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Ghadri Jelena R - - 2014
As coronary computed tomography angiography (CCTA) has emerged as a non-invasive alternative for evaluation of coronary anatomy with a lower referral threshold than invasive coronary angiography (ICA), the prevalence of coronary anomalies in CCTA may more closely reflect the true prevalence in the general population. Morphological features of coronary anomalies ...
Shuaib Waqas W Department of Radiology and Imaging Sciences, Emory University Hospital, Atlanta, GA, USA, - - 2014
A broad spectrum of congenital coronary anomalies may be discovered on imaging and sometimes in the emergency setting on computed tomography (CT). Most coronary artery anomalies are of academic interest; however, a minority can cause morbidity and mortality and symptoms such as angina, myocardial infarction, or arrhythmias. These anomalies are ...
Karabay Kanber Ocal KO Department of Cardiology, Kadikoy Florence Nightingale Hospital, Kadikoy, Istanbul, - - 2013
Intercoronary continuity is a rare variance of coronary circulation. The importance of this rare anomaly is unknown. We present this rare anomaly in a patient with acute myocardial infarction.
Cannavale Giuseppe G Department of Radiological Sciences, Policlinico Umberto I, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, - - 2013
Malignant coronary artery anomalies and myocardial bridging are more common findings in young patients with cardiac symptoms, but these two associated yet different types of anomalies in an elderly patient has been rarely described. The following case describes the diagnostic use of 128-slice coronary-computed tomography images of an 82-year-old male, ...
Singh Neha N Department of Radiodiagnosis, King George Medical University (erstwhile CSMMU), Lucknow, Uttar Pradesh, India. - - 2013
Non-compaction of ventricular myocardium (NVM) is a rare clinical entity. It has been reported more frequently in recent years because of continuous improvements in imaging techniques and resolution. Although apical region of the left ventricle is the most commonly involved site, biventricular involvement has also been reported in the published ...
Sasikumar Navaneetha - - 2012
A 20 year-old male was diagnosed to have Ebstein's anomaly with severe right ventricular dysfunction. He was taken up for 1.5 ventricle repair. Post procedure, there was difficulty in weaning from cardiopulmonary bypass due to progressive right ventricular dilatation compromising the systemic output. An atrial septectomy did not help. Progressive ...
Lee Yonggu - - 2012
ABSTRACT: BACKGROUND: Type VI dual left anterior descending artery (LAD) is a rare coronary anomaly, the first case of which has recently been described. This is the first report of type VI dual LAD anomaly in which the patient presented with non-ST-segment elevation myocardial infarction and percutaneous coronary intervention was ...
Egidy Assenza Gabriele - - 2012
BackgroundEbstein anomaly is a rare and heterogeneous congenital heart defect affecting the tricuspid valve and right ventricular (RV) myocardium. Few studies have analysed the electrocardiographic features of Ebstein anomaly and none has addressed correlations with disease severity.MethodsPatients with Ebstein anomaly who had undergone electrocardiography and cardiac magnetic resonance (CMR) within ...
Uchinaka Ayako - - 2012
Myoblast sheet transplantation for cardiac failure is a promising therapy to enhance cardiac function via paracrine mechanism. However, their efficacies of treatment showed a gradual decline. The gene modification of the implanted myoblast is important in improving the long-term results of the treatment. Elastin fiber enhances the extensibility of the ...
Kraus M S - - 2012
Reasons for performing study: To date, no information is available on the true biological elimination half-life (T(1/2) ) of cardiac troponin I (cTnI) in the equine species. Such data are required to better evaluate the optimal time to acquire the cTnI sample following acute myocardial injury. Objective: To determine the ...
Kagaya Yutaka - - 2012
Erythropoietin (EPO) is a principal regulator that promotes proliferation and terminal differentiation of erythroid progenitor cells. EPO receptors are expressed not only in hematopoietic lineage cells but also in the cardiovascular system. We performed animal experiments using transgene-rescued EPO receptor null mutant mice (EpoR<sup>-/-</sup><inf>rescued</inf>) that express the EPO receptor exclusively ...
Pizarro Christian C Alfred I DuPont Hospital for Children, Wilmington, DE, - - 2012
Neonatal presentation of Ebstein's anomaly is associated with significant morbidity and mortality. We illustrate the technical aspects of the cone procedure and the closure of a ventricular septal defect, to achieve biventricular repair in a neonate. This includes the assessment of the leaftlet apparatus, detachment, division of chordae, annular plication, ...
Roberts Jason D - - 2011
Cardiac rupture represents a catastrophic complication of myocardial infarction with an exceedingly high mortality rate. In rare instances, a myocardial infarction can be complicated by 2 separate forms of rupture. The most common form of ventricular double rupture consists of free wall rupture in association with ventricular septal rupture. The ...
Narayan H K - - 2011
Hypoplastic left ventricle with congenital heart block has been reported previously in a fetus with concurrent left atrial isomerism and levo-transposition of the great arteries. We present the unusual case of an infant diagnosed in utero with hypoplastic left heart syndrome, a restrictive atrial septum and advanced heart block but ...
Oudit Gavin Y - - 2011
Angiotensin-converting enzyme 2 (ACE2) is a monocarboxypeptidase that metabolizes several peptides, including the degradation of angiotensin (Ang) II, a peptide with vasoconstrictive/proliferative effects, to generate Ang 1-7, which exerts vasodilatory/antiproliferative actions by acting through its receptor Mas. ACE2 is a multifunctional enzyme, and its actions on other vasoactive peptides, including ...
Alazzoni Ashraf - - 2011
Small randomized trials in patients with ST-elevation myocardial infarction have shown that aspiration thrombectomy improves angiographic outcomes and may improve clinical outcomes. However, there remains a lack of reports on device-related complications. We report a case of a device complication involving the left main coronary artery where a large burden ...
Desai Ravi V - - 2011
A 37-year-old woman was diagnosed to have a small ventricular septal defect (VSD) with high velocity tricuspid regurgitation (TR) that was attributed to atrio-VSD (Gerbode). Cardiac MR revealed a small subaortic VSD in the membranous portion of the interventricular septum. The atrioventricular portion was intact. Cardiac MR clearly showed flow ...
Arrenberg Aristides B - - 2010
The cardiac pacemaker controls the rhythmicity of heart contractions and can be substituted by a battery-operated device as a last resort. We created a genetically encoded, optically controlled pacemaker by expressing halorhodopsin and channelrhodopsin in zebrafish cardiomyocytes. Using patterned illumination in a selective plane illumination microscope, we located the pacemaker ...
Monfredi Oliver - - 2010
The sinoatrial node is the primary pacemaker of the heart. Nodal dysfunction with aging, heart failure, atrial fibrillation, and even endurance athletic training can lead to a wide variety of pathological clinical syndromes. Recent work utilizing molecular markers to map the extent of the node, along with the delineation of ...
Khaja Azamuddin - - 2011
The aims of this study are to evaluate the cardiac safety of the Stinger S-200 Conducted Energy Weapon Device (CED) (Stinger Systems, Tampa, Fla) on a human-sized pig model and to test the effect of various commercially available CEDs, specifically the Stinger S-200, TASER M26 (Taser International, Scottsdale, Ariz), and ...
Shinohara Tetsuji - - 2010
The mechanisms of sinoatrial node (SAN) dysfunction in heart failure (HF) remain unclear. We hypothesized that impaired rhythmic spontaneous sarcoplasmic reticulum Ca(2+) release (Ca(2+) clock) plays an important role in SAN dysfunction in HF. HF was induced in canine hearts by rapid ventricular pacing. The location of pacemaking sites was ...
Celebi Ozlem Ozcan - - 2010
Inappropriate sinus tachycardia (IST) is characterised by an exaggerated increase of heart rate in response to normal physiologic demands. Therapeutic options including medical and radiofrequency ablation interventions are still under debate. Ivabradine inhibits spontaneous pacemaker activity of the sinus node by selectively blocking If channels of pacemaker cells. Here we ...
John Camm A - - 2010
In the early 1950s, Dr Aubrey Leatham established a cardiac unit at St. George's Hospital, Hyde Park Corner, London. He developed and taught the essential clinical skill of cardiac auscultation. Under his guidance a clinical department for the care of cardiac patients was developed and coupled to physiological academic research. ...
Bakker Martijn L - - 2010
Disorders of the cardiac conduction system occur frequently and may cause life-threatening arrhythmias requiring medication or electronic pacemaker implantation. Repair or regeneration of conduction system components is currently not possible due to limited knowledge of the molecular regulation of pacemaker myocardium. Origin and development of the cardiac conduction system have ...
Issa Ziad F - - 2010
We report a case of inadvertent transarterial implantation of dual-chamber pacemaker leads; the ventricular lead positioned across the aortic valve into the left ventricle and the atrial lead curving in the aortic root with the tip positioned into the left circumflex artery, resulting in acute myocardial infarction. The diagnosis was ...
Höcker J - - 2010
BACKGROUND: The surgical stress index (SSI) is a new monitoring tool for the assessment of nociception during general anaesthesia. It is calculated based on the heart beat interval and the pulse wave amplitude. Correlation of SSI with nociceptive stimuli and opioid effect-site concentrations has been demonstrated, but the influence of ...
O'Neill Rory - - 2012
Background: Lead dislodgement has been shown to be the most common complication in the first 30 days after pacemaker insertion. Although it is rare, pneumopericardium with tamponade can also result. Objectives: We present a case of an extremely rare delay from cardiac pacemaker insertion to lead migration with resulting pneumopericardium ...
Ruhparwar Arjang - - 2010
When sinus node or atrioventricular (AV) node cells are damaged by disease, the implantation of an artificial cardiac pacemaker becomes necessary. In search for a biological alternative, the objective of this study was to demonstrate whether in vivo adenoviral gene transfer of Adenylate-Cyclase type VI (AC-VI) can create biological pacemaker ...
van de Sandt F M - - 2010
A 62-year-old patient presented with dizzy spells after her dual chamber pacemaker (Medtronic Enrhythm P1501DR), implanted for complete AV block, had been reprogrammed to deliver antitachycardia therapy (ATP) for paroxysmal atrial tachycardia. Her symptoms were caused by inhibition of ventricular backup pacing during ATP, leading to ventricular asystoles. Inhibition was ...
Taha Nima - - 2010
Doppler echocardiography of mitral inflow or aortic outflow or both has been validated and advocated to guide biventricular (Biv) pacemaker optimization. A comprehensive and tailored Doppler echocardiographic evaluation may be required in patients with heart failure to assist with Biv pacemaker optimization. The third heart sound (S(3)), an acoustic cardiographic ...
Madershahian Navid - - 2010
In the presented case, a screw-in pacemaker lead migrated through the right ventricle, pericardium, left hemidiaphragm, and the left liver lobe into the epigastric region. The rarity of the case is based upon the multiorgan perforation without development of relevant pericardial effusion or intra-abdominal bleeding. Lead extraction was performed uneventfully.
Bondke Hansjuergen - - 2010
AIMS: In the normal heart, myocardial contractility is augmented at elevated heart rates. This effect is known as force-frequency relationship (FFR). The FFR is altered in failing hearts and may be used to detect myocardial function impairment. Force-frequency relationship measurements usually require invasive techniques and have therefore rarely been used ...
Stone Jason Lyle - - 2010
The hazard of undetected cardiac pacemakers exploding in crematoria is well described. This short report describes the use of an affordable hand-held metal detector to detect cardiac pacemakers. Over the course of a year, the metal detector located 100% of cardiac pacemakers in a district general hospital mortuary. A simple ...
Christoffels Vincent M - - 2010
Pacemaker and conduction system myocytes play crucial roles in initiating and regulating the contraction of the cardiac chambers. Genetic defects, acquired diseases, and aging cause dysfunction of the pacemaker and conduction tissues, emphasizing the clinical necessity to understand the molecular and cellular mechanisms of their development and homeostasis. Although all ...
Matsutani Hideyuki - - 2010
We proposed a new acquisition method of coronary MDCT achieved by pacing rate resetting and/or propranolol or verapamil injection in patients with a pacemaker. Coronary MDCT was undertaken in 57 patients with a pacemaker (DDD: 51, VVI: 6) and in 2975 patients with sinus rhythm as control using Aquilion 64 ...
Chemello D - - 2010
The R-on-T phenomenon is a well-known entity that predisposes to dangerous arrhythmias. Typically, a premature ventricular complex occurring at the critical time during the T wave of the preceding beat precipitates ventricular tachycardia and fibrillation. This phenomenon can occur not only in asynchronous ventricular pacemakers, but also in synchronous pacemakers, ...
Molina J Ernesto - - 2010
Patients undergoing tricuspid valve replacement who already have a transvenous pacemaker system in the right ventricle are often recommended to have the ventricular lead removed and an epicardial system implanted. However, as a rule, the reliability of endocardial transvenous pacemaker leads has been superior to epicardial systems. Therefore, if the ...
Kumor Magdalena - - 2010
The aim of this study was to evaluate the reliability of pacemaker diagnostic function in diagnosing ventricular arrhythmias. We compared the occurrence of ventricular ectopic beats in 51 simultaneous 24-hour electrocardiogram (ECG) recordings and pacemaker event counters printouts. The diagnostic function of a pacemaker allowed also for a qualitative assessment ...
Mitov Vladimir - - 2010
INTRODUCTION: Persistent left superior vena cava represents a congenital vascular defect of the venous system, which often makes standard 58 cm endocardial lead placement impossible. CASE OUTLINE: A right chamber approach by the left cephalic vein was tried. This was impossible because standard endocardial lead (SJM Isoflex 5 1646T, bipolar ...
Bigdeli Amir K - - 2010
Complications of pacemaker implantation include myocardial perforation, venous thrombosis, vegetations of the tricuspid valve or pacing lead, and tricuspid regurgitation. We report a patient presenting with a case of delayed ventricular lead perforation through the right ventricle. The lead was uneventfully extracted under transesophageal echocardiographic observation in the operating room ...
Sánchez-Quintana Damián D Departamento de Anatomía y Biología Celular, Universidad de Extremadura, Facultad de Medicina, Badajoz, - - 2010
The development of ablation techniques for supraventricular arrhythmias in patients with Ebstein's anomaly have led to a need for better understanding of the morphology of the triangle of Koch and the position of the atrioventricular (AV) node in this structure. The study involved 17 human hearts: 11 with Ebstein's anomaly ...
Kohnen R F - - 2009
An 83-year-old female patient with symptomatic atrial fibrillation was referred to the Department of Cardiology for a scheduled electrocardioversion. Because of a junctional escape rhythm after the electrocardioversion she received a DDD pacemaker which was complicated by dyspnoea and ST-segment elevations in the inferior and precordial leads. Because of suspicion ...
Klimczak Artur - - 2010
Development and advances in heart pacing over the last nearly half a century allowed to save numerous lives by providing pacing support in bradycardia and complete heart block. Nevertheless, long-term follow up of patients with implanted pacemaker showed unfavorable remodeling of the heart, both from hemodynamic as well as electrical ...
Subramanian Anandaraja - - 2010
The introduction of new pacing algorithms for preserving intrinsic atrioventricular conduction has made the interpretation of normal pacemaker function at times challenging. Electrocardiographic (ECG) findings in a patient with apparent pacemaker malfunction is presented and interpretation given. During this process, the managed ventricular pacing algorithm is described to interpret the ...
Massoure P L - - 2009
A 31-year-old man had undergone pacemaker implantation for complete atrio-ventricular block six years before. Permanent ventricular stimulation was seen on the ECG. The QRS complex was negative in leads I, VL and V2 to V5. The ventricular lead tip was found to be screwed into a branch of the great ...
Vaccarino Guillermo Nuncio - - 2009
The presence of large lead vegetations poses additional difficulties for explantation because many methods cannot be used due to the potential hazard of embolism. We report two patients with large vegetation on the ventricular lead due to endocarditis and one of them with an atrial septal defect associated. It was ...
N'guetta Roland - - 2011
Acute hyperkalemia may induce well-known serious cardiac arrhythmia. However, ventricular aberration including concealed conduction may also occur. We report the case of a 35-year-old woman who had a previous history of late-operated ventricular septal defect communication and DDD pacemaker was admitted for dyspnea. During hospitalization, an acute hyperkalemia induced sinoatrial ...
DAS Mithilesh K - - 2009
In recent years, the role of implantable pacing devices has expanded beyond the arrhythmia horizon and contemporary pacemakers' attempt to meet the physiological needs of patients. Modern pacemakers' functions include various modes of dual-chamber pacing, rate-response algorithms with dual sensors for optimum physiological response, cardiac resynchronization therapy (CRT), arrhythmia-prevention algorithms, ...
Chan Yau-Chi - - 2009
Normal heart rhythms originate in the sinoatrial node. HCN-encoded funny current (I(f)) and the Kir2-encoded inward rectifier (I(K1)) counteract each other by respectively oscillating and stabilizing the negative resting membrane potential, and controlling action potential firing. Therefore, I(K1) suppression and I(f) overexpression have been independently exploited to convert cardiomyocytes (CMs) ...
Novak Miroslav - - 2009
AIMS: To evaluate intracardiac findings near leads and causes of death in pacemaker/defibrillator patients. METHODS AND RESULTS: Special autopsy was performed on 78 patients deceased in a hospital. Age at death was 77.9 +/- 10.0, implantation-death interval 4.0 +/- 3.3 years, ventricular leads n = 78, and atrial leads n ...
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