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Ritchie Rebecca H - - 2009
Left ventricular hypertrophy (LVH), an increased left ventricular (LV) mass, is common to many cardiovascular disorders, initially developing as an adaptive response to maintain myocardial function. In the longer term, this LV remodelling becomes maladaptive, with progressive decline in LV contractility and diastolic function. Indeed LVH is recognised as an ...
Bacharova Ljuba - - 2010
The increased QRS voltage is considered to be a specific electrocardiogram (ECG) sign of left ventricular hypertrophy (LVH), and it is expected that the QRS voltage reflects the increase in left ventricular mass (LVM). However, the increased QRS voltage is only one of QRS patterns observed in patients with LVH. ...
Yasuno Shinji - - 2009
OBJECTIVE: To evaluate the associations of left ventricular hypertrophy (LVH) and its changes with the incidence of cardiovascular events and the time-course of serum creatinine (sCr) levels in high-risk hypertensive patients who participated in the Candesartan Antihypertensive Survival Evaluation in Japan trial. METHODS: We analysed data of 1447 patients who ...
Nadour Wadih - - 2009
Left ventricular hypertrophy (LVH) has been demonstrated to define an adverse cardiovascular prognosis. However, due to poor noninvasive tools in which to accurately define LVH, the clinical manifestations dictate an inexact manner in which to either initiate therapy or to gauge the success of LVH regression. Herein, the authors define ...
Lunde Søren - - 2009
OBJECTIVE: To develop a porcine model for Left Ventricular Hypertrophy (LVH) in which cardiac performance could be quantified non-invasively by Doppler ultrasound. DESIGN: Sixteen 5 kg piglets were divided into two groups. In the first group (n=12) we performed an aortic banding and in the second group (n=4) a sham-operation. ...
Nah Jong Chun - - 2009
In the absence of hypertension, hypertrophic cardiomyopathy is the most common cause of left ventricular hypertrophy (LVH). However, it has been reported that up to 3% of males with unexplained LVH have Fabry disease, an X-linked disorder of glycophospholipid metabolism that is due to a deficiency in the lysosomal enzyme ...
Jameel Mohammad N - - 2009
The heart carries out its pumping function by converting the chemical energy stored in fatty acids and glucose into the mechanical energy of actin-myosin interaction of myofibrils. Development of congestive heart failure is usually preceded by a period of compensated left ventricular hypertrophy (LVH) and alterations in myocardial bioenergetics have ...
Estes E Harvey EH - - 2009
The electrocardiographic diagnosis of left ventricular hypertrophy (LVH) has been centered on improving the diagnostic sensitivity and specificity of the method, using criteria whose precise relationship to increased left ventricular mass are not established. Although the electrocardiogram (ECG) has been displaced to a secondary role in the prediction of left ...
Bacharova Ljuba - - 2009
The problem of discrepancies between left ventricular mass (LVM) and electrocardiography (ECG) findings in diagnosis of left ventricular hypertrophy (LVH) is approached from the perspective of the diagnostic ability of ECG. Contrary to current clinical understanding of LVH as an increase in LVM, the LVH is defined as the organ ...
Mohan Shilpi - - 2009
AIM: We report an unusual case of previously healthy post partum woman who had presented with congestive cardiac failure. She had no significant past history. METHOD: She underwent cardiac evaluation. Echo showed severe left ventricular dysfunction and multiple mobile masses in the left ventricle. Cardiac MRI was done to assess ...
Stanton Tony - - 2009
OBJECTIVES: The aim of this study was to investigate the relative contributions of left ventricular hypertrophy (LVH) and myocardial ischemia to the association between abnormal myocardial deformation during dobutamine stress echocardiography (DSE) and mortality. BACKGROUND: Both left ventricular hypertrophy (LVH) and myocardial ischemia are known to convey a significant adverse ...
Newell-Fugate A - - 2009
A 9-year-old apparently healthy male African wild dog (Lycaon pictus) was found dead in its enclosure at the De Wildt Cheetah and Wildlife Centre. Necropsy revealed a pericardium distended by approximately 250 ml of thick blood. A soft, red, lobulated mass was attached to the periaortic fat between the level ...
Masaidi Meilikemu - - 2009
AIM: Whether retinal microvascular disease is associated with markers of cardiac and extracardiac organ damage in human hypertension is still unclear. We examined the relationship between retinal arteriolar-venular ratio (AVR) and left ventricular hypertrophy, carotid atherosclerosis and microalbuminuria in essential hypertension. METHODS: A total of 386 untreated and treated uncomplicated ...
Budoff Matthew J - - 2009
RATIONALE AND OBJECTIVES: Left ventricular hypertrophy (LVH) is associated with an increased risk of cardiac death. The present study evaluates whether using computed tomographic (CT)-derived criteria for normal myocardial mass can improve detection of LVH on CT angiography (CTA). MATERIALS AND METHODS: A total of 2238 subjects (63 +/- 9 ...
Völzke Henry - - 2009
BACKGROUND: There are considerable regional disparities in the prevalence of cardiovascular risk factors within Germany. We undertook this study to investigate differences in the prevalence of left ventricular hypertrophy (LVH) between northeast and southwest Germany. METHODS: Data from two population-based studies, Kooperative Gesundheitsforschung im Raum Augsburg (KORA) conducted in southwest ...
Maffei Erica - - 2009
We present a case of a 46-year-old woman who presented to our institution with a history of quadrantectomy and a current progressive dyspnea. Multislice computed tomography of the heart and coronary arteries was performed with standard protocol. The investigation demonstrated a hypodense mass infiltrating the interventricular septum, the cardiac apex ...
Leoncini Giovanna - - 2009
OBJECTIVE: The relationship between mild reduction in renal function and cardiac structure and function have not yet been fully elucidated. We investigated cardiac and renal abnormalities in 400 untreated, nondiabetic patients (65% men, mean age 47 years) with primary hypertension and normal serum creatinine. METHODS: Renal abnormalities were defined as ...
Plana Juan Carlos - - 2009
Echocardiography is the most common noninvasive tool used in assessing cardiac masses. Real-time three-dimensional echocardiography expands the diagnostic capabilities of cardiac ultrasound in assessing the location, composition, size, and relationship to other structures of cardiac masses. The improved characterization of the anatomy of the mass, in conjunction with the accurate ...
Chopra H K - - 2009
AIMS & OBJECTIVE: To evaluate the impact of the Metabolic Syndrome (MetS) on various echo variables by 3D Echocardiography. 100 patients of MetS from indoor and outdoor patient departments were subjected to Echocardiographic and Carotid Doppler evaluation. They were divided into three groups: Group A, Group B and Group C ...
Bacharova Ljuba - - 2009
Electrocardiographic signs of left ventricular hypertrophy (LVH) are on one hand accepted as independent cardiovascular risk factors and indicators of target organ damage in hypertensive patients, but, on the other hand they are strongly criticized for their low sensitivity. In this paper, a historic perspective on the ECG diagnosis of ...
Díez Javier - - 2009
A new pathophysiologic paradigm on HHD is emerging. This entity is the result of the pathologic structural remodeling of the myocardium in response to a mosaic of hemodynamic and nonhemodynamic factors altered in hypertension more than just the adaptive hypertrophy of the left ventricular wall to increased pressure. The potential ...
Buck P C - - 2009
Angiotensin-converting enzyme (ACE) activity and polymorphism contribute significantly to the prognosis of patients with cardiomyopathy. The aim of this study was to determine the activity and type of ACE polymorphism in patients with familial and nonfamilial hypertrophic cardiomyopathy (HCM) and to correlate these with echocardiographic measurements (echo-Doppler). We studied 136 ...
Baks Timo - - 2011
We describe a patient with left sided congestive heart failure and a round-shaped mass on the chest X-ray. Using computed tomography, the mass is diagnosed as a phantom tumour consisting of loculated effusion in the interlobular fissure that vanishes after treatment for heart failure is initiated.
Rinaldi C - - 2009
Left ventricular hypertrophy (LVH) is a frequent finding in Friedreich's ataxia (FRDA). In previous studies treatment with idebenone, a synthetic analogue of coenzyme Q10, has been associated with a substantial decrease in myocardial hypertrophy, despite great variability in cardiac responsiveness among patients. Here we present the results of a retrospective ...
Palecek Tomas - - 2010
Left ventricular (LV) hypertrophy is the hallmark of cardiac involvement in Fabry disease (FD). However, its pathogenesis is not clearly understood as pathologic substrate accumulation represents only 1-2% of the total cardiac mass. Abnormal myocardial energy metabolism has been previously demonstrated in different forms of cardiomyopathies. We hypothesized that myocardial ...
Reffelmann Thorsten - - 2009
OBJECTIVE: We assessed whether the relationship between electrocardiographic and echocardiographic information on left ventricular hypertrophy predicts the development of left ventricular mass over 5 years. METHODS: Linear regression analyses between various electrocardiographic indices of left ventricular hypertrophy and left ventricular mass (echocardiography) indexed to height2.7 (LVMI(ht)) was performed in 1488 ...
Liu Yingheng - - 2009
Patients with hypothyroidism are at a higher risk for coronary vascular disease. Patients with diabetes and related vascular complications also have an increased incidence of low thyroid function. While thyroid hormones (THs) may be key regulators of a healthy vasculature, potential undesirable side effects hinder their use in the treatment ...
Lee Hae-Yeoun - - 2010
An automatic left ventricle (LV) segmentation algorithm is presented for quantification of cardiac output and myocardial mass in clinical practice. The LV endocardium is first segmented using region growth with iterative thresholding by detecting the effusion into the surrounding myocardium and tissues. Then the epicardium is extracted using the active ...
Gao Jing - - 2009
Obstructive sleep apnea syndrome (OSAS) may predispose patients to congestive heart failure, suggesting a deleterious effect of OSAS on myocardial contractility. We investigated whether essential hypertensive individuals with OSAS are characterized by decreased right and left ventricular myocardial performance. Our study population consisted of 45 consecutive patients with newly diagnosed ...
Van Hee Victor C - - 2009
Ambient air pollution has been associated with heart failure morbidity and mortality. The mechanisms responsible for these associations are unknown but may include the effects of traffic-related pollutants on vascular or autonomic function. We assessed the cross-sectional relation between long-term air pollution, traffic exposures, and important end-organ measures of alterations ...
Ak Koray - - 2009
Right heart infective endocarditis presenting as an isolated apical mural mass is an extremely uncommon finding. A 24-year-old woman with congenital deafness and aphasia was admitted with recurrent attacks of fever and lobar pneumonia. Her past medical history was significant for an open operation for left nephrolithiasis five months before ...
Rudolph Andre - - 2009
OBJECTIVES: We aimed to evaluate the incidence and patterns of late gadolinium enhancement (LGE) in different forms of left ventricular hypertrophy (LVH) and to determine their relation to severity of left ventricular (LV) remodeling. BACKGROUND: Left ventricular hypertrophy is an independent predictor of cardiac mortality. The relationship between LVH and ...
Abramov Dmitry - - 2010
BACKGROUND: Accurate assessment of left ventricular hypertrophy (LVH) and ventricular geometry is important, especially in patients with heart failure (HF). The aim of this study was to compare the assessment of ventricular size and geometry by 2D and 3D echocardiography in normotensive controls and among HF patients with a normal ...
Buchner Stefan - - 2009
BACKGROUND: Left ventricular hypertrophy (LVH) is a hallmark of chronic pressure or volume overload of the left ventricle and is associated with risk of cardiovascular morbidity and mortality. The purpose was to evaluate different electrocardiographic criteria for LVH as determined by cardiovascular magnetic resonance (CMR). Additionally, the effects of concentric ...
Buechel Emanuela Valsangiacomo - - 2009
BACKGROUND: Quantification of ventricular volume by steady state free precession (SSFP) cardiovascular magnetic resonance is accurate and reproducible. Normal values exist for adults, but are lacking for children.We sought to establish normal values for left and right ventricular volumes, mass and function in healthy children by using SSFP. METHODS AND ...
Fornal M - - 2009
The relationship between erythrocyte deformability and aggregability with left ventricular mass index has been examined in patients diagnosed with at least one cardiovascular risk factor but without ongoing coronary heart disease. The group consisted of 66 individuals, 30 men and 36 women, of the average age 57.7 years. For each ...
Rider Oliver J - - 2009
BACKGROUND: Obesity is linked to increased left ventricular mass, an independent predictor of mortality. As a result of this, understanding the determinants of left ventricular mass in the setting of obesity has both therapeutic and prognostic implications. Using cardiovascular magnetic resonance our goal was to elucidate the main predictors of ...
Kozhevnikov D - - 2009
BACKGROUND: The coexistence of cardiac hypertrophy (H) and ischemia (I) can create a particularly arrhythmogenic substrate. Most studies investigate the effects of global I on H. However, global I is not a good surrogate model of the clinical situation. OBJECTIVE: The purpose of this study was to investigate the electrophysiological ...
Kohler James J - - 2009
Mitochondrial toxicity results from pyrimidine nucleoside reverse transcriptase inhibitors (NRTIs) for HIV/AIDS. In the heart, this can deplete mitochondrial (mt) DNA and cause cardiac dysfunction (eg, left ventricle hypertrophy, LVH). Four unique transgenic, cardiac-targeted overexpressors (TGs) were generated to determine their individual impact on native mitochondrial biogenesis and effects of ...
Barrabés José A - - 2009
Left ventricular hypertrophy (LVH) portends a worse outcome after non-ST-elevation acute myocardial infarction (NSTEMI). However, its definition has varied and the incremental prognostic information provided by echocardiography has been unclear. Different electrocardiographic and echocardiographic criteria for LVH were compared for their ability to predict in-hospital complications in 451 consecutive patients ...
Yu Jeong J - - 2009
Our aim was to determine whether the index of left ventricular mass increases during the acute and subacute phase of Kawasaki disease, and to investigate any relationship between this index and clinical and echocardiographic variables. We performed, therefore, a retrospective study of 66 children with Kawasaki disease, having a mean ...
Schuleri Karl H - - 2008
Porcine models have become increasingly popular in cardiovascular research. The standard farm pig rapidly increases in body weight and size, potentially confounding serial measurements of cardiac function and morphology. We developed an adult porcine model that does not show physiologic increases in heart mass during the study period and is ...
Lee Hae-Yeoun - - 2008
To develop and evaluate an automated left ventricle (LV) segmentation algorithm using Graph searching based on Intensity and Gradient information and A priori knowledge (lvGIGA). The lvGIGA algorithm was implemented with coil sensitivity correction and polar coordinate transformation. Graph searching and expansion were applied for extracting myocardial endocardial and epicardial ...
Raichlin Eugenia - - 2008
BACKGROUND: Left ventricular hypertrophy (LVH) and diastolic dysfunction occur after cardiac transplantation. We investigated sirolimus (SRL) as primary immunosuppression for the attenuation of LVH and diastolic dysfunction of the cardiac allograft. METHODS: Seventy cardiac transplant recipients were converted to SRL, 5.79+/-3.90 years after transplant, with complete calcineurin-inhibitor (CNI) withdrawal. Three ...
Ridinger Heidrun - - 2009
Left ventricular hypertrophy (LVH) correlates with chronic renal failure and is one of the most important causes of cardiac mortality. The understanding of the molecular complexity of the disease will help to find biomarkers that open new perspectives about early diagnosis and therapy. This work describes the identification of mediators ...
da Costa William - - 2008
INTRODUCTION: Left ventricular hypertrophy (LVH) and obesity are important cardiovascular risk factors. This study evaluates the influence of obesity on the diagnostic performance of the most used electrocardiographic criteria for LVH in hypertensive patients. METHODS: One thousand two hundred four outpatients from the Hypertensive Unit of the Hospital São Paulo, ...
Ferri Claudio - - 2008
Left ventricular hypertrophy (LVH) detected by ECG has been shown to be associated with a higher prevalence of ventricular arrhythmias in members of the general population, in a case-control series of hypertensive patients and in never-treated hypertensive patients. In-keeping with this, it has been observed that hypertension-induced LVH increases the ...
Ngosuwan, Jantra
An eleven year old, spayed female French bulldog with pituitary-dependant hyperadrenocortism with a cardiac murmur and gallop rhythm presented with dyspnea, tachypnea, adventitious lung sounds, and weak pulses. Pleural effusion and a heart-based mass were demonstrated via radiography and echocardiography. The dog died while receiving supportive care. Necropsy and histopathology ...
Kunisek Juraj - - 2008
PURPOSE: To investigate the correlation between the prevalence of ventricular arrhythmias (VA) and the type and degree of left ventricular hypertrophy (LVH) in hypertensive patients using exercise testing and Holter monitoring. PATIENTS AND METHODS: A total of 192 patients (87 men and 105 women) without coronary disease were divided into ...
Palecek Tomas - - 2008
The aim of the study was to describe right ventricular (RV) structural and functional changes in Fabry disease (FD). A detailed echocardiographic examination was performed in 58 patients with proven FD (mean age 40 +/- 16 years, 24 men). RV hypertrophy (RVH) was present in 40% of affected subjects with ...
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