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Results 451 - 500 of 549
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Laschinger J C - - 1987
Spinal cord injury following operations on the descending thoracic or thoracoabdominal aorta remains a major problem. In certain subsets of patients, the risk of postoperative spinal cord injury is substantial. Although several adjuncts have been employed clinically to eliminate or reduce the frequency of this complication, none have proven to ...
Zitsch R P - - 1987
The course of the left recurrent laryngeal nerve through the chest brings it in close proximity with the heart and great cardiac vessels. Diseases of the heart and the great vessels are known to cause vocal cord paralysis, probably by mechanical injury to the recurrent laryngeal nerve. Pulmonary artery hypertension ...
Sperry K L - - 1987
Myocardial infarction occurring during pregnancy or the puerperium is a rare condition, occurring in about 1 per 10,000 deliveries, and carries a mortality of approximately 30%. As a consequence of its rarity, symptoms of impending infarction may be easily mistaken by physicians for much more common and innocuous conditions, especially ...
Riker C D - - 1987
An unusual fatality involving a 26-year-old male who intentionally ingested approximately 10 g of metoprolol is presented. Autopsy findings revealed foreign material in the gastric content with an acute thrombosis of the left anterior descending coronary artery. Microscopic studies showed evidence of an extremely early infarct. Metoprolol concentrations in the ...
Goldenberg S P - - 1987
Cardiovascular complications from cocaine use have been recognized in increasing frequency in recent years. We report the case of a young man with a history of intranasal cocaine use presenting with acute congestive heart failure who, on postmortem examination, was found to have idiopathic hemochromatosis. It is speculated that cocaine ...
Doi K - - 1987
Spontaneous cardiac and renal lesions in APA hamsters were examined histopathologically. Myocardial degeneration, valvular thickening, coronary arterial degeneration and increase in heart weight were common in old hamsters. These changes, which suggest cardiac failure, seem to be related to cardiac thrombosis which predominantly affected the left atrium and was found ...
Wehbie C S - - 1987
We have described a young man who had acute myocardial infarction after his first use of cocaine. This case demonstrates that potentially lethal myocardial infarctions may be associated with such initial "experimentation" with cocaine even in relatively small doses. Cocaine intoxication should be considered in young patients with acute myocardial ...
Smith H W HW - - 1987
Ischemic chest pain syndromes and myocardial infarction occurred within minutes to hours of cocaine use in nine persons ages 23 to 39 years. Five developed symptoms after taking cocaine intranasally; three, after intravenous use; and one, after smoking cocaine. Four were habitual users and five were recreational users; eight also ...
Conti C R - - 1987
Potential causes for the development of acute myocardial ischemia include extracardiac factors, rapid progression of atherosclerosis, dynamic coronary artery thrombosis, platelet activation in diseased vessels, abnormal constriction of a coronary artery, and abnormal arachidonic acid metabolism. It is entirely possible that all or many of these potential causes may be ...
Eisenberg P R - - 1987
To assess whether the intense thrombotic state known to occur early after the onset of acute myocardial infarction is further exacerbated by impaired intrinsic fibrinolysis, we compared the intensity of fibrinolysis as measured by the level of crosslinked fibrin degradation products (XL-FDP) in plasma with the intensity of thrombosis as ...
Bowdler A J - - 1987
A 58-year-old man had anemia and thrombocytopenia immediately after a myocardial infarction; recovery occurred spontaneously, but relapses followed intercurrent infection and abdominal surgery. The terminal relapse was precipitated by gastric ulcer with hemorrhagic gastritis; this episode was characterized by fluctuating neurologic symptoms including coma. Autopsy studies confirmed the diagnosis of ...
Zimmerman F H - - 1987
Myocardial infarction is increasingly recognized as a complication of cocaine abuse. A significant number of persons suffering from myocardial infarction associated with cocaine abuse do not have significant coronary atherosclerosis, and the mechanism for infarction in these patients has remained obscure. This report describes a young man with angiographically normal ...
Tazelaar H D - - 1987
There is increasing evidence that cocaine can have serious adverse effects on the heart. Angina, myocardial infarction, coronary artery spasm, arrhythmia, and sudden death have been reported in association with its use. There have been only two reports of actual myocardial pathology. In an attempt to clarify the pathophysiology of ...
Saffitz J E - - 1987
Autopsy and clinical studies indicate that coronary thrombosis plays a key role in the development of acute transmural myocardial infarction and possibly in unstable angina and sudden cardiac death. The pathogenesis of coronary thrombosis is complex. It involves the dynamic interplay among the atherosclerotic arterial wall, vasomotor influences, cellular and ...
Guindi M M - - 1987
In cardiac procedures that use access to the right atrium, the coronary sinus is at risk of accidental trauma and subsequent thrombosis as demonstrated by the two cases reported in this paper. The thromboses occurred in the setting of right heart failure and after procedures that involved catheterization or cannulation ...
Benbow E W - - 1987
A case of disseminated zygomycosis is described, in which myocardial infarction rather than coincident coronary or heart disease was seen at necropsy. As zygomycosis is an opportunistic fungal infection, which tends to invade blood vessels, thereby causing thrombosis and infarction, it is surprising that cardiac disease is unusual and that ...
Merigian K S - - 1987
Cocaine has become the recreational drug of abuse of the eighties. The prevalence of cocaine has been manifesting increases in intoxications and poisonings. Acute overdoses have been associated with hyperthermia, agitation, paranoid ideation, status epilepticus, ventricular fibrillation, ventricular tachycardia, myocardial infarction, coma, and death. This is the first reported case ...
Høegholm A - - 1987
Recurrent syncopes due to acute circulatory failure occurred in a 40-years-old female with a massive right atrial thromboembolus which was detected by two-dimensional echocardiography (2 DE), and subsequently surgically removed. 2 DE is an excellent and rapid screening technique for the patients with right sided intracardiac masses. The use of ...
Isner J M - - 1986
The increasingly widespread use of cocaine in the United States has been accompanied and perhaps exacerbated by the misconception that the drug is not associated with serious medical complications. In particular, the potential for cocaine to precipitate life-threatening cardiac events needs to be reemphasized. We report the clinical and pathological ...
Diamond S M - - 1986
Bowel infarction as a frequent occurrence in patients with end-stage renal disease has not been previously recognized. This report describes 12 dialysis patients with nonocclusive bowel infarction. All patients with bowel infarction had large weight losses secondary to vomiting, diarrhea, or ultrafiltration when undergoing dialysis, preceding the development of this ...
Mathias D W - - 1986
The incidence of cocaine use is increasing in the United States among both adolescents and adults. Once thought to be a relatively safe street drug, cocaine has recently been implicated in 12 episodes of myocardial infarction. The case reports of these patients were retrospectively reviewed to determine the clinical and ...
Wiener R S - - 1986
Two young patients with dilated cardiomyopathies associated with long-term use of cocaine are described. A 42-year-old male cocaine abuser with normal coronary arteries experienced recurrent myocardial infarction, with development of a dilated, globally hypocontractile left ventricle. The second patient, a 28-year-old woman with a prominent history of inhaling vaporized cocaine ...
Chiu Y C - - 1986
Cocaine, the active alkaloid in coca leaf, is widely used as local anesthetic for otolaryngologic procedures. Our patient suffered an acute nontransmural myocardial infarction following clinical use of cocaine as topical anesthesia for nasal surgery, the first such case to be documented, to our knowledge. Although evidence documenting its cardiovascular ...
Chalmers A G - - 1986
As embolism of small bowel arteries carries the risk of bowel infarction, the technique is usually reserved for situations where a vasopressin infusion has failed to control bleeding. We report three cases in which embolisation was used as the primary treatment to control small bowel haemorrhage without the complication of ...
Anderson T E - - 1986
Previous experimental studies found that acute intoxication may alter the long-term outcome of standardized spinal cord injury resulting in increased spinal cord necrosis and impaired functional recovery. We examined the effects of acute intoxication (blood alcohol concentration of 100 mg/dl) on hemorrhage and axonal conduction three hours after moderate severity ...
Bernstein D - - 1986
Myocardial infarction in the perinatal period is a rare occurrence, usually associated with congenital heart lesions or isolated coronary artery abnormalities. In the absence of structural heart disease the most common etiologies are intrauterine asphyxia and thromboembolic coronary occlusion. A paradoxical embolus usually arises from a thrombus in the ductus ...
Nistal M - - 1986
A 74-year-old man was surgically treated owing to incarcerated right inguinal hernia. Following surgery, he developed a focal hemorrhagic testicular infarct localized in the anterior pole of the right testis. The cause of the infarct seemed to bei either thrombosis or compression by edema of the veins draining the testis.
Dooley S L - - 1985
Intrapartum events were studied in 272 patients with meconium-stained amniotic fluid. All infants underwent DeLee suction followed by intubation and 58 of 272 had meconium present below the vocal cords at delivery. Neither the total duration of variable fetal heart rate decelerations or a continuous saltatory pattern nor the presence ...
Boag F - - 1985
Following the drinking of 150 g of alcohol and a large amount of intra-nasal cocaine a previously healthy 31 year old man developed severe retrosternal pain and circulatory failure. An electrocardiogram showed supra-ventricular tachycardia with widespread ischaemic changes. Following electrical cardioversion electrocardiographic evidence of myocardial ischaemia persisted for 1 h. ...
Gram J - - 1985
In a longitudinal study the plasma levels of antithrombin-III, alpha 2-macroglobulin, alpha 2-antiplasmin, histidine-rich glycoprotein, and protein C were followed in two groups of patients with acute myocardial infarction (AMI), one with and one without deep vein thrombosis (DVT). None of the sequentially studied periods revealed significant differences between the ...
Masuda Y - - 1985
The cardiac responses to sympathetic nerve stimulation were measured in open-chest, anesthetized dogs before and after infusions of cocaine, which were given to inhibit the neuronal uptake of norepinephrine. Cocaine did not augment the inotropic or chronotropic responses, but it did retard their decay after cessation of sympathetic stimulation. Before ...
Kitching J P - - 1985
Nine feedlot cattle showed clinical signs consistent with those expected in thromboembolic meningoencephalitis. These signs included pyrexia, ataxia, posterior paresis, paralysis and coma. Brown necrotic foci with haemorrhagic borders were observed in the brains of three animals that had died. In these foci vasculitis, thrombosis, infarction and neutrophil infiltration were ...
Sharff J A - - 1984
The use of illicit cocaine continues to grow. This report is a documented case of renal infarction from intravenous cocaine use. The authors postulate that increased adrenergic stimulation from the intravenous cocaine, in association with an existing arterial thrombus, led to end organ infarction. This resulted in transient hypertension, but ...
Verheugt F W - - 1984
Since indium-111 platelet scintigraphy for the detection of left ventricular thrombosis often shows considerable non-specific blood pool activity a subtraction method using simultaneous technetium-99m blood pool scintigraphy was undertaken in 11 subjects with well documented remote myocardial infarction, who served as positive or negative controls, and in 18 consecutive patients ...
Kossowsky W A - - 1984
Six young cocaine users, median age 35.5 years (range 27 to 44 years) experienced acute myocardial infarction. The close temporal correlation in two cases between cocaine use and clinical infarction and the relative paucity of atherosclerotic blockage of the coronary arteries in the others, as demonstrated by autopsy or angiography, ...
Shea M J - - 1984
OKY-1581, a new thromboxane synthetase inhibitor, was studied in a conscious canine model of coronary thrombosis. After thoracotomy with placement of a left circumflex coronary artery flow probe and implantation of an electrode into the circumflex artery, animals were assigned randomly to the following groups: 0.9% NaCl vehicle control or ...
Sullivan D W - - 1984
A fatal myocardial infarction in a 22-year-old man with hemophilia A and a factor VIII inhibitor is described. The catastrophic event occurred while the patient was receiving high doses of unactivated prothrombin complex concentrates. Autopsy examination revealed myocardial hemorrhage with no evidence of coronary artery disease or thrombosis. There also ...
Ezekowitz M D - - 1984
Platelet scintigraphy with radioactive indium-111 may be used both to identify and to reflect the activity of thrombin in vivo in man. Forty-one patients with acute myocardial infarction were studied for active left ventricular thrombosis by platelet scintigraphy and followed until in-hospital death, discharge, or same-admission cardiac surgery for evidence ...
Johannessen K A - - 1984
In a prospective study of 90 consecutive patients with acute myocardial infarction, 15 (28.3%) of 53 patients with an anterior wall infarction developed a left ventricular thrombosis diagnosed by cross sectional echocardiography. Patients received anticoagulants only after a left ventricular thrombosis had been diagnosed. Twenty eight patients had an inferior ...
Marin-Garcia J - - 1984
Rocky Mountain spotted fever is an acute febrile illness with a significant mortality rate. Cardiac involvement has been sporadically reported, but is more common than appreciated from pathologic studies. The lesion is one of vasculitis, with secondary thrombosis and tissue necrosis. Cardiac function abnormalities may be detected by echocardiography and ...
Dale W A - - 1984
Retrospective study of 140 consecutive cases of nontraumatic acute ischemia of the extremities of 48 hours or less duration emphasizes differences in diagnostic features, treatment, and results among 71 patients with arterial embolism (11% mortality rate) and 69 with acute atherosclerotic thrombosis (3% mortality rate). The following principles of management ...
Effeney D J - - 1984
We determined the response of the common femoral vein to respiratory maneuvers using high resolution real-time ultrasound in 10 normal subjects, and we evaluated this modality in the diagnosis of iliofemoral venous thrombosis in 36 patients. We developed diagnostic criteria for assessment of the venous system and have confirmed them ...
Olson K R - - 1984
Nonocclusive intestinal infarction developed in a 29-year-old man after phenobarbital overdose. He was found 72 hours after the overdose, at which time examination of the abdomen disclosed no abnormalities and he was not hypotensive. During the next ten hours, abdominal distention, ileus, and gas within the intestinal wall and portal ...
Fiedler V B - - 1984
The thrombolytic and hemodynamic properties of intracoronary streptokinase (SK) application were studied in an in-vivo canine model with left circumflex coronary artery thrombosis, initiated by electrical stimulation (150 microA, DC for 6 h) of the artery's intima via an implanted silver wire. In pentobarbital-anesthetized, open-chest dogs acute myocardial ischemia was ...
Nanji A A - - 1984
We discuss a patient with cocaine intoxication in whom the initial presentation was that of asystole and ventricular fibrillation. Cocaine has a direct toxic action on the heart and also sensitizes cardiac tissue to the action of catecholamines. Cocaine intoxication should be considered in any patient with unexplained cardiac arrest ...
Hegedüs K - - 1984
Spinal cord infarction in the region of the posterior spinal arteries is reported in a 62-year-old woman. The softening was restricted to the lumbosacral region involving two segments. Sectioning the affected and adjacent segments serially no occlusion was found in the posterior spinal arteries. Besides the circumscribed infarction the microscopic ...
Lange H W - - 1983
Thirty-six hearts of patients who died with indwelling Swan-Ganz catheters in place were prospectively examined to assess the incidence and extent of localized lesions in the right side of the heart. Bland mural thrombosis in the superior vena cava, the right atrium and the pulmonary artery was found in 22 ...
Boyko O B - - 1983
A 60-year-old woman with livedo reticularis was examined for defective release of vascular plasminogen activator by a newly described chromogenic assay. Her activator level was only 0.007 Committee on Thrombolytic Agents (CTA) units/mL, compared with a mean of 0.19 CTA units/mL for 84 female controls. Subsequently, the patient died as ...
Goodnough L T - - 1983
Nine patients are described with hereditary clotting factor abnormalities and thrombosis and 35 others previously reported in the literature. An additional 11 patients with myocardial infarction observed by the authors and 12 more reported by others are also included. A patient with non-immune thrombocytopenia and myocardial infarction is presented, as ...
Muller J E - - 1983
There is intense scientific interest in the possibility that the acute administration of a fibrinolytic agent might be of benefit to patients with acute myocardial infarction. This hypothesis, which will soon be tested in a major trial by the National Heart, Lung, and Blood Institute, has emerged from a confluence ...
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