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Law Whitney W Division of Critical Care Medicine, Rady Children's Hospital San Diego, San Diego, CA, - - 2014
A ten-year-old female was admitted with syncope and a myocardial infarction, was resuscitated, and was diagnosed with anomalous left coronary artery from right aortic sinus. After initial stabilization, she was on bed rest in the intensive care unit awaiting surgery and experienced sudden arrest and could not be resuscitated, resulting ...
Takahashi Shinya S Department of Department of Cardiovascular Surgery, Hiroshima University, Hiroshima, - - 2014
An 86-year-old woman presented with chest pain and discomfort. Echocardiography revealed severe aortic valve stenosis and asymmetric septal hypertrophy. Aortic valve replacement and myectomy were performed using a curved knife. The blade was U-shaped in cross-section, and was curved upward along the long axis. Hypertrophic septal myocardium was removed along ...
Park Kyoung-Ha KH 0000-0002-5935-8715 Cardiovascular Division, Department of Internal Medicine, Hallym University Medical Center, Anyang, - - 2014
Although the age-adjusted Framingham risk score (AFRS), flow-mediated dilation (FMD), brachial-ankle pulse wave velocity (baPWV), high-sensitivity C-reactive protein (hsCRP), fibrinogen, homocysteine, and free fatty acid (FFA) can predict future cardiovascular events (CVEs), a comparison of these risk assessments for patients with stable angina has not been reported. We enrolled 203 ...
Guenther Sabina P W SP Department of Cardiac Surgery, Ludwig-Maximilian University, Munich, - - 2014
Myocardial ischemia due to concomitant coronary artery disease (CAD) or coronary dissection in patients with acute aortic dissection type Stanford A (AADA) is associated with myocardial failure and poor outcomes. Preoperative coronary angiography in this group of patients is still debated. The use of CT scan to diagnose coronary affection ...
Ripley David P DP Multidisciplinary Cardiovascular Research Centre (MCRC) & Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, - - 2014
Coronary heart disease (CHD) is a leading cause of death and disability worldwide. International guidelines recommend cardiovascular magnetic resonance (CMR) as an investigative option in those presenting with chest pain to inform diagnosis, risk stratify and determine the need for revascularization. CMR offers a unique method to assess global and ...
Bailey Christopher W CW Department of Radiology, West Virginia University School of Medicine, West Virginia, - - 2014
We present a case of pericardioesophageal fistula formation in a 40 year old male who 23 days after undergoing a repeat ablation procedure for atrial fibrillation developed chest pressure, chills and diaphoresis. After initial labs and tests that demonstrated no evidence for acute myocardial ischemia, the patient underwent CT angiography ...
Carrizo Sebastián S Hemodynamics and Interventional Cardiology Unit, Department of Cardiology, University Hospital La Paz, Madrid, Spain. Electronic address: - - 2014
Clinical trials have shown that functional assessment of coronary stenosis by fractional flow reserve (FFR) improves clinical outcomes. Intravascular ultrasound (IVUS) complements conventional angiography, and is a powerful tool to assess atherosclerotic plaques and to guide percutaneous coronary intervention (PCI). Computational fluid dynamics (CFD) simulation represents a novel method for ...
Kim J-H JH Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, South - - 2014
Systolic and diastolic functions have been evaluated to predict outcome in congestive heart failure (CHF). Recently, tissue Doppler imaging (TDI) has become useful for the estimation of myocardial function in cardiac diseases of humans and animals. This study was designed to assess whether myocardial function as assessed by TDI is ...
Cassese Salvatore S Deutsches Herzzentrum, Technische Universität München, Lazarettstr. 36, 80636 Munich, Germany. Electronic address: - - 2014
Objective: The role of oral immunosuppressive therapy (OIT) to prevent restenosis after percutaneous coronary intervention (PCI) and stenting is still controversial. This study evaluates the impact of oral administration of prednisone or sirolimus to prevent restenosis. Methods: We conducted a meta-analysis of trials in which PCI-patients were randomized to bare ...
He Lingjuan L Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, - - 2014
Over the last two decades, genetic lineage tracing has allowed for the elucidation of the cellular origins and fates during both embryogenesis and in pathological settings in adults. Recent lineage tracing studies using Apln-CreER tool indicated that a large number of post-natal coronary vessels do not form from pre-existing vessels. ...
Carrascal Y Y Servicio de Cirugía Cardiaca, Hospital Clínico Universitario de Valladolid, Valladolid, España. Electronic address: - - 2014
To understand the risk factors and long-term impact and results of aortic valve surgery in patients over age 80. We consecutively evaluated 255 octogenarians who were operated on between 2000 and 2013 and referred for aortic valve disease (isolated or combined with coronary artery disease), which, even when associated with ...
O'Sullivan Crochan J CJ Department of Cardiology, Bern University Hospital, University of Bern, Bern, - - 2014
Low-flow, low-gradient severe aortic stenosis (AS) is characterised by a small aortic valve area (AVA) and low mean gradient (MG) secondary to a low cardiac output and may occur in patients with either a preserved or reduced left ventricular ejection fraction (LVEF). Symptomatic patients presenting with low-flow, low-gradient severe AS ...
Erlinge David D Department of Cardiology, Lund University, 22185 Lund, Sweden - - 2014
Intracoronary near-infrared spectroscopy (NIRS) in ST-segment elevation myocardial infarction (STEMI) has demonstrated substantial lipid in STEMI culprit plaques. Thrombus aspiration during primary PCI reduces distal embolization and improves reperfusion. This study was performed to examine if aspiration thrombectomy reduces the lipid content of acute coronary syndrome (ACS) culprit plaques. NIRS-IVUS ...
Verdoia M M Division of Cardiology, Azienda Ospedaliera-Universitaria "Maggiore della Carità", Eastern Piedmont University, Novara, - - 2014
High density lipoproteins (HDL) have been addressed as a potential strategy for cardiovascular prevention, with great controversies on pharmacological approaches for HDL-elevation. Our aim was to compare HDL-rising treatment with niacin or CETP-inhibitors with optimal medical therapy in cardiovascular outcome. Randomized trials were searched. Primary endpoint was cardiovascular death, secondary ...
Kamperidis Vasileios V Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, AHEPA University Hospital, Thessaloniki, - - 2014
The prognostic implications of flow, assessed by stroke volume index (SVi), and left ventricular (LV) global longitudinal strain on survival of patients with low-gradient severe aortic stenosis (AS) and preserved LV ejection fraction are debated. The aim of this study was to evaluate the impact of flow and LV global ...
Johnson Mark C MC Division of Pediatric Cardiology, Department of Pediatrics, Washington University School of Medicine/St. Louis Children's Hospital, St. Louis, - - 2014
Little is known about the clinical significance of coronary artery dilation (CAD) and left ventricular hypertrophy (LVH) in patients with sickle cell disease (SCD). In a retrospective cohort, we studied the prevalence of CAD and LVH in 101 children with SCD in comparison to 93 healthy African-American patients without SCD. ...
Jing Yan-Yan - - 2014
Percutaneous coronary intervention with stenting in patients with coronary atheromatous stenosis carry an inherent risk of affecting the baroreflex-mediated regulation of hemodynamic alterations, especially for heart rate and blood pressure. To the best of our knowledge, the vagal baroreflex activation associated with acute coronary stent thrombosis in patients who have ...
Demir Kenan - - 2014
Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO). The study population included 225 patients, a control group (n = 75), a coronary artery disease group (n = 75), ...
Sapontis James J St Luke's Mid America Heart Institute, Kansas City - - 2014
Technical advances and the development of the Hybrid algorithm have been associated with higher success rates in chronic total occlusion percutaneous coronary intervention (CTO-PCI). Nevertheless there are still intra-procedural obstacles that result in failure or prolonged procedure time. The Excimer coronary laser (EL) has been repurposed in CTO-PCI to overcome ...
Soofi Muhammad Adil MA Prince Salman Heart Center, King Fahad Medical - - 2014
Surgical mitral valve intervention is not considered suitable in patients with severe functional mitral regurgitation due to severe dilated cardiomyopathy and severe systolic dysfunction. In such patients percutaneous mitral valve intervention is the next best alternative. We are presenting case report of a patient who presented with severe dyspnea progressing ...
Yamamoto Hideya H Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health - - 2014
Coronary artery calcification (CAC) is a well-established surrogate marker of the total burden of coronary atherosclerosis. The CAC score, as measured on coronary computed tomography (CT), is associated with the prevalence of coronary artery disease (CAD) as well as cardiovascular morbidity and mortality. The CAC score is used to reclassify ...
Kawai Hideki H Department of Cardiology, Fujita Health University, Toyoake, Japan. Electronic address: - - 2014
Many patients with atrial fibrillation (AF) and coronary artery stent deployment are given both antiplatelet drug and warfarin. Little information is available as to the relationship between the antithrombotic therapies in the late phase after stenting and the clinical outcomes of these patients. We examined the clinical outcomes of AF ...
Sardella Gennaro G Gennaro Sardella, Rocco Edoardo Stio, Department of Cardiovascular, Respiratory, Nephrologic and Geriatric Sciences, "Sapienza" University of Rome, Policlinico Umberto I, 00161 Rome, - - 2014
Reperfusion of myocardial tissue is the main goal of primary percutaneous coronary intervention (PPCI) with stent implantation in the treatment of acute ST-segment elevation myocardial infarction (STEMI). Although PPCI has contributed to a dramatic reduction in cardiovascular mortality over three decades, normal myocardial perfusion is not restored in approximately one-third ...
Fernández-Rodríguez Diego D Diego Fernández-Rodríguez, Luis Alvarez-Contreras, Victoria Martín-Yuste, Salvatore Brugaletta, Montserrat Cardona, Manel Sabaté, Department of Cardiology, Hospital Clinic, 08036 Barcelona, - - 2014
To evaluate the impact of thrombus aspiration (TA) on procedural outcomes in a real-world ST-segment elevation myocardial infarction (STEMI) registry. From May 2006 to August 2008, 542 consecutive STEMI patients referred for primary or rescue percutaneous coronary intervention were enrolled and the angiographic results and stent implantation characteristics were compared ...
Dattilo Giuseppe G Giuseppe Dattilo, Matteo Casale, Vincenza Giugno, Lorenzo Camarda, Natascia Laganà, Gianluca Di Bella, Department of Clinical and Experimental Medicine, Section of Cardiology, University of Messina, 98125 Messina, - - 2014
Usually, cardiac calcifications are observed in aortic and mitral valves, atrio-ventricular plane, mitral annulus, coronary arteries, pericaridium (usually causing constrictive pericarditis) and cardiac masses. Calcifications of atrial walls are unusual findings that can be identified only using imaging with high spatial resolution, such as cardiac magnetic resonance and computed tomography. ...
Kumar Andreas A Andreas Kumar, Rodrigo Bagur, Patrick Béliveau, Jean-Michel Potvin, Pierre Levesque, Nancy Fillion, Benoit Tremblay, Valérie Gaudreault, Division of Cardiology, Department of Medicine, Quebec University Hospital Centre, Quebec, G1R 2J6, - - 2014
A 24-year-old healthy man consulted to our center because of typical on-and-off chest-pain and an electrocardiogram showing ST-segment elevation in inferior leads. An urgent coronary angiography showed angiographically normal coronary arteries. Cardiovascular magnetic resonance imaging confirmed acute myocarditis. Although acute myocarditis triggering coronary spasm is an uncommon association, it is ...
Vignali Luigi L Unità Operativa di Cardiologia, Azienda Ospedaliero-Universitaria, Parma, - - 2014
Objectives: The aim of this study was to compare long-term clinical outcomes in patients treated with new-generation DES or early-generation DES in a real-world registry. Background: New-generation drug-eluting stents have proved to be more effective and safer than early-generation DES in randomized trials. However, the effects of new-generation DES vs. ...
Wong Jim K JK Department of Anesthesia, Stanford University School of Medicine, Stanford, CA. Electronic address: - - 2014
To test the hypothesis that including preoperative electrocardiogram (ECG) characteristics with clinical variables significantly improves the new-onset postoperative atrial fibrillation prediction model. Retrospective analysis. Single-center university hospital. Five hundred twenty-six patients,≥18 years of age, who underwent coronary artery bypass grafting, aortic valve replacement, mitral valve replacement/repair, or a combination of ...
Hernando Lorenzo L Servicio de Cardiología, Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, Spain. Electronic address: - - 2014
The aim of this study was to analyze the prevalence, risk factors, and short- and long-term prognosis of patients with acute coronary syndrome and normal renal function who developed percutaneous coronary intervention-associated nephropathy. This was an observational, retrospective, single-center study with a prospective follow-up of 470 consecutive patients hospitalized for ...
Lee Seung-Pyo SP From the Cardiovascular Center (S.P.L., J.M.L., H.K.K., Y.J.K., D.W.S.), Department of Internal Medicine (S.P.L., J.M.L., H.K.K., Y.J.K., D.W.S.), and Department of Radiology (W.L., E.A.P.), Seoul National University College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South - - 2014
Purpose To assess whether native T1 mapping provides noninvasive estimation of diffuse myocardial fibrosis and whether it correlates with subclinical myocardial dysfunction in asymptomatic patients with aortic stenosis ( AS aortic stenosis ). Materials and Methods The local institutional review board approved the study, and all patients gave informed consent. ...
Madrid-Miller Alejandra - - 2014
Pro-inflammatory molecules and low-density lipoproteins play essential roles in the atherosclerosis. The aim of our study was to establish an association among the cytokines secreted by peripheral blood mononuclear cells and the serum concentration in patients with unstable angina and coronary outward remodeling before and after percutaneous coronary intervention. The ...
Savini Carlo C From the Departments of *Cardiac Surgery, and †Anesthesia and Resuscitation, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, - - 2014
Minimally invasive mitral valve surgery may require a prolonged period of myocardial ischemia. Cardioplegic solutions that necessitate a single dose for adequate myocardial protection are evoked to simplify surgery and result to be appealing in this setting. The aim of this study was to assess early outcomes after minimally invasive ...
Avanzini Andrea A Department of Mechanical and Industrial Engineering, University of Brescia, Brescia, Italy - - 2014
Our aim was to understand the structural and functional behaviour of a pericardial heart valve with biological leaflets attached externally to a stent. To our knowledge, there is little if any literature concerning these kinds of bioprosthetic heart valves, while there is more concerning bioprosthetic heart valves with leaflets mounted ...
Vos Nicola S NS Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The - - 2014
In primary percutaneous coronary intervention (PPCI), stenting has been shown to reduce the need for repeat target lesion revascularisation (TLR) compared to balloon angioplasty alone, but did not result in a reduction of recurrent myocardial infarction (MI) or cardiac death. Meanwhile, stent-related adverse events such as stent thrombosis continue to ...
Gandhi Sumeet S Terrence Donnelly Heart Centre, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada; Hamilton Health Sciences, McMaster University, Hamilton, Ontario, - - 2014
Current guideline-based recommendations for oral dual-antiplatelet therapy in an acute coronary syndrome (ACS) include the use of newer adenosine diphosphate receptor inhibitor (ADPri) regimens and agents. The Canadian ACS Reflective Program is a multicenter observational quality-enhancement project that compared the use of ADPri therapy in 2 phases (November 2011-March 2013 ...
Kajander Olli A OA Heart Hospital, Tampere University Hospital and School of Medicine, University of Tampere, PO Box 2000, Teiskontie 35, Tampere FI-33521, Finland - - 2014
Intracoronary thrombus is disrupted by stent deployment and confounded by the development of intrastent plaque prolapse. This study aims at investigating the feasibility and repeatability of thrombus quantification prior to stent implantation using optical coherence tomography (OCT) in ST-segment elevation myocardial infarction (STEMI) patients. Patients were enrolled in an OCT ...
Mahesh Saktheeswaran K SK Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, - - 2014
In addition to infundibular muscular hypertrophy and anomalous muscle bundles in the right ventricular body, large membranous septal aneurysms (MSA), sinus of valsalva aneurysms, and aneurysms derived from the embryonic venous valve protruding through the tricuspid valve can cause right ventricular outflow obstruction in a patient with ventricular septal defect. ...
Goto Kenji K Division of Cardiovascular Medicine, Yale University School of Medicine, New Haven, - - 2014
Although lesion complexity is predictive of outcomes after balloon angioplasty, it is unclear whether complex lesions continue to portend a worse prognosis in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) with contemporary interventional therapies. We sought to assess the impact of angiographic lesion complexity, defined by ...
Chaikriangkrai Kongkiat K Department of Medicine, Houston Methodist Hospital, Houston, - - 2014
The objective of this study was to examine the prognostic utility of cardiac magnetic resonance imaging (CMR) in patients with chronic mitral regurgitation undergoing mitral valve repair. This study is a prospectively enrolled observational cohort study of 48 consecutive patients with chronic mitral regurgitation who had preoperative evaluation with CMR ...
Thiele Holger H Department of Internal Medicine/Cardiology, University of Leipzig Heart Center, Leipzig, Germany; Medical Clinic II, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany. Electronic address: - - 2014
Aspiration thrombectomy in ST-segment elevation myocardial infarction is recommended by current guidelines based on several randomized trials. There are no trials assessing thrombectomy in non-ST-segment elevation myocardial infarction (NSTEMI) patients. The TATORT-NSTEMI (Thrombus Aspiration in Thrombus Containing Culprit Lesions in Non-ST-Elevation Myocardial Infarction) trial sought to assess the effect of ...
Inoue Takahiro T Department of Cardiac Surgery, The Jikei University, 3-25-8 Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan, - - 2014
Left ventricular pseudoaneurysm is a rare, but potentially fatal, condition that generally occurs as a complication of myocardial infarction, infective endocarditis, or cardiac surgery. Surgical repair is the treatment of first choice because of the marked risk of rupture, but deteriorated hemodynamics and complicated procedures to treat the pseudoaneurysm may ...
Peng Yuhong Y aDepartment of Cardiology, Second Hospital of Hebei Medical University bDepartment of Cardiology, Bethune International Peace Hospital, Hebei, People's Republic of - - 2014
The aim of this study was to examine the role of intracoronary anisodamine and diltiazem administration performed before stenting on the immediate angiographic and clinical outcome in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). STEMI patients during primary PCI were randomized to two bolus injections ...
Bening Constanze - - 2014
Myxomatous degeneration of the mitral valve is a common pathological finding in mitral valve surgery and the most common reason for severe mitral valve regurgitation. Considering the importance of right ventricular remodeling and global function after mitral valve surgery we tried to elucidate a possible association of myxomatous mitral valve ...
Veltman Caroline E CE Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; The Interuniversity Cardiology Institute of the Netherlands, Utrecht, The - - 2014
The presence of a left dominant coronary artery system is associated with worse outcome after ST-segment elevation myocardial infarction (STEMI) compared with right dominance or a balanced coronary artery system. However, the association between coronary arterial dominance and left ventricular (LV) function at follow-up after STEMI is unclear. The present ...
Hezzell Melanie J MJ Department of Clinical Science and Services, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, United Kingdom. Electronic address: - - 2014
To evaluate associations between N-terminal procollagen type III (PIIINP), a serum biomarker of collagen biosynthesis, and myocardial fibrosis in dogs with naturally-occurring myxomatous mitral valve disease (MMVD). Twenty-two dogs with echocardiographically-confirmed MMVD were prospectively recruited from a hospital population. All died as a result of MMVD and their hearts were ...
Kim Hack-Lyoung HL Seoul National University Boramae Medical Center, Seoul, - - 2014
This study was conducted to investigate the prognostic value of heart block among patients with acute myocardial infarction (AMI) treated with drug-eluting stents. A total of 13,862 patients with AMI, registered in the nation-wide AMI database from January 2005 to June 2013, were analyzed. Second- (Mobitz type I or II) ...
Han B Kelly BK The Children's Heart Clinic, Minneapolis, Minnesota; The Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota; Advanced Cardiac Imaging, The Minneapollis Heart Institute and Foundation, Minneapolis, Minnesota. Electronic address: - - 2014
Kawasaki disease (KD) is the leading cause of acquired coronary disease in children and may lead to subsequent myocardial ischemia and infarction. Because coronary computed tomographic angiography (CTA) is the most sensitive noninvasive test in patients with atherosclerosis, the aim of this study was to retrospectively evaluate coronary CTA performed ...
Moretti Michele M Division of Cardiology, Cardiovascular Department, "Ospedali Riuniti" and University of Trieste, Trieste, - - 2014
The aims of this study were to investigate the clinical outcomes of patients with low-gradient aortic stenosis despite preserved left ventricular ejection fraction and to assess reliable prognostic clinical-instrumental features in patients experiencing or not experiencing aortic valve replacement (AVR). Clinical-laboratory and echocardiographic data from 167 patients (median age 78 ...
Ogita Manabu M Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, - - 2014
Restenosis after vascular intervention remains a major clinical problem. Circulating LR11 has been shown a novel marker of intimal smooth muscle cell (SMC) proliferation in human and animal studies. The present study was performed to clarify the clinical significance of circulating LR11 in patients with stable angina pectoris after coronary ...
Badheka Apurva O AO Department of Cardiology, Detroit Medical Center, Detroit, Michigan. Electronic address: - - 2014
Contemporary large-scale data, regarding in-hospital outcomes depending on the types of stent used for percutaneous coronary intervention (PCI) is lacking. We queried the Healthcare Cost and Utilization Project's Nationwide Inpatient Sample from 2006 to 2011 using the International Classification of Diseases, Ninth Revision, Clinical Modification procedure code 36.06 (bare-metal coronary ...
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