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Results 301 - 350 of 1707
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Verrijcken Anton - - 2011
Sometimes, a clinical course that initially appears to be 'classic' turns out to be a manifestation of a rare disease. We report on a 62-year-old woman who presented initially with episodic headache, followed by cardiogenic shock. What was first thought to be an ST-segment elevation acute myocardial infarction, later to ...
Recupero Antonino - - 2010
Recently, new cardiac imaging techniques as cardiac magnetic resonance have shown to play a primary role for a recognition of unusual mechanisms of right and left ventricular obstruction. However, echocardiography remains the most widely used technique and the first step to recognize myocardial hypertrophy, blood flow velocity, and pressure gradients ...
Eitel Ingo - - 2010
Takotsubo cardiomyopathy (TTC) is a new clinical entity characterised by acute but rapidly reversible left ventricular systolic dysfunction. This case report demonstrates the unique finding of a complete normalization of left ventricular function in a patient with TTC in only 36 h documented by cardiac magnetic resonance imaging. To our best ...
Singh Nishith K - - 2010
BACKGROUND: Stress cardiomyopathy (SCM) is a newly described reversible cardiomyopathy of largely unclear etiology. We studied SCM in a large cohort to gain further insights. METHODS: We retrospectively identified 114 cases of SCM from among 12,150 consecutive North American patients diagnosed as Troponin-positive acute coronary syndrome, from January 2000 through ...
Maro, EE; ;
Background: Peripartum cardiomyopathies are endemic in Sub-Sahara Africa, causing a high morbidity and mortality. The effect of the recent introduction of Angiotensin converting enzyme inhibitors [ACEI] and beta-adrenergic blockers in the treatment of heart failure is not well known in patients with peripartum cardiomyopathy in our set up. Objective: To ...
Kim Dong Hun - - 2010
Takotsubo cardiomyopathy is characterised by reversible left ventricular apical ballooning and no significant coronary artery stenosis. A new variant, a mid-ventricular pattern of takotsubo cardiomyopathy, has been reported. However, there have been few reports on basal wall akinesia or hypokinesia with preservation of the apical and mid-ventricular wall motion shown ...
Dandel Michael - - 2009
A case is presented of initially unrecognized takotsubo cardiomyopathy with a dramatic clinical course after emergency catecholamine treatment for circulatory support during stress-induced cardiac syncope followed by complete recovery of cardiac function after catecholamine withdrawal and starting beta-blocker therapy. Echocardiography including 2D-strain imaging suggested that the left ventricle (LV) wall ...
Ker James - - 2009
Originally described by Brock and Teare, today hypertrophic cardiomyopathy is clinically defined as left (or right) ventricular hypertrophy without a known cardiac or systemic cause, such as systemic hypertension, Fabry's disease or aortic stenosis.Also appreciated today is the enormous genotypic and phenotypic heterogeneity of this disease with more than 300 ...
Dorfman Todd A - - 2009
Takotsubo cardiomyopathy (TC) is characterized by transient, often severe, left ventricular dysfunction and electrocardiographic changes that might mimic acute myocardial infarction in the absence of significant obstructive coronary artery disease. It is often encountered in elderly women after physical or emotional stress. Excessive catecholamine stimulation, metabolic abnormalities, and microcirculatory dysfunction ...
Al-Mallah Mouaz - - 2009
Cardiovascular magnetic resonance (CMR) imaging is an important clinical tool that aids in the diagnosis and management of patients with cardiomyopathy. With its ability to assess morphologic and physiologic myocardial characteristics in the same imaging session, CMR can effectively rule out less common causes of cardiomyopathy, including cardiac hemochromatosis, amyloidosis, ...
Yu Jiashing - - 2009
OBJECTIVES: Various approaches to myocardial reconstruction have been developed for the treatment of congestive heart failure resulting from ischemic cardiomyopathy. METHODS: In this study we determined whether in situ application of polymers could reshape left ventricular geometry in a chronic rodent model of ischemic cardiomyopathy. RESULTS: We demonstrate that alginate ...
Velazquez-Ceceña José-Luis E - - 2009
Dynamic left ventricular outflow tract (LVOT) obstruction is seen classically in hypertrophic cardiomyopathy. Cardiac amyloidosis can present with asymmetric hypertrophy that resembles hypertrophic cardiomyopathy, and, in some cases, with dynamic LVOT obstruction. The occurrence of syncope in such patients is not uncommon. The syncope is usually thought to be related ...
Gilljam Thomas - - 2009
Transplant indications for right ventricular (RV) cardiomyopathy have not been defined. We report on two boys, aged 18 and 17 years, one with arrhythmogenic right ventricular cardiomyopathy (ARVC) and one with Uhl's anomaly. Both had implantable cardioverter defibrillator (ICD) for the prevention of sudden death (SD), but were not considered ...
Papaioannou Georgios I - - 2009
Arrhythmogenic right ventricular cardiomyopathy is an inherited myocardial disease affecting predominantly young people and manifests as sustained ventricular tachycardia with left bundle branch block morphology, sudden death or isolated right or biventricular heart failure. However, its first manifestation as sustained ventricular tachycardia in older patients without preceding symptoms of heart ...
Dal-Bianco Jacob P - - 2009
The clinical recognition of constrictive pericarditis (CP) is important but challenging. In addition to Doppler echocardiography, newer echocardiographic techniques for deciphering myocardial deformation have facilitated the noninvasive recognition of CP and its differentiation from restrictive cardiomyopathy. In a patient with heart failure and a normal ejection fraction, echocardiographic demonstration of ...
Mahmoudabady Maryam - - 2009
BACKGROUND: Insulin-like growth factor-1 (IGF-1), transforming growth factor beta (TGFbeta) and cyclins are thought to play a role in myocardial hypertrophic response to insults. We investigated these signaling pathways in canine models of ischemic or overpacing-induced cardiomyopathy. METHODS: Echocardiographic recordings and myocardial sampling for measurements of gene expressions of IGF-1, ...
Ker J J Department of Physiology, University of Pretoria, Pretoria. - - 2009
During the past three decades, every aspect of cardiomyopathy has undergone dramatic change. When examining the literature on the physiological aspects of the failing heart, one immediately recognises that South Africa has made a contribution: Brink, Bester and Lochner evaluated the possible therapeutic aspects of the Bowditch phenomenon and myocardial ...
Berry Mathieu - - 2009
Takotsubo cardiomyopathy is usually described following acute emotional stress. We report here the case of a 48-year-old woman admitted for acute coronary syndrome after an intensive squash match. Diagnosis of Takotsubo cardiomyopathy due to acute physical stress was suspected in presence of normal coronary arteries and transitory left ventricular dysfunction ...
Popov Aron F - - 2009
We report an unusual case of a 32-year old man who was treated for a hypertrophic obstructive cardiomyopathy (HOCM) with a DDD pacing with short AV delay reduction in the past. Without prior notice the patient developed ventricular fibrillation and an invasive cardiac diagnostic was performed, which revealed a myocardial ...
Khouri Samer - - 2009
Due to the rise in the number of reports of stress cardiomyopathy in the literature, awareness of this condition is increasing. Although different names have been used to describe this condition, the similarities in clinical, electrocardiographic, echocardiographic, and angiographic features suggest that they represent the same spectrum of diseases with ...
Kim Il-Man - - 2009
Recent work has demonstrated that Drosophila can be used as a model of dilated cardiomyopathy, defined as an enlarged cardiac chamber at end-diastole when the heart is fully relaxed and having an impaired systolic function when the heart is fully contracted. Gene mutations that cause cardiac dysfunction in adult Drosophila ...
Kodama Sunao - - 2009
The present report describes two female patients aged 39 and 57 years who experienced loss of consciousness and chest pain due to high-grade atrioventricular block. Both patients demonstrated noncontraction centred on the cardiac apex and excessive contraction at the cardiac base on cardiac ultrasonography and left ventriculography, but neither of ...
Gotyo Naoki - - 2009
We describe here a patient with torsade de pointes associated with recurrent ampulla cardiomyopathy, who was later proven to suffer from idiopathic AC TH deficiency. A 70-year-old man was admitted to our hospital for bacterial pneumonia. A cardiac examination performed on admission revealed ampulla cardiomyopathy, which improved spontaneously as the ...
Lamhonwah Anne Marie - - 2009
Organic cation/carnitine transporters transport carnitine, drugs, and xenobiotics (e.g. choline, acetylcarnitine, quinidine, and verapamil), and are expressed in muscle, heart, blood vessels, etc. To characterize expression patterns of mOctn1, -2, and -3 in adult murine heart, we applied our transporter-specific antibodies to mOctn1, -2, and -3, followed by secondary antibody ...
Alexoudis A K - - 2009
Arrhythmogenic right ventricular dysplasia, also called right ventricular cardiomyopathy, is a genetically determined heart muscle disease, characterised by life-threatening ventricular arrhythmias in apparently healthy young people. The primary myocardial pathology is that the myocardium of the right ventricular free wall is replaced by fibrous or fibrofatty tissue, with scattered residual ...
Kurt Ibrahim Halil - - 2009
Tako-tsubo cardiomyopathy is a syndrome mostly observed in post-menopausal women, which mimics myocardial infarction with an ST elevation; and coronary angiography shows apical ballooning but a normal left anterior descending. Although coronary artery disease is considered as an exclusion criterion, for differential diagnosis of this type of cardiomyopathy, Tako-tsubo cardiomyopathy ...
Sen-Chowdhry Srijita S Inherited Cardiovascular Disease Group, The Heart Hospital, London, United Kingdom. - - 2008
We sought to investigate the clinical-genetic profile of left-dominant arrhythmogenic cardiomyopathy (LDAC). In the absence of coronary disease and left ventricular (LV) systolic dysfunction, lateral T-wave inversion and arrhythmia of LV origin are often considered benign. Similarly, chest pain with enzyme release might be attributed to viral myocarditis. We hypothesized ...
Choudhary Anwar S - - 2009
We report a case of dilated cardiomyopathy that we believe is secondary to excessive use of inhaled beta agonists. Clinicians should be mindful of this possibility when using beta agonists to treat patients with obstructive airways disease; particularly if there is already recognised left ventricular dysfunction.
Fukuzawa Koji - - 2009
We describe a case of a 60-year-old male with dilated phase of hypertrophic cardiomyopathy caused by Fabry disease. He was diagnosed to have a cardiac variant of Fabry disease by an enzyme assay and a right ventricular endomyocardial biopsy which revealed specific features of this disease and cardiac involvement was ...
Sliwa Karen - - 2008
Peripartum cardiomyopathy (PPCM) is a form of heart failure that occurs in women within 1 month of predelivery and 5 months postdelivery. Echocardiography demonstrates features of cardiomyopathy with impaired ejection fraction; global dilatation and thinned-out walls are sometimes present. The symptoms and signs of PPCM are similar to those in ...
Sherrid M V - - 2008
It is now 50 years since the modern description of hypertrophic cardiomyopathy (HCM). The initial descriptions foretold the current efforts towards sudden death prevention, alleviation of heart failure symptoms and angina, relief of left ventricular outflow tract obstruction, preparticipation athletic screening, family screening and genetic testing. The authors review the ...
Kassim Thaslim Ahamed - - 2008
OBJECTIVE: To review the pathogenesis as well as the clinical and laboratory features of catecholamine-induced cardiomyopathy associated with pheochromocytoma and other disorders and discuss the various treatment options available. METHODS: Materials used for this article were identified through MEDLINE, PubMed, and Google Scholar searches of the relevant literature from 1955 ...
Soufen H N - - 2008
Cardiac interstitial fibrosis may contribute to ventricular dysfunction and the prognosis of patients with dilated cardiomyopathy. The objective of the present study was to determine if total myocardial collagen content and collagen type III/I (III/I ratio) mRNAs differ in hypertensive, alcoholic, and idiopathic dilated cardiomyopathy subjects. Echocardiography and exercise cardiopulmonary ...
Elkhateeb Osama E - - 2008
Transient apical ballooning syndrome, or takotsubo cardiomyopathy is a syndrome characterized by reversible dilation of the left ventricular apex. It usually occurs in response to stress, and resolves completely in a few weeks. The present report describes a 55-year-old woman who presented with chest pain and syncope in response to ...
Kim Luke - - 2008
Two patients presented with takotsubo cardiomyopathy after chemotherapy. Neither of the patients had any known cardiac history until the initiation of chemotherapy. These patients were treated with different chemotherapy regimens appropriate to their malignancies. After chemotherapy initiation, they presented with symptoms ranging from exertional dyspnea to cardiogenic shock requiring intra-aortic ...
Popović Zoran B - - 2008
The relationship among myocardial fibrosis, segmental strains, and hypertrophic cardiomyopathy (HCM) in patients with preserved left ventricular ejection fraction is not known. We evaluated this relationship in 39 consecutive patients with HCM with transthoracic echocardiography and delayed hyperenhancement magnetic resonance imaging 20 minutes after injection of 0.2 mmol/kg of gadolinium. ...
Franqui-Rivera Hilton - - 2008
Non-compaction of the left ventricle is an extremely rare cardiomyopathy resulting from a defective morphogenesis of the endomyocardium. It results in an architecturally aberrant ventricular wall consisting of two layers: a compacted layer and a loose interwoven meshwork with prominent trabeculae and deep intertrabecular recesses that communicate with the left ...
Yamada Takumi - - 2009
We report two cases undergoing electrophysiological studies for ventricular arrhythmias (VAs) associated with peripartum cardiomyopathy. Those two cases demonstrated that subsequent pregnancies might result in deterioration of VAs even though they exhibit no symptoms of heart failure. Those findings may clinically impact the decision making when women with a history ...
Zheng Ming - - 2009
Accumulating data suggest a link between alterations/deficiencies in cytoskeletal proteins and the progression of cardiomyopathy and heart failure, although the molecular basis for this link remains unclear. Cypher/ZASP is a cytoskeletal protein localized in the sarcomeric Z-line. Mutations in its encoding gene have been identified in patients with isolated non-compaction ...
Fyfe Billie - - 2010
A patient with hypertrophic obstructive cardiomyopathy (HOCM) and an unusual right ventricular mural pattern of endocarditis that clinically mimicked a neoplasm is presented. To our knowledge, this is the first report of right ventricular mural endocarditis complicating HOCM.
Weis Florian - - 2009
A young woman suffering from congenital hypertrophic obstructive cardiomyopathy (HOCM) received a transcoronary ablation of the septal hypertrophy (TASH) and an automated Cardioverter/Defibrillator (AICD) for the relief of progressive symptoms of heart failure. She developed an acute heart failure in the perioperative period and had to be put on veno-arterial ...
Jayaraman L L Department of Anesthesiology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India. - - 2010
The aim of this study was to describe the clinical features and management of Takotsubo cardiomyopathy manifesting during the intraoperative period in a patient undergoing laparoscopic cholecystectomy. a 29-year-old ASA I female patient was posted for laparoscopic cholecystectomy. A standard general anesthetic technique was followed. Two minutes after the initiation ...
Jayaraman L - - 2008
The aim of this study was to describe the clinical features and management of Takotsubo cardiomyopathy manifesting during the intraoperative period in a patient undergoing laparoscopic cholecystectomy. Clinical features: a 29-year-old ASA I female patient was posted for laparoscopic cholecystectomy. A standard general anesthetic technique was followed. Two minutes after ...
Nodari Savina - - 2009
BACKGROUND: N-3 polyunsaturated fatty acids (n-3 PUFAs) intake is associated with a reduction in sudden cardiac death in patients with ischemic heart disease. Their effects in patients with heart failure caused by idiopathic dilated cardiomyopathy (IDC) are unknown. METHODS: We compared with placebo the effects of n-3 PUFAs administration in ...
Wani Sunil - - 2008
The pathophysiology of takotsubo cardiomyopathy remains enigmatic. Here we attempted to define the link between the coronary arteries and the histopathological involvement of the left ventricle. We observed similarities and discrepancies between patients. All patients experienced stress prior to the event. We found a reduced coronary flow reserve in all ...
Collen Jacob - - 2008
Catecholamine-induced cardiomyopathy has been recognized for decades. We present the case of a 21-year-old female referred for an electrophysiologic (EP) study who underwent an infusion of isoproterenol and epinephrine in an attempt to unmask an ectopic atrial tachycardia. Prior to leaving the study suite, the patient started complaining of chest ...
Dolci Alberto - - 2008
Chemotherapy is a well-established therapeutic approach for several malignancies, but its clinical efficacy is often limited by its related cardiotoxicity, which leads to cardiomyopathy, possibly evolving into heart failure. To detect cardiac damage, the adopted diagnostic approach is the estimation of left ventricular ejection fraction by echocardiography. This approach shows ...
Zubrinich C M - - 2008
Tako-tsubo-like cardiomyopathy is characterized by acute chest pain, electrocardiographic changes and increased cardiac enzymes in the absence of obstructive coronary vessel disease. We describe the development of tako-tsubo-like cardiomyopathy in an elderly woman after the use of an EpiPen for generalized urticaria and angioedema. As adrenaline may participate in the ...
Dereddy Narendra R - - 2008
Rhabdomyomas are the most common cardiac tumours in children. They sometimes cause significant obstruction of the ventricular out flow tracts. We report a series of 3 neonates diagnosed antenatally with multiple rhabdomyomas, who developed significant obstruction of the ventricular outflow tracts following birth. They underwent surgical resection in the neonatal ...
Jaber W A - - 2009
OBJECTIVES: To examine whether percutaneous alcohol septal ablation affects coronary flow reserve (CFR) in patients with hypertrophic cardiomyopathy (HCM). METHODS: CFR was measured immediately before and after septal ablation in patients with symptomatic obstructive HCM. CFR was also obtained in normal subjects (NL) for comparison. RESULTS: Patients with HCM (n ...
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