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Berton Giuseppe - - 2010
C-reactive protein (CRP) is an established prognostic marker in the setting of acute coronary syndromes. Recently, albumin excretion rate also has been found to be associated with adverse outcomes in this clinical setting. Our aim was to compare the prognostic power of CRP and albumin excretion rate for long-term mortality ...
Fornengo C - - 2010
The aim of this study was to describe the five-year prognosis of an Italian cohort of patients following acute myocardial infarction (AMI) occurred at age ≤45 years and to investigate the potential role of risk predictors for future cardiovascular events (CVE). The study enrolled 112 consecutive patients aged ≤45 years ...
Parodi Guido - - 2010
This study sought to assess the relationship between 1-year mortality and baseline patient risk in the HORIZONS-AMI (Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction) trial. The HORIZONS-AMI trial showed that bivalirudin compared with unfractionated heparin (UFH) plus glycoprotein IIb/IIIa inhibitors (GPI) decreased major bleeding and 30-day and ...
Sedlak Tara L - - 2010
Studies before the turn of the century reported sex differences in procedure rates. It is unknown whether these differences persist. To examine time trends and sex differences in coronary catheterization and revascularization following acute myocardial infarction (AMI). A retrospective analysis was performed of all patients 20 years of age or ...
Yang Shi-Wei - - 2010
OBJECTIVE: To assess the association between fasting plasma glucose (FPG) levels on admission and mortality in older patients with acute myocardial infarction (AMI), and compare the effects of FPG levels on outcomes in the context of contemporary treatments, including drug treatment, percutaneous coronary intervention and coronary artery bypass grafting. METHODS: ...
Mehri Sounira - - 2011
The objective of the study was to explore the role of a genetic variant of angiotensinogen (AGT), M235T, as an independent risk factor for acute myocardial infarction (AMI) and to investigate the possible association with the severity of coronary artery disease (CAD), estimated on the basis of the number of ...
Agarwal Udit - - 2010
Stromal cell-derived factor (SDF)-1/CXCR4 axis has an instrumental role during cardiac development and has been shown to be a potential therapeutic target for optimizing ventricular remodeling after acute myocardial infarction (AMI) and in ischemic cardiomyopathy. Although a therapeutic target, the specific role of cardiac myocyte CXCR4 (CM-CXCR4) expression following cardiogenesis ...
Lin Xiang-Min - - 2010
Postconditioning has been shown to reduce infarct size, ischemic/reperfusion injury and myocardial injury in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). This study tested the hypothesis that postconditioning attenuates the elevation of tumor necrosis factor-alpha (TNF-alpha) and improves heart function in patients with AMI after PCI. ...
Honda Tsuyoshi - - 2010
Increased resting heart rate (HR) due to sympathetic hyperactivity is associated with coronary risk factors and increased cardiovascular events. Acute myocardial infarction (AMI) is accompanied by autonomic imbalance, which is characterized by sympathetic activation and parasympathetic inactivation. Although an increased HR in patients with acute coronary syndrome has been reported ...
Liew Reginald - - 2010
Many patients who survive an acute myocardial infarction (AMI) remain at risk of sudden cardiac death despite optimal medical treatment. AMI survivors are currently risk assessed and selected for implantable cardioverter defibrillator (ICD) insertion mainly on the basis of their left ventricular ejection fraction. Several other cardiovascular tests are available ...
Goto Kosuke - - 2010
In patients with acute myocardial infarction (AMI), both myocardial blush grade (MBG) and coronary flow pattern obtained by transthoracic Doppler echocardiography (TTDE) have limitations in assessing myocardial viability. Accordingly, we assessed the usefulness of combination of MBG and TTDE in predicting myocardial damage following AMI. A total of 45 patients ...
Abuzeid Wael - - 2011
A case of acute myocardial infarction (AMI) in a patient with anorexia nervosa is presented. Clinlcal records, electrocardiogram, echocardiogram and coronary angiogram data of a patient with anorexia nervosa, presenting with AMI were evaluated. A Pubmed literature search was used to review cardiac complications of anorexia nervosa. The patient presented ...
Ibfelt Else - - 2010
To study welding fume particles in relation to cardiovascular diseases. In 1986, 10,059 male metal workers in 75 welding companies were sent a questionnaire about their welding experience and lifestyle (83.3% response rate). Of these, 5866 were available for analysis and had ever welded at baseline. Information on exposure to ...
Maruhashi Tatsuya - - 2010
Prodromal angina pectoris (AP) has a cardioprotective effect by the mechanism of ischemic preconditioning, and the QRS score on the admission electrocardiogram (ECG) reflects myocardial damage at presentation. This study was undertaken to investigate the effect of prodromal AP on infarct progression after the onset of acute myocardial infarction (AMI). ...
Candido Elisa - - 2011
To examine the relationship between selective nonresponse to a psychosocial questionnaire and mortality after acute myocardial infarction (AMI). Two thousand six hundred and ninety AMI survivors after AMI hospitalization were recruited to complete a 30-day follow-up interview. Patients were classified into four groups (survey nonparticipation and complete, partial, and no ...
Semb A G - - 2010
OBJECTIVES: To examine the rates of acute myocardial infarction (AMI) and ischaemic stroke (IS) and to examine the predictive value of total cholesterol (TC) and triglycerides (TG) for AMI and IS in patients with rheumatoid arthritis (RA) and people without RA. METHODS: In the Apolipoprotein MOrtality RISk (AMORIS) Study 480 ...
Sim Doo Sun - - 2010
The Korea Acute Myocardial Infarction Registry (KAMIR) was the first nationwide, population-based, multicenter data collection registry in Korea designed to track outcomes of patients presenting with acute myocardial infarction (AMI). The registry included 51 community and teaching hospitals and contained data on 14,870 patients through January 2008. Patients with non-ST-elevation ...
Twerenbold Raphael - - 2010
Acute myocardial infarction (AMI) is the major cause of death worldwide. Cardiac troponins (cTns) are structural proteins, unique to the heart, that currently form the cornerstone of the AMI diagnosis. The major limitation of standard cTn assays is a sensitivity deficit at presentation caused by a delayed increase of circulating ...
Bian Yuan - - 2010
Aldehyde dehydrogenase-2 (ALDH2) is a key enzyme of alcohol metabolism, catalyzing the conversion of aldehyde to acetic acid. The G-to-A polymorphism in exon 12 of the ALDH2 gene, which causes Glu-to-Lys substitution at codon 504, has been shown to be an independent risk factor for acute myocardial infarction (AMI). We ...
Marra Martina Perazzolo - - 2010
BACKGROUND: Although angiographic perfusion has been traditionally evaluated by myocardial blush grade (MBG), pathophysiologic features underlying different MBG and the persistent blush, traditionally called staining, have been poorly explained. The aim of the study was to evaluate the correlation between MBG and morphologic aspects on cardiac magnetic resonance (CMR). METHODS: ...
Ozawa Takuya - - 2010
Erythropoietin (EPO) has been found to have anti-apoptotic and tissue protective effects on the myocardium. The aim of the present pilot study was to observe the safety and efficacy of EPO administration for patients with acute myocardial infarction (AMI). Patients admitted with AMI had all undergone successful percutaneous coronary intervention ...
Steinvil Arie - - 2010
Previous studies have demonstrated the presence of increased erythrocyte aggregation (EA) in patients with acute coronary syndromes (ACS). We have presently explored the correlation between the time from symptom onset to the appearance of an inflammatory response and aggregated erythrocytes in the peripheral blood of ACS patients. Consecutive individuals undergoing ...
Nozawa Naoki - - 2010
Monocytes and macrophages have been shown to play major roles in the progression of atherosclerosis. This study examined whether the circulating monocyte count can be used to predict coronary plaque progression of non-culprit intermediate lesions in acute myocardial infarction (AMI). Intravascular ultrasound findings of non-culprit intermediate plaque in 90 patients ...
Heitner John F - - 2010
Inflammation has been shown to be a major component in the pathophysiology of acute coronary syndrome (ACS). In patients presenting with acute myocardial infarction (AMI), a critical component of the ACS spectrum, multiple coronary arteries are involved during this inflammatory process. In addition to the coronary vasculature, the inflammatory cascade ...
Rocha Antônio Sérgio Cordeiro da - - 2010
The monitoring of healthcare quality indicators (HCQI) is a process of utmost importance in patient healthcare services. To evaluate whether the monitoring of HCQI and the root-cause analysis improve the healthcare quality in acute myocardial infarction (AMI). A cross-sectional and comparative analysis of HCQI was performed in patients with AMI ...
Chen Jiann-Hwa - - 2010
OBJECTIVE: The aims of this study are to analyze the factors that predispose the occurrence of ventricular arrhythmia (VA) in young patients with a first acute myocardial infarction (AMI) in the emergency department (ED) and to establish predictive implications. METHODS: This is a 10-year retrospective cohort study. Patients who were ...
Prech Marek - - 2010
Apoptosis is recognized as a mechanism of cell loss in the setting of acute myocardial infarction (AMI). Whether it contributes to myocyte elimination late after AMI has not yet been confirmed. We attempted to identify the features of apoptosis in myocytes that survived AMI. A search for ongoing apoptosis was ...
Cheng Yunhui - - 2010
miRNAs (microRNAs) participate in many diseases including cardiovascular disease. In contrast with our original hypothesis, miRNAs exist in circulating blood and are relatively stable due to binding with other materials. The aim of the present translational study is to establish a method of determining the absolute amount of an miRNA ...
Erden Ismail - - 2010
Data related to the incidence and clinical outcome of acute myocardial infarction (AMI) in patients with preexisting coronary artery ectasia (CAE) are limited. We assessed whether infarct-related artery ectasia (EIRA) indicates an untoward clinical outcome in patients with AMI undergoing primary percutaneous coronary intervention (pPCI). Consecutive patients (n = 643) ...
Xia Shuang - - 2010
AIMS: To investigate dynamic changes in the expression of HCN2, HCN4, as well as KCNE1, and KCNE2 mRNA and protein levels in ventricular cells from acute myocardial infarction (AMI) rat hearts. MAIN METHODS: An AMI model was induced by ligating the left anterior descending coronary artery (LAD) of Sprague-Dawley rats. ...
Begieneman Mark P V - - 2010
In the present study, ultrastructural analysis of mitochondrial deposits (black dots within mitochondria) as a method for the detection of early acute myocardial infarction (AMI) was evaluated. In 24 patients with AMI and six controls, analysis was performed in the heart of infarcted patients and noninfarcted controls. In the infarction ...
Fesmire Francis M - - 2010
OBJECTIVE: No information is currently available regarding the optimal cutoff values of the baseline ST-segment deviation sum (STDsum(baseline)) and 60-minute ST-segment deviation change (STDchange(60 min)) for predicting acute myocardial infarction (AMI). METHODS: A retrospective study was performed in 783 admitted patients with chest pain who had suspected acute coronary syndrome ...
Abbate Antonio - - 2010
Acute myocardial infarction (AMI) initiates an intense inflammatory response in which interleukin-1 (IL-1) plays a central role. The IL-1 receptor antagonist is a naturally occurring antagonist, and anakinra is the recombinant form used to treat inflammatory diseases. The aim of the present pilot study was to test the safety and ...
Van Belle Eric - - 2010
BACKGROUND: Little is known about the capacity of ischemia-modified albumin (IMA) plasma concentration to predict long-term cardiac outcome in patients with established acute myocardial infarction (AMI). Because IMA is a marker of ischemia rather than myocardial cell damage, we hypothesized that IMA plasma levels could provide additional prognostic value to ...
Schopfer David - - 2010
The American College of Cardiology/American Heart Association guidelines for acute myocardial infarction related to process of care aim to decrease morbidity and mortality and provide a standard of care for patients with acute myocardial infarction (AMI). Currently, there are limited data comparing adherence between centers providing fibrinolytic therapy alone and ...
Wi Jin - - 2010
Coronary artery aneurysms are uncommon, are usually associated with atherosclerosis, and rarely involve all three major coronary arteries. The present report describes a rare case of a young female patient presenting with acute myocardial infarction (AMI). Coronary angiography revealed multiple severe aneurysmal and stenotic changes. Based on clinical feature and ...
Arruda-Olson Adelaide M - - 2010
To examine left ventricular (LV) function in patients after acute myocardial infarction (AMI) and assess its relation to C-reactive protein (CRP) as a measure of the early inflammatory response. We measured the CRP levels early after AMI and correlated them with the early structural and functional cardiac alterations. From November ...
Park Hyo Eun - - 2010
The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 ...
Weir Robin A P RA Cardiology Department, Western Infirmary, Glasgow, Scotland, UK. - - 2010
Monocyte chemoattractant protein-1 (MCP-1) is elevated after acute myocardial infarction (AMI), and potentiates left ventricular (LV) remodeling in murine models of AMI. We examined the relationships between serum MCP-1, change in LV function and biomarkers related to remodeling in a cohort of AMI patients. Serum MCP-1 concentrations were measured in ...
Milonas Christos - - 2010
Controversy exists regarding whether all patients with acute myocardial infarction (AMI) benefit from angiotensin-converting enzyme inhibitors (ACEIs). We examined the association between ACEI treatment and mortality in a large, unselected population of patients with AMI. The present study included 105,224 patients with AMI who were not treated with ACEIs on ...
Sartorius Jennifer A - - 2010
Background/Aims: Study populations are commonly identified using a single data source. However, the inclusion criteria may result in an unacceptable level of false positives/negatives. The utilization of multiple sources may allow for more complex inclusion criteria, therefore improving the accuracy of identification of cases and controls for use in research. ...
Bolognese Leonardo - - 2010
BACKGROUND: Contrast-induced acute kidney injury (CI-AKI) is a complex syndrome of acute renal failure occurring after the administration of contrast media and contributing to prolonged hospital stay and mortality. The risk of CI-AKI is higher among patients undergoing primary percutaneous coronary interventions for acute myocardial infarction (AMI), but its clinical ...
You L - - 2010
Serum levels of pregnancy-associated plasma protein-A (PAPP-A), high-sensitivity C-reactive protein (hs-CRP) and tumour necrosis factor-alpha (TNF-alpha) were measured in 70 patients with acute coronary syndrome (ACS), comprising 18 with unstable angina (UA), 37 with acute myocardial infarction (AMI) and 15 with stable angina (SA); 15 healthy controls were also included. ...
Archbold R Andrew - - 2010
Thrombolytic therapy reduces mortality in patients with acute myocardial infarction (AMI) and left bundle branch block (LBBB). The difficulty in accurately diagnosing AMI in patients with LBBB, however, might result in their undertreatment. Among 3,890 patients hospitalized with chest pain, 241 (6.2%) had LBBB at presentation. The only variable independently ...
Olea Fernanda D - - 2010
The effects of growth hormone (GH) on infarct size and left ventricular (LV) function in experimental acute myocardial infarction (AMI) have been controversial. Moreover, little, if any, information exists regarding long-term evaluation of therapeutic doses of GH in large mammalian models of AMI. We therefore aimed to assess the effect ...
Paparella Domenico - - 2010
BACKGROUND: The optimal timing for coronary artery bypass grafting (CABG) in patients with recent acute myocardial infarction (AMI) is unclear. Cardiac troponin I (cTnI) is a widely accepted biomarker of myocardial damage. The objective of this study was to determine whether preoperative cTnI values could be used to determine risk ...
Evanchan Jason - - 2010
The purpose of this study was to determine the readmission rate for acute myocardial infarction (AMI) in patients discharged on clopidogrel and a proton-pump inhibitor (PPI) versus patients discharged on clopidogrel alone after experiencing an AMI and undergoing stent placement. Clopidogrel is a prodrug that requires metabolism in the liver ...
Katashima Takashi - - 2010
S100A8/A9 complex (S100A8/A9) is expressed in activated human neutrophils and macrophages. Enhanced expression of S100A8/A9 in atherosclerotic plaque of patients with unstable angina pectoris (UAP) has been demonstrated, but its profile in acute myocardial infarction (AMI) has not been clarified. Serum S100A8/A9 levels were serially measured in patients with AMI ...
Huang Shao-Sung - - 2010
AIM: There is uncertainty about the association between circulating concentrations of adiponectin and coronary heart disease risk, particularly in patients after acute myocardial infarction (AMI). The goal of this study was to determine whether plasma adiponectin levels could predict future cardiovascular events in patients after AMI, and to elucidate the ...
Biswas Santanu - - 2010
Acute myocardial infarction (AMI) is a leading cause of death. Inflammatory processes play an important role in atherosclerosis, which is intimately related to AMI. The aim of this study was to investigate the association between anti-inflammatory and pro-inflammatory cytokines ratios and AMI. A total of 90 AMI patients and 90 ...
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