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Røpcke Dm - - 2013
Ischemic preconditioning (IPC) is known to protect tissue from ischemia and has effect both locally[i] and systemically[ii]. Remote IPC (RIPC) induced by limb ischemia provides systemic protection against prolonged ischemia in the target organ. RIPC has been reported to reduce infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing ...
Suehiro K - - 2013
BACKGROUND: /st>The aim of this study was to examine the ability of the Vigileo-FloTrac system to measure cardiac output (CO) and track changes in CO induced by increased vasomotor tone, under different states of systemic vascular resistance (SVR). METHODS: /st>Forty patients undergoing cardiac surgery were enrolled. Haemodynamic variables including CO ...
Chung Seungmin - - 2013
Electromagnetic interference (EMI) can affect various medical devices. Herein, we report the case of EMI from wireless local area network (WLAN) on an electrocardiogram (ECG) monitoring system. A patient who had a prior myocardial infarction participated in the cardiac rehabilitation program in the sports medicine center of our hospital under ...
Echeverri Dario - - 2013
The heart's venous drainage system has been the object of observations and research for several centuries. Its anatomic and histological characteristics, as well as its distribution and architecture, make the cardiac venous system a uniquely organized structure within the organism. An understanding of its physiology helps in comprehending some of ...
Hwang Joshua R - - 2013
BACKGROUND: Contrast-induced nephropathy (CIN) is an important cause of iatrogenic morbidity and mortality. The amount of contrast delivered has a major effect on CIN and is operator-dependent. A few studies suggested that the use of automated contrast injection systems is associated with reduced contrast volume. It is unknown whether this ...
Ibrahim Michael - - 2013
The t-tubule system in ventricular cardiomyocytes is essential for synchronous Ca(2+) handling, and therefore efficient contraction. T-tubular remodeling is a common feature of heart disease. In this review, we discuss whether t-tubular remodeling can be reversed and which factors may be implicated in this process. In particular, we focus on ...
Fosbøl Emil L - - 2013
Emergency medical services (EMS) are critical in the treatment of ST-segment elevation myocardial infarction (STEMI). Prehospital system delays are an important target for improving timely STEMI care, yet few limited data are available. Using a deterministic approach, we merged EMS data from the North Carolina Pre-hospital Medical Information System (PreMIS) ...
Goldfinger Judith Z - - 2013
Takotsubo cardiomyopathy is classically stress induced and characterized by regional wall motion abnormalities in the absence of coronary occlusion. It predominantly affects postmenopausal women; emotional and physical stressors can trigger the classic cardiomyopathic findings. These changes are likely mediated by catecholamines, which cause a distinctive pattern of ventricular dysfunction with ...
van Geldorp Irene E - - 2013
BACKGROUND: Patients treated by atrial redirection surgery (Senning or Mustard procedure) for transposition of the great arteries (TGA), have an important risk for heart failure caused by dysfunction of the systemic RV. Conventional non-systemic ventricular pacing (non-systVP) may even further increase this risk. OBJECTIVE: We investigated the effects of endocardial ...
Triggiani Vincenzo - - 2013
Thyroid hormones have relevant activity at cardiac and vascular level, by influencing heart rate, myocardial excitability as well as inotropic and lusitropic status, systemic vascular resistance and blood pressure. Moreover, they interact with neuro-hormonal systems such as sympathetic nervous system and renin-angiotensin-aldosterone system thus also indirectly influencing cardiovascular function. Due ...
Altay Hakan - - 2013
Heart failure (HF) is a clinical syndrome featuring cardiac pump failure along with signs and symptoms arising from salt and water retention mediated by activated renin-angiotensin-aldosterone system (RAAS). In addition to this cardiorenal perspective, HF is accompanied by a systemic illness, especially in advanced stages characterized by oxidative stress in ...
Yalta Kenan - - 2013
Neurohormones (NHs) in the cascade of the arginine vasopressin (AVP) system have drawn particular attention in the recent years. Copeptin, the C-terminal portion of provasopressin, is a novel NH of the AVP system, and is known to be co-released with AVP from hypothalamus (neurohypophysis). As a surrogate marker of the ...
Takeuchi Ichiro - - 2013
It is important for myocardial infarction patients to undergo immediate reperfusion of the affected coronary artery. In order to improve the prognosis, efforts to shorten the door to balloon time to within 90 minutes have been made. However, conventional methods such as faxing electrocardiograms (ECG) have not become widespread due ...
Liu Shing-Hong - - 2013
An automatic configuration that can detect the position of R-waves, classify the normal sinus rhythm (NSR) and other four arrhythmic types from the continuous ECG signals obtained from the MIT-BIH arrhythmia database is proposed. In this configuration, a support vector machine (SVM) was used to detect and mark the ECG ...
Paul Arghya - - 2013
Despite outstanding progress in the area of cardiovascular diseases, significant challenges remain in designing efficient delivery systems for myocardial therapy. Nanotechnology provides the tools to explore such frontiers of biomedical science at cellular level and thus offers unique features for potential application in the field of cardiac therapy. This chapter ...
Funk Duane J - - 2013
To provide a conceptual and clinical review of the physiology of the venous system as it is relates to cardiac function in health and disease. An integration of venous and cardiac physiology under normal conditions, critical illness, and resuscitation. The usual teaching of cardiac physiology focuses on left ventricular function. ...
Fedele Francesco F Department of Cardiovascular, Respiratory, Nephrology, Anesthesiology and Geriatric Sciences, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, - - 2013
Heart Failure (HF) is an acute or chronic syndrome, that causes a lot of damaging effects to every system. The involvement of different systems is variably related to age and others comorbidities. The severity of organ damage is often proportional to the duration of heart failure. The typology of HF ...
Praena-Segovia J J Internal Medicine Department, University Hospital Virgen del Rocío, Avenida Manuel Siurot s/n, 41013 Seville, - - 2013
Infiltrative heart diseases are caused by a heterogeneous group of disorders; amyloidosis and sarcoidosis are two frequent causes of myocardial infiltration, which differ in clinical and biological outcome and treatment issues. The presence of high levels of angiotensin-converting enzyme (ACE) in a patient with infiltrative heart disease may increase suspicion ...
Martínez-Pérez Borja B University of Valladolid, Department of Signal Theory and Communications, and Telematics Engineering, University of Valladolid, Valladolid, Spain. - - 2013
Cardiovascular diseases are the deadliest diseases worldwide, with 17.3 million deaths in 2008 alone. Among them, heart-related deaths are of the utmost relevance; a fact easily proven by the 7.25 million deaths caused by ischemic heart disease alone in that year. The latest advances in smartphones and mHealth have been ...
Watanabe Shogo - - 2012
Background: Endothelial dysfunction and autonomic nervous system imbalance are both risk markers of atherosclerotic vascular damage. The relationship between these 2 factors, however, has not been clarified concisely. Methods and Results: Flow-mediated dilation (FMD) was measured in 47 patients with ischemic heart disease (IHD; mean age, 68.1±7.1 years) using an ultrasound semi-automatic ...
Kokorin Valentin A - - 2012
Acute myocardial infarction is still considered as one of the most threatening disorders in internal medicine. Numerous complications of infarction develop due to activation of different neurohumoral systems. The article discusses modern methods of pharmacological correction of neurohumoral system activity in various stages of myocardial infarction. It is emphasized that ...
James Stacy H - - 2012
Drugs that work on the hematologic system play an important role in helping to limit the morbidity and mortality that can be associated with an acute coronary syndrome. The pharmacology of the fibrinolytic agents, thrombin inhibitors, and antiplatelet agents is described. A case study of a woman having an ST-segment ...
Meisel Simcha Ron - - 2012
Collaterals to occluded coronary arteries have been observed early after the onset of acute myocardial infarction (AMI). The pressure distal to the occluded segment of the culprit coronary artery (P(d)) is generated by collateral flow from the feeding coronary artery supplied by the systemic circulation. The aim of the study ...
Blumenstein Johannes - - 2012
Transapical aortic valve implantation (TA-AVI) has evolved as a treatment option for high-risk patients who have severe aortic stenosis. The aim of this study was to evaluate the feasibility of a novel apical closure device to allow for standardized apical access and closure. The Apica ASC system consists of three ...
Xhyheri Borejda - - 2012
Heart rate variability (HRV) non-invasively assesses the activity of the autonomic nervous system. During the past 30 years, an increasing number of studies have related the imbalance of the autonomic nervous system (as assessed by HRV) to several pathophysiogical conditions, particularly in the setting of cardiovascular disease. Sudden death, coronary ...
Ciosek Joanna - - 2012
Background: Pineal and melatonin interactions with the hypothalamo-neurohypophysial system are well documented. In addition, vasopressin and oxytocin secretion are known to be part of the neuroendocrine response to chronic heart failure evoked by myocardial infarction. The present study was undertaken to evaluate the possible regulatory role of melatonin in the ...
Mentz Robert J RJ Duke University Medical Center, Durham, NC 27710, USA. - - 2013
The renin-angiotensin aldosterone system (RAAS) is central to the pathogenesis of cardiovascular disease. RAAS inhibition can reduce blood pressure, prevent target organ damage in hypertension and diabetes, and improve outcomes in patients with heart failure and/or myocardial infarction. This review presents the history of RAAS inhibition including a summary of ...
Tchantchaleishvili Vakhtang - - 2012
Ventricular assist devices emerged as a widely used modality for treatment of end-stage heart failure; however, despite significant advances, external energy supply remains a problem contributing to significant patient morbidity and potential mortality. One potential solution is using the nuclear radioisotope Plutonium-238 as a power source. Given its very high ...
Ostadal Petr - - 2012
BACKGROUND: -Several percutaneous circulatory support systems have been recently introduced into clinical practice for the treatment of cardiogenic shock or refractory non-tolerated ventricular tachycardia, in support of high-risk catheter interventions and occasionally, cardiopulmonary resuscitation. To date, however, a direct comparison of the available systems has not been performed. METHODS AND ...
Balaj Raluca - - 2012
Primary myocardial involvement is common in systemic sclerosis and affects the prognosis of the disease when it is clinically evident. The exact mechanism leading to the myocardial fibrosis in systemic sclerosis remains unknown. Its detection depends, at least in part, on the sensitivity of the diagnostic methods used. The aim ...
Lønborg Jacob - - 2012
The association between reperfusion delay and myocardial damage has previously been assessed by evaluation of the duration from symptom onset to invasive treatment, but results have been conflicting. System delay defined as the duration from first medical contact to first balloon dilatation is less prone to bias and is also ...
Nazar André - - 2012
BACKGROUND AND AIMS: The current study was aimed to assess the potential role of cardiac abnormalities in the pathogenesis of circulatory and renal dysfunction in cirrhosis. METHODS: One hundred and fifty two patients (34 without ascites, 95 with ascites without renal failure and 21 with hepatorenal syndrome) were evaluated using ...
Godiwala Tapan - - 2012
Approximately 330,000 ST-elevation myocardial infarctions (STEMI) occur yearly in the United States. Emergent reperfusion is the cornerstone of STEMI therapy and the key to restoration of coronary blood flow in an infarct-related vessel. Reperfusion methods include thrombolysis, primary percutaneous coronary intervention, or both methods combined. Selection of the appropriate reperfusion ...
Marti Catherine N - - 2012
Outcomes for heart failure (HF) patients remain suboptimal. No known therapy improves mortality in acute HF and HF with preserved ejection fraction; the most recent HF trial results have been negative or neutral. Improvement in surrogate markers has not necessarily translated into better outcomes. To translate breakthroughs with potential therapies ...
Dm Røpcke - - 2012
Ischemic preconditioning (IPC) is known to protect tissue from ischemia and has effect both locally[] and systemically[]. Remote IPC (RIPC) induced by limb ischemia provides systemic protection against prolonged ischemia in the target organ. RIPC has been reported to reduce infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing ...
Bonini Rômulo César Arnal - - 2012
Patient 75, years-old, with free wall rupture of the right ventricle, corrected with prolene 3.0 points anchored in bovine pericardium patch, promoting the closure of the rupture. The patient was discharged on the 59th day after surgery in good clinical ans laboratorial conditions.
Santos José Wilson Dos - - 2012
BACKGROUND: The influence that myocardial bridge exercises over blood stream in the course of arterial segment under the bridge has been discussed by the scientific community. OBJECTIVE: To compare ultrastructural muscle tissue of myocardial bridge and the ventricular wall; to analyze the degree of injury to the tunica intima of ...
Mateev Hristo - - 2012
Purpose. To evaluate the clinical applicability of a telemonitoring system: telemetric system for collection and distant surveillance of medical information (TEMEO). Methods. We evaluated 60 patients, applying simultaneously standard Holter ECG and telemonitoring. Two different comparisons were performed: (1) TEMEO ECG with standard 12-lead ECG; (2) TEMEO Holter with standard ...
Jensen Bjarke - - 2012
The endothermic state of mammals and birds requires high heart rates to accommodate the high rates of oxygen consumption. These high heart rates are driven by very similar conduction systems consisting of an atrioventricular node that slows the electrical impulse and a His-Purkinje system that efficiently activates the ventricular chambers. ...
Narain Sachin S Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, 1611 NW 12th Avenue (C-301), Miami, FL 33136, - - 2012
A 31-year-old male was transferred to our hospital with severe heart failure due to viral myocarditis. He progressed to multiorgan failure requiring intubation and maximal doses of multiple vasopressors. Circulatory support was provided with an Impella device as a bridge to an extracorporeal membrane oxygenation (ECMO) system. On full mechanical ...
Soares Mauro Pereira - - 2011
The current study reports the investigation on the cause of sudden deaths associated with cardiac fibrosis in cattle in northern Rio Grande do Sul, Brazil. The exclusion of known causes of bovine cardiac fibrosis as well as the absence of the plants in that region whose consumption has already been ...
Vera Janavel Gustavo L - - 2011
BACKGROUND: In large mammalian models of acute myocardial infarction (AMI), plasmid-mediated vascular endothelial growth factor (pVEGF) gene transfer has been shown to induce angio-arteriogenesis, proliferation of myocyte precursors and adult cardiomyocyte mitosis, reducing infarct size at 15 days after coronary artery occlusion. However, it is unknown whether these effects persist at ...
Xu Weixian W Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, United - - 2011
The fundamental relationship between blood disorders and the cardiovascular system originates within multiple points of interface, ranging from the heart and its structural constituents to include heart chambers, valves, coronary arteries, coronary veins, and the cerebrovascular and peripheral vasculature. While the cellular components of circulating blood derive their primary origin ...
Kojouri Ga - - 2011
The role of minerals on parasite persistency and the interaction between minerals and animal responses to the parasite infestation is not clear. For these reasons, the present research was aimed to compare copper, zinc and iron status in sheep with parasitic myocarditis and healthy ones in 2009. Blood and heart ...
Taylor Jennifer - - 2011
Famous for the development of electrophysiology, the Duke Heart Center has grown from a regional centre to one of international importance
Gorst-Rasmussen Anders - - 2011
Principal component analysis (PCA) has been used extensively in the field of nutritional epidemiology to derive patterns that summarize food and nutrient intake, but interpreting it can be difficult. The authors propose the use of a new statistical technique, the treelet transform (TT), as an alternative to PCA. TT combines ...
Tuzun Egemen - - 2011
Purpose. To provide an ovine model of ventricular remodeling and reverse remodeling by creating congestive heart failure (CHF) and then treating it by implanting a left ventricular assist device (LVAD). Methods. We induced volume-overload heart failure in 2 sheep; 20 weeks later, we implanted an LVAD and assessed recovery 11 ...
Siegenthaler N - - 2011
After the implantation of a biventricular assist device hemodynamic evaluation is difficult. The device itself frequently does not report the real outflow as it does not take into account the native cardiac output. Other methods used for cardiac output measurements cannot be employed for technical reasons and/or because their measurements ...
Tutschek Boris - - 2011
Fetal echocardiography was initially used to diagnose structural heart disease, but recent interest has focused on functional assessment. Effects of extracardiac conditions on the cardiac function such as volume overload (in the recipient in twin-twin transfusion syndrome), a hyperdynamic circulation (arterio-venous malformation), cardiac compression (diaphragmatic hernia, lung tumours) and increased ...
Cox Georgina K - - 2010
In the absence of any previous study of the cardiac status of hagfishes during prolonged anoxia and because of their propensity for oxygen-depleted environments, the present study tested the hypothesis that the Pacific hagfish Eptatretus stoutii maintains cardiac performance during prolonged anoxia. Heart rate was halved from the routine value ...
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