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Adabag Selcuk S Veterans Affairs Health Care System, Minnesota, MN, USA; University of Minnesota, Minnesota, MN, - - 2014
Sudden cardiac death (SCD) accounts for ∼ 25% of all deaths in heart failure with preserved ejection fraction (HFpEF). However, strategies to identify HFpEF patients at a higher risk of SCD have not been developed. We studied 4128 patients with HFpEF enrolled in the Irbesartan in Patients with Heart Failure and Preserved ...
Blatt Alex A Tel Aviv University, Israel. - - 2014
Background: Despite successful primary reperfusion therapy patients may develop large myocardial infarction related in part to reperfusion injury. Induction of mild therapeutic hypothermia (TH) applied in patients has demonstrated beneficial effect in reducing reperfusion injury.Aims: To evaluate the feasibility and safety of adjunctive mild TH to primary percuateneous coronary intervention ...
Pocock Stuart S London School of Hygiene and Tropical Medicine, UK - - 2014
A reliable prediction tool is needed to identify acute coronary syndrome (ACS) patients with high mortality risk after their initial hospitalization. EPICOR (long-tErm follow uP of antithrombotic management patterns In acute CORonary syndrome patients: NCT01171404) is a prospective cohort study of 10,568 consecutive hospital survivors after an ACS event (4943 ...
Chung H-T HT Division of Cardiology, Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, Taoyuan, - - 2014
Patients with systemic lupus erythematosus (SLE) have a higher risk of myocardial involvement, which can result in ventricular dysfunction. Little is known about the chronic influence of SLE on heart function in children and adolescents. This is the first study to demonstrate long-term changes in left ventricular function in patients ...
Delewi Ronak R Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Interuniversity Cardiology Institute of the Netherlands, Utrecht, The - - 2014
This study reports the long-term follow-up of the randomised controlled HEBE trial. The HEBE study is a multicentre trial that randomised 200 patients with large first acute myocardial infarction (AMI) treated with primary percutaneous coronary intervention to either intracoronary infusion of bone marrow mononuclear cells (BMMCs) (n=69), peripheral blood mononuclear ...
Banka Puja - - 2014
We sought to identify cardiovascular magnetic resonance (CMR) parameters associated with successful univentricular to biventricular conversion in patients with small left hearts. Patients with small left heart structures and a univentricular circulation who underwent CMR prior to biventricular conversion were retrospectively identified and divided into 2 anatomic groups: 1) borderline ...
Garcia-Dorado David D Cardiology Department, Vall d'Hebron Hospital, Universitat Autónoma de Barcelona, Barcelona, Spain. Electronic address: - - 2014
The effect of intracoronary adenosine (ADO) on ST-segment elevation myocardial infarction (STEMI) size and adverse remodeling is not well established. In a double-blind trial, 201 patients with STEMI were randomized to receive percutaneous coronary intervention (PCI) within 6hours of symptom onset, 4.5mg ADO or saline immediately prior to reperfusion. Primary ...
Sonmez Ertan E Bezmialem Vakıf University, Department of Emergency Medicine, İstanbul, Turkey. Electronic address: - - 2014
Chest pain and/or electrocardiogram changes in non-ST elevation or suspicious chest pain and cardiac marker elevations are defined as non-ST-elevation acute coronary syndrome (NSTE-ACS). Serial electrocardiogram and marker follow-up are needed to make a diagnosis of NSTE-ACS and to eliminate noncoronary chest pain (NCCP). Signal peptide-C1r/C1s, Uegf, and Bmp1-epidermal growth ...
Deguchi Ichiro I Department of Neurology, Saitama Medical University International Medical Center, Hidaka, Japan. Electronic address: - - 2014
We compared the clinical outcomes of persistent atrial fibrillation (PeAF) and paroxysmal atrial fibrillation (PAF) in patients with cardioembolic stroke caused by nonvalvular atrial fibrillation (NVAF) because the nature of the fibrillation can cause persistent cerebral infarction. We classified 619 of 964 patients hospitalized with cardioembolic stroke between April 2007 ...
Glaveckaite Sigita S Department of Cardiovascular Medicine, Vilnius University; Centre of Cardiology and Angiology, Vilnius University Hospitals Santariskiu Klinikos, Santariskiu str, 2, Vilnius, 08661, Lithuania. - - 2014
This study sought to evaluate the relation between long-term segmental and global functional outcome after revascularisation in patients with chronic ischaemic left ventricular dysfunction (LVD) and baseline markers of viability: late gadolinium enhancement (LGE) transmurality and contractile reserve (CR). Forty-two patients with chronic ischaemic LVD underwent low-dose dobutamine- (LDD) and ...
Kim Seung Min SM Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Neurology, Veterans Health Service Medical Center, Seoul, South - - 2014
Ischemic lesions dynamically evolve during the acute phase of stroke. Although the ischemic lesion volume has been considered as a predictor of clinical outcome, it is still controversial whether early changes in ischemic lesion have prognostic information in addition to clinical variables. We hypothesized that early infarct growth on diffusion-weighted ...
Villa Chet R CR Cincinnati Children's Hospital Medical Center Heart Institute, Cincinnati, OH, USA. Electronic address: - - 2014
Plectin mutations have been reported in epidermolysis bullosa simplex with muscular dystrophy. We report the first case of left ventricular non-compaction in an 18-year-old male with epidermolysis bullosa simplex with muscular dystrophy. The patient was diagnosed with epidermolysis bullosa simplex after blistering was noted at birth. Motor function difficulties were ...
Henke Peter K PK Department of Surgery, University of Michigan, Ann Arbor, MI. Electronic address: - - 2014
Postoperative myocardial infarction (poMI) is a serious and costly complication. Multiple risk factors for poMI are known, but the effect of anemia and cardioprotective medications have not been defined in real-world surgical practice. Patients undergoing inpatient elective surgery were assessed at 17 hospitals from 2008 to 2011 for the occurrence ...
Cremer Paul C PC Heart and Vascular Institute, Cleveland Clinic, Cleveland, - - 2014
-In patients with possible acute coronary syndromes, guidelines recommend routine provocative testing after negative cardiac biomarkers. We hypothesized that myocardial perfusion imaging (MPI) would be low yield with limited short-term value and that early revascularization would not affect mortality. -We identified consecutive patients referred from our emergency department (ED) between ...
Chava Sreedivya S Department of Cardiology, College of Medicine, University of Vermont, Vermont, - - 2014
Pharmacoinvasive therapy (PIT) is a potential treatment for ST-segment elevation myocardial infarction patients who are not able to achieve primary percutaneous intervention (PCI) within guideline-recommended time limits. The risk for bleeding complications with PIT has not been studied in the setting of routine use of two selected bleeding avoidance strategies ...
Inciardi R M RM UOC Cardiologia II con Emodinamica "P. Giaccone" Hospital University of Palermo, Palermo, Italy - - - 2014
Arrhythmogenic right ventrticular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy characterized by fibrofatty replacement and a high risk of ventricular arrhythmias (VA) and sudden cardiac death (SCD). The aim of the present investigation is to examine the pathological profile and the clinical correlations in a group of ARVD/C patients. We conducted ...
Milvidaite Irena I Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, - - 2014
The objective was to evaluate the prognostic value of exercise myocardial perfusion scintigraphy (MPS) in patients who underwent coronary artery bypass grafting (CABG). A retrospective, one-center study of 361 patients with multivessel coronary artery disease was carried out. All the patients underwent MPS after CABG due to worsened health status. ...
Sousa Pedro A PA Cardiology Department, Faro Hospital, Faro, Portugal. Electronic address: - - 2014
Differentiation of ischemic from non-ischemic etiology in heart failure (HF) patients has both therapeutic and prognostic implications. One possible approach to this differentiation is direct visualization of the coronary tree. Multidetector computed tomography (MDCT) has emerged as an alternative to invasive coronary angiography (ICA), but its performance and additional clinical ...
Edison Eijiro Sugiyama ES Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, - - 2014
Our aim was to assess whether electrocardiographic left ventricular hypertrophy (ECG-LVH) is associated with a higher risk of cardiovascular disease (CVD) events, independent of 24-hour blood pressure (BP) and circulating levels of norepinephrine and hemostatic factors. In 514 older hypertensive patients (mean age 72.3 years; 37% men), we assessed ambulatory ...
Sun Bao-Liang BL Key Lab of Cerebral Microcirculation in Universities of Shandong, Taishan Medical University, Taian, 271000, People's Republic of China, - - 2014
Clinical scores are recommended for predicting cardiovascular and cerebrovascular risk in patients with cerebral infarction to inform secondary prevention. Blood biomarkers may improve prediction beyond clinical scores, and we conducted this analysis for the purpose of interpreting the association between serum H-FABP levels and cerebral infarction. Potential relevant studies were ...
Badar Athar A AA BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK Golden Jubilee National Hospital, Glasgow, - - 2014
Angina pectoris is common in patients with heart failure and reduced ejection fraction (HF-REF) but its relationship with outcomes has not been well defined. This relationship was investigated further in a retrospective analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). Four thousand, eight hundred and seventy-eight patients ...
Kim Ji-Hwan JH Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Contrast-induced acute kidney injury (CI-AKI) is a serious complication that is difficult to predict in patients with chronic kidney disease (CKD) undergoing percutaneous coronary intervention (PCI). The aim of this study was to investigate predictors and clinical outcomes of CI-AKI in patients with CKD after PCI. A total of 297 ...
Kunadian Vijay V Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Cardiothoracic Centre, Freeman Hospital, Newcastle Upon Tyne Hospitals National Health Service Foundation Trust, Newcastle upon Tyne, United - - 2014
There are limited data on the impact of anemia on clinical outcomes in unstable angina and non-ST-segment elevation myocardial infarction treated with an early invasive strategy. We sought to determine the short- and long-term clinical events among patients with and without anemia enrolled in the Acute Catheterization and Urgent Intervention ...
Kook Hyun Yi HY The Heart Center of Chonnam National University Hospital, Gwangju, Republic of - - 2014
Although the incidence of acute myocardial infarction (AMI) in Korea has been rapidly changed because of westernization of diet, lifestyle, and aging of the population, the recent trend of the myocardial infarction have not been reported by classification. We investigated recent trends in the incidence and mortality associated with the ...
Laut Kristina Grønborg KG Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. Electronic address: - - 2014
System delay (delay from emergency medical service call to reperfusion with primary percutaneous coronary intervention [PPCI]) is acknowledged as a performance measure in ST-elevation myocardial infarction (STEMI), as shorter system delay is associated with lower mortality. It is unknown whether system delay also impacts ability to stay in the labor ...
Valenti Renato R Division of Cardiology, Careggi Hospital, Florence, - - 2014
Coronary chronic total occlusion (CTO) carries a poor outcome in patients with acute myocardial infarction (AMI) treated with primary percutaneous coronary intervention (PCI). We sought to investigate the prognostic impact of a staged successful CTO-PCI in patients with AMI treated with primary PCI. Outcome analysis included consecutive patients treated by ...
Murat Sani Namik SN Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey - - 2014
Patients with acute coronary syndromes (ACSs) undergoing percutaneous coronary intervention (PCI) are at high risk of contrast-induced acute kidney injury (CI-AKI), a complication associated with poor clinical outcomes. Serum albumin (SA) levels are associated with cardiovascular mortality. We assessed the association between SA levels and the risk of CI-AKI in ...
Bohensky Megan - - 2014
IntroductionTo compare statin initiation and treatment non-adherence following a first acute myocardial infarction (MI) in patients with Inflammatory Rheumatic Disease (IRD) and the general population.MethodsA retrospective cohort study using a population-based linked database. Cases of first MI from July 2001 to June 2009 were identified based on International Classification of ...
Hoffman Scott J SJ Division of Cardiovascular Disease, Mayo Clinic, Rochester, - - 2014
Objectives We sought to determine neuroimaging patterns, ischemic mechanisms, and functional outcomes of ischemic stroke related to percutaneous coronary intervention (PCI) over a 16-year period. Background Stroke is a feared complication of PCI, associated with poor patient outcomes. The majority of strokes that occur after PCI are ischemic rather than ...
Riksen Niels P NP aDepartment of Internal Medicine bPharmacology-Toxicology, Radboud university medical center, Nijmegen, the - - 2014
In overweight patients with diabetes, treatment with metformin improves cardiovascular outcomes. This observation has fuelled the hypothesis that metformin has direct cardiovascular protective properties over and above glucose lowering. Here, we discuss the various cardiovascular effects of metformin observed in preclinical studies and recent clinical trials in patients, which fail ...
Eitel Ingo I Department of Internal Medicine-Cardiology, University of Leipzig-Heart Center, Leipzig, Germany; Department of Cardiology, Angiology, Intensive Care Medicine, University of Lübeck, Medical Clinic II, Lübeck, Germany. Electronic address: - - 2014
Although the prognostic value of findings from cardiac magnetic resonance (CMR) imaging has been established in single-center center studies in patients with ST-segment elevation myocardial infarction (STEMI), a large multicenter investigation to evaluate the prognostic significance of myocardial damage and reperfusion injury is lacking. The aim of this study was ...
Strauss Bradley H BH Schulich Heart Center, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada. Electronic address: - - 2014
Up to 20% of all coronary angiograms reveal coronary chronic total occlusions (CTOs). The lack of robust type A evidence with hard clinical outcomes on the benefits of CTO revascularization has hampered attempts to develop recommendations regarding the optimal management of CTOs. This review presents issues surrounding CTO revascularization within ...
Bajraktari Gani G Public Health and Clinical Medicine, Umeå University, Umeå, Sweden; Clinic of Cardiology, University Clinical Center of Kosova, University of Prishtina, Republic of - - 2014
Heart failure (HF) represents a serious clinical and public cause of mortality, morbidity, as well as healthcare expenditures. Guidelines for treatment of HF join in recommending multimedical regimen at targeted doses as the best medical strategy, despite that a significant percentage of patients remain symptomatic. Studies have shown that these ...
Rubattu Speranza S aIRCCS Neuromed, Pozzilli bDept. of Clinical and Molecular Medicine, School of Medicine and Psychology, Sapienza University of Rome, Ospedale S. Andrea, Rome cDept. of Science of Public Health and Infectious Diseases, School of Pharmacy and Medicine, Sapienza University of Rome, Rome, - - 2014
The role of C2238/atrial natriuretic peptide (ANP) minor allele, at the T2238C ANP gene variant, as a predisposing risk factor for acute cardiovascular events, has been previously reported. We aimed at evaluating, by a retrospective approach, the long-term impact of C2238/ANP-minor allele carrier status toward the risk of recurrent acute ...
Gerber Yariv Y From the Department of Health Sciences Research,; Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, 69978, Israel. Electronic address: - - 2014
Contemporary data on the epidemiology of myocardial infarction in the population are limited and derived primarily from cohorts of hospitalized myocardial infarction patients. We assessed temporal trends in incident and recurrent myocardial infarction, with further partitioning of the rates into pre-hospital deaths and hospitalized events, in a geographically-defined community. All ...
Condén Emelie E Centre for Clinical Research, Uppsala University, Västmanland County Hospital, Västerås, - - 2014
This study examined the prevalence of Type D personality and the temporal stability, internal consistency, and construct validity of the DS14 at three time points after myocardial infarction. The prevalence was 14.0% during hospitalization, 25.1% at 1 month, and 19.2% at 12 months. A total of 6.1% of the patients were classified ...
El-Menyar Ayman A Department of Clinical Medicine, Weill Cornell Medical School, Doha, Qatar Clinical Research, Trauma Section, Hamad Medical Corporation (HMC), Doha, Qatar Internal Medicine, Cardiology Section, Ahmed Maher Teaching Hospital, Cairo, Egypt - - 2014
We analyzed the clinical presentation and outcomes (from 2003 to 2013) of heart failure (HF) with apparently normal systolic function (HFPEF). Based on the echocardiographic left ventricular ejection fraction (LVEF), patients were divided into 2 groups, group 1 (<50%) and group 2 (≥50%). Of 2212 patients with HF, 20% were ...
Lee Sunyoung S Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, - - 2014
To evaluate the frequency, CT findings, and fate of multiple infarcted regenerative nodules in patients with liver cirrhosis after variceal bleeding or septic shock. During a recent 3-year period, 492 patients with hematemesis or melena (n = 445) and septic shock (n = 47) in liver cirrhosis visited our hospital. After applying the exclusion ...
Ustun Nilgun N Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey, - - 2014
The aim of this study was to evaluate left ventricular systolic and diastolic function using speckle tracking echocardiography (STE) in order to detect subclinical left ventricular dysfunction in patients with ankylosing spondylitis (AS). Twenty-six AS patients (age 43.7 ± 11.8 years, disease duration 11.83 ± 10.98 years) and 26 healthy controls, matched for age, ...
Aissaoui Nadia - - 2014
IntroductionThere are little data about patients with cardiogenic shock (CS) who survive the early phase of acute myocardial infarction (AMI). The aim of this study was to assess long-term (5-year) mortality among early survivors of AMI, according to the presence of CS at the acute stage.MethodsWe analyzed 5-year follow-up data ...
Bradshaw Pamela J - - 2014
Disparities in the use of invasive coronary artery revascularisation procedures to manage acute myocardial infarction (AMI) have been found in several developed economies. Factors such as socio-economic status, income and funding source may influence the use of invasive procedures and have also been associated with ongoing care. The objectives of ...
Song T-J - - 2014
There has been little information regarding the impact of unrecognised brain infarctions (UBIs) on stroke outcome in patients with non-valvular atrial fibrillation (NVAF). By using volumetric analysis of ischaemic lesions, we evaluated the potential impact of UBIs on clinical outcome according to their presence and categorised type. This study enrolled ...
Sekercioglu Nigar N Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, - - 2014
Although multivessel coronary artery disease has been associated with poor health outcomes in patients with acute ST-segment elevation myocardial infarction (STEMI), the optimal approach to revascularization remains uncertain. The objective of this review was to determine the benefits and harms of culprit vessel only vs immediate complete percutaneous coronary intervention ...
Ulvenstam Anders A From the Östersund Hospital, Frösön, Sweden (A.U., A.M.); Skaraborg Hospital Skövde, Sweden (U.K.); Department of Medicine, Karolinska Institutet, Solna, Sweden (T.J.); Unit of Research, Education and Development, Östersund Hospital, Frösön, Sweden (L.S.); and Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden (A.U., A.M., U.K., T.M.). - - 2014
Ischemic stroke after acute myocardial infarction is an important complication. It is unknown whether the risk has changed because the treatment of acute myocardial infarction has improved during the past decade. There is also conflicting data about predictors of stroke risk. To obtain the 1-year incidence of stroke after acute ...
Zhang Baowei B Department of Cardiology, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu, - - 2014
Fragmented QRS complexes (fQRS) were associated with left ventricular mass (LVM) in hypertensive patients. Our study aimed to investigate the association between fQRS and left ventricular hypertrophy (LVH) in hypertensive patients. Two hundred thirty-six hypertensive patients were divided into fQRS group and non-fQRS group. fQRS were defined as the presence ...
Ji Mi Seon MS Chonnam National University Hospital, Gwangju, Republic of - - 2014
Despite good treatment, there are residual risks in acute myocardial infarction (AMI) patients, and low level of high-density lipoprotein-cholesterol (HDL) has drawn attention as a possible cause. However, the impact of low HDL on ST-segment-elevation myocardial infarction (STEMI) compared with non-ST-segment-elevation myocardial infarction (NSTEMI) is not clear. Our aim was ...
Mark Daniel B - - 2014
The STICH (Surgical Treatment for Ischemic Heart Failure) trial compared a strategy of routine coronary artery bypass grafting (CABG) with guideline-based medical therapy for patients with ischemic left ventricular dysfunction. To describe treatment-related quality-of-life (QOL) outcomes, a major prespecified secondary end point in the STICH trial. Randomized trial. (ClinicalTrials.gov: NCT00023595). ...
Kilickesmez Kadriye Orta KO aDepartment of Cardiology, Istanbul University Institute of Cardiology bDepartment of Biochemistry, Istanbul University Medical Faculty, Istanbul, - - 2014
Spontaneous reperfusion (SR) was associated with better clinical outcomes and lower incidence of major adverse cardiovascular events. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor peptide and elevated systemic ET-1 levels predict a poor prognosis in patients with ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the relationship between systemic ...
MacCallum Caroline C Melbourne Brain Centre at Royal Melbourne Hospital, Melbourne, - - 2014
Background: Early decompressive hemicraniectomy following malignant middle cerebral artery (MCA) infarction reduces mortality and improves clinical outcome. Imaging predictors of malignant infarction may serve as 'red flags', prompting intensive neurological monitoring and timely intervention. Our objective is to investigate whether lower ASPECTS (Alberta Stroke Program Early CT Score) is associated ...
Child Nicholas - - 2014
Myocardial crypts are discrete clefts or fissures in otherwise compacted myocardium of the left ventricle (LV). Recent reports suggest a higher prevalence of crypts in patients with hypertrophic cardiomyopathy (HCM) and also within small samples of genotype positive but phenotype negative relatives. The presence of a crypt has been suggested ...
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