Search Results
Results 251 - 300 of 2524
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Cortese Bernardo B Interventional Cardiology, A.O. Fatebenefratelli, Milan, - - 2014
Primary percutaneous coronary intervention (PPCI) has dramatically changed the scenario of ST-segment elevation myocardial infarction, consistently decreasing mortality and morbidity. These goals have been reached thanks to multiple technical and pharmacological refinements. The prevention of ischaemic complications via a combined pharmacoinvasive approach in these patients should concomitantly avoid bleeding events. ...
Jolly Sanjit S SS Department of Medicine, McMaster University, Hamilton, Ontario, - - 2014
The major challenge in the treatment of ST-elevation myocardial infarction (STEMI) is not only restoration of normal coronary blood flow but also microvascular perfusion. In fact, both electrocardiographic (ST segment resolution) and angiographic measures of myocardial perfusion (myocardial blush grade) have been shown to predict mortality after primary percutaneous coronary ...
Diletti Roberto R Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The - - 2014
The present article focuses on recent innovations and possible future perspectives in the reperfusion treatment of ST-segment elevation myocardial infarction (STEMI). Among these, the shift from the femoral to the radial vascular access, the recent availability of bioresorbable coronary scaffolds, other innovative forms of stent specifically designed for STEMI patients, ...
Athyros Vasilios G VG Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippocrates Hospital, Thessaloniki, - - 2014
Abstract Administration of high intensity statins prior to percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) or stable coronary artery disease has been shown to reduce short-, mid, and long-term cardiovascular disease (CVD) morbidity and mortality as well as overall mortality compared with lower intensity statins or no statin ...
Pilgrim Thomas T Department of Cardiology, Swiss Cardiovascular Center, University Hospital, Bern, - - 2014
Refinements in stent design affecting strut thickness, surface polymer, and drug release have improved clinical outcomes of drug-eluting stents. We aimed to compare the safety and efficacy of a novel, ultrathin strut cobalt-chromium stent releasing sirolimus from a biodegradable polymer with a thin strut durable polymer everolimus-eluting stent. We did ...
Wu Guodong G Department of Cardiology, First Hospital of Jilin University, Changchun, - - 2014
It remains unclear whether the clinical outcomes of patients with acute myocardial infarction (AMI) receiving second- and first-generation drug-eluting stents (DES) are identical. The study aimed to investigate the differences in clinical utility between the two generations of DES in these specific subjects by a meta-analysis. We systemically searched PubMed ...
Paarup Dridi Nadia N Department of Cardiology, The Heart Centre , Rigshosptalet , Denmark - - 2014
Abstract Aim: To investigate whether an intensified antiplatelet regimen could improve prognosis in stable or non-ST elevation in acute coronary syndrome (ACS) patients exhibiting high on-treatment platelet reactivity (HTPR) on clopidogrel and treated with percutaneous coronary intervention (PCI). There is a wide variability in the platelet reactivity to clopidogrel and ...
Chin Calvin W L CW British Heart Foundation/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom & National Heart Center Singapore, Singapore - - 2014
-Electrocardiographic (ECG) left ventricular hypertrophy (LVH) with strain is associated with an adverse prognosis in aortic stenosis. We investigated the mechanisms and outcomes associated with ECG-strain. -One hundred and two patients (70 [63,75] years, 66% males, aortic valve area 0.9 [0.7,1.2] cm(2)) underwent ECG, echocardiography and cardiovascular magnetic resonance: the ...
Kaur Randhawa Puneet P Department of Pharmaceutical Sciences and Drug Research, Punjabi University Patiala, 147002 - - 2014
Ischemic preconditioning is an intrinsic process in which preconditioning ischemia (ischemia of shorter duration) protects the organs against the subsequent index ischemia (sustained ischemia). Remote ischemic preconditioning (RIPC) is an innovative treatment approach in which interspersed cycles of preconditioning ischemia followed by reperfusion to a remote organ (other than target ...
Lee Ho-Myung HM Department of Internal Medicine, Keimyung University School of Medicine, Daegu, - - 2014
Although complex bifurcation stenting in patients with non-left main (LM) bifurcation lesions has not yielded better clinical outcomes than simpler procedures, the utility of complex bifurcation stenting to treat LM bifurcation lesions has not yet been adequately explored. In the present study, patients who underwent LM-to-left anterior descending (LAD) coronary ...
Frey Ulrich H UH Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg-Essen und Universitätsklinikum Essen, Essen, Germany. Electronic address: - - 2014
The C825T polymorphism of the gene encoding the human G protein beta-3 subunit (GNB3) is associated with hypertension and obesity. Moreover, genotypes of the GNB3 polymorphism have been associated with development of coronary artery disease, and the 825T allele is thought to influence the process of atherosclerosis. However, the potential ...
Dyer Laura L McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599. Electronic address: - - 2014
The establishment of the coronary circulation is one of the final critical steps during heart development. Despite decades of research, our understanding of how the coronary vasculature develops and connects to the aorta remains limited. This review serves two specific purposes: it addresses recent advances in understanding the origin of ...
Tomizawa Nobuo N Department of Radiology, New Tokyo Hospital, Japan. Electronic address: - - 2014
The purpose was to investigate the diagnostic performance of coronary computed tomography angiography (CTA) when non-calcified uninterpretable segments were determined as either obstructive or patent. We also investigated the factors that could improve the diagnosis of CTA. A total of 268 patients without known coronary artery disease who were clinically ...
Tower-Rader Albree A Division of Cardiology, Department of Medicine, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, - - 2014
Ventricular septal myectomy in patients with obstructive hypertrophic cardiomyopathy (HC) has been shown to reduce left ventricular (LV) outflow tract (LVOT) gradient and improve symptoms, although little data exist regarding changes in left atrial (LA) volume and LV diastolic function after myectomy. We investigated changes in LA size and LV ...
Roberts Carey Camille CC Second Year, Georgetown University School of Medicine, Washington, DC; The Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, - - 2014
Described herein is a 67-year-old woman who underwent replacement of both tricuspid and pulmonic valves because of severe isolated right-sided systolic heart failure. The cause of the heart failure preoperatively was believed to be the result of left breast radiation a year earlier. At operation, however, the pulmonic valve was ...
Dudek Dariusz D Department of Interventional Cardiology, Jagiellonian University Medical College, Krakow, Poland. Electronic address: - - 2014
The ability of stent implantation to improve indexes of reperfusion may depend on the time to reperfusion in acute ST-segment elevation myocardial infarction (STEMI) and may also vary with stent type. The purpose of this prespecified analysis from the randomized MGUARD for Acute ST Elevation Reperfusion trial was to evaluate ...
Sara Leonardo L Heart Institute, InCor, University of São Paulo Medical School, São Paulo, - - 2014
Multi-detector computed tomography angiography (MDCTA) is a promising method for risk assessment of patients with acute chest pain. However, its diagnostic performance in higher-risk patients has not been investigated in a large international multicenter trial. Therefore, in the present study we sought to estimate the diagnostic accuracy of MDCTA to ...
Michael Tesfaldet T TT Knight Cardiovascular Institute, Oregon Health & Science University, Portland, - - 2014
To compare long-term clinical outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using the retrograde and antegrade approach. There is limited long-term clinical outcomes data on the retrograde approach to CTO PCI. We performed a retrospective analysis of the long-term clinical outcomes of 193 consecutive patients who underwent ...
Lee Seung-Yul SY Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, - - 2014
Objectives: We evaluated whether morphological characteristics of neointimal tissue of in-stent restenosis (ISR) lesions assessed by optical coherence tomography (OCT) affect peri-procedural elevation of creatine kinase-myocardial band (CK-MB). Background: The impact of neointimal characteristics of ISR lesions on peri-procedural myocardial injury has not been sufficiently investigated. Methods: A total of ...
Klug Gert G University Clinic of Internal Medicine III, Cardiology, Innsbruck Medical University, Anichstraße 35, A-6020 Innsbruck, - - 2014
Cardiac magnetic resonance (CMR) is a unique method to determine regional and local aortic stiffness parameters. Although various methods have been validated, there is no data in patients after acute ST-segment elevation myocardial infarction (STEMI). In the present study we assessed the feasibility of different CMR derived measures of aortic ...
Jiang Fangyong F Department of Cardiology, Liuzhou People's Hospital, Liuzhou, Guangxi, - - 2014
Statins reduce the incidence of cardiovascular events after percutaneous coronary intervention (PCI), but no clinical studies have investigated the role of statins in ischemia-reperfusion injury after PCI. Rosuvastatin could reduce ischemia-reperfusion injury in patients with acute coronary syndrome treated with PCI. We investigated the effects of rosuvastatin on ischemia-reperfusion injury ...
Lamberts Morten M aDepartment of Cardiology, Gentofte University Hospital, Hellerup, Copenhagen, Denmark bDepartment of Cardiology, Amphia Hospital, Breda, the - - 2014
The optimal antithrombotic therapy in patients with atrial fibrillation and coronary artery disease is controversial. The benefit of the combination of antithrombotic therapies remains debatable, and, as the bleeding risk is substantial, this calls for knowledge of the duration, and which and how many agents should be used. The first ...
Yildiz M M Cardiologist, Internal medicine Specialist and Physiologist, Department of Cardiology, Istanbul University Cardiology Institute, Istanbul, Turkey. - - 2014
Stent thrombosis is a serious complication in stent era. It can be presented as death, cardiogenic shock or a large non-fatal myocardial infarction, usually with ST elevation. Risks of stent thrombosis, stent thrombosis incidence and predictors are controversial issues due to sparse and controversial data. But all attending physicians should ...
Yildiz M - - 2014
Antiplatelet therapy plays an important role in the treatment of patients suffering from acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) in order to prevent atherothrombotic events and restenosis or ischemic reocclusion, respectively. Moreover, stent implantation is often performed along with PCI to ensure that the arteries remain ...
Yalcin Muhammed U MU Department of Cardiology, Hacettepe University, Ankara, - - 2014
Ultrasonographically guided percutaneous thrombin injection is the treatment of choice for iatrogenic femoral pseudoaneurysms, which mostly result from catheterization procedures. This is the first time, to our knowledge, that acute and subacute coronary stent thrombosis after percutaneous thrombin injection has been reported. This method should be reserved for selected patients, and special ...
Lai Chih-Hung CH Division of Interventional Cardiology, Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China; School of Medicine, National Yang-Ming University, Taipei, Taiwan, Republic of - - 2014
Coronary pseudoaneurysm is a rare complication of coronary intervention. We present a case with progression of coronary pseuodoaneurysm after a retrograde coronary intervention. According to the previous literature, conservative treatment with imaging follow-up is often adequate as an initial management of septal collateral perforation or pseudoaneurysm. However, in our case, ...
Salminen Pirjo-Riitta PR Department of Heart Disease, Haukeland University Hospital, Bergen, Norway Department of Clinical Science, Faculty of Medicine and Dentistry, University of Bergen, Norway - - 2014
Experimental studies have demonstrated that insulin elicits cardioprotection in coronary occlusion-reperfusion models. We studied the effects of intracoronary insulin on regional cardiac function in a porcine model with reperfusion after a critical coronary artery stenosis. In 20 anaesthetized pigs with an extracorporeal shunt from the brachiocephalic to the left anterior ...
Lambadiari Vaia - - 2014
BackgroundThe interplay between the novel adipokine retinol-binding protein-4 (RBP4) and coronary artery disease (CAD) is still obscure. We investigated the relationship between RBP4 levels and the presence and severity of angiographically proven CAD and determined its possible role in acute myocardial infarction (AMI).Methods305 individuals with angiographically proven CAD (CAD-patients), were ...
Chen Kang-Yin KY Cardiovascular Center, Korea University Guro Hospital, 80, Guro-dong, Guro-gu, Seoul 152-703, Republic of - - 2014
In contrast to many studies comparing everolimus-eluting stent (EES) with paclitaxel-eluting stent (PES), data directly comparing EES with sirolimus-eluting stent (SES) are limited, especially in patients with acute myocardial infarction (AMI). This study includes 2911 AMI patients treated with SES (n=1264) or EES (n=1701) in Korea Acute Myocardial Infarction Registry ...
Escárcega Ricardo O RO Interventional Cardiology, MedStar Washington Hospital Center, Washington, - - 2014
To assess the safety and efficacy everolimus-eluting stents (EES) compared with first-generation drug-eluting stents (DES) in patients with acute myocardial infarction (MI) undergoing primary percutaneous coronary intervention (PCI). EES have been associated with improved clinical outcomes compared to paclitaxel-eluting stents (PES) and with similar outcomes compared to sirolimus-eluting stents (SES). ...
Madhavan Mahesh V MV Department of Medicine, Division of Cardiology, New York-Presbyterian Hospital and the Columbia University Medical Center, New York, New - - 2014
Postprocedural anticoagulation (AC) after primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) may be administered for a number of specific therapeutic indications (e.g. atrial fibrillation or left ventricular thrombus). However, the safety and effectiveness of such post-PCI AC for specific indications are not well defined. Thus, we ...
Rischin Adam P AP Department of Cardiology, Frankston Hospital, Peninsula Health, Frankston, Victoria, Australia. Electronic address: - - 2014
We present the case of a 42 year-old woman admitted to hospital with ST-elevation myocardial infarction involving two separate coronary territories. Angiography revealed multi-embolic occlusions of her left anterior descending (LAD) and first obtuse marginal (OM1) coronary arteries. Transoesophageal echocardiogram (TOE) showed a lesion attached to the left cusp of ...
Di Lorenzo Emilio E Division of Cardiology, "S.G. Moscati", Avellino, - - 2014
The aim of the current study was to compare everolimus-eluting stents (EES) with sirolimus-eluting stents (SES) in patients undergoing primary angioplasty. Drug-eluting stents may offer benefits in terms of repeat revascularization. However, as shown for first-generation drug-eluting stents, they may be counterbalanced by a potential higher risk of stent thrombosis, ...
Abu-Laban Riyad B - - 2014
ABSTRACTExtracorporeal membrane oxygenation (ECMO) is a method to provide temporary cardiac and respiratory support to critically ill patients. In recent years, the role of ECMO in emergency departments (EDs) for select adults has increased. We present the dramatic case of a 29-year-old man who was placed on venoarterial ECMO for ...
Seadon Scott - - 2014
Clinical questionFollowing transient ischemic attack or acute minor stroke, does the combination of clopidogrel and aspirin reduce the risk of stroke greater than aspirin alone?Article chosenWang Y, Wang Y, Zhao X, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med 2013;369:11-9.ObjectiveThe primary ...
Kim Kun Il KI Department of Thoracic and Cardiovascular Surgery, Hallym University College of - - 2014
Myocardial infarction (MI) secondary to coronary artery fistula and the subsequent occlusion of the distal right coronary artery (RCA) after blunt chest trauma is a rare entity. Here, we describe a case of coronary artery fistula and occlusion with an inferior MI that occurred following blunt chest trauma. At the ...
Mazur M M Department of Anatomy, Jagiellonian University Medical College, Krakow, Poland. - - 2014
Invasive cardiac procedures, such as arrhythmia ablation, cardiac resynchronisation therapy, percutaneous mitral annuloplasty and retrograde cardioplegia delivery require cannulation of the coronary sinus (CS). Detailed knowledge of the CS ostium region, including recognition of the presence of the Thebesian valve which sometimes covers the sinus, is a key to successfully ...
Hirata Kazuhito K Division of Cardiology Okinawa Chubu Hospital, Uruma, - - 2014
A 34-year-old female with a history of systemic lupus erythematosus (SLE) developed an acute inferior myocardial infarction while hospitalized for methicillin-resistant Staphylococcus Aureus sepsis. An emergent coronary angiography revealed an ectatic proximal left coronary artery and a huge aneurysm (37 mm × 32 mm) in the mid-portion of the right ...
Shivkar Rajni Rajendra RR Post Graduate Student,Department of Biochemistry, B.J.Govt. Medical College Pune, India - - 2014
Coronary artery disease (CAD) is the leading cause of mortality and morbidity in the world. Current predictions estimate that by the year 2020 cardiovascular diseases, notably atherosclerosis will become the leading global cause of the total disease burden. Atherosclerosis of the Coronary artery causes myocardial infarction and angina pectoris. Endothelial ...
Harutyunyan Marina M Department of Medicine B, The Heart Centre, Rigshospitalet, Copenhagen University Hospital & Faculty of Health Sciences, Copenhagen, - - 2014
The aim was to investigate the inflammatory biomarker YKL-40 as a monitor of myocardial ischemia in patients with coronary artery disease (CAD). A total of 311 patients with stable CAD were included. Blood samples were taken at baseline, the day after coronary angiography and/or after percutaneous coronary intervention and after ...
Quintana Eduard E Division of Cardiovascular Surgery, Mayo Clinic College of Medicine, Rochester, Minn; Universitat de Barcelona, Barcelona, - - 2014
A proportion of patients experience a decrease in left ventricular (LV) ejection fraction (EF) after mitral valve repair; however, predictors and long-term consequences remain unclear. A study of 1705 patients with severe, degenerative mitral valve regurgitation and normal preoperative EF (>60%) undergoing mitral valve repair from 1993 to 2012 was ...
Stiermaier Thomas T Department of Internal Medicine - Cardiology, University of Leipzig - Heart Center, Leipzig, - - 2014
Despite intensive research efforts, the causative mechanisms of takotsubo cardiomyopathy (TC) are still unknown. Recently, morphologic characteristics of the left anterior descending coronary artery (LAD) have been proposed as a potential pathophysiological substrate. Hence, the aim of the present study was to evaluate the prevalence of myocardial bridging and LAD ...
Nizamuddin S L SL Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA. Electronic address: - - 2014
Spontaneous coronary artery dissection is an uncommon cause of acute coronary syndrome, occurring predominantly in women during and immediately after pregnancy; it carries a mortality rate of greater than 50%. While the exact etiology is unknown, possible contributing factors include pregnancy-related hormonal, connective tissue and hemodynamic changes. We present a ...
Grundeken Maik J MJ Heartcenter, Academic Medical Center-University of Amsterdam, Amsterdam, the - - 2014
Primary percutaneous coronary intervention (PCI) has considerably improved clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) when compared with thrombolytic therapy. Prognosis after primary PCI might be further improved by decreasing stent-related complications such as stent thrombosis. The STENTYS self-apposing stent has been shown to be superior compared ...
Galassi Alfredo Ruggero AR Department of Medical Sciences and Pediatrics, Catheterization Laboratory and Cardiovascular Interventional Unit, Division of Cardiology, Cannizzaro Hospital, University of Catania, Italy. Electronic address: - - 2014
A promising variant of the subintimal tracking and re-entry (STAR) technique, called "mini-STAR," has been recently described as a successful rescue technique after revascularization failure by conventional techniques for coronary chronic total occlusion (CTO). The current study enrolled patients with CTO who underwent successful revascularization by the mini-STAR technique as ...
Hoffmann Rainer R Department of Cardiology, Pneumology, Angiology and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany. Electronic address: - - 2014
Myocardial deformation analysis by speckle-tracking echocardiography (STE) has been used for analysis of myocardial viability and myocardial fibrosis. Patients with severe aortic stenosis are known to develop myocardial fibrosis. This study evaluated the association between myocardial fibrosis determined by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) and 2-dimensional STE ...
Farman Muhammad Tariq MT Jinnah Medical College Hospital; Karachi-Pakistan. - - 2014
To know the predictors of a successful outcome of percutaneous transvenous mitral commissurotomy (PTMC) other than described in the Wilkins scoring system. Two hundred fifty-eight consecutive patients were enrolled for this observational study in a tertiary care heart center of Pakistan who had a Wilkins score of ≤8. Patients with ...
Rácz Ildikó I Institute of Cardiology and Heart Surgery,University of Debrecen Clinical Center; Debrecen-Hungary. - - 2014
Wall motion abnormalities during acute ST-segment elevation myocardial infarction (STEMI) and the improvement after recanalization depend on the conditions of the coronary occlusion. Fifty-seven patients with first-ever STEMI due to one-artery occlusion, treated with primary PCI, were evaluated. Area at risk and left ventricular wall motion abnormalities were localized with ...
Song Pil Sang PS Division of Cardiology, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, South - - 2014
It is uncertain whether side branch predilatation before main vessel stenting is necessary. We evaluated the effect of side branch predilatation on outcomes in percutaneous coronary intervention for true nonleft main bifurcation determined by the Medina classification using the provisional approach. Target vessel failures (composite of cardiac death, myocardial infarction, ...
Nobre Christiane A - - 2014
Smoking is a risk factor for thromboangiitis obliterans (TAO, Buerger's disease) and arteriosclerosis, but there are few cases of coronary heart disease (CAD)-associated Buerger's disease. A literature search for articles in English, Spanish and French published between 1966 and 2012 on patients with coronary involvement and TAO revealed 12 patients. ...
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