Search Results
Results 251 - 300 of 2033
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Wang J J Department of Cardiology, The First Hospital of China Medical University, Shenyang 110001, - - 2013
To discuss the positive rate of ventricular late potential (VLP) between patients with acute ST-segment elevation myocardial infarction (STEMI) and patients with acute non NSTEMI. One hundred and sixty-three cases of acute myocardial infarction (90 patients with STEMI and 73 with NSTEMI), admitted to the First Hospital of China Medical ...
Ibrahim O O O. Ibrahim, Department of Medicine, University Kebangsaan Malaysia Medical Centre, Cheras 56000, Kuala Lumpur, - - 2013
To determine the prevalence of aspirin resistance and associated risk factors based on biochemical parameters using whole blood multiple electrode aggregometry. The study was conducted at the outpatients cardiology clinic of the Universiti Kebangsaan Malaysia Medical Centre (UKMMC) from August 2011 to February 2012. Subjects on aspirin therapy were divided ...
Bibli Sofia-Iris - - 2013
Chronic skeletal muscle ischemia protects the ischemic heart by preserving coronary flow and inducing arterioangiogenesis. We sought to determine the effect and the underlying molecular mechanisms of preconditioning (PreC) and postconditioning (PostC), applied in a model of chronic skeletal muscle ischemia. Male rabbits were divided into 3 series. In each ...
Kong Feng F Central Research Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. - - 2014
The aim of the present study was to investigate the protective effect of baicalin (BA) against ischemia-reperfusion (I/R) injury in isolated rat hearts. Sprague-Dawley rat hearts were rapidly removed, mounted on a Langendorff apparatus and subjected to 30 min ischemia followed by 30 min reperfusion with Krebs-Henseleit (K-H) solution at ...
Sonne Carolin - - 2013
There is little consensus on optimal atrioventricular (AV) and ventricular-to-ventricular (VV) intervals in cardiac resynchronization therapy (CRT). The aim of this study was to examine a novel combination of Doppler echocardiography (DE) and three-dimensional echocardiography (3DE) for individualized AV- and VV-interval optimization compared to conventional electrocardiogram (ECG) optimization. In this ...
Kholmukhamedov Andaleb A Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South - - 2014
Recent studies suggest that an increase in apoptosis within the myocardium may be a contributing factor for the progression of late adverse left ventricular (LV) remodeling following myocardial infarction (MI). Given that apoptosis is often triggered by induction of the mitochondrial permeability transition (MPT) pore, the goal of this study ...
Baktir Ahmet Oguz - - 2013
The relationship between extent, severity, and complexity of coronary artery disease (CAD) in patients with ST-segment elevation myocardial infarction (STEMI) and serum γ-glutamyl transferase (GGT) activity has not been adequately studied. We evaluated the relationship between GGT activity and the burden of CAD as assessed by SYNTAX score (SXscore) in ...
Pan Guangwei - - 2013
Few data exist about the effect of cardiac resynchronization therapy (CRT) on left atrial (LA) reverse remodeling and function, and whether echocardiographic (echo)-guide pacemaker optimization of atrioventricular and interventricular delays could beneficially affect LA reverse remodeling in long-term CRT therapy. Effect of periodic pacemaker optimization on LA reverse remodeling induced ...
Fournier Stephane - - 2013
Objectives: To test if the time of day significantly influences the occurrence of type 4A myocardial infarction in elective patients undergoing percutaneous coronary intervention (PCI). Background: Recent studies have suggested an influence of circadian rhythms on myocardial infarction size and mortality among patients with ST-elevation myocardial infarction. The aim of ...
Kaya Mehmet Gungor - - 2013
The effect of β-blockage on cardiac dyssynchrony in idiopathic dilated cardiomyopathy (IDC) is unknown. This study evaluated the impact of carvedilol and metoprolol succinate on left ventricular (LV) dyssynchrony and reverse remodeling in IDC. In this small, prospective, double-blind study, we randomly assigned 81 IDC patients to receive carvedilol or ...
Tonon Jair - - 2013
Although cardiac muscle hypertrophy has been studied in association with several diseases, its mechanism in patients with emphysema, in particular in relation to oxidative stress and proteolysis, remains unknown. The role of oxidative stress and proteolysis in right and left ventricle hypertrophy was investigated in hamsters with emphysema induced by ...
Raffay Violetta - - 2013
Cardiac arrest is a daunting medical emergency. The aim of the present study was to assess whether the combination of adrenaline and glucagon would improve initial resuscitation success, 48-hour survival, and neurologic outcome compared with adrenaline alone in a porcine model of ventricular fibrillation. Ventricular fibrillation was induced in 20 ...
Zhao Qifeng - - 2013
This study aims to determine the effect of Lipoxin (LX)A4 on myocardial ischemia reperfusion injury (MIRI) in rats and the related molecular mechanisms. Male SD rats were divided into six groups. The sham operation groups (groups C1, C2) were injected with 2 ml/kg normal saline before and after coronary artery ...
Häggström J - - 2013
Pimobendan and benazepril are frequently used with diuretics to treat dogs in congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD). To compare the short-term effects of pimobendan versus benazepril on pump function, heart size, and neuroendocrine profile in dogs with CHF caused by MMVD. Sixteen client-owned dogs. ...
Braggion-Santos M F - - 2013
Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) enables high-resolution myocardial tissue characterization, showing the results of different injuries, especially in the early period after heart transplantation (HTX). We sought to apply LGE-CMR to investigate the prevalence and patterns of infarct-atypical myocardial involvement and associated mechanisms in patients early and late ...
Benedek Imre - - 2013
Aim: To assess the long-term effects of intracoronary stem cell (SC) infusion following acute myocardial infarction (AMI) on the local atherosclerotic process at the site of infusion after four years of follow-up. Methods: We evaluated 18 post-AMI patients. Group 1 consisted of nine patients given an intracoronary injection of autologous ...
Chung Seungmin - - 2013
We sought to determine the relationship between white blood cell count (WBCc) and infarct size assessed by cardiovascular magnetic resonance imaging (CMR) in patients undergoing primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). In 198 patients undergoing primary PCI for STEMI, WBCc was measured upon arrival and CMR ...
Betensky Brian P - - 2013
-Identification of intramural basal-septal ventricular tachycardia (VT) substrate is challenging in nonischemic cardiomyopathy (NICM). We sought to: 1) Characterize normal/abnormal (NICM) transseptal RV to LV activation; 2) Assess the effect of "opposite" RV pacing on LV septal bipolar electrograms (EGMs); and 3) Establish criteria for identification of intramural septal VT ...
Tasal Abdurrahman - - 2013
We assessed the association between serum cystatin C (CysC) levels and coronary slow flow (CSF) phenomenon in patients who underwent coronary angiography. A total of 210 patients (mean age 55.6 ± 10.9 years; 100 females) were included. Patients were divided into 3 groups, (patients with CSF [group 2], with coronary ...
Ali Ola Sayed - - 2013
It is known that xanthine oxidoreductase contributes significantly to ischemia/reperfusion injury by generating reactive oxygen species. Ischemia-modified albumin (IMA) is a biomarker of acute myocardial ischemia with high sensitivity but moderate specificity. Our study aims to evaluate the xanthine oxidase (XO) system and the IMA level in the serum of ...
Alsaab Ayham - - 2013
Inversion of the T waves (T-) in electrocardiographic leads with ST-segment elevation after the initiation of reperfusion therapy is considered a sign of reperfusion. However, the significance of T- on presentation before the initiation of reperfusion therapy is unclear. The aim of this study was to assess whether T- on ...
Veselka Josef - - 2013
The first alcohol septal ablation was performed almost 20 years ago in 1994; since then it has become a widely used technique for the treatment of highly symptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM). It has been shown that postprocedural basal septal shrinking as a result of myocardial scarring is ...
Zhu Xin-Yuan - - 2013
The decoction of American Ginseng and Corydalis Tuber has been widely used for treatment of cardiovascular diseases due to their anti-ischemic and anti-arrhythmic effects. To evaluate the anti-apoptotic effect of Shenyuan, which is composed of the bioactive components extracted from the mixture of American Ginseng and Corydalis Tuber, and to ...
Patel Jigar H - - 2013
The influence of the presenting electrocardiographic (ECG) findings on the treatment and outcomes of patients with non-ST-segment elevation myocardial infarction (NSTEMI) has not been studied in contemporary practice. We analyzed the clinical characteristics, in-hospital management, and in-hospital outcomes of patients with NSTEMI in the Acute Coronary Treatment and Intervention Outcomes ...
Ohya Hidefumi - - 2013
Provisional crossover stenting has the potential risk of side-branch (SB) compromise, which may result in periprocedural myocardial infarction. Predilatation is a useful technique to prevent SB compromise. The aim of this study was to assess the safety and efficacy of predilatation using the kissing-balloon technique (preKBT) during provisional crossover stenting ...
Dwyer Nathan B - - 2013
Postconditioning is a potential cardioprotective strategy that has demonstrated conflicting and variable reductions in infarct size in human trials. To determine whether postconditioning could increase the extent of myocardial salvage in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (PPCI). One hundred two patients (aged 57 ± 11 ...
Zhang Dongfang - - 2013
In clinical practice, Epimedii Herba and Ginkgo Folium preparations are widely used in treatment of diseases such as coronary heart disease (angina) in China. However, there are no studies on the two-drug combination. To explore the effect of the mixture of the Epimedii Herba extract (EE) and Ginkgo Folium extract ...
Zhang Jia-Qiang - - 2013
Both ischemic preconditioning (IPC) and limb remote ischemic postconditioning (LRIPOC) have been shown to possess significantly different cardioprotective effects against the myocardial ischemia reperfusion injury (IRI), but no study has compared the anti-inflammatory effects of IPC and LRIPOC during myocardial IRI process. We hypothesized that IPC and LRIPOC would produce ...
Berry Colin - - 2013
In patients with acute non-ST-elevation myocardial infarction (NSTEMI), coronary arteriography is usually recommended; but visual interpretation of the angiogram is subjective. We hypothesized that functional assessment of coronary stenosis severity with a pressure-sensitive guide wire (fractional flow reserve [FFR]) would have additive diagnostic, clinical, and health economic utility as compared ...
Feng Chao - - 2013
Objective Our study focused on acute lacunar infarct shapes to explore the risk factors and clinical significance of irregularly shaped lacunar infarctions. Methods Based on the shape of their acute lacunar infarct, patients (n=204) were classified into the "regular" group or "irregular" group. The characteristics of the lacunar infarction were ...
Radulescu D D University of Medicine and Pharmacy "Iuliu Hatieganu", 5th Medical Hospital, Department of Cardiology, Cluj-Napoca, - - 2013
Purpose: The aim of this study was to assess whether treatment with angiotensin converting enzyme inhibitors (ACEI) can prevent the alteration of left ventricular systolic and diastolic performance in cancer patients treated with different chemotherapy regimens containing epirubicin. Methods: In this prospective study , 68 patients with different malignant tumors ...
Kim Kyung Hwan KH Division of Cardiology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, - - 2013
The high-sensitivity C-reactive protein (hs-CRP), a marker of inflammation, has been known to be elevated in patients with coronary artery disease. However, there is controversy about the predictive value of hs-CRP after acute myocardial infarction (MI). Therefore, we evaluated the impact of ischemic time on the predictive value of hs-CRP ...
Yoon Namsik N Department of Cardiology, Chonnam National University Hospital, Gwangju, - - 2013
It is widely known that angiotensin-II receptor blockers (ARBs) have reverse remodeling effects in atrium. Although atrial fibrillation is frequent in ischemic heart failure clinically, experiments to demonstrate ARB's effects on atrial remodeling in a heart failure model are rare. A heart failure model and a sham-operated group were formed ...
Al-Amran Fadhil G FG MD FRCS FACS, Surgical Department, Medical College, Kufa University, Najaf, - - 2013
To investigate the effects of two different sets of graft temperature during perfusion on myocardial protection in the immediate post transplantation period in rats. RATS GROUPED INTO: Sham and two study groups, which include two set groups of heterotopic heart transplant perfused at two different temperature set. The studied groups ...
Salgado Filho Marcello Fonseca - - 2013
To evaluate the rates of mortality and morbidity in patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) using routine intraoperative transesophageal echocardiography (ITEE). We conducted a retrospective, observational review of medical records of 360 patients from April 2010 to April 2012. We analyzed: age, weight, height, gender, ...
Wang Yang - - 2013
Methods One hundred and thirty-three patients with essential hypertension were divided into four groups according to criteria proposed by Ganau et al: 36 patients in normal pattern group (I), 34 patients in concentric remodelling pattern group (II), 33 patients in concentric hypertrophy pattern group (III), and 30 patients in eccentric ...
Zhang Mei-qi MQ Department of Emergency Intensive Care Unit, Zhejiang Provincial People's Hospital, Hangzhou 310014, - - 2013
To investigate the mechanisms underlying the protective effects of sodium tanshinone IIA sulfonate (STS) in an ischemia-reperfusion (I/R)-induced rat myocardial injury model. Male SD rats were iv injected with STS, STS+LY294002 or saline (NS) for 15 d. Then the hearts were subjected to 30 min of global ischemia followed by ...
Saeed Maythem - - 2013
To use multi-detector computed tomography (MDCT) for assessing the effects of coronary microemboli on pre-existing acute myocardial infarct (AMI) and to compare this pathology to LAD microembolization and occlusion/reperfusion. An angioplasty balloon catheter was placed in the LAD coronary artery of pigs under X-ray guidance. Four animals served as controls ...
Hahn Joo-Yong JY Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea (J.-Y. Hahn; Y.B.S., E.K.K., S.-H.C., J.-H.C., H.-C.G.); Sejong General Hospital, Bucheon, Korea (C.W.Y.); Chungbuk National University Hospital, Cheongju, Korea (J.-W.B.); Seoul National University, Boramae Medical Center, Seoul, Korea (W.-Y.C.); Konyang University Hospital, Daejon, Korea (J.-H.B.); KEPCO Medical Center, Seoul, Korea (K.J.A.); Yeungnam University Hospital, Daegu, Korea (J.-S.P.); Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea (J.H.O.); Chung-Ang University Hospital, Seoul, Korea (S.-W.K.); Gyeongsang National University Hospital, Jinju, Korea (J.-Y. Hwang); Daegu Catholic University Medical Center, Daegu, Korea (J.K.R.); Kyungpook National University Hospital, Daegu, Korea (H.S.P.); and Korea University Anam Hospital, Seoul, Korea - - 2013
Ischemic postconditioning has been reported to reduce infarct size in patients with ST-segment-elevation myocardial infarction. However, cardioprotective effects of postconditioning have not been demonstrated in a large-scale trial. We performed a multicenter, prospective, randomized, open-label, blinded end-point trial. A total of 700 patients undergoing primary percutaneous coronary intervention (PCI) for ...
Spacek Miloslav - - 2013
Alcohol septal ablation has become a common method to relieve left ventricular outflow track gradient in selected patients with hypertrophic obstructive cardiomyopathy. There is only limited knowledge regarding inadvertent remote (nontarget) myocardial necrosis caused by septal collateral recruitment. Herein we describe a case of unexpected contrast medium leakage through newly ...
Sonmez Osman - - 2013
Little is known about whether estimated glomerular filtration rates (eGFR) affect left ventricular (LV) function and gain benefit with antiremodeling treatment in patients with ST-elevation myocardial infarction (STEMI). We investigated the effect of eGFR on LV function using tissue Doppler imaging (TDI) parameters. In addition, we sought to evaluate the ...
Jang Sung-Won - - 2013
Left anterior line (LAL) has been used as a substitute for mitral isthmus line for catheter ablation of chronic atrial fibrillation (AF). However, it results in left anterolateral conduction delay and might affect left atrial (LA) contractility. We aimed to investigate whether LAL decreases LA appendage function. This study included ...
Romppanen Hannu - - 2013
Background. The BASE-ACS trial demonstrated an outcome of the titanium-nitride-oxide-coated bioactive stents (BAS) statistically non-inferior to that of the everolimus-eluting stents (EES) at 12-month follow-up in patients presenting with acute coronary syndrome (ACS). We performed a post hoc analysis of the BASE-ACS trial with particular focus on stent-oriented versus patient-oriented ...
Satoh Shinji - - 2013
We evaluated a hypothesis that thrombus aspiration with distal protection is superior to simple thrombus aspiration in patients treated with primary percutaneous coronary intervention (PCI). A total of 176 consecutive patients with ST-segment elevation myocardial infarction were enrolled in this study and assigned to either the thrombus aspiration group (A, ...
Vrtovec Bojan - - 2013
In an open-label blinded study, we compared intracoronary and transendocardial CD34(+) cell transplantation in patients with nonischemic dilated cardiomyopathy. Of the 40 patients with dilated cardiomyopathy, 20 were randomized to receive intracoronary injection and 20 received transendocardial CD34(+) cell delivery. In both groups, CD34(+) cells were mobilized by filgrastim, collected ...
Balli Sevket - - 2013
We sought to investigate whether echocardiography with tissue Doppler imaging identifies myocardial dysfunction in children with benign joint hypermobility syndrome (BJHS). This cross-sectional study enrolled 75 children with BJHS and 70 healthy children. We performed detailed echocardiography in individuals with BJHS without inherited connective tissue disorders. Any congenital or acquired ...
Panizo Sara - - 2013
Left ventricular hypertrophy (LVH), a common complication in chronic kidney disease (CKD), is associated with high cardiovascular mortality. The aim of this experimental study was to analyze the effect of different vitamin D receptor activators (VDRAs) on both LVH and myocardial fibrosis in chronic renal failure (CRF). Male Wistar rats ...
Hamdani Nazha - - 2013
-Obesity and diabetes are important metabolic risk factors and frequent comorbidities in heart failure with preserved ejection fraction (HFPEF). They contribute to myocardial diastolic dysfunction (DD) through collagen deposition or titin modification. The relative importance for myocardial DD of collagen deposition and titin modification was investigated in obese, diabetic ZSF1 ...
Song B - - 2013
In this study, electrical and structural remodeling of ventricles was examined in tachycardia-induced heart failure (HF). We studied two groups of weight-matched adult male mongrel dogs: a sham-operated control group (n=5) and a pacing group (n=5) that underwent ventricular pacing at 230 bpm for 3 weeks. Clinical symptoms of congestive ...
Lee Cheol Whan - - 2013
A comprehensive evaluation of culprit coronary lesions may help to understand vulnerable plaques responsible for ST-segment elevation myocardial infarction (STEMI). We compared intravascular ultrasound (IVUS) and histological findings in culprit coronary plaques from 94 patients with STEMI (n = 54) or stable angina (n = 40). Tissue specimens were obtained by directional coronary atherectomy ...
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