. ...
Danchin Nicolas - - 2010
Atrial fibrillation developing at the acute stage of myocardial infarction is associated with untoward clinical outcomes. The aim of this study was to determine correlations between early statin therapy and atrial fibrillation in acute myocardial infarction. Patients (3396) with sinus rhythm developing acute myocardial infarction were enrolled in the French ...
Sorgente Antonio - - 2010
The present review will discuss the technical aspects of a new patent invented in 1999 which allows cryoballoon ablation, an emerging technology used for the non pharmacological treatment of paroxysmal atrial fibrillation. A general evaluation of the safety and the reliability of the technique will be given together with an ...
Calò Leonardo - - 2011
Atrial fibrillation is the most common arrhythmia in clinical practice. Ion channel blocking agents are often characterized by limited long-term efficacy and several side effects. In addition, ablative invasive procedures are neither easily accessible nor always efficacious. The "upstream therapy," which includes angiotensin-converting enzyme inhibitors, aldosterone receptor antagonists, statins, glucocorticoids, ...
Naji Franjo - - 2010
Many studies have tried to propose risk factors for atrial fibrillation recurrence after a successful pharmacological or electrical cardioversion. Regarding the duration of atrial fibrillation before electrical cardioversion, only limited data exist. The aim of our study was to investigate the effect of atrial fibrillation duration on long-term sinus rhythm ...
Shah Dipak P - - 2012
Long QT eight (LQT8), otherwise known as Timothy syndrome (TS), is a genetic disorder causing hyper-activation of the L-type calcium channel Cav 1.2. This calcium load and the resultant increase in the QT interval provide the substrate for ventricular arrhythmias. We previously presented a case in a patient with TS ...
Golian Mehrdad - - 2011
We describe a case of an individual with idiopathic ventricular fibrillation whose arrhythmias were successfully controlled with phenytoin therapy.
1 2 3 4 5 6 7 8 9 10 >