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Results 101 - 150 of 2035
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Zhi-Bin Huang H Department of Cardiology, The First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou, - - 2014
The objective was to investigate the effects of valsartan on the electrophysiological characteristics of left ventricular hypertrophic myocardium in spontaneously hypertensive rats (SHR). A total of 24 10-week-old male SHR were divided into two groups: valsartan and non-valsartan groups (n=12 in each). Twelve 10-week-old Wistar-Kyoto rats were served as the ...
Garatti Andrea A Department of Cardiac Surgery, I.R.C.C.S. Policlinico San Donato, Milan, - - 2014
The aim was to assess the impact of right ventricular dysfunction (RVD) on the outcome of heart failure (HF) patients undergoing surgical ventricular reconstruction (SVR). A total of 324 patients (65 ± 9 years) with previous myocardial infarction had an echocardiographic assessment of right ventricular (RV) function before and after ...
Salminen Pirjo-Riitta PR Section of Cardiothoracic Surgery, Department of Heart Disease, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Bergen, - - 2014
In an open-chest porcine model, we examined whether myocardial pharmacological conditioning at the time of reperfusion with low-dose insulin or insulin-like growth factor 2 (IGF2), not affecting serum glucose levels, could reduce infarct size and improve functional recovery. Two groups of anaesthetized pigs with either 60 or 40 min. of ...
Yang Rui-Feng RF Department of Cardiology, The 2nd Affiliated Hospital with Kunming Medical University, Kunming, 650101, - - 2014
The objective of this study was to investigate the characteristics of coronary lesions in patients with coronary heart disease complicated with hypertriglyceridemic waist phenotype and determine the relation to risk factors. For this purpose, 105 patients with ≥50 % stenosis in one branch of coronary arteries as confirmed by coronary angiography ...
Jia Zhi Z TEDA International Cardiovascular Hospital, Cardiovascular Clinical College of Tianjin Medical University, TEDA, Tianjin, - - 2014
Objectives: To evaluate the efficacy of a short-term intravenous infusion of levosimendan in patients with heart failure due to acute myocardial infarction (AMI). Methods: This was a randomized, single-center, single-blind study that included 160 patients. Patients were randomly divided into 2 groups: 1 received levosimendan (n = 80) and the ...
Ko Young-Guk YG Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, - - 2014
The purpose of the study was to investigate whether early high-dose potent statin therapy in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention can reduce infarct size compared with conventional low-dose statin therapy. In a randomized placebo-controlled multicenter trial, 185 patients were assigned either to an early ...
Lexis Chris P H CP University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the - - 2014
Metformin treatment is associated with improved outcome after myocardial infarction in patients with diabetes. In animal experimental studies metformin preserves left ventricular function. To evaluate the effect of metformin treatment on preservation of left ventricular function in patients without diabetes presenting with ST-segment elevation myocardial infarction (STEMI). Double-blind, placebo-controlled study ...
Topcu Selim S 1Department of Cardiology, Medical School, Ataturk University, Erzurum, - - 2014
Aim:We aimed to investigate the 6-month efficacy and safety of postprocedural 12-hour tirofiban administration versus 24-hour tirofiban administration in patients with ST-segment elevated myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI).Methods:This retrospective study enrolled 349 patients with STEMI who underwent primary PCI. Following the administration of bolus tirofiban ...
Bang Casper N CN From the Department of Medicine, Weill Cornell Medical College, New York, NY (C.N.B., G.d.S., K.W., R.B.D.); Department of Cardiology, The Heart Center, Rigshospitalet, Copenhagen, Denmark (C.N.B., L.K.); Department of Clinical Science, University of Bergen, Bergen, Norway (E.G.); Department of Medicine, Division of Cardiology, University of Massachusetts Medical School, Worcester (G.P.A.); Department of Medicine, Institution of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden (K.B.); Department of Translational Medical Sciences, Federico II University, Naples, Italy (G.d.S.); Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden (B.D.); and Department of Cardiology, Copenhagen University Hospital Glostrup, Glostrup, Denmark (K.W.). - - 2014
Left ventricular hypertrophy (LVH; high LV mass [LVM]) is traditionally classified as concentric or eccentric based on LV relative wall thickness. We evaluated the prediction of subsequent adverse events in a new 4-group LVH classification based on LV dilatation (high LV end-diastolic volume [EDV] index) and concentricity (mass/end-diastolic volume [M/EDV](2/3)) ...
Saini Shiv Sajan SS 1Neonatal Unit, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India. 2Department of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, - - 2014
We evaluated hemodynamic changes in preterm neonates with septic shock using functional echocardiography and studied the effects of vasoactive drugs on hemodynamic variables. Prospective observational study. Level III neonatal ICU. We enrolled 52 preterm neonates with septic shock (shock group) and an equal number of gestation and postnatal age-matched healthy ...
Ho Yuan-Chih YC 1Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. 2Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. 3Institute of Shock Wave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, - - 2014
We tested the hypothesis that, as compared with conventional door-to-balloon, shortened door-to-balloon time would further improve 30-day outcome in ST-elevation myocardial infarction (STEMI) patients undergoing primary stenting. Retrospective cohort study SETTING:: Academic tertiary care hospital with approximately 2600 beds PATIENTS:: Between January 2008 and December 2009, 266 ST-elevation myocardial infarction ...
Chen Xiang-Qi XQ Fujian Institute of Coronary Artery Disease and Department of Cardiology, Union Hospital, Fujian Medical University, Fuzhou, Fujian 350001, - - 2014
The aim of this study was to investigate whether the modification of bone marrow-derived mesenchymal stem cells (BMSCs) with the fused FGF4 (fibroblast growth factor 4)-bFGF (basic fibroblast growth factor) gene could improve the expression and secretion of BFGF, and increase the efficacies in repairing infarcted myocardium. We used in-Fusion ...
Asaad Nidal N Department of Cardiology, Heart Hospital, Hamad Medical Corporation , - - 2014
Objectives: To assess the impact of on-admission heart rate (HR) in patients presenting with acute coronary syndrome (ACS). Methods: Data were collected retrospectively from the second Gulf Registry of Acute Coronary Events. Patients were divided according to their initial HR into: (I: < 60, II: 60-69, III: 70-79, IV: 80-89 ...
Shehata M M Department of Cardiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt - - - 2014
Myocardial injury commonly occurs during percutaneous coronary intervention (PCI). Several agents that mimic ischemic preconditioning could help minimize this phenomenon. This study evaluated the cardioprotective role of intracoronary Adenosine in elective PCI. 100 diabetic patients with chronic stable angina were prospectively enrolled, then randomly assigned to undergo PCI with intracoronary ...
Xue Ling L Department of Cardiovascular Medicine, Qilu Hospital, Shandong University, No 107 Wenhua Xi Road, Jinan 250012, P.R. China; Department of Cardiovascular Medicine, Third Affiliated Hospital of Liaoning Medical College, Jinzhou 121000, Liaoning Province, - - 2014
To investigate the effect of salvianolic acid B on rats with myocardial ischemia-reperfusion injury. SD rats were randomly divided into five groups (n=10 in each group): A sham operation group, B ischemic reperfusion group model group, C low dose salvianolic acid B group, D median dose salvianolic acid B group, ...
Hu Qian Q Emergency Department, Fifth Affiliated Hospital of Zhengzhou University, Henan 450003, - - 2014
To explore protective effect of rosiglitazone on myocardial ischemia reperfusion injury. A total of 48 male SD rats were randomly divided into control group (A), I/R group(B), high dose of rosiglitazone (C), low dose of rosiglitazone (D). Plasm concentration of creatine kinase (CK), CK-MB, hsCRP, Superoxide dismutase (SOD), malondialdehyde (MDA), ...
Lavi Shahar S From the Western University (S.L., P.D., A.C., P.G., P.T., G.J., K.S., R.L.), London, Ontario, Canada; and London Health Sciences Centre (S.L., S.D., P.D., A.C., P.G., P.T., G.J., K.S., R.L.), London, Ontario, - - 2014
Remote ischemic preconditioning may result in reduction in infarct size during percutaneous coronary intervention (PCI). It is unclear whether remote ischemic postconditioning (RIPost) will reduce the incidence of myocardial injury after PCI, and whether ischemic conditioning of a larger remote organ (thigh versus arm) would provide further myocardial protection. We ...
Liu Chao C Department of Cardiac Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China, - - 2014
The purpose of this study was to determine the combined effect of transmyocardial laser revascularization (TMLR) and the implantation of endothelial progenitor cells (EPCs) on cardiac function of ischemic hearts in canines. The left anterior descending artery (LAD) was occluded to establish the canine model of acute myocardial infarct (AMI). ...
Ahn Sung Gyun SG Division of Cardiology, Yonsei University Wonju College of Medicine, Wonju, - - 2014
We aimed to investigate whether combination therapy using intracoronary (IC) abciximab and aspiration thrombectomy (AT) enhances myocardial perfusion compared to each treatment alone in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). We enrolled 40 patients with STEMI, who presented within 6 h of symptom onset ...
Ozdemir Ahmet Coskun AC Department of Cardiac and Vascular Surgery (Drs. Baltalarli and Ozdemir), Ozel Denizli Cerrahi Hospital, 20020 Denizli; and Department of Cardiac and Vascular Surgery (Dr. Emrecan), Pamukkale University, 20070 Denizli; - - 2014
In the present study of mitral valve replacement, we investigated whether complete preservation of both leaflets (that is, the subvalvular apparatus) is superior to preservation of the posterior leaflet alone. Seventy patients who underwent mitral valve replacement in our clinic were divided into 2 groups: MVR-B (n=16), in whom both ...
Ramos Cassiana Maria Garcez CM Pontifícia Universidade Católica do Paraná, Curitiba, PR, - - 2014
Most cardiomyocytes do not regenerate after myocardial infarction. Porcine small intestinal submucosa has been shown to be effective in tissue repair. To evaluate myocardial tissue regeneration and functional effects of SIS implantation in pigs after left ventriculotomy. Fifteen pigs were assigned to two groups: porcine small intestinal submucosa (SIS) (N=10) ...
Yetimakman Ayse Filiz AF 1Department of Pediatrics, Istanbul Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, - - 2014
Objectives: Cardiology follow up is important in thalassemia major patients. The object of this study is to define parameters which can be used in the early detection of cardiac impairment. Material and Methods: Forty seven beta thalassemia major patients (mean age 16.3 ± 4.47 years; 22 boys, 25 girls) whose left ...
Peix Amalia A From the Institute of Cardiology, La Habana, - - 2014
The purpose of this study was to evaluate the ability of rest gated SPECT myocardial perfusion imaging (MPI) and intraventricular synchronism, to identify heart failure (HF) patients most likely to experience cardiac events. We studied 165 patients with left ventricular ejection fraction of less than 40%, who were divided in ...
Abe Daisuke D Department of Cardiology, Ibaraki Prefectural Central Hospital, Tomobe, - - 2014
There are a few retrospective subgroup analyses or registries of large-vessel (≥3.5mm) stenting. We investigated clinical outcomes of patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and bare-metal stents (BMS) in large coronary vessels. Of 1100 STEMI patients registered in the Ibaraki ...
Winchester David E DE Malcom Randall VA Medical Center, 1601 SW Archer Rd 111D, Gainesville, FL, 32608, USA, - - 2014
Inappropriate use of myocardial perfusion imaging (MPI) may vary depending on the training, specialty, or practice location of the clinician. We conducted a cross-sectional investigation of consecutive patients who underwent MPI at our Veterans Affairs medical center between December 2010 and July 2011. Characteristics of the MPI ordering clinicians were ...
Ueda Tomoya T First Department of Internal Medicine, Nara Medical University, Nara, - - 2014
Percutaneous coronary intervention (PCI)-related cardiac enzyme elevation is an independent risk factor for adverse clinical outcomes, but preprocedural predictors of this complication have not been established. This study evaluated the morphological characteristics of culprit lesions by frequency-domain optical coherence tomography (FD-OCT), and examined their predictive value for procedure-related myocardial injury ...
Shillcutt Sasha K SK Department of Anesthesiology, University of Nebraska Medical Center, Omaha, - - 2014
Patients with left ventricular diastolic dysfunction (LVDD) are at increased risk of postoperative adverse events. The primary aim of this study was to evaluate the safety and feasibility of using echocardiography-guided hemodynamic management (EGHEM) during surgery in subjects with LVDD compared to conventional management. The feasibility of using echocardiography to ...
Zhou Chenghui C Department of Anesthesiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Xicheng District, Beijing - - 2014
The role of heme oxygenase-1 (HO-1) in the cardioprotection induced by delayed remote ischemic preconditioning (DRIPC) has not been investigated. Therefore, this study was designed to investigate whether HO-1 is involved in DRIPC-mediated cardioprotection in an isolated perfused rat heart model. Isolated rat hearts were subjected to 30 min ischemia followed ...
Wang Tao T Department of Cardiology, The Fourth People's Hospital of Jinan, The Second Affiliated Hospital of Tai Shan Medical College, Jinan, - - 2014
The aim of this study was to test the hypotheses that epicardial adipose tissue (EAT) can be a marker of severe coronary artery disease in patients with acute myocardial infarction. Overall, 373 cases who underwent coronary angiography were classified into 2 groups by SYNTAX score: low-score and high-score group. EAT ...
Kurtul Alparslan A 1Department of Cardiology, Ankara Education and Research Hospital, Ankara, - - 2014
Low serum albumin (SA) levels are associated with increased cardiovascular mortality. We investigated whether baseline SA levels are associated with no-reflow following primary percutaneous coronary intervention (pPCI). A total of 536 patients (aged 60 ± 13 years; 74% men) who underwent pPCI were enrolled. The patients were divided into 2 ...
Zhao Wei - - 2014
The importance of achieving complete revascularization by percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (MI) remains unclear. To compare short-term exercise capacity following acute ST-elevation myocardial infarction (STEMI), in patients receiving PCI with stenting, between those completely revascularized (CR) and those incompletely revascularized (IR). We retrospectively reviewed ...
Liu Shuangmei S Department of Physiology, Medical School of Nanchang University, Nanchang 330006, - - 2014
Myocardial ischemia elicits a sympathoexcitatory response characterized by increase in blood pressure and sympathetic nerve activity. Puerarin, a major active ingredient extracted from the traditional Chinese plant medicine Ge-gen, has been widely used in treatment of myocardial and cerebral ischemia. However, little is known about the mechanism. Our study was ...
Hemayat Sevil S Faculty of Medicine, Islamic Azad University, Tehran, - - 2014
This study aimed at comparing the development of tricuspid and mitral regurgitation between the right ventricular outflow tract (RVOT) and right ventricular apex (RVA) pacing. We prospectively enrolled 164 patients for permanent pacemaker implantation due to sick sinus syndrome or atrioventricular block and randomly divided them into two equal groups ...
Jeong Hae Chang HC Chonnam National University - - 2014
The effects of statins on the prognosis of patients with left ventricular (LV) systolic dysfunction remain controversial. The aim of this study was to assess the effect of statin treatment on clinical outcomes in acute myocardial infarction (AMI) patients with LV systolic dysfunction. A total of 5,119 AMI patients with ...
Miyoshi Hirokazu H Cardiovascular Section, Higashi Tokushima Medical Center, National Hospital - - 2014
Previous studies have examined the negative impacts of individual cardiovascular risk (CVR) factors on left atrial (LA)-left ventricular (LV) interaction, whereas the combined effects of these risk factors are insuffi ciently elucidated. We studied 176 asymptomatic patients with CVR factors and age-matched 50 healthy individuals by conventional and 2-dimensional speckle-tracking ...
Miranda Douglas Pinheiro DP Post Graduation Program in Research and Development - Medical Biotechnology, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil, - - 2014
High intensity systematic physical training leads to myocardial morphophysiological adaptations. The goal of this study was to investigate if differences in training were correlated with differences in cardiac sympathetic activity. 58 males (19-47 years), were divided into three groups: strength group (SG), (20 bodybuilders), endurance group (EG), (20 endurance athletes), and ...
Sun Cheuk-Kwan CK Department of Emergency Medicine, E-DA Hospital, I-Shou University, Kaohsiung, - - 2014
This study tested whether adipose-derived mesenchymal stem cells (ADMSC) embedded in platelet-rich fibrin (PRF) scaffold is superior to direct ADMSC implantation in improving left ventricular (LV) performance and reducing LV remodeling in a rat acute myocardial infarction (AMI) model of left anterior descending coronary artery (LAD) ligation. Twenty-eight male adult ...
Tanındı Aslı A Department of Cardiology, Ufuk University Faculty of Medicine, Ankara, Turkey. - - 2014
Objectives: We investigated the relation between neutrophil to lymphocyte ratio (N/L) and the extent, severity, and complexity of coronary artery disease (CAD) and myocardial perfusion. Study design: One hundred and fifty-one patients who underwent coronary angiography with stable angina pectoris (SAP) (n=93) or acute coronary syndrome (ACS) (n=58) were included ...
Turgeman Yoav Y Heart Institute, H'aEmek Medical Center, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, - - 2014
We assess the epicardial and microcirculation flow characteristics, and clinical outcome by using catheter aspiration after each stage of primary percutaneous coronary intervention (PPCI). Conflicting data are reported regarding early and late benefit of using aspiration catheter in the initial phase PPCI. A total of 100 patients with ST-segment elevation ...
Taskesen T T Cardiology Department, Harborview Medical Center, Seattle, Washington, - - 2014
Studies have shown different effect of intermediate QRS prolongation on major cardiovascular events in acute myocardial infarction (AMI) patients. The aim of this study was to investigate the predictive and prognostic value of intermediate QRS prolongation on in-hospital complication rate and long term mortality in patients with AMI. We performed ...
Tungsubutra Wiwun - - 2014
To investigate the impact of thrombus burden on 1-year clinical outcomes in patients who underwent emergent percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI). Angiographic evidence of intracoronary thrombus adversely affects the outcome of PCI in STEMI. Large thrombus burden (> or = 2 times vessel diameter) ...
Kim Ji Won JW Department of Cardiovascular Medicine, Regional Cardiocerebrovascular Center, Wonkwang University Hospital, Iksan, - - 2014
High dose rosuvastatin loading before percutaneous coronary interventions (PCI) reduces the myocardial damage and the incidence of adverse cardiac events in patients with stable angina and acute coronary syndrome. However, no studies are present yet about rosuvastatin loading in patients with ST-segment elevation myocardial infarction (STEMI) in a primary PCI ...
Bavry Anthony A AA North Florida/South Georgia Veterans Health System, Gainesville, FL; Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL. Electronic address: - - 2014
Endothelial dysfunction is highly prevalent and associated with adverse outcomes among patients without obstructive coronary artery disease (CAD). Angiotensin II inhibition may improve endothelial function, but with continued treatment, "aldosterone escape" may occur. Thus, it is unknown if adding aldosterone blockade further improves endothelial function. In a double-blind, parallel-group, repeated-measures ...
Behrenbeck Thomas R - - 2014
Intramyocardial microvessels show functional changes in early stages of atherosclerosis prior to epicardial coronary artery stenosis. However, clinical CT does not have adequate spatial resolution to resolve the microvessels. To clinically detect changes in the function of the intramyocardial microcirculation, the spatial heterogeneity of the distribution of myocardial perfusion (F) ...
Papai Gyorgy G Hungarian National Ambulance - - 2014
The efficacy of the transtelephonic ECG system (TTECG) in the management of ST segment elevation myocardial infarction (STEMI) was examined with regard to the ambulance service- and percutaneous coronary intervention (PCI)-related delay times, the prehospital medical therapy and the in-hospital mortality rate. The study was conducted as a collaborative effort ...
Oğuz Didem D Department of Cardiology, Faculty of Medicine, Başkent University; İstanbul-Turkey. - - 2014
This study aims to show the effect of myeloperoxidase (MPO), hsCRP, TNF-alpha values and leukocyte count on the development of coronary collateral arteries in patients with severely diseased coronary arteries. Current study is an observational cross-sectional study. In the study, 295 patients who had functional obstruction or total coronary occlusion ...
Assmus Birgit B Cardiology, Deptartment of Medicine III, Goethe University Frankfurt, Theodor-Stern-Kai 7, Frankfurt 60590, - - 2014
In the REPAIR-AMI trial, intracoronary infusion of bone marrow-derived cells (BMCs) was associated with a significantly greater recovery of contractile function in patients with acute myocardial infarction (AMI) at 4-month follow-up than placebo infusion. The current analysis investigates clinical outcome and predictors of event-free survival at 5 years. In the ...
Polizopoulou Zoe S ZS Diagnostic Laboratory, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, - - 2014
Cardiac troponin I (cTnI) is a biomarker correlated with the severity of myocardial injury. It is hypothesized that serial assessment of cTnI could provide information about the disease progression in chronic heart failure. The purpose of the study was to correlate serial serum cTnI concentrations with clinical scoring and select ...
Joffre Jérémie J Medical Intensive Care Unit, Cochin Hospital, Hôpitaux Universitaires Paris Centre, Assistance Publique des Hôpitaux de Paris, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Faculté de médecine, 15 rue de l'Ecole de Médecine, 75006 Paris, France; INSERM U970, Paris Cardiovascular Research Center (PARCC), European Georges Pompidou Hospital, 56 rue Leblanc, 75015 Paris, - - 2014
The leading cause of sudden cardiac death is myocardial ischemia. As for uncomplicated acute myocardial infarction (AMI), international guidelines plead for early coronary angiography with, in case of culprit lesion, angioplasty and stent implantation. However after cardiac arrest (CA), shock, hypothermia and changes in antiplatelet pharmacokinetic may promote stent thrombosis ...
Margonato Alberto A aCardiology and Coronary Intensive Care Unit bBone Metabolic Unit, Division of Cardiovascular Science, IRCCS S. Raffaele Hospital, Milan, - - 2014
To assess serum levels of the plaque calcification regulators osteoprotegerin (OPG) and Matrix Gla-proteins (MGP) in individuals with stable angina and acute myocardial infarction submitted to coronary angiography and their relation to coronary artery disease burden. The study included 40 individuals affected by ST-elevation myocardial infarction (STEMI) and 40 individuals ...
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