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Jantzen David W DW University of Michigan Congenital Heart Center,C.S. Mott Children's Hospital,Ann Arbor,Michigan,United States of - - 2014
Background: The term "borderline left ventricle" describes a small left heart that may be inadequate to provide systemic cardiac output and implies the potential need for a single-ventricle palliation. The aim of this study was to identify foetal echocardiographic features that help discriminate which infants will undergo single-ventricle palliation versus ...
De Vleeschauwer S S Department of Cardiovascular Sciences and Animal Facility, KU Leuven, Leuven, Belgium - - 2014
The ovine model is generally considered to be the best for testing bioprosthetic heart valve durability. Although echocardiography is the method of choice for the interim evaluation of the valve, literature on sheep echocardiography is scarce. Within the context of a study on treatment of pericardial heart valve prostheses, 19 ...
Doshi Jay V JV 1Department of Cardiology, Albert Einstein College of Medicine, Montefiore Medical Center, New York, NY 2Department of Medicine, Division of Cardiology, New York Medical College, Westchester Medical Center, Valhalla, New York 3Department of Family Medicine, Nassau University Medical Center, East Meadow, - - 2014
Mitral regurgitation (MR) is the most common cardiac valvular disease in the United States. Approximately 4 million people have severe MR and roughly 250,000 new diagnoses of MR are made each year. Mitral valve surgery is the only treatment that prevents progression of heart failure and provides sustained symptomatic relief. ...
Benjamin Mina M MM Department of Internal Medicine, Baylor University Medical Center, The Heart Hospital Baylor Plano and Baylor Heart and Vascular Hospital, Dallas, TX, - - 2014
Functional mitral regurgitation (FMR) occurs when normal or nearly normal mitral leaflets are prevented from proper coaptation by underlying left ventricular (LV) dysfunction, mitral annular dilation, or both. FMR is associated with an adverse prognosis in nonischemic or ischemic LV dysfunction. Multiple studies have confirmed that even mild FMR portends ...
Mosquera Victor X VX Department of Cardiac Surgery, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain. Electronic address: - - 2014
The present study aimed to identify potential differences in hemodynamic performance between the supra-annular CarboMedics Top Hat valve and the intra-annular CarboMedics standard valve in terms of the long-term left ventricular mass reduction and transvalvular gradients. We retrospectively reviewed a series of 186 consecutive patients who had undergone aortic valve ...
Karakoyun Süleyman S Department of Cardiology, Koşuyolu Kartal Heart Training and Research Hospital, İstanbul, Turkey. - - 2014
Coronary thromboembolism is a rare cause of acute coronary syndromes (ACS). The information regarding ACS in patients with prosthetic heart valves is scarce and based mainly on case reports. Although plaque rupture is the most common cause of acute myocardial infarction, coronary embolism (CE) is not a rare cause of ...
van Rosendael Philippe J PJ Department of Cardiology, Leiden University Medical Center, Leiden, The - - 2014
The underlying mechanism of mitral regurgitation (MR) because of isolated annulus dilation (Carpentier type I) remains controversial in patients with atrial fibrillation (AF). The present study evaluated changes in mitral valve geometry of patients with AF and structurally and functionally normal left ventricles and mitral leaflets. Grade of MR and ...
Tayama Eiki - - 2014
A 75-year-old man (Asian, Japanese) was readmitted for examination of a heart murmur and haemolytic anemia 3 months after mitral valve and tricuspid annuloplasties and coronary artery bypass. A new systolic murmur was heard, and echocardiography showed a high-velocity jet originating from the left ventricular outflow tract and extending to ...
Masoumi Nafiseh N Biomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 65 Landsdowne Street, Cambridge, MA 02139, USA; Department of Cardiac Surgery, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA; Department of Bioengineering, The Pennsylvania State University, 205 Hallowell Building, State College, PA 16802, USA; Harvard-MIT Division of Health Sciences and Technology and The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, - - 2014
Tissue engineered heart valves (TEHVs) that can grow and remodel have the potential to serve as permanent replacements of the current non-viable prosthetic valves particularly for pediatric patients. A major challenge in designing functional TEHVs is to mimic both structural and anisotropic mechanical characteristics of the native valve leaflets. To ...
Kurihara Chitaru C Department of Cardiac Surgery, Tokyo Metropolitan Geriatric Hospital, 35-2, Sakae-cho, Itabashi-ku, Tokyo, 173-0015, - - 2014
Compact counterpulsation (CP) is a novel external counterpulsation system. The preoperative clinical utility of compact CP therapy in patients has not been established. In the present report, we describe a case wherein compact CP therapy was successfully used to treat severe ischemic heart failure. A 70-year-old man was diagnosed with ...
Cagli Kerim K Department of Cardiovascular Surgery (Drs. Cagli and Lafci), Turkiye Yuksek Ihtisas Hospital, 06100 Ankara; Department of Cardiovascular Surgery (Dr. Cagli), Hitit University, 19000 Corum; and Department of Cardiovascular Surgery (Drs. Budak, Gedik, Korkmaz, and Yener), Ankara Numune Research and Education Hospital, 06100 Ankara; - - 2014
Transventricular mitral valve surgery combined with left ventricular restoration avoids atriotomy and provides a larger operative field. We describe a series of 5 patients in whom we performed transventricular mitral valve repair by various techniques, such as band annuloplasty, papillary muscle reattachment, chordal cutting, and edge-to-edge repair. The more acute ...
Booker Oscar J OJ Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, - - 2014
Ebstein's anomaly is a complex congenital lesion which primarily involves the tricuspid valve. The tricuspid leaflets are tethered to varying degrees to the right ventricular free wall and the ventricular septum often resulting in significant tricuspid regurgitation and a small functioning right ventricular chamber. Although the septal leaflet originates normally ...
Ushijima Tomoki T Department of Cardiovascular Surgery, Aso Iizuka Hospital, 3-83 Yoshio-machi, Iizuka, Fukuoka, 820-8505, - - 2014
The 16-mm ATS mechanical valve is one of the smallest prosthetic valves used for aortic valve replacement (AVR) in patients with a very small aortic annulus, and its clinical outcomes are reportedly satisfactory. Here, we analyzed the left ventricular (LV) performance after AVR with the 16-mm ATS mechanical valve, based ...
Silbiger Jeffrey J JJ Icahn School of Medicine at Mount Sinai, New York, New - - 2014
Papillary muscle repositioning due to left ventricular remodeling is thought to be the primary mechanism responsible for functional mitral regurgitation. This article proposes that remodeling (enlargement) of the left atrium also plays a role in the pathogenesis of functional mitral regurgitation, through a novel mechanism-atriogenic leaflet tethering-described herein.
Olmos Carmen C Instituto Cardiovascular, Hospital Clínico San Carlos, Madrid, Spain. Electronic address: - - 2014
Native valve infective endocarditis (IE) in patients with normal valves has increased in the last decades. Whether patients with normal valves present a similar prognosis to those with pathologic valves is unresolved. Our aim is to describe epidemiologic and clinical differences between patients with left-sided IE and normal valves and ...
Agarwal Sanjeev Kumar SK Cardiology, Rashid Hospital, Dubai, UAE. Electronic address: - - 2014
Dual antiplatelet therapy including aspirin and a P2Y12 ADP receptor antagonist is given after percutaneous coronary intervention to avoid catastrophic complication of stent thrombosis. Dual antiplatelet therapy is associated with increased bleeding risk and may not be tolerated by many patients. This article presents the patients, which had to be ...
Kumar Vipin V Assistant Professor, Department of Cardiology, Christian Medical College Hospital, Vellore 632004, Tamil Nadu, India. Electronic address: - - 2014
62-Year-old female presented with progressive dyspnea NYHA class III for six months. Echocardiography showed normal left ventricular (LV) systolic function, mild biatrial enlargement, an L wave in pulse wave Doppler at mitral inflow and in M mode echocardiography across mitral valve. Tissue Doppler imaging at medial mitral annulus showed an ...
Eslami Maryam M 1Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, - - 2014
Heart valve-related disorders are among the major causes of death worldwide. Although prosthetic valves are widely used to treat this pathology, current prosthetic grafts cannot grow with the patient while maintaining normal valve mechanical and hemodynamic properties. Tissue engineering may provide a possible solution to this issue through using biodegradable ...
Radwan-Oczko Małgorzata M Department of Periodontology; Unit of Oral Pathology; Wroclaw Medical University; Wroclaw, - - 2014
Background There is evidence that advanced infectious chronic periodontal inflammatory disease may have an impact on general health including cardiovascular diseases. The aim of this clinical study was to evaluate the ability of Porphyromonas gingivalis to colonize heart valves and, subsequently, to assess whether there is an association between the ...
Kandasamy Ashok A Department of Cardiothoracic Anesthesia, SRM Medical College Hospital and Research Centre, SRM University, Chennai, Tamil Nadu, - - 2014
We describe postoperative refractory ventricular tachycardia (VT) in a patient following aortic and mitral valve replacement. Following an uneventful separation from cardiopulmonary bypass with dobutamine, the patient developed recurrent VT, 4 hours into the postoperative period. The VT did not respond to standard doses of xylocard, magnesium and amiodarone. Electrolyte ...
Ayers Jennifer J Department of Cardiology (Drs. Ayers, Hsi, Mandell, and Sanghvi), and Division of Infectious Disease (Dr. Aboujaoude), Deborah Heart & Lung Hospital, Browns Mills, New Jersey - - 2014
The human immunodeficiency virus (HIV) can cause diverse cardiovascular complications. In HIV patients on antiretroviral therapy, the prevalence of myocardial infarction has steadily increased over the years. Young patients who are naïve to antiretroviral therapy and who experience coronary events are not well represented in the medical literature. We describe ...
Wani Mohd Lateef ML Department of Cardiovascular and Thoracic Surgery, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, - - 2014
The interest in beating heart surgery is growing since better results can be obtained with this procedure compared to conventional myocardial protection techniques using cardioplegic solutions. This led us to consider mitral valve replacement with beating heart. This study aimed to determine the safety and efficacy of beating heart mitral ...
Rantala Sari - - 2014
Cardiac device-related endocarditis is a very rare clinical manifestation of S. dysgalactiae subsp. equisimilis disease. This pathogen is a common cause of cellulitis. We here report two cases of cardiac device-related endocarditis due to Streptococcus dysgalactiae subsp. equisimilis. Blood cultures yielded this pathogen and both patients had recurrent bacteremia. Transthoracic ...
Jana S S Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, - - 2014
Tissue engineered heart valves offer a promising alternative for the replacement of diseased heart valves avoiding the limitations faced with currently available bioprosthetic and mechanical heart valves. In the paradigm of tissue engineering, a three-dimensional platform - the so-called scaffold - is essential for cell proliferation, growth, and differentiation as ...
Nakamura Yuki Y Department of Cardiovascular Surgery, Ehime University Hospital, Shitsukawa, Toon, Ehime, 791-0295, Japan, - - 2014
Hereditary hemorrhagic telangiectasia (HHT) is caused by an autosomal dominant gene and characterized by multiple arteriovenous malformations in several organs, leading to bleeding or shunting. These patients often suffer severe infections and heart failure, which should be managed in the perioperative period, when open heart surgery is indicated. We report ...
Abhaichand Rajpal K RK Department of Cardiology, GKNM Hospital, Coimbatore, - - 2014
Balloon mitral valvotomy is a commonly performed procedure for mitral stenosis. This procedure can lead to complications such as left ventricular perforation with tamponade, mitral regurgitation and stroke. Here we report a case of left ventricular pseudoaneurysm following balloon mitral valvotomy. It was a consequence of adherent pericardium secondary to ...
Fiedler K A - - 2014
There is little evidence on the optimal mode of clopidogrel discontinuation. Epidemiological studies observed clustering of thrombotic events after cessation of chronic clopidogrel therapy. The underlying mechanism has been ascribed to transient platelet hyper-reactivity. Gradual tapering of clopidogrel may have the potential to attenuate this phenomenon. The objective of the ...
Nozohoor Shahab S Department of Cardiothoracic Surgery, Anesthesia and Intensive Care, Skane University Hospital, Lund University, Lund, - - 2014
Several types of valves and valved conduits have been developed for right ventricular outflow tract reconstruction and yet no one has provided prolonged satisfactory hemodynamic performance. The RVOT Elan is a bioprosthetic heart valve conduit constructed from a vascular graft and a porcine stentless valve indicated specifically for right ventricular ...
Weinstein Jean Marc JM Cardiology Department, Soroka University Medical Center, PO Box 151, Beer-Sheva, Israel. - - 2014
There is much debate on the pathogenesis of ischemic mitral regurgitation (MR), usually related to global or regional left ventricular dysfunction or remodeling secondary to chronic ischemic changes, altering the tethering and closing forces on the mitral apparatus. There is a paucity of literature describing MR in the setting of ...
Ye Ying Y Cleveland Clinic Lerner College of Medicine, Cleveland, - - 2014
The study objective was to investigate whether, in patients undergoing surgery for degenerative mitral valve disease, associated right ventricular remodeling and dysfunction are stronger determinants of preoperative organ dysfunction and prognosis than functional tricuspid regurgitation. From January 2001 to January 2011, 4197 patients underwent primary mitral valve surgery for degenerative ...
Agricola Eustachio - - 2014
The study aim was to evaluate whether, in patients with severe mitral regurgitation (MR), tricuspid valve remodeling was independent of the degree of functional tricuspid regurgitation (FTR) present. Whether any differences in the analysis remodeling, as assessed by two-dimensional (2D) and three-dimensional (3D) echocardiography, can be demonstrated was also addressed. ...
Fujita Tomoyuki T Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Centre, Osaka, - - 2014
Although right heart failure (RVF) is an important issue in the management of patients with left ventricular assist devices (LVADs), the benefits of performing tricuspid valve repair in conjunction with LVAD implantation have not been demonstrated. We retrospectively reviewed the records of 141 patients who received LVAD implantation as a ...
Deja Marek A MA 2nd Department of Cardiac Surgery, Medical University of Silesia, Katowice, - - 2014
It remains unclear why some patients with cardiomyopathy secondary to anterior infarction do, and others do not develop functional mitral regurgitation (MR). Thirty-six patients after anterior infarction with ejection fraction (EF) of below 35%, 18 with no/trivial and 18 with moderate/severe MR, underwent cardiac magnetic resonance imaging. Parameters describing the ...
Tanaka Daizo D Daizo Tanaka, Shinya Unai, James T Diehl, Hitoshi Hirose, Division of Cardiothoracic Surgery, Department of Surgery, Thomas Jefferson University, Philadelphia, PA 19107, United - - 2014
Left ventricular (LV) thrombus is a life-threatening complication of severe LV dysfunction. Ventriculotomy has been a commonly performed procedure for LV thrombus; however, it often further decrease LV function after surgery. We present an alternative approach to thrombectomy in order to minimize the postoperative LV dysfunction. A 37-year-old female with ...
Adelstein Evan E Heart and Vascular Institute, Cardiology Department, University of Pittsburgh Medical Center, Pittsburgh, - - 2014
Echocardiography-guided left ventricular (LV) lead placement at the site of latest mechanical activation improves heart failure outcomes in patients receiving a cardiac resynchronization therapy defibrillator (CRT-D). In this study, we test the hypothesis that a strategy of echocardiography-guided LV lead placement improves patient survival rate free from appropriate CRT-D therapy ...
Adriaanse B M E BM Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The - - 2014
The differential insertion of the atrioventricular valves is the ultrasonographic representation of the more apical attachment of the tricuspid valve to the septum with respect to the mitral valve. A linear insertion is present when both valves form a linear continuum and is suggested as a marker for atrioventricular septal ...
Zeng Xin X Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Boston, - - 2014
Ischemic mitral regurgitation (IMR) results from mitral leaflet tethering from left ventricular remodeling. Heterogeneity in local or global left ventricular remodeling can result in differential tethering patterns and affect mitral valve function and the degree of mitral regurgitation. The aims of this study were to compare mitral valve geometry in ...
Van Nooten Guido J GJ Department of Cardiac Surgery, University of Ghent, Ghent, Belgium. Electronic address: - - 2014
Since May 1992 the Medtronic Open Pivot mechanical heart valve has been implanted routinely at the authors' institution. The study aim was to analyze, retrospectively, the 20-year clinical results of the valve. Between May 1992 and December 2011 a total of 1,520 valves was inserted into 1,382 consecutive patients (1,012 ...
Wang Tom Kai Ming TK Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand. Electronic address: - - 2014
Right heart endocarditis makes up 5-10% of all infective endocarditis involving valvular, congenital and artificial structures. Given the limited literature in this area, we reviewed the characteristics, management and outcomes of this condition in this retrospective cohort study. Thirty-five patients with right heart endocarditis admitted to Auckland City Hospital during ...
Esposito Giampiero G Department of Cardiac Surgery, Humanitas Gavazzeni Hospital, Bergamo, - - 2014
Tethering of both mitral leaflets is the predominant mechanism of mitral regurgitation in patients with chronic ischaemic cardiomyopathy. For patients with severe mitral leaflet tethering, we have developed a surgical approach alternative to the conventional undersized annuloplasty ring that targets the subvalvular apparatus and aims to reconstitute the leaflet coaptation ...
Adigopula Sasikanth - - 2014
ACC Stage C heart failure includes those patients with prior or current symptoms of heart failure in the context of an underlying structural heart problem who are primarily managed with medical therapy. Although there is guideline-based medical therapy for those with heart failure with reduced ejection fraction (HFrEF), therapies in heart ...
Parry Dominic D Department of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, Ontario, Canada. Electronic address: - - 2014
Aortic valve disease in the setting of a left ventricular assist device presents unique challenges. We present the case of a patient who underwent transcatheter aortic valve implantation to replace a stenotic aortic valve to facilitate left ventricular assist device explantation. Thirty-three days later, the porcine pericardial valve cusps were ...
Abdallah Mouin S MS Saint Luke's Mid America Heart Institute, Kansas City, Missouri; University of Missouri-Kansas City, Kansas City, Missouri. Electronic address: - - 2014
Intensive statin therapy is a central component of secondary prevention after acute myocardial infarction (AMI), particularly among high-risk patients, such as those with diabetes mellitus (DM). However, the frequency and predictors of intensive statin therapy use after AMI among patients with DM have not been described. We examined patterns of ...
Denti Paolo P San Raffaele University Hospital, Via Olgettina, 60, 20100, Milan, Italy, - - 2014
The natural history of severe mitral regurgitation (MR) is unfavorable, leading to left ventricular failure, atrial fibrillation, stroke, and death. Many patients affected by severe regurgitation (MR) do not currently undergo surgery, mainly due to the perceived risk of the procedure (old age, impaired left ventricular function, and comorbidities). Mitral ...
Masoumi Nafiseh N Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, 65 Landsdowne Street, Cambridge, MA, 02139, USA; Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, MA, 02115, USA; Department of Cardiac, Surgery Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA; Department of Bioengineering, The Pennsylvania State University, 205 Hallowell Building, State College, PA, 16801, - - 2014
Tissue engineered heart valves (TEHV) can be useful in the repair of congenital or acquired valvular diseases due to their potential for growth and remodeling. The development of biomimetic scaffolds is a major challenge in heart valve tissue engineering. One of the most important structural characteristics of mature heart valve ...
Manji Rizwan A RA Department of Surgery, University of Manitoba, Winnipeg, MB, Canada; Cardiac Sciences Program, Winnipeg Regional Health Authority and St. Boniface Hospital, Winnipeg, MB, - - 2014
Glutaraldehyde-fixed bioprosthetic heart valves (GBHVs), derived from pigs or cows, undergo structural valve deterioration (SVD) over time, with calcification and eventual failure. It is generally accepted that SVD is due to chemical processes between glutaraldehyde and free calcium ions in the blood. Valve companies have made significant progress in decreasing ...
Caspar Thibault T Department of Cardiology, University Hospital of Strasbourg, Strasbourg, - - 2014
We report a very rare case of a 43-year-old patient with fatal left ventricular subepicardial aneurysm rupture complicating embolic myocardial infarction due to mitral valve infective endocarditis.
Oueida Farouk F Cardiac Surgery Department, Saud Al-Babtain Cardiac Centre, Dammam, Saudi - - 2014
Atrial fibrillation is the most common form of arrhythmia in mitral valve disease. Radiofrequency ablation is most commonly used for atrial fibrillation ablation during mitral valve surgery. This prospective study evaluated the midterm outcomes of intraoperative radiofrequency atrial fibrillation ablation during mitral valve surgery. 52 patients were eligible for the ...
Xu Sheng-Song SS Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Anhui Medical University, Cardiovascular Disease Research Center of Anhui Medical University, Hefei, - - 2014
Aortic-left ventricular tunnel is a rare congenital cardiac anomaly, which always arises from the right coronary sinus and enters the left ventricle, occasionally the right ventricle and right atrium. However, aortic and left ventricular tunnel associated with infective endocarditis is rarely seen in literatures. Here, we present a case of ...
Punnoose Lynn L Division of Cardiology, Weill Cornell Medical College, New York, NY. Electronic address: - - 2014
Functional mitral regurgitation is a highly prevalent condition among patients with ischemic and dilated cardiomyopathies. Arising from remodeling of both the mitral valve annulus and left ventricle, it is associated with high mortality and morbidity. In select patients, cardiac resynchronization therapy helps reduce functional mitral regurgitation, but surgical intervention remains ...
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