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Mayyas Fadia A FA Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, - - 2014
Inflammation plays a pivotal role in the etiology of coronary artery disease (CAD). Myeloperoxidase (MPO) is a potent inflammatory factor and a critical modulator of coronary inflammation and oxidative stress. The goal of this study was to determine the impact of the plasma MPO (pMPO) level and neutrophil/lymphocyte ratio on ...
Mihaila Sorina S Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Via Giustiniani 2, 35128, Padua, Italy, - - 2014
Mitral annulus (MA) geometry and dynamics are crucial for preserving normal mitral valve (MV) function. Static reference values for MA parameters have been reported, but the normal MA dynamics during the entire cardiac cycle remains controversial. MV full-volume datasets were obtained by three-dimensional transthoracic echocardiography from 50 healthy volunteers (18-74 years; ...
Lee Michael S MS Division of Cardiology, UCLA Medical Center, Los Angeles, - - 2014
Acute myocardial infarction (AMI) due to unprotected left main coronary artery (ULMCA) occlusion is an uncommon clinical entity, but often leads to severe clinical deterioration, with devastating sequalae including fatal arrhythmias, abrupt and severe circulatory failure, and sudden cardiac death. Recent guidelines have promoted treatment with percutaneous coronary intervention (PCI) ...
Kaulitz Renate R Division Pediatric Cardiology and Pediatric Intensive Care Medicine,Tuebingen University Children's - - 2014
Myxoma in neonatal life are extremely rare. We report a case of a neonate with a pedunculated cardiac tumour arising from the anterolateral left ventricular wall protruding across the left ventricular outflow tract and continuously extending into the distal aortic arch. Surgical removal at 14 days of age via combined ...
Kusunose Kenya K Cleveland Clinic, Cleveland, - - 2014
-We sought to assess the utility of left ventricular global longitudinal strain (LV-GLS) in predicting mortality in moderate to severe and paradoxical severe aortic stenosis (AS) patients with preserved ejection fraction (EF). -We studied 395 AS patients (70±14 years, 57% men) with aortic valve area (AVA) <1.3 cm(2) evaluated between ...
Camici Paolo G PG Vita Salute University and Scientific Institute San Raffaele, Via Olgettina, 58, 20132 Milano, - - 2014
Obstructive disease of the epicardial coronary arteries was recognized as the cause of angina pectoris >2 centuries ago, and sudden thrombotic occlusion of an epicardial coronary artery has been established as the cause of acute myocardial infarction for >100 years. In the past 2 decades, dysfunction of the coronary microvasculature ...
Zuo Youmei Y Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University, Hefei 230022, - - 2014
This study investigated the effects of aortic root infusion of sufentanil on myocardial ischemia/reperfusion injury in patients undergoing elective mitral valve replacement (MVR) with cardiopulmonary bypass (CPB). A prospective, randomized, clinical study. A university-affiliated teaching hospital. Fifty-three adult patients undergoing elective MVR with CPB. Bolus infusions of sufentanil (0.2 μg/kg, ...
Kiviniemi Tuomas T Heart Center, Turku University Hospital and University of - - 2014
Background:We explored 12-month clinical outcomes of 929 patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) with bare-metal stents (BMS) vs. drug-eluting stents (DES) from the prospective multicenter AFCAS (Atrial Fibrillation undergoing Coronary Artery Stenting) registry.Methods and Results:Endpoints included the first occurrence of major adverse cardiac and cerebrovascular events (MACCE), defined ...
Yamashita Jun J Division of Cardiology, Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan, - - 2014
The range (0.75-0.80) of fractional flow reserve (FFR) is known as the gray zone. Although the FFR of 0.80 was recently adopted as the cutoff value for coronary revascularization, the long-term clinical outcomes of patients with angiographically moderate coronary artery stenosis (FFR: 0.75-0.80) remain unknown. The objective of the present ...
Capodanno Davide D aFerrarotto Hospital, University of Catania bETNA Foundation, Catania, - - 2014
To explore the ability of the ACEF score to predict the incidence of contrast-induced nephropathy (CIN) in patients undergoing coronary angiography with or without percutaneous coronary intervention. A total of 706 patients undergoing coronary angiography ± percutaneous coronary intervention (PCI) between March 2011 and October 2011 were analyzed. CIN using different definitions ...
Cassese Salvatore S Deutsches Herzzentrum, Technische Universität München and DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Lazarettstrasse, 36, Munich, - - 2014
Routine control angiography is a valuable tool with high-sensitivity in detecting restenosis after coronary stenting. However, the prognostic role of restenosis is still controversial. We investigated the impact of restenosis on 4-year mortality in patients undergoing routine control angiography after coronary stenting. All the patients undergoing successful implantation of coronary ...
Pan Ming-Sung - - 2014
The authors reported a 73-year-old alcoholic man with previously-unrecognized situs inversus totalis suffering from left upper quadrant pain. Acute myocardial infarction was diagnosed and coronary angioplasty was performed immediately. However, the massive bleeding from the previously-unfound hepatomas caused hypovolemic shock and fatal outcome. Situs inversus totalis is a rare congenital ...
Saw Jacqueline J From the Division of Cardiology, Vancouver General Hospital, Vancouver, BC (J.S., T.S., A.S., D.R., G.B.J.M.); Division of Cardiology, St Paul's Hospital, Vancouver, BC (E.A.); Division of Cardiology, St Michael's Hospital, Toronto, Ontario (C.E.B.); Division of Cardiology, Royal Jubilee Hospital, Victoria, BC (S.R.); Division of Cardiology, Royal Columbian Hospital, New Westminster, BC (T.V.); and BC Centre for Improved Cardiovascular Health, UBC, Vancouver, BC (M.G., K.H.). - - 2014
Nonatherosclerotic spontaneous coronary artery dissection (NA-SCAD) is underdiagnosed and an important cause of myocardial infarction in young women. The frequency of predisposing and precipitating conditions and cardiovascular outcomes remains poorly described. Patients with NA-SCAD prospectively evaluated (retrospectively or prospectively identified) at Vancouver General Hospital were included. Angiographic SCAD diagnosis was ...
Shishehbor Mehdi H MH Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: - - 2014
This study sought to examine operator experience measured by time-related variables on outcomes with protected carotid artery stenting (CAS). Studies on experience have focused on operator and institutional CAS volumes alone in the absence of a better metric. Using the CHOICE (Carotid Stenting for High Surgical-Risk Patients; Evaluating Outcomes Through the Collection ...
Koca Serhat S Department of Pediatric Cardiology, Yuksek Ihtisas Heart-Education and Research Hospital, Ankara, - - 2014
Incessant focal atrial tachycardia may be encountered in the pediatric age group although it is rarely seen. Ablation using radiofrequency or cryothermal energy is the preferred method for drug-resistant cases. Recently, 3D electroanatomic mapping systems have been increasingly used for mapping and ablation. In this report, we presented, for the ...
Kim Jin-Jin JJ Cardiovascular Center and Cardiology Division, Seoul St. Mary's Hospital, The Catholic University of Korea, Banpodong 505, Seochogu, Seoul, 137-701, Republic of - - 2014
This study assessed the associations between microalbuminuria in asymptomatic patients with type 2 diabetes and the presence, extent, and severity of coronary atherosclerosis, as measured by coronary computed tomography angiography (CCTA), and the long-term clinical outcomes. In total, the study enrolled 284 consecutive eligible asymptomatic patients with type 2 diabetes ...
O H-Ici Darach D Unit for Cardiovascular Imaging, Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353, Berlin, Germany, - - 2014
Current models for real time study of the effects of myocardial ischemia/reperfusion have major limitations and confounders. Confounders include the surgical stresses of a thoracotomy and abnormal physiology of an open chest. The need to reposition the animal interferes with the study of the early changes associated with ischemia. Direct ...
Rossini R R Roberta Rossini, MD, PhD, Cardiovascular Department, A. O. PAPA GIOVANNI XXIII, Piazza OMS, 1, 24127 Bergamo, Italy, Tel.: +39 035 2673446, E-mail: - - 2014
The aim was to investigate the perioperative risk of ischaemic and bleeding events in patients with coronary stents undergoing cardiac and non-cardiac surgery and how these outcomes are affected by the perioperative use of oral antiplatelet therapy. This was a multicentre, retrospective, observational study conducted in patients with coronary stent(s) ...
Lee Juhyun J 1 Division of Cardiology, Department of Medicine, University of California , Los Angeles, Los Angeles, - - 2014
Abstract Myocardial infarction results in scar tissue and irreversible loss of ventricular function. Unlike humans, zebrafish has the capacity to remove scar tissue after injury. To assess ventricular function during repair, we synchronized microelectrocardiogram (μECG) signals with a high-frequency ultrasound pulsed-wave (PW) Doppler to interrogate cardiac hemodynamics. μECG signals allowed ...
Nippak Pria Md - - 2014
ST-elevation myocardial infarction (STEMI) remains the second leading cause of death in Canada. Primary percutaneous coronary intervention (PCI) has been recognized as an effective method for treating STEMI. Improved access to primary PCI can be achieved through the implementation of regional PCI centres, which was the impetus for implementing the ...
Bressan Michael M Cardiovascular Research Institute, University of California San Francisco, 555 Mission Bay Boulevard South, San Francisco, CA 94143-3120, - - 2014
Efficient blood flow depends on two developmental processes that occur within the atrioventricular junction (AVJ) of the heart: conduction delay, which entrains sequential chamber contraction; and valve formation, which prevents retrograde fluid movement. Defects in either result in severe congenital heart disease; however, little is known about the interplay between ...
Citro Rodolfo R Heart Department, University Hospital "San Giovanni di Dio e Ruggi d'Aragona" Salerno, Italy. Electronic address: - - 2014
Echocardiography is frequently the initial noninvasive imaging modality used to assess patients with takotsubo cardiomyopathy (TTC). Standard transthoracic echocardiography can provide, even in the acute care setting, useful information about left ventricular (LV) morphology as well as regional and global systolic or diastolic function. It allows the differentiation of different ...
Martens Thomas T Department of Cardiac Surgery, Ghent University Hospital, Ghent, Belgium. Electronic address: - - 2014
We present an unusual case of acute myocardial infarction by embolic obstruction of both the left anterior descending and right coronary arteries in a 14-year-old girl. Echocardiography showed mobile lesions on the mitral valve and into the left ventricular outflow tract with poor left ventricular function, eventually suggesting endocarditis. Successful ...
Law Whitney W Division of Critical Care Medicine, Rady Children's Hospital San Diego, San Diego, CA, - - 2014
A ten-year-old female was admitted with syncope and a myocardial infarction, was resuscitated, and was diagnosed with anomalous left coronary artery from right aortic sinus. After initial stabilization, she was on bed rest in the intensive care unit awaiting surgery and experienced sudden arrest and could not be resuscitated, resulting ...
Takahashi Shinya S Department of Department of Cardiovascular Surgery, Hiroshima University, Hiroshima, - - 2014
An 86-year-old woman presented with chest pain and discomfort. Echocardiography revealed severe aortic valve stenosis and asymmetric septal hypertrophy. Aortic valve replacement and myectomy were performed using a curved knife. The blade was U-shaped in cross-section, and was curved upward along the long axis. Hypertrophic septal myocardium was removed along ...
Park Kyoung-Ha KH 0000-0002-5935-8715 Cardiovascular Division, Department of Internal Medicine, Hallym University Medical Center, Anyang, - - 2014
Although the age-adjusted Framingham risk score (AFRS), flow-mediated dilation (FMD), brachial-ankle pulse wave velocity (baPWV), high-sensitivity C-reactive protein (hsCRP), fibrinogen, homocysteine, and free fatty acid (FFA) can predict future cardiovascular events (CVEs), a comparison of these risk assessments for patients with stable angina has not been reported. We enrolled 203 ...
Guenther Sabina P W SP Department of Cardiac Surgery, Ludwig-Maximilian University, Munich, - - 2014
Myocardial ischemia due to concomitant coronary artery disease (CAD) or coronary dissection in patients with acute aortic dissection type Stanford A (AADA) is associated with myocardial failure and poor outcomes. Preoperative coronary angiography in this group of patients is still debated. The use of CT scan to diagnose coronary affection ...
Ripley David P DP Multidisciplinary Cardiovascular Research Centre (MCRC) & Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, - - 2014
Coronary heart disease (CHD) is a leading cause of death and disability worldwide. International guidelines recommend cardiovascular magnetic resonance (CMR) as an investigative option in those presenting with chest pain to inform diagnosis, risk stratify and determine the need for revascularization. CMR offers a unique method to assess global and ...
He Lingjuan L Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, - - 2014
Over the last two decades, genetic lineage tracing has allowed for the elucidation of the cellular origins and fates during both embryogenesis and in pathological settings in adults. Recent lineage tracing studies using Apln-CreER tool indicated that a large number of post-natal coronary vessels do not form from pre-existing vessels. ...
Kim J-H JH Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, South - - 2014
Systolic and diastolic functions have been evaluated to predict outcome in congestive heart failure (CHF). Recently, tissue Doppler imaging (TDI) has become useful for the estimation of myocardial function in cardiac diseases of humans and animals. This study was designed to assess whether myocardial function as assessed by TDI is ...
Carrascal Y Y Servicio de Cirugía Cardiaca, Hospital Clínico Universitario de Valladolid, Valladolid, España. Electronic address: - - 2014
To understand the risk factors and long-term impact and results of aortic valve surgery in patients over age 80. We consecutively evaluated 255 octogenarians who were operated on between 2000 and 2013 and referred for aortic valve disease (isolated or combined with coronary artery disease), which, even when associated with ...
O'Sullivan Crochan J CJ Department of Cardiology, Bern University Hospital, University of Bern, Bern, - - 2014
Low-flow, low-gradient severe aortic stenosis (AS) is characterised by a small aortic valve area (AVA) and low mean gradient (MG) secondary to a low cardiac output and may occur in patients with either a preserved or reduced left ventricular ejection fraction (LVEF). Symptomatic patients presenting with low-flow, low-gradient severe AS ...
Erlinge David D Department of Cardiology, Lund University, 22185 Lund, Sweden - - 2014
Intracoronary near-infrared spectroscopy (NIRS) in ST-segment elevation myocardial infarction (STEMI) has demonstrated substantial lipid in STEMI culprit plaques. Thrombus aspiration during primary PCI reduces distal embolization and improves reperfusion. This study was performed to examine if aspiration thrombectomy reduces the lipid content of acute coronary syndrome (ACS) culprit plaques. NIRS-IVUS ...
Johnson Mark C MC Division of Pediatric Cardiology, Department of Pediatrics, Washington University School of Medicine/St. Louis Children's Hospital, St. Louis, - - 2014
Little is known about the clinical significance of coronary artery dilation (CAD) and left ventricular hypertrophy (LVH) in patients with sickle cell disease (SCD). In a retrospective cohort, we studied the prevalence of CAD and LVH in 101 children with SCD in comparison to 93 healthy African-American patients without SCD. ...
Jing Yan-Yan - - 2014
Percutaneous coronary intervention with stenting in patients with coronary atheromatous stenosis carry an inherent risk of affecting the baroreflex-mediated regulation of hemodynamic alterations, especially for heart rate and blood pressure. To the best of our knowledge, the vagal baroreflex activation associated with acute coronary stent thrombosis in patients who have ...
Demir Kenan - - 2014
Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO). The study population included 225 patients, a control group (n = 75), a coronary artery disease group (n = 75), ...
Sapontis James J St Luke's Mid America Heart Institute, Kansas City - - 2014
Technical advances and the development of the Hybrid algorithm have been associated with higher success rates in chronic total occlusion percutaneous coronary intervention (CTO-PCI). Nevertheless there are still intra-procedural obstacles that result in failure or prolonged procedure time. The Excimer coronary laser (EL) has been repurposed in CTO-PCI to overcome ...
Soofi Muhammad Adil MA Prince Salman Heart Center, King Fahad Medical - - 2014
Surgical mitral valve intervention is not considered suitable in patients with severe functional mitral regurgitation due to severe dilated cardiomyopathy and severe systolic dysfunction. In such patients percutaneous mitral valve intervention is the next best alternative. We are presenting case report of a patient who presented with severe dyspnea progressing ...
Yamamoto Hideya H Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health - - 2014
Coronary artery calcification (CAC) is a well-established surrogate marker of the total burden of coronary atherosclerosis. The CAC score, as measured on coronary computed tomography (CT), is associated with the prevalence of coronary artery disease (CAD) as well as cardiovascular morbidity and mortality. The CAC score is used to reclassify ...
Kawai Hideki H Department of Cardiology, Fujita Health University, Toyoake, Japan. Electronic address: - - 2014
Many patients with atrial fibrillation (AF) and coronary artery stent deployment are given both antiplatelet drug and warfarin. Little information is available as to the relationship between the antithrombotic therapies in the late phase after stenting and the clinical outcomes of these patients. We examined the clinical outcomes of AF ...
Sardella Gennaro G Gennaro Sardella, Rocco Edoardo Stio, Department of Cardiovascular, Respiratory, Nephrologic and Geriatric Sciences, "Sapienza" University of Rome, Policlinico Umberto I, 00161 Rome, - - 2014
Reperfusion of myocardial tissue is the main goal of primary percutaneous coronary intervention (PPCI) with stent implantation in the treatment of acute ST-segment elevation myocardial infarction (STEMI). Although PPCI has contributed to a dramatic reduction in cardiovascular mortality over three decades, normal myocardial perfusion is not restored in approximately one-third ...
Fernández-Rodríguez Diego D Diego Fernández-Rodríguez, Luis Alvarez-Contreras, Victoria Martín-Yuste, Salvatore Brugaletta, Montserrat Cardona, Manel Sabaté, Department of Cardiology, Hospital Clinic, 08036 Barcelona, - - 2014
To evaluate the impact of thrombus aspiration (TA) on procedural outcomes in a real-world ST-segment elevation myocardial infarction (STEMI) registry. From May 2006 to August 2008, 542 consecutive STEMI patients referred for primary or rescue percutaneous coronary intervention were enrolled and the angiographic results and stent implantation characteristics were compared ...
Dattilo Giuseppe G Giuseppe Dattilo, Matteo Casale, Vincenza Giugno, Lorenzo Camarda, Natascia Laganà, Gianluca Di Bella, Department of Clinical and Experimental Medicine, Section of Cardiology, University of Messina, 98125 Messina, - - 2014
Usually, cardiac calcifications are observed in aortic and mitral valves, atrio-ventricular plane, mitral annulus, coronary arteries, pericaridium (usually causing constrictive pericarditis) and cardiac masses. Calcifications of atrial walls are unusual findings that can be identified only using imaging with high spatial resolution, such as cardiac magnetic resonance and computed tomography. ...
Kumar Andreas A Andreas Kumar, Rodrigo Bagur, Patrick Béliveau, Jean-Michel Potvin, Pierre Levesque, Nancy Fillion, Benoit Tremblay, Valérie Gaudreault, Division of Cardiology, Department of Medicine, Quebec University Hospital Centre, Quebec, G1R 2J6, - - 2014
A 24-year-old healthy man consulted to our center because of typical on-and-off chest-pain and an electrocardiogram showing ST-segment elevation in inferior leads. An urgent coronary angiography showed angiographically normal coronary arteries. Cardiovascular magnetic resonance imaging confirmed acute myocarditis. Although acute myocarditis triggering coronary spasm is an uncommon association, it is ...
Vignali Luigi L Unità Operativa di Cardiologia, Azienda Ospedaliero-Universitaria, Parma, - - 2014
Objectives: The aim of this study was to compare long-term clinical outcomes in patients treated with new-generation DES or early-generation DES in a real-world registry. Background: New-generation drug-eluting stents have proved to be more effective and safer than early-generation DES in randomized trials. However, the effects of new-generation DES vs. ...
Wong Jim K JK Department of Anesthesia, Stanford University School of Medicine, Stanford, CA. Electronic address: - - 2014
To test the hypothesis that including preoperative electrocardiogram (ECG) characteristics with clinical variables significantly improves the new-onset postoperative atrial fibrillation prediction model. Retrospective analysis. Single-center university hospital. Five hundred twenty-six patients,≥18 years of age, who underwent coronary artery bypass grafting, aortic valve replacement, mitral valve replacement/repair, or a combination of ...
Hernando Lorenzo L Servicio de Cardiología, Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, Spain. Electronic address: - - 2014
The aim of this study was to analyze the prevalence, risk factors, and short- and long-term prognosis of patients with acute coronary syndrome and normal renal function who developed percutaneous coronary intervention-associated nephropathy. This was an observational, retrospective, single-center study with a prospective follow-up of 470 consecutive patients hospitalized for ...
Lee Seung-Pyo SP From the Cardiovascular Center (S.P.L., J.M.L., H.K.K., Y.J.K., D.W.S.), Department of Internal Medicine (S.P.L., J.M.L., H.K.K., Y.J.K., D.W.S.), and Department of Radiology (W.L., E.A.P.), Seoul National University College of Medicine, 101 Daehak-ro, Jongro-gu, Seoul 110-744, South - - 2014
Purpose To assess whether native T1 mapping provides noninvasive estimation of diffuse myocardial fibrosis and whether it correlates with subclinical myocardial dysfunction in asymptomatic patients with aortic stenosis ( AS aortic stenosis ). Materials and Methods The local institutional review board approved the study, and all patients gave informed consent. ...
Madrid-Miller Alejandra - - 2014
Pro-inflammatory molecules and low-density lipoproteins play essential roles in the atherosclerosis. The aim of our study was to establish an association among the cytokines secreted by peripheral blood mononuclear cells and the serum concentration in patients with unstable angina and coronary outward remodeling before and after percutaneous coronary intervention. The ...
Savini Carlo C From the Departments of *Cardiac Surgery, and †Anesthesia and Resuscitation, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, - - 2014
Minimally invasive mitral valve surgery may require a prolonged period of myocardial ischemia. Cardioplegic solutions that necessitate a single dose for adequate myocardial protection are evoked to simplify surgery and result to be appealing in this setting. The aim of this study was to assess early outcomes after minimally invasive ...
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