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Ryo Keiko - - 2012
Background: Isometric handgrip stress test is a simple method for detecting coronary artery disease (CAD). However, the value of this method alone is limited by relatively low sensitivity. This study thus aimed to investigate the usefulness of two-dimensional speckle-tracking strain combined with handgrip for CAD patients. Method: We studied 35 ...
Kakouros N - - 2012
Extensive work has been done over recent years to improve the spatial and temporal resolution of electrocardiogram (ECG)-gated cardiac computed tomography (CT). Advances in both hardware and software analysis have enabled the development of non-invasive coronary angiography. However, these high-quality examinations lend themselves to multiple additional applications beyond coronary angiography. ...
To Andrew Cy - - 2012
One of the diagnostic challenges in cardiology is the assessment of patients with suspected cardiomyopathies. The traditional approach involves clinical history and examination, followed by echocardiography and invasive angiography. Advances in cardiac MRI enable cardiologists to comprehensively assess both ischemic and nonischemic cardiomyopathies, providing information regarding cardiac anatomy, myocardial and ...
Hua Wei - - 2012
Cardiac resynchronization therapy (CRT) with biventricular pacing improves cardiac function, functional capacity and quality of life in selected patients with heart failure. The current study aimed to evaluate the efficacy of the intracardiac electrogram (IEGM)-based optimization method, QuickOpt(TM), in Chinese patients treated with CRT. Aortic time velocity integrals (AVTI) achieved ...
Gao Haokao - - 2012
The α(v)β(3) integrin represents a potential target for noninvasive imaging of angiogenesis. The purpose of this study was to evaluate a novel one-step labeled integrin α(v)β(3)-targeting positron emission tomography (PET) probe, (18)F-AlF-NOTA-PRGD2, for angiogenesis imaging in a myocardial infarction/reperfusion (MI/R) animal model. Male Sprague-Dawley rats underwent 45-min transient left coronary ...
Antonicelli Roberto - - 2012
We compared the diagnostic accuracy of 3-lead tele-ECGs to both 12-lead tele-ECGs and a conventional 12-lead ECG device (the gold standard). The subjects were older people (n = 107) with a mean age of 66 years. The overall agreement between two cardiologists on interpreting the 3-lead tele-ECG recordings was 97% ...
Tarkia Miikka - - 2012
PURPOSE: We evaluated four potential gallium-68 ((68)Ga)-labeled tracers for positron emission tomography (PET) imaging of myocardial perfusion in comparison with oxygen-15-labeled water ([(15)O]water) in healthy pigs. Four hexadentate salicylaldimine ligands derived from bis(3-aminopropyl)ethylenediamine (BAPEN) that showed promise in previous rat experiments were selected for this study. METHODS: Following an evaluation ...
Tsaftaris Sotirios A - - 2012
To investigate whether a statistical analysis of myocardial blood-oxygen-level-dependent (mBOLD) signal intensities can lead to the identification and quantification of the ischemic area supplied by the culprit artery. Cardiac BOLD images were acquired in a canine model (n = 9) with controllable LCX stenosis at rest and during adenosine infusion ...
Burri Manjula V - - 2012
Advances in computer processing speed and memory along with the advent of the microbeam former that can sample an entire crystal of the ultrasound transducer made possible the performance of 3-dimensional echocardiography in real time (RT3DE). The miniaturization of a 3-dimensional transducer permitting its extension to transesophageal mode rapidly expanded ...
Amano Yasuo - - 2012
To assess technical feasibility of navigator-gated 3-dimensional (3D) fat-suppressed delayed-enhancement magnetic resonance imaging (DE-MRI) at 3.0 T for simultaneous visualization of myocardial scars and coronary arteries. Thirty patients with various myocardial diseases underwent navigator-gated 3D fat-suppressed DE-MRI using a 3.0-T scanner. The ability of this imaging technique to detect myocardial ...
Sjögren Jane - - 2012
T2-weighted cardiovascular magnetic resonance (CMR) has been shown to be a promising technique for determination of ischemic myocardium, referred to as myocardium at risk (MaR), after an acute coronary event. Quantification of MaR in T2-weighted CMR has been proposed to be performed by manual delineation or the threshold methods of ...
Tseng Yi-Li - - 2012
The third and fourth heart sound (S3 and S4) are two abnormal heart sound components which are proved to be indicators of heart failure during diastolic period. The combination of using diastolic heart sounds with the standard ECG as a measurement of ventricular dysfunction may improve the noninvasive diagnosis and ...
Poorhosseini Hamidreza - - 2012
In this retrospective study, we compared the in-hospital and long-term outcomes of the on-label and off-label uses of drug-eluting stents.From April 2003 through June 2007, 1,538 patients underwent percutaneous coronary intervention with a drug-eluting stent (sirolimus or paclitaxel) at Tehran Heart Center. Off-label implantation of the drug-eluting stent was as ...
Chablais Fabian - - 2012
The mammalian heart is incapable of significant regeneration following an acute injury such as myocardial infarction(1). By contrast, urodele amphibians and teleost fish retain a remarkable capacity for cardiac regeneration with little or no scarring throughout life(2,3). It is not known why only some non-mammalian vertebrates can recreate a complete ...
Salleh Sheik Hussain - - 2012
Auscultation of the heart is accompanied by both electrical activity and sound. Heart auscultation provides clues to diagnose many cardiac abnormalities. Unfortunately, detection of relevant symptoms and diagnosis based on heart sound through a stethoscope is difficult. The reason GPs find this difficult is that the heart sounds are of ...
Tharwat Mohamed - - 2012
Echocardiography and intra-cardiac dimensions have not previously been reported in adult camels despite its potential application for medical purpose. The aim of this study was to describe the results of a prospective study, aiming to report normal cardiac appearance and normal chamber dimensions in adult camels (Camelus dromedarius). On the ...
Hoage Tiffany - - 2012
Zebrafish embryos have been extensively used to study heart development and cardiac function, mainly due to the unique embryology and genetics of this model organism. Since most human heart disease occurs during adulthood, adult zebrafish models of heart disease are being created to dissect mechanisms of the disease and discover ...
Witschey Walter R T WR Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA. - - 2012
Late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) is frequently used to evaluate myocardial viability, estimate total infarct size and transmurality, but is not always straightforward is and contraindicated in patients with renal failure because of the risk of nephrogenic systemic fibrosis. T2- and T1-weighted CMR alone is however relatively ...
Perez de Isla Leopoldo - - 2011
BACKGROUND: 3D echocardiography provides a complete evaluation of the aortic valve and adjacent structures and it improves the assessment of this cardiac region. Three-dimensional color-Doppler echocardiography (3DCDE) evaluation might improve the measurements of the functional regurgitant orifice in patients with Chronic Aortic Regurgitation (CAR). OBJECTIVES: Our aim was to compare ...
Montgomery David E - - 2011
AIMS: To evaluate the diagnostic power of abnormal global longitudinal strain (GLS) to detect non-obstructive coronary artery disease (CAD) in the resting echocardiogram. GLS using two-dimensional speckle-tracking echocardiography (2D STE) is a powerful tool for detecting advanced CAD. However, the diagnostic power of 2D STE for detecting moderate, clinically unapparent ...
Séguéla Pierre-Emmanuel - - 2011
Background: Three-dimensional echocardiography (3DE) allows accurate estimation of left ventricular (LV) volumes and function in children. Because of the peculiar morphology of the right ventricle (RV), RV volumes and function assessment remain challenging. 3D software adapted for RV morphology is a promising noninvasive method. Aims: The aims of this study ...
Lee Hoshik - - 2011
Apnea of prematurity is an important and common clinical problem, and is often the rate-limiting process in NICU discharge. Accurate detection of episodes of clinically important neonatal apnea using existing chest impedance (CI) monitoring is a clinical imperative. The technique relies on changes in impedance as the lungs fill with ...
Gruszczynska Katarzyna - - 2011
To compare two semiautomated methods for measurement of infarcted myocardium area on delayed contrast enhanced magnetic resonance imaging, with histopathology findings as standard of reference. Percentage area of myocardial infarction was measured in 10 Yorkshire landrace pigs manually and using two semiautomated methods. The first (standard deviation method) used two ...
Kumar Andreas - - 2011
The aim of this study was to investigate the capabilities of balanced steady-state free precession (bSSFP) cardiac magnetic resonance imaging as a novel cine imaging approach for characterizing myocardial edema in animals and patients after reperfused myocardial infarction. Current cardiac magnetic resonance methods require 2 separate scans for assessment of ...
Arai Andrew E - - 2011
Cardiac magnetic resonance (CMR) is a noninvasive imaging method that can determine myocardial anatomy, function, perfusion, and viability in a relative short examination. In terms of viability assessment, CMR can determine viability in a non-contrast enhanced scan using dobutamine stress following protocols comparable to those developed for dobutamine echocardiography. CMR ...
Wecke Liliane - - 2011
BACKGROUND: In cardiac resynchronization therapy (CRT), left ventricular (LV) stimulation may lead to concomitant phrenic nerve stimulation (PNS). OBJECTIVE: To evaluate a new networked multi-electrode lead with 16 electrode segments (SEG) configured into groups of 4, forming a virtual band (VBAND) around the lead. Each electrode is individually programmable using ...
Kazemisaeid Ali - - 2011
Background: Assessment of left ventricular (LV) dyssynchrony has an important role in optimizing the selection of cardiac resynchronization therapy (CRT) candidates. We compared a new semiautomatic echocardiographic modality, tissue synchronization imaging (TSI) with a manual method, color-coded tissue Doppler imaging (TDI), in the assessment of LV dyssynchrony in patients with ...
Elefteriades John A - - 2011
Left ventricular assist device (LVAD) placement is a serious surgical procedure. At our center, we accumulated a very large experience with the Novacor LVAD from the very first clinical trial, as well as from more recent experiences with the Jarvik 2000 and the HeartMate II. This article discusses technical issues ...
Fathala Ahmed A Department of Cardiac Imaging and Nuclear Medicine, Medical Imaging Service, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. - - 2011
Myocardial perfusion single photon emission-computed tomography (MPS) has been one of the most important and common non-invasive diagnostic cardiac test. Gated MPS provides simultaneous assessment of myocardial perfusion and function with only one study. With appropriate attention to the MPS techniques, appropriate clinical utilization and effective reporting, gated MPS will ...
Vavere Andrea L AL The Johns Hopkins University, Baltimore, Maryland 21287, - - 2011
Multidetector coronary computed tomography angiography (CTA) is a promising modality for widespread clinical application because of its noninvasive nature and high diagnostic accuracy as found in previous studies using 64 to 320 simultaneous detector rows. It is, however, limited in its ability to detect myocardial ischemia. In this article, we ...
Mehra Vishal C - - 2011
Cardiovascular anatomic and functional testing have been longstanding and key components of cardiac risk assessment. As part of that strategy, CT-based imaging has made steady progress, with coronary computed tomography angiography (CTA) now established as the most sensitive noninvasive strategy for assessment of significant coronary artery disease. Myocardial CT perfusion ...
Gold Michael R - - 2011
Arrhythmia Detection with S-ICD Versus Transvenous ICDs. Background: The development of a totally subcutaneous implantable defibrillator (S-ICD) system requires a new approach for arrhythmia detection. To evaluate arrhythmia discrimination of one such system, the Subcutaneous versus Transvenous Arrhythmia Recognition Testing (START) study was designed as a prospective, multicenter trial comparing simulated ...
Busch Joshua L JL Division of Cardiology, University of Washington, Seattle, WA 98195, - - 2011
The objective of this study was to test the diagnostic accuracy of myocardial CT perfusion (CTP) imaging using color and gray-scale image analysis. Current myocardial CTP techniques have varying diagnostic accuracy and are prone to artifacts that impair detection. This study evaluated the diagnostic accuracy of color and/or gray-scale CTP ...
Hautvast Gilion L T F - - 2012
Quantitative analysis of short-axis functional cardiac magnetic resonance images can be performed using automatic contour detection methods. The resulting myocardial contours must be reviewed and possibly corrected, which can be time-consuming, particularly when performed across all cardiac phases. We quantified the impact of manual contour corrections on both analysis time ...
Brooks Steven C - - 2012
Even the best conventional manual cardiopulmonary resuscitation (CPR) is highly inefficient, producing only a fraction of normal cardiac output. Over the past several decades, many therapeutic devices have been designed to improve on conventional CPR during cardiac arrest and increase the probability of survival. This article reviews several adjuncts and ...
Chan William - - 2011
Cardiac magnetic resonance imaging (CMR) has matured into a robust, accurate and highly reproducible imaging modality for the assessment of cardiac function and ischemic heart disease (IHD). The unique physical properties of CMR permit depiction of pathology-specific tissue contrast based on differences in tissue composition such as myocardial oedema, necrosis ...
Jukema J Wouter - - 2011
The techniques and materials used during percutaneous coronary intervention have advanced considerably over the past 3 decades, yet restenosis remains one of the major drawbacks of this procedure. Many innovative technologies, including drug-eluting stents, with or without specific polymers, and fully biodegradable stents have been and continue to be developed ...
Nucifora G - - 2011
Transthoracic echocardiography is a practical, widely available non-invasive imaging technique examining cardiac structure and function at rest and during stress. However, diagnostically useful images are not provided in a non-negligible proportion of patients, mainly because of obesity and lung disease. The use of echo-contrast agents (microbubbles consisting of high molecular ...
Rahman Nasir - - 2011
Primary percutaneous intervention (PCI) in acute ST elevation myocardial infarction (MI) is a preferred way of treatment nowadays. Sometimes it becomes difficult to get good myocardial blood flow during PCI if clot burden is large. In this case of an elderly lady, the use of "Mother and Child Technique" combined ...
George Richard T - - 2011
Coronary MDCT angiography has been shown to be an accurate noninvasive tool for the diagnosis of obstructive coronary artery disease (CAD). Its sensitivity and negative predictive value for diagnosing percentage of stenosis are unsurpassed compared with those of other noninvasive testing methods. However, in its current form, it provides no ...
Wyffels Leonie - - 2011
A fluorescent zinc 2,2'-dipicolylamine coordination complex PSVue(®)794 (probe 1) is known to selectively bind to phosphatidylserine exposed on the surface of apoptotic and necrotic cells. In this study, we investigated the cell death targeting properties of probe 1 in myocardial ischemia-reperfusion injury. A rat heart model of ischemia-reperfusion was used. ...
Johnson Thomas V - - 2011
BACKGROUND: The aim of this study was to demonstrate improvement in the characterization of diastolic function in the routine practice of a clinical echocardiography laboratory after the implementation of a quality improvement initiative. The echocardiographic analysis of left ventricular (LV) diastolic dysfunction is an inherently complex process involving the integration ...
Porter Thomas R - - 2011
BACKGROUND: -Real time myocardial contrast echocardiography (RTMCE) permits the detection of myocardial perfusion abnormalities during stress echocardiography that may improve the accuracy of the test in detecting coronary artery stenoses (CAD). We hypothesized that this technique could be utilized following a bolus injection of the selective A2A receptor agonist regadenoson ...
Harpaz Nofar - - 2011
The Drosophila heart has become an exciting model for elucidating the molecular basis for cardiac function in higher organisms. To complement the genetic approaches that have recently identified an array of genes essential for cardiac function, we developed a method to obtain optimal semi-thin cross sections of embryonic, larval, and ...
Verrier Richard L RL Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, - - 2011
This consensus guideline was prepared on behalf of the International Society for Holter and Noninvasive Electrocardiology and is cosponsored by the Japanese Circulation Society, the Computers in Cardiology Working Group on e-Cardiology of the European Society of Cardiology, and the European Cardiac Arrhythmia Society. It discusses the electrocardiographic phenomenon of ...
Radzievsky Naira - - 2011
Eur J Clin Invest 2011 ABSTRACT: Background  We examined the feasibility of estimating left ventricular ejection fraction (LVEF) by a novel acoustic-based device [vibration response imaging (VRI); Deep Breeze]. Methods  One hundred and forty-one subjects (117 patients and 24 healthy volunteers; age 55 ± 15 years, 82% men) were examined by both VRI ...
Dhar Ritesh - - 2011
Cardiac positron emission tomography (PET) imaging has been used for more than 3 decades to study myocardial perfusion and metabolism, but for a majority of those years, confined to large academic and research centers with access to a cyclotron. With the advent of the generator-produced PET radionuclide Rubidium-82, PET myocardial ...
Temte Jon - - 2011
Presents a poem about fishing, which relates to hypothermic diuresis, hypotension and how it is resolved by NS bolus, mild demand ischemia. (PsycINFO Database Record (c) 2011 APA, all rights reserved).
Arai Andrew E - - 2011
Almost all published preclinical studies of cardioprotective agents include a measurement of area at risk, infarct size, and thus allow determination of myocardial salvage as an indicator of therapeutic benefit. Until recently, single-photon emission tomography (SPECT) imaging with injection of sestamibi prior to intervention was the only clinical method suitable ...
Gharib Ahmed M - - 2011
Four different techniques for 3-T whole-heart coronary magnetic resonance angiography (MRA) using free-breathing three-dimensional segmented parallel imaging and adiabatic T2-preparation were assessed. Coronary MRA at 3 T is improved by shortening the acquisition window more than employing the highest spatial resolution. Double-oblique whole-heart acquisitions result in better overall image quality ...
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