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Higuchi Yoshiharu Y Division of Cardiology, Department of Medicine, Nihon University School of - - 2014
Periprocedural myocardial infarction (PMI) is one of the major complications of percutaneous coronary intervention (PCI). We investigated the influence of coronary plaque burden and characteristics on PMI using intravascular ultrasound (IVUS) with radiofrequency-based tissue characterization technology (iMAP). The study population consisted of 33 consecutive patients with stable angina pectoris who ...
Tamura Akira A Akira Tamura, Department of Cardiology and Clinical Examination, Oita University, Yufu 879-5593, - - 2014
The 12-lead electrocardiogram (ECG) is a crucial tool in the diagnosis and risk stratification of acute coronary syndrome (ACS). Unlike other 11 leads, lead aVR has been long neglected until recent years. However, recent investigations have shown that an analysis of ST-segment shift in lead aVR provides useful information on ...
Rastgou Fereydoon F Department of Nuclear Medicine and Molecular Imaging, Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences, Vali-e-Asr Ave., Niayesh Blvd., Tehran, - - 2014
Recently, the phase analysis of gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) has become feasible via several software packages for the evaluation of left ventricular mechanical dyssynchrony. We compared two quantitative software packages, quantitative gated SPECT (QGS) and Emory cardiac toolbox (ECTb), with tissue Doppler imaging (TDI) ...
Yan Liru L Department of Geriatric Outpatient, The Fourth Affiliated Hospital of Harbin Medical University, 37 Yiyuan Road, Nangang District, Harbin, 150001, Heilongjiang Province, - - 2014
Uric acid (UA) is generalized as a byproduct the terminal steps of purine catabolism, which are catalyzed by xanthine oxidoreductase. Xanthine oxidase activity and uric acid synthesis are reported to be increased under tissue ischemia. Therefore, elevated uric acid may act as a prognostic marker of acute myocardial infarction (AMI). ...
Vélez P - - 2014
Membrane microvesicles (MVs) are released from activated cells, most notably platelets, into the circulation. They represent an important mode of intercellular communication, and their number is increased in patients with acute coronary syndromes. We present here a differential proteomic analysis of plasma MVs from ST-elevation myocardial infarction (STEMI) patients and ...
Favaretto Enrico E Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, - - 2014
Clinical benefit of postconditioning in patients with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention is still controversial. We performed a meta-analysis of available randomized clinical trials (RCTs) to define the role of postconditioning in STEMI. Fourteen RCTs evaluating postconditioning in a total of 778 patients with STEMI ...
Haberka Maciej M 2nd Department of Cardiology, Medical University of Silesia, Katowice, - - 2014
The aim of the study was to evaluate the left ventricle (LV) function with speckle tracking echocardiography (STE) and to assess its relation to prognosis in patients after acute myocardial infarction (AMI). Sixty-three patients (F/M = 16/47 pts; 62.33 ± 11.85 years old) with AMI (NSTEMI/STEMI 24/39 pts) and successful percutaneous coronary intervention (PCI) with ...
de Jonge M M Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The - - 2014
This study analyzes the efficacy in myocardial protection of two types of cardioplegia solutions, namely, blood and crystalloid cardioplegia, both given intermittently in patients undergoing coronary artery bypass grafting (CABG). Adult patients undergoing primary isolated coronary artery bypass grafting between January 1998 and January 2011 with cardiopulmonary bypass, using either ...
Wen Dan D Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung & Blood Vessel Diseases, Beijing 100029, - - 2014
Several studies have reported that Connexin37 (Cx37) gene C1019T polymorphism is associated with myocardial infarction (MI) and coronary artery disease (CAD). However, the results remain contradictory. Pubmed, Embase, and Cochrane library databases were systemically searched. Data were extracted by two independent reviewers and pooled odds ratio (OR) with 95% confidence ...
Zangrando Jennifer - - 2014
Long non-coding RNAs (lncRNAs) constitute a novel class of non-coding RNAs. LncRNAs regulate gene expression, thus having the possibility to modulate disease progression. In this study, we investigated the changes of lncRNAs expression in the heart after myocardial infarction (MI). Adult male C57/BL6 mice were subjected to coronary ligation or ...
Kobayashi Nobuaki N aNew York Presbyterian Hospital/Columbia University Medical Center bClinical Trials Center, Cardiovascular Research Foundation, New York, New York cBoston Scientific Corporation, Natick, Massachusetts dDepartment of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio eVascular Therapies, Covidien fGeorgetown University, Washington, District of Columbia gMedStar Health Research Institute, Hyattsville, Maryland, USA hAmper Kliniken AG, Dachau, Germany iCardiology Department, Auckland City Hospital, Auckland, New Zealand jInterventional Cardiology Unit, Ospedale Papa Giovanni XXIII, Bergamo, - - 2014
To investigate the difference in neointimal hyperplasia (NIH) between ST-segment elevation myocardial infarction (STEMI), stable angina pectoris (SAP), and unstable angina pectoris (UAP). From formal core laboratory intravascular ultrasound substudies, we compared NIH after paclitaxel-eluting stents (PES) or bare metal stents (BMS) in STEMI lesions from HORIZONS-AMI trial with SAP ...
Iwasaki Toshitaka T Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health - - 2014
Heart Score View (HSV) is a free software package for automated quantification of myocardial single photon emission computed tomography (SPECT) imaging using a standard Windows computer. We compared scoring results of myocardial perfusion among visual analysis, Quantitative Perfusion SPECT (QPS), and HSV in patients with known or suspected coronary artery ...
Compas Colin B - - 2014
Quantitative analysis of left ventricular deformation can provide valuable information about the extent of disease as well as the efficacy of treatment. In this work, we develop an adaptive multi-level compactly supported radial basis approach for deformation analysis in 3D+time echocardiography. Our method combines displacement information from shape tracking of ...
Matchett Gerald G Department of Anesthesiology & Pain Management, University of Texas-Southwestern Medical Center, 5323 Harry Hines Blvd., M.C. 9068, Dallas, Texas 75390-9068, - - 2014
The human heart normally exhibits robust beat-to-beat heart rate variability (HRV). The loss of this variability is associated with pathology, including disease states such as congestive heart failure (CHF). The effect of general anesthesia on intrinsic HRV is unknown. In this prospective, observational study we enrolled 100 human subjects having ...
MacFadyen R J RJ RJ MacFadyen Ballarat Health and University of Melbourne Ballarat VIC 3350 Australia. Email - - 2014
Title: Off hour presentation and outcomes in patients with acute myocardial infarction: systematic review and meta-analysis; Authors: Sorita A, Ahmed A, Starr S et al; Journal: BMJ 2014; 348; f7393. http://dx.doi.org/10.1136/bmj.f7393.
Miller C S CS Department of Oral Health Practice, Center for Oral Health Research, College of Dentistry, University of Kentucky, Lexington, KY, USA - - 2014
The comparative utility of serum and saliva as diagnostic fluids for identifying biomarkers of acute myocardial infarction (AMI) was investigated. The goal was to determine if salivary biomarkers could facilitate a screening diagnosis of AMI, especially in cases of non-ST elevation MI (NSTEMI), since these cases are not readily identified ...
Yoon So Jeong SJ Korea Artificial Organ Center, Korea University, Seoul 136-705, Republic of Korea; Department of Biomedical Engineering, Biomedical Science of Brain Korea 21, Medical College, Korea University, Seoul 136-705, Republic of - - 2014
Hydrogel has been used for regenerating myocardial infraction (MI) as a delivery vehicle for cells and growth factors. This study showed that injectable hyaluronic acid (HA)-based hydrogels alone would effectively regenerate the damaged infarcted heart tissue. We found that there are two major factors of regeneration in MI. One is ...
Zhang Baowei B Department of cardiology, The Affiliated People's hospital of Jiangsu university, 8 Dianli road, Zhenjiang, Jiangsu 212002, - - 2014
Several clinical trials have shown inconsistent results regarding the effect of electrode positions on the success of electrical cardioversion. The aim of this meta-analysis was to investigate the effect of the anterior-posterior electrode position on the success of electrical cardioversion in patients undergoing external electrical cardioversion for atrial fibrillation. Pubmed, ...
Navarese Eliano Pio EP Department of Cardiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands; Department of Cardiology and Internal Medicine, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus Univeristy, Bydgoszcz, Poland; Systematic Investigation and Research on Interventions and Outcomes (SIRIO) MEDICINE Research Network. Electronic address: - - 2014
Patients with acute coronary syndromes (ACSs) still experience high rates of recurrent coronary events, particularly, early in their presentation. Statins yield substantial cardiovascular benefits, but the optimal timing of their administration, before or after percutaneous coronary intervention (PCI), remains unclear. We aimed to perform a meta-analysis of randomized controlled trials ...
Cameli Matteo M aCardiologia Universitaria, Università degli Studi di Siena, Siena bDipartimento di Emergenza e Trapianto Organi, Università degli Studi di Bari, Bari cAzienda Sanitaria Locale di Brindisi, Brindisi dDipartimento di Medicina Clinica e Sperimentale, Università degli Studi di Firenze, Firenze eDipartimento di Scienze Cliniche e Sperimentali, Università degli Studi di Brescia, Brescia fDipartimento di Medicina Interna e Malattie Cardiovascolari, Università degli Studi di Palermo, Palermo gDipartimento di Medicina Clinica e Sperimentale, Università degli Studi di Sassari, Sassari hDipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica, Università di Pisa, Pisa, - - 2014
Speckle tracking echocardiography (STE) is an imaging technique applied to the analysis of left atrial function. STE provides a non-Doppler, angle-independent and objective quantification of left atrial myocardial deformation. Data regarding feasibility, accuracy and clinical applications of left atrial strain are rapidly gathering. This review describes the fundamental concepts of ...
Komócsi András A Heart Institute, University of Pécs, - - 2014
Superior outcomes with transradial (TRPCI) versus transfemoral coronary intervention (TFPCI) in the setting of acute ST-segment elevation myocardial infarction (STEMI) have been suggested by earlier studies. However, this effect was not evident in randomized controlled trials (RCTs), suggesting a possible allocation bias in observational studies. Since important studies with heterogeneous ...
Zarinabad Niloufar - - 2014
First-pass perfusion cardiac magnetic resonance (CMR) allows the quantitative assessment of myocardial blood flow (MBF). However flow estimates are sensitive to the delay between the arterial and myocardial tissue tracer arrival time (tOnset) and the accurate estimation of MBF relies on the precise identification of tOnset. The aim of this ...
Wei Jingkai J Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, - - 2014
Mental stress-induced myocardial ischemia (MSIMI) has been associated with adverse prognosis in patients with coronary artery disease (CAD), but whether this is a uniform finding across different studies has not been described. We conducted a systematic review and meta-analysis of prospective studies examining the association between MSIMI and adverse outcome ...
Nakano Masataka - - 2014
We interrogated our autopsy registry to investigate the histopathologic features of early stent thrombosis (ST) in patients presenting with acute coronary syndrome (ACS). The occurrence of early ST following percutaneous coronary intervention (PCI) for ACS remains a clinical problem despite advances in stent technology in both bare metal and drug-eluting ...
Gao Hong-Hua HH Department of Neurology, The Fourth Affiliated Hospital of China Medical University , Shenyang, People's Republic of China - - 2014
This meta-analysis was performed to evaluate the relationships between the monocyte chemoattractant protein-1 (MCP-1) -2518A>G (rs1024611 A>G) polymorphism and its serum levels, and the risk of cerebral infarction. The PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library, and CBM databases were searched for relevant articles published before ...
Cao Yanjun Y School of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. - - 2014
Guanxin Shutong capsule (GXSTC) is a Chinese medicinal formula that has been used clinically for the treatment of chest pain, depression, palpitation and cardiovascular diseases in China for almost 10 years. The aim of the present study was to investigate the protective mechanisms against oxidative stress and apoptosis that GXSTC ...
Amit Guy G Biological Signal Processing Ltd, Tel-Aviv, - - 2014
Over four decades of high frequency electrocardiography research have provided a body of knowledge about QRS changes during myocardial ischemia, and the techniques to measure and quantify them. High-frequency QRS (HFQRS) components, being closely related to the pattern of ventricular depolarization, carry valuable clinical information. Changes in HFQRS amplitude and ...
Tao Qian Q Division of Image Processing (LKEB), Department of Radiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands, - - 2014
The aim of this study is to introduce and evaluate an approach for objective and reproducible scar identification from late gadolinium enhanced (LGE) MR by analysis of LGE data with post-contrast T1 mapping from a routinely acquired T1 scout Look-Locker (LL) sequence. In 90 post-infarction patients, a LL sequence was ...
Fragasso Gabriele G Clinical Cardiology, Heart Failure Unit, Istituto Scientifico San Raffaele, Milano, Italy. Electronic address: - - 2014
The prognostic utility of myocardial perfusion scintigraphy (MPS) in patients with angiographically normal coronary arteries has not been evaluated yet. Our aim was to determine the prognostic role of positive MPS in patients with angina, positive exercise test and smooth coronary arteries (syndrome X). A total of 156 patients with ...
Lee Won Woo WW Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam 463-707, Korea. ; Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul 110-744, - - 2014
The aim of this study was to investigate the most robust predictor of myocardial viability among stress/rest reversibility (coronary flow reserve [CFR] impairment), (201)Tl perfusion status at rest, (201)Tl 24 hours redistribution and systolic wall thickening of (99m)Tc-methoxyisobutylisonitrile using a dual isotope gated myocardial perfusion single-photon emission computed tomography (SPECT) ...
Hung Guang-Uei GU Chang Bing Show Chwan Memorial Hospital, Changhua, - - 2014
The use of SPECT phase analysis to optimize left-ventricular (LV) lead positions for cardiac resynchronization therapy (CRT) was performed at baseline, but CRT works as simultaneous right ventricular (RV) and LV pacing. The aim of this study was to assess the impact of RV apical (RVA) pacing on optimal LV ...
Yoshida Naoki N Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, - - 2014
Although several ECG criteria have been proposed for differentiating between left and right origins of idiopathic ventricular arrhythmias originating from the outflow tract (OT-VA), their accuracy and usefulness remain limited. This study was undertaken to develop a more accurate and useful ECG criterion for differentiating between left and right OT-VA ...
Aykan Ahmet Cağrı AC Clinic of Cardiology, Ahi Evren Chest Cardiovascular Surgery Education and Research Hospital; Trabzon-Turkey. - - 2014
The relationship between silent neuronal injury (SNI) and arterial stiffness assessed by cardio-ankle vascular index (CAVI) has not been evaluated in patients treated with coronary angiography and intervention due to acute coronary syndrome (ACS). The aim of this study is to evaluate the value of CAVI in prediction of SNI ...
Ahn Jung-Min JM Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
There are conflicting data regarding the benefit of intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) over angiography-guided PCI. Since the last meta-analysis was published, several new studies have been reported. We performed a comprehensive meta-analysis to evaluate the clinical impact of IVUS-guided PCI with drug-eluting stent compared with conventional angiography-guided ...
Piras Paolo P Dipartimento di Scienze, Università Roma Tre, Roma, Italy ; Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza-Università di Roma, Roma, Italy ; Center for Evolutionary Ecology, Roma, - - 2014
The aim of this study is to investigate human left ventricular heart morphological changes in time among 17 healthy subjects. Preliminarily, 2 patients with volumetric overload due to aortic insufficiency were added to our analyses. We propose a special strategy to compare the shape, orientation and size of cardiac cycle's ...
Wu Lina - - 2014
Left ventricular segmental wall motion analysis is important for clinical decision making in cardiac diseases. Strain analysis with myocardial tissue tagging is the non-invasive gold standard for quantitative assessment, however, it is time-consuming. Cardiovascular magnetic resonance myocardial feature-tracking (CMR-FT) can rapidly perform strain analysis, because it can be employed with ...
Du Zhiyong Z Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China ; Key Laboratory For Organ Failure Research, Ministry of Education of the People's Republic of China, Guangzhou, - - 2014
Elevated myocardial energy expenditure (MEE) is related with reduced left ventricular ejection fraction, and has also been documented as an independent predictor of cardiovascular mortality. However, the serum small-molecule metabolite profiles and pathophysiological mechanisms of elevated MEE in heart failure (HF) are still lacking. Herein, we used 1H-NMR-based metabolomics analysis ...
Chen Lihua L Department of Radiology, Taihu Hospital, Wuxi, Jiangsu Province, - - 2014
To use direct comparative studies or randomised controlled trials to compare the accuracy of cardiac magnetic resonance (CMR) and single-photon emission computed tomography (SPECT) for the detection of obstructive coronary artery disease (CAD). Various databases were searched for original articles published prior to June 2013. Studies were selected that performed ...
Wang Qi Q Department of Cardiology, the Fourth Affiliated Hospital of China Medical University, Shenyang, P.R. - - 2014
This meta-analysis aims to evaluate the relationships between seven functional polymorphisms in the CETP gene and myocardial infarction (MI) risk. The PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library, and CBM databases were searched for relevant articles published before March 1st, 2013 without any language restrictions. Meta-analysis ...
Turunen Mikko P MP Department of Biotechnology and Molecular Medicine, A.I.Virtanen Institute, University of Eastern Finland, Kuopio, - - 2014
"Epigenetherapy" alters epigenetic status of the targeted chromatin and modifies expression of the endogenous therapeutic gene. In this study we used lentiviral in vivo delivery of small hairpin RNA (shRNA) into hearts in a murine infarction model. shRNA complementary to the promoter of vascular endothelial growth factor (VEGF-A) was able ...
Hiremath Pranoti P Harvard Medical School, Boston, Massachusetts, United States of - - 2014
The transition from healthy myocardium to hypertensive heart disease is characterized by a series of poorly understood changes in myocardial tissue microstructure. Incremental alterations in the orientation and integrity of myocardial fibers can be assessed using advanced ultrasonic image analysis. We used a modified algorithm to investigate left ventricular myocardial ...
Kosmala Wojciech W Department of Cardiology, Wroclaw Medical University, Wroclaw, - - 2013
The contribution of postimplant optimization of device settings to the beneficial effect of cardiac resynchronization therapy (CRT) in heart failure is uncertain. We performed a meta-analysis to investigate the impact of CRT optimization on the improvement of left ventricular function, exercise capacity, and quality of life. We undertook a systemic ...
Sara Cimino C Department of Cardiology, "Sapienza" University, Rome, - - 2013
Thrombectomy during primary percutaneous coronary intervention (Th-PCI) improves myocardial reperfusion in the absence of significant changes, in the acute phase, in traditional two-dimensional (2D) echo indexes of left ventricular (LV) function. The aim of this study was to evaluate the potential of 2D speckle tracking echocardiography (2DSTE) analysis in assessing ...
Altiok Ertunc E Department of Cardiology, Pneumology, Angiology and Intensive Care, University Hospital RWTH Aachen, Aachen, - - 2013
Myocardial deformation analysis by speckle-tracking echocardiography (STE) has been shown to accurately predict viability in patients with chronic ischemic left ventricular (LV) dysfunction. The aim of this study was to evaluate two-dimensional STE for the prediction of global and segmental LV functional changes after acute myocardial infarction (AMI) in comparison ...
Kirisli Hortense A HA Department of Medical Informatics, Biomedical Imaging Group Rotterdam, Erasmus Medical Center, Rotterdam, The - - 2013
CT angiography (CTA) and SPECT myocardial perfusion imaging (MPI) are complementary imaging techniques to assess coronary artery disease (CAD). Spatial integration and combined visualization of SPECT MPI and CTA data may facilitate correlation of myocardial perfusion defects and subtending coronary arteries and thus offer additional diagnostic value over either stand-alone ...
Gimelli Alessia - - 2013
To evaluate the relationships among myocardial sympathetic innervation, perfusion and mechanical synchronicity assessed with cardiac cadmium-zinc-telluride (CZT) scintigraphy. A group of 29 patients underwent an evaluation of myocardial perfusion with (99m)Tc-tetrofosmin CZT scintigraphy and adrenergic innervation with (123)I-metaiodobenzylguanidine (MIBG) CZT scintigraphy. The summed rest score (SRS), motion score (SMS) and ...
Cuspidi Cesare - - 2013
AIM:: Left-ventricular hypertrophy (LVH) is a frequent complication in obese individuals; an updated review and meta-analysis focusing on this issue is lacking. Thus, we analysed the literature in order to provide a comprehensive information on the left-ventricular structural changes, as assessed by echocardiography, associated to obesity. A literature search using ...
Shacham Yacov Y Department of Cardiology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel. - - 2013
Studies on trials conducted before the use of thrombolysis demonstrated both short- and long-term benefits of beta-blockers, and one meta-analysis of those trials showed a 25% reduction in 1 year mortality. Treatment with beta-blockers was and continues to be recommended for patients after ST elevation myocardial infarction (STEMI), but many ...
Esteves Fabio P - - 2013
We set out to develop normal databases and prospectively validate abnormality criteria for a low-dose Tc-99m tetrofosmin myocardial perfusion SPECT protocol using the 530c CZT camera. All patients received 6 mCi rest/20 mCi stress doses of Tc-99m tetrofosmin. Rest and stress images were obtained over 7-9 and 5-7 minutes according to the chest ...
Woie Leik - - 2013
Current methods for the estimation of infarct size by late-enhanced cardiac magnetic imaging are based upon 2D analysis that first determines the size of the infarction in each slice, and thereafter adds the infarct sizes from each slice to generate a volume. We present a novel, automatic 3D method that ...
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