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Spargias Konstantinos - - 2008
INTRODUCTION: Percutaneous aortic valve replacement represents an alternative to conventional open-heart surgery for selected high-risk patients without the need for sternotomy, aortotomy, or cardiopulmonary bypass. We present the first Greek series of transcatheter prosthetic aortic valve implantation procedures, performed in our centre. METHODS: All 12 patients (age 81 +/- 5 ...
Yamamoto Kiyohito - - 2008
A 61-year-old man was admitted because of infective endocarditis. Echocardiography revealed the bicuspid aortic valve and a tricuspid pouch bulging into the right ventricle. Color Doppler demonstrated mild aortic regurgitation and left-to-right ventricular shunt through the lower part of the pouch. We successfully performed an aortic valve replacement and closed ...
Garcia Damien D Dept. of Radiology, University of Montreal Hospital, Montreal, Quebec H2L 2W5, Canada. - - 2009
Coronary flow reserve (CFR) is markedly reduced in patients with severe aortic valve stenosis (AS), but the exact mechanisms underlying this impairment of CFR in AS remain unclear. Reduced CFR is the key mechanism leading to myocardial ischemia symptoms and adverse outcomes in AS patients. The objective of this study ...
Mudd James O - - 2008
BACKGROUND: Left ventricular assist devices (LVADs) are an important therapy for selected individuals with advanced heart failure unable to wait for a suitable donor for transplantation. Pulsatile LVADs are associated with commissural fusion of the aortic valve, yet little is known about this association with newer generation continuous axial flow ...
Russo Claudio F - - 2008
OBJECTIVE: Patients with bicuspid aortic valve are at increased risk for aortic complications. METHODS: A total of 115 consecutive patients with bicuspid aortic valve disease underwent surgery of the ascending aorta. We classified the cusp configuration by 3 types: fusion of left coronary and right coronary cusps (type A), fusion ...
Sutherland Alexander - - 2008
Recent studies have proposed the use of D-dimer as a screening tool to "rule out" acute aortic dissection, claiming a sensitivity approaching 100%. We reviewed the literature to determine whether D-dimer can be used as the sole screening tool for acute aortic dissection. An Ovid MEDLINE search, 1966 to present, ...
Matulevicius Susan - - 2008
BACKGROUND: Caspase-3, an apoptosis protease, is expressed in atherosclerotic plaques. We examined the relationship between plasma caspase-3 levels, aortic compliance, and atherosclerosis. METHODS: Caspase-3 was measured in 3,221 subjects from the Dallas Heart Study. Electron beam computed tomography measures of coronary calcium (CAC) (n = 2,404) and magnetic resonance imaging ...
Tzemos Nikolaos N Peter Munk Cardiac Centre and Toronto Congenital Cardiac Centre for Adults, University Health Network, University of Toronto, Toronto, Ontario, - - 2008
Bicuspid aortic valve is the most common congenital cardiac anomaly in the adult population. Cardiac outcomes in a contemporary population of adults with bicuspid aortic valve have not been systematically determined. To determine the frequency and predictors of cardiac outcomes in a large consecutive series of adults with bicuspid aortic ...
Radbill Andrew E - - 2008
BACKGROUND: The clinical spectrum and underlying pathophysiology of isolated congenital complete heart block (CCHB) remain incompletely understood. Aortic dilation has been anecdotally observed in some children with CCHB, but detailed reports are lacking. OBJECTIVE: This study sought to systematically describe aortic size in children with CCHB and to investigate predictor ...
Swinkels Ben M - - 2010
Myocardial perforation by a guidewire after retrograde crossing of a stenotic aortic valve during cardiac catheterization is rare. We present a patient with calcific aortic stenosis who suffered this potentially life-threatening complication and in whom conservative treatment was successful. Early recognition of this complication is important for the operator performing ...
Gammie James S - - 2008
BACKGROUND: Aortic valve bypass (AVB; apicoaortic conduit) surgery relieves aortic stenosis (AS) by shunting blood from the apex of the left ventricle to the descending thoracic aorta through a valved conduit. We have performed AVB surgery as an alternative to conventional aortic valve replacement for high-risk AS patients. METHODS AND ...
Raghupathy Arun - - 2008
Although several studies have provided robust evidence about global differences for several cardiovascular emergencies, such as myocardial infarction and stroke, data were limited for aortic disease. The aim was to explore geographic variation in type A acute aortic dissection (TA-AAD) in a large group of consecutive patients. Patients (n = ...
Rega Filip R - - 2008
BACKGROUND: To evaluate mechanical and hematological compatibility of a pediatric, temporary left heart support system in a lamb model as a less traumatic alternative to the widely used ECMO. METHODS: A small, pulsatile rotary blood pump (target flow 0.5l/m at 80 mm Hg pressure head at 120 pulses per min) ...
Rodés-Cabau Josep - - 2008
The purpose of this study was to evaluate the feasibility and initial results of a multidisciplinary percutaneous aortic valve implantation (PAVI) program including the transfemoral approach (TFA) and the transapical approach (TAA). This was a prospective registry including all patients with symptomatic severe aortic stenosis who were evaluated for PAVI ...
Hage Fadi G - - 2008
We present a case of 61-year-old man that was evaluated for possible aortic stenosis but did not show a left ventricular outflow gradient on invasive assessment in the catheterization laboratory. Transthoracic echocardiography showed subaortic stenosis secondary to a discrete membranous structure in the left ventricular outflow tract. This is the ...
Rossebø Anne B - - 2008
BACKGROUND: Hyperlipidemia has been suggested as a risk factor for stenosis of the aortic valve, but lipid-lowering studies have had conflicting results. METHODS: We conducted a randomized, double-blind trial involving 1873 patients with mild-to-moderate, asymptomatic aortic stenosis. The patients received either 40 mg of simvastatin plus 10 mg of ezetimibe ...
Kaljusto Mari-Liis - - 2008
The case is reported of a 32-year-old male who sustained an aortic valve injury after a high-speed traffic accident. Several non-cardiac concomitant injuries were present, none of which was life-threatening. Cardiac surgery was performed on day 2 due to a grade III aortic valve insufficiency. As a large tear of ...
Misfeld M - - 2008
BACKGROUND: The risk of paraplegia and hospital death is the major concern in the surgical repair of descending and thoracoabdominal aortic pathologies. For specific indications, the evolving technology of endovascular stent grafting is becoming increasingly popular. We reviewed our results for elective surgical repair of various aortic pathologies with respect ...
Brizzio Mariano E - - 2008
The case is presented of chronic aortic valve endocarditis in a previously asymptomatic 54-year-old male. The main initial clinical manifestation was cardiogenic shock, but further examination revealed the presence of a large mobile mass attached to a bicuspid aortic valve, partially occluding the left coronary ostium. The patient underwent emergency ...
Pedersen Terje R - - 2008
It has been suggested by several retrospective studies that lipid-lowering therapy (compared with treatment with medications other than statins) retards the progression of aortic stenosis. Additional evidence for this has emerged from the prospective (nonrandomized) Rosuvastatin Affecting Aortic Valve Endothelium (RAAVE) study, although not from findings of the randomized, double-blind ...
Patel Angira - - 2008
A 10-day-old infant presented with tachypnea, harsh murmur, and cardiomegaly. Echocardiography revealed a multicystic mass invading the entire interventricular septum and protruding into the left ventricular cavity without left ventricular tract outflow tract obstruction and aortic stenosis. The mass was subsequently resected and biopsy revealed it to be a cardiac ...
de Jaegere Peter P T - - 2008
BACKGROUND: A 74 year old male with a history of postero-lateral myocardial infarction in 1993 and coronary bypass surgery in 1994 was referred to the outpatient clinic in a frail general condition with signs of dyspnoea at rest. INVESTIGATIONS: Physical examination, electrocardiography, laboratory tests, coronary angiography, abdominal angiography, Echo-doppler, transesophageal ...
Piazza Nicolo - - 2008
AIMS: To describe the procedural performance and 30-day outcomes following implantation using the 18 Fr CoreValve Revalving System (CRS) as part of the multicentre, expanded evaluation registry, 1-year after obtaining CE mark approval. METHODS AND RESULTS: Patients with symptomatic severe aortic stenosis and logistic Euroscore > or =15%, or age ...
Brown Morgan L - - 2008
OBJECTIVE: The European System for Cardiac Operative Risk Evaluation has been used to define a particularly high-risk group of patients for aortic valve replacement in whom alternative procedures, such as stent-mounted percutaneous valve procedures, may be appropriate. Our objective was to assess the validity of this risk assessment at a ...
Roedler Suzanne - - 2008
BACKGROUND: The purpose of this study was to evaluate outcome in patients with a small aortic root receiving either a standard CarboMedics mechanical aortic valve or a Top Hat CarboMedics valve (CarboMedics, Austin, TX), specifically designed for the small aortic root. METHODS: Between 1986 and 2006, 316 consecutive patients underwent ...
Rahimtoola Shahbudin H - - 2008
Early in 2006, the European Society of Cardiology (ESC) assigned the 2006 Denolin lecturer to provide a broad perspective on the asymptomatic patient with severe calcific valvular aortic stenosis (AS) in the older patient. Subsequently, in late 2006, American College of Cardiology/American Heart Association Guidelines and in 2007 ESC Guidelines ...
Galanti G - - 2010
OBJECTIVE: In this study, the impact of regular training on left ventricle morphology in a group of athletes with bicuspid aortic valve (BAV) was evaluated. DESIGN: Longitudinal cohort study. A group of competitive athletes with BAV was followed up with a yearly standard echocardiographic examination for 5 years. SETTING: Sport ...
Glatz Jenifer A - - 2008
BACKGROUND: Aortic atresia has been implicated as a risk factor for decreased survival after stage 1 palliation. Prior studies evaluating the association of anatomic subtypes and mortality report conflicting results. Our objective was to determine if mitral valve patency with aortic atresia is associated with increased mortality in hypoplastic left ...
Lo Sherwin S W - - 2008
Urgent requests for contrast computed tomographic scans of the thorax are often performed for suspected aortic dissections and pulmonary embolisms, both of which have clinical features similar to those seen in acute myocardial infarction. We present two cases with computed tomographic scans showing decreased myocardial enhancement, suggestive of acute myocardial ...
Casali Giovanni - - 2008
The aim of this study was to evaluate midterm echocardiographic results and changes in quality of life after aortic valve replacement with 17-mm St. Jude Medical Regent mechanical prostheses in patients with aortic valve stenosis. The study population was 34 women and 2 men, aged 31-83 years. Echocardiographic follow-up was ...
Michelena Hector I HI Divisions of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, - - 2008
Bicuspid aortic valve is frequent and is reported to cause numerous complications, but the clinical outcome of patients diagnosed with normal or mildly dysfunctional valve is undefined. In 212 asymptomatic community residents from Olmsted County, Minn (age, 32+/-20 years; 65% male), bicuspid aortic valve was diagnosed between 1980 and 1999 ...
Mihaljevic Tomislav - - 2008
OBJECTIVE: Recommendations for aortic valve replacement in severe aortic stenosis are based primarily on the presence of symptoms. However, the onset of symptoms is often insidious, potentially leading to delayed intervention and suboptimal results. Identifying factors that reduce the survival of patients undergoing aortic valve replacement could lead to revised ...
Luciani Giovanni Battista - - 2008
OBJECTIVES: Late results after stentless aortic valve replacement (AVR) may be jeopardized by progressive aortic dilatation. To define functional outcome using the intact non-coronary sinus technique, all patients operated using the stentless Edwards Prima Plus xenograft were assessed. METHODS: Between January 2000 and August 2007, 154 patients, aged 71 +/- ...
Nemes Attila - - 2008
In recent studies it has been demonstrated that a reduced coronary flow reserve (CFR) is independently associated with a less benign long-term outcome. Aortic stiffness is one of the most important cardiovascular risk factors predicting cardiovascular morbidity and mortality. Vasodilator stress transesophageal echocardiography (TEE) is a suitable method to evaluate ...
Khoynezhad Ali - - 2008
OBJECTIVE: The risk factors associated with death after thoracic endovascular aortic repair are poorly understood. The aim of this study is to analyze the risk factors associated with early and late mortality after thoracic endovascular aortic repair. METHODS: A total of 153 patients underwent 184 thoracic endovascular aortic repairs between ...
Levy Franck - - 2008
OBJECTIVES: We evaluated a large multicenter series of patients operated on for low-flow/low-gradient aortic stenosis (LF/LGAS) to stratify the operative risk, assess whether perioperative mortality has decreased over recent years, and analyze the post-operative outcome. BACKGROUND: Although LF/LGAS is classically associated with a high operative risk, few data are available ...
Svensson L G - - 2008
There are few cardiovascular disease entities that have as an impressive contribution to improved quality and duration of life as aortic valve disease correction. Although aortic valve stenosis is fairly common, particularly in elderly patients, between one third and two thirds go untreated, despite operative survival rates with the minimal ...
Knirsch Walter - - 2008
BACKGROUND: Isolated aortic valve stenosis in childhood is treated by balloon valvuloplasty. The role of independent risk factors for the outcome remains unclear. MATERIAL AND METHODS: We analysed the early and medium term outcome of balloon valvuloplasty in isolated aortic valve stenosis in 44 pediatric patients with isolated, severe aortic ...
Joudinaud Thomas M - - 2008
OBJECTIVE: Aortic homografts offer many advantages over prosthetic valves. However, homograft dysfunction due to degeneration or infection may lead to reoperation. Aortic valve replacement in patients who have undergone previous aortic root replacement with an aortic homograft remains a technical challenge. To assess reoperation events a retrospective review was conducted. ...
Estrera Anthony L - - 2008
BACKGROUND: Recent studies have described the importance of renal glomerular filtration rate (GFR) as a determinant of perioperative mortality in patients with aneurysms that involve the thoracoabdominal and abdominal aorta. We studied the impact of GFR on mortality following repair of ascending and arch aneurysms. METHODS: Between February 1991 and ...
Tao Liang - - 2008
BACKGROUND: Aortic insufficiency is a common disease in cardiac surgery. The frequency of native aortic valve repair in the young is increasing, reflecting a lack of consensus on the optimal therapeutic solution from the growing number of mechanical and biological prostheses. METHODS: Bovine pericardium was used to replace the coronary ...
Leggat Christopher S - - 2008
A case in which the bispectral index monitor underwent an acute change that was most likely the earliest indicator of an intraoperative stroke during replacement of an aortic valve is discussed in this study. The timely response to this intraoperative event may have facilitated a better outcome by virtue of ...
Farhat Fadi - - 2008
A 50-year-old man with an end-stage cardiac failure was referred to our institution for pre-transplantation assessment. An infrarenal aortic aneurysm (diameter 45 mm) was discovered and progressed (up to 59 mm) over a two-month period. Decision to perform aneurysmectomy with the support of an Impella Recover LP50 microaxial blood pump ...
Reszka Edyta - - 2008
INTRODUCTION: Several studies have been suggested that infectious agents may induce or progress the process of atherosclerosis in humans. In the present study, the samples of visually healthy human aortic wall were examined for the presence of Chlamydia pneumoniae, Mycoplasma pneumoniae, Helicobacter pylori, herpes simplex virus (HSV), and cytomegalovirus (CMV). ...
Moyssakis I - - 2008
BACKGROUND: Systemic sarcoidosis (Sar) is a granulomatous disorder involving multiple organs. Widespread vascular involvement and microangiopathy are common in patients with Sar. In addition, subclinical cardiac involvement is increasingly recognized in patients with Sar. However, data on the effect of Sar on the elastic properties of the arteries and myocardial ...
Arnold Raoul - - 2008
BACKGROUND: We asked whether aortic valve replacement using a mechanical prosthesis would allow normalization of left ventricular function and structure in children and young adults. METHODS: We performed a clinical follow-up examination in 30 patients with aortic valve replacement at 25 years of age or younger, including conventional and tissue ...
Bauer F - - 2008
BACKGROUND: In a pressure overloaded left ventricle, regional systolic function has often deteriorated despite normal ejection fraction. OBJECTIVE: To correlate regional systolic function obtained by tissue Doppler imaging (TDI) with improvement in functional status after aortic valve replacement in patients with aortic stenosis (AS). METHODS AND RESULTS: 24 hours before ...
Tao Liang - - 2008
Bovine pericardium was used to replace the right coronary leaflet to manage aortic insufficiency resulting from ventricular septal defect in 6 patients aged 15 to 34 years. Aortic insufficiency was severe in 5 patients and moderate in one. In all patients, the ventricular septal defect was repaired before aortic valvuloplasty. ...
Mohamed Salah A - - 2008
Acute aortic dissection (AAD) is a common fatal disease that affects the aorta and requires an urgent clinical intervention. A clinical feature of AAD is the characteristic tearing retrosternal pain often confused with that of myocardial infarction. In type A after Stanford, the biluminal progression is in the ascending aorta, ...
Alli Oluseun - - 2008
The acute aortic syndromes carry significant morbidity and mortality, especially when detected late. Symptoms may mimic myocardial ischemia, and physical findings may be absent or, if present, can be suggestive of a diverse range of other conditions. Maintaining a high clinical index of suspicion is crucial in establishing the diagnosis. ...
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