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Bang Casper N CN 1Department of Medicine, Weill Cornell Medical College, New York, NY; Department of Cardiology, The Heart Center, Rigshospitalet, Copenhagen, - - 2014
-Left ventricular (LV) hypertrophy (LVH, high LV mass) is traditionally classified as concentric or eccentric based on LV relative wall thickness. We evaluated the prediction of subsequent adverse events in a new 4-group LVH classification based on LV dilatation (high LV end-diastolic volume [EDV] index) and concentricity (LVM/EDV((2/3))) in hypertensive ...
Saini Shiv Sajan SS 1Neonatal Unit, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India. 2Department of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, - - 2014
We evaluated hemodynamic changes in preterm neonates with septic shock using functional echocardiography and studied the effects of vasoactive drugs on hemodynamic variables. Prospective observational study. Level III neonatal ICU. We enrolled 52 preterm neonates with septic shock (shock group) and an equal number of gestation and postnatal age-matched healthy ...
Ho Yuan-Chih YC 1Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. 2Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. 3Institute of Shock Wave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, - - 2014
We tested the hypothesis that, as compared with conventional door-to-balloon, shortened door-to-balloon time would further improve 30-day outcome in ST-elevation myocardial infarction (STEMI) patients undergoing primary stenting. Retrospective cohort study SETTING:: Academic tertiary care hospital with approximately 2600 beds PATIENTS:: Between January 2008 and December 2009, 266 ST-elevation myocardial infarction ...
Chen Xiang-Qi XQ Fujian Institute of Coronary Artery Disease and Department of Cardiology, Union Hospital, Fujian Medical University, Fuzhou, Fujian 350001, - - 2014
The aim of this study was to investigate whether the modification of bone marrow-derived mesenchymal stem cells (BMSCs) with the fused FGF4 (fibroblast growth factor 4)-bFGF (basic fibroblast growth factor) gene could improve the expression and secretion of BFGF, and increase the efficacies in repairing infarcted myocardium. We used in-Fusion ...
Asaad Nidal N Department of Cardiology, Heart Hospital, Hamad Medical Corporation , - - 2014
Objectives: To assess the impact of on-admission heart rate (HR) in patients presenting with acute coronary syndrome (ACS). Methods: Data were collected retrospectively from the second Gulf Registry of Acute Coronary Events. Patients were divided according to their initial HR into: (I: < 60, II: 60-69, III: 70-79, IV: 80-89 ...
Shehata M M Department of Cardiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt - - - 2014
Myocardial injury commonly occurs during percutaneous coronary intervention (PCI). Several agents that mimic ischemic preconditioning could help minimize this phenomenon. This study evaluated the cardioprotective role of intracoronary Adenosine in elective PCI. 100 diabetic patients with chronic stable angina were prospectively enrolled, then randomly assigned to undergo PCI with intracoronary ...
Xue Ling L Department of Cardiovascular Medicine, Qilu Hospital, Shandong University, No 107 Wenhua Xi Road, Jinan 250012, P.R. China; Department of Cardiovascular Medicine, Third Affiliated Hospital of Liaoning Medical College, Jinzhou 121000, Liaoning Province, - - 2014
To investigate the effect of salvianolic acid B on rats with myocardial ischemia-reperfusion injury. SD rats were randomly divided into five groups (n=10 in each group): A sham operation group, B ischemic reperfusion group model group, C low dose salvianolic acid B group, D median dose salvianolic acid B group, ...
Hu Qian Q Emergency Department, Fifth Affiliated Hospital of Zhengzhou University, Henan 450003, - - 2014
To explore protective effect of rosiglitazone on myocardial ischemia reperfusion injury. A total of 48 male SD rats were randomly divided into control group (A), I/R group(B), high dose of rosiglitazone (C), low dose of rosiglitazone (D). Plasm concentration of creatine kinase (CK), CK-MB, hsCRP, Superoxide dismutase (SOD), malondialdehyde (MDA), ...
Lavi Shahar S From the Western University (S.L., P.D., A.C., P.G., P.T., G.J., K.S., R.L.), London, Ontario, Canada; and London Health Sciences Centre (S.L., S.D., P.D., A.C., P.G., P.T., G.J., K.S., R.L.), London, Ontario, - - 2014
Remote ischemic preconditioning may result in reduction in infarct size during percutaneous coronary intervention (PCI). It is unclear whether remote ischemic postconditioning (RIPost) will reduce the incidence of myocardial injury after PCI, and whether ischemic conditioning of a larger remote organ (thigh versus arm) would provide further myocardial protection. We ...
Liu Chao C Department of Cardiac Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China, - - 2014
The purpose of this study was to determine the combined effect of transmyocardial laser revascularization (TMLR) and the implantation of endothelial progenitor cells (EPCs) on cardiac function of ischemic hearts in canines. The left anterior descending artery (LAD) was occluded to establish the canine model of acute myocardial infarct (AMI). ...
Ahn Sung Gyun SG Division of Cardiology, Yonsei University Wonju College of Medicine, Wonju, - - 2014
We aimed to investigate whether combination therapy using intracoronary (IC) abciximab and aspiration thrombectomy (AT) enhances myocardial perfusion compared to each treatment alone in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). We enrolled 40 patients with STEMI, who presented within 6 h of symptom onset ...
Yetimakman Ayse Filiz AF 1Department of Pediatrics, Istanbul Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, - - 2014
Objectives: Cardiology follow up is important in thalassemia major patients. The object of this study is to define parameters which can be used in the early detection of cardiac impairment. Material and Methods: Forty seven beta thalassemia major patients (mean age 16.3 ± 4.47 years; 22 boys, 25 girls) whose left ...
Lexis Chris P H CP University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the - - 2014
IMPORTANCE Metformin treatment is associated with improved outcome after myocardial infarction in patients with diabetes. In animal experimental studies metformin preserves left ventricular function. OBJECTIVE To evaluate the effect of metformin treatment on preservation of left ventricular function in patients without diabetes presenting with ST-segment elevation myocardial infarction (STEMI). DESIGN, ...
Peix Amalia A From the Institute of Cardiology, La Habana, - - 2014
The purpose of this study was to evaluate the ability of rest gated SPECT myocardial perfusion imaging (MPI) and intraventricular synchronism, to identify heart failure (HF) patients most likely to experience cardiac events. We studied 165 patients with left ventricular ejection fraction of less than 40%, who were divided in ...
Abe Daisuke D Department of Cardiology, Ibaraki Prefectural Central Hospital, Tomobe, - - 2014
There are a few retrospective subgroup analyses or registries of large-vessel (≥3.5mm) stenting. We investigated clinical outcomes of patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and bare-metal stents (BMS) in large coronary vessels. Of 1100 STEMI patients registered in the Ibaraki ...
Winchester David E DE Malcom Randall VA Medical Center, 1601 SW Archer Rd 111D, Gainesville, FL, 32608, USA, - - 2014
Inappropriate use of myocardial perfusion imaging (MPI) may vary depending on the training, specialty, or practice location of the clinician. We conducted a cross-sectional investigation of consecutive patients who underwent MPI at our Veterans Affairs medical center between December 2010 and July 2011. Characteristics of the MPI ordering clinicians were ...
Ueda Tomoya T First Department of Internal Medicine, Nara Medical University, Nara, - - 2014
Percutaneous coronary intervention (PCI)-related cardiac enzyme elevation is an independent risk factor for adverse clinical outcomes, but preprocedural predictors of this complication have not been established. This study evaluated the morphological characteristics of culprit lesions by frequency-domain optical coherence tomography (FD-OCT), and examined their predictive value for procedure-related myocardial injury ...
Shillcutt Sasha K SK Department of Anesthesiology, University of Nebraska Medical Center, Omaha, - - 2014
Patients with left ventricular diastolic dysfunction (LVDD) are at increased risk of postoperative adverse events. The primary aim of this study was to evaluate the safety and feasibility of using echocardiography-guided hemodynamic management (EGHEM) during surgery in subjects with LVDD compared to conventional management. The feasibility of using echocardiography to ...
Zhao Wei - - 2014
The importance of achieving complete revascularization by percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (MI) remains unclear. To compare short-term exercise capacity following acute ST-elevation myocardial infarction (STEMI), in patients receiving PCI with stenting, between those completely revascularized (CR) and those incompletely revascularized (IR). We retrospectively reviewed ...
Wang Tao T Department of Cardiology, The Fourth People's Hospital of Jinan, The Second Affiliated Hospital of Tai Shan Medical College, Jinan, - - 2014
The aim of this study was to test the hypotheses that epicardial adipose tissue (EAT) can be a marker of severe coronary artery disease in patients with acute myocardial infarction. Overall, 373 cases who underwent coronary angiography were classified into 2 groups by SYNTAX score: low-score and high-score group. EAT ...
Kurtul Alparslan A 1Department of Cardiology, Ankara Education and Research Hospital, Ankara, - - 2014
Low serum albumin (SA) levels are associated with increased cardiovascular mortality. We investigated whether baseline SA levels are associated with no-reflow following primary percutaneous coronary intervention (pPCI). A total of 536 patients (aged 60 ± 13 years; 74% men) who underwent pPCI were enrolled. The patients were divided into 2 ...
Liu Shuangmei S Department of Physiology, Medical School of Nanchang University, Nanchang 330006, - - 2014
Myocardial ischemia elicits a sympathoexcitatory response characterized by increase in blood pressure and sympathetic nerve activity. Puerarin, a major active ingredient extracted from the traditional Chinese plant medicine Ge-gen, has been widely used in treatment of myocardial and cerebral ischemia. However, little is known about the mechanism. Our study was ...
Hemayat Sevil S Faculty of Medicine, Islamic Azad University, Tehran, - - 2014
This study aimed at comparing the development of tricuspid and mitral regurgitation between the right ventricular outflow tract (RVOT) and right ventricular apex (RVA) pacing. We prospectively enrolled 164 patients for permanent pacemaker implantation due to sick sinus syndrome or atrioventricular block and randomly divided them into two equal groups ...
Jeong Hae Chang HC Chonnam National University - - 2014
The effects of statins on the prognosis of patients with left ventricular (LV) systolic dysfunction remain controversial. The aim of this study was to assess the effect of statin treatment on clinical outcomes in acute myocardial infarction (AMI) patients with LV systolic dysfunction. A total of 5,119 AMI patients with ...
Miyoshi Hirokazu H Cardiovascular Section, Higashi Tokushima Medical Center, National Hospital - - 2014
Previous studies have examined the negative impacts of individual cardiovascular risk (CVR) factors on left atrial (LA)-left ventricular (LV) interaction, whereas the combined effects of these risk factors are insuffi ciently elucidated. We studied 176 asymptomatic patients with CVR factors and age-matched 50 healthy individuals by conventional and 2-dimensional speckle-tracking ...
Miranda Douglas Pinheiro DP Post Graduation Program in Research and Development - Medical Biotechnology, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil, - - 2014
High intensity systematic physical training leads to myocardial morphophysiological adaptations. The goal of this study was to investigate if differences in training were correlated with differences in cardiac sympathetic activity. 58 males (19-47 years), were divided into three groups: strength group (SG), (20 bodybuilders), endurance group (EG), (20 endurance athletes), and ...
Sun Cheuk-Kwan CK Department of Emergency Medicine, E-DA Hospital, I-Shou University, Kaohsiung, - - 2014
This study tested whether adipose-derived mesenchymal stem cells (ADMSC) embedded in platelet-rich fibrin (PRF) scaffold is superior to direct ADMSC implantation in improving left ventricular (LV) performance and reducing LV remodeling in a rat acute myocardial infarction (AMI) model of left anterior descending coronary artery (LAD) ligation. Twenty-eight male adult ...
Tanındı Aslı A Department of Cardiology, Ufuk University Faculty of Medicine, Ankara, Turkey. - - 2014
Objectives: We investigated the relation between neutrophil to lymphocyte ratio (N/L) and the extent, severity, and complexity of coronary artery disease (CAD) and myocardial perfusion. Study design: One hundred and fifty-one patients who underwent coronary angiography with stable angina pectoris (SAP) (n=93) or acute coronary syndrome (ACS) (n=58) were included ...
Turgeman Yoav Y Heart Institute, H'aEmek Medical Center, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, - - 2014
We assess the epicardial and microcirculation flow characteristics, and clinical outcome by using catheter aspiration after each stage of primary percutaneous coronary intervention (PPCI). Conflicting data are reported regarding early and late benefit of using aspiration catheter in the initial phase PPCI. A total of 100 patients with ST-segment elevation ...
Kim Ji Won JW Department of Cardiovascular Medicine, Regional Cardiocerebrovascular Center, Wonkwang University Hospital, Iksan, - - 2014
High dose rosuvastatin loading before percutaneous coronary interventions (PCI) reduces the myocardial damage and the incidence of adverse cardiac events in patients with stable angina and acute coronary syndrome. However, no studies are present yet about rosuvastatin loading in patients with ST-segment elevation myocardial infarction (STEMI) in a primary PCI ...
Papai Gyorgy G Hungarian National Ambulance - - 2014
The efficacy of the transtelephonic ECG system (TTECG) in the management of ST segment elevation myocardial infarction (STEMI) was examined with regard to the ambulance service- and percutaneous coronary intervention (PCI)-related delay times, the prehospital medical therapy and the in-hospital mortality rate. The study was conducted as a collaborative effort ...
Assmus Birgit B Cardiology, Deptartment of Medicine III, Goethe University Frankfurt, Theodor-Stern-Kai 7, Frankfurt 60590, - - 2014
In the REPAIR-AMI trial, intracoronary infusion of bone marrow-derived cells (BMCs) was associated with a significantly greater recovery of contractile function in patients with acute myocardial infarction (AMI) at 4-month follow-up than placebo infusion. The current analysis investigates clinical outcome and predictors of event-free survival at 5 years. In the ...
Polizopoulou Zoe S ZS Diagnostic Laboratory, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, - - 2014
Cardiac troponin I (cTnI) is a biomarker correlated with the severity of myocardial injury. It is hypothesized that serial assessment of cTnI could provide information about the disease progression in chronic heart failure. The purpose of the study was to correlate serial serum cTnI concentrations with clinical scoring and select ...
Joffre Jérémie J Medical Intensive Care Unit, Cochin Hospital, Hôpitaux Universitaires Paris Centre, Assistance Publique des Hôpitaux de Paris, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Faculté de médecine, 15 rue de l'Ecole de Médecine, 75006 Paris, France; INSERM U970, Paris Cardiovascular Research Center (PARCC), European Georges Pompidou Hospital, 56 rue Leblanc, 75015 Paris, - - 2014
The leading cause of sudden cardiac death is myocardial ischemia. As for uncomplicated acute myocardial infarction (AMI), international guidelines plead for early coronary angiography with, in case of culprit lesion, angioplasty and stent implantation. However after cardiac arrest (CA), shock, hypothermia and changes in antiplatelet pharmacokinetic may promote stent thrombosis ...
Margonato Alberto A aCardiology and Coronary Intensive Care Unit bBone Metabolic Unit, Division of Cardiovascular Science, IRCCS S. Raffaele Hospital, Milan, - - 2014
To assess serum levels of the plaque calcification regulators osteoprotegerin (OPG) and Matrix Gla-proteins (MGP) in individuals with stable angina and acute myocardial infarction submitted to coronary angiography and their relation to coronary artery disease burden. The study included 40 individuals affected by ST-elevation myocardial infarction (STEMI) and 40 individuals ...
Manchurov Vladimir V Department of Cardiology, Moscow State University of Medicine and Dentistry, Moscow, - - 2014
Remote ischemic preconditioning (RIPC) by transient limb ischemia reduces myocardial ischemia-reperfusion injury in patients undergoing percutaneous coronary intervention (PCI). The aim of study we report here was to assess the effect of RIPC on endothelial function in patients with acute myocardial infarction (AMI) who underwent primary PCI. Forty eight patients ...
Ugur Murat M 1Clinic of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, - - 2014
The Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score (SS) was developed for evaluation of coronary artery disease complexity. We aimed to compare the SS calculated by conventional coronary angiography (CAG) and computed tomography angiography (CTA). Retrospectively, 107 patients were recruited (mean age 55.9 ± 12.4 ...
Conti Alberto A aAtrial Fibrillation Outpatient Clinic and Emergency Medicine bEmergency Medicine, Department of Critical Care Medicine and Surgery, cDysrhytmias Unit, Department of Cardiology, University of Florence, Careggi University Hospital, Florence, - - 2014
Patients with recent-onset atrial fibrillation (AF) and cardiac troponin I (cTnI) elevations show poor outcomes. Coronary heart disease might be a cause, consequence, or an innocent bystander. The aim of this study was to recognize and treat coronary heart disease to avoid adverse events. Patients with recent-onset AF participated in ...
Liu Yan-Li YL Department of Laboratory Medicine, Lianyungang Hospital Affiliated Bengbu Medical College, Lianyungang, Jiangsu 222006, P.R. - - 2014
When introduced into the infarcted heart, bone marrow‑derived mesenchymal stem cells (MSCs) prevent the heart from deleterious remodeling and improve its recovery. The aim of the present study was to investigate the effects of Ginkgo biloba extract (EGb) 761 on the infarcted myocardium microenvironment following MSC transplantation. The established rat ...
Fukunaga Masashi M From the Cardiovascular Division (M.F., K.F., D.K., H.S., K.M., H.T., T. Imanaka, T. Iwasaku, T.N., M.S., H.A., T.M.), Division of Coronary Heart Disease (M.M., M.O.), and Department of Radiology (K.K.), Hyogo College of Medicine, Nishinomiya, - - 2014
Despite a sufficient coronary blood flow after primary percutaneous coronary intervention for patients with ST-segment-elevation myocardial infarction; some patients have a poor outcome because of microcirculatory damage. This study evaluates whether the thermodilution-derived coronary blood flow parameters immediately after primary percutaneous coronary intervention predict early microvascular damage and midterm outcomes ...
Kwon Jin-Sook JS Research Laboratory of Cardiovascular Regeneration, Chonnam National University Hospital, Gwangju, - - 2014
We elucidated the therapeutic potential of human umbilical vein endothelial cells (HUVECs) for ameliorating progressive heart failure in a myocardial infarction (MI) rat model. MI was induced by ligation of left anterior descending artery, and HUVEC was transplanted 1week after MI. Cardiac function was evaluated by echocardiography, and histological analyses ...
Wardak Khalil S KS Broward County Medical Examiner and Trauma Services, 5301 S.W. 31st Avenue, Fort Lauderdale, FL, 33312, - - 2014
Drowning is a diagnosis of exclusion based on circumstantial and autopsy correlation. Sugimura proposed a threshold value of 14.1 for the Drowning Index (DI), the ratio of lung and pleural fluid to spleen weight, as a surrogate marker to diagnose drowning. We questioned the use of DI in diagnosing drowning. ...
Reddy Yeruva Madhu YM 1Division of Cardiovascular Diseases, Cardiovascular Research Institute, University of Kansas Hospital & Medical Center, Kansas City, - - 2014
-Data on relative safety, efficacy and role of different percutaneous left ventricular assist devices (pLVADs) for hemodynamic support during the ventricular tachycardia (VT) ablation procedure are very limited. -We performed a multicenter, observational study from a prospective registry including all consecutive patients (N=66) undergoing VT ablation with a pLVAD in ...
Chou Chu-Lin CL Institute of Medical Sciences, Tzu Chi University, Hualien, - - 2014
The outcomes of Chinese patients undergoing dialysis after coronary revascularization are unknown. We examined the outcomes of Taiwanese dialysis patients after coronary artery bypass grafting (CABG), percutaneous transluminal coronary angioplasty (PTCA), or coronary stenting. Using data from the National Health Institutes Research Database, we determined the outcomes of 1,287 dialysis ...
Türkmen Muhsin M aDepartment of Cardiology, Faculty of Medicine, Medipol University bDepartment of Cardiology, Kartal Kosuyolu Yuksek İhtisas Education and Research Hospital, Istanbul, - - 2014
The exact pathophysiology of slow coronary flow (SCF) phenomenon, characterized by delayed opacification of coronary arteries during coronary angiography, is still unknown, although endothelial dysfunction, inflammation, vasomotor disorders and atherosclerosis are shown. The present study was conducted to investigate whether there is a coagulation pathway abnormality in patients with SCF ...
Ma Jianying - - 2014
The objective of this study was to evaluate changes in left ventricular ejection fraction (LVEF) and left ventricular remodeling after coronary microembolization (CME) and to investigate the protective effects of methylprednisolone (MTP). CME was induced by injection of microspheres (42 mum Dynospheres) into left anterior descending artery of mini swine. ...
Nasseri Boris A BA Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, - - 2014
Intra-myocardial transplantation of CD133(+) bone marrow stem cells (BMC) yielded promising results in clinical pilot trials. We now performed the double-blinded, randomized, placebo-controlled CARDIO133 trial to determine its impact on left ventricular (LV) function and clinical symptoms. Sixty patients with chronic ischaemic heart disease and impaired LV function (left ventricular ...
Gokhroo R K RK Postgraduate Department of Cardiology, JLN Medical College & Associated Group of Hospitals, Ajmer 305 001, Rajasthan (India). - - 2014
Coronary sinus (CS) anatomy is a major predictor of successful implantation of left ventricular (LV) lead and procedural outcome. We therefore made an attempt to look at the CS anatomy and possible feasibility to classify them into categories depending upon their size, branching pattern, location of posterolateral vein (PLV), and ...
Lafci Gokhan G Departments of Cardiovascular Surgery (Drs. Kerim Cagli, Cicek, Diken, Gunertem, Lafci, and Yalcinkaya) and Cardiology (Drs. Kumral Cagli and Turak), Turkiye Yuksek Ihtisas Hospital, 06100 Ankara; Department of Cardiovascular Surgery (Dr. Korkmaz), Ankara Numune Education and Research Hospital, 06330 Ankara; and Department of Cardiovascular Surgery (Dr. Uzun), Ankara Education and Research Hospital, 06340 Ankara; - - 2014
Subvalvular apparatus preservation is an important concept in mitral valve replacement (MVR) surgery that is performed to remedy mitral regurgitation. In this study, we sought to determine the effects of papillary muscle repositioning (PMR) on clinical outcomes and echocardiographic left ventricular function in rheumatic mitral stenosis patients who had normal ...
Kishihara Jun J Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, - - 2014
We evaluated the effect of carvedilol, a beta-blocker with anti-oxidative action, against the atrial fibrillation (AF) inducibility, the development of atrial remodeling and the oxidative stress markers in a canine AF model. AF model was produced by performing 6-week rapid atrial stimulation in 15 dogs. The animals were divided into ...
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