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Results 101 - 150 of 1002
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Sano Fumie - - 2008
We report a case of classic polyarteritis nodosa complicated with renal infarction. A 14-year-old boy manifested fever, abdominal pain, watery and bloody diarrhea, and weight loss. Laboratory findings indicated anemia, increased levels of C-reactive protein, and erythrocyte sedimentation rate. Lower gastrointestinal endoscopic examination revealed multiple colorectal ulcerations, and histopathological findings ...
Tiryakioglu Osman - - 2009
A left ventricular posterior-inferior free wall rupture without pseudo aneurysm following inferior myocardial infarction was identified in a 40-year-old male patient. Coronary angiography of the patient demonstrated a total occlusion of the circumflex artery. Repair of the rupture was performed during an elective surgery carried out 15 days after the ...
Hong Young Joon - - 2008
BACKGROUND: Ruptured plaques are associated with elevated C-reactive protein (CRP) that, in turn, are associated with a poor prognosis in acute myocardial infarction (AMI) patients. OBJECTIVES: The purpose of this study was to evaluate the impact of plaque rupture and elevated CRP on major adverse cardiac events (MACE) in patients ...
Park Choung Kyu - - 2008
Posterior wall rupture of the left ventricle is a rare but lethal complication after mitral valve replacement. We treated a patient with repeated left ventricular rupture. Initially, type 1 left ventricular rupture was repaired in the intensive care unit, but persistent bleeding occurred after the repair. We treated the bleeding ...
Grasso A E - - 2010
We present a case of lateral wall infarction in the territory of an anomalous circumflex artery without significant stenosis. The unusual location of the infarction suggests a causal relation with the anomalous artery through minor plaque rupture, which may have resulted from mechanical stress.
Antoniadis Antonios P - - 2008
Coronary ectasia is defined as local or generalized aneurysmal dilatation of the coronary arteries. The present review summarizes the molecular, cellular and vascular mechanisms which are involved in the pathobiology of coronary ectasia. Coronary ectasia likely represents an exaggerated form of expansive vascular remodeling (i.e. excessive expansive remodeling) in response ...
Higashikuni Yasutomi - - 2008
BACKGROUND: The difference in the culprit plaque composition of acute coronary syndrome (ACS) patients with and without the no-reflow phenomenon has not been fully evaluated. METHODS AND RESULTS: Intravascular ultrasound radiofrequency data of culprit plaques were obtained and analyzed in 49 ACS patients. The no-reflow phenomenon was defined as a ...
Narula Jagat - - 2008
Sudden cardiac death and acute myocardial infarction often occur as the first manifestation of coronary artery disease. Otherwise asymptomatic individuals with subclinical atherosclerosis almost always have a classic risk-factor profile and it is essential that they are identified before the occurrence of an acute coronary event. The ability to recognize ...
Cleutjens Kitty B J M - - 2008
Novel biomarkers, such as circulating (auto)antibody signatures, may improve early detection and treatment of ruptured atherosclerotic lesions and accompanying cardiovascular events, such as myocardial infarction. Using a phage-display library derived from cDNAs preferentially expressed in ruptured peripheral human atherosclerotic plaques, we performed serological antigen selection to isolate displayed cDNA products ...
Müller Ulrike - - 2008
Complications after acute myocardial infarction (AMI) concerning the wall structure may be a true aneurysm, intramyocardial dissection, rupture of the free left ventricular wall covered by pericardium or formation of pseudoaneurysm. Differentiation between these complications of AMI may be difficult as shown by the following case report but is of ...
Deniz Hayati - - 2008
OBJECTIVE: Posterior ventricular rupture is a rare and fatal complication of mitral valve surgery. This study is designed to define the risk factors for left ventricular rupture after mitral valve replacement and, especially, to find out if posterior leaflet preservation is protective for posterior ventricular rupture. METHODS: Between January 1996 ...
Kallikourdis Antonios - - 2008
BACKGROUND: Ventricular wall rupture and acute mitral regurgitation due to papillary muscle rupture post-acute myocardial infarction are rare and dramatic mechanical complications. The operative mortality of both complications remains extremely high but this is the only treatment which has greatly improved the prognosis. CASE PRESENTATION: We describe the course of ...
Gopal Ambarish - - 2008
Although left ventricular (LV) pseudoaneurysm is seen infrequently, it should be recognized and distinguished from the common type of left ventricular aneurysm. The diagnosis can be difficult and the lesions are prone to rupture, thus the condition is associated with a high rate of morbidity and mortality. LV pseudoaneurysms are ...
Worley Seth J - - 2008
Coronary vein rupture is a potential complication of venoplasty for LV lead placement. Vein rupture in a patient with a virgin pericardium would be anticipated to have a profound hemodynamic impact from bleeding into the pericardial space. This report describes an elderly woman with a virgin pericardial space who underwent ...
Dundon B K - - 2008
Lightning strike is the most common environmental cause of sudden cardiac death, but may also be associated with a myriad of injuries to various organ systems. Direct myocardial injury may be manifest as electrocardiographic alterations or elevation in cardiac-specific isoenzymes; however, significant electrical cardiac trauma appears uncommon. A case is ...
ElMaraghy Amr A Division of Orthopaedic Surgery, University of Toronto, Toronto, ON, - - 2008
Complete distal biceps tendon ruptures require prompt surgical management for optimal functional and aesthetic outcome. The need exists for a valid and reliable diagnostic tool to expedite surgical referral. We hypothesized complete distal biceps tendon ruptures result in an objectively measurable anatomic landmark (the distance between the antecubital crease of ...
van den Borne Susanne W M - - 2008
OBJECTIVES: Our goal was to evaluate intercellular adhesion complex proteins in myocardium in human infarct rupture. BACKGROUND: Infarct rupture, a fatal complication of myocardial infarction (MI), has been attributed to a defective cell adhesion complex in a transgenic mouse model. METHODS: Heart samples were collected from autopsies from infarct rupture ...
Uzun S - - 2008
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder characterized by intravascular hemolysis, hemoglobinuria, and thrombosis. Thrombotic attacks are life threatening and are responsible for nearly 50% of PNH-related deaths. Compared with thrombotic events, bleeding related to thrombocytopenia in PNH is quite rare. This report describes an atypical clinical presentation with ...
Sajja Lokeswara R - - 2008
Postinfarction rupture of the interventricular septum is usually fatal without prompt surgical intervention. Repair of postinfarction ventricular septal rupture by an endocardial patch technique with infarct exclusion is associated with less morbidity and mortality. The results of this repair in 22 consecutive patients were analyzed retrospectively. After myocardial infarction, 16 ...
Sartipy U - - 2008
Surgical ventricular restoration by the endoventricular patch technique (Dor procedure) is a surgical option designed to restore left ventricular shape and volume in patients with ischaemic heart disease and heart failure. Surgical ventricular restoration includes complete revascularisation, left ventricular reconstruction to restore near-normal shape and volume, and when necessary, mitral ...
Libby P - - 2008
Our evolving knowledge of the cellular and molecular mechanisms underlying atherosclerosis has helped uncover the underlying causes behind thrombotic complications of this disease. Most fatal coronary thrombosis result from fibrous cap rupture or superficial erosion. Recent research has established a role for matrix metalloproteinases in the regulation of aspects of ...
Ambrose John A - - 2008
The search to find the location of future plaque ruptures or plaque erosions leading to myocardial infarction (so-called "vulnerable plaques") is an important area of cardiovascular research. Systemic therapy, including use of statins, targets the vulnerable patient. However, adverse events cannot be completely eliminated with the appropriate application of systemic ...
D'Onofrio Augusto - - 2008
Left ventricular free wall rupture often presents with an abrupt onset and rapidly progresses towards cardiogenic shock or electromechanical dissociation. The diagnostic pathway is still a matter of debate: echocardiography is commonly decisive but the assessment of coronary artery status is essential in order to optimize the surgical procedure. However, ...
Spiel Alexander O - - 2008
von Willebrand factor (VWF) plays a pivotal role in platelet adhesion and aggregation at sites of high shear rates (eg, in coronary arteries that have stenotic or ruptured atherosclerotic plaque lesions). Numerous studies have investigated the relationship between VWF plasma levels and thromboembolic cardiovascular events. In contrast to the rather ...
Kpodonu Jacques - - 2008
Open surgical repair of aorto bronchial fistulas is associated with a high morbidity and mortality. Endovascular stent graft as an alternative therapy, though limited, has produced acceptable initial results, but few reports of mid-term follow-up are available. We report the mid-term results with the use of an endograft to treat ...
van den Borne Susanne W M - - 2009
BACKGROUND: Infarct rupture is a usually fatal complication of myocardial infarction (MI), for which no molecular mechanism has been described in humans. Experimental evidence in mouse models suggests that the degradation of the extracellular matrix by matrix metalloproteinases (MMPs) plays an important role in infarct rupture. The present study was ...
Leibecke Thorsten - - 2008
BACKGROUND: Posttraumatic and postoperative cardiac luxation represents a serious complication of pericardial rupture, and early diagnosis is important. The purpose of this study is to determine signs of left cardiac luxation on computed tomography (CT). METHODS: CT scans in nine patients with pericardial rupture and cardiac luxation after blunt chest ...
Viana-Tejedor Ana - - 2008
Ventricular septal rupture is an infrequent, but usually lethal, complication after myocardial infarction that typically occurs in elderly patients. Percutaneous closure of this complication has been performed in some cases with variable results. We report on the case of a 77-year-old female with a postinfarction ventricular septal rupture who underwent ...
Sai Krishna Cheemalapati - - 2008
Roller pumps are widely used for cardiopulmonary bypass in developing nations by virtue of proven safety during several years of institutional use and cost effectiveness. However, careful adjustment of roller occlusion is needed because they are known to cause spallation, tubing wear, and the occasional incident of rupture of tubing ...
Terashima Masayoshi - - 2008
Left ventricular free wall rupture (LVFWR) is a fetal complication of acute myocardial infarction. This study was conducted to test the feasibility of percutaneous intrapericardial fibrin-glue injection therapy (PIFIT) for LVFWR after acute myocardial infarction and to assess its clinical outcome. From January 2000 to December 2004, LVFWR was confirmed ...
Yang Yining - - 2008
Cardiac rupture is more prevalent in elderly patients with first onset of acute myocardial infarct (MI), but the mechanism remains unexplored. We investigated the differences in the incidence of cardiac rupture and early left ventricular (LV) remodeling following coronary artery ligation between old (12-mo) and young (3-mo) C57Bl/6 male mice ...
Cui Song - - 2008
BACKGROUND: Rupture of unstable plaque with subsequent thrombus formation is the common pathophysiological substrate of acute coronary syndrome (ACS). It is of potential significance to explore the blood indexes predicting plaque characteristics. We investigated the relationship among soluble CD105, hypersensitive C-reactive protein (hs-CRP), and coronary plaque morphology. METHODS: A clinical ...
Perugini Enrica - - 2008
We describe a rare case of post-infarction myocardial rupture leading to communication between the left ventricle and coronary sinus, which eventually led to a left-to-right shunt. The observation was made in an elderly woman with subacute infero-posterior myocardial infarction. Diagnosis was initially made by transthoracic echocardiography (elicited by the finding ...
Rentoukas Elias I - - 2008
Cardiac ruptures following acute myocardial infarction include rupture of the left ventricle free-wall, ventricular septal defects, and papillary muscle rupture. Double myocardial rupture is a rare complication of acute myocardial infarction (0.3 %) and the report of such cases is exclusively limited to a small series of autopsy studies. In ...
Brizzio Mariano E - - 2008
Chordae rupture is the most common cause of severe acute mitral insufficiency. Many different mechanisms can cause an acute chordal rupture: degenerative mitral valve disease, infective endocarditis, myocardial infarction, or a posttraumatic event. We present 2 cases of acute mitral regurgitation requiring urgent surgery due to a posterior leaflet chorda ...
Dencker Magnus - - 2008
BACKGROUND: Left ventricular free wall rupture is an uncommon but catastrophic event following myocardial infarction, and considered the second leading cause of death in acute myocardial infarct. Different types of rupture exist from acute to sub acute types, but prognosis is usually poor. Early recognition and aggressive treatment is recommended. ...
Stoodley Paul W - - 2008
The recent increase in the number of cases of left ventricular free wall rupture being diagnosed before death and in the number of surgical repairs attempted is largely due to echocardiography. We report a case that highlights the value of echocardiography in the diagnosis and treatment of left ventricular free ...
Leff Richard A - - 2008
Ventricular free wall rupture is a devastating complication of acute myocardial infarction. It occurs in 15-25% of fatal cases. However, the overall incidence in acute MI cases is about 2%. [1] Clinical markers suggesting free wall rupture include pulseless electrical activity in a first MI, and pericardial tamponade. Subacute rupture ...
Arnold Jayanth R - - 2008
Ventricular septal rupture is a rare complication of myocardial infarction. Despite a significant reduction in its incidence with reperfusion therapy, thrombolysis has been implicated in the pathogenesis of septal rupture. There is little information regarding the impact of glycoprotein IIb-IIIa receptor blockers on ventricular septal rupture. We report a case ...
Bartel Thomas - - 2008
It is unlikely that mechanical stress altering a single vulnerable plaque leads to myocardial infarction from almost simultaneous proximal atherothrombotic closure of the right coronary artery and the left anterior descending coronary artery. ACUTE MANAGEMENT: Immediate catheter diagnosis and revascularization including stent deployment restored TIMI III flow in both coronary ...
Loria Valentina - - 2008
Myeloperoxidase (MPO) is an enzyme stored in azurophilic granules of polymorphonuclear neutrophils and macrophages and released into extracellular fluid in the setting of inflammatory process. The observation that myeloperoxidase is involved in oxidative stress and inflammation has been a leading factor to study myeloperoxidase as a possible marker of plaque ...
Gregoric Igor D - - 2008
Complications of acute myocardial infarction have decreased in number and severity due to the application of early thrombolytic coronary revascularization techniques. Nonetheless, the mortality rate associated with these complications remains high. Ventricular septal rupture is one of the complications that can occur after myocardial infarction. In the treatment of postinfarction ...
Narducci Maria Lucia - - 2007
OBJECTIVES: We evaluated telomerase activity in circulating polymorphonuclear neutrophils (PMN) and in PMN isolated from coronary atherosclerotic plaques by a novel approach. BACKGROUND: Delayed apoptosis of PMN have been demonstrated in unstable angina (UA). These cells have a finite lifespan with low telomerase activity, a polymerase that extends telomeres, structures ...
Takumi Takuro - - 2007
OBJECTIVES: The purpose of this study was to test the hypothesis that the maximal temperature (Tmax) site, as measured by thermal wire, coincides with the culprit plaque by intravascular ultrasound (IVUS) in patients with acute myocardial infarction (AMI). BACKGROUND: Subsequent thrombosis developing to the proximal region from the site of ...
Tanaka Atsushi - - 2008
AIMS: In this study, we investigated the relationship between longitudinal morphology reconstructed from pre-intervention intravascular ultrasound (IVUS) images and thrombolysis in myocardial infarction (TIMI) flow grade at initial angiograms in the acute phase of acute coronary syndrome (ACS). METHODS AND RESULTS: Our patient population comprised 72 ACS patients in whom ...
De Maria Elia - - 2007
We report the case of an 18-year-old man, victim of a car accident, presenting with severe hypotension and signs of cardiac tamponade. Transoesophageal echocardiography was suggestive of right atrial free wall rupture. The patient underwent urgent cardiac surgery for repair of right atrial rupture. The immediate clinical outcome was favourable; ...
Yamada Ryotaro - - 2007
OBJECTIVES: Intermediate echogenic plaque without acoustic shadow on intravascular ultrasound (IVUS) imaging has been recognized as fibrous plaque. Such echogenic plaque with ultrasonic attenuation may have higher risk for distal flow disturbance (slow flow/no-reflow) during percutaneous coronary intervention. However, histological evaluation of plaque with ultrasonic attenuation has not been performed. ...
Kusama Ikuyoshi - - 2007
OBJECTIVES: We sought to assess whether coronary plaque rupture at culprit lesions is associated with infarct size in patients with anterior acute myocardial infarction (AMI). BACKGROUND: Some patients with AMI have large infarcts despite early reperfusion. Whether culprit plaque morphology impacts infarct size or not remains unknown. METHODS: Patients who ...
Khan Behram - - 2007
Myocardial abscess formation is a life-threatening complication that is frequently but not exclusively associated with infective endocarditis. To our knowledge there are only two case reports of myocardial abscess formation in hemodialysis patients. Only one of these reports describes a myocardial abscess of bacterial etiology secondary to an infected intravascular ...
Iida Ryoji - - 2007
A surgical patient with ventricular septal rupture after acute myocardial infarction is presented. The primary concern of general anesthesia was in the maintenance of systemic arterial pressure and reduction of afterload. General anesthesia was induced with a combination of fentanyl, ketamine, and propofol, which successfully suppressed fluctuations of hemodynamic variables ...
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