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Results 101 - 150 of 2524
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Tuleta I I Department of Internal Medicine II, Cardiology and Pulmonology, University of Bonn, Bonn, Germany, - - 2014
Chlamydophila pneumoniae has been implicated in atherosclerosis/restenosis; however, clear evidence is missing. Therefore, the aim of our study was to examine the influence of intimal infection and systemic inflammation on cardiovascular complications after coronary intervention. 45 atheroma specimens from patients with symptomatic coronary artery disease who underwent directional endatherectomy with ...
Pfaff Dennis D Department of Biomedicine, Laboratory for Signal Transduction, University Hospital Basel and University of Basel, - - 2014
This study evaluated associations between plasma T-cadherin levels and severity of atherosclerotic disease. Three hundred and ninety patients undergoing coronary angiography were divided into three groups based on clinical and angiographic presentation: a group (n=40) with normal coronary arteries, a group (n=250) with chronic coronary artery disease and a group ...
Yamanaka Toshiaki T Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558, - - 2014
Contrast medium-induced acute kidney injury (CI-AKI) is a cardiovascular complication after myocardial infarction treated with emergency percutaneous coronary intervention. The aim of this randomized, sham-controlled trial was to evaluate the impact of remote ischemic preconditioning (RIPC) on CI-AKI in patients with ST-elevation myocardial infarction who received emergency primary percutaneous coronary ...
Kim Tae-Hoon TH Division of Cardiology, Department of Internal Medicine, Sejong General Hospital, Bucheon, Republic of - - 2014
We sought to evaluate the impact of final kissing balloon inflation (FKBI) after simple stent implantation for the treatment of non-left main true coronary bifurcation lesions in patients with acute coronary syndrome (ACS). Whether FKBI should be mandatory after simple stent implantation for the treatment of coronary bifurcation lesion is ...
Kurita Akiyoshi A Department of Cardiology, Aichi Medical University, Nagakute, - - 2014
The aim of this study was to assess the effect of eicosapentaenoic acid (EPA) on peri-procedural (type IVa) myocardial infarction (MI) following elective percutaneous coronary intervention (PCI). We analyzed data from 165 of 178 consecutive patients with stable angina pectoris who underwent de novo successful stent implantation in the native ...
Byrne Christina C Department of Cardiology, The Heart Center, Rigshospitalet, University of Copenhagen, Denmark. Electronic address: - - 2014
Type 1 diabetes mellitus (T1DM) is associated with an increased risk of ischemic heart disease (IHD). The relative contribution of structural and functional abnormalities of the coronary circulation determining clinically manifested IHD remains unknown. The aim of this study was to assess potential differences in myocardial perfusion at rest and ...
Jashari Haki H Department of Public Health and Clinical Medicine, Umeå University, - - 2014
Congenital aortic stenosis (CAS) and Coarctation of Aorta (CoA) represent two forms of pressure afterload that affect the left ventricle (LV), hence require regular echocardiographic monitoring. Subclinical dysfunction of the LV exists even in asymptomatic patients with preserved left ventricular ejection fraction (EF), implying low sensitivity of EF in predicting ...
Ielasi Alfonso A Hospital "Bolognini" Seriate, Bergamo, - - 2014
The elderly (≥75years) constitute a high-risk subset of patients who continue to have a poorer prognosis than non-elderly (<75years). Whether the effects of everolimus-eluting stent (EES) in ST-segment elevation myocardial infarction (STEMI) are independent of age has not been reported. We investigated the outcomes following primary PCI (PPCI) with bare-metal ...
de Matos Soeiro Alexandre A Unidade Clínica de Emergência do Instituto do Coração (InCor), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brasil. Electronic address: - - 2014
Due to the chronic inflammation associated with systemic lupus erythematosus (SLE), patients develop premature atherosclerosis and the disease is a risk factor for acute myocardial infarction. The best interventional treatment for acute coronary syndrome (ACS) in these patients is unclear. The objective of this study is to describe the baseline ...
Isshiki Takaaki T Division of Cardiology, Teikyo University - - 2014
Background:Prasugrel is being developed in Japan as an antiplatelet therapy for use during percutaneous coronary intervention (PCI). Up to 70% of Japanese patients with coronary artery disease undergo elective PCI. The PRASugrel For Japanese PatIenTs with Coronary Artery Diseases Undergoing Elective PCI (PRASFIT-Elective) study investigated the efficacy and safety of ...
Aggarwal Vikas V VA Eastern Colorado Health Care System, Denver, Colorado; University of Colorado, Denver Anschutz Medical Campus, Aurora, Colorado; Colorado Cardiovascular Outcomes Research Consortium, Denver, - - 2014
Stenosis of saphenous vein grafts (SVGs) after coronary artery bypass grafting (CABG) is common and often requires percutaneous coronary interventions (PCI) for treatment. However, data for the effectiveness of drug-eluting stents (DES) versus bare-metal stents (BMS) in SVG-PCI are unclear. This study sought to examine the association between DES versus ...
Verdecchia Paolo P From the Department of Medicine, Hospital of Assisi, Assisi, Italy (P.V.); Department of Medicine (G.R.) and Department of Cardiology and Cardiovascular Pathophysiology (F.A.), University Hospital of Perugia, Perugia, Italy; Department of Clinical Medicine and Cardiovascular and Immunological Sciences, University 'Federico II', Naples, Italy (B.T.); Department of Health Sciences, University of Milano-Bicocca and IRCCS Istituto Auxologico Italiano, Milano, Italy (G.M.); Department of Clinical Epidemiology and Biostatistics and Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada (J.P., P.G., K.T., S.Y.); and Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, United Kingdom (P.S.). - - 2014
Excessively high and low achieved blood pressure (BP) may be associated with a bad outcome in patients with coronary artery disease, the J curve phenomenon. The effect of BP changes from baseline in relation with the subsequent risk of stroke and myocardial infarction (MI) is unknown. Of the 25 620 ...
Courand Pierre-Yves PY Department of Interventional Cardiology, Hôpital Louis Pradel, Hospices Civils de Lyon and University Lyon1, Lyon, - - 2014
A 71-year-old man presented in emergency department for non-ST-elevation myocardial infarction. At admission, 12-lead ECG was in sinus rhythm without sign of myocardial ischemia, and troponin slightly increased. The only notable feature of the patient's medical history was single-vessel coronary artery disease revealed 10 years previously, treated by stenting of ...
Sabate Rotes Anna A Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota; Universitat Autònoma de Barcelona, Mayo Clinic, Rochester, - - 2014
Novel echocardiographic techniques based on myocardial deformation have not been extensively evaluated to assess right ventricular (RV) and left ventricular (LV) response after pulmonary valve replacement (PVR) in patients with repaired tetralogy of Fallot. Between 2003 and 2012, 133 patients undergoing first-time PVR after tetralogy of Fallot repair underwent echocardiographic ...
Carasso Shemy S Department of Cardiology, Rambam Health Care Campus, Haifa, Israel; Technion - Israel Institute of Technology, Haifa, Israel. Electronic address: - - 2014
Symptomatic patients with severe aortic stenosis (AS) demonstrate abnormal left ventricular (LV) mechanics. The aim of this study was to compare mechanics in asymptomatic and symptomatic patients with severe AS using two-dimensional myocardial strain imaging. One hundred fifty-four patients with severe AS (aortic valve area ≤ 1.0 cm(2)) referred to a ...
D'Andrea Antonello A Chair of Cardiology, Second University of Naples, AORN dei Colli, Monaldi Hospital, Naples, - - 2014
Transcatheter aortic valve implantation (TAVI) is an alternative treatment in surgically high-risk or inoperable patients with severe aortic stenosis (AS). The objective of this study was to analyze the effects of TAVI on left ventricular (LV) and left atrial (LA) longitudinal function assessed by speckle tracking echocardiography (2DSTE) in patients ...
Salters Charles C Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, - - 2014
Background: The incidence of adverse events with non-cardiac procedures (NCP) after the use of drug eluting stents (DES) is not well studied. We sought to determine the incidence and temporal trends of adverse events in patients undergoing NCP after coronary DES. Methods: We performed a retrospective review of patients receiving ...
Mayyas Fadia A FA Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, - - 2014
Inflammation plays a pivotal role in the etiology of coronary artery disease (CAD). Myeloperoxidase (MPO) is a potent inflammatory factor and a critical modulator of coronary inflammation and oxidative stress. The goal of this study was to determine the impact of the plasma MPO (pMPO) level and neutrophil/lymphocyte ratio on ...
Crouch Gareth G Flinders University, Adelaide, Australia; Department of Cardiothoracic Surgery, Flinders Medical Centre, Adelaide, - - 2014
There remains a paucity of mechanistic data on the effect of transcatheter aortic valve implantation (TAVI) on early left and right ventricular function and quantitative aortic valve regurgitation. We sought to assess and compare the early effects on myocardial function and aortic valve hemodynamics of TAVI and aortic valve replacement (AVR) using ...
Mihaila Sorina S Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Via Giustiniani 2, 35128, Padua, Italy, - - 2014
Mitral annulus (MA) geometry and dynamics are crucial for preserving normal mitral valve (MV) function. Static reference values for MA parameters have been reported, but the normal MA dynamics during the entire cardiac cycle remains controversial. MV full-volume datasets were obtained by three-dimensional transthoracic echocardiography from 50 healthy volunteers (18-74 years; ...
Lee Michael S MS Division of Cardiology, UCLA Medical Center, Los Angeles, - - 2014
Acute myocardial infarction (AMI) due to unprotected left main coronary artery (ULMCA) occlusion is an uncommon clinical entity, but often leads to severe clinical deterioration, with devastating sequalae including fatal arrhythmias, abrupt and severe circulatory failure, and sudden cardiac death. Recent guidelines have promoted treatment with percutaneous coronary intervention (PCI) ...
Dahal Khagendra K Department of Medicine, LRGHealthcare, Laconia, NH. Electronic address: - - 2014
Percutaneous coronary intervention (PCI) is preferred in patients with acute ST-elevation myocardial infarction (STEMI). In patients with acute STEMI with multivessel disease (MVD), the guidelines recommend culprit vessel PCI (CV-PCI) in the absence of hemodynamic instability. We performed a meta-analysis of all randomized controlled trials (RCTs) comparing multi-vessel PCI (MV-PCI) ...
Bezuidenhout Deon D Cardiovascular Research Unit, MRC IUCHRU, University of Cape Town, South Africa; Strait Access Technologies Pty Ltd, Cape Town, South Africa. Electronic address: - - 2014
Efficient function and long-term durability without the need for anticoagulation, coupled with the ability to be accommodated in many different types of patient, are the principal requirements of replacement heart valves. Although the clinical use of valves appeared to have remained steady for several decades, the evolving demands for the ...
Kaulitz Renate R Division Pediatric Cardiology and Pediatric Intensive Care Medicine,Tuebingen University Children's - - 2014
Myxoma in neonatal life are extremely rare. We report a case of a neonate with a pedunculated cardiac tumour arising from the anterolateral left ventricular wall protruding across the left ventricular outflow tract and continuously extending into the distal aortic arch. Surgical removal at 14 days of age via combined ...
Kusunose Kenya K Cleveland Clinic, Cleveland, - - 2014
-We sought to assess the utility of left ventricular global longitudinal strain (LV-GLS) in predicting mortality in moderate to severe and paradoxical severe aortic stenosis (AS) patients with preserved ejection fraction (EF). -We studied 395 AS patients (70±14 years, 57% men) with aortic valve area (AVA) <1.3 cm(2) evaluated between ...
Helder Meghana R K MR Division of Cardiovascular Surgery, Mayo Clinic, Rochester, - - 2014
The study objective was to analyze factors associated with left ventricular mass regression in patients undergoing aortic valve replacement with a newer bioprosthesis, the Trifecta valve pericardial bioprosthesis (St Jude Medical Inc, St Paul, Minn). A total of 444 patients underwent aortic valve replacement with the Trifecta bioprosthesis from 2007 ...
Erbel Raimund R Department of Cardiology, University of Duisburg-Essen, Essen, Germany. Electronic address: - - 2014
Novel bare metal stents with improved stent design may become a viable alternative to drug-eluting stents in certain patient groups, particularly, when long-term dual antiplatelet therapy should be avoided. The ENERGY registry aimed to assess the safety and benefits of a cobalt-chromium thin strut bare metal stent with a passive ...
Bavry Anthony A AA North Florida/South Georgia Veterans Health System, Gainesville, Florida; College of Medicine, University of Florida, Gainesville, Florida. Electronic address: - - 2014
To evaluate the impact of aspirin in stable coronary artery disease. We hypothesized that aspirin's benefit would be attenuated among individuals with stable coronary artery disease, but no prior ischemic event. Aspirin is recommended in stable coronary artery disease based on myocardial infarction and stroke studies. However, benefit among stable ...
Camici Paolo G PG Vita Salute University and Scientific Institute San Raffaele, Via Olgettina, 58, 20132 Milano, - - 2014
Obstructive disease of the epicardial coronary arteries was recognized as the cause of angina pectoris >2 centuries ago, and sudden thrombotic occlusion of an epicardial coronary artery has been established as the cause of acute myocardial infarction for >100 years. In the past 2 decades, dysfunction of the coronary microvasculature ...
Rodriguez Alfredo E AE Head Cardiac Unit, Otamendi Hospital, Buenos Aires School of Medicine. Electronic address: - - 2014
Diabetic patients have been associated with poor procedural and long term outcome if they were treated either with percutaneous coronary interventions or coronary artery bypass surgery. Recently several randomized clinical trials (RCT) in this subset of patients have been published showing a greater incidence of major adverse cardiovascular events, death/myocardial ...
Moesgaard S G SG Novo Nordisk A/S, Maaloev, - - 2014
This study investigated mitral valve and myocardial protein and gene expression of matrix metalloproteinases (MMPs), their tissue inhibitors (TIMPs) and transforming growth factor-β (TGF-β) and plasma MMP and TGF-β concentrations in age-matched dog groups euthanized due to either advanced myxomatous mitral valve disease (MMVD) or other reasons. Furthermore, echocardiographic data ...
Deng Qi-Wen QW Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, - - 2014
We assessed whether aortic cross-clamping or limb remote ischemic preconditioning improved postoperative outcomes, reduced myocardial injury and incidences of postoperative complications in patients undergoing on-pump coronary artery bypass grafting (CABG). PubMed, EMBASE, the Cochrane Library, and ClinicalTrials databases were searched for studies comparing the effects of ischemic preconditioning with no ...
Zuo Youmei Y Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University, Hefei 230022, - - 2014
This study investigated the effects of aortic root infusion of sufentanil on myocardial ischemia/reperfusion injury in patients undergoing elective mitral valve replacement (MVR) with cardiopulmonary bypass (CPB). A prospective, randomized, clinical study. A university-affiliated teaching hospital. Fifty-three adult patients undergoing elective MVR with CPB. Bolus infusions of sufentanil (0.2 μg/kg, ...
Kiviniemi Tuomas T Heart Center, Turku University Hospital and University of - - 2014
Background:We explored 12-month clinical outcomes of 929 patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) with bare-metal stents (BMS) vs. drug-eluting stents (DES) from the prospective multicenter AFCAS (Atrial Fibrillation undergoing Coronary Artery Stenting) registry.Methods and Results:Endpoints included the first occurrence of major adverse cardiac and cerebrovascular events (MACCE), defined ...
Yamashita Jun J Division of Cardiology, Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan, - - 2014
The range (0.75-0.80) of fractional flow reserve (FFR) is known as the gray zone. Although the FFR of 0.80 was recently adopted as the cutoff value for coronary revascularization, the long-term clinical outcomes of patients with angiographically moderate coronary artery stenosis (FFR: 0.75-0.80) remain unknown. The objective of the present ...
Capodanno Davide D aFerrarotto Hospital, University of Catania bETNA Foundation, Catania, - - 2014
To explore the ability of the ACEF score to predict the incidence of contrast-induced nephropathy (CIN) in patients undergoing coronary angiography with or without percutaneous coronary intervention. A total of 706 patients undergoing coronary angiography ± percutaneous coronary intervention (PCI) between March 2011 and October 2011 were analyzed. CIN using different definitions ...
Cassese Salvatore S Deutsches Herzzentrum, Technische Universität München and DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Lazarettstrasse, 36, Munich, - - 2014
Routine control angiography is a valuable tool with high-sensitivity in detecting restenosis after coronary stenting. However, the prognostic role of restenosis is still controversial. We investigated the impact of restenosis on 4-year mortality in patients undergoing routine control angiography after coronary stenting. All the patients undergoing successful implantation of coronary ...
Pan Ming-Sung - - 2014
The authors reported a 73-year-old alcoholic man with previously-unrecognized situs inversus totalis suffering from left upper quadrant pain. Acute myocardial infarction was diagnosed and coronary angioplasty was performed immediately. However, the massive bleeding from the previously-unfound hepatomas caused hypovolemic shock and fatal outcome. Situs inversus totalis is a rare congenital ...
Saw Jacqueline J From the Division of Cardiology, Vancouver General Hospital, Vancouver, BC (J.S., T.S., A.S., D.R., G.B.J.M.); Division of Cardiology, St Paul's Hospital, Vancouver, BC (E.A.); Division of Cardiology, St Michael's Hospital, Toronto, Ontario (C.E.B.); Division of Cardiology, Royal Jubilee Hospital, Victoria, BC (S.R.); Division of Cardiology, Royal Columbian Hospital, New Westminster, BC (T.V.); and BC Centre for Improved Cardiovascular Health, UBC, Vancouver, BC (M.G., K.H.). - - 2014
Nonatherosclerotic spontaneous coronary artery dissection (NA-SCAD) is underdiagnosed and an important cause of myocardial infarction in young women. The frequency of predisposing and precipitating conditions and cardiovascular outcomes remains poorly described. Patients with NA-SCAD prospectively evaluated (retrospectively or prospectively identified) at Vancouver General Hospital were included. Angiographic SCAD diagnosis was ...
Shishehbor Mehdi H MH Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: - - 2014
This study sought to examine operator experience measured by time-related variables on outcomes with protected carotid artery stenting (CAS). Studies on experience have focused on operator and institutional CAS volumes alone in the absence of a better metric. Using the CHOICE (Carotid Stenting for High Surgical-Risk Patients; Evaluating Outcomes Through the Collection ...
Koca Serhat S Department of Pediatric Cardiology, Yuksek Ihtisas Heart-Education and Research Hospital, Ankara, - - 2014
Incessant focal atrial tachycardia may be encountered in the pediatric age group although it is rarely seen. Ablation using radiofrequency or cryothermal energy is the preferred method for drug-resistant cases. Recently, 3D electroanatomic mapping systems have been increasingly used for mapping and ablation. In this report, we presented, for the ...
Ashikaga Takashi T Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo. Electronic address: - - 2014
Stent underexpansion is known as a major cause of restenosis and stent thrombosis in calcified coronary lesions. We report a case of calcified nodule pretreated with excimer laser coronary angioplasty (ELCA) in acute coronary syndrome (ACS). Excimer laser use altered underlying lesion morphology such as calcified nodule and accompanied plaque ...
Kim Jin-Jin JJ Cardiovascular Center and Cardiology Division, Seoul St. Mary's Hospital, The Catholic University of Korea, Banpodong 505, Seochogu, Seoul, 137-701, Republic of - - 2014
This study assessed the associations between microalbuminuria in asymptomatic patients with type 2 diabetes and the presence, extent, and severity of coronary atherosclerosis, as measured by coronary computed tomography angiography (CCTA), and the long-term clinical outcomes. In total, the study enrolled 284 consecutive eligible asymptomatic patients with type 2 diabetes ...
O H-Ici Darach D Unit for Cardiovascular Imaging, Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353, Berlin, Germany, - - 2014
Current models for real time study of the effects of myocardial ischemia/reperfusion have major limitations and confounders. Confounders include the surgical stresses of a thoracotomy and abnormal physiology of an open chest. The need to reposition the animal interferes with the study of the early changes associated with ischemia. Direct ...
Rossini R R Roberta Rossini, MD, PhD, Cardiovascular Department, A. O. PAPA GIOVANNI XXIII, Piazza OMS, 1, 24127 Bergamo, Italy, Tel.: +39 035 2673446, E-mail: - - 2014
The aim was to investigate the perioperative risk of ischaemic and bleeding events in patients with coronary stents undergoing cardiac and non-cardiac surgery and how these outcomes are affected by the perioperative use of oral antiplatelet therapy. This was a multicentre, retrospective, observational study conducted in patients with coronary stent(s) ...
Lee Juhyun J 1 Division of Cardiology, Department of Medicine, University of California , Los Angeles, Los Angeles, - - 2014
Abstract Myocardial infarction results in scar tissue and irreversible loss of ventricular function. Unlike humans, zebrafish has the capacity to remove scar tissue after injury. To assess ventricular function during repair, we synchronized microelectrocardiogram (μECG) signals with a high-frequency ultrasound pulsed-wave (PW) Doppler to interrogate cardiac hemodynamics. μECG signals allowed ...
Nippak Pria Md - - 2014
ST-elevation myocardial infarction (STEMI) remains the second leading cause of death in Canada. Primary percutaneous coronary intervention (PCI) has been recognized as an effective method for treating STEMI. Improved access to primary PCI can be achieved through the implementation of regional PCI centres, which was the impetus for implementing the ...
Bressan Michael M Cardiovascular Research Institute, University of California San Francisco, 555 Mission Bay Boulevard South, San Francisco, CA 94143-3120, - - 2014
Efficient blood flow depends on two developmental processes that occur within the atrioventricular junction (AVJ) of the heart: conduction delay, which entrains sequential chamber contraction; and valve formation, which prevents retrograde fluid movement. Defects in either result in severe congenital heart disease; however, little is known about the interplay between ...
Citro Rodolfo R Heart Department, University Hospital "San Giovanni di Dio e Ruggi d'Aragona" Salerno, Italy. Electronic address: - - 2014
Echocardiography is frequently the initial noninvasive imaging modality used to assess patients with takotsubo cardiomyopathy (TTC). Standard transthoracic echocardiography can provide, even in the acute care setting, useful information about left ventricular (LV) morphology as well as regional and global systolic or diastolic function. It allows the differentiation of different ...
Martens Thomas T Department of Cardiac Surgery, Ghent University Hospital, Ghent, Belgium. Electronic address: - - 2014
We present an unusual case of acute myocardial infarction by embolic obstruction of both the left anterior descending and right coronary arteries in a 14-year-old girl. Echocardiography showed mobile lesions on the mitral valve and into the left ventricular outflow tract with poor left ventricular function, eventually suggesting endocarditis. Successful ...
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