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Kedev Sasko S University Clinic of Cardiology, Interventional Cardiology, Vodnjanska 17, Skopje, Macedonia 1000. - - 2014
To compare the short- and long-term outcomes of transradial approach (TRA) versus transfemoral approach (TFA) for primary percutaneous coronary intervention (PPCI) during a complete institutional transition from TFA to TRA. An all-comer population of ST-elevation myocardial infarction (STEMI) patients (n=1808) who underwent PPCI using TRA (n=1162) and TFA (n=646) from ...
Patel Niket N Cardiology Department, Oxford Heart Centre, Oxford University Hospitals, Oxford, United - - 2014
This study sought to evaluate in-hospital outcomes and 3-year mortality of patients presenting with unprotected left main stem occlusion (ULMSO) treated with primary percutaneous coronary intervention (PPCI). Limited data exists about management and outcome following presentation with ULMSO. From January 1, 2007 to December 21, 2012, 446,257 PCI cases were ...
O'Donoghue Michelle L ML TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, - - 2014
Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme. To evaluate the efficacy and safety of darapladib in patients after an acute coronary syndrome (ACS) event. SOLID-TIMI 52 was a multinational, double-blind, ...
Gili Sebastiano S Division of Cardiology, Department of Internal Medicine, Città della Salute e della Scienza, Turin, - - 2014
Different definitions of periprocedural myocardial infarction (MI) after percutaneous coronary intervention (PCI) have been provided, but their impact on prognosis remains to be determined. Procedural data from consecutive patients undergoing PCI from 2009 to 2011 were revised to adjudicate diagnosis of periprocedural MI according to CK-MB increase (>3 × URL and >5 × URL), ...
Arbel Yaron Y Department of Cardiology, Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: - - 2014
High RDW values are associated with adverse prognosis in many clinical conditions including short and medium term outcome of patients with ST Elevation Myocardial Infarction (STEMI). The aim of the present study was to evaluate the association between RDW and long term mortality in STEMI patients undergoing primary angioplasty (PPCI). ...
Muschitz Gabriela K GK Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University Vienna, Vienna, Austria. Electronic address: - - 2014
Gastrointestinal complications occur frequently in intensive care patients with severe burns. Intestinal infarction and its deleterious consequences result in high mortality despite rapid surgical intervention. Our objective was to evaluate the aetiology of gastrointestinal infarction in intensive care patients with severe burns. We retrospectively evaluated all of the severe-burn victims ...
Mamas Mamas A MA Manchester Heart Centre, Manchester Royal Infirmary, Manchester, UK Cardiovascular Research Group, Institute of Cardiovascular Sciences, University of Manchester, Manchester, - - 2014
Between 10 and 30% of patients undergoing percutaneous coronary intervention (PCI) have left ventricular (LV) dysfunction. We investigate the association between LV function on early and late mortality outcomes in a national 'real-world' cohort undergoing PCI in the elective and acute coronary syndrome setting through analysis of the British Cardiovascular ...
Grodin Justin L JL Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195. Electronic address: - - 2014
Over the years several methods have been developed to reliably quantify functional capacity in patients with heart failure. Few studies have investigated the prognostic value of these assessment tools beyond cardio-renal prognostic biomarkers in stable patients with chronic heart failure. We performed Duke Activity Status Index (DASI, a self assessment ...
Orban M M Martin Orban, MD, Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Campus Großhadern, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377 München, Germany, Tel.: +49 89 7095 2361, Fax: +49 89 7095 8830, E-mail: - - 2014
There is limited clinical data comparing different P2Y12-receptor inhibitors in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock. The aim of the ISAR-SHOCK registry was to compare the clinical outcome of patients treated with clopidogrel vs prasugrel in this setting. Patients (n=145) with AMI complicated by cardiogenic shock ...
Kitagawa K K Department of Neurology, Tokyo Women's Medical University, Tokyo, - - 2014
The association between vascular risk factors and dementia is of interest. Several studies have shown that cerebral small vessel disease (SVD) is associated with dementia. However, the association between cerebral large vessel disease (LVD) and dementia has not been thoroughly examined. The Osaka Follow-up Study for Carotid Atherosclerosis, Part 2, ...
Pöyhönen Pauli - - 2014
Suspected nonischemic cardiomyopathy (NICM) is a common clinical setting with highly variable prognosis. Early noninvasive risk-stratification is important for justification of invasive examinations, specific treatment and patient surveillance. We studied the additional prognostic value of late gadolinium enhancement (LGE) and segmental wall motion abnormality (SWMA) extent on cardiovascular magnetic resonance ...
Hoogslag Georgette E GE Department of Cardiology, Leiden University Medical Center, Leiden, The - - 2014
Right ventricular (RV) function after ST-segment elevation myocardial infarction (STEMI) has important prognostic implications. However, the changes in RV function over time after STEMI and the incidence of RV remodeling remain unknown. The present study evaluated changes in RV dimensions and function in contemporary patients with first STEMI and assessed ...
Szpakowicz Anna A Department of Cardiology, Medical University of Bialystok, M. Sklodowskiej-Curie 24a, 15-276, Bialystok, - - 2014
Paraoxonase 1 (PON1) is an enzyme responsible for the antioxidant properties of high density lipoprotein (HDL). The activity of PON1 is decreased in patients with coronary artery disease, myocardial infarction or chronic kidney disease. rs662 and rs854560 are single nucleotide polymorphisms (SNPs) associated with PON1 activity and 10-year cardiovascular mortality ...
Bates Eric R ER University of Michigan Medical Center, Ann Arbor, MI - - 2014
Placebo-controlled trials with fibrinolytic agents first demonstrated important reductions in morbidity and mortality when reperfusion therapy was administered to patients with ST-segment elevation myocardial infarction (STEMI).(1,2) Although primary percutaneous coronary intervention (PCI) is a better reperfusion strategy when compared with fibrinolytic therapy in randomized clinical trials,(3) geographic access and logistical ...
Nguyen Si Van SV Department of Internal Medicine II, University of Yamanashi - - 2014
Background:After acute coronary syndrome (ACS), there is a high risk of recurrent cardiovascular events. Triglyceride-rich lipoproteins influence residual cardiovascular risk in patients taking statin. This study examined the predictive value of remnant lipoprotein level for secondary cardiovascular events in patients treated with statins after ACS.Methods and Results:A total of 190 patients treated ...
Montserrat Sílvia S Cardiology Department, Thorax Institute, Hospital Clinic, IDIBAPS(1), University of Barcelona, - - 2014
Predictors of second radiofrequency catheter ablation (RFCA) success are not well known. Surgical ablation is accepted for failed first RFCA but second-RFCA has less complications. Evaluate left atrial (LA) size and function as potential predictors of second-RFCA for atrial fibrillation (AF). Thirty-three healthy volunteers (group I) and 83 patients with ...
Girolami Antonio A Department of Medicine, University of Padua Medical School, Padua, Italy - - 2014
To investigate the occurrence of myocardial infarction or other acute coronary syndromes in rare congenital bleeding disorders. All patients with factor I (FI), factor II (FII), factor V (FV), factor VII (FVII), factor X (FX), factor XI (FXI), or factor XIII (FXIII) deficiency or abnormality reported to have presented a ...
Kimura Yuichi Y Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, Kumamoto, 860-8556, - - 2014
Thrombospondin-2 (TSP-2) is highly expressed in hypertensive heart. Interstitial fibrosis is frequently observed in hypertensive heart, and it is a characteristic feature of heart failure with preserved ejection fraction (HFpEF). We tested here the hypothesis that high TSP-2 serum levels reflect disease severity and can predict poor prognosis of patients ...
Liu Nan - - 2014
The key aim of triage in chest pain patients is to identify those with high risk of adverse cardiac events as they require intensive monitoring and early intervention. In this study, we aim to discover the most relevant variables for risk prediction of major adverse cardiac events (MACE) using clinical ...
Vidart Josi J Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, - - 2014
Context: The acute phase of the non-thyroidal syndrome (NTIS) is characterized by low triiodothyronine (T3) and high reverse T3 (rT3) levels, affecting up to 75% of critically ill patients. Oxidative stress has been implicated as a causative factor of the disturbed peripheral thyroid hormone metabolism. Objective: To investigate whether N-acetylcysteine ...
Rangel Inês I Cardiology Department, Centro Hospitalar de S. João, Porto, Portugal; Faculty of Medicine of Porto University, Porto, Portugal. Electronic address: - - 2014
The prognostic value of myocardium deformation measurements in chronic heart failure (CHF) is still poorly addressed. The purpose of this study was to evaluate the correlation of left ventricular (LV) global longitudinal strain (GLS) with clinical and prognostic indicators in patients with CHF and systolic dysfunction. Ambulatory patients with CHF ...
Jaguszewski Milosz M Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland, - - 2014
With increasing life expectancy in the western world, the aging population will compose a significant portion of the demographic. Notably, cardiovascular disease is particularly prevalent in the elderly population. The aim of the present study is to investigate the outcomes of octogenarians referred for urgent coronary angiography in the setting ...
Esponda Omar L OL Department of Internal Medicine, Hospital Universitario Dr Ramón Ruiz Arnau, Universidad Central del Caribe, Bayamón, PR, - - 2014
Recent studies suggest that the soluble triggering receptor expressed on myeloid cells-like transcript 1 (sTLT-1) facilitate atherothrombosis. Therefore, we evaluated sTLT-1 as a functional measure of atherothrombosis in acute coronary syndrome (ACS). Levels of sTLT-1 were determined by enzyme-linked immunosorbent assay on plasma from patients with potential ACS and compared ...
García-Paredes Teresa T Coronary Care Unit, Hospital Carlos Haya, Málaga, - - 2014
Prognostic systems are complex. So it is necessary to find tools, which are easy to use and have good calibration and discrimination. The objective of this study is to evaluate the usefulness of Killip, Thrombolysis In Myocardial Infarction (TIMI), and age to develop a new prognostic scale for patients with ...
Graham Colin A CA Accident and Emergency Medicine Academic Unit, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR. Electronic address: - - 2014
Chest pain is a common complaint among emergency department (ED) patients. The Thrombolysis in Myocardial Infarction (TIMI) and front door TIMI (FDTIMI) scores are used to risk stratify chest pain patients in many Western countries; they have not been validated in patients with undifferentiated chest pain in Asia. Our objective ...
Perl Leor L aDepartment of Cardiology, Rabin Medical Center, Petah Tikva bSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Recent literature shows a greater risk for adverse clinical outcomes following acute coronary syndrome (ACS) events in women undergoing a percutaneous coronary intervention (PCI), especially in young and diabetic patients. We aimed to assess the impact of sex on clinical results following ACS. From our database of all-comer PCI patients, ...
Luijendijk Paul P Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The - - 2014
Adult post-coarctectomy patients (CoA) demonstrate increased cardiovascular morbidity and mortality. The carotid intima-media thickness (CIMT), a marker for atherosclerosis, is increased in CoA. The aim was to evaluate the predictive value of CIMT for cardiovascular events. Consecutive CoA patients were prospectively studied during 10.1±0.7years follow-up. At baseline and follow-up echocardiography, ...
Mayyas Fadia F Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan. Electronic address: - - 2014
Coronary artery disease (CAD) is responsible for significant morbidity and mortality. Inflammatory, pro-thrombotic and structural factors contribute to the etiology of CAD. This study sought to determine the relationship of plasma endothelin-1 (pET-1), a potent vasoconstrictor, mitogen and modulator of cardiac inflammation, to clinical characteristics and outcomes of CAD patients. ...
Lee Ying-Hsiang YH Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota; Cardiovascular Medicine, Mackay Memorial Hospital, Taipei, - - 2014
The objective of the present study was to investigate the relation of ventricular premature complex (VPC) burden, origin, and electrocardiographic characteristics with left ventricular function and survival. Of 1,589 study patients, 388 (25%), 610 (38%), and 591 (37%) had low (<1,000/24 hours), moderate (1,000 to 10,000/24 hours), and high (>10,000/24 hours) VPC burden, ...
Boothroyd Lucy J LJ Cardiology Evaluation Unit, Institut national d'excellence en santé et en services sociaux, Montreal, Quebec, Canada. Electronic address: - - 2014
In a systematic province-wide evaluation of care and outcomes of ST elevation myocardial infarction (STEMI), we sought to examine whether a previously documented association between ambulance use and outcome remains after control for clinical risk factors. All 82 acute care hospitals in Quebec (Canada) that treated at least 30 acute ...
Huang Bi B State Key Laboratory of Cardiovascular Disease, Emergency and Critical Care Center, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of - - 2014
Current risk scores of ST-segment elevation myocardial infarction (STEMI) need sophisticated algorithm and were limited for bedside use. Our study aimed to evaluate the usefulness of admission shock index (SI) for predicting the short-term outcomes in patients with STEMI. Included were 7,187 consecutive patients with STEMI. The admission SI was ...
Huang Shao-Sung SS Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Healthcare and Management Center, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, - - 2014
The Thrombolysis In Myocardial Infarction (TIMI) score and Global Registry of Acute Coronary Events (GRACE) score have been validated as predictors of major adverse cardiovascular events (MACE) in patients with acute myocardial infarction (AMI). This study was undertaken to determine whether the CHADS2 score had good accuracy for predicting clinical ...
Kristiansen Jeppe Maagaard JM Kardiologisk Afdeling, Aalborg Universitetshospital, Hobrovej 18-22, 9000 Aalborg, Denmark. - - 2014
The objective of this study was to evaluate the incidence of death, cardiovascular events and the use of later non-scheduled imaging for coronary artery disease (CAD) in patients suspected for CAD and discharged without a need for further examination or treatment from an outpatient clinic following coronary computed tomography angiography ...
Rousan Talla A TA Section of Cardiovascular Disease, Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, - - 2014
Patients with diabetes mellitus (DM) presenting with acute myocardial infarction (AMI) have worse outcomes versus those without DM. Comparative contemporary data in patients presenting with AMI with insulin-requiring diabetes mellitus (IRDM), noninsulin-requiring diabetes mellitus (NIRDM), and newly identified DM (hemoglobin A1C level >6.5%) versus patients without DM are limited. This ...
Kim Jae Hee JH Department of Internal Medicine, Kyungpook National University Hospital, Daegu, - - 2014
The pattern and prognostic impact of "early" acute kidney injury (AKI) after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction have not been well established. From November 2005 to November 2011, 971 post-myocardial infarction patients who underwent primary PCI were analyzed. Early AKI was defined using ...
Abbasi Siddique A SA Department of Medicine, Noninvasive Cardiovascular Imaging Section, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Department of Radiology, Noninvasive Cardiovascular Imaging Section, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, - - 2014
The aim of this study was to investigate the association between major adverse cardiovascular events (MACEs) and inducible ischemia on regadenoson cardiac magnetic resonance (CMR) myocardial perfusion imaging (MPI) performed at 3.0 T. Regadenoson stress CMR MPI is increasingly used to assess patients with suspected ischemia; however, its value in ...
Taniguchi Tomohiko T Department of Cardiovascular Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto, - - 2014
The influence of preinfarction angina pectoris (AP) on long-term clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI) remains controversial. In 5,429 patients with acute myocardial infarction (AMI) enrolled in the Coronary Revascularization Demonstrating Outcome Study in Kyoto AMI Registry, the present ...
Azzalini Lorenzo L Interventional Cardiology Division, Department of Medicine, Montreal Heart Institute, Université de Montréal, Montréal, Quebec, - - 2014
We aimed to describe the impact of the vascular access used when patients are treated with primary percutaneous coronary intervention (PPCI) and to assess whether this translates into differences in angiographic outcomes. Patients with ST-elevation myocardial infarction who underwent PPCI were divided into 3 groups: successful radial access (RA), successful ...
Ghadri Jelena R - - 2014
As coronary computed tomography angiography (CCTA) has emerged as a non-invasive alternative for evaluation of coronary anatomy with a lower referral threshold than invasive coronary angiography (ICA), the prevalence of coronary anomalies in CCTA may more closely reflect the true prevalence in the general population. Morphological features of coronary anomalies ...
Jones William Schuyler WS Duke Clinical Research Institute, Duke University Medical Center, Durham, NC. Electronic address: - - 2014
In the TRACER trial, vorapaxar, a protease-activated receptor-1 antagonist, plus standard care in non-ST-segment elevation acute coronary syndrome (NSTE ACS) patients did not significantly reduce the primary composite end point but reduced a key secondary end point and significantly increased bleeding. History of peripheral artery disease (PAD) was a risk-enrichment ...
Negrusz-Kawecka Marta M Department and Clinic of Cardiology, Wroclaw Medical University, - - 2014
Cystatin C is a novel marker used in the diagnosis of preclinical chronic kidney disease (CKD). The aim of the study was to assess the role of cystatin C in the diagnosis of coronary artery disease. The study involved 63 patients of a mean age of 62.7 ± 9.5 years. The population was divided into two ...
Davis Melinda B MB Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, - - 2014
Elevated cardiac troponin I (cTnI) occurs in acute coronary syndrome (ACS) as well as various scenarios not associated with ACS. Simple clinical criteria can reliably exclude ACS among hospitalized patients with elevated cTnI. Records for patients hospitalized from January to April 2011 with elevated cTnI (>0.29 ng/dL) and an available ...
Shaikh Muhammad Kashif - - 2014
To validate the global registry of acute coronary event (grace) risk score in a Pakistani population at Tabba Heart Institute Karachi in patients with non ST-Elevation Myocardial Infarction (NSTEMI) and Unstable Angina (UA). In this prospective Observational registry study, 530 adults hospitalized patients with a diagnosis of Non-ST-Elevation Myocardial Infarction ...
Vakili Hossein H Associate Professor, Department of Interventional Cardiology AND Cardiovascular Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
The primary objective of primary percutaneous coronary intervention (pPCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) is not only to restore the blood flow in the infarct-related artery, but also to save the patients' quality and duration of their life. Since left ventricular ejection fraction (LVEF) is a ...
Fokkema Marieke L ML Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the - - 2014
Erythropoiesis-stimulating agents (ESAs) have been investigated in small studies in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Erythropoiesis-stimulating agents did not show a clear effect on left ventricular function or clinical outcome, but some studies suggested an increased risk of thromboembolic events. A systematic literature ...
Song Pil Sang PS Division of Cardiology, Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of - - 2014
We sought to assess the effect of the aldosterone receptor blocker, spironolactone, on 1-year clinical outcomes in all-comers with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention. A total of 10,309 AMI patients were recruited between November 2005 and April 2008 from a nationwide AMI registry in Korea. Patients were ...
Ofstad Anne Pernille AP Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, Norway. Electronic address: - - 2014
Patients with type 2 diabetes (T2D) are prone to develop preclinical myocardial dysfunction, but no single strategy to prevent progression to heart failure has been established. We aimed to assess whether intensified global cardiovascular (CV) risk factor control would improve left ventricular (LV) systolic and diastolic function as compared with ...
Farman Muhammad Tariq - - 2014
To determine the safety and efficacy of selective thrombus aspiration during Primary Percutaneous Coronary Intervention (PCI). This observational prospective study was conducted in the catheterization laboratory of a tertiary care cardiovascular centre. A total of 150 consecutive patients who underwent primary PCI were enrolled. Aspiration was done only when thrombus ...
Shuaib Waqas W Department of Radiology and Imaging Sciences, Emory University Hospital, Atlanta, GA, USA, - - 2014
A broad spectrum of congenital coronary anomalies may be discovered on imaging and sometimes in the emergency setting on computed tomography (CT). Most coronary artery anomalies are of academic interest; however, a minority can cause morbidity and mortality and symptoms such as angina, myocardial infarction, or arrhythmias. These anomalies are ...
Mirmohammadi Seyyed Jalil SJ Associate Professor, Department of Occupational Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, - - 2014
The evaluation of the ability for return to work among patients after myocardial infarction (MI) is subject to controversy. Understanding various factors, which may affect return to work process, will help in promoting effective communication between physicians and patients. Return to work is dependent on such factors as patients' functional ...
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