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Results 201 - 250 of 2924
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Muraru Denisa - - 2012
Integrating volumetric rendering with motion in real-time, three-dimensional (3D) echocardiography is the most suitable imaging technique for assessing heart valves. Today, the rapidly advancing 3D technology allows us to perform a virtual 'dissection' of the heart intra vitam and to discover unprecedented, realistic views of cardiac valves in just a ...
Chidambaram Sundar S Madras Medical College, Chennai, India. - - 2013
Left atrial thrombus in the presence of diseased mitral valve and atrial fibrillation is a well known entity. But it is very rare to occur in the presence of normal mitral valve apparatus. We report the case of a 36 year old female who presented with left atrial ball valve ...
Hosono Mitsuharu - - 2012
Purpose: Few recent studies have examined the long-term outcomes after aortic valve replacement (AVR), and independent predictors for long-term survival and valve-related mortality have not been elucidated.Methods: From January 1993 to December 2009, 132 elderly patients (≥70 years old) with aortic stenosis underwent AVR in our hospital. The patients comprised ...
Bonow Robert O - - 2012
The timing of surgery in patients with mitral regurgitation (MR) and aortic regurgitation (AR) continues to elicit uncertainty and considerable controversy. Some patients will incur myocardial structural changes, pulmonary hypertension, or arrhythmias before they manifest symptoms, with the risk that these adverse endpoints will not be reversible after valve repair ...
Tiong Ing S - - 2012
ST-elevation myocardial infarction from coronary embolus is a rare complication of nonbacterial thrombotic endocarditis, with little data on therapeutic management. We present a novel use of percutaneous coronary aspiration thrombectomy using an Export(®) catheter resulting in successful restoration of normal coronary blood flow. We also demonstrated complete resolution of the ...
Lamas Cristiane da Cruz - - 2012
PCR was used to detect Coxiella burnetii and Bartonella spp in heart valves obtained during the period 1998-2009 from patients operated on for blood culture-negative endocarditis in a cardiac surgery hospital in Brazil. Of the 51 valves tested, 10 were PCR-positive; two were positive for Bartonella and one for C. ...
Ghosh B D - - 2012
Treatment of acute ST-elevation myocardial infarction (STEMI) has rapidly evolved with many advances made in the past decade. Percutaneous coronary intervention is the preferred strategy when available, although there remains a role for thrombolytic therapy, with prompt reperfusion as the primary goal. With regards to antithrombotic therapy, bivalirudin now has ...
Dobesh Paul P - - 2012
Approximately 1.2 million people are hospitalized annually for acute coronary syndrome (ACS) in the United States, with direct medical costs estimated at $150 billion in 2009. Rehospitalization is common, often as the result of recurrence of the initial event or complications of ACS or its therapy. Thrombosis is central to ...
Zhang Wei - - 2012
We here present the case of a 35-year-old man with mitral valve paravalvular abnormal tunnel with mitral regurgitation caused by anterior chest trauma. The abnormal tunnel is between left ventricular and left artrial. We sutured the tunnel with a patch from the left atrial side. Meanwhile, we performed the mitral ...
Ugaki Shinya - - 2012
OBJECTIVE: Tricuspid regurgitation is a significant risk factor for reoperation and mortality in patients with hypoplastic left heart syndrome. The effects of tricuspid valve repair on quantitative measures of right ventricle and tricuspid valve remodeling have not been well documented. METHODS: We reviewed retrospectively the 2-dimensional echocardiograms of 17 tricuspid ...
Elbey M A - - 2012
<strong> </strong> Interatrial duration is defined as prolonged p wave on electrocardiogram. p waves with a negative terminal phase recorded in V1 enclosing an area of one small square on the electrocardiogram is significantly and strongly correlated with interatrial duration. The aim of study was to investigate whether interatrial duration ...
Mathias Helen - - 2012
Accessory mitral valve tissue is an uncommon congenital malformation and a rare cause of left ventricular outflow tract obstruction. Although echocardiography provides a "gold standard" for evaluation of valves, the high temporal and spatial resolutions of computed tomography technology makes it useful in the assessment of valvular structure and function.
Benjo Alexandre M - - 2012
ABSTRACT: Herein, we report a case of a 39-year-old woman with an 18-month history of peripartum cardiomyopathy. Transthoracic echocardiography revealed severe functional mitral regurgitation and a left ventricular ejection fraction of 20%. Despite optimal medical therapy, she was in New York Heart Association heart failure class IV, with dyspnea on ...
Sugimura Yukiharu - - 2012
A 52-year-old man was referred to our clinic because of chronic heart failure. A Levine 3/6 diastolic heart murmur was audible at the apex. Chest radiography showed an enlarged left ventricle. Transthoracic echocardiography showed moderately severe aortic regurgitation. Left ventricular end-diastolic/systolic diameter and ejection fraction were 75/59 mm and 41 %, respectively. ...
Ohishi Sugiko - - 2012
A 31-year-old woman complained of dyspnea and orthopnea at 38 weeks of gestation. A grade 3/6 pansystolic murmur was heard, and echocardiography revealed severe mitral regurgitation with a hyperechoic obstacle on the posterior mitral valve leaflet, consistent with a diagnosis of acute heart failure due to a ruptured chordae tendineae ...
Siefert Andrew W AW The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Ga, - - 2013
Forces acting on mitral annular devices in the setting of ischemic mitral regurgitation are currently unknown. The aim of this study was to quantify the cyclic forces that result from mitral annular contraction in a chronic ischemic mitral regurgitation ovine model and compare them with forces measured previously in healthy ...
Poh Kian-Keong - - 2012
BACKGROUND: The presence of ischemic mitral regurgitation (IMR) after ST-segment elevation myocardial infarction (STEMI) portends a poorer prognosis. The possible influence of reperfusion therapy in restoring mitral valve competence in inferoposterior STEMI has not been well elucidated. METHODS AND RESULTS: We studied 423 consecutive patients with a first inferoposterior STEMI ...
Monaghan Michael - - 2012
A complex cascade of genomic and proteomic interactions follows myocardial infarction (MI) irrespective of the intervention employed. A potential pharmacological intervention gaining momentum is RNAi therapy. RNAi therapy has been successfully clinically used in the treatment of age-related macular degeneration and cancer, but its translation to the coronary care unit ...
Grimm W - - 2012
Arrhythmia risk stratification with regard to prophylactic implantable cardioverter-defibrillator (ICD) therapy was investigated in the Marburg Cardiomyopathy Study, which revealed left ventricular ejection fraction to be the only significant independent arrhythmia risk predictor in a relatively large dilated cardiomyopathy (DCM) patient population. Based of the favorable results of the SCD-HeFT ...
Moore J T - - 2012
Traditional surgical approaches for repairing diseased mitral valves have relied on placing the patient on cardiopulmonary bypass (on pump), stopping the heart and accessing the arrested heart directly. However, because this approach has the potential for adverse neurological, vascular and immunological sequalae, less invasive beating heart alternatives are desirable. Emerging ...
Koppers Gille - - 2012
©2012 Wiley Periodicals, inc. Current guidelines recommend tricuspid valve annuloplasty (TVP) together with mitral valve surgery in cases of tricuspid annulus dilation (≥40 mm) or functional tricuspid valve regurgitation >2/4. Baseline clinical and echocardiographic data of patients undergoing mitral valve surgery in a single tertiary care hospital between 2007 and 2010 ...
Fiorelli A I - - 2012
Tricuspid regurgitation (TR) is the most commonly valvular dysfunction found after heart transplantation (HTx). It may be related to endomyocardial biopsy (EMB) performed for allograft rejection surveillance. This investigation evaluated the presence of tricuspid valve tissue fragments obtained during routine EMB performed after HTx and its possible effect on short-term ...
Akin Ibrahim I - - 2012
ABSTRACT: BACKGROUND: Nonagenarians are mostly denied from different therapeutic strategies due to high comorbidity index and risk-benefit calculation. We present the results of nonagenarians with high comorbidity index not eligible for conventional aortic valve surgery undergoing transcatheter aortic valve implantation (TAVI) with the CoreValve system. METHODS: Our retrospective analysis include ...
Desai Ravi R - - 2012
OBJECTIVES: To study the effect of mitral valve repair with or without concomitant tricuspid valve repair on functional tricuspid regurgitation and right ventricular function. METHODS: From 2001 to 2007, 1833 patients with degenerative mitral valve disease, a structurally normal tricuspid valve, and no coronary artery disease underwent mitral valve repair, ...
Altiok Ertunc - - 2012
BACKGROUND: -Analysis of procedural effects in patients undergoing percutaneous mitral valve edge-to-edge repair (PMVR) is complex and common techniques to define mitral regurgitation severity based on 2-dimensional (2D) echocardiography are not validated for post procedural double-orifice mitral valve. This study used 3-dimensional (3D) transesophageal echocardiography (TEE) to determine functional and ...
Watts As - - 2012
Abstract CASE HISTORY: A 10-year-old Friesian dairy cow presented with a history of weight loss, decreased milk production and fluid splashing on auscultation of the heart. Previous antibiotic therapy included oxytetracycline, marbofloxacin and penicillin. CLINICAL AND PATHOLOGICAL FINDINGS: Following a failure to respond to treatment, prescribed by the referring veterinarian ...
Drighil Abdenasser - - 2012
BACKGROUND: Functional analysis of the right ventricle cannot be reliably evaluated by conventional echocardiography, because of its complex geometry and load dependence of ejection phase indices. The Tei index, dP/dt, and myocardial acceleration during isovolumic contraction are parameters of right ventricular (RV) contractility unaffected by RV geometry. However, the effect ...
Askov Jesper B - - 2012
OBJECTIVE: The objective of this study was to assess the combined force transfer from the papillary muscle tips to the mitral valve through the chordae tendineae in vivo, and thereby quantify the force transmitted through the papillary-chordal complex to augment left ventricular ejection. METHODS: In an acute porcine model (n = 8), force ...
Levack Melissa M - - 2012
Proponents of flexible annuloplasty rings have hypothesized that such devices maintain annular dynamics. This hypothesis is based on the supposition that annular motion is relatively normal in patients undergoing mitral valve repair. We hypothesized that mitral annular dynamics are impaired in ischemic mitral regurgitation and myxomatous mitral regurgitation. A Philips ...
Otani Kyoko K Second Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, - - 2012
In patients with mitral valve prolapse, nonprolapsed leaflets are often apically tented. We hypothesized that secondary left ventricular dilatation attributed to primary mitral regurgitation (MR) causes papillary muscle (PM) displacement, resulting in this leaflet tenting/tethering, and that secondary tethering further exacerbates malcoaptation and contributes to MR severity. Three-dimensional transesophageal echocardiography ...
Jackson Shaun P - - 2012
Antiplatelet agents have become the cornerstone pharmacological therapy for the acute coronary syndromes (ACS). Used in combination with percutaneous coronary intervention, antithrombotic therapy has had a major positive impact on outcomes in this patient group [1-3]. The relatively high frequency of recurrent thrombosis with single antiplatelet therapy has necessitated the ...
Gatti Giuseppe - - 2012
Chronic ischemic mitral regurgitation (IMR) is associated with asymmetric mitral leaflet tethering and annular dilation. The Carpentier-McCarthy-Adams IMR ETlogix annuloplasty ring is designed specifically to treat these asymmetric pathological changes. In the present study, the results of mitral annuloplasty with this ring in a selected subset of patients with significant ...
Overend Louise - - 2012
Embolic myocardial infarction is an uncommon but increasingly recognised complication of infective endocarditis. This complication has a high mortality rate and is deemed a relative contraindication to thrombolytic therapy. The present article describes an episode of acute myocardial infarction associated with infective endocarditis. Systemic thrombolytic therapy was administered, which resulted ...
McCann Patrick - - 2012
Inotropic therapy remains an option in the management of patients with advanced heart failure symptoms from systolic dysfunction who do not respond to conventional therapies. The decision to use this class is largely predicated on an accurate evaluation of the patient's fluid and perfusion status. Selection of the appropriate agent ...
Bochard-Villanueva Bruno - - 2012
Acquired left ventricular-right atrial communication ( Gerbode-type defect) is a rare complication of infective endocarditis. Although transesophageal echocardiography remains the technique of choice for the evaluation of complications of endocarditis this case highlights the usefulness of cardiac computed tomography in this scenario, particularly in cases where assessment of coronary anatomy ...
Quick Esther - - 2013
Mitral valve annulus calcification is a degenerative cardiac condition often found at autopsy in the elderly. While usually considered incidental to the cause of death, we report two cases where mitral valve annulus calcification with valve stenosis was associated with sudden death. Case 1: a 61-year-old female who had underlying ...
Tong Betty C BC Division of Thoracic and Cardiovascular Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA. - - 2012
Coronary revascularization trials often use a composite endpoint of major adverse cardiac and cerebrovascular events (MACCE). The usual practice in analyzing data with a composite endpoint is to assign equal weights to each of the individual MACCE elements. Noninferiority margins are used to offset effects of presumably less important components, ...
Beauchamp-Irizarry Ana - - 2012
Despite improvements in care, up to one-third of patients presenting with ST-elevation myocardial infarction (STEMI) within 12 hours of symptom onset receive no reperfusion therapy. Despite effective pre- and in-hospital reperfusion strategies becoming standard over the past two decades, time-to-admission and time-to-treatment remains prolonged. Prompt reperfusion treatment is essential to ...
Demir Fikri - - 2012
Left ventricular noncompaction (LVNC) is a rare cardiomyopathy. It usually presents with ventricular dysfunction, thromboembolic events and arrhythmias. An asymptomatic clinical course is also possible. LVNC is frequently associated with other congenital heart diseases including heart valve abnormalities. The coexistence of LVNC with double-orifice mitral valve was observed rarely. The ...
Grothoff Matthias M Department of Diagnostic and Interventional Radiology, University of Leipzig-Heart Center, Struempellstrasse 39, Leipzig, Germany. - - 2013
Patients with a congenitally corrected transposition of the great arteries show an increasing incidence of cardiac failure with age. In other systemic right ventricles, such as in dextro-transposition after atrial switch, excessive hypertrophy is a potential risk factor for impaired systolic function. In this trial, we sought to compare systemic ...
Bonou Maria - - 2012
Prosthetic valve thrombosis is a potentially life-threatening complication associated with high morbidity and mortality. Transthorasic and transoesophageal echocardiography play an important role to the diagnosis and provides incremental information about the optimal treatment strategy, while fluoroscopy and cardiac computed tomography may be of added value. Guidelines differ on whether surgical ...
Karantalis Vasileios - - 2012
Although pharmacological and interventional advances have reduced the morbidity and mortality of ischemic heart disease, there is an ongoing need for novel therapeutic strategies that prevent or reverse progressive ventricular remodeling following myocardial infarction, the process that forms the substrate for ventricular failure. The development of cell-based therapy as a ...
Carrick Richard R College of Medicine of the University of Vermont, Burlington, Vermont, - - 2012
We sought to determine regional myofiber stress after Coapsys device (Myocor, Inc, Maple Grove, MN) implantation using a finite element model of the left ventricle (LV). Chronic ischemic mitral regurgitation is caused by LV remodeling after posterolateral myocardial infarction. The Coapsys device consists of a single trans-LV chord placed below ...
Pantin Enrique J - - 2012
To perform minimally invasive cardiac surgery through the smallest possible wound and with the least number of incisions in the heart or aorta, the necessary cannulations to undergo cardiopulmonary bypass must be done through peripheral vessels. A difficult skill to learn for the cardiac anesthesiologist is how to safely and ...
Kortsmit Jeroen - - 2012
An emerging therapy to limit adverse heart remodelling following myocardial infarction (MI) is the injection of polymers into the infarcted left ventricle (LV). In the few numerical studies carried out in this field, the definition and distribution of the hydrogel in the infarcted myocardium were simplified. In this computational study, ...
Rady Mohamed Y - - 2012
Left ventricular assist devices (LVADs) and total artificial hearts (TAHs) are surgically implanted as permanent treatment of unrecoverable heart failure. Both LVADs and TAHs are durable mechanical circulatory support (MCS) devices that can prolong patient survival but also alter end-of-life trajectory. The permissibility of discontinuing assisted circulation is controversial because ...
Loor Gabriel - - 2012
Temporary right ventricular (RV) support is considered during insertion of a left ventricular assist device in patients who are at risk of right ventricular dysfunction. There are several circuits and cannulation strategies available. Here, we report an effective and safe method for achieving RV support using the RotaFlow (Maquet) extracorporeal ...
Boccaccio Antonio - - 2012
Abstract Left ventricular assist devices (LVADs) work as a bypass between the left ventricular apex and the ascending aorta. The surgical procedure for their insertion requires the opening of the cardiac cavities and the dissection of the great vessels, the blood is constrained to flow through the device components and ...
Dolla William Jacob S - - 2012
Thin cap fibroatheroma (TCFA) in coronary arteries is believed to be associated with plaque rupture leading to cardiovascular death and non-fatal myocardial infarction. Catheter-based imaging platforms can identify TCFAs but detection algorithms lack specificity. Here we report results of an exploratory study of the variability in TCFA plaque attributes and ...
Ashikaga H - - 2012
The aim of the present study was to validate area change ratio (%AC) against myofiber shortening (%ë f) in the heart in vivo. %AC is emerging as a mechanical index that may approximate %ë f by incorporating both circumferential and longitudinal shortening. However, the physiological significance of %AC remains unclear. ...
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