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Scantlebury Dawn C DC Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo - - 2014
Takotsubo cardiomyopathy, also known as left ventricular apical ballooning syndrome and stress-induced cardiomyopathy, is typically characterized by transient systolic dysfunction of the apical and mid-segments of the left ventricle, in the absence of obstructive coronary artery lesions. Patients may present with symptoms and signs of acute coronary syndrome, and the ...
Ferlini Marco M UO Cardiologia, Laboratorio di Emodinamica, Fondazione IRCCS, Policlinico San Matteo, Pavia, - - 2014
A 51-year-old man was hospitalized for recurrence of acute coronary syndrome after few months. Coronary angiography during first hospitalization showed no significant coronary stenosis, while the second time, right coronary artery presented an expansion at the proximal segment. Optical coherence tomography documented a long fibroatheroma with an ulceration and residual ...
Kamenický Peter P Univ Paris-Sud, Faculté de Médecine Paris-Sud (PK, SS, SB, JY, PC), F-94276 Le Kremlin Bicêtre, France; Sorbonne Universités, UPMC Univ Paris 06, Faculté de Médecine (AR, NK), F75006 Paris, France; Université Paris Descartes, Faculté de Médecine (EM), F75006 Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction (PK, SS, JY, PC) and Service de Pharmacogénétique, Biochimie Moléculaire et Hormonologie (SB), F-94275 Le Kremlin Bicêtre, Hôpital Pitié-Salpêtrière, Département d'Imagerie Cardiovasculaire (AR) and Service d'Endocrinologie (CJ), F75013 Paris and Hôpital Européen George Pompidou, Service de Radiologie Cardiovasculaire (CR, LM, AA, ZR, EM), F75015 Paris, and Hôpital Cochin, Service d'Endocrinologie (LG), F75006 Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U693 (PK, JY, SB, PC), F-94276 Le Kremlin Bicêtre and UMR 7371, UMR S 1146, Laboratoire d'Imagerie Biomédicale, ICAN Imaging Core Lab (AR, NK) F-75013 Paris, - - 2014
Background: Patients with Cushing's syndrome have LV hypertrophy and dysfunction on echocardiography, but echo-based measurements may have limited accuracy in obese patients. No data are available on RV and LA size and function in these patients. Objectives: To evaluate left ventricular (LV), right ventricular (RV) and left atrial (LA) structure ...
Minha Sa'ar S MedStar Washington Hospital Center, 110 Irving St, NW, Suite 4B, Washington, DC 20010 USA. - - 2014
An important subset of patients presenting with acute coronary syndrome (ACS) are found to have either normal coronaries (NCs) or non-obstructive coronary artery disease (NOCAD; lumen diameter narrowing <50%). To explore the characteristics and management strategies in this population in a real-world setting. The Acute Coronary Syndrome Israeli Survey (ACSIS) ...
Basra Sukhdeep S SS Division of Cardiology, Baylor College of Medicine, Houston, TX 77030, - - 2014
Non-ST elevation acute coronary syndromes (NSTE-ACS) encompass the clinical entities of unstable angina and non-ST elevation myocardial infarction. Several advances have occurred over the past decade, including the emergence of new antiplatelet and antithrombotic therapies and novel treatment strategies, leading to marked improvements in mortality. However, there has also been ...
Kurtul Alparslan A Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey - - 2014
N-terminal pro-brain natriuretic peptide (NT-proBNP) levels are associated with short- and long-term mortality in acute coronary syndrome (ACS). We investigated whether baseline NT-proBNP levels are associated with burden of coronary atherosclerosis assessed by SYNTAX score (SXScore). We enrolled 509 patients with ACS who underwent coronary angiography. The patients were divided ...
Arbelo Elena E Arrhythmia Section, Cardiology Department, Thorax Institute, Hospital Clinic, C/Villarroel 170, 6° Planta - Escalera 3, 08036, Barcelona, Spain, - - 2014
The Brugada syndrome (BS) is a hereditary disease characterized by typical electrocardiographic alterations (elevation of the ST segment in right precordial leads) that affects young individuals without structural heart disease, predisposing them to ventricular arrhythmias and sudden death (SD). Several genetic mutations of different subunits of the sodium, calcium and ...
Khan Razi R Department of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, - - 2014
Transradial access (TRA) is becoming increasingly used worldwide for percutaneous coronary intervention (PCI) after acute coronary syndromes (ACS). TRA compared with transfemoral access has been noted to improve clinical outcomes in clinical trials and large registry cohort studies. However, much of the benefits of TRA PCI are noted in patients ...
Besic Kristina Maric KM Department of Cardiovascular Medicine, University Hospital Centre Zagreb, Zagreb, Croatia. Electronic address: - - 2014
We compared efficacy of bare-metal stent (BMS) and drug-eluting balloon (DEB) combination vs BMS alone, in patients with non-ST elevation acute coronary syndrome treated with percutaneous coronary intervention (PCI). Patients with non-ST elevation myocardial infarction (NSTEMI) or unstable angina (UA) were randomized to BMS only or BMS+DEB group. Angiographic follow-up ...
Hammel James M JM Division of Cardiovascular Surgery, University of Nebraska Medical Center College of Medicine, and Children's Hospital and Medical Center, Omaha, NE, - - 2014
We describe a relatively long left ventricular recruitment pathway consisting of early and serial aortic valvuloplasties and multiple endocardial fibroelastosis resections resulting in successful biventricular conversion of hypoplastic left heart syndrome.
Cortez-Dias Nuno N Unidade de Arritmologia Invasiva, Serviço de Cardiologia, Hospital de Santa Maria, Centro Hospitalar de Lisboa Norte, Lisboa, Portugal; Clínica Universitária de Cardiologia, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal. Electronic address: - - 2014
We present the case of a 60-year-old woman with Brugada syndrome, permanent type 1 electrocardiographic pattern, who had previously received an implantable cardioverter-defibrillator. She suffered frequent syncopal episodes and multiple appropriate shocks (around five per month) due to polymorphic ventricular tachycardia/ventricular fibrillation, refractory to quinidine therapy. Combined epicardial and endocardial ...
Bagai Akshay A From the Terrence Donnelly Heart Centre, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada (A.B.); Mount Sinai Medical Center and The Cardiovascular Research Foundation, New York, NY (G.D.D.); Columbia University Medical Center and The Cardiovascular Research Foundation, New York, NY (G.W.S.); and Duke Clinical Research Institute, Durham, NC (C.B.G.). - - 2014
The appropriate timing of angiography to facilitate revascularization is essential to optimize outcomes in patents with ST-segment-elevation myocardial infarction and non-ST-segment-elevation acute coronary syndromes. Timely reperfusion of the infarct-related coronary artery in ST-segment-elevation myocardial infarction both with fibrinolysis or percutaneous coronary intervention minimizes myocardial damage, reduces infarct size, and decreases ...
Smukowska-Gorynia Anna A 1st Department of Cardiology, University of Medical Sciences, Poznan, - - 2014
The antiphosholipid syndrome (APS) is an autoimmune disorder, characterized by the presence of vascular thrombosis and/or pregnancy morbidity in a patient with positive laboratory tests for antiphospholipid antibodies. The patients with APS are in the high risk of rethrombosis. We report the case of 43-year-old female presenting with recurrent acute ...
Boynosky Nicole A NA Dermatology Department, Veterinary Specialty Hospital, 10435 Sorrento Valley Road, San Diego, California 92121, - - 2014
A 2-year-old neutered male golden retriever dog presented for lameness secondary to ulcerations of multiple digital paw pads was diagnosed with vasculitis and hypercholesterolemia. Despite treatment, ischemic necrosis progressed to include all distal extremities and the dog eventually expired due to myocardial infarction secondary to severe atherosclerosis. The rapid demise ...
Ahmed Emad E Department of Adult Cardiology & Cardiovascular Surgery, Heart Hospital, Hamad Medical Corporation (HMC), Doha, - - 2014
Aims: To evaluate the presentation and outcome of South Asian (SAP) to Middle Eastern Arabs (MEAP) patients presenting with acute coronary syndrome. Methods: Data were collected retrospectively in Qatar between 1991 and 2010, and were analyzed according to patient ethnicity. Results: Of 14,593 acute coronary syndrome patients, 49% were MEAP ...
Al-Aqeedi Rafid Fayadh RF Department of Cardiology, Erbil Teaching Hospital, Erbil, Kurdistan, - - 2014
Generally, patients with prior coronary artery bypass graft (CABG) are often under-represented in acute coronary syndrome (ACS) clinical trials. Nevertheless, there is growing global attention concerning their short- and long-term prognosis. Some reports suggest prior CABG as an independent risk factor for increased mortality, while others report an equal or ...
Bangalore Sripal S From the Department of Medicine, Division of Cardiology, New York University School of Medicine (S.B.); Department of Biostatistics and Bioinformatics, Duke Clinical Research Institute, Durham, NC (M.J.P.); Department of Cardiology, The Methodist DeBakey Heart and Vascular Center, Houston, TX (N.S.K.); and Department of Cardiology, Saint-Luke's Mid America Heart Institute, University of Missouri-Kansas City School of Medicine - - 2014
The use of bivalirudin versus unfractionated heparin monotherapy in patients without ST-segment-elevation myocardial infarction is not well defined. The study population consisted of patients enrolled in the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) registry with either non-ST-segment-elevation acute coronary syndromes or stable ischemic heart disease, who underwent percutaneous ...
Nomura Tetsuya - - 2014
Although several etiopathogenetic mechanisms have been proposed, the causes of left ventricular apical ballooning syndrome are still controversial. A 51-year-old Japanese woman consulted the emergency room complaining of the sudden onset of anterior chest pain while shopping. We initially suspected her disease as left ventricular apical ballooning syndrome based on ...
Agarwal Ajay A Department of Medicine, Dayton Veteran Affairs Medical Center, Dayton, OH 45428, USA ; Wright State University, Dayton, OH 45409, - - 2014
A 77-year-old male patient presented with rhabdomyolysis. He developed progressive respiratory failure and acute respiratory distress syndrome during his hospital stay requiring mechanical ventilation. An electrocardiogram during mechanical ventilation showed findings suggestive of ST elevation myocardial infarction. Closer review showed dome and spike findings that have been likened to a ...
Bassand Jean-Pierre JP Department of Cardiology, EA3920, University Hospital Jean Minjoz, Besançon, - - 2014
Despite widespread adoption of acetylsalicylic acid and P2Y12 receptor inhibitor therapy as the standard of care for secondary event prevention in patients with acute coronary syndrome (ACS), the rate of cardiovascular death or myocardial infarction following discharge is approximately 24-31% over five years, indicating an important unmet need to reduce ...
Parks Natalie E NE Division of Neurology, Department of Medicine, Dalhousie University, - - 2014
Migrainous infarction accounts for 12.8% of ischemic strokes of unusual etiology. A 59-year-old woman with longstanding migraine with aura experienced what appeared to be migrainous infarction characterized by dysmetropsia and transient Cotard's syndrome. Imaging demonstrated right temporal-parietal-occipital changes with apparent cortical laminar necrosis. The spectrum of the pathophysiology of migrainous ...
Refaat Marwan M Marwan Refaat, Mostafa Hotait, Brion Winston, Department of Cardiology, American University Medical Center, Beirut 110 72020, - - 2014
Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders caused by collagen synthesis defects. Several hemostatic abnormalities have been described in EDS patients that increase the bleeding tendencies of these patients. This case report illustrates a patient with an unusual presentation of a patient with type IV EDS, ...
Davis Mary E ME *Division of Cardiovascular Medicine (Davis, Haglund, and Keebler), †Department of Cardiac Surgery (Tricarico and Maltais), Vanderbilt University Medical Center, Nashville, TN - - 2014
Percutaneous continuous-flow (CF) micro axial blood pumps, like the Impella 5.0, are commonly used for short-term (ST) mechanical circulatory support in patients with acute decompensated heart failure (1). The Impella device often serves as a bridge to implantation of a long-term (LT) CF left ventricular assist device (CF-LVAD), such as ...
Steigen Sonja E - - 2014
Abstract Objectives: Patients previously treated with coronary stents may suffer an acute coronary syndrome (ACS) without any evidence of thrombus formation on coronary angiography (CAG). This may be due to partial, non-occlusive stent thrombosis with microembolization. In this paper we illustrate possible mechanisms both with Optical coherence tomography (OCT) and ...
Tülümen Erol E University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany; DZHK (German Centre for Cardiovascular Research) partner site Mannheim, Germany; Dr. Tülümen and Dr. Giustetto equally contributed to this manuscript.. Electronic address: - - 2014
Patients with a short QT syndrome (SQTS) have an increased risk for atrial, ventricular tachyarrhythmias and/or sudden cardiac death. PQ segment depression (PQD) is related to atrial fibrillation and carries a poor prognosis in the setting of acute inferior myocardial infarction and is a well defined ECG marker of acute ...
Taglieri Nevio N From the *Istituto di Cardiologia, Dipartimento di Medicina Specialistica Diagnostica e Sperimentale Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna, Italy, †Medicina Nucleare, Dipartimento di Medicina Specialistica Diagnostica e Sperimentale Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna, Italy, and ‡Radiologia, Dipartimentodi Medicina Specialistica Diagnostica e Sperimentale Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Bologna, - - 2014
Patients with non-ST-segment elevation myocardial infarction (NSTEMI) represent a heterogeneous group in terms of jeopardized myocardium, pathogenetic mechanisms, and risk of recurrent events. In particular, estimation of myocardium at risk may be challenging before angiography. Yet the mechanisms leading to coronary instability underlying acute coronary syndromes (ACS) have not been ...
Moscarelli Marco M Department of Surgery and Cancer, Imperial College London, London, - - 2014
Although the European Society of Cardiology and AHA/ACC guidelines provide some suggestions regarding coronary artery bypass grafting (CABG) in the acute coronary syndrome (ACS), the exact indications for surgery in this diverse spectrum of disease requires further clarification. ACS may present with different scenarios, from NSTEMI to cardiogenic shock. Primary ...
Biglino Giovanni G Centre for Cardiovascular Imaging, UCL Institute of Cardiovascular Science, University College London, and Cardiorespiratory Division, Great Ormond Street Hospital for Children, National Health Service Foundation Trust, London, United Kingdom. Electronic address: - - 2014
To assess the coupling efficiency in hypoplastic left heart syndrome, considering the effect of surgical arch reconstruction and the shunt type received during the Norwood procedure. Ventriculoarterial coupling was assessed before Fontan completion in 32 patients with hypoplastic left heart syndrome (19 modified Blalock-Taussig and 13 Sano shunts at stage ...
Kunadian Vijay V Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University and Cardiothoracic Centre, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, United - - 2014
Early administration of glycoprotein IIbIIIa inhibitors results in improved angiographic parameters, including thrombolysis in myocardial infarction (TIMI) flow grade, corrected TIMI frame count, and TIMI myocardial perfusion grade (TMPG) among patients with ST-segment elevation myocardial infarction. Whether the same is true in the setting of non-ST-segment elevation acute coronary syndrome ...
Noonan P M E - - 2014
Mortality outcomes associated with surgical palliation for hypoplastic left heart syndrome have continued to improve with time. Despite these advances, inter-stage mortality continues to be difficult to predict and prevent. This case report details a three year old boy with hypoplastic left heart syndrome palliated with a Glenn shunt who ...
Jang Ji Hun JH Division of Cardiology, Department of Internal Medicine, Inha University School of Medicine, Incheon, - - 2014
Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome and sudden cardiac death. The incidence, causes, pathogenesis, and treatment have not been defined clearly, but spontaneous coronary artery dissection should be considered in young patients without major cardiovascular risk factors or in patients in the peripartum period ...
Heseltine Thomas David TD Department of Medicine, Leighton Hospital, Crewe, - - 2014
We describe the case of a 65-year-old patient who was admitted to our tertiary centre with cardiac sounding chest pain and inferior ST elevation. Coronary angiography revealed mild plaque disease in the left anterior descending artery. The right coronary artery was smooth with no plaques with the exception of an ...
Hung Chi-Sheng CS Department of Internal Medicine (Cardiology Division), National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, - - 2014
Coronary artery disease (CAD) is associated with abdominal obesity and metabolic syndrome. Adipocytes secrete adipokines, including the newly discovered adipocyte fatty acid binding protein (A-FABP) and chemerin. Adipokines contribute to the pathogenesis of CAD. In patients with CAD, the presence of significant ischemia predicts adverse outcomes. It is unknown whether ...
Misaka Tomofumi T 0000-0003-4795-9334 Department of Cardiology and Hematology, Fukushima Medical University, 1 Hikarigaoka, Fukushima 960-1295, - - 2014
Background. Soluble lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) level is a novel biomarker for diagnosis of acute coronary syndrome (ACS); however, this level in the coronary circulation has yet to be examined. Methods. Twenty-seven consecutive patients with ACS and 40 patients with effort angina pectoris (EAP) undergoing percutaneous coronary intervention ...
Saba Sami S Department of Neurology, NYU, New York, New York, - - 2014
A 63-year-old man with an isolated infarction of the corpus callosum developed expressive aphasia in addition to the deficits traditionally associated with a disconnection syndrome.
Anantha Narayanan Mahesh M 0000-0001-5894-7406 Department of Internal Medicine, Creighton University School of Medicine 601 N 30th Street No. 5800, Omaha, NE 68131, - - 2014
We present a case of reversible stress cardiomyopathy in a surgical patient, described here as a forme fruste due to its atypical features. It is important to recognize such unusual presentation of stress cardiomyopathy that mimics acute coronary syndrome. Stress cardiomyopathy commonly presents as acute coronary syndrome and is characterized ...
Desmet Walter W University Hospitals Leuven, Leuven, - - 2013
Even after coronary angiography, transient left ventricular ballooning syndrome (TLVBS) can be misdiagnosed as ST-elevation myocardial infarction (STEMI) caused by transient thrombotic occlusion of the left anterior descending artery, as the appearance of the left ventricular angiograms is often very similar. As prognosis and antithrombotic treatment of these two conditions ...
Ice Daniel S DS Division of Cardiovascular Diseases, Lankenau Medical Center and Lankenau Institute of Medical Research, Wynnewood, Jefferson Medical College, Philadelphia, Pennsylvania. Electronic address: - - 2014
The best regimen for the long-term management of patients with atrial fibrillation who present with an acute coronary syndrome or require placement of a coronary stent remains unclear. Clinicians need to understand the risk of stroke, stent thrombosis, and major bleeding associated with treating these patients. Numerous studies and risk ...
Fitchett David - - 2013
Atrial fibrillation in patients with acute coronary syndrome (ACS) is associated with a high thromboembolic event rate. Combined oral anticoagulant (OAC) and antiplatelet therapy (APT) are often used to reduce thromboembolic risk, recurrent coronary ischemic events, and stent thrombosis, despite the high bleeding risk. This review is timely with the ...
Mlakar Polona - - 2013
Abstract Background: High-sensitivity C-reactive protein (hsCRP) is an important biomarker of risk for coronary heart disease morbidity and mortality. We investigated the influence of short-term cardiac rehabilitation (CR) after acute myocardial infarction (AMI) on values of hsCRP and classical risk factors, including metabolic syndrome. Methods: hsCRP and classical risk factors ...
Michaud Katarzyna K University Center of Legal Medicine, Lausanne-Geneva, Rue du Bugnon 21, 1011 Lausanne, Switzerland. Electronic address: - - 2014
Cocaine is a well known trigger of acute coronary syndromes. Over the last 10 years levamisole, a veterinary anthelminthic drug has been increasingly used as an adulterant of cocaine. Levamisole was used to treat pediatric nephritic syndrome and rheumatoid arthritis before being withdrawn from the market due to its significant ...
Sacher Frederic F Bordeaux University Hospital, F-33000 Bordeaux, France; Univ. Bordeaux, L'Institut de RYthmologie et de modelisation Cardiaque, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, F-33000, Bordeaux, France. Electronic address: - - 2013
We present the case of a 14-year-old female with early repolarization syndrome who presented with recurrent ventricular fibrillation and ICD shocks which were refractory to multiple drugs and catheter ablation. Treatment with quinidine, an Ito blocker, resulted in a normalization of J waves and suppression of VF. Interestingly, J wave ...
Chudek Jerzy J Department of Pathophysiology, Medical University of Silesia, Katowice, - - 2014
Double antiplatelet therapy with clopidogrel and acetylsalicylic acid is a standard procedure after acute coronary syndrome. This treatment carries a higher risk of complications. The main goal of this research was to assess the patients' quality of life after undergoing antiplatelet therapy with clopidogrel after acute coronary syndrome (ACS). In ...
Aykan Ahmet Cağrı - - 2013
The aim of the present study was to assess the association between metabolic syndrome (MS) and coronary artery disease (CAD) complexity assessed by SYNTAX score (SS) and severity in non-diabetic patients with stable CAD whom underwent coronary angiography and to evaluate whether the MS defined by different definitions including International ...
Davidson Laura L Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: - - 2013
Acute coronary syndrome due to acute plaque rupture has been well described and is associated with established risk factors, including hypertension, diabetes mellitus, hyperlipidemia, and smoking. The prevalence of these risk factors in very young patients (aged ≤35 years) is not well known, and they may have other nontraditional risk ...
Chang Kuai-Le KL Department of Cardiology, 3rd Hospital of the Chinese People's Liberation Army, 45 Dongfeng Road, Baoji, Shaanxi Province, - - 2013
Kounis syndrome has been defined as an acute coronary syndrome that manifests as unstable vasospastic or nonvasospastic angina, and even as acute myocardial infarction. It is triggered by the release of inflammatory mediators following an allergic insult or patient ill health, drug intake or environmental exposure. We report on a ...
Giday Araya - - 2013
Evidence based clinical guidelines have provided clinicians with an increasing tool for management of hospitalized patients. However, large differences in the management of patients with acute coronary syndrome observed across the globe. To determine spectrum of severity, practice patterns and half-year outcomes of patients hospitalized with acute coronary syndrome in ...
Brenes Salazar Jorge A JA Department of Medicine, Division of Cardiovascular Diseases, Mayo Clinic, MN, - - 2013
Transient apical cardiomyopathy, also known as Takot-tsubo-like left ventricular dysfunction, is a clinical syndrome characterized by reversible left ventricular dysfunction at the apex with preserved basal contractility, in the setting of new ST and T wave changes suggestive of ischemia but no evidence of obstructive coronary artery disease on angiography. ...
Lim Joanna - - 2013
An 81 year old female patient diagnosed with a chronic low grade hypereosinophilic syndrome presented with angina and dyspnoea. She was managed for a non-ST elevated myocardial infarction since her troponin levels were elevated. On day 5, she suffered an acute clinical deterioration with type I respiratory failure and cardiogenic ...
Makki Nader - - 2013
Acute coronary syndrome (ACS) is a major health care and economic burden in the United States and accounts for more than 1 million hospitalizations annually. The morbidity and mortality due to ACS are substantial-nearly half of all deaths due to coronary heart disease occur following an ACS. This review provides ...
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