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Abe Daisuke D Department of Cardiology, Ibaraki Prefectural Central Hospital, Tomobe, - - 2014
There are a few retrospective subgroup analyses or registries of large-vessel (≥3.5mm) stenting. We investigated clinical outcomes of patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and bare-metal stents (BMS) in large coronary vessels. Of 1100 STEMI patients registered in the Ibaraki ...
Winchester David E DE Malcom Randall VA Medical Center, 1601 SW Archer Rd 111D, Gainesville, FL, 32608, USA, - - 2014
Inappropriate use of myocardial perfusion imaging (MPI) may vary depending on the training, specialty, or practice location of the clinician. We conducted a cross-sectional investigation of consecutive patients who underwent MPI at our Veterans Affairs medical center between December 2010 and July 2011. Characteristics of the MPI ordering clinicians were ...
Ueda Tomoya T First Department of Internal Medicine, Nara Medical University, Nara, - - 2014
Percutaneous coronary intervention (PCI)-related cardiac enzyme elevation is an independent risk factor for adverse clinical outcomes, but preprocedural predictors of this complication have not been established. This study evaluated the morphological characteristics of culprit lesions by frequency-domain optical coherence tomography (FD-OCT), and examined their predictive value for procedure-related myocardial injury ...
Shillcutt Sasha K SK Department of Anesthesiology, University of Nebraska Medical Center, Omaha, - - 2014
Patients with left ventricular diastolic dysfunction (LVDD) are at increased risk of postoperative adverse events. The primary aim of this study was to evaluate the safety and feasibility of using echocardiography-guided hemodynamic management (EGHEM) during surgery in subjects with LVDD compared to conventional management. The feasibility of using echocardiography to ...
Zhou Chenghui C Department of Anesthesiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Xicheng District, Beijing - - 2014
The role of heme oxygenase-1 (HO-1) in the cardioprotection induced by delayed remote ischemic preconditioning (DRIPC) has not been investigated. Therefore, this study was designed to investigate whether HO-1 is involved in DRIPC-mediated cardioprotection in an isolated perfused rat heart model. Isolated rat hearts were subjected to 30 min ischemia followed ...
Wang Tao T Department of Cardiology, The Fourth People's Hospital of Jinan, The Second Affiliated Hospital of Tai Shan Medical College, Jinan, - - 2014
The aim of this study was to test the hypotheses that epicardial adipose tissue (EAT) can be a marker of severe coronary artery disease in patients with acute myocardial infarction. Overall, 373 cases who underwent coronary angiography were classified into 2 groups by SYNTAX score: low-score and high-score group. EAT ...
Kurtul Alparslan A 1Department of Cardiology, Ankara Education and Research Hospital, Ankara, - - 2014
Low serum albumin (SA) levels are associated with increased cardiovascular mortality. We investigated whether baseline SA levels are associated with no-reflow following primary percutaneous coronary intervention (pPCI). A total of 536 patients (aged 60 ± 13 years; 74% men) who underwent pPCI were enrolled. The patients were divided into 2 ...
Zhao Wei - - 2014
The importance of achieving complete revascularization by percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (MI) remains unclear. To compare short-term exercise capacity following acute ST-elevation myocardial infarction (STEMI), in patients receiving PCI with stenting, between those completely revascularized (CR) and those incompletely revascularized (IR). We retrospectively reviewed ...
Liu Shuangmei S Department of Physiology, Medical School of Nanchang University, Nanchang 330006, - - 2014
Myocardial ischemia elicits a sympathoexcitatory response characterized by increase in blood pressure and sympathetic nerve activity. Puerarin, a major active ingredient extracted from the traditional Chinese plant medicine Ge-gen, has been widely used in treatment of myocardial and cerebral ischemia. However, little is known about the mechanism. Our study was ...
Hemayat Sevil S Faculty of Medicine, Islamic Azad University, Tehran, - - 2014
This study aimed at comparing the development of tricuspid and mitral regurgitation between the right ventricular outflow tract (RVOT) and right ventricular apex (RVA) pacing. We prospectively enrolled 164 patients for permanent pacemaker implantation due to sick sinus syndrome or atrioventricular block and randomly divided them into two equal groups ...
Jeong Hae Chang HC Chonnam National University - - 2014
The effects of statins on the prognosis of patients with left ventricular (LV) systolic dysfunction remain controversial. The aim of this study was to assess the effect of statin treatment on clinical outcomes in acute myocardial infarction (AMI) patients with LV systolic dysfunction. A total of 5,119 AMI patients with ...
Miyoshi Hirokazu H Cardiovascular Section, Higashi Tokushima Medical Center, National Hospital - - 2014
Previous studies have examined the negative impacts of individual cardiovascular risk (CVR) factors on left atrial (LA)-left ventricular (LV) interaction, whereas the combined effects of these risk factors are insuffi ciently elucidated. We studied 176 asymptomatic patients with CVR factors and age-matched 50 healthy individuals by conventional and 2-dimensional speckle-tracking ...
Miranda Douglas Pinheiro DP Post Graduation Program in Research and Development - Medical Biotechnology, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil, - - 2014
High intensity systematic physical training leads to myocardial morphophysiological adaptations. The goal of this study was to investigate if differences in training were correlated with differences in cardiac sympathetic activity. 58 males (19-47 years), were divided into three groups: strength group (SG), (20 bodybuilders), endurance group (EG), (20 endurance athletes), and ...
Sun Cheuk-Kwan CK Department of Emergency Medicine, E-DA Hospital, I-Shou University, Kaohsiung, - - 2014
This study tested whether adipose-derived mesenchymal stem cells (ADMSC) embedded in platelet-rich fibrin (PRF) scaffold is superior to direct ADMSC implantation in improving left ventricular (LV) performance and reducing LV remodeling in a rat acute myocardial infarction (AMI) model of left anterior descending coronary artery (LAD) ligation. Twenty-eight male adult ...
Tanındı Aslı A Department of Cardiology, Ufuk University Faculty of Medicine, Ankara, Turkey. - - 2014
Objectives: We investigated the relation between neutrophil to lymphocyte ratio (N/L) and the extent, severity, and complexity of coronary artery disease (CAD) and myocardial perfusion. Study design: One hundred and fifty-one patients who underwent coronary angiography with stable angina pectoris (SAP) (n=93) or acute coronary syndrome (ACS) (n=58) were included ...
Turgeman Yoav Y Heart Institute, H'aEmek Medical Center, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, - - 2014
We assess the epicardial and microcirculation flow characteristics, and clinical outcome by using catheter aspiration after each stage of primary percutaneous coronary intervention (PPCI). Conflicting data are reported regarding early and late benefit of using aspiration catheter in the initial phase PPCI. A total of 100 patients with ST-segment elevation ...
Taskesen T T Cardiology Department, Harborview Medical Center, Seattle, Washington, - - 2014
Studies have shown different effect of intermediate QRS prolongation on major cardiovascular events in acute myocardial infarction (AMI) patients. The aim of this study was to investigate the predictive and prognostic value of intermediate QRS prolongation on in-hospital complication rate and long term mortality in patients with AMI. We performed ...
Tungsubutra Wiwun - - 2014
To investigate the impact of thrombus burden on 1-year clinical outcomes in patients who underwent emergent percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI). Angiographic evidence of intracoronary thrombus adversely affects the outcome of PCI in STEMI. Large thrombus burden (> or = 2 times vessel diameter) ...
Bavry Anthony A AA North Florida/South Georgia Veterans Health System, Gainesville, FL; Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL. Electronic address: - - 2014
Endothelial dysfunction is highly prevalent and associated with adverse outcomes among patients without obstructive coronary artery disease (CAD). Angiotensin II inhibition may improve endothelial function, but with continued treatment, "aldosterone escape" may occur. Thus, it is unknown if adding aldosterone blockade further improves endothelial function. In a double-blind, parallel-group, repeated-measures ...
Kim Ji Won JW Department of Cardiovascular Medicine, Regional Cardiocerebrovascular Center, Wonkwang University Hospital, Iksan, - - 2014
High dose rosuvastatin loading before percutaneous coronary interventions (PCI) reduces the myocardial damage and the incidence of adverse cardiac events in patients with stable angina and acute coronary syndrome. However, no studies are present yet about rosuvastatin loading in patients with ST-segment elevation myocardial infarction (STEMI) in a primary PCI ...
Papai Gyorgy G Hungarian National Ambulance - - 2014
The efficacy of the transtelephonic ECG system (TTECG) in the management of ST segment elevation myocardial infarction (STEMI) was examined with regard to the ambulance service- and percutaneous coronary intervention (PCI)-related delay times, the prehospital medical therapy and the in-hospital mortality rate. The study was conducted as a collaborative effort ...
Oğuz Didem D Department of Cardiology, Faculty of Medicine, Başkent University; İstanbul-Turkey. - - 2014
This study aims to show the effect of myeloperoxidase (MPO), hsCRP, TNF-alpha values and leukocyte count on the development of coronary collateral arteries in patients with severely diseased coronary arteries. Current study is an observational cross-sectional study. In the study, 295 patients who had functional obstruction or total coronary occlusion ...
Assmus Birgit B Cardiology, Deptartment of Medicine III, Goethe University Frankfurt, Theodor-Stern-Kai 7, Frankfurt 60590, - - 2014
In the REPAIR-AMI trial, intracoronary infusion of bone marrow-derived cells (BMCs) was associated with a significantly greater recovery of contractile function in patients with acute myocardial infarction (AMI) at 4-month follow-up than placebo infusion. The current analysis investigates clinical outcome and predictors of event-free survival at 5 years. In the ...
Polizopoulou Zoe S ZS Diagnostic Laboratory, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, - - 2014
Cardiac troponin I (cTnI) is a biomarker correlated with the severity of myocardial injury. It is hypothesized that serial assessment of cTnI could provide information about the disease progression in chronic heart failure. The purpose of the study was to correlate serial serum cTnI concentrations with clinical scoring and select ...
Joffre Jérémie J Medical Intensive Care Unit, Cochin Hospital, Hôpitaux Universitaires Paris Centre, Assistance Publique des Hôpitaux de Paris, 27 rue du Faubourg Saint-Jacques, 75014 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Faculté de médecine, 15 rue de l'Ecole de Médecine, 75006 Paris, France; INSERM U970, Paris Cardiovascular Research Center (PARCC), European Georges Pompidou Hospital, 56 rue Leblanc, 75015 Paris, - - 2014
The leading cause of sudden cardiac death is myocardial ischemia. As for uncomplicated acute myocardial infarction (AMI), international guidelines plead for early coronary angiography with, in case of culprit lesion, angioplasty and stent implantation. However after cardiac arrest (CA), shock, hypothermia and changes in antiplatelet pharmacokinetic may promote stent thrombosis ...
Margonato Alberto A aCardiology and Coronary Intensive Care Unit bBone Metabolic Unit, Division of Cardiovascular Science, IRCCS S. Raffaele Hospital, Milan, - - 2014
To assess serum levels of the plaque calcification regulators osteoprotegerin (OPG) and Matrix Gla-proteins (MGP) in individuals with stable angina and acute myocardial infarction submitted to coronary angiography and their relation to coronary artery disease burden. The study included 40 individuals affected by ST-elevation myocardial infarction (STEMI) and 40 individuals ...
Manchurov Vladimir V Department of Cardiology, Moscow State University of Medicine and Dentistry, Moscow, - - 2014
Remote ischemic preconditioning (RIPC) by transient limb ischemia reduces myocardial ischemia-reperfusion injury in patients undergoing percutaneous coronary intervention (PCI). The aim of study we report here was to assess the effect of RIPC on endothelial function in patients with acute myocardial infarction (AMI) who underwent primary PCI. Forty eight patients ...
Ugur Murat M 1Clinic of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, - - 2014
The Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score (SS) was developed for evaluation of coronary artery disease complexity. We aimed to compare the SS calculated by conventional coronary angiography (CAG) and computed tomography angiography (CTA). Retrospectively, 107 patients were recruited (mean age 55.9 ± 12.4 ...
Conti Alberto A aAtrial Fibrillation Outpatient Clinic and Emergency Medicine bEmergency Medicine, Department of Critical Care Medicine and Surgery, cDysrhytmias Unit, Department of Cardiology, University of Florence, Careggi University Hospital, Florence, - - 2014
Patients with recent-onset atrial fibrillation (AF) and cardiac troponin I (cTnI) elevations show poor outcomes. Coronary heart disease might be a cause, consequence, or an innocent bystander. The aim of this study was to recognize and treat coronary heart disease to avoid adverse events. Patients with recent-onset AF participated in ...
Liu Yan-Li YL Department of Laboratory Medicine, Lianyungang Hospital Affiliated Bengbu Medical College, Lianyungang, Jiangsu 222006, P.R. - - 2014
When introduced into the infarcted heart, bone marrow‑derived mesenchymal stem cells (MSCs) prevent the heart from deleterious remodeling and improve its recovery. The aim of the present study was to investigate the effects of Ginkgo biloba extract (EGb) 761 on the infarcted myocardium microenvironment following MSC transplantation. The established rat ...
Fukunaga Masashi M From the Cardiovascular Division (M.F., K.F., D.K., H.S., K.M., H.T., T. Imanaka, T. Iwasaku, T.N., M.S., H.A., T.M.), Division of Coronary Heart Disease (M.M., M.O.), and Department of Radiology (K.K.), Hyogo College of Medicine, Nishinomiya, - - 2014
Despite a sufficient coronary blood flow after primary percutaneous coronary intervention for patients with ST-segment-elevation myocardial infarction; some patients have a poor outcome because of microcirculatory damage. This study evaluates whether the thermodilution-derived coronary blood flow parameters immediately after primary percutaneous coronary intervention predict early microvascular damage and midterm outcomes ...
Kwon Jin-Sook JS Research Laboratory of Cardiovascular Regeneration, Chonnam National University Hospital, Gwangju, - - 2014
We elucidated the therapeutic potential of human umbilical vein endothelial cells (HUVECs) for ameliorating progressive heart failure in a myocardial infarction (MI) rat model. MI was induced by ligation of left anterior descending artery, and HUVEC was transplanted 1week after MI. Cardiac function was evaluated by echocardiography, and histological analyses ...
Wardak Khalil S KS Broward County Medical Examiner and Trauma Services, 5301 S.W. 31st Avenue, Fort Lauderdale, FL, 33312, - - 2014
Drowning is a diagnosis of exclusion based on circumstantial and autopsy correlation. Sugimura proposed a threshold value of 14.1 for the Drowning Index (DI), the ratio of lung and pleural fluid to spleen weight, as a surrogate marker to diagnose drowning. We questioned the use of DI in diagnosing drowning. ...
Reddy Yeruva Madhu YM 1Division of Cardiovascular Diseases, Cardiovascular Research Institute, University of Kansas Hospital & Medical Center, Kansas City, - - 2014
-Data on relative safety, efficacy and role of different percutaneous left ventricular assist devices (pLVADs) for hemodynamic support during the ventricular tachycardia (VT) ablation procedure are very limited. -We performed a multicenter, observational study from a prospective registry including all consecutive patients (N=66) undergoing VT ablation with a pLVAD in ...
Chou Chu-Lin CL Institute of Medical Sciences, Tzu Chi University, Hualien, - - 2014
The outcomes of Chinese patients undergoing dialysis after coronary revascularization are unknown. We examined the outcomes of Taiwanese dialysis patients after coronary artery bypass grafting (CABG), percutaneous transluminal coronary angioplasty (PTCA), or coronary stenting. Using data from the National Health Institutes Research Database, we determined the outcomes of 1,287 dialysis ...
Türkmen Muhsin M aDepartment of Cardiology, Faculty of Medicine, Medipol University bDepartment of Cardiology, Kartal Kosuyolu Yuksek İhtisas Education and Research Hospital, Istanbul, - - 2014
The exact pathophysiology of slow coronary flow (SCF) phenomenon, characterized by delayed opacification of coronary arteries during coronary angiography, is still unknown, although endothelial dysfunction, inflammation, vasomotor disorders and atherosclerosis are shown. The present study was conducted to investigate whether there is a coagulation pathway abnormality in patients with SCF ...
Ma Jianying - - 2014
The objective of this study was to evaluate changes in left ventricular ejection fraction (LVEF) and left ventricular remodeling after coronary microembolization (CME) and to investigate the protective effects of methylprednisolone (MTP). CME was induced by injection of microspheres (42 mum Dynospheres) into left anterior descending artery of mini swine. ...
Nasseri Boris A BA Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, - - 2014
Intra-myocardial transplantation of CD133(+) bone marrow stem cells (BMC) yielded promising results in clinical pilot trials. We now performed the double-blinded, randomized, placebo-controlled CARDIO133 trial to determine its impact on left ventricular (LV) function and clinical symptoms. Sixty patients with chronic ischaemic heart disease and impaired LV function (left ventricular ...
Gokhroo R K RK Postgraduate Department of Cardiology, JLN Medical College & Associated Group of Hospitals, Ajmer 305 001, Rajasthan (India). - - 2014
Coronary sinus (CS) anatomy is a major predictor of successful implantation of left ventricular (LV) lead and procedural outcome. We therefore made an attempt to look at the CS anatomy and possible feasibility to classify them into categories depending upon their size, branching pattern, location of posterolateral vein (PLV), and ...
Lafci Gokhan G Departments of Cardiovascular Surgery (Drs. Kerim Cagli, Cicek, Diken, Gunertem, Lafci, and Yalcinkaya) and Cardiology (Drs. Kumral Cagli and Turak), Turkiye Yuksek Ihtisas Hospital, 06100 Ankara; Department of Cardiovascular Surgery (Dr. Korkmaz), Ankara Numune Education and Research Hospital, 06330 Ankara; and Department of Cardiovascular Surgery (Dr. Uzun), Ankara Education and Research Hospital, 06340 Ankara; - - 2014
Subvalvular apparatus preservation is an important concept in mitral valve replacement (MVR) surgery that is performed to remedy mitral regurgitation. In this study, we sought to determine the effects of papillary muscle repositioning (PMR) on clinical outcomes and echocardiographic left ventricular function in rheumatic mitral stenosis patients who had normal ...
Kishihara Jun J Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, - - 2014
We evaluated the effect of carvedilol, a beta-blocker with anti-oxidative action, against the atrial fibrillation (AF) inducibility, the development of atrial remodeling and the oxidative stress markers in a canine AF model. AF model was produced by performing 6-week rapid atrial stimulation in 15 dogs. The animals were divided into ...
Neves Laura M T LM Cardiovascular Physical Therapy Laboratory, Nucleus of Research in Physical Exercise, Universidade Federal de Sao Carlos, Sao Carlos, SP, - - 2014
Background: Reduced respiratory muscle endurance (RME) contributes to increased dyspnea upon exertion in patients with cardiovascular disease. Objective: The objective was to characterize ventilatory and metabolic responses during RME tests in post-myocardial infarction patients without respiratory muscle weakness. Method: Twenty-nine subjects were allocated into three groups: recent myocardial infarction group ...
Amuchastegui Tomas - - 2014
Disulfiram treatment for alcohol dependence is used with acceptable outcomes. By inhibiting the aldehyde dehydrogenase enzyme, this treatment increases acetaldehyde concentration after the ingestion of alcohol causing an unpleasant disulfiram-alcohol reaction. Typical symptoms include flushing, headache, nausea, vomiting, sweating, vertigo, and lightheadedness. However, there have also been descriptions of more ...
Miyata Makiko M Department of Cardiology and Hematology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, - - 2014
Sleep-disordered breathing (SDB) has a critical association with mortality and morbidity of patients with chronic heart failure (CHF). Troponin T is a marker of ongoing myocardial damage and predicts adverse clinical outcomes in patients with CHF. Carnitine plays an important role in the utilization of fatty acids in the myocardium. ...
Liu Ping P Department of Neurology, Xuanwu Hospital affiliated to Capital Medical University, Beijing, 100053, - - 2014
To discuss the correlation of tongue manifestation with the site of cerebral infarction in patients with acute cerebral infarction. From March 2008 to February 2009, 200 cases of hospitalized patients with first unilateral cerebral infarction were chosen in the Department of Neurology, Xuanwu Hospital. The correlation of different tongue color, ...
Ashida Terunao T Division of Cardiovascular Disease, The Institute for Adult Diseases Asahi Life - - 2014
We have recently demonstrated that basal cardiomyopathy develops in rabbits with ventricular tachyarrhythmias that have been induced by electrical stimulation of the cervical vagus. This study investigated whether similar basal cardiomyopathy would develop in rabbits with ventricular tachyarrhythmias induced by a single injection of adrenaline. Adrenaline was intravenously infused for ...
Yoshino Satoshi S Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and College of - - 2014
Background: Myocardial bridging (MB) results in compression of the coronary artery lumen in systole, extending into diastole with resultant hemodynamic alternation as reflected by fractional flow reserve (FFR). MB has also been associated with coronary endothelial dysfunction. The objective of this study was to investigate relationship between FFR with dobutamine challenge ...
Zhao X J XJ Department of Cardiology, Affiliated Hospital of Binzhou Medical University, Binzhou, - - 2014
The mechanisms of statins relieving the no-reflow phenomenon and the effects of single-dose statins on it are not well known. This study sought to investigate the effects of inflammation on the no-reflow phenomenon in a rabbit model of acute myocardial infarction and reperfusion (AMI/R) and to evaluate the effects of ...
Tanaka Akihito A Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan, - - 2014
Clopidogrel loading is a standard method to achieve rapid platelet inhibition and prevent thrombotic events. At the current time, little information is available to determine the effect of adjunctive cilostazol compared with clopidogrel loading. We retrospectively analyzed 212 patients undergoing primary percutaneous coronary intervention with drug-eluting stents for ST-segment elevation ...
Bajwa Hisham Z HZ Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, - - 2014
To provide direct evidence that mechanical obstruction of microvessels inhibits infarct resorption (healing) and enhances left ventricular (LV) remodeling using MRI. Animals (n = 20 pigs) served as controls (group I) or were subjected to either 90 min left anterior descending (LAD) coronary artery occlusion/reperfusion (group II) or 90 min ...
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