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Barbanti Marco M Ferrarotto Hospital, University of Catania, Catania, Italy; ETNA Foundation, Catania, Italy. Electronic address: - - 2014
The aim of this study was to assess the incidence and clinical impact of balloon post-dilation (BPD) after transcatheter aortic valve replacement (TAVR) with the CoreValve prosthesis (Medtronic Inc., Minneapolis, Minnesota). BPD is a widely adopted strategy to reduce the degree of paraprosthetic regurgitation in case of transcatheter heart valve underexpansion. However, ...
Tona F F Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy. Electronic address: - - 2014
Coronary allograft vasculopathy (CAV) involves both epicardial vessels and coronary microcirculation. Little is known about the effect of everolimus on coronary microvasculopathy in heart transplantation (HT). The aim of our study was to assess the pathological substrate of coronary flow reserve (CFR) impairment in HT patients and the effect of ...
de Luna Antonio Bayés AB Santa Creu i Sant Pau Hospital, Cardiovascular Research Center, CSIC-ICCC, Barcelona, - - 2014
We will focus our attention in this article in the ECG changes of classical Prinzmetal angina that occur during occlusive proximal coronary spasm usually in patients with normal or noncritical coronary stenosis. The most important ECG change during a focal proximal coronary spasm is in around 50% of cases the ...
Pokorny Saskia S Department of Cardiovascular Surgery, Christian-Albrechts-University of Kiel, School of Medicine, Kiel, - - 2014
Aims: The evaluation of in vivo shaping of mitral valved stent prototypes using cardiac computed tomography (CT) was the focus of this study. Methods and results: Twelve pigs received a self-expanding mitral valved stent, composed of an atrial element connected to a tubular ventricular body at a modified angle (45°, ...
Retzer Elizabeth M EM Section of Cardiology, Department of Medicine, The University of Chicago, Chicago, - - 2014
Iatrogenic membranous ventricular septal defects (VSD) are rare complications of cardiothoracic surgery, most commonly seen as a complication of aortic valve replacements. An iatrogenic VSD can lead to right sided heart failure, systemic hypoxia, and arrhythmias, and closure is often necessary. Given the increased mortality associated with repeat surgical procedures, ...
Sulaiman Helmi - - 2014
This case report describes a case of presumed acute myocardial infarction in a returned traveler who was later diagnosed to have severe malaria. Emergency coronary angiography was normal and subsequent peripheral blood film was positive for Plasmodium falciparum.
Cortese Bernardo B Interventional Cardiology, A.O. Fatebenefratelli, Milan, - - 2014
Primary percutaneous coronary intervention (PPCI) has dramatically changed the scenario of ST-segment elevation myocardial infarction, consistently decreasing mortality and morbidity. These goals have been reached thanks to multiple technical and pharmacological refinements. The prevention of ischaemic complications via a combined pharmacoinvasive approach in these patients should concomitantly avoid bleeding events. ...
Jolly Sanjit S SS Department of Medicine, McMaster University, Hamilton, Ontario, - - 2014
The major challenge in the treatment of ST-elevation myocardial infarction (STEMI) is not only restoration of normal coronary blood flow but also microvascular perfusion. In fact, both electrocardiographic (ST segment resolution) and angiographic measures of myocardial perfusion (myocardial blush grade) have been shown to predict mortality after primary percutaneous coronary ...
Diletti Roberto R Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The - - 2014
The present article focuses on recent innovations and possible future perspectives in the reperfusion treatment of ST-segment elevation myocardial infarction (STEMI). Among these, the shift from the femoral to the radial vascular access, the recent availability of bioresorbable coronary scaffolds, other innovative forms of stent specifically designed for STEMI patients, ...
Athyros Vasilios G VG Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippocrates Hospital, Thessaloniki, - - 2014
Abstract Administration of high intensity statins prior to percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) or stable coronary artery disease has been shown to reduce short-, mid, and long-term cardiovascular disease (CVD) morbidity and mortality as well as overall mortality compared with lower intensity statins or no statin ...
Pilgrim Thomas T Department of Cardiology, Swiss Cardiovascular Center, University Hospital, Bern, - - 2014
Refinements in stent design affecting strut thickness, surface polymer, and drug release have improved clinical outcomes of drug-eluting stents. We aimed to compare the safety and efficacy of a novel, ultrathin strut cobalt-chromium stent releasing sirolimus from a biodegradable polymer with a thin strut durable polymer everolimus-eluting stent. We did ...
Paarup Dridi Nadia N Department of Cardiology, The Heart Centre , Rigshosptalet , Denmark - - 2014
Abstract Aim: To investigate whether an intensified antiplatelet regimen could improve prognosis in stable or non-ST elevation in acute coronary syndrome (ACS) patients exhibiting high on-treatment platelet reactivity (HTPR) on clopidogrel and treated with percutaneous coronary intervention (PCI). There is a wide variability in the platelet reactivity to clopidogrel and ...
Chin Calvin W L CW British Heart Foundation/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom & National Heart Center Singapore, Singapore - - 2014
-Electrocardiographic (ECG) left ventricular hypertrophy (LVH) with strain is associated with an adverse prognosis in aortic stenosis. We investigated the mechanisms and outcomes associated with ECG-strain. -One hundred and two patients (70 [63,75] years, 66% males, aortic valve area 0.9 [0.7,1.2] cm(2)) underwent ECG, echocardiography and cardiovascular magnetic resonance: the ...
Kaur Randhawa Puneet P Department of Pharmaceutical Sciences and Drug Research, Punjabi University Patiala, 147002 - - 2014
Ischemic preconditioning is an intrinsic process in which preconditioning ischemia (ischemia of shorter duration) protects the organs against the subsequent index ischemia (sustained ischemia). Remote ischemic preconditioning (RIPC) is an innovative treatment approach in which interspersed cycles of preconditioning ischemia followed by reperfusion to a remote organ (other than target ...
Lee Ho-Myung HM Department of Internal Medicine, Keimyung University School of Medicine, Daegu, - - 2014
Although complex bifurcation stenting in patients with non-left main (LM) bifurcation lesions has not yielded better clinical outcomes than simpler procedures, the utility of complex bifurcation stenting to treat LM bifurcation lesions has not yet been adequately explored. In the present study, patients who underwent LM-to-left anterior descending (LAD) coronary ...
Dyer Laura L McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599. Electronic address: - - 2014
The establishment of the coronary circulation is one of the final critical steps during heart development. Despite decades of research, our understanding of how the coronary vasculature develops and connects to the aorta remains limited. This review serves two specific purposes: it addresses recent advances in understanding the origin of ...
Tomizawa Nobuo N Department of Radiology, New Tokyo Hospital, Japan. Electronic address: - - 2014
The purpose was to investigate the diagnostic performance of coronary computed tomography angiography (CTA) when non-calcified uninterpretable segments were determined as either obstructive or patent. We also investigated the factors that could improve the diagnosis of CTA. A total of 268 patients without known coronary artery disease who were clinically ...
Tower-Rader Albree A Division of Cardiology, Department of Medicine, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, - - 2014
Ventricular septal myectomy in patients with obstructive hypertrophic cardiomyopathy (HC) has been shown to reduce left ventricular (LV) outflow tract (LVOT) gradient and improve symptoms, although little data exist regarding changes in left atrial (LA) volume and LV diastolic function after myectomy. We investigated changes in LA size and LV ...
Roberts Carey Camille CC Second Year, Georgetown University School of Medicine, Washington, DC; The Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, - - 2014
Described herein is a 67-year-old woman who underwent replacement of both tricuspid and pulmonic valves because of severe isolated right-sided systolic heart failure. The cause of the heart failure preoperatively was believed to be the result of left breast radiation a year earlier. At operation, however, the pulmonic valve was ...
Michael Tesfaldet T TT Knight Cardiovascular Institute, Oregon Health & Science University, Portland, - - 2014
To compare long-term clinical outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using the retrograde and antegrade approach. There is limited long-term clinical outcomes data on the retrograde approach to CTO PCI. We performed a retrospective analysis of the long-term clinical outcomes of 193 consecutive patients who underwent ...
Lee Seung-Yul SY Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, - - 2014
Objectives: We evaluated whether morphological characteristics of neointimal tissue of in-stent restenosis (ISR) lesions assessed by optical coherence tomography (OCT) affect peri-procedural elevation of creatine kinase-myocardial band (CK-MB). Background: The impact of neointimal characteristics of ISR lesions on peri-procedural myocardial injury has not been sufficiently investigated. Methods: A total of ...
Klug Gert G University Clinic of Internal Medicine III, Cardiology, Innsbruck Medical University, Anichstraße 35, A-6020 Innsbruck, - - 2014
Cardiac magnetic resonance (CMR) is a unique method to determine regional and local aortic stiffness parameters. Although various methods have been validated, there is no data in patients after acute ST-segment elevation myocardial infarction (STEMI). In the present study we assessed the feasibility of different CMR derived measures of aortic ...
Jiang Fangyong F Department of Cardiology, Liuzhou People's Hospital, Liuzhou, Guangxi, - - 2014
Statins reduce the incidence of cardiovascular events after percutaneous coronary intervention (PCI), but no clinical studies have investigated the role of statins in ischemia-reperfusion injury after PCI. Rosuvastatin could reduce ischemia-reperfusion injury in patients with acute coronary syndrome treated with PCI. We investigated the effects of rosuvastatin on ischemia-reperfusion injury ...
Lamberts Morten M aDepartment of Cardiology, Gentofte University Hospital, Hellerup, Copenhagen, Denmark bDepartment of Cardiology, Amphia Hospital, Breda, the - - 2014
The optimal antithrombotic therapy in patients with atrial fibrillation and coronary artery disease is controversial. The benefit of the combination of antithrombotic therapies remains debatable, and, as the bleeding risk is substantial, this calls for knowledge of the duration, and which and how many agents should be used. The first ...
Yildiz M M Cardiologist, Internal medicine Specialist and Physiologist, Department of Cardiology, Istanbul University Cardiology Institute, Istanbul, Turkey. - - 2014
Stent thrombosis is a serious complication in stent era. It can be presented as death, cardiogenic shock or a large non-fatal myocardial infarction, usually with ST elevation. Risks of stent thrombosis, stent thrombosis incidence and predictors are controversial issues due to sparse and controversial data. But all attending physicians should ...
Yildiz M - - 2014
Antiplatelet therapy plays an important role in the treatment of patients suffering from acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) in order to prevent atherothrombotic events and restenosis or ischemic reocclusion, respectively. Moreover, stent implantation is often performed along with PCI to ensure that the arteries remain ...
Salminen Pirjo-Riitta PR Department of Heart Disease, Haukeland University Hospital, Bergen, Norway Department of Clinical Science, Faculty of Medicine and Dentistry, University of Bergen, Norway - - 2014
Experimental studies have demonstrated that insulin elicits cardioprotection in coronary occlusion-reperfusion models. We studied the effects of intracoronary insulin on regional cardiac function in a porcine model with reperfusion after a critical coronary artery stenosis. In 20 anaesthetized pigs with an extracorporeal shunt from the brachiocephalic to the left anterior ...
Lambadiari Vaia - - 2014
BackgroundThe interplay between the novel adipokine retinol-binding protein-4 (RBP4) and coronary artery disease (CAD) is still obscure. We investigated the relationship between RBP4 levels and the presence and severity of angiographically proven CAD and determined its possible role in acute myocardial infarction (AMI).Methods305 individuals with angiographically proven CAD (CAD-patients), were ...
Madhavan Mahesh V MV Department of Medicine, Division of Cardiology, New York-Presbyterian Hospital and the Columbia University Medical Center, New York, New - - 2014
Postprocedural anticoagulation (AC) after primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) may be administered for a number of specific therapeutic indications (e.g. atrial fibrillation or left ventricular thrombus). However, the safety and effectiveness of such post-PCI AC for specific indications are not well defined. Thus, we ...
Rischin Adam P AP Department of Cardiology, Frankston Hospital, Peninsula Health, Frankston, Victoria, Australia. Electronic address: - - 2014
We present the case of a 42 year-old woman admitted to hospital with ST-elevation myocardial infarction involving two separate coronary territories. Angiography revealed multi-embolic occlusions of her left anterior descending (LAD) and first obtuse marginal (OM1) coronary arteries. Transoesophageal echocardiogram (TOE) showed a lesion attached to the left cusp of ...
Di Lorenzo Emilio E Division of Cardiology, "S.G. Moscati", Avellino, - - 2014
The aim of the current study was to compare everolimus-eluting stents (EES) with sirolimus-eluting stents (SES) in patients undergoing primary angioplasty. Drug-eluting stents may offer benefits in terms of repeat revascularization. However, as shown for first-generation drug-eluting stents, they may be counterbalanced by a potential higher risk of stent thrombosis, ...
Abu-Laban Riyad B - - 2014
ABSTRACTExtracorporeal membrane oxygenation (ECMO) is a method to provide temporary cardiac and respiratory support to critically ill patients. In recent years, the role of ECMO in emergency departments (EDs) for select adults has increased. We present the dramatic case of a 29-year-old man who was placed on venoarterial ECMO for ...
Seadon Scott - - 2014
Clinical questionFollowing transient ischemic attack or acute minor stroke, does the combination of clopidogrel and aspirin reduce the risk of stroke greater than aspirin alone?Article chosenWang Y, Wang Y, Zhao X, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med 2013;369:11-9.ObjectiveThe primary ...
Kim Kun Il KI Department of Thoracic and Cardiovascular Surgery, Hallym University College of - - 2014
Myocardial infarction (MI) secondary to coronary artery fistula and the subsequent occlusion of the distal right coronary artery (RCA) after blunt chest trauma is a rare entity. Here, we describe a case of coronary artery fistula and occlusion with an inferior MI that occurred following blunt chest trauma. At the ...
Mazur M M Department of Anatomy, Jagiellonian University Medical College, Krakow, Poland. - - 2014
Invasive cardiac procedures, such as arrhythmia ablation, cardiac resynchronisation therapy, percutaneous mitral annuloplasty and retrograde cardioplegia delivery require cannulation of the coronary sinus (CS). Detailed knowledge of the CS ostium region, including recognition of the presence of the Thebesian valve which sometimes covers the sinus, is a key to successfully ...
Quintana Eduard E Division of Cardiovascular Surgery, Mayo Clinic College of Medicine, Rochester, Minn; Universitat de Barcelona, Barcelona, - - 2014
A proportion of patients experience a decrease in left ventricular (LV) ejection fraction (EF) after mitral valve repair; however, predictors and long-term consequences remain unclear. A study of 1705 patients with severe, degenerative mitral valve regurgitation and normal preoperative EF (>60%) undergoing mitral valve repair from 1993 to 2012 was ...
Stiermaier Thomas T Department of Internal Medicine - Cardiology, University of Leipzig - Heart Center, Leipzig, - - 2014
Despite intensive research efforts, the causative mechanisms of takotsubo cardiomyopathy (TC) are still unknown. Recently, morphologic characteristics of the left anterior descending coronary artery (LAD) have been proposed as a potential pathophysiological substrate. Hence, the aim of the present study was to evaluate the prevalence of myocardial bridging and LAD ...
Hoffmann Rainer R Department of Cardiology, Pneumology, Angiology and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany. Electronic address: - - 2014
Myocardial deformation analysis by speckle-tracking echocardiography (STE) has been used for analysis of myocardial viability and myocardial fibrosis. Patients with severe aortic stenosis are known to develop myocardial fibrosis. This study evaluated the association between myocardial fibrosis determined by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) and 2-dimensional STE ...
Song Pil Sang PS Division of Cardiology, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, South - - 2014
It is uncertain whether side branch predilatation before main vessel stenting is necessary. We evaluated the effect of side branch predilatation on outcomes in percutaneous coronary intervention for true nonleft main bifurcation determined by the Medina classification using the provisional approach. Target vessel failures (composite of cardiac death, myocardial infarction, ...
Nobre Christiane A - - 2014
Smoking is a risk factor for thromboangiitis obliterans (TAO, Buerger's disease) and arteriosclerosis, but there are few cases of coronary heart disease (CAD)-associated Buerger's disease. A literature search for articles in English, Spanish and French published between 1966 and 2012 on patients with coronary involvement and TAO revealed 12 patients. ...
Thomson Viji S VS Consultant Cardiologist, Department of Medicine, Sultan Qaboos University Hospital, Al Khoud, Muscat, PB: 35 PC: 123, Muscat, Sultanate of - - 2014
Multivessel coronary spasm resulting to cardiogenic shock and malignant ventricular arrhythmias though rare has been reported in the literature. The disease seems to be more prevalent in Asians. There have been isolated reports of coronary spasm in patients with reactive airway disease. We report the first case of spontaneous multivessel ...
Winter José Luis JL División de Enfermedades Cardiovasculares, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Servicio de Hemodinamia, Hospital Sótero del Río, Santiago - - 2014
Ticagrelor has been shown to improve outcomes in patients with ACS. However, the effects of this drug on parameters of microvascular flow in patients presenting with ST-segment elevation myocardial infarction (STEMI) have not been completely evaluated. Ninety-two patients presenting with STEMI where randomized to a loading dose of clopidogrel (600mg) ...
Fanari Zaher - - 2014
Myocardial injury from blunt chest trauma can result from either direct contusion or coronary artery injury due to acute coronary syndrome or coronary dissection. Although rare, blunt chest trauma is one of the non-atherosclerotic mechanisms leading to acute myocardial infarction (MI) in patients younger than 45 years. We are reporting ...
Acar Rezzan Deniz RD Department of Cardiology, Kartal Kosuyolu Education and Research Hospital, Istanbul, - - 2014
The aim of our study was to investigate the P-wave dispersion from standard electrocardiograms (ECGs) in patients with acute myocardial infarction (AMI) after cardiac rehabilitation (CR) and determine its relation to arterial stiffness. This is a prospective study included 33 patients with AMI and successfully re-vascularized by percutaneous coronary intervention ...
Sivalingam Sivakumar S Department of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, Malaysia - - 2014
A 9-year-old boy was referred with a perimembranous ventricular septal defect. At birth, he had undergone a right thoracotomy with ligation of a tracheoesophageal fistula, cervical esophagostomy, and feeding gastrostomy. At 2 years of age, he had gastric tube reconstruction with a pull-through retrosternally, anterior to the heart, and an ...
Lemesle Gilles G Hôpital Cardiologique, Centre Hospitalier Régional et Universitaire de Lille, Lille, France; Faculté de Médecine de Lille, Lille, France; INSERM UMR744, Institut Pasteur de Lille, Lille, France. Electronic address: - - 2014
The prevalence and correlates of dual-antiplatelet therapy (DAPT) use in stable coronary artery disease (CAD) are unknown. In addition, whether prolonged DAPT may impact prognosis in stable CAD has not been studied in real-life conditions. We studied 3,691 patients included in a prospective registry on stable CAD. The patients were ...
Bradley Steven M SM VA Eastern Colorado Health Care System, Denver, CO; University of Colorado School of Medicine at the Anschutz Medical Campus, Aurora, CO; Colorado Cardiovascular Outcomes Research Consortium, Denver, CO. Electronic address: - - 2014
Posttraumatic stress disorder (PTSD) is prevalent in the general population and US veterans in particular and is associated with an increased risk of developing coronary artery disease (CAD). We compared the patient characteristics and postprocedural outcomes of veterans with and without PTSD undergoing coronary angiography. This is a multicenter observational ...
Baker Nevin C NC Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, - - 2014
Patients presenting with ST-segment elevation myocardial infarction (STEMI) represent a high-risk group for in-hospital adverse events and bleeding. The safety and outcomes of eptifibatide in addition to bivalirudin in this population have not been determined. Over an 11-year period, we identified 1849 STEMI patients undergoing primary percutaneous coronary intervention (PCI), ...
Pilgrim Thomas T Department of Cardiology, Swiss Cardiovascular Center, University Hospital, Bern. Electronic address: - - 2014
Biodegradable polymers for release of antiproliferative drugs from metallic drug-eluting stents aim to improve long-term vascular healing and efficacy. We designed a large scale clinical trial to compare a novel thin strut, cobalt-chromium drug-eluting stent with silicon carbide-coating releasing sirolimus from a biodegradable polymer (O-SES, Orsiro; Biotronik, Bülach, Switzerland) with ...
Lee Chee-Hoon CH Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, - - 2014
As hypertrophied myocardium predisposes the patient to decreased tolerance to ischemia and increased reperfusion injury, myocardial protection is of utmost importance in patients undergoing aortic valve replacement (AVR) for severe aortic valve stenosis (AS). Consecutive 314 patients (mean age, 62.5±10.8 years; 143 females) with severe AS undergoing isolated AVR were ...
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