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Sacher Frederic F Hôpital Cardiologique du Haut-Lévêque, LIRYC Institute, Bordeaux University, INSERM, 1045, - - 2014
Catheter ablation of ventricular tachycardia (VT) is proven effective therapy particularly in patients with frequent defibrillator shocks. However, the optimal endpoint for VT ablation has been debated and additional endpoints have been proposed. At the same time, ablation strategies aiming at homogenizing the substrate of scar related VT have been ...
Liu Baoxin B Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. - - 2014
Terfenadine is a second generation histamine receptor antagonist which is widely used as a non‑sedating antihistamine to relieve allergic responses. However, terfenadine has been associated with a number of side effects on cardiac electrical activities through blocking multiple ion channels in the heart, particularly K+ channels. Previous studies have also ...
Hanneman Kate K *Department of Medical Imaging †Division of Cardiology, Peter Munk Cardiac Center, University Health Network, University of Toronto, Toronto, ON, - - 2014
The purpose of this study was to determine the prognostic significance of cardiac magnetic resonance imaging (MRI) findings in patients with apical hypertrophic cardiomyopathy (HCM). Cardiac MRI studies of 93 consecutive patients with apical HCM were retrospectively evaluated. Quantification of late gadolinium enhancement (LGE) was determined and expressed as a ...
Zhao Linshuang L Department of Endocrinology, Guangzhou Command Wuhan General Hospital, Wuhan, PR - - 2014
Objectives: To explore the relationship between the autoantibodies against the β1 and AT1 receptors and left ventricular dilatation in patients with type 2 diabetes (T2DM). Methods: The autoantibodies against the β1 and angiotensin II type 1 (AT1) receptors of T2DM patients with and without hypertension were screened by ELISA. Multiple ...
Hadid Claudio C Arrhythmias and Electrophysiology Section. Cardiology Service. Hospital Cosme Argerich. Buenos Aires, Argentina.. - - 2014
Ventricular arrhythmias are responsible for the majority of sudden cardiac deaths, particularly in patients with structural heart disease. Coronary artery disease, essentially previous myocardial infarction, is the most common heart disease upon which sustained ventricular tachycardia (VT) occurs, being reentry the predominant mechanism. Idiopathic dilated cardiomyopathy and Chagas disease are ...
Ruwald Martin H MH University of Rochester Medical Center, Rochester, NY & Gentofte Hospital, Hellerup, Denmark - - 2014
-Appropriate guideline criteria for use of ICDs do not take into account potential recovery of left ventricular ejection fraction (LVEF) in patients treated with CRT-D. -Patients randomized to CRT-D from the MADIT-CRT trial, who survived and had paired echocardiograms at enrollment and at 12-months (n=752) were included. Patients were evaluated ...
Suwatcharangkoon Sureerat S From the Department of Neurology, Wake Forest University Baptist Medical Center, Winston-Salem; Division of Neurology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, - - 2014
A 27-year-old human immunodeficiency virus-positive man presented with abdominal pain. Computed tomography of the abdomen revealed large right pleural effusion, pericardial effusion and marked ascites with diffuse intra- and extraperitoneal lymphadenopathy. Echocardiography showed severely reduced left ventricular systolic function. After drainage of pleural and pericardial fluid, the patient developed severe ...
Watanabe Eri E Section of Noninvasive Cardiovascular Imaging, Brigham and Women's Hospital and Harvard Medical School, Boston, - - 2014
-Strategies for prevention of sudden cardiac death (SCD) focus on severe left ventricular (LV) dysfunction, though most SCD post-myocardial infarction occurs in patients with mild/moderate LV dysfunction. We tested the hypothesis that infarct heterogeneity by cardiac magnetic resonance (CMR) is associated with mortality beyond left ventricular ejection fraction (LVEF) in ...
Peters Carli C Department of Medical Physics, University of Wisconsin, Madison, WI, - - 2014
Congenital ventricular wall defects are very rare and include congenital ventricular aneurysms (CVAs) and diverticula (CVDs). We report a series of five fetuses: three with CVAs and two with CVDs referred due to fetal arrhythmia. In addition to routine fetal echocardiography, fetal magnetocardiography (fMCG) was used. The literature in CVA ...
Campos Bieito B Electrophysiology Section, Department of Cardiology, Hospital Universitari Arnau de Vilanova, Lleida, - - 2014
Substrate ablation is commonly performed in patients with post-infarction cardiomyopathy and ventricular tachycardia (VT). Recognition of fragmented and late potentials during sinus rhythm is a tedious process subject to operator fatigue. The purpose of this study was to assess the value of automated analysis to quantify electrogram fragmentation and to ...
Rose-Jones Lisa J LJ Advanced Heart Failure & Pulmonary Hypertension, UNC Heart & Vascular Center, 6th Floor, Burnett-Womack Building, 160 Dental Circle, CB#7075, Chapel Hill, NC 27599, USA. Electronic address: - - 2014
Atrial fibrillation (AF) is exceedingly common in patients with heart failure (HF), as they share common risk factors. Rate control is the cornerstone of treatment for AF; however, restoration of sinus rhythm should be considered when more than minimal symptoms are present. Life-threatening ventricular arrhythmias are responsible for the primary ...
Shimahara Yusuke Y Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan - - 2014
Ventricular tachycardia (VT) associated with midventricular hypertrophic cardiomyopathy and apical aneurysm is rare, but is frequently refractory to medical therapy. We report a case of a 44-year old man with incessant VT despite undergoing catheter ablation in the neck of a left ventricular apical aneurysm. Resection of a hypertrophied midventricular ...
Cheng Alan A Johns Hopkins Medical Institutions, Baltimore, MD - - 2014
-Primary prevention implantable cardioverter defibrillators (ICDs) reduce all-cause mortality but the benefits are heterogeneous. Current risk stratification based on left ventricular ejection fraction has limited discrimination power. We hypothesize that biomarkers for inflammation, neurohumoral activation and cardiac injury can predict appropriate shocks and all-cause mortality in patients with primary prevention ...
Riess Matthias L ML Staff Anaesthesiologist, TVHS VA Medical Center, and Professor, Department of Anesthesiology, Vanderbilt University, Nashville, TN. Electronic address: - - 2014
Background: Anaesthetic postconditioning (APoC) attenuates myocardial injury following coronary ischaemia/reperfusion. We hypothesised that APoC at the initiation of cardiopulmonary resuscitation (CPR) will improve post resuscitation myocardial function along with improved mitochondrial function in a pig model of prolonged untreated ventricular fibrillation. Methods: In 32 pigs isoflurane anaesthesia was discontinued prior ...
Murray Scott W SW Institute for Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, UK; Department of Critical Care Research, University of Liverpool, Liverpool, UK. Electronic address: - - 2014
The investigation of asymptomatic but potentially vulnerable atherosclerosis is not yet a major focus for clinical Cardiologists. We have illustrated the contemporary investigation and treatment of such disease using a clinical case that involved monozygotic twins. One twin (T1) had unfortunately suffered a cardiac arrest whilst jogging and survived only ...
Wang Wei W Department of Emergency Medicine, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, - - 2014
Ventricular fibrillation (VF) is one of the most serious complications of acute myocardial infarction, with a high mortality rate. There is a lack of value of rescue thrombolysis in ST-segment elevation myocardial infarction (STEMI) complicated by VF. To examine the relationship between risk factors and mortality, and assess the value ...
Pezawas Thomas T Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria - - 2014
-Prophylactic defibrillator implantation is recommended in dilated, non-ischemic heart disease and left ventricular ejection fraction (LVEF) of 0·30-0·35 or less. Non-invasive testing should improve accuracy in decision-making of prophylactic defibrillator implantation. -We enrolled 60 patients (median age 57 years) with dilated cardiomyopathy and LVEF ≤0·50, and 30 control subjects (median ...
Chen Lin Y LY Cardiovascular Division, Department of Medicine, University of Minnesota Medical - - 2014
Evidence is emerging to indicate that atrial fibrillation (AF) is independently associated with an increased risk of sudden cardiac death (SCD). This association has been consistently observed in specific patient subgroups such as patients with myocardial infarction (MI), heart failure, and hypertension, and importantly, in the general population. Data from ...
Tschabrunn Cory M CM Cory M Tschabrunn, Harvard-Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, United - - 2014
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is primarily believed to be an inherited cardiomyopathy that subsequently results in significant myocardial fibrosis. The arrhythmogenic consequences that result from the development of fibrosis are similar to other nonischemic cardiomyopathies, but the unique endocardial-epicardial disease process of ARVC/D requires a specialized approach for arrhythmia ...
Kolb Christof C Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Faculty of Medicine, Technische Universität München, Munich, Germany. Electronic address: - - 2014
The OPTION (Optimal Anti-Tachycardia Therapy in Implantable Cardioverter-Defibrillator Patients Without Pacing Indications) trial sought to compare long-term rates of inappropriate shocks, mortality, and morbidity between dual-chamber and single-chamber settings in implantable cardioverter-defibrillators (ICDs) patients. The use of dual-chamber ICDs potentially allows better discrimination of supraventricular arrhythmias and thereby reduces inappropriate ...
Raghuram Akhil A Oregon Health & Science University, Portland - - 2014
Obstructive sleep apnea (OSA) is an independent risk factor for sudden cardiac death. The aim of this review was to study the relationship between OSA and ventricular arrhythmias. PubMed, Medline, and Cochrane databases were searched with MESH headings to find studies linking OSA and ventricular arrhythmias including ventricular ectopy, ventricular ...
An Zhe Z Department of Cardiology, China-Japan United Hospital of Jilin University, Changchun, - - 2014
In patients with acromegaly, cardiovascular complications are the main cause of death; sudden death has been associated with ventricular tachyarrhythmias. In other patients with life-threatening malignant ventricular tachyarrhythmias, surgical placement of an implantable cardioverter-defibrillator (ICD) has proved highly effective in reducing sudden death rates. The present article reports the case ...
Bardai Abdennasser A Heart Center, Departments of Cardiology and General Practice, Academic Medical Center & University of Amsterdam, Amsterdam, The Netherlands - - 2014
-Atrial Fibrillation (AF) is associated with sudden cardiac death (SCD). We aimed to study whether AF is associated with ventricular fibrillation (VF), the most common cause of SCD, and whether this association is independent of confounders, i.e., concomitant disease, use of antiarrhythmic or QT-prolonging drugs, and acute myocardial infarction (AMI). ...
Mgbako Ofole U OU Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Social Media and Health Innovation Lab, Penn Medicine Center for Health Care Innovation, Philadelphia, PA, - - 2014
To characterise defibrillation and cardiac arrest survival outcomes in movies. Movies from 2003-2012 with defibrillation scenes were reviewed for patient and rescuer characteristics, scene characteristics, defibrillation characteristics, additional interventions, and cardiac arrest survival outcomes. Resuscitation actions were compared with chain of survival actions and the American Heart Association (AHA) Emergency ...
Khazanie Prateeti P Duke Clinical Research Institute, Durham, NC; Duke University School of Medicine, Department of Medicine, Durham, - - 2014
-Cardiac resynchronization therapy with defibrillator (CRT-D) reduces morbidity and mortality among selected patients with heart failure in clinical trials. The effectiveness of this therapy in clinical practice has not been well studied. -We compared a cohort of 4471 patients from the National Cardiovascular Data Registry's ICD Registry™ hospitalized primarily for ...
Nogami Akihiko A From the Cardiovascular Division, University of Tsukuba, Tsukuba, Ibaraki, - - 2014
Mapping and Ablating the Trigger of Ventricular Fibrillation. Ventricular fibrillation (VF) is a malignant arrhythmia, usually initiated by a ventricular premature contraction (VPC) during the vulnerable period of cardiac repolarization. Ablation therapy for VF has been described and increasingly reported. Targets for VF triggers are VPC preceded Purkinje potentials or ...
Iizuka Takashi T From the Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, - - 2014
A 17-year-old man was urgently admitted to our hospital after successful external defibrillation of a first episode of ventricular fibrillation (VF), which developed during light exercise. He had no personal medical history, and no history of sudden death or syncope among close relatives. A 12-lead electrocardiogram recorded during sinus rhythm ...
Ruwald Martin H MH Heart Research Follow-up Program, University of Rochester Medical Center, Rochester, New York; Department of Cardiology, Gentofte Hospital, Hellerup, Denmark. Electronic address: - - 2014
A high percentage of biventricular pacing is required for optimal outcome in patients treated with cardiac resynchronization therapy (CRT), but the influence of ectopic beats on the success of biventricular pacing has not been well established. This study sought to determine if increased ectopic beats reduce the chance of high ...
Bogossian Harilaos H Märkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Germany; Department of Cardiology, University Witten/ Herdecke, Witten, - - 2014
The main tool for the differentiation of supraventricular tachycardia is the 12-lead electrocardiogram (ECG). Especially differentiating the atrioventricular nodal reentrant tachycardia (AVNRT) from the atrioventricular reentrant tachycardia (AVRT) due to concealed accessory pathway or from an atrial tachycardia (AT) is very important for catheter setting and ablation approach in an ...
Barbosa Marcia M MM Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Ecocenter, Socor Hospital, Belo Horizonte, Brazil. Electronic address: - - 2014
Sickle cell disease (SCD) is a hemoglobinopathy that is common worldwide. It usually presents with cardiac involvement, although data on systolic function are somewhat controversial. The aim of this study was to investigate the value of speckle-tracking strain, a deformation index, in detecting ventricular dysfunction in SCD. Ninety adult patients ...
Liu Enzhao E Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300211, People's Republic of - - 2014
Discrete potentials (DPs) have been recorded and targeted as the site of ablation of the outflow tract arrhythmias. The aim of the present study was to investigate the significance of DPs with respect to mapping and ablation for idiopathic outflow tract premature ventricular contractions (PVCs) or ventricular tachycardias (VTs). Seventeen ...
Kaye Gerald C GC University of Queensland, Brisbane, Queensland, Australia 4102. Electronic address: - - 2014
Implantable cardioverter defibrillator (ICD) leads have traditionally been placed at the right ventricular apex (RVA). An important minority of patients with an ICD may develop a future requirement for bradycardia support. Pacing from the RVA may be detrimental, promoting heart failure and mortality. Increasingly non-apical right ventricular (RVNA) lead positions ...
Szymanski Filip M FM - - 2014
Shock is a manifestation of circulatory failure related to an inadequate supply of oxygenated blood to the tissues. One type of shock is cardiogenic shock resulting from abnormalities of myocardial structure and function, impairment of mechanical function of the heart, or arrhythmia. Most commonly, cardiogenic shock is due to an ...
Pimentel Maurício M Curso de Pós-graduação em Ciências Cardiovasculares, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, - - 2014
Despite significant therapeutic advancements, heart failure remains a highly prevalent clinical condition associated with significant morbidity and mortality. In 30%-40% patients, the etiology of heart failure is nonischemic. The implantable cardioverter-defibrillator (ICD) is capable of preventing sudden death and decreasing total mortality in patients with nonischemic heart failure. However, a ...
Bilchick Kenneth C KC Department of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, - - 2014
Several clinical trials have established that cardiac resynchronization therapy in combination with an implantable cardioverter-defibrillator improves survival and alleviates heart failure symptoms in appropriately selected patients. Recent guidelines have expanded the indications to include patients with less severe heart failure. The aim of this study was to examine the extent ...
Kapel Gijsbert F L GF Department of Cardiology & Cardiac Surgery, Leiden University Medical Centre, Leiden, the - - 2014
-Radiofrequency catheter ablation (RFCA) of ventricular tachycardia (VT) in repaired Tetralogy of Fallot (rTOF) focuses on isthmuses in the right ventricle but may be hampered by hypertrophied myocardium or prosthetic material. These patients may benefit from ablation at the left side of the ventricular septum. -Records from 28 consecutive rTOF ...
Kuga Keisuke K Department of Cardiology, Faculty of Medicine, University of - - 2014
Background:Indications of implantable cardioverter-defibrillator (ICD) for patients with an old myocardial infarction (OMI) and left ventricular dysfunction (LVD) were expanded in Western countries after the results of MADIT II. However, the prognosis of OMI patients with LVD and the merits of prophylactic implantation of ICD, based on evidence in Japan, ...
Babaeizadeh Saeed S Advanced Algorithm Research Center, Philips Healthcare, Andover, MA. Electronic address: - - 2014
Defibrillation is often required to terminate a ventricular fibrillation or fast ventricular tachycardia rhythm and resume a perfusing rhythm in sudden cardiac arrest patients. Automated external defibrillators rely on automatic ECG analysis algorithms to detect the presence of shockable rhythms before advising the rescuer to deliver a shock. For a ...
Colquitt Jill L JL , - - 2014
This assessment updates and expands on two previous technology assessments that evaluated implantable cardioverter defibrillators (ICDs) for arrhythmias and cardiac resynchronisation therapy (CRT) for heart failure (HF). To assess the clinical effectiveness and cost-effectiveness of ICDs in addition to optimal pharmacological therapy (OPT) for people at increased risk of sudden ...
Viana Marcelo A MA Department of Biomedical Engineering, School of Electrical and Computer Engineering, University of Campinas (UNICAMP), Campinas, São Paulo, - - 2014
Cardiac arrest after open surgery has an incidence of approximately 3%, of which more than 50% of the cases are due to ventricular fibrillation. Electrical defibrillation is the most effective therapy for terminating cardiac arrhythmias associated with unstable hemodynamics. The excitation threshold of myocardial microstructures is lower when external electrical ...
Te Riele Anneline - - 2014
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is one of the most arrhythmogenic forms of inherited cardiomyopathy and a frequent cause of sudden death in the young. Affected individuals typically present between the second and fourth decade of life with arrhythmias coming from the right ventricle. Pathogenic mutations in genes encoding the ...
Ward Alexandra E AE Department of Medicine, University of Maryland School of Medicine, Baltimore, - - 2014
We describe a 45-year old man who experienced a potentially fatal arrhythmia after consumption of multiple energy drinks. At 5 years old, he underwent "repair" of tetralogy of Fallot using a patch in the right ventricular outflow tract, and at age 40 had an automatic implantable cardiac defibrillator (AICD) placed. ...
Alp Hayrullah H Pediatric Cardiology Clinic, Malatya State Hospital, Malatya, - - 2014
Isolated right ventricular hypertrophy (RVH) is a rare form of hypertrophic cardiomyopathy and premature closure of the patent ductus arteriosus in utero is a probable etiologic factor. We reported transient isolated RVH in three neonates and ventricular hypertrophy resolved within 8-10 weeks period without any specific therapy in all cases.
Wase Abdul A Clinical Professor of Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH, USA; Director, Electrophysiology Laboratories, Dayton Heart and Vascular Hospital at Good Samaritan Hospital, Dayton, OH, - - 2014
Bidirectional ventricular tachycardia (BVT) is a rare variety of tachycardia with morphologically distinct presentation: The QRS axis and/or morphology is alternating in the frontal plane leads. Since its original description in association with digitalis,(1) numerous cases of this fascinating tachycardia with disparate etiologies and mechanisms have been postulated. We report ...
Gibson C Michael CM Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA. Electronic address: - - 2014
In the setting of ST-segment elevation myocardial infarction, timely restoration of normal blood flow is associated with improved myocardial salvage and survival. Despite improvements in door-to-needle and door-to-balloon times, there remains an unmet need with respect to improved symptom-to-door times. A prior report of an implanted device to monitor ST-segment ...
Ahmadi Alireza A Assistant Professor, Department of Pediatrics AND Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, - - 2014
Tachycardia-induced cardiomyopathy (TIC) is a rare cause of dilated cardiomyopathy (DCMP). The diagnosis can be missed because tachycardia is a common symptom in DCMP. We reviewed a case 5-year-old with palpitation and dyspnea with symptoms and signs of heart failure that diagnosed as DCMP initially. Then, in the evaluation for ...
Kunisek Juraj J Thalassotherapia Crikvenica, Special Hospital for Medical Rehabilitation; Crikvenica-Croatia. - - 2014
To investigate the possible electrophysiological background of the greater excitability of concentric and eccentric left ventricular hypertrophy types in relation to the asymmetric type. 187 patients with essential hypertension, without ishaemic heart disease were divided into three groups with regard to left ventricule type: concentric (relative wall thickness >0.42, interventricular ...
Patil Kiran G - - 2014
We report an unusual case of a 22-year-old male who was incidentally diagnosed with isolated noncompaction of the left ventricle (LV) when he was admitted with viral myocarditis. Left ventricular noncompaction (LVNC) is a congenital cardiomyopathy which presents with ventricular dysfunction, cardioembolic manifestations or with arrhythmias. A diagnosis can be ...
Nageh Maged F MF Department of Electrophysiology, Kaiser Permanente Southern California, Los Angeles, CA - - 2014
Randomized studies of implantable cardioverter defibrillators (ICD) have excluded sudden cardiac death survivors who had revascularization before or after an arrhythmic event. To evaluate the role of ICD and the effects of clinical variables including degree of revascularization, we studied cardiac surgery patients who had an ICD implanted for sustained ...
Kondo Takeshi - - 2014
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is characterized by progressive fatty and fibrous replacement. A female in her 70s, suddenly found in cardiopulmonary arrest. The heart weighed 452 g and yellow discoloration was observed. Histological examination revealed the replacement of the right ventricular myocardium by adipose tissue and fibrosis. The cause ...
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