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Results 151 - 200 of 2033
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Conti Alberto A aAtrial Fibrillation Outpatient Clinic and Emergency Medicine bEmergency Medicine, Department of Critical Care Medicine and Surgery, cDysrhytmias Unit, Department of Cardiology, University of Florence, Careggi University Hospital, Florence, - - 2014
Patients with recent-onset atrial fibrillation (AF) and cardiac troponin I (cTnI) elevations show poor outcomes. Coronary heart disease might be a cause, consequence, or an innocent bystander. The aim of this study was to recognize and treat coronary heart disease to avoid adverse events. Patients with recent-onset AF participated in ...
Liu Yan-Li YL Department of Laboratory Medicine, Lianyungang Hospital Affiliated Bengbu Medical College, Lianyungang, Jiangsu 222006, P.R. - - 2014
When introduced into the infarcted heart, bone marrow‑derived mesenchymal stem cells (MSCs) prevent the heart from deleterious remodeling and improve its recovery. The aim of the present study was to investigate the effects of Ginkgo biloba extract (EGb) 761 on the infarcted myocardium microenvironment following MSC transplantation. The established rat ...
Fukunaga Masashi M From the Cardiovascular Division (M.F., K.F., D.K., H.S., K.M., H.T., T. Imanaka, T. Iwasaku, T.N., M.S., H.A., T.M.), Division of Coronary Heart Disease (M.M., M.O.), and Department of Radiology (K.K.), Hyogo College of Medicine, Nishinomiya, - - 2014
Despite a sufficient coronary blood flow after primary percutaneous coronary intervention for patients with ST-segment-elevation myocardial infarction; some patients have a poor outcome because of microcirculatory damage. This study evaluates whether the thermodilution-derived coronary blood flow parameters immediately after primary percutaneous coronary intervention predict early microvascular damage and midterm outcomes ...
Kwon Jin-Sook JS Research Laboratory of Cardiovascular Regeneration, Chonnam National University Hospital, Gwangju, - - 2014
We elucidated the therapeutic potential of human umbilical vein endothelial cells (HUVECs) for ameliorating progressive heart failure in a myocardial infarction (MI) rat model. MI was induced by ligation of left anterior descending artery, and HUVEC was transplanted 1week after MI. Cardiac function was evaluated by echocardiography, and histological analyses ...
Wardak Khalil S KS Broward County Medical Examiner and Trauma Services, 5301 S.W. 31st Avenue, Fort Lauderdale, FL, 33312, - - 2014
Drowning is a diagnosis of exclusion based on circumstantial and autopsy correlation. Sugimura proposed a threshold value of 14.1 for the Drowning Index (DI), the ratio of lung and pleural fluid to spleen weight, as a surrogate marker to diagnose drowning. We questioned the use of DI in diagnosing drowning. ...
Reddy Yeruva Madhu YM Division of Cardiovascular Diseases, Cardiovascular Research Institute, University of Kansas Hospital and Medical Center, Kansas City, - - 2014
Data on relative safety, efficacy, and role of different percutaneous left ventricular assist devices for hemodynamic support during the ventricular tachycardia (VT) ablation procedure are limited. We performed a multicenter, observational study from a prospective registry including all consecutive patients (N=66) undergoing VT ablation with a percutaneous left ventricular assist ...
Chou Chu-Lin CL Institute of Medical Sciences, Tzu Chi University, Hualien, - - 2014
The outcomes of Chinese patients undergoing dialysis after coronary revascularization are unknown. We examined the outcomes of Taiwanese dialysis patients after coronary artery bypass grafting (CABG), percutaneous transluminal coronary angioplasty (PTCA), or coronary stenting. Using data from the National Health Institutes Research Database, we determined the outcomes of 1,287 dialysis ...
Türkmen Muhsin M aDepartment of Cardiology, Faculty of Medicine, Medipol University bDepartment of Cardiology, Kartal Kosuyolu Yuksek İhtisas Education and Research Hospital, Istanbul, - - 2014
The exact pathophysiology of slow coronary flow (SCF) phenomenon, characterized by delayed opacification of coronary arteries during coronary angiography, is still unknown, although endothelial dysfunction, inflammation, vasomotor disorders and atherosclerosis are shown. The present study was conducted to investigate whether there is a coagulation pathway abnormality in patients with SCF ...
Ma Jianying - - 2014
The objective of this study was to evaluate changes in left ventricular ejection fraction (LVEF) and left ventricular remodeling after coronary microembolization (CME) and to investigate the protective effects of methylprednisolone (MTP). CME was induced by injection of microspheres (42 mum Dynospheres) into left anterior descending artery of mini swine. ...
Nasseri Boris A BA Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, - - 2014
Intra-myocardial transplantation of CD133(+) bone marrow stem cells (BMC) yielded promising results in clinical pilot trials. We now performed the double-blinded, randomized, placebo-controlled CARDIO133 trial to determine its impact on left ventricular (LV) function and clinical symptoms. Sixty patients with chronic ischaemic heart disease and impaired LV function (left ventricular ...
Gokhroo R K RK Postgraduate Department of Cardiology, JLN Medical College & Associated Group of Hospitals, Ajmer 305 001, Rajasthan (India). - - 2014
Coronary sinus (CS) anatomy is a major predictor of successful implantation of left ventricular (LV) lead and procedural outcome. We therefore made an attempt to look at the CS anatomy and possible feasibility to classify them into categories depending upon their size, branching pattern, location of posterolateral vein (PLV), and ...
Lafci Gokhan G Departments of Cardiovascular Surgery (Drs. Kerim Cagli, Cicek, Diken, Gunertem, Lafci, and Yalcinkaya) and Cardiology (Drs. Kumral Cagli and Turak), Turkiye Yuksek Ihtisas Hospital, 06100 Ankara; Department of Cardiovascular Surgery (Dr. Korkmaz), Ankara Numune Education and Research Hospital, 06330 Ankara; and Department of Cardiovascular Surgery (Dr. Uzun), Ankara Education and Research Hospital, 06340 Ankara; - - 2014
Subvalvular apparatus preservation is an important concept in mitral valve replacement (MVR) surgery that is performed to remedy mitral regurgitation. In this study, we sought to determine the effects of papillary muscle repositioning (PMR) on clinical outcomes and echocardiographic left ventricular function in rheumatic mitral stenosis patients who had normal ...
Kishihara Jun J Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, - - 2014
We evaluated the effect of carvedilol, a beta-blocker with anti-oxidative action, against the atrial fibrillation (AF) inducibility, the development of atrial remodeling and the oxidative stress markers in a canine AF model. AF model was produced by performing 6-week rapid atrial stimulation in 15 dogs. The animals were divided into ...
Amuchastegui Tomas - - 2014
Disulfiram treatment for alcohol dependence is used with acceptable outcomes. By inhibiting the aldehyde dehydrogenase enzyme, this treatment increases acetaldehyde concentration after the ingestion of alcohol causing an unpleasant disulfiram-alcohol reaction. Typical symptoms include flushing, headache, nausea, vomiting, sweating, vertigo, and lightheadedness. However, there have also been descriptions of more ...
Neves Laura M T LM Cardiovascular Physical Therapy Laboratory, Nucleus of Research in Physical Exercise, Universidade Federal de Sao Carlos, Sao Carlos, SP, - - 2014
Background: Reduced respiratory muscle endurance (RME) contributes to increased dyspnea upon exertion in patients with cardiovascular disease. Objective: The objective was to characterize ventilatory and metabolic responses during RME tests in post-myocardial infarction patients without respiratory muscle weakness. Method: Twenty-nine subjects were allocated into three groups: recent myocardial infarction group ...
Miyata Makiko M Department of Cardiology and Hematology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, - - 2014
Sleep-disordered breathing (SDB) has a critical association with mortality and morbidity of patients with chronic heart failure (CHF). Troponin T is a marker of ongoing myocardial damage and predicts adverse clinical outcomes in patients with CHF. Carnitine plays an important role in the utilization of fatty acids in the myocardium. ...
Liu Ping P Department of Neurology, Xuanwu Hospital affiliated to Capital Medical University, Beijing, 100053, - - 2014
To discuss the correlation of tongue manifestation with the site of cerebral infarction in patients with acute cerebral infarction. From March 2008 to February 2009, 200 cases of hospitalized patients with first unilateral cerebral infarction were chosen in the Department of Neurology, Xuanwu Hospital. The correlation of different tongue color, ...
Ashida Terunao T Division of Cardiovascular Disease, The Institute for Adult Diseases Asahi Life - - 2014
We have recently demonstrated that basal cardiomyopathy develops in rabbits with ventricular tachyarrhythmias that have been induced by electrical stimulation of the cervical vagus. This study investigated whether similar basal cardiomyopathy would develop in rabbits with ventricular tachyarrhythmias induced by a single injection of adrenaline. Adrenaline was intravenously infused for ...
Yoshino Satoshi S Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and College of - - 2014
Background: Myocardial bridging (MB) results in compression of the coronary artery lumen in systole, extending into diastole with resultant hemodynamic alternation as reflected by fractional flow reserve (FFR). MB has also been associated with coronary endothelial dysfunction. The objective of this study was to investigate relationship between FFR with dobutamine challenge ...
Zhao X J XJ Department of Cardiology, Affiliated Hospital of Binzhou Medical University, Binzhou, - - 2014
The mechanisms of statins relieving the no-reflow phenomenon and the effects of single-dose statins on it are not well known. This study sought to investigate the effects of inflammation on the no-reflow phenomenon in a rabbit model of acute myocardial infarction and reperfusion (AMI/R) and to evaluate the effects of ...
Tanaka Akihito A Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan, - - 2014
Clopidogrel loading is a standard method to achieve rapid platelet inhibition and prevent thrombotic events. At the current time, little information is available to determine the effect of adjunctive cilostazol compared with clopidogrel loading. We retrospectively analyzed 212 patients undergoing primary percutaneous coronary intervention with drug-eluting stents for ST-segment elevation ...
Bajwa Hisham Z HZ Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, - - 2014
To provide direct evidence that mechanical obstruction of microvessels inhibits infarct resorption (healing) and enhances left ventricular (LV) remodeling using MRI. Animals (n = 20 pigs) served as controls (group I) or were subjected to either 90 min left anterior descending (LAD) coronary artery occlusion/reperfusion (group II) or 90 min ...
Woo Seong-Ill SI Department of Cardiology, Inha University Hospital, Incheon, South - - 2014
Aims: We aimed to investigate whether thrombus aspiration could preserve the index of microcirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). Methods and results: Sixty-three patients with STEMI were randomised into two groups: primary PCI after thrombus aspiration (aspiration group, n=33) and ...
Demir Tuncer T Department of Medical Physiology, Faculty of Medicine, University of Gaziantep, 27310, Gaziantep, - - 2014
In the present study, the expression levels of TRPM1, TRPM2, TRPM3, TRPM4, TRPM5, TRPM6, TRPM7, and TRPM8 genes were evaluated in heart tissues after ischemia/reperfusion (IR). For this study, 30 albino male Wistar rats were equally divided into three groups as follows: Group 1: control group (n:10), Group II: ischemia ...
Yamakawa Kentaro K Department of Anesthesiology, David Geffen School of Medicine, University of California, Los Angeles, - - 2014
The current commonly used cardiac ischemic preconditioning (IPC) protocol, involving three 5-min cycles of ischemia-reperfusion (I/R), may not be clinically beneficial because of its acutely deleterious effects on hemodynamics. This study attempted to assess the effects of a novel stepwise IPC scheme on cardiac function, infarct size, and arrhythmogenesis in ...
Gerbaud Edouard E Soins intensifs cardiologiques - plateau de cardiologie interventionnelle, hôpital Haut-Lévêque, Pessac, France; Institut de rythmologie et de modélisation cardiaque LIRYC, CHU/université de Bordeaux/Inserm U1045, Pessac, France. Electronic address: - - 2014
Heart rate is a major determinant of myocardial oxygen demand; in ST-segment elevation myocardial infarction (STEMI), patients treated with primary percutaneous intervention (PPCI), heart rate at discharge correlates with mortality. Ivabradine is a pure heart rate-reducing agent that has no effect on blood pressure and contractility, and can reverse left ...
Prunier Fabrice F Service de Cardiologie, EA 3860, Laboratoire Cardioprotection, Remodelage et Thrombose, Université Angers, CHU Angers, rue Haute de Reculée, 49045, Angers, France, - - 2014
Local ischemic postconditioning (IPost) and remote ischemic perconditioning (RIPer) are promising cardioprotective therapies in ST-elevation myocardial infarction (STEMI). We aimed: (1) to investigate whether RIPer initiated at the catheterization laboratory would reduce infarct size, as measured using serum creatine kinase-MB isoenzyme (CK-MB) release as a surrogate marker; (2) to assess ...
Değirmencioğlu Aleks A Acibadem University, School of Medicine, Department of Cardiology. - - 2014
Although moderate to severe diastolic dysfunction seems to be associated with poor prognosis after isolated coronary bypass surgery, the impact of mild diastolic dysfunction is not investigated extensively in this group of patients. We evaluated the prognostic implication of mild left ventricular diastolic dysfunction on outcome after isolated coronary bypass ...
Chen Jinling J Department of Echocardiography, Renmin Hospital, Wuhan University, Wuhan, Hubei Province, China. Electronic address: - - 2014
A number of studies have shown that the transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) into the thinned infarct wall improves regional wall motion. In this study, we hypothesized that the injection of biomaterials and MSCs into the infarcted myocardium can preserve left ventricular (LV) function. To test this ...
Pan Kuo-Li KL Division of Cardiology, Chang Gung Memorial Hospital, Chiayi, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Division of Allergy and Immunology and Rheumatology, Division of Nephrology, Chang Gung Memorial Hospital, Chiayi and Division of Cardiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, - - 2014
Objective. The aim of the present study was to investigate the effect of gout on left ventricular (LV) diastolic function and left atrial volume (LAV).Methods. A total of 173 patients were divided into four groups: control (n = 35), asymptomatic hyperuricaemia (n = 30), gouty arthritis without tophi (n = ...
Buchholz Bruno B aInstitute of Cardiovascular Physiopathology, Department of Pathology, School of Medicine, University of Buenos Aires, Argentina. JE Uriburu 950 - 2nd floor. (1114), Buenos Aires - Argentina. bInstitute of Chemistry and Biological Physical Chemistry, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina. Junín 954 - 2nd floor. (1113). Buenos Aires - - - 2014
The α1-adrenergic receptors (α1-ARs) are involved in preconditioning. Given that certain intracellular pathways appear to be shared by preconditioning and postconditioning, it is possible that postconditioning could be also mediated by α1-ARs. The objective was to evaluate, by analyzing infarct size, if α1-ARs activation could trigger postconditioning; and also determine ...
Güngör Barış B Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, 34087, Istanbul, - - 2014
Background: The effectiveness of primary percutaneous coronary intervention (PCI) in ST segment elevation myocardial infarction (STEMI) is well established. The clinical variables associated with poor prognosis in patients with STEMI have been extensively investigated. Right coronary artery (RCA) has two anatomical variations detected on coronary angiography namely C-shaped and sigma ...
Agarwal Rajiv R Department of Medicine, Indiana University School of Medicine and Richard L. Roudebush Veterans Administration Medical Center, Indianapolis, IN, - - 2014
The purpose of this study was to determine among maintenance hemodialysis patients with echocardiographic left ventricular hypertrophy and hypertension whether in comparison with a β-blocker-based antihypertensive therapy, an angiotensin converting enzyme-inhibitor-based antihypertensive therapy causes a greater regression of left ventricular hypertrophy. Subjects were randomly assigned to either open-label lisinopril (n ...
Gonçalves Susana S Departamento de Cardiologia, Instituto Cardiovascular de Lisboa, Lisboa, Portugal; Serviço de Cardiologia, Centro Académico de Medicina de Lisboa, Hospital de Santa Maria, CCUL, Lisboa, Portugal. Electronic address: - - 2014
Introduction The spectrum of hypertensive heart disease is wide, and can include left ventricular dysfunction. The development of echocardiographic parameters to improve patient stratification and to identify early adverse changes could be clinically useful. Aim To identify subclinical left ventricular dysfunction in hypertensive subjects with preserved ejection fraction (>55%), identified ...
Fujii Toshiharu T Division of Cardiology, Tokai University School of Medicine, Isehara, - - 2014
Reducing total ischemic time is important in achieving better outcome in ST-segment elevation myocardial infarction (STEMI). Although the onset-to-door (OTD) time accounts for a large portion of the total ischemic time, factors affecting prolongation of the OTD time are not established. The purpose of this study was to determine the ...
Andreini Daniele D Centro Cardiologico Monzino, IRCCS, Via C. Parea 4, 20138 Milan, Italy; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy. Electronic address: - - 2014
Reliability of coronary angiography by multidetector row CT (MDCT-CA) for stent evaluation is still a matter for debate, and it is unknown whether contrast medium characteristics may affect diagnostic performance of MDCT-CA. We compared iomeprol-400 with iodixanol-320 to evaluate coronary stents with MDCT-CA. We randomly assigned 254 patients undergoing coronary ...
Mroziński Paweł - - 2014
Several studies have highlighted that volatile anaesthetics improve myocardial protection in cardiopulmonary bypass coronary surgery. However, the haemodynamic effect of desflurane in off-pump coronary surgery has not been clarified yet. Our study hypothesis was that desflurane-fentanyl anaesthesia could decrease myocardial injury markers and improve haemodynamics compared to propofol-fentanyl in patients ...
Pan Qiao Q 1. Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, - - 2014
Extracellular superoxide dismutase (ecSOD) is a unique scavenger of superoxide anions and a promising target of gene therapy for ischemia/reperfusion injury (I/R). However, conventional gene therapies have limitation in effectiveness and efficiency. This study aimed to investigate the protective effects of ecSOD gene modified bone marrow mesenchymal stromal cells (BMSCs) ...
Ding Wenxiao W Department of Respirology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, - - 2014
Obstructive sleep apnea syndrome (OSAS) is associated with many cardiovascular disorders such as heart failure, hypertension, atherosclerosis, and arrhythmia and so on. Of the many associated factors, chronic intermittent hypoxia (CIH) in particular is the primary player in OSAS. To assess the effects of CIH on cardiac function secondary to ...
Salarifar Mojtaba M Department of Cardiology, Tehran University of Medical Sciences, Tehran Heart Center Hospital, Tehran, IR - - 2014
Before primary percutaneous coronary intervention (PCI) in patients with ST elevation myocardial infarction (STEMI), it is not clear whether a routine early administration of glycoprotein IIb/IIIa inhibitors in the emergency ward is beneficial or their administration in selected cases in the catheterization laboratory. The present randomized clinical trial sought to ...
Helseth Ragnhild R 0000-0001-5012-9214 Department of Cardiology, Oslo University Hospital Ullevål, P.O. Box 4956, Nydalen, 0424 Oslo, Norway ; Faculty of Medicine, University of Oslo, P.O. Box 1078, Blindern, 0316 Oslo, - - 2014
Background. High levels of Pentraxin 3 (PTX3) are reported in acute myocardial infarction (AMI). Aim. To investigate circulating levels and gene expression of PTX3 in patients with AMI and stable angina pectoris (AP) undergoing PCI. Methods. Ten patients with AP and 20 patients with AMI were included. Blood samples were ...
Liu Daliang D 0000-0002-3496-2174 Department of Radiology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Xicheng District, Beijing 100050, - - 2014
Objectives. To analyze the predictive value of coronary computed tomography angiography on acute coronary artery events in patients with type 2 diabetes. Methods. Coronary computed tomography angiography was performed in 250 type 2 diabetic patients. After a follow-up for 5 years, 145 patients were excluded as they did not have ...
Hu Hesheng H School of Medicine, Shandong University, Jinan, China; Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, - - 2014
Nerve growth factor (NGF) is involved in nerve sprouting, hyper-innervation, angiogenesis, anti-apoptosis, and preservation of cardiac function after myocardial infarction (MI). Positively modulating NGF expression may represent a novel pharmacological strategy to improve post-infarction prognosis. In this study, lentivirus encoding NGF short interfering RNA (siRNA) was prepared, and MI was ...
Temiz Ahmet A Department of Cardiology, Çanakkale Onsekiz Mart University, Çanakkale, - - 2014
Background Platelet-to-lymphocyte ratio (PLR) is a new prognostic marker in coronary artery disease. We aimed to evaluate the relationship between PLR and in-hospital mortality in patients with ST-elevated acute myocardial infarction (AMI). Material and Methods The present study included 636 patients with ST-elevated AMI. The study population was divided into ...
Ran K K Department of Anesthesiology, The Second Xiangya Hospital, Central South University, - - 2014
We examined the protective effects of Ginkgo biloba extract (EGb761) postconditioning on myocardial ischemia reperfusion injury in rabbits. Four groups of 8 white rabbits were allocated to: pseudo surgery group: the left coronary was lined without blocking for 160 min after thoracotomy; ischemia and reperfusion group (IR): the left anterior ...
Yamamoto Yasumasa Y Department of Neurology, Kyoto Second Red Cross - - 2014
Small deep brain infarcts are often caused by two different vascular pathologies: 1. atheromatous occlusion at the orifice of large caliber penetrating arteries termed branch atheromatous disease (BAD) and 2. lipohyallinotic degenerative changes within the course of penetrating arteries termed lipohyalinitic degeneration. Representative vascular territories of BAD type infarcts are ...
Akturk Ibrahim Faruk IF Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Halkali, Istanbul, - - 2014
Insulin-like growth factor-1 (IGF-1) has atheroprotective effects via reduction in oxidative stress, cellular apoptosis, pro-inflammatory signaling, and endothelial dysfunction. We hypothesized that low levels of IGF-1 may be associated with the severity and extent of coronary artery disease and development of the coronary no-reflow phenomenon in patients with acute ST-elevation ...
Hu Jialu J Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, - - 2014
Although renal denervation (RD) has been shown to be effective in treating post- myocardial Infarction (MI) heart failure (HF) in animal models and clinical trials, its utility as a standalone treatment without traditional drug treatment for post-MI HF still needs to be investigated. Rats were randomly assigned into seven experimental ...
Chakraborty P K PK Dr Pijush Kumar Chakraborty, Associate Professor, Department of Biochemistry, Mymensingh Medical College, Mymensingh, - - 2014
This case control cross sectional study was carried out in the Department of Biochemistry, Mymensingh Medical College in collaboration with Cardiology Department of Mymensingh Medical College Hospital, Mymensingh during the period of July 2004 to June 2005. The aim of the study was to explore the status of serum magnesium ...
Guo Tong-Shuai TS Department of Cardiovascular Medicine, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, No. 277 Yanta West Road, Xi'an 710061, China. - - 2014
Salt-sensitive individuals show earlier and more serious cardiac damage than nonsalt-sensitive ones. Some studies have suggested that microRNA-133a could reduce cardiac hypertrophy and myocardial fibrosis. The current study aims to investigate the different functions of high-salt intake on salt-sensitive (SS) rats and Sprague-Dawley (SD) rats and the involvement of microRNA-133a ...
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