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Portegies Marileen L P ML From the Department of Epidemiology (M.L.P.P., M.S., A.H., M.W.V., M.A.I.), Neurology (M.L.P.P., P.J.K., M.A.I.), Biomedical Engineering (M.S.), and Radiology (M.S., M.W.V.), Erasmus MC University Medical Center, Rotterdam, The - - 2014
Left-sided strokes are reported to be more common than right-sided strokes, but it is unknown whether they occur more often or are simply recognized more easily by clinicians. In a large unselected community-dwelling population, we examined the frequency of clinical left- and right-sided strokes and transient ischemic attacks (TIAs) and ...
Chiang Sharon S Department of Statistics, Rice University, Houston, TX, - - 2014
To investigate lateralized differences in limbic system functional connectivity between left and right temporal lobe epilepsy (TLE) using graph theory. Interictal resting state fMRI was performed in 14 left TLE patients, 11 right TLE patients, and 12 controls. Graph theory analysis of 10 bilateral limbic regions of interest was conducted. ...
Liu Yan Y Department of Geriatrics, The First Hospital of Shijiazhuang City, Shijiazhuang, Hebei 050011, P.R. - - 2014
The aim of the present study was to investigate the effects of spironolactone and losartan on the early healing stage of acute myocardial infarction (AMI) in rats. An AMI rat model was established and the rats were randomly divided into four groups: AMI (n=12), AMI + spironolactone (AMI + S; ...
Jiang Yiyao Y Department of Cardiovascular Surgery, TEDA International Cardiovascular Hospital Cardiovascular Clinical Hospital of Tianjin Medical University, 61# Third Avenue Tianjin Economic Development Area, Tianjin, 300457, - - 2014
Hypoxic preconditioning is a promising method for improving the anti-apoptotic and paracrine signaling capabilities of adipose-derived stromal cells (ADSCs). The purpose of this study was to analyze the influence of different hypoxic conditions on ADSCs and the therapeutic effects of hypoxia-preconditioned ADSCs (HPADSCs) on an animal model of myocardial infarction ...
van Loon Ramon B - - 2014
Viability seems to be important in preventing ventricular remodeling after acute myocardial infarction (AMI). We investigated the influence of viability, as demonstrated with low-dose dobutamine echocardiography, and the role of early revascularization on the process of left ventricular (LV) remodeling after AMI. We retrospectively investigated 224 patients who were initially ...
Sakurai Shigeru S Department of Cardiovascular Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, - - 2014
To examine the effects of cariporide, a Na(+)/H(+) exchanger-1 inhibitor, on cardiac norepinephrine (NE) and myoglobin releases during myocardial ischemia/reperfusion by applying a microdialysis technique to the rabbit heart. In anesthetized rabbits, two dialysis probes were implanted into the left ventricular myocardium and were perfused with Ringer's solution. Cariporide (0.3mg/kg) ...
Kurtul Alparslan A Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey - - 2014
We investigated whether admission estimated glomerular filtration rate (eGFR) values are associated with no-reflow phenomenon in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Patients (n = 673; 59 ± 13 years; 77.1% men) were stratified into 3 groups according to eGFR at admission: ...
Caliskan Zuhal Z Baskent University, Konya Teaching and Medical Research Center, Gastroenterology Department, Konya, Turkey. Electronic address: - - 2014
Increased incidence of coronary vascular events in patients with inflammatory bowel disease (IBD) is known. However, the association between coronary microvascular function and IBD has not been fully defined. We aimed to investigate whether coronary flow reserve (CFR) and left ventricular diastolic function were impaired in IBD patients. Seventy-two patients ...
Börekçi Abdurrezzak A Department of Cardiology, School of Medicine, Kafkas University, Kars, - - 2014
In the pathogenesis of atherosclerosis, oxidative stress plays a major role in plaque instability, rupture, and erosion, which subsequently leads to thrombus formation and causes total infarct-related artery (IRA) occlusion. We investigated the relationship between spontaneous reperfusion (SR) of IRA and oxidative stress in patients with anterior ST-segment elevation myocardial ...
Pappone Carlo C Department of Arrhythmology, Maria Cecilia Hospital, GVM Care & Research, Cotignola, - - 2014
Cardiac resynchronization therapy (CRT) with multipoint left ventricular (LV) pacing (MPP) in a single coronary sinus branch improves acute LV function. We hypothesized that MPP can improve mid-term echocardiographic and clinical response compared with conventional CRT. Consecutive patients receiving a CRT implant (Unify Quadra MP™ or Quadra Assura MP™ CRT-D ...
Zhang Wei W Department of Neurology, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China, - - 2014
Provide the basis for clinical pathogeny diagnosis and discuss effective ways of curing the youth cerebral infarction in different TOAST classifications through analysis of the correlation between the youth infarction in different TOAST classifications and high homocysteine (Hcy). The selected young patients who diagnosed with cerebral infarction and admitted to ...
Kim Ung U Division of Cardiology, Yeungnam University Medical - - 2014
This study evaluated the clinical impact of Q-wave presence on ECG at presentation of patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).From April 2005 to September 2009, 184 consecutive STEMI patients who underwent primary PCI within 12 hours of chest pain onset were retrospectively evaluated. ...
Agoston Gergely - - 2014
Cardiac involvement is a relevant clinical finding in systemic sclerosis (SSc) and is associated with poor prognosis. Left atrial (LA) remodeling and/or dysfunction can be an early sign of diastolic dysfunction. Two-dimensional speckle tracking echocardiography (STE) is a novel and promising tool for detecting very early changes in LA myocardial ...
Petrucci Ettore E Cardiologia Interventistica, Ospedale di Busto Arsizio, Busto Arsizio, Italy. Electronic address: - - 2014
This study aimed to determine whether the intracoronary electrograms (IC-EGMs) recorded using a standard percutaneous coronary intervention guidewire could provide myocardial viability information. The revascularization of dysfunctional but viable myocardium may confer prognostic benefits compared with medical therapy in patients with post-ischemic heart failure. However, knowledge of myocardial viability is ...
Mostafa Mostafa S MS 1Department of Nuclear medicine,Assiut - - 2014
Background: Coronary artery lesions in Kawasaki disease invasively assessed by coronary angiography. Evaluation of myocardial perfusion by single-photon emission computed tomography may identify the haemodynamic significance of coronary lesions. Objective: To evaluate diagnostic accuracy of dipyridamole stress technetium-99 m tetrofosmin, single-photon emission computed tomography as a possible alternative to invasive ...
Wang Wenru W National University of Singapore, Singapore - - 2014
This cross-sectional correlational study aimed to examine health-related quality of life (HRQoL) and its predictors among patients with myocardial infarction (MI). One hundred and twenty-eight outpatients with MI were recruited from a university hospital. The 12-item Short-Form Health Survey version 2, Myocardial Infarction Dimensional Assessment Scale (MIDAS), and Hospital Anxiety ...
Jablonowski Robert R Department of Radiology and Biomedical Imaging, School of Medicine, University of California San Francisco, 185 Berry St, Suite 350, Campus Box 0946, San Francisco, CA - - 2014
To measure and validate patchy and large myocardial infarction (MI) at 3 days and 5 weeks in beating and nonbeating hearts using contrast-enhanced three-dimensional (3D) inversion-recovery gradient echo (IR-GRE) magnetic resonance imaging (MRI) and microscopy. Pigs (n = 28) were subjected to 1) patchy MI (group I), 2) large MI (group II), or 3) ...
Sakamoto Ayami A 1 All authors: Department of Radiology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, - - 2014
OBJECTIVE. The purpose of this study was to evaluate the usefulness of quantification of lung perfused blood volume (PBV) with dual-energy CT (DECT) for assessment of the severity of acute pulmonary thromboembolism (PTE). MATERIALS AND METHODS. We retrospectively analyzed the records of 72 patients with PTE and 168 without PTE ...
Demeure Fabian F From the Pôle de Recherche Cardiovasculaire (CARD), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, Brussels, - - 2014
(18)F-FDG PET/CT can be used to detect arterial atherosclerotic plaque inflammation. However, avid myocardial glucose uptake may preclude its use for visualizing coronary plaques. Fatty acid loading or calcium channel blockers could decrease myocardial (18)F-FDG uptake, thus assisting coronary plaque inflammation identification. The present prospective randomized trial compared the efficacies ...
Guerchicoff Alejandra A Cardiovascular Research Foundation, New York, NY, - - 2014
Objectives: Contrast-induced acute kidney injury (CI-AKI) may occur after percutaneous coronary intervention (PCI). We sought to evaluate patients with ST-elevation myocardial infarction (STEMI) undergoing emergency PCI and evaluated their risk for CI-AKI. Methods: Serum biomarkers were measured in patients who provided specific written informed consent for blood withdrawal at baseline, ...
Basili Stefania S From the I Clinica Medica (S.B., V.R., P.P., R.C., F.V.), Department of the Heart and Great Vessels Attilio Reale (G.T., C.C., F.B., E.M.), and Department of Public Health and Infectious Diseases (A.F.), Sapienza-University of Rome, Rome, Italy; and Division of Cardiology, Department of Interventional Cardiology, Santa Maria University Hospital, Terni, Italy (M.D., A.P., A.A.). - - 2014
Microvascular obstruction seems to predict poor outcome in patients undergoing elective percutaneous coronary intervention (PCI), but the underlying mechanism is still unclear. We analyzed whether serum thromboxane B2, a stable metabolite of thromboxane A2, may be implicated in post-PCI microvascular obstruction. We enrolled 91 patients (74 males, 66±10 years) on ...
Jiang Changhao C Department of Cardiology, Yiwu Hospital of Wenzhou Medical University (Yiwu Central Hospital), Yiwu, 322000, Zhejiang, People's Republic of China, - - 2014
Our objective was to explore the effects of miR-92a and miR-126 on myocardial apoptosis in mouse ischemia-reperfusion model and further investigate the underlying mechanisms. Eighteen Kunming mice were selected and randomly divided into sham operation group and ischemia-reperfusion group with nine mice in each group. Cardiac muscle tissue was stained ...
Huang Zhi-Bin ZB Department of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, - - 2014
This study investigated the effects of fosinopril on the electrophysiological characteristics of the left ventricular hypertrophic myocardium in spontaneously hypertensive rats (SHRs). Twenty-four 10-week-old male SHRs were divided into fosinopril and non-fosinopril groups (n = 12 each). Twelve 10-week-old Wistar-Kyoto rats were used a control group. Left ventricular mass index and ventricular ...
Miyoshi Hirokazu H Cardiovascular Section, Higashi Tokushima Medical Center, National Hospital Organization , Tokushima , Japan - - 2014
Abstract Left atrial (LA) structural and functional abnormalities are vital steps on the pathway toward heart failure with preserved ejection fraction in asymptomatic patients. The purpose of this study was to assess the relationship of LA function, particularly reservoir function, with LA structural remodeling related to the left ventricular (LV) ...
Gamou Tadatsugu T Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, - - 2014
The occurrence of deteriorated coronary flow associated with distal embolization during percutaneous coronary intervention results in impaired myocardial perfusion and worsens the clinical prognosis. This study aimed to examine the impact of optical coherence tomography (OCT)-determined coronary plaque morphology on the prediction of deteriorated coronary flow after stent implantation in ...
Guo Chun-Yu CY Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, - - 2014
To explore the effects of Panax Quinquefolium Saponin (PQS) on phosphatidylinositol 3-kinase/serine threonine kinase (PI3K/Akt) pathway of neonatal rat myocardial cells subjected to hypoxia. Neonatal rat myocardial cells were cultured in vitro. After the myocardial cell injury was induced by hypoxia, the cells were randomized into 5 groups: the normal ...
Kongoji Ken K Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, 216-8511, - - 2014
We evaluated the influence of early defects (EDs) in the infarcted myocardium after reperfusion, detected by computed tomography angiography (CTA), on cardiac function and exercise capacity in the chronic phase. We retrospectively analyzed 48 acute myocardial infarction (AMI) patients who underwent both CTA using 64-slice multidetector CT within 14 ± 6 days and ...
Song Pil Sang PS Division of Cardiology, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Corea del - - 2014
It is uncertain whether side branch predilatation before main vessel stenting is necessary. We evaluated the effect of side branch predilatation on outcomes in percutaneous coronary intervention for true nonleft main bifurcation determined by the Medina classification using the provisional approach. Target vessel failures (composite of cardiac death, myocardial infarction, ...
Niazi Imran I Aurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke's Medical Centers, University of Wisconsin School of Medicine and Public Health, 2801 W. Kinnickinnic River Parkway, #840, Milwaukee, 53215, WI, USA, - - 2014
Left ventricular (LV) electrical activation pattern could determine optimal LV lead placement site during cardiac resynchronization therapy (CRT) device implant. We sought to determine the feasibility of using EnSite NavX™ electroanatomic mapping system (St. Jude Medical Inc., St. Paul, MN) to assess LV electrical activation during CRT implant. Patients (n = 32; ...
Yang Li L Department of Cardiology, Sun Yat-Sen Memorial Hospital, Sun Yet-Sen University, 107 Yanjiang West Road, Guangzhou, 510120, China, - - 2014
To study left atrial deformation characteristics using Velocity vector imaging (VVI) in hypertensive patients with and without left ventricular hypertrophy (LVH), and to explore its value for detection of left atrial dysfunction in these patients. Sixty-four patients with essential hypertension were divided into normal left ventricular geometry (LVN, 37 cases) ...
Gruzdeva Olga - - 2014
Free fatty acids (FFA), oxidized low-density lipoprotein (LDL) and its antibodies, lipid profile markers, which are formed under oxidative stress, play an important role in atherosclerotic disease. Assess the levels of these markers in myocardial infarction patients depending on the extent of coronary artery disease (CAD). ST-elevation MI patients with ...
Ma Kai K Pediatric Cardiac Surgery Center, National Center for Cardiovascular Disease and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, - - 2014
To determine outcomes of patients presenting with an anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) who underwent coronary transfer, and to investigate the role of the left ventricular ejection fraction (LVEF) and preoperative myocardial viability as the predictors for incomplete LV functional recovery. From 2002 ...
Akgul Ozgur O Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Istanbul, - - 2014
The aim of this study was to evaluate the prognostic value of fragmented QRS (fQRS) on electrocardiography (ECG) patients with acute ST-segment elevation in myocardial infarction (STEMI), who are undergoing primary percutaneous coronary intervention (PCI). We prospectively enrolled 414 consecutive STEMI patients (mean age of 55.2 ± 12.2 years old, ...
Yarbrough William M WM Sisters of Charity Providence - - 2014
Historically, the tissue inhibitors of matrix metalloproteinases were considered monochromatic in function. However, differential TIMP profiles more recently observed with left ventricular dysfunction and matrix remodeling suggest more diverse biological roles for individual TIMPs. This study tested the hypothesis that cardiac specific overexpression (TIMP-4OE) or deletion (knockout; TIMP-4KO) would differentially ...
Qian Yuanyu Y Department of Emergency, Chinese PLA General Hospital, Beijing 100853, P.R. - - 2014
In the present study, the effect of initial body temperature changes on myocardial enzyme levels and cardiac function in acute myocardial infarction (AMI) patients was investigated. A total of 315 AMI patients were enrolled and the mean temperature was calculated based on their body temperature within 24 h of admission ...
Lu Xiao-Mei XM Department of Pathophysiology, College of Basic Medical Sciences, China Medical University, Shenyang, Liaoning 110001, P.R. - - 2014
The aim of the present study was to investigate the effect of olmesartan medoxomil (OLM) on renal injury in mice with myocardial infarction (MI). A total of 33 male C57/BL/6 mice were divided into a sham surgery group (SHAM group), MI group (MI group) and OLM treatment group (OLM group). ...
Cheng Rongchao R Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Heilongjiang Province, - - 2014
Coronary flow reserve (CFR) in the non-infarcted myocardium is often impaired following acute myocardial infarction (AMI). However, the clinical significance of CFR in the non-infarcted myocardium is not fully understood. The objective of the present study was to assess whether a relationship exists between CFR and left ventricular remodeling following ...
Yang Fengyong F ICU, Affiliated Hospital of Qingdao University, 21 Jiangsu Road, Qingdao, 266000, - - 2014
The aim of the study was to evaluate the clinical efficacy of hydrogen sulfide (H2S) treatment on the endothelin-induced cardiac hypertrophy. Sixty-four adult male rats, weighing from 180 to 200 g, were randomly divided into four groups: ten in normal group, ten in sham group, 44 in model group established by ...
Liu Q Q Department of Emergency Medicine, People's Hospital of Zhengzhou, Zhengzhou, Henan Province, China. - - 2014
To explore the heart protection effects by RNA interference of Caspase-3 on rat acute myocardial infarction (AMI). 45 SD rats were randomly divided into sham group, AMI group and Caspase-3-siRNA group. Animal model of AMI was established by ligation of anterior descending branch (LAD). Rats of sham operation group and ...
Choi Yun Ha YH 0000-0002-0224-0062 The Division of Cardiology, Chonnam National University Hospital, Gwangju, Korea. ; College of Nursing, Chonnam National University, Gwangju, - - 2014
The aim of this study was to evaluate the relation between neutrophil-to-lymphocyte ratio (NLR) and plaque components assessed by virtual histology-intravascular ultrasound in 399 coronary artery disease (CAD) patients with 471 coronary lesions. We classified the lesions into two groups according to the NLR on admission {low NLR group (NLR≤2.73 ...
Wang Xiang X Department of Cardiology, Shanghai First People's Hospital, Affiliated Shanghai Jiaotong University, Shanghai, 200080, - - 2014
The efficacy of post-percutaneous coronary intervention (PCI) intracoronary injection with bone marrow mesenchymal stem cells (BMSCs) in patients with acute myocardial infarction (AMI) remains controversial. Here, 58 patients with AMI undergoing PCI were randomly divided into two groups: BMSC and control groups. Autologous BSMCs were then generated in vitro from ...
Di Mauro Michele M Department of Adult Cardiac Surgery, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia Department of Cardiology, University of L'Aquila, L'Aquila, - - 2014
The aim of this study was to evaluate 17-year actual clinical outcomes of patients undergoing coronary artery bypass graft (CABG) using skeletonized versus pedicled bilateral internal mammary arteries (BIMAs). From September 1991 to June 1996, 548 consecutive patients underwent CABG for multivessel disease using BIMA. After propensity matching, 350 patients ...
Cetin Mustafa M aDepartment of Cardiology, School of Medicine, Adiyaman University, Adiyaman bDepartment of Cardiology, Kahramanmaras State Hospital, Kahramanmaras, - - 2014
Coronary collaterals may be insufficient for restoring blood flow to normal levels in patients with chronic total occlusions (CTO), leading to myocardial ischemia and electrical inhomogeneity in the ventricles. We evaluated the effect of percutaneous CTO revascularization on parameters of ventricular repolarization, including the T wave peak-to-end interval (TpTe) interval, ...
Kim Kyung Hwan KH Division of Cardiology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, Republic of - - 2014
The CHA2DS2VASc score has been used to evaluate the risk of thromboembolic events in atrial fibrillation. However, because all the components of CHA2DS2VASc are important cardiovascular risk factors, we decided to evaluate the effectiveness of CHA2DS2VASc score as a long-term predictor for prognosis in acute myocardial infarction (AMI) patients. We ...
Zhang She-Qing SQ Department of Neurology, Changhai Hospital, Second Military Medical University, Shanghai, - - 2014
Anticoagulants are commonly used to treat ischemic stroke. Its impact on cerebellar infarction has not been fully understood. In the clinical study, we reviewed a consecutive series of patients with large-sized cerebellar infarction (diameter > 3 cm, n = 30) treated with or without anticoagulation. In animal study, cerebellar infarction operation was performed in 12 ...
Liao Kai K Department of Cardiology, Renmin Hospital of Wuhan University and Cardiovascular Research Institute of Wuhan University, P.R. - - 2014
: Electrical carotid baroreceptor stimulation (CBS) has shown therapeutic potential for resistant hypertension and heart failure by resetting autonomic nervous system, but the impacts on arrhythmias remains unclear. The present study evaluated the effects of CBS on ventricular electrophysiological properties in normal dog heart and arrhythmias following acute myocardial infarction ...
Watabe Taichi T The Second Department of Internal - - 2014
Unnecessary ventricular pacing in sinus node disease (SND) must be avoided. To test the hypothesis that in SND, with or without 1(st) degree atrioventricular (AV) block, cumulative percent ventricular pacing (cum%VP) can be limited by low right atrial septal (LRAS) instead of right atrial appendage (RAA) pacing. We studied 102 ...
Joukar Siyavash S Physiology Research Center, School of Medicine, Kerman University of Medical Sciences, Kerman, - - 2014
Objective: We aimed to assess the influence of Melissa officinalis (lemon balm), a well-known herbal drug with numerous applications in traditional and modern medicine, on cardiac conduction and susceptibility to lethal ventricular arrhythmia. Materials and Methods: Forty-two male Wistar rats were divided into a control group (CTL), an M. officinalis ...
Bai Min-Fu MF Department of Cardiology, Zhengzhou University People's Hospital, Zhengzhou, - - 2014
Abnormal thyroid hormone metabolism influences the occurrence and progress of coronary heart disease (CHD). The aim of the present study was to analyze the severity of coronary artery lesions and the prognosis of thyroid dysfunction patients admitted for coronary angiography (CAG). From July 2011 to July 2012, 605 consecutive patients ...
Ding X X Department of Cardiology, Changhai Hospital, 2nd Military Medical University, 168 Changhai Road, 200433, Shanghai, PR - - 2014
The aim of this study was to investigate whether renal sympathetic denervation (RSD) is more effective on myocardial hypertrophy than the angiotensin-converting enzyme inhibitor (ACEI) perindopril in spontaneously hypertensive rats (SHRs). After bilateral renal denervation blood pressure (BP) was measured every 10 days. On day 50 the heart was (histo)pathologically examined. ...
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