Search Results
Results 401 - 450 of 1670
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Choy Jenny Susana - - 2005
Histometric data are necessary for quantifying the cellular and tissue structure which serves as a basis for the construction of mathematical and integrative models. However, fixation and histological processing of tissues such as dehydration, embedding, sectioning and staining can cause dimensional changes and tissue distortion. The present study was designed ...
Mahrholdt Heiko - - 2005
AIMS: The relationship between wall thickness, wall thickening, wall motion, and single-photon emission computed tomography (SPECT) results for detection of myocardial infarction has never been systematically evaluated in a clinical setting. In particular, the discussion whether non-ischaemic regional wall motion abnormalities and reduced wall thickness can cause SPECT to be ...
Pitman Alexander G - - 2005
BACKGROUND: Subdiaphragmatic activity and diaphragmatic motion both contribute to inferior wall artifacts in technetium 99m myocardial perfusion single photon emission computed tomography (SPECT). METHODS AND RESULTS: We used an anthropomorphic phantom with ventricular wall activity, liver/spleen inserts containing variable Tc-99m activity, and variable vertical (diaphragmatic) motion amplitude. SPECT and transmission ...
van den Bos Ewout J - - 2005
Contraction of transplanted myoblasts and their effects on function and remodeling after myocardial infarction remain controversial. We used magnetic resonance imaging (MRI) to study wall thickening and left ventricular (LV) function and geometry after myoblast transplantation. Three weeks after cryo-infarction rabbits were randomized to receive an injection of approximately 2 ...
Ingul Charlotte Bjork - - 2005
BACKGROUND: Strain rate (SR) imaging (SRI) is a tissue Doppler-based method of regional myocardial deformation imaging. The aim of this study was to see whether SRI could quantify changes in myocardial mechanical function after an acute myocardial infarction, and to follow the time course of these changes. METHODS: In all, ...
Rodriguez Filiberto - - 2005
OBJECTIVE: Helically oriented left ventricular fibers assemble into transmural sheets, which are important for wall-thickening mechanics: 15% fiber shortening results in 40% cross-fiber left ventricular wall thickening and a 60% ejection fraction through sheet extension, thickening, and shear. Normal cardiac microstructure and strains are optimized; deviations could result in apoptosis ...
Jeon Sang Beom - - 2005
Wall-eyed monocular internuclear ophthalmoplegia (WEMINO) with contraversive ocular tilt reaction has not been previously reported. A 71-year-old woman suddenly developed blurred vision. Examination revealed left internuclear ophthalmoplegia, left exotropia, right hypotropia, and rightward head tilt. Magnetic resonance imaging showed a tiny infarction at the area of the left medial longitudinal ...
Lindner Oliver - - 2005
In patients with dilated cardiomyopathy (DCM), left bundle branch block (LBBB) is a common finding. The characteristic feature is an asynchronous septal wall motion and most frequently a delay of the lateral and/or posterior wall segments. With the onset of cardiac resynchronization therapy, there is a focus on the specific ...
Lapeyre André C AC - - 2005
BACKGROUND: Gated single photon emission CT (SPECT) sestamibi imaging allows the simultaneous assessment of myocardial perfusion and left ventricular function. OBJECTIVE: The purpose of this study was to evaluate a technique for quantitative regional wall motion assessment using gated SPECT (99m)Tc-sestamibi imaging. PATIENTS AND INTERVENTIONS: Fourteen subjects without cardiac pathology ...
Turiel Maurizio - - 2005
Connective tissue diseases (CTD) lead to a high prevalence of common cardiac manifestations (pericarditis and myocarditis) and of ischemic coronary events with a considerable increase in cardiac mortality related to premature atherosclerosis. Although there are several techniques able to detect cardiac involvement in CTD patients, the most useful and non-invasive ...
Khush Kiran - - 2005
Cardiac injury, including left ventricular dysfunction, frequently occurs in patients with subarachnoid hemorrhage. Patterns of left ventricular dysfunction often do not follow coronary artery distributions, and may correlate with myocardial sympathetic innervation. Left ventricular dysfunction of the anterior and anteroseptal walls that spares the apex is unusual for patients with ...
O'Donnell Thomas - - 2005
Cine-DEMR is a new cardiac imaging technique which combines aspects of Cine and Delayed Enhancement MR. Like Cine, it displays the heart beating over time allowing for the detection of motion abnormalities. Like DEMR, non-viable (dead) tissues appear with increased signal intensity (it has been shown that the extent of ...
Indik Julia H - - 2005
BACKGROUND/AIM: Patients with ventricular ectopy from the right ventricular (RV) outflow tract (RVOT) are often referred for RV angiography to exclude disorders such as arrhythmogenic RV cardiomyopathy/dysplasia (ARVC/D). This is usually based on a qualitative assessment of the wall motion. We present a method to quantify the wall motion and ...
Kolipaka Arunark - - 2005
PURPOSE: To define the relationship between left ventricular (LV) regional contractile function and the extent of myocardial scar in patients with chronic ischemic heart disease and multi-vessel coronary artery disease. METHODS: Twenty-three patients with chronic ischemic heart disease and 5 healthy volunteers underwent magnetic resonance imaging (MRI). In patients, the ...
Liu Yani - - 2005
To assess the left ventricular longitudinal regional myocardial systolic function by strain imaging (SI) echocardiography and to study the relationship between regional myocardial systolic function and left ventricular structure in patients with hypertrophic cardiomyopathy (HCM). SI echocardiography were performed in 18 patients with HCM and 17 healthy subjects. For each ...
De Souza Andrea Pereira - - 2005
Caveolin-1 and caveolin-3 are expressed in the mammalian heart. Mice deficient in caveolin 1 or 3 exhibit cardiac abnormalities including left ventricular hypertrophy and reduced fractional shortening. Cardiac imaging technologies such as transthoracic echocardiography and cardiac-gated magnetic resonance imaging (MRI) are effective tools for the study of left ventricular morphology ...
Petitjean Caroline - - 2005
Tagged MRI provides a noninvasive way to assess the regional function of the heart. Clinical use of myocardial strain measurements from tagged MRI requires identifying new normative values. As for cardiac motion estimation, a variety of methods for quantifying myocardial deformations have been proposed in the image analysis and medical ...
Konofagou E E Associate Member, IEEE, departments of biomedical engineering and radiology of Columbia University, New York, NY 10032, USA (212-342-0863; fax: 212-342-5773; e-mail: - - 2005
The main purpose of this paper is to develop a theoretical tool in order to fundamentally characterize the performance of Myocardial Elastography and identify the optimal parameters to be used for the more reliable detection of ischemia or infarction. A complete representation of the left-ventricular function throughout an entire cardiac ...
Manivannan J J Biomedical Engineering Division, IIT MADRAS, Chennai, - - 2005
This paper presents a new technique for identification of regional dysfunctions in the left ventricle from 2-D echocardiography. It uses a novel left ventricular border tracking algorithm based on Fuzzy inference system. In this paper we show how the regional dysfunction present in the left ventricle can be identified by ...
Ordas Sebastian S Computational Imaging Laboratory, Department of Technology, University Pompeu Fabra, E08003 Barcelona, - - 2005
This work presents a fully automatic method for regional myocardial contraction and motion assessment in cardiac cine MRI studies. The prerequisite of segmenting the left ventricle at all temporal phases of the study, is accomplished using a statistical model-based algorithm (3D- ASM). Subsequent functional analysis includes the assessment of LV ...
Dang Alan B C - - 2005
Infarcted segments of myocardium demonstrate functional impairment ranging in severity from hypokinesis to dyskinesis. We sought to better define the contributions of passive material properties (stiffness) and active properties (contracting myocytes) to infarct thickening. Using a finite-element (FE) model, we tested the hypothesis that infarcted myocardium must contain contracting myocytes ...
Heijman E - - 2004
In this paper we introduce an improved harmonic phase (HARP) analysis for complementary spatial modulation of magnetization (CSPAMM) tagging of the mouse left ventricular wall, which enables the determination of regional displacement fields with the same resolution as the corresponding CINE anatomical images. CINE MRI was used to measure global ...
Otani Kentaro - - 2004
BACKGROUND: Although stress myocardial contrast echocardiography (MCE) can be used to detect coronary stenosis, its efficacy relative to other methods, such as detection of wall-motion abnormalities, remains unknown. Thus, the goal of this study was to compare the sensitivity of MCE versus wall-motion abnormality detection in the assessment of coronary ...
Mohan H K - - 2004
Left ventricular ejection fraction (LVEF) and wall thickening are fundamental aspects of cardiac function. Recently, gated single photon emission computerised tomography (GSPECT) and anatomical M-mode echocardiography are new techniques, which have been introduced for the evaluation of left ventricular wall thickening and ejection fraction. These, however, have not been evaluated ...
Lim Hong Euy - - 2004
Recent studies have demonstrated that the size and shape of the hyperenhanced areas on contrast-enhanced magnetic resonance imaging (ceMRI) were nearly identical to areas of irreversible injury, as defined by histochemical staining. We compared the transmural extent of infarct (TEI), as defined by ceMRI, to the initial ECG findings for ...
Beer Meinrad - - 2004
PURPOSE: To determine whether the recently applied technique of acquisition-weighted 31P-MR spectroscopy (AW-MRS) allows for the detection of depressed energy metabolism in patients with inferior wall myocardial infarctions. MATERIALS AND METHODS: Eight patients with subacute myocardial infarction and wall motion abnormalities restricted to the inferior wall were examined with a ...
Thomas Boban - - 2004
OBJECTIVES: A protocol to evaluate myocardial viability in ischemic left ventricular dysfunction using magnetic resonance imaging and a gadolinium-based contrast agent. METHODS: Twenty-two patients were prospectively offered a cardiac MR exam between November 2003 and June 2004. Twelve had a history of anterior wall MI, eight had a history of ...
Aziz Tariq A - - 2004
A 39-year-old man with idiopathic dilated cardiomyopathy and New York Heart Association Class III heart failure symptoms underwent orthotopic cardiac transplantation. Post-operatively, he developed an anteroseptal infarct pattern on the electrocardiogram (ECG), without regional wall motion abnormalities according to echocardiography. This pseudo-infarct pattern on ECG resolved within 6 months without ...
Gilson Wesley D - - 2005
Cardiac MRI is an accurate, noninvasive modality for assessing the structure and function of the murine heart. In addition to conventional imaging, MRI tissue tracking methods can quantify numerous aspects of myocardial mechanics, including intramyocardial displacement, strain, twist, and torsion. In the present study, we developed and applied a novel ...
Takahashi Takefumi - - 2004
This study examined whether coronary flow reserve (CFR) measured immediately after primary coronary stenting could predict wall motion recovery in patients who have acute myocardial infarction. CFR significantly correlated with the change of wall motion score (r = 0.68, p <0.0001), and the optimal cut-off value of CFR for predicting ...
García Ricardo A - - 2005
Activation of matrix metalloproteinases (MMPs) in the heart is known to facilitate cardiac remodeling and progression to failure. We hypothesized that regional dyskinetic wall motion of the left ventricle would stimulate activation of MMPs. Abnormal wall motion at a target site on the anterior lateral wall of the left ventricle ...
Wang Jianwen - - 2004
In this prospective, observational study, we evaluated whether transesophageal echocardiography allows for monitoring left ventricular segmental wall motion during cardiac displacement for off-pump coronary artery bypass (OPCAB) surgery. On the basis of a pilot study that showed frequent loss of transgastric views during OPCAB surgery, we analyzed only midesophageal views. ...
Matsuoka Koji - - 2004
A 57-year-old woman had transient right hemiplegia 2 days after physical stress. An electrocardiogram exhibited T-wave inversion with QT prolongation. An echocardiogram revealed akinesia of the entire left ventricle except for the basal region. Cranial computed tomography and transthoracic echocardiography revealed an apical thrombus that disappeared 1 month later. Coronary ...
Chiou Kuan-Rau - - 2004
BACKGROUND: Real-time myocardial contrast echocardiography (MCE) makes possible the simultaneous visualization of changes in perfusion imaging and wall motion. OBJECTIVES: To assess the accuracy of real-time MCE for detecting the presence and extent of coronary artery disease (CAD), and to evaluate the correlation between wall motion and myocardial perfusion by ...
Neuman Yoram - - 2004
One hundred fifty patients with their first acute myocardial infarctions (AMIs) were studied. AMIs were confirmed by troponin levels, ST-segment elevation, or angiographic coronary occlusion. In 36% of patients (16 of 45) with left ventricular (LV) hypertrophy, the wall motion score index was normal, whereas in patients with no LV ...
Yao Siu-Sun - - 2004
The prognostic value of stress echocardiography to predict future cardiac events using the extent and severity of wall motion abnormalities is not well defined. The objective of this study was to develop and validate a prognostic model for interpretation of stress echocardiographic studies by using the extent and severity of ...
Caldas Márcia A - - 2004
OBJECTIVE: We sought to study the value of microvascular perfusion assessed by myocardial contrast echocardiography in predicting left ventricular remodeling after anterior wall acute myocardial infarction. METHODS: In 31 patients myocardial contrast echocardiography was performed up to 48 hours after acute myocardial infarction with determination of end-diastolic and end-systolic volumes, ...
Wheat Janelle M - - 2004
OBJECTIVE: Advances in 99mTc-based radiopharmaceuticals and multiple-detector gantries have the potential to increase the significance of patient motion on the diagnostic integrity of myocardial perfusion SPECT acquisitions. METHODS: An experimental study was used to evaluate the effect of various patient motions on the diagnostic integrity of myocardial perfusion SPECT data ...
Eder V?ronique - - 2004
BACKGROUND: We have elaborated a new software called ACS designed for left ventricle 3-dimensional reconstruction and quantitative analysis of regional wall motion using gated blood-pool tomography (GBPS). This paper presents the principle and the validation of this software. METHODS AND RESULTS: Blood pool tomography was reconstructed by filtered back-projection. Voxels ...
Kurtoglu Z - - 2004
The heart of an anencephalic baby can be used as a donor after death. There exists insufficient information in literature, however, for the possible morphological differences in anencephalic hearts. This study compares ventricular myocardial thicknesses of anencephalic fetuses with normal fetuses in the same gestational age group. The comparison was ...
Miyazaki Shinsuke - - 2004
Myocardial stunning with hyperthyroidism is rare. A 79-year old woman with hyperthyroidism was admitted to our hospital complaining of palpitations due to paroxysmal atrial fibrillation. An echocardiogram showed akinesis of the apical wall which was not observed 2 weeks before admission. Cardiac catheterization performed in the acute phase showed normal ...
Schuijf Joanne D - - 2004
Contrast-enhanced magnetic resonance (ce-MR) imaging allows precise delineation of infarct transmurality. An issue of debate is whether data analysis should be performed visually or quantitatively. Accordingly, a head-to-head comparison was performed between visual and quantitative analyses of infarct transmurality on ce-MR imaging. In addition, infarct transmurality was related to the ...
Oyer Calvin E - - 2004
To evaluate valvular stenosis, cardiac dilation, and/or cardiac hypertrophy, measurements of valve circumference and ventricular wall thickness are of importance. To establish reference values in fetuses and neonates, we reviewed pathology reports at Women and Infants Hospital from 1978 through 2002 and found measurements in 776 cases that were suitable ...
Ashikaga Hiroshi - - 2004
To test the hypothesis that the abnormal ventricular geometry in failing hearts may be accounted for by regionally selective remodeling of myocardial laminae or sheets, we investigated remodeling of the transmural architecture in chronic volume overload induced by an aortocaval shunt. We determined three-dimensional finite deformation at apical and basal ...
Devaux B - - 2004
BACKGROUND: Adrenalectomy for pheochromocytoma is a life-threatening procedure. Few echocardiographic assessments have been reported in patients undergoing adrenalectomy for pheochromocytoma. METHODS: Sixty-three consecutive patients undergoing adrenalectomy for pheochromocytoma underwent routine preoperative M-mode and two-dimensional echocardiography, and Doppler examination. Abnormal echocardiographic findings were defined as left ventricular dilatation or dysfunction (left ...
Maniar Hersh S - - 2004
OBJECTIVE: Magnetic resonance imaging with radiofrequency tissue tagging permits quantitative assessment of regional systolic myocardial strain. We sought to investigate the utility of this imaging modality to quantitatively determine preoperative impairment and postoperative improvement in ventricular function in patients with ischemic heart disease. METHODS: Magnetic resonance imaging with radiofrequency tissue ...
Almeda Francis Q - - 2004
BACKGROUND: Hibernating myocardium is defined as a state of persistently impaired myocardial function at rest due to reduced coronary blood flow that can partially or completely be restored to normal if the myocardial oxygen supply/demand relationship is favorably altered. Percutaneous laser revascularization (PMR) is an emerging catheter-based technique that involves ...
Giubbini Raffaele - - 2004
PURPOSE: The aim of this study was the evaluation of septal wall motion, perfusion and wall thickening after CABG in two groups of consecutive patients, one with grafted left anterior coronary artery and no history of myocardial infarction, and the other with previous anteroseptal myocardial infarction and impaired septal motion ...
Fauchier Laurent - - 2004
There is considerable variability in segmental wall motion abnormalities and in the prognosis of idiopathic dilated cardiomyopathy (IDC). Radionuclide ventriculography with Fourier analysis was performed in 107 patients with angiographically proved IDC. Amplitude analysis located the wall motion abnormalities. Using phase analysis in the left and right ventricles, the interventricular ...
Axel Leon - - 2004
BACKGROUND: The papillary muscles (PMs) play an important role in normal cardiac function, helping to prevent leakage through the AV valves during systole. The nature of their attachment to the heart wall can affect the understanding of their function. This attachment is conventionally portrayed as a direct connection of their ...
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