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Choi Andrew D - - 2013
The case is reported of a patient with a previously undiagnosed cause of severe congestive heart failure (CHF) caused by the presence of a discrete subaortic stenosis (SAS) from a subvalvular membrane (SVM). The clinical decision making was complicated by the concurrent presence of systolic anterior motion (SAM) of the ...
Weber Benedikt - - 2013
Heart valve tissue engineering based on decellularized xenogenic or allogenic starter matrices has shown promising first clinical results. However, the availability of healthy homologous donor valves is limited and xenogenic materials are associated with infectious and immunologic risks. To address such limitations, biodegradable synthetic materials have been successfully used for ...
Martina Jerson R JR Department of Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, - - 2013
Continuous-flow left ventricular assist devices (cf-LVADs) may induce commissural fusion of the aortic valve leaflets. Factors associated with this occurrence of commissural fusion are unknown. The aim of this study was to examine histological characteristics of cf-LVAD-induced commissural fusion in relation to clinical variables. Gross and histopathological examinations were performed ...
Yoganathan Ajit P - - 2013
Congenital heart valve disease is one of the most common abnormalities in children. There are limited technological solutions available for treating children with congenital heart valve diseases. The aim of this study is to provide the details of the consensus reached in terms of pediatric definitions, design approach, in vitro testing, ...
Yang Zhaoying - - 2013
OBJECTIVE: To investigate vascular endothelial impairment as a result of reperfusion therapy in patients with acute myocardial infarction (AMI). METHODS: Patients with AMI underwent reperfusion therapy (percutaneous cardiac intervention [PCI] or thrombolytic therapy) or conservative drug therapy. Healthy control subjects were recruited. Endothelial impairment was assessed via endothelial nitric oxide ...
Maltais Simon - - 2013
OBJECTIVES: Patients with severe ischemic cardiomyopathy (left ventricular ejection fraction <25%) and severe ischemic mitral regurgitation have a poor survival with medical therapy alone. Left ventricular assist device as destination therapy is reserved for patients who are too high risk for conventional surgery. We evaluated our outcomes with conventional surgery ...
Mohite Prashant Nanasaheb - - 2013
Diseased, replaced or repaired mitral valve can lead to restricted blood flow to left ventricle and inadequate flow in left ventricular assist device (LVAD). A middle age woman with 'burnt out' hypertrophic cardiomyopathy had mitral valve repair for mitral regurgitation. She needed (LVAD) to support severe decompensating heart failure. Repaired ...
Puri Shipra - - 2013
PURPOSE:: To evaluate the functional capacity following mitral valve replacement in the early postoperative period and to determine the correlation of biventricular function and residual pulmonary artery hypertension (PAH) to the functional capacity. METHODS:: On the seventh postoperative day, 53 patients who underwent mitral valve replacement with preoperative diagnosis of ...
Acioli Pereira Larissa - - 2013
Pseudoaneurysm of the left ventricular outflow tract (LVOT) is a rare disease with high morbidity and mortality, resulting from left ventricular damage due to myocardial infarction, infective endocarditis or surgical trauma. A case of giant pseudoaneurysm of the LVOT, even more rarely reported in the literature, is described. The lesion ...
Connell John M - - 2013
Ischemic mitral regurgitation (IMR) is a subcategory of functional rather than organic, mitral valve (MV) disease. Whether reversible or permanent, left ventricular remodeling creates IMR that is complex and multifactorial. A comprehensive TEE examination in patients with IMR may have important implications for perioperative clinical decision making. Several TEE measures ...
Patel Nirav - - 2013
Robotic surgery is a growing subspecialty in cardiac surgery. Custodiol HTK cardioplegia offers long-term myocardial protection, decreased metabolism, and eliminates multiple cardioplegia dosing. This article reviews the technique, strategy, and considerations for use of Custodiol HTK for myocardial protection in robotic mitral valve surgery.
Pande Shantanu S Department of Cardiovascular and Thoracic Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, - - 2013
asymptomatic left atrial enlargement is not uncommon in rheumatic mitral valve disease. We studied the change in size of the left atrium after mitral valve replacement. between January and December 2005, 116 patients underwent isolated mitral valve replacement. Two groups were identified based on left atrial size: group 1 < 60 mm (n = 79) ...
Bloechlinger Stefan - - 2013
In a patient with staphylococcus lugdunensis prosthetic aortic valve endocarditis and coronary septic embolism accompanied by antero-lateral myocardial infarction, embolic material was successfully aspirated from the bifurcation of the left anterior descending coronary artery and the first diagonal branch. A good angiographic result was documented six months thereafter when the ...
Atsumi Yosuke - - 2013
We report a case of severe mitral regurgitation (MR) with dextrocardia and 180° counterclockwise rotated situs solitus heart. We describe the technique for mitral valve surgery in a patient with dextrocardia and agenesis of the right lung.
Tanrıkulu Azra - - 2013
Studies indicate that 5-7% patients undergoing percutaneous coronary intervention (PCI) have an indication for anticoagulation therapy. Most commonly atrial fibrillation (AF) is the indication. These subjects require triple therapy with aspirin, clopidogrel, and an oral anticoagulant (OAC). Several questions, concerns and challenges exist regarding the duration, benefit, risks and alternatives ...
Cheema Faisal H - - 2013
Valvular heart disease, inherited or acquired, affects more than 5 million Americans yearly. Whereas medical treatment is beneficial in the initial stages of valvular heart disease; surgical correction provides symptomatic relief and long-term survival benefits. Surgical options include either repair or replacement using mechanical or bio-prosthetic valves. Age and need ...
Smadi Othman - - 2013
AIMS: In vitro and in vivo studies were performed to evaluate the diagnostic accuracy of the different Doppler-echocardiographic parameters proposed in the American Society of Echocardiography guidelines to identify dysfunction of bileaflet mechanical valves (BMV) in the aortic position. METHODS AND RESULTS: Two models of BMV (St Jude HP, MCRI ...
Singh Bhupinder - - 2013
The anomalous mitral arcade is a rare congenital malformation of the mitral valve and its tensor apparatus. It is characterized by enlarged papillary muscles connected to each other and to the free edge of the anterior mitral leaflet by a bridge of fibrous tissue. We report a rare variant of ...
Thaden Jeremy - - 2013
A 40-year-old woman from El Salvador presented with 3 months of abdominal pain and diarrhea followed by 2 weeks of atypical chest pain and exertional dyspnea and was diagnosed with eosinophilic endocarditis secondary to Strongyloides stercoralis infection. Transthoracic echocardiogram revealed apical masses in the left and right ventricles and a ...
Varghese Robin - - 2013
OBJECTIVES: We set out to determine if intraoperative pre-bypass transoesophageal echocardiography could assist in predicting which patients are at greatest risk for systolic anterior motion (SAM) after mitral valve repair (MVR). METHODS: Three hundred and seventy-five consecutive patients who underwent reconstructive MVR surgery for degenerative disease were included. Data were ...
Di Mauro Michele - - 2013
This review article focuses on functional tricuspid regurgitation (FTR) that has long been a neglected and underestimated entity. FTR is defined as leakage of the tricuspid valve during systole in the presence of structurally normal leaflets and chordae. FTR may be secondary to several heart diseases, more commonly mitral valve ...
Hung Judy W - - 2013
Mitral regurgitation (MR) is a frequent complication of myocardial infarction and coronary artery disease that is associated with adverse prognosis. The main mechanism of ischemic MR relates to distortion of the spatial relationships between the mitral valve and papillary muscles secondary to ventricular remodeling. The evidence that treatment of ischemic ...
Konecny Tomas - - 2013
Ventricular pacing is most commonly performed at the right ventricular (RV) apex. This is not without risk as placement requires crossing the tricuspid valve (TV) and may cause valvular dysfunction and dyssynchronous activation of the ventricles. The fact that the tricuspid valve lies more apically than the mitral valve allows ...
Rausch Manuel K MK Department of Mechanical Engineering, Stanford University, 496 Lomita Mall, Stanford, CA 94305, USA. - - 2013
Approximately one third of all patients undergoing open-heart surgery for repair of ischemic mitral regurgitation present with residual and recurrent mitral valve leakage upon follow up. A fundamental quantitative understanding of mitral valve remodeling following myocardial infarction may hold the key to improved medical devices and better treatment outcomes. Here ...
Foster Elyse - - 2013
BACKGROUND: -Percutaneous repair of MR permits examination of the effect of MR reduction without surgery and cardiopulmonary bypass on left ventricular (LV) dimensions and function. The goal of this analysis was to determine the extent of reverse remodeling at 12 months following successful percutaneous reduction of mitral regurgitation (MR) with ...
Bilge Mehmet - - 2013
Percutaneous mitral valve repair with the MitraClip is a new promising therapeutic option for symptomatic severe mitral regurgitation (MR). Acute myocardial infarction (MI) is a well-recognized cause of papillary muscle rupture (PMR). If PMR is untreated, the prognosis is poor and the mortality could be as high as 80% during ...
Greque Gilmar V - - 2013
Objective. Evaluate if statin therapy prior to elective coronary stent implantation (CSI) reduces the plasma levels of markers of inflammation and of myocardial necrosis in low-risk stable coronary artery disease patients (CAD). Background. The elevation of markers of inflammation and of myocardial necrosis after percutaneous coronary intervention may interfere with ...
Kortekaas Kirsten A - - 2013
AIMS: Mitral valve repair in patients with functional mitral regurgitation (FMR) has been associated with beneficial left ventricular (LV) reverse remodelling. Recently, galectin-3 emerged as a marker of myocardial inflammation and fibrosis which may influence LV remodelling after surgery. The aim of the current study was to evaluate the association ...
Konerding Moritz A - - 2013
BACKGROUND: The prevalence of mitral regurgitation in cardiac diseases requires annuloplasty systems that can be implanted without excessive patient burden. This study was designed to examine the morphological and functional outcome of a new double helix mitral annuloplasty ring in an ovine model in comparison to the classical Carpentier-Edwards (CE) ...
Udink Ten Cate Floris E A - - 2013
Structural mitral valve (MV) abnormalities are common in patients with hypertrophic cardiomyopathy (HCM). This is the first report demonstrating MV abnormalities in very young children as the sole overt clinical feature of a known HCM-causing sarcomere protein gene mutation. Due to MV leaflet elongation, we also noticed a typical fast ...
Furukawa Kouji - - 2013
A 76-year-old woman with a diagnosis of hypertrophic obstructive cardiomyopathy was referred to our hospital's surgical department. Her echocardiogram revealed diffuse left ventricular hypertrophy, moderate mitral valve regurgitation with systolic anterior motion of the mitral valve, and left ventricular obstruction with a peak outflow gradient of 108 mm Hg. We performed ...
Sawazaki Masaru - - 2013
Giant bilateral atria with mitral and tricuspid regurgitation can cause postoperative respiratory dysfunction. In this article, we describe a case of giant atria with poor respiratory function that was improved by atrial volume reduction. A 79-year-old woman was referred to our institution for valve surgery. Her vital capacity was 1,080 ...
Matyal Robina - - 2013
While percutaneous intervention is an alternative for patients who are not surgical candidates, the rate of morbidity and mortality is comparable to open repair. Appending the reported complications associated with percutaneous intervention (device mal-positioning, dislodgement and entrapment in the sub-valvular apparatus), we report mechanical damage to the tricuspid valve. Percutaneous ...
Miglioranza Marcelo Haertel - - 2013
Tricuspid regurgitation (TR) produced by endocavitary leads (EL) from permanent pacemakers and implantable cardiac defibrillators is a well-known complication of this procedure. The EL may damage or interfere with tricuspid valve function causing mechanical interference of the valve leaflets leading to incomplete valve closure. It is important to recognize this ...
Kim Eun Hee - - 2013
Although transcatheter aortic valve implantation (TAVI) is generally accepted as an alternative or promising treatment option for patients with decompensated cardiovascular disease in an inoperable or high-risk condition, severe hypotension and/or arrhythmia associated with rapid ventricular pacing still poses a challenge to many clinicians. This report describes a 79-year-old patient ...
Bouma Wobbe - - 2013
OBJECTIVES: Papillary muscle rupture (PMR) is a rare, but serious mechanical complication of myocardial infarction (MI). Although mitral valve replacement is usually the preferred treatment for this condition, mitral valve repair may offer an improved outcome. In this study, we sought to determine the outcome of mitral valve repair for ...
Hsuan Chin-Feng - - 2013
BACKGROUND: Ischemic mitral regurgitation (IMR) is common in ischemic heart disease and results in poor prognosis. However, the exact mechanism of IMR has not been fully elucidated. HYPOTHESIS: Quantitation of the mitral tetrahedron using three-dimentianl (3D) echocardiography is capable of evaluating the geometric determinants and mechanisms of IMR. METHODS: Forty ...
Huang Siyao - - 2013
This study presents an image-based finite element analysis incorporating histological photomicrographs of heart valve tissues. We report stress fields inside heart valve tissues, where heterogeneously distributed collagen fibres are responsible for transmitting forces into cells. Linear isotropic and anisotropic tissue material property models are incorporated to quantify the overall stress ...
Huffman Lynn C - - 2013
OBJECTIVE: Mitral valve repair for functional mitral regurgitation is common. Concomitant tricuspid valve repair for associated functional tricuspid regurgitation has gained favor. Controversy exists regarding annuloplasty sizing for tricuspid valve repair. METHODS: Patients with heart failure having functional mitral regurgitation at the University of Michigan and undergoing mitral valve repair ...
Al-Attar Nawwar - - 2013
OBJECTIVES: Left-sided intraventricular remodelling by papillary muscle approximation associated with annuloplasty of the mitral valve improved outcomes for severe functional mitral regurgitation compared with annuloplasty alone. We conceived of, and studied, a papillary muscle sling on the right side of the heart associated with annuloplasty, seeking to reduce tricuspid valve ...
López Javier J Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico Universitario, Valladolid, Spain. Electronic address: - - 2013
There have been no studies conducted in the past that focus on the significance of congestive heart failure in patients with prosthetic valve endocarditis. We studied the incidence of congestive heart failure in patients with prosthetic valve endocarditis and analyzed its profile. In this study, we addressed the prognostic significance ...
Honěk Jakub - - 2013
Left ventricular outflow tract (LVOT) obstruction due to systolic anterior motion of the mitral valve (SAM) occurs in 4-5% of patients after mitral valve repair. If conservative treatment is unsuccessful, reoperation is indicated. Treatment options include repeated mitral valve repair or valve replacement and septal myectomy if hypertrophy is present. ...
Machaalany Jimmy - - 2013
PTOLEMY-2 was a prospective multicenter phase I single-arm feasibility trial to evaluate the second-generation permanent percutaneous transvenous mitral annuloplasty (PTMA) device in reducing functional mitral regurgitation (MR). Percutaneous MR reduction has been performed through a direct method of clipping and securing the mitral leaflets together or an indirect approach of ...
Okada Yukikatsu - - 2013
Mitral annular calcification (MAC) is a fibrous, degenerative calcification of the mitral valve supporting ring and is common in elderly patients. Patients with MAC are older, more likely to be female, and more likely to have higher systolic blood pressure and clinical heart valve disease. MAC is also common among ...
Eleid Mackram F MF Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, - - 2013
To investigate the effect of left ventricular diastolic dysfunction on outcome in patients with mitral stenosis undergoing percutaneous mitral balloon valvotomy (PMBV). We evaluated consecutive patients with mitral stenosis who underwent PMBV from November 1, 2002, through October 30, 2011, at our institution. Of 107 total patients, 35 (32.7%) had ...
Muthiah Kavitha - - 2013
The current recommended anticoagulation regimen during continuous flow centrifugal left ventricular device support is a combination of antiplatelet therapy as well as oral anticoagulation. Despite this, pump thrombosis occurs in rare situations. We report the risk factors and nonsurgical management and outcomes of five patients implanted with continuous flow centrifugal ...
Galper Benjamin Z - - 2013
While dual antiplatelet therapy (DAPT), after percutaneous coronary intervention (PCI) has demonstrated benefit for two important cardiovascular indications, 1) prevention of future myocardial infarction and death following acute coronary syndromes and 2) prevention of stent thrombosis, the optimal duration of treatment with dual antiplatelet therapy after coronary stent placement is ...
Han Dong Cheul - - 2013
Coronary artery embolism is an infrequent cause of acute myocardial infarction. In addition, native aortic valve thrombosis is a very rare condition. We report a case of native valve thrombosis causing acute ST-elevation myocardial infarction in healthy middle-aged man who has no established cardiovascular risk factor. We diagnosed native aortic ...
Rudolph V - - 2013
Mitral regurgitation (MR) is a common complication in heart failure patients, severely worsening their outcome. Because of the high perioperative risk, mitral valve surgery, which is the standard therapy for MR, is often not offered to these patients. Interventional therapies for mitral valve therapy might therefore constitute a novel therapeutic ...
Sartipy Ulrik U Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden. - - 2013
A 76-year old male on warfarin due to atrial fibrillation was admitted with Staphylococcus aureus septicaemia. Echocardiography demonstrated mitral valve endocarditis, and shortly thereafter, he suffered an intracranial haemorrhage as a result of septic embolism. Four weeks later, cardiac magnetic resonance imaging revealed a newly formed pseudoaneurysm. A left ventricular ...
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