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McGovern Meghan M The Sarver Heart Center at the University of Arizona College of Medicine, Tucson, - - 2014
In retrospective swine and human investigations of ventricular fibrillation (VF) cardiac arrest, the amplitude-spectral area (AMSA), determined from the VF waveform, can predict defibrillation and a return of spontaneous circulation (ROSC). We hypothesized that an algorithm using AMSA in real time to direct postshock chest compression (CC) duration would shorten ...
Satake Hiroyuki H Department of Cardiovascular Medicine, Tohoku University Graduate School of - - 2014
Background:The current status of primary prevention of sudden cardiac death (SCD) with implantable cardioverter defibrillator (ICD) in patients with heart failure with reduced ejection fraction remains to be fully elucidated in Japan.Methods and Results:In the chronic heart failure (CHF) cohort study, the CHART-2 Study, we enrolled 2,778 consecutive patients with NYHA class ...
Asirvatham Samuel J SJ Division of Cardiovascular Diseases, Department of Medicine - Department of Pediatrics and Adolescent Medicine, Mayo Clinic, Rochester, - - 2014
In this issue of JCE, Professor Nogami(1) outlines a detailed approach to ablate what is among the most difficult of arrhythmias to treat - triggered ventricular fibrillation (VF). He provides us tips for mapping electrocardiographically and using the invasive electrograms to identify the culprit trigger, and also outlines a technique ...
Baztarrica Gabriel E GE Department of Cardiology and Physiology, Faculty of Medicine, Universidad Abierta Interamericana, Buenos Aires, Argentina. E-mail. - - 2014
Ebstein's anomaly (EA) is a rare congenital malformation, characterized by an apical displacement and dysplasia of the septal leaflet of the tricuspid valve with a right ventricular atrialization compromising its function. This malformation includes electrical conduction abnormalities, and very rarely ventricular arrhythmias. We report the case of a 22-year-old male, ...
Ruwald Martin H MH Heart Research Follow-up Program. University of Rochester Medical Center, Rochester, NY, US; Department of Cardiology, Gentofte Hospital, Hellerup, - - 2014
It is unknown whether circadian variation of ventricular tachyarrhythmias (VTA) affects clinical outcome in heart failure patients. A total of 1790 patients (males 75%) with heart failure, NYHA class I and II and implantable cardioverter defibrillators (ICD) or cardiac resynchronization (CRT-D) enrolled in the MADIT-CRT study were included. Time of ...
Gouda Sherif S Department of Cardiovascular Medicine, Cairo University, Cairo, - - 2014
Better risk-stratification tools are needed to identify the best candidates for implantable cardioverter defibrillator implantation. Infarct characterization by cardiac magnetic resonance (CMR) has become an evolving potential tool for risk stratification. We assessed the ability of scar characteristics by CMR in patients with postinfarction left ventricular (LV) dysfunction to predict ...
Chahal Anwar A AA Anwar A Chahal, Min-Young Kim, Alexander N Borg, Yahya Al-Najjar, Department of Cardiology, Blackpool Victoria Hospital, Blackpool FY3 8LP, United - - 2014
We report an unusual case of an isolated right ventricular infarction with haemodynamic compromise caused by spontaneous isolated proximal occlusion of the right ventricular branch of the right coronary artery (RCA), successfully treated by balloon angioplasty. A 58-year-old gentleman presented with epigastric pain radiating into both arms. Electrocardiograph with right ...
Bartczak Agnieszka A 1st Department of Cardiology, Poznan University of Medical Sciences, Poznań, - - 2014
Indications for sudden cardiac death (SCD) primary prevention are unknown in patients with repaired tetralogy of Fallot (ToF). The role of microvolt T-wave alternans (MTWA) in SCD risk stratification was documented. However, the prevalence of spectral MTWA and its association with ventricular arrhythmia (VA) in adults after ToF repair were ...
Kapel Gijsbert F L GF Department of Cardiology, Leiden University Medical Centre, Leiden, the - - 2014
-Ventricular tachycardia (VT) is an important cause of late morbidity and mortality in repaired congenital heart disease (rCHD). The substrate often includes anatomical isthmuses that can be transected by radiofrequency catheter ablation (RFCA) similar to isthmus block for atrial flutter. This study evaluates the long-term efficacy of isthmus block for ...
Sabate Rotes Anna A Division of Cardiovascular Disease, Mayo Clinic, Rochester, MN & Universitat Autònoma de Barcelona, Barcelona, - - 2014
-Most patients with repaired tetralogy of Fallot (TOF) require pulmonary valve replacement (PVR), but the evaluation for and management of ventricular arrhythmia remains unclear. This study is aimed at clarifying the optimal approach to this potentially life-threatening issue at the time of PVR. -A retrospective analysis was performed on 205 ...
Steinberg Mikkel T MT University of Oslo, Medical Student Research Program, University of Oslo, Oslo, Norway; Norwegian National Advisory Unit on Prehospital Emergency Medicine, Oslo University Hospital, Oslo, Norway. Electronic address: - - 2014
Guidelines recommend two minutes of CPR after defibrillation attempts followed by ECG analysis during chest compression pause. This pause may reduce the likelihood of return of spontaneous circulation (ROSC) and survival. We have evaluated the possibility of analysing the rhythm earlier in the CPR cycle in an attempt to replace ...
Gouda Sherif - - 2014
Idiopathic ventricular tachycardia (VT) and/or premature ventricular contractions (PVCs) arise most commonly from the right ventricular outflow tract and less frequently from the left ventricular outflow tract (LVOT), either below or above the semilunar valves. We report a case of 24-year-old man with idiopathic ventricular tachycardia from a single focus ...
Fujita Takashi T Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, - - 2014
Occurrence of malignant ventricular tachyarrhythmias such as ventricular tachycardia and fibrillation (VT/VF) in hypertrophic cardiomyopathy (HCM) can be related to the extent of myocardial fibrosis. Although late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging has been used to detect myocardial fibrosis, few data exist regarding relationships between CMR-determined ...
Maury Philippe P Department of Cardiology, University Hospital Rangueil, Toulouse, - - 2014
Outflow tract ventricular arrhythmias represent an important chapter in clinical electrophysiology. Recent investigations enhance the knowledge in that field and highlight new important concepts in ventricular arrhythmogenesis. Recent publications have revealed new interesting results in the field of outflow tract ventricular arrhythmias. The embryonic phenotype is maintained in the adult ...
Dembek Katarzyna A KA From the Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH - - 2014
To describe a case of supraventricular tachycardia and sudden death in a horse following administration of flecainide acetate. An 8-year-old Hanoverian warmblood gelding was treated for chronic, naturally occurring, supraventricular tachycardia with digoxin, procainamide hydrochloride, quinidine sulfate, and flecainide acetate. After oral administration of flecainide, polymorphic ventricular tachycardia (torsades de ...
Manolis Antonis S AS Athens University School of Medicine, Athens, - - 2014
Unfortunately, of all patients experiencing acute myocardial infarction (MI), usually in the form of ST-elevation MI, 25-35% will die of sudden cardiac death (SCD) before receiving medical attention, most often from ventricular fibrillation. For patients who reach the hospital, prognosis is considerably better and has improved over the years. Reperfusion ...
Kotake Yasuhito Y Division of Cardiology, Department of Medicine, Faculty of Medicine, Kinki University, Osaka, - - 2014
The most critical adverse effects of class III drugs are marked QT prolongation and torsade de pointes. Even though intravenous amiodarone (iv-Amio) is a representative class III drug, it peculiarly inhibits both clinical ventricular tachycardia/fibrillation (VT/VF) and proarrhythmic effects. To test the hypothesis that iv-Amio homogeneously prolongs repolarization, we evaluated ...
Doytchinova Anisiia A Krannert Institute of Cardiology and the Division of Cardiology, Department of Medicine, Indiana University School of - - 2014
Stellate ganglion nerve activity (SGNA) is important in ventricular arrhythmogenesis. However, because thoracotomy is needed to access the stellate ganglion, it is difficult to use SGNA for risk stratification. To test the hypothesis that subcutaneous nerve activity (SCNA) in canines can be used to estimate SGNA and predict ventricular arrhythmia. ...
Facchin Michela M Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, - - 2014
This case illustrates a ventricular fibrillation due to documented diffuse coronary vasospasm leading to necrotic and ischemic lesions, documented by cardiac magnetic resonance (CMR). This clinical report emphasizes the role of CMR to identify myocardial tissue abnormalities explaining that coronary vasospasm does not always have a benign prognosis, sometimes requiring ...
Draper Timothy S TS Jr Department of Cardiovascular Medicine, Lahey Hospital and Medical Center, Burlington MA; Tufts University School of Medicine, Boston, MA. Electronic address: - - 2014
The relation of life threatening ventricular arrhythmias to specific patterns of adverse LV remodeling has not been reported. We examined the relationship of ventricular tachycardia and/or fibrillation (VT/VF) to the pattern of left ventricular (LV) structural remodeling and to the degree of LV dysfunction in patients with a low ejection ...
Golian Mehrdad - - 2014
Extracorporeal membrane oxygenation (ECMO) technology is a viable option for short-term support in the setting of acute cardiac ischemia. To supplement cardiopulmonary resuscitation (CPR) in select patients, ECMO is used successfully for witnessed in hospital cardiac arrest. In the setting of an acute myocardial infarction (MI), bridging to a revascularization ...
Huang Bao-Tao BT Department of Cardiology, West China Hospital, Sichuan University, Chengdu, - - 2014
Although inappropriate left ventricular mass has been associated with clustered cardiac geometric and functional abnormalities, its predictive value in patients with coronary artery disease is still unknown. This study examined the association of inappropriate left ventricular mass with clinical outcomes in patients with angina pectoris and normal ejection fraction. Consecutive ...
Einbinder Tom T Department of Pediatric Cardiology, Schneider Children's Medical Center of Israel, Kaplan 14, Petach Tikva 49202, Israel - - 2014
This is a report of a child with Brugada syndrome who experienced ventricular fibrillation storm. Initial presentation was atrial fibrillation without the Brugada-type electrocardiogram, aborted cardiac arrest and positive family history of sudden death.
Davogustto Giovanni G Department of Internal Medicine. University of Texas Health Science Center at Houston. Houston, - - 2014
Soccer is the most popular sport in the world, with over 200 million active players. Sudden cardiac death (SCD) represents the most striking as well as the most common cause of death in the soccer field. Underlying cardiovascular pathologies predispose to life threatening ventricular arrhythmias and SCD in soccer players. ...
Sasaki Shingo S Department of Advanced Management of Cardiac Arrhythmias, Hirosaki University Graduate School of - - 2014
Background:Wearable cardioverter-defibrillators (WCD) have been available in Japan since April 2014, but their application is still limited.Methods and Results:We report 9 patients with a WCD applied between April and September 2014. All patients were at high risk of life-threatening ventricular arrhythmias. During WCD use, 1 patient had sustained ventricular tachycardia and successful ...
Crea Pasquale P Department of Clinical and Experimental Medicine and Unità di Terapia Cardiologica Intensiva e Interventistica, University Hospital of Messina. Electronic address: - - 2014
We report the case of a 56-year-old male with ischemic cardiomyopathy, severe left ventricular dysfunction and right bundle branch block (RBBB) with a wide QRS duration (180ms) who received dual-chamber implantable cardioverter-defibrillator for primary prevention of sudden death. After having placed the right ventricular lead in the middle of the ...
Bhimani Ashish A AA University of Texas Medical Branch, Galveston, - - 2014
A 35-year-old man with non-ischemic cardiomyopathy underwent a single chamber implantable cardioverter defibrillator (ICD) implant with a St. Jude Medical Fortify VR pulse generator and an active fixation ventricular lead (St. Jude Durata model 7121, 65 cm) for the primary prevention of sudden cardiac arrest. Twenty months after device implant, ...
Di Bella Gianluca G Institute of Clinical Physiology, CNR, Via Moruzzi, 1, 56124, Pisa, - - 2014
Prognostic implication of right ventricular dysfunction and infarction scar in the chronic phase of the myocardial infarction has been little analyzed. In 299 consecutive patients (age 63 ± 11 years) with >3 months old myocardial infarction, we quantified right and left ventricular volumes and ejection fractions by cine cardiac magnetic resonance, and right and ...
Tian Leiqi L Department of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. - - 2014
To evaluate the prenatal diagnosis of ventricular non-compaction cardiomyopathy (NCCM) and to report the pathologic features and the characteristic myocardial ultrastructure of fetal NCCM. We examined 9 cases of fetal NCCM by prenatal echocardiography from 2004 to 2013. These cases were evaluated with respect to prenatal diagnosis, outcomes, pathology and ...
Sacher Frederic F Hôpital Cardiologique du Haut-Lévêque, LIRYC Institute, Bordeaux University, INSERM, 1045, - - 2014
Catheter ablation of ventricular tachycardia (VT) is proven effective therapy particularly in patients with frequent defibrillator shocks. However, the optimal endpoint for VT ablation has been debated and additional endpoints have been proposed. At the same time, ablation strategies aiming at homogenizing the substrate of scar related VT have been ...
Bonnes Judith L JL Department of Cardiology, Radboud University Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address: - - 2014
Ventricular fibrillation (VF) waveform characteristics are associated with cardiac arrest duration and defibrillation success. Recent animal studies found that VF characteristics and shock success also depend on the presence of myocardial infarction (MI). In patients, VF induction after implantable cardioverter defibrillator (ICD) implantation offers a unique setting to study early ...
Filipe Mando D MD University of Groningen, University Medical Center Groningen, Department of Cardiology, The - - 2014
Heart failure (HF) is a leading cause of mortality in the western world. Despite advances in the treatment of HF, like the use of angiotensin-converting enzyme (ACE) inhibitors, β-blockers, angiotensin receptor blockers (ARBs), mineralocorticoid receptor antagonists (MRAs), and implantable cardiac defibrillators, prognosis of HF patients remains poor. For clinicians dealing ...
Raghuram Akhil A Oregon Health & Science University, Portland - - 2014
Obstructive sleep apnea (OSA) is an independent risk factor for sudden cardiac death. The aim of this review was to study the relationship between OSA and ventricular arrhythmias. PubMed, Medline, and Cochrane databases were searched with MESH headings to find studies linking OSA and ventricular arrhythmias including ventricular ectopy, ventricular ...
Liu Baoxin B Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. - - 2014
Terfenadine is a second generation histamine receptor antagonist which is widely used as a non‑sedating antihistamine to relieve allergic responses. However, terfenadine has been associated with a number of side effects on cardiac electrical activities through blocking multiple ion channels in the heart, particularly K+ channels. Previous studies have also ...
Hanneman Kate K *Department of Medical Imaging †Division of Cardiology, Peter Munk Cardiac Center, University Health Network, University of Toronto, Toronto, ON, - - 2014
The purpose of this study was to determine the prognostic significance of cardiac magnetic resonance imaging (MRI) findings in patients with apical hypertrophic cardiomyopathy (HCM). Cardiac MRI studies of 93 consecutive patients with apical HCM were retrospectively evaluated. Quantification of late gadolinium enhancement (LGE) was determined and expressed as a ...
Zhao Linshuang L Department of Endocrinology, Guangzhou Command Wuhan General Hospital, Wuhan, PR - - 2014
Objectives: To explore the relationship between the autoantibodies against the β1 and AT1 receptors and left ventricular dilatation in patients with type 2 diabetes (T2DM). Methods: The autoantibodies against the β1 and angiotensin II type 1 (AT1) receptors of T2DM patients with and without hypertension were screened by ELISA. Multiple ...
Hadid Claudio C Arrhythmias and Electrophysiology Section. Cardiology Service. Hospital Cosme Argerich. Buenos Aires, Argentina.. - - 2014
Ventricular arrhythmias are responsible for the majority of sudden cardiac deaths, particularly in patients with structural heart disease. Coronary artery disease, essentially previous myocardial infarction, is the most common heart disease upon which sustained ventricular tachycardia (VT) occurs, being reentry the predominant mechanism. Idiopathic dilated cardiomyopathy and Chagas disease are ...
Ruwald Martin H MH University of Rochester Medical Center, Rochester, NY & Gentofte Hospital, Hellerup, Denmark - - 2014
-Appropriate guideline criteria for use of ICDs do not take into account potential recovery of left ventricular ejection fraction (LVEF) in patients treated with CRT-D. -Patients randomized to CRT-D from the MADIT-CRT trial, who survived and had paired echocardiograms at enrollment and at 12-months (n=752) were included. Patients were evaluated ...
Sriram Chenni S CS Division of Electrophysiology, Heart & Vascular Institute, Penn State Milton S. Hershey Medical Center, Hershey, PA, United - - 2014
The authors report the unique case of remote onset of exercise induced focal ventricular tachycardia in a 40-year old male patient that originated from the ventricular end of an accessory atrioventricular pathway 18months after a successful ablation. There was no residual conduction across the pathway after the first ablation. The ...
Suwatcharangkoon Sureerat S From the Department of Neurology, Wake Forest University Baptist Medical Center, Winston-Salem; Division of Neurology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, - - 2014
A 27-year-old human immunodeficiency virus-positive man presented with abdominal pain. Computed tomography of the abdomen revealed large right pleural effusion, pericardial effusion and marked ascites with diffuse intra- and extraperitoneal lymphadenopathy. Echocardiography showed severely reduced left ventricular systolic function. After drainage of pleural and pericardial fluid, the patient developed severe ...
Watanabe Eri E Section of Noninvasive Cardiovascular Imaging, Brigham and Women's Hospital and Harvard Medical School, Boston, - - 2014
-Strategies for prevention of sudden cardiac death (SCD) focus on severe left ventricular (LV) dysfunction, though most SCD post-myocardial infarction occurs in patients with mild/moderate LV dysfunction. We tested the hypothesis that infarct heterogeneity by cardiac magnetic resonance (CMR) is associated with mortality beyond left ventricular ejection fraction (LVEF) in ...
Peters Carli C Department of Medical Physics, University of Wisconsin, Madison, WI, - - 2014
Congenital ventricular wall defects are very rare and include congenital ventricular aneurysms (CVAs) and diverticula (CVDs). We report a series of five fetuses: three with CVAs and two with CVDs referred due to fetal arrhythmia. In addition to routine fetal echocardiography, fetal magnetocardiography (fMCG) was used. The literature in CVA ...
Campos Bieito B Electrophysiology Section, Department of Cardiology, Hospital Universitari Arnau de Vilanova, Lleida, - - 2014
Substrate ablation is commonly performed in patients with post-infarction cardiomyopathy and ventricular tachycardia (VT). Recognition of fragmented and late potentials during sinus rhythm is a tedious process subject to operator fatigue. The purpose of this study was to assess the value of automated analysis to quantify electrogram fragmentation and to ...
Riess Matthias L ML TVHS VA Medical Center, Nashville, TN, United States; Department of Anesthesiology, Vanderbilt University, Nashville, TN, United States. Electronic address: - - 2014
Anaesthetic postconditioning (APoC) attenuates myocardial injury following coronary ischaemia/reperfusion. We hypothesised that APoC at the initiation of cardiopulmonary resuscitation (CPR) will improve post resuscitation myocardial function along with improved mitochondrial function in a pig model of prolonged untreated ventricular fibrillation. In 32 pigs isoflurane anaesthesia was discontinued prior to induction ...
Rose-Jones Lisa J LJ Advanced Heart Failure & Pulmonary Hypertension, UNC Heart & Vascular Center, 6th Floor, Burnett-Womack Building, 160 Dental Circle, CB#7075, Chapel Hill, NC 27599, USA. Electronic address: - - 2014
Atrial fibrillation (AF) is exceedingly common in patients with heart failure (HF), as they share common risk factors. Rate control is the cornerstone of treatment for AF; however, restoration of sinus rhythm should be considered when more than minimal symptoms are present. Life-threatening ventricular arrhythmias are responsible for the primary ...
Shimahara Yusuke Y Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan - - 2014
Ventricular tachycardia (VT) associated with midventricular hypertrophic cardiomyopathy and apical aneurysm is rare, but is frequently refractory to medical therapy. We report a case of a 44-year old man with incessant VT despite undergoing catheter ablation in the neck of a left ventricular apical aneurysm. Resection of a hypertrophied midventricular ...
Cheng Alan A Johns Hopkins Medical Institutions, Baltimore, MD - - 2014
-Primary prevention implantable cardioverter defibrillators (ICDs) reduce all-cause mortality but the benefits are heterogeneous. Current risk stratification based on left ventricular ejection fraction has limited discrimination power. We hypothesize that biomarkers for inflammation, neurohumoral activation and cardiac injury can predict appropriate shocks and all-cause mortality in patients with primary prevention ...
Yilmaz Mehmet M Department of Anesthesiology, Kocaeli Derince Education and Research Hospital, - - 2014
Ventricular fibrillation is common after aortic declamping in patients undergoing open heart surgery. This situation has a negative impact on morbidity and mortality. The aim of this prospective study was to compare the effect of administering lidocaine versus amiodarone before aortic declamping during elective coronary bypass grafting, paying close attention ...
Murray Scott W SW Institute for Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, UK; Department of Critical Care Research, University of Liverpool, Liverpool, UK. Electronic address: - - 2014
The investigation of asymptomatic but potentially vulnerable atherosclerosis is not yet a major focus for clinical Cardiologists. We have illustrated the contemporary investigation and treatment of such disease using a clinical case that involved monozygotic twins. One twin (T1) had unfortunately suffered a cardiac arrest whilst jogging and survived only ...
Wang Wei W Department of Emergency Medicine, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, - - 2014
Ventricular fibrillation (VF) is one of the most serious complications of acute myocardial infarction, with a high mortality rate. There is a lack of value of rescue thrombolysis in ST-segment elevation myocardial infarction (STEMI) complicated by VF. To examine the relationship between risk factors and mortality, and assess the value ...
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