Search Results
Results 201 - 250 of 2339
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Bandosz Piotr P Department of Hypertension and Diabetology, Medical University in Gdansk, - - 2012
To examine how much of the observed rapid decrease in mortality from coronary heart disease in Poland after the political, social, and economic transformation in the early 1990s could be explained by the use of medical and surgical treatments and how much by changes in cardiovascular risk factors. A modelling ...
Biswas Shankar K SK Department of Radiology, Fujita Health University Hospital, Dengakugakubo, Kutsukake, Toyoake, Aichi, Japan. - - 2012
Following acute myocardial infarction (AMI) the area of myocardial perfusion and metabolism mismatch is designated as dysfunctional viable myocardium. (123)I-beta-methyl iodophenyl pentadecanoic acid (BMIPP) is clinically very useful for evaluating myocardial fatty acid metabolism, and (99)mTc-Tetrofosmin (TF) is a widely used tracer for myocardial perfusion. This study was designed to ...
Barker Lucy E LE From the St George's University Hospital, Tooting, London, United - - 2012
To report a case of bilateral ischemic optic neuropathy (ION) secondary to hypoperfusion of the optic nerve because of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, an uncommon condition causing stepwise subcortical small vessel infarcts because of arterial wall rigidity, loss of autoregulation, and hypoperfusion. We describe the ...
Huang Shao-Sung - - 2011
BACKGROUND: Thrombolysis in Myocardial Infarction (TIMI) score and Global Registry of Acute Coronary Events (GRACE) score have been validated as predictors of death in patients with acute myocardial infarction (AMI). This study was undertaken to determine whether the Sequential Organ Failure Assessment (SOFA) score had good accuracy for predicting mortality ...
Badran Hala Mahfouz - - 2011
AIMS: Hypertrophic cardiomyopathy (HCM) is usually associated with electrocardiographic (ECG) abnormalities. QT interval and its dispersion can be clinical markers of electrophysiological instability and ventricular arrhythmias. We aimed to clarify the relation of QT variables to mechanical dyssynchrony and myocardial function in HCM. METHODS AND RESULTS: The study population comprised ...
Carlsson M - - 2012
We aimed to quantify kinetic energy (KE) during the entire cardiac cycle of the left ventricle (LV) and right ventricle (RV) using four-dimensional phase-contrast magnetic resonance imaging (MRI). KE was quantified in healthy volunteers (n = 9) using an in-house developed software. Mean KE through the cardiac cycle of the ...
Das Sandeep R - - 2011
The aim of this study was to assess the impact of extreme (class III) obesity (body mass index [BMI] ≥40 kg/m(2)) on care and outcomes in patients with ST-segment elevation myocardial infarction (STEMI). Although its prevalence is increasing rapidly, little is known about the impact of extreme obesity on STEMI ...
Wei Gao - - 2011
Objectives:  To evaluate the association between N-terminal pro-B-type natriuretic peptide (NT-proBNP) values and the severity of coronary lesions at angiography in unstable angina patients with preserved left ventricular function. Methods:  A total of 133 patients with primary diagnosis of unstable angina were enrolled into this study. NT-proBNP level was determined ...
Bellsham-Revell Hannah R - - 2011
AIMS: To describe tissue Doppler time intervals and derived indices in hypoplastic left heart syndrome (HLHS) across surgical stages, taking account of age-related changes in the heart rate. Correlation of the myocardial performance index (MPI) and the systolic to diastolic (S:D) time ratio with other echocardiographic and magnetic resonance imaging ...
Masuda Masaharu - - 2011
Background: The effect of atrial fibrillation (AF) ablation on left atrial (LA) function has not been sufficiently determined. Methods: We enrolled 115 consecutive patients with paroxysmal or persistent AF that underwent AF ablation. Multidetector computed tomography was performed in sinus rhythm before and 3 months after ablation to evaluate LA ...
Brito João - - 2011
The SYNTAX score is a useful tool to evaluate percutaneous coronary intervention risk regarding the number, complexity, and location of lesions. Despite its proven value in the prognosis of three-vessel disease, there are few data about its usefulness in other selected subsets of patients. This study aimed to evaluate the ...
Schultz Jason J Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, MN 55455-0341, - - 2011
Sodium nitroprusside-enhanced CPR, or SNPeCPR, consists of active compression-decompression CPR with an impedance threshold device, abdominal compression, and intravenous sodium nitroprusside (SNP). We hypothesize that SNPeCPR will improve post resuscitation left ventricular function and neurological function compared to standard (S) CPR after 15 min of untreated ventricular fibrillation in a ...
Senni Michele - - 2011
BACKGROUND: Prognostic stratification in heart failure (HF) is crucial to guide clinical management and treatment decision-making. Currently available models to predict HF outcome have multiple limitations. We developed a simple risk stratification model, based on routinely available clinical information including comorbidities, the Cardiac and Comorbid Conditions HF (3C-HF) Score, to ...
Izumi Daisuke - - 2011
BACKGROUND: Previous studies showed that the interval between peak and end of the T wave (Tp-e) is a marker of transmural dispersion of ventricular repolarization. OBJECTIVE: We studied the relationship between a) the Tp-e on local pseudo transmural electrograms (pseudo transmural Tp-e) or limb leads of body surface ECG (surface ...
Motloch Lukas J - - 2011
BACKGROUND: Transcatheter aortic valve implantation (TAVI) represents an alternative option for elderly patients with severe aortic valve stenosis who are denied surgical aortic valve replacement (SAVR) because of high perioperative risk. The impact of TAVI on postprocedural atrial fibrillation is undefined. METHODS: In a single-center analysis, we assessed clinical data, ...
Yu Hsiu-Chin - - 2011
BACKGROUND: Atrial fibrillation is one of the most important causes of ischemic stroke. The purposes of this study were to recognize the incidence of ischemic stroke, the use of antithrombotic agents, the predictors of ischemic stroke, and prescription of warfarin during the three-years after atrial fibrillation was diagnosed. METHODS: This ...
Nakajima Kenichi - - 2011
Background: Cardiac event risk is estimated using quantitative gated myocardial perfusion imaging (MPI) and clinical background in patients with ischemic heart disease. The aim of the present study was to calculate major cardiac event risk and tabulate it in the Heart Risk Table for clinical use of risk stratification. Methods ...
Plischke Max - - 2011
Eur J Clin Invest 2011 ABSTRACT: Background  Recent studies show associations between inorganic phosphate and risk of heart failure in the general population as well as between fibroblast growth factor 23 (FGF-23) and outcome in coronary heart disease. This study was carried out to assess whether circulating levels of inorganic ...
Lai Hoang M - - 2011
BACKGROUND: An increasing coronary artery calcium score is associated with a higher likelihood of myocardial ischemia. HYPOTHESIS: The association of the coronary calcium score with myocardial ischemia in different coronary arteries needed to be investigated. METHODS: We correlated the coronary artery calcium (CAC) score with the severity of myocardial ischemia ...
Kato Tomoko Sugiyama - - 2011
Right ventricular failure (RVF) after left ventricular assist device (LVAD) placement is associated with increased morbidity and mortality. Echocardiography is a primary imaging method in the assessment of cardiac function; however, visualization of the right-sided heart is often technically difficult in patients with heart failure. We aimed to create a ...
Wong Raymond C - - 2011
Positron emission tomography (PET) imaging allows identification of stress-induced ischemia and myocardial viability in patients with ischemic cardiomyopathy. We assessed the left ventricular (LV) functional response to vasodilator stress in patients with advanced ischemic cardiomyopathy undergoing pharmacologic stress (PET) perfusion and metabolic imaging. Additionally, we aimed to determine if mitral ...
Kaza Elisabeth - - 2011
OBJECTIVE: The most common reason for late surgical reintervention after repair of complete atrioventricular canal defects is the development of left atrioventricular valve regurgitation. We sought to determine the changes in left atrioventricular valve geometry after surgical repair that may predispose to regurgitation. METHODS: Atrioventricular valve measurements were obtained by ...
Danad Ibrahim - - 2012
The incremental value of CAC over traditional risk factors to predict coronary vasodilator dysfunction and inherent myocardial blood flow (MBF) impairment is only scarcely documented (MBF). The aim of this study was therefore to evaluate the relationship between CAC content, hyperemic MBF, and coronary flow reserve (CFR) in patients undergoing ...
Estornell-Erill Jordi - - 2012
To evaluate the capability of multidetector computed tomography to diagnose the coronary etiology of left ventricular dysfunction compared with using invasive coronary angiography and magnetic resonance. Forty consecutive patients with left ventricular dysfunction of uncertain etiology underwent invasive coronary angiography and contrast magnetic resonance. All patients were evaluated with multidetector ...
Capodanno Davide - - 2011
The Evaluation of Xience Prime or Xience V versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization (EXCEL) trial is a multicenter, ongoing trial conducted in patients with left main disease and SYNTAX score≤32 to establish the presumptive advantage of percutaneous coronary intervention (PCI) versus bypass surgery in ...
Lown Mark T - - 2011
Risk assessment is central to the management of acute coronary syndromes. Often, however, assessment is not complete until the troponin concentration is available. Using 2 multicenter prospective observational studies (Evaluation of Methods and Management of Acute Coronary Events [EMMACE] 2, test cohort, 1,843 patients; and EMMACE-1, validation cohort, 550 patients) ...
Keller Pierre-Frederic - - 2011
Objectives:  To explore the diagnostic accuracies of anti-apolipoproteinA-1 (anti-ApoA-1) IgG and anti-phosphorylcholine (anti-PC) IgM alone, expressed as a ratio (anti-ApoA-1 IgG/anti-PC IgM), and combined with the TIMI score for non-ST-segment elevation myocardial infarction (NSTEMI) (NSTEMI-TIMI score) to create a new diagnostic algorithm - the Clinical Autoantibody Ratio (CABR) score - ...
Woods Kevin M - - 2011
Coronary computed tomography angiography (CTA) is an increasingly utilized, highly accurate noninvasive test for the diagnosis of coronary artery disease. Accumulating data have convincingly demonstrated that the presence, extent, and location of both obstructive and nonobstructive coronary atherosclerosis visualized on coronary CTA conveys powerful prognostic information, incremental to that provided ...
Hoke Robert S - - 2011
PURPOSE: To study the association between baseline heart rate and outcome in patients with multiple organ dysfunction (MODS) as well as the course of heart rate over the first 4 days during MODS. METHODS: Prospective observational study in 89 patients with MODS, defined as an APACHE-II score ≥20. Baseline heart rate ...
Villines Todd C - - 2011
OBJECTIVES: The purpose of this study was to describe the prevalence and severity of coronary artery disease (CAD) in relation to prognosis in symptomatic patients without coronary artery calcification (CAC) undergoing coronary computed tomography angiography (CCTA). BACKGROUND: The frequency and clinical relevance of CAD in patients without CAC are unclear. ...
Su Jianling - - 2011
OBJECTIVE: The aim of this study was to evaluate the additional predictive value of serum potassium (SK) to Thrombolysis In Myocardial Infarction (TIMI) risk score for malignant ventricular arrhythmias (MVA) in patients within 24 hours of acute myocardial infarction (AMI). METHODS: This was a 6-year retrospective study. The receiver operating ...
Stolen Craig M - - 2011
Biventricular pacing (BiV) has been shown to reduce wall stress and workload in regions near the pacing sites. This trial investigated if BiV near the ischemic region would reduce chest pain in patients with refractory angina due to severe coronary artery disease (CAD). Eleven patients were implanted with BiV devices ...
Hamrefors Viktor - - 2011
Objective:  To assess whether a genetic risk score that was previously shown to be associated with myocardial infarction and coronary artery disease is also associated with markers of carotid atherosclerosis. Design:  A total of 4022 middle-aged subjects from the general Swedish population were genotyped and individually assigned a genetic risk ...
Naya Masanao M Noninvasive Cardiovascular Imaging Program, Department of Medicine (Cardiology), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, - - 2011
The purpose of this study was to quantify the effects of coronary atherosclerosis morphology and extent on myocardial flow reserve (MFR). Although the relationship between coronary stenosis and myocardial perfusion is well established, little is known about the contribution of other anatomic descriptors of atherosclerosis burden to this relationship. We ...
Kim Song Soo - - 2011
To identify factors that can affect systolic compression of myocardial bridging (MB) of the mid-left anterior descending (LAD) coronary artery with dual-source computed tomography (DSCT). Patients with mid-LAD MB (n = 198) detected by DSCT were studied. MB was classified as incomplete superficial (IS), complete superficial (CS), and deep (D) type. The ...
Raman Vivek - - 2012
To conduct an economic analysis (EA) of coronary calcium scoring (CCS) using a 0 score, as alternative to stress electrocardiography (sECG) in diagnosing coronary artery disease (CAD). A decision tree was constructed to compare four strategies for investigation of suspected CAD previously assessed in the formulation of clinical guidelines for ...
Bailey Elizabeth A - - 2011
AIM: A voluntary audit was undertaken to compare left ventricular ejection fraction (LVEF) calculations from gated heart pool studies using software packages currently available throughout Australia and New Zealand (ANZ). METHODS: A data set previously developed by a task group of the Institute of Physics and Engineering in Medicine (IPEM) ...
Marcus Karen A - - 2012
Two-dimensional speckle tracking echocardiography (2DSTE) offers valuable information in the echocardiographic assessment of ventricular myocardial function. It enables the quantification and timing of systolic ventricular myocardial deformation. In addition, 2DSTE can be used to identify mechanical dyssynchrony, which is an important parameter in predicting the response to cardiac resynchronization therapy ...
Kimura Koichi - - 2011
Background: The subendocardial myocardium normally has higher systolic strain than the subepicardial myocardium and can be damaged first in face of ischemia. We investigated the reproducibility and feasibility of novel three-layer speckle tracking system and compared the diagnostic accuracy with experienced visual interpretation. Methods: An ameroid constrictor was placed around ...
Chang Anna Marie - - 2011
Academic Emergency Medicine 2011; 18:1065-1071 © 2011 by the Society for Academic Emergency Medicine ABSTRACT: Objectives:  Coronary angiography calcium score (CACS) is included for patients who receive coronary computed tomography angiography (CTA) as part of diagnostic testing for low-risk chest pain. Both tests add radiation exposure, and it is unclear ...
Farooq Vasim - - 2011
Percutaneous coronary intervention (PCI) of multivessel and/or left main stem disease have been shown to be potentially legitimate revascularization alternatives in appropriately selected patients. Risk stratification is an important component in guiding patients to identify the most appropriate revascularization modality (PCI or coronary artery bypass grafting [CABG]) in conjunction with ...
Park Seung-Jung - - 2011
Fragmented QRS (fQRS) on 12-lead electrocardiography reflects conduction delay caused by myocardial fibrosis and dysfunction. Ventricular fibrosis detected by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) is reportedly correlated with worse clinical outcomes in adults with repaired tetralogy of Fallot (TOF). The aim of this study was to assess ...
Girasis Chrysafios C Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Ba-583, 's Gravendijkwal 230, 3015 Rotterdam, The - - 2011
To investigate the ability of SYNTAX score and Clinical SYNTAX score (CSS) to predict very long-term outcomes in an all-comers population receiving drug-eluting stents. The SYNTAX score was retrospectively calculated in 848 patients enrolled in the SIRolimus-eluting stent compared with pacliTAXel-Eluting Stent for coronary revascularization (SIRTAX) trial. The CSS was ...
Ahlberg Alan W - - 2011
Although stress gated technetium-99m single-photon emission computed tomographic (SPECT) myocardial perfusion imaging (MPI) is useful in differentiating ischemic from nonischemic cardiomyopathy, its prognostic usefulness in this patient population is not well understood. Consecutive unique patients with suspected coronary artery disease who, for clinical indications, underwent technetium-99m rest and stress MPI ...
Wang Fang - - 2012
This study aimed to explore if the right ventricular outflow tract (RVOT) pacing is superior to right ventricular apical (RVA) pacing on the overall left ventricular (LV) function and regional wall motion. Sixty patients with atrio-ventricular (AV) block and normal ejection fraction undergoing dual-chamber pacemaker implantation were randomized to permanent ...
Liga Riccardo - - 2011
Multislice CT provides information on coronary luminal narrowing and on the structural abnormalities of the coronary arterial wall using densitometric analysis. We sought to investigate the effects of coronary luminal narrowing, structural abnormalities of the coronary arterial wall, and cardiovascular risk factors on regional and global myocardial blood flow (MBF) ...
Petretta Mario - - 2011
The aim of this study was to compare the prognostic value of coronary calcium scoring and coronary computed tomography (CT) angiography in assessing the cardiac risk and its temporal characteristics in patients at intermediate pre-test likelihood of coronary artery disease (CAD). Cardiac CT was performed in 326 patients at intermediate ...
Lux Robert L RL Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT 84112-5000, USA. - - 2011
Repolarization heterogeneity and rate dependency have long been established as factors contributing to arrhythmogenic risk. However, there are conflicting observations regarding the nature and extent of ventricular repolarization heterogeneity that complicate understanding of arrhythmogenic mechanisms. To explore these disparate findings, we studied ventricular repolarization heterogeneity and rate dependency in a ...
Arraiza M - - 2011
PURPOSE: To compare the accuracy of cardiac dual-source CT (DSCT) reconstructions obtained at 5% and 10% of the cardiac cycle and MRI for quantifying global left ventricular (LV) function and mass in heart transplant recipients. MATERIAL AND METHODS: We prospectively included 23 heart transplant recipients (21 male, mean age 60±11.7 ...
Davies Justin E JE MRCP, International Centre for Circulatory Health, St. Mary's Campus, Paddington, London, W2 1LA, UK. - - 2011
Aortic stenosis causes angina despite unobstructed arteries. Measurement of conventional coronary hemodynamic parameters in patients undergoing valvular surgery has failed to explain these symptoms. With the advent of percutaneous aortic valve replacement (PAVR) and developments in coronary pulse wave analysis, it is now possible to instantaneously abolish the valvular stenosis ...
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