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Rognoni Andrea - - 2012
In a variant proportion of patients presenting with chest pain and electrocardiographic changes charactheristic for ST - elevation myocardial infarction, percutaneous coronary intervention achieve epicardial coronary artery reperfusion but not myocardial reperfusion (ranging from 5% to 50%); furthermore, prolonged myocardial ischemia often breaks down the coronary microvasculature and the flow ...
Tota-Maharaj Rajesh - - 2012
Although coronary artery calcium (CAC) scoring has an established role in risk-stratifying asymptomatic patients at intermediate risk of coronary heart disease (CHD), its utility in the evaluation of patients with chest pain is uncertain. We conducted a literature review of articles investigating the utility of: (1) CAC scoring in elective ...
Marshall Andrew - - 2012
To assess the prognostic value of cardiac iodine-123 metaiodobenzylguanidine ((123)I-MIBG) scintigraphy to predict ventricular arrhythmias in patients with heart failure (HF) listed for implantable cardioverter-defibrillator (ICD) devices as primary prevention. A prospective cohort study in 27 patients with HF referred for ICD implantation (alone or in combination with cardiac resynchronisation ...
Groner Abraham - - 2012
Introduction The prevalence of right ventricular dysfunction in idiopathic dilated cardiomyopathy is incompletely studied in children. Furthermore, right ventricular function may signal worse outcomes. We evaluated recently published right ventricular function echocardiographic indices in identifying dysfunction in children with idiopathic dilated cardiomyopathy and the impact of right ventricular dysfunction on ...
Providência R - - 2012
We have read with interest the article by Róldan and colleagues [1] demonstrating that high sensitivity troponin T and interleukin-6 were significantly associated with prognosis (both all cause mortality and adverse cardiovascular events) in patients with atrial fibrillation (AF), even after adjusting for CHADS(2) score. Therefore, the authors have proposed ...
Duan Wen-Hui - - 2012
OBJECTIVE: To evaluate the clinical effects of Chinese medicine (CM) on acute myocardial infarction (AMI) with a prospective cohort study. METHODS: A total of 334 AMI patients from January 2007 to March 2009 were consecutively enrolled, and were assigned to a treatment group (169 cases) treated with combined therapy (CM ...
Nanasato Mamoru - - 2012
Background: Whether or not automated scores obtained from myocardial single-photon emission computed tomography (SPECT) imaging using software correlate with the visual interpretations by experts remains obscure. Methods and Results: Eighty-seven consecutive patients with known or suspected angina pectoris underwent <sup>201</sup>thallium stress/rest SPECT followed by coronary angiography and the summed difference scores (SDS) ...
Yoda Shunichi - - 2012
BACKGROUND: Cardiovascular disease is the leading cause of death among patients with chronic kidney disease (CKD). Therefore, stratification of the prognostic risk of cardiovascular events is useful for their clinical management. We evaluated the ability of electrocardiogram (ECG)-gated myocardial perfusion single photon emission computed tomography (SPECT) to predict cardiac events ...
Tanaka Tetsuya - - 2012
In 2005, the SYNTAX score was reported as "an angiographic tool grading the complexity of coronary artery disease". We investigated risk factors for the complexity of coronary artery disease (CAD) using SYNTAX scores in patients with new-onset CAD. The subjects were 359 consecutive cases that underwent de novo percutaneous coronary ...
Grant Andrew D M - - 2012
This study sought to determine the utility of quantitation of right ventricular (RV) function in predicting RV failure in patients undergoing left ventricular assist device (LVAD) implantation. Clinical evaluation alone seems insufficient for predicting RV failure, an important cause of morbidity and mortality after LVAD implantation. Clinical, hemodynamic, and echocardiographic ...
Shaikh Ayaz Hussain - - 2012
The case of a 55 years old, hypertensive, obese female is presented, who came to the emergency department with inferoposterior ST segment elevation myocardial infarction (STEMI) with right ventricular infarction. After thrombolytic therapy, she reperfused but had anginal symptoms on minimal activity. The patient underwent coronary angiogram which showed aneurysmal ...
Kyriacou Andreas A International Centre for Circulatory Health, St. Mary's Hospital and Imperial College, 59-61 North Wharf Road, W2 1LA, United Kingdom. - - 2012
Normal coronary blood flow is principally determined by a backward-traveling decompression (suction) wave in diastole. Dyssynchronous chronic heart failure may attenuate suction, because regional relaxation and contraction overlap in timing. We hypothesized that biventricular pacing, by restoring left ventricular (LV) synchronization and improving LV relaxation, might increase this suction wave, ...
Ferencik Maros M Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. - - 2012
The objective was to determine the association of four clinical risk scores and coronary plaque burden as detected by computed tomography (CT) with the outcome of acute coronary syndrome (ACS) in patients with acute chest pain. The hypothesis was that the combination of risk scores and plaque burden improved the ...
Moral Sergio - - 2012
INTRODUCTION AND OBJECTIVES: Quantification of myocardial area-at-risk after acute myocardial infarction has major clinical implications and can be determined by cardiovascular magnetic resonance. The Bypass Angioplasty Revascularization Investigation Myocardial Jeopardy Index (BARI) and Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) angiographic scores have been widely used ...
Cha Kyoung Chul - - 2012
ObjectivesThis study was conducted to determine the proper hand position on the sternum for external chest compression to generate a maximal haemodynamic effect during cardiopulmonary resuscitation (CPR).Methods114 patients with cardiac arrest who underwent chest CT after successful resuscitation from January 2006 to August 2009 were included in the study. To ...
Spiewak Mateusz - - 2012
BACKGROUND: Previous studies have advocated quantifying pulmonary regurgitation (PR) by using PR volume (PRV) instead of commonly used PR fraction (PRF). However, physicians are not familiar with the use of PRV in clinical practice. The ratio of right ventricle (RV) volume to left ventricle volume (RV/LV) may better reflect the ...
Oldridge Neil - - 2012
Background: Evaluation of health-related quality of life (HRQL) is important in improving the quality of patient care.Methods: The HeartQoL Project, with cross-sectional and longitudinal phases, was designed to develop a core ischemic heart disease (IHD) specific HRQL questionnaire, to be called the HeartQoL, for patients with angina, myocardial infarction (MI), ...
Chenoune Y - - 2012
Automated extraction of quantitative parameters from Cardiac Magnetic Resonance Images (CMRI) is crucial for the management of patients with myocardial infarct. This work proposes a post-processing procedure to jointly analyze Cine and Delayed-Enhanced (DE) acquisitions, in order to provide an automatic quantification of myocardial contraction and enhancement parameters and a ...
Jogiya Roy R King's College, London, - - 2012
The goal of this study was to determine the diagnostic accuracy of dynamic 3-dimensional (3D) whole heart myocardial perfusion cardiovascular magnetic resonance (CMR) against invasively determined fractional flow reserve (FFR) and to establish the correlation between myocardium at risk defined by using the invasive Duke Jeopardy Score (DJS) and noninvasive ...
Defilippi Christopher - - 2012
BACKGROUND:Quantification and comparison of high-sensitivity (hs) cardiac troponin I (cTnI) and cTnT concentrations in chronic kidney disease (CKD) have not been reported. We examined the associations between hs cTnI and cTnT, cardiovascular disease, and renal function in outpatients with stable CKD.METHODS:Outpatients (n = 148; 16.9% with prior myocardial infarction or ...
Nakata Tomoaki - - 2012
Quantitative SPECT analysis contributes to the diagnostic and prognostic assessment of coronary artery disease. A novel automated scoring system (heart score view) can provide identical quantitative information to that determined by expert visual analysis. The aim of the present study is to evaluate the prognostic value of the automated SPECT ...
Yamamoto Yasushi - - 2012
The degree of myocardial technetium-(99m)-pyrophosphate ((99m)Tc-PYP) accumulation in cardiac amyloidosis is conventionally evaluated by the PYP score. This method involves qualitative visual evaluation on two-dimensional images. Here, we performed three-dimensional quantitative analysis using software developed in our laboratory. We performed dual myocardial imaging using thallium-(201)-chloride ((201)Tl-Cl) and (99m)Tc-PYP in cases ...
Gupta Sachin S Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, 75390-9047, - - 2013
Left atrial (LA) structural and functional abnormalities may be subclinical phenotypes, which identify individuals at increased risk of adverse outcomes. Maximum LA volume (LAmax) and LA emptying fraction (LAEF) were measured via cardiac magnetic resonance imaging in 1802 participants in the Dallas Heart Study. The associations of LAEF and LAmax ...
Georgiopoulou Vasiliki V - - 2012
The heart failure epidemic calls for urgent prevention efforts. Hypertension is present in the majority of individuals who develop heart failure and carries the highest population-attributable risk for heart failure together with coronary heart disease. Therefore, hypertension is a natural prime target for prevention interventions. However, a substantial proportion of ...
Ndrepepa Gjin - - 2012
BACKGROUND: The impact of coronary atherosclerotic burden on prognosis and presentation of patients with coronary artery disease (CAD) is unknown. We investigated the association of coronary atherosclerotic burden with clinical outcome and presentation as unstable angina in patients with CAD. METHODS: This study included 10,647 patients with stable (n = 8,149) and ...
Choi Eui-Young - - 2012
Systemic inflammation has been linked to the development of heart failure in population studies including Multi-Ethnic Study of Atherosclerosis (MESA), but little evidence exists regarding potential mechanism of this relationship. In this study, we used longitudinal magnetic resonance imaging follow-up analysis to examine whether C-reactive protein (CRP) levels relate to ...
Williams Richard V RV University of Utah, Salt Lake City, Utah 84113, USA. - - 2013
Although many Fontan patients undergo pacemaker placement, there are few studies characterizing this population. Our purpose was to compare clinical characteristics, functional status and measures of ventricular performance in Fontan patients with and without a pacemaker. The National Heart, Lung, and Blood Institute funded Pediatric Heart Network Fontan Cross-Sectional Study ...
Lee Chee-Siong - - 2012
BACKGROUND: It is traditionally difficult to estimate left ventricular (LV) systolic function in atrial fibrillation (AF). The aim of this study was to validate the use of an index beat, the beat after the nearly equal preceding (RR1) and pre-preceding (RR2) intervals, for the measurement of LV peak longitudinal systolic ...
Zhao Sheng - - 2012
This study was undertaken to evaluate the right ventricular myocardial systolic function and its relation to the fetal volume and pressure overload in recipient twin of twin to twin transfusion syndrome with speckle tracking echocardiography. Longitudinal peak systolic strains of the right ventricle were measured by speckle tracking echocardiography in ...
Gordon Sonya G - - 2012
Objective-To determine the effect of PO administration of pimobendan on clinical and echocardiographic variables and survival time in cats with heart failure characterized by ventricular systolic dysfunction. Design-Retrospective cohort study. Animals-27 client-owned cats (16 male and 11 female) with heart failure, treated with pimobendan (mean ± SD dosage, 0.26 ± ...
Wu Jian - - 2012
Objectives- Animal models of myocardial infarction (MI) are widely used not only in analyses of the mechanisms but also in testing the efficacy of therapeutic strategies for the disease. It is therefore critically important but almost impossible to exactly evaluate the validity of coronary artery ligation in a mouse model ...
Ozturk C - - 2012
Ventricular assist device (VAD) application has become an increasingly common method to treatment end-stage heart failure. In this study we evaluated the effect of VAD implantation upon the quality of life among Turkish patients with end-stage heart failure. Twenty-eight VAD implantation patients included 3 (10.7%) with biventricular support using the ...
Jim Man Hong - - 2012
Introduction: A few electrocardiographic criteria have been described to identify the infarct-related artery in inferior myocardial infarction. The aim of this study was to devise an arithmetic score to further improve the diagnostic accuracy. Materials and Methods: From 2004 to 2006, 78 patients who underwent primary angioplasty for inferior myocardial ...
Altintas Nejat - - 2012
Obstructive sleep apnea (OSA) causes increased cardiovascular morbidity and mortality, including systemic arterial hypertension, coronary heart disease, heart rhythm and conduction disorders, heart failure and stroke. In our study, we aimed to assess left ventricular mass and myocardial performance index (MPI) in OSA patients. A cross-sectional study conducted between May ...
Chieffo Alaide A Department of Cardio-Thoracic and Vascular Diseases, San Raffaele Scientific Institute, Via Olgettina 60, Milan, - - 2012
The aim of this study was to compare, in a large all-comers registry, major adverse cardiac and cerebrovascular events (MACCE) after percutaneous coronary intervention (PCI) with first-generation drug-eluting stents (DES) versus coronary artery bypass grafting (CABG) in unprotected left main coronary artery (ULMCA) stenosis. Percutaneous coronary intervention with DES implantation ...
Moussouttas Michael - - 2012
Anterior cerebral artery (ACA) ischemia may be underdiagnosed following subarachnoid hemorrhage (SAH). The purpose of this study is to characterize the prevalence, timing, and risk factors for ACA infarction, following primary spontaneous SAH. This was a retrospective study of consecutive SAH patients. Final admission CT scans were reviewed for the ...
Woolf Kevin J - - 2012
The optimal approach to encourage smoking cessation after acute coronary syndrome (ACS) remains unclear. The safety of nicotine replacement therapy (NRT) after ACS is not well established. The aim of the present study was to determine the relationship between NRT use and adverse cardiovascular outcomes after ACS. Using a pre-existing ...
Gorur Gozde Daglioz - - 2012
OBJECTIVE: A mild decrease in blood pressure and increase in heart rate (HR) are considered normal hemodynamic responses to dipyridamole. In this study, we tried to investigate HR response to dipyridamole and its predictors in patients undergoing gated myocardial perfusion single photon emission computed tomography (SPECT). METHODS: 201 consecutive patients ...
Shiomi Hiroki - - 2012
The long-term outcome of percutaneous coronary intervention (PCI) compared to coronary artery bypass grafting (CABG) for unprotected left main coronary artery disease (ULMCAD) remains to be investigated. We identified 1,005 patients with ULMCAD of 15,939 patients with first coronary revascularization enrolled in the CREDO-Kyoto PCI/CABG Registry Cohort-2. Cumulative 3-year incidence ...
Kelly Anne-Maree - - 2012
AIM: Acute coronary syndrome (ACS) is a common life-threatening condition but the majority of patients are at low risk of acute adverse events. In 2005, the GRACE Freedom-from-Event score (GFFES) was developed to identify patients with a low risk of adverse in-hospital events. Our aim was to externally validate this ...
Park Dae-Gyun - - 2012
BACKGROUND: Hypertensive cardiomyopathy with reduced ejection fraction (HTCMREF) is known as an important cause of reversible cardiomyopathy, but its serial changes on echocardiography is yet to be elucidated. HYPOTHESIS: HTCMREF on serial echocardiography has distinctive points as compared to idiopathic dilated cardiomyopathy (idDCM). METHODS: We retrospectively studied 18 hypertensive patients ...
Scruth Elizabeth Ann - - 2012
BACKGROUND: Accurate risk stratification is important in the management of acute coronary syndrome (ACS) patients. Several risk scores have been developed to stratify patients hospitalized with ACS. AIM: To compare the prognostic value of three risk scores used to determine the risk for secondary events in patients diagnosed with ST-elevation ...
Kristiansen H M - - 2012
AIMS: To investigate the influence of left ventricular (LV) lead position on LV dyssynchrony in cardiac resynchronization therapy (CRT). METHODS AND RESULTS: The LV lead was prospectively targeted to the latest activated LV segment (concordant) evaluated by two-dimensional speckle tracking radial strain (ST-RS) echocardiography in 103 CRT recipients (67 ± ...
Tigges Stefan - - 2012
Accurate coronary artery calcium scoring improves risk stratification in some strata of the population. We evaluated individual and combined effects of reader experience, heart rate, vessel displacement, and trajectory on computed tomography (CT) Agatston score, calcium volume, and calcium mass in a cardiac phantom model. A cardiac motion phantom was ...
Viana Fabiano F - - 2012
OBJECTIVES: A single or dual-dose strategy for myocardial protection is attractive in long operations, in avoiding the need to interrupt the procedure to re-administer cardioplegia. We hypothesized that a single administration of Bretschneider histidine-tryptophan-ketoglutarate (HTK) crystalloid solution (Custodiol) offers myocardial protection comparable with repeated tepid blood cardioplegia. METHODS: We reviewed ...
Barold S S - - 2012
This report describes a new cause of desynchronization encountered in a cardiac resynchronization device functioning in the VVIR mode. Left ventricular stimulation was inhibited when the sensor-driven rate exceeded the programmed upper tracking rate. With these devices, it is important to program the maximum tracking interval (essentially equivalent to a ...
- - 2012
The following articles are being highlighted as part of Circulation: Arrhythmia and Electrophysiology's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation: Arrhythmia and Electrophysiology, Circulation, and the other Circulation subspecialty journals. The studies included in this article represent the ...
Fukuda Yamato - - 2012
BACKGROUND: E/e' and s' are thought to reflect left ventricular diastolic and systolic function, respectively. However, there are no reports on the combined use of E/e' and s' in predicting the outcome in acute myocardial infarction (AMI). METHODS: For 20 months beginning in October 2006, we enrolled 65 AMI patients who ...
Motwani Manish - - 2012
BACKGROUND: Although left ventricular hypertrophy (LVH) in Fabry disease (FD) can improve with enzyme-replacement therapy (ERT), the response is difficult to predict. Furthermore, the response of other cardiac features such as aortic dilatation and ECG changes are poorly understood. METHODS: A local registry of 66 patients with FD was studied. ...
Putaala J - - 2012
AIM: To determine the functional outcome in a cohort of young adults with ischemic stroke patients, focusing on components of lipid profile. METHODS: In our registry including consecutive patients with first-ever ischemic stroke aged 15-49 from 1994 to 2007, we analyzed predictors of 3-month functional outcome (modified Rankin Scale, mRS). ...
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