Search Results
Results 351 - 400 of 2500
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Shimada Yoshihisa - - 2012
A large thrombus load on the culprit coronary artery of patients with acute myocardial infarction (MI) is associated with increased procedural complications and adverse coronary events following angioplasty. This case series describes effective removal of large, occlusive thrombi in acute MI via direct aspiration using a standard 6 Fr guide ...
Bajaj Ravi R - - 2012
The early diagnosis of acute coronary syndrome (ACS) remains challenging, and a considerable proportion of patients are diagnosed with "possible" ACS on admission. The Global Registry of Acute Coronary Events (GRACE/GRACE(2)) and Canadian Registry of Acute Coronary Events (CANRACE) enrolled 16,618 Canadian patients with suspected ACS in 1999 to 2008. ...
Pinelli Arnaldo - - 2012
Coronary artery diseases (CAD) evolving into acute myocardial infarction (AMI) is associated with coagulation and thrombotic occlusion of coronary vessels in the presence of unstable atheroma. The atheromatous plaque becomes unstable when it is infiltrated by monocytes, macrophages and neutrophils capable of secreting proteases that induce plaque erosion, rupture and ...
Palmerini Tullio - - 2012
This study sought to develop a new score specific for patients with non-ST-segment elevation acute coronary syndromes (NSTEACS) undergoing percutaneous coronary intervention (PCI) (the ACUITY-PCI [Acute Catheterization and Urgent Intervention Triage Strategy-Percutaneous Coronary Intervention] risk score). The TIMI (Thrombolysis In Myocardial Infarction) and GRACE (Global Registry for Acute Coronary Events) ...
Dangas George D - - 2012
This study sought to develop a practical risk score to predict the risk of stent thrombosis (ST) after percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS). ST is a rare, yet feared complication after PCI with stent implantation. A risk score for ST after PCI in ACS can be ...
Gorenek Bulent - - 2012
Atrial fibrillation (AF) is a common arrhythmia in the setting of acute coronary syndrome and acute ST-elevation myocardial infarction (STEMI). This review summarizes recent evidence on the clinical and prognostic significance of pre-existent and new-onset AF in acute STEMI patients and highlights new emerging predictors of AF development in the ...
McManus David D DD Department of Medicine, University of Massachusetts Medical School, Worcester; Division of Epidemiology, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, - - 2012
Atrial fibrillation is common among patients with cardiovascular disease and is a frequent complication of the acute coronary syndrome. Data are needed on recent trends in the magnitude, clinical features, treatment, and prognostic impact of preexisting and new-onset atrial fibrillation in patients hospitalized with an acute coronary syndrome. The study ...
English Michael L - - 2012
ABSTRACT: Left ventricular assist device (LVAD) placement is becoming more common as a treatment of end-stage heart failure. People who have undergone placement of an LVAD typically have deficits with their activities of daily living as well as decreased strength from prolonged immobility. Patients often benefit from admission to acute ...
Shah Neomi - - 2012
BACKGROUND: Obstructive sleep apnea (OSA) is characterized by intermittent hypoxia (IH). In animal models, IH has been shown to protect the myocardium during periods of ischemia by reducing infarct size. However, this phenomenon of "ischemic preconditioning" has not been investigated among OSA patients with acute myocardial infarction (MI). This study ...
Kong Chee Hoe CH Department of Cardiac, Thoracic and Vascular Surgery, National University Heart Centre, - - 2013
Extracellular matrix (ECM) remodelling of the vessel wall is hypothesized to be an important step in atherosclerosis. Changes of the ECM are associated with the gradual progression of an atherosclerotic lesion from a lipid streak to complicated unstable plaque, leading to a complete vessel occlusion and eventually myocardial infarction (MI). ...
Navarro Víctor René - - 2012
Between 1994 and 2009, the Dr Gustavo Aldereguía University Hospital of Cienfuegos, Cuba implemented a series of interventions that reduced acute myocardial infarction case fatality rate from 47% to 15%. These interventions were part of an institutional plan for myocardial infarction included in the hospital's overall quality assurance strategy. Outcomes ...
Ramasubbu Kumudha - - 2012
Long-term heart failure (HF) treatment has been shown to result in reverse chamber remodeling. However, it is unknown whether sizes of cardiac chambers acutely change during HF therapy and whether these changes are associated with favorable clinical outcomes. Using the Evaluation Study of Congestive Heart Failure and Pulsmonary Artery Catheterization ...
Mistry Neville F - - 2012
Acute coronary syndromes result in a significant burden of morbidity and mortality in the United States. This spectrum of acute coronary thrombosis (including unstable angina, non-ST-segment elevation myocardial infarction, and ST-elevation myocardial infarction) has been well studied in large clinical trials. This review details the initial management of patients presenting ...
Tatlı Ersan - - 2012
Sildenafil was the first oral compound to be approved for the treatment of erectile dysfunction. It is a selective inhibitor of isoform 5 of phosphodiesterase, which is the enzyme responsible for the breakdown of 3', 5'-cyclic guanosine mono-phosphate. Sildenafil-associated myocardial infarction (MI) is rarely seen in patients without previous history ...
Javadi H - - 2012
99mTc-sestamibi has been investigated as a potential viability marker; initial studies have shown good concordance between 201Tl and 99mTc-sestamibi activities in both viable and nonviable myocardium. However, assessment of myocardial viability by 99mTc-sestamibi remains controversial for tissue recovery after revascularization. Here, we present a patient with several regions of severely ...
Oh In Soo - - 2012
We experienced a case of acute myocarditis as the initial presentation of Crohn's disease. A 19-year-old woman was admitted with impaired consciousness, shock, and respiratory failure. She had suffered from frequent diarrhea and abdominal pain for several years. Cardiac troponin I and creatine kinase-MB fraction levels were elevated to 5.32 ...
Jansson Anna M - - 2012
OBJECTIVE: CXCL16 and osteoprotegerin (OPG) both predict mortality in acute coronary syndromes. We hypothesized that a combination of CXCL16 and OPG concentrations would add prognostic information to the Global Registry of Acute Coronary Events (GRACE) score in patients hospitalized for acute coronary syndromes. METHODS AND RESULTS: We assessed the associations ...
Vermes Emmanuelle - - 2012
PURPOSE: To assess the Otsu-Auto-Threshold (OAT) for accuracy and reproducibility for sizing irreversible injury in late gadolinium enhancement (LGE) images of patients with acute heart disease. The OAT method automatically identifies high signal intensity areas using a cutoff derived from the signal intensity histogram and therefore is user-independent. MATERIALS AND ...
Fermann Gregory J GJ Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 34267-0769, USA. - - 2012
Galectin 3 (G3) is a mediator of fibrosis and remodeling in heart failure. Patients diagnosed with and treated for Acute Heart Failure Syndromes were prospectively enrolled in the Decision Making in Acute Decompensated Heart Failure multicenter trial. Patients with a higher G3 had a history of renal disease, a lower ...
Schau Thomas - - 2012
AIMS: Identifying potential responders to cardiac resynchronization therapy (CRT) may be sometimes difficult and time consuming. Searching for a simple method, we chose vectorcardiography (VCG) for our study. The aim was to evaluate whether a VCG parameter can be used to predict invasively measured acute hemodynamic changes after CRT onset. ...
Meimoun Patrick - - 2012
AIMS: Typical tako-tsubo cardiomyopathy (TTC) mimics acute anterior myocardial infarction (AMI) and the differential diagnosis is challenging before coronary angiography (CA) is performed; it demonstrates reduced or absent antegrade flow in the left anterior descending artery (LAD) in AMI, whereas there is no such flow limiting in TTC. At the ...
Liao Ying-Chieh - - 2012
Eosinophilic myocarditis is recognized by severe heart failure and marked eosinophilia infiltration resulting from different etiologies. Acute necrotizing eosinophilic myocarditis, the initial presentation of the disease, is rare and often fatal, with unique echocardiographic pictures, and followed by endocardial thrombosis and chronic endomyocardial fibrosis. We report a young female with ...
Imanishi Junichi - - 2012
Although left ventricular (LV) mechanical dyssynchrony can predict the response to cardiac resynchronization therapy (CRT), the presence of baseline LV dyssynchrony might not be the only determinant of the response to CRT. The objectives of the present study were to test the hypothesis that a combined assessment of baseline LV ...
Simon Tabassome T Department of Clinical Pharmacology, URC-EST, Assistance Publique-Hôpitaux de Paris (APHP), Hôpital St Antoine Paris, University of Pierre et Marie Curie, 27 Rue Chaligny, 75012 Paris, France. - - 2013
Interleukin (IL)-17 pathway is being clinically targeted in immune-mediated diseases, most of which are associated with a significant cardiovascular risk. We investigated the relationship between serum levels of IL-17 and the risk of cardiovascular events in patients with acute myocardial infarction. We used data from 981 patients enrolled in the ...
Laskarin G - - 2012
Heat shock proteins (HSPs) have changed very little with evolution, suggesting that they play important role(s) in cellular survival. Specifically, HSPs protect cells from induced cell death. Their expression is triggered by heat or other stress, such as ischemia. HSPs provide protection against protein denaturation, although they slightly differ with ...
Birnbaum Yochai - - 2012
Acute coronary syndromes (ACS) with narrow QRS are divided into 2 groups: ST-elevation ACS that requires emergency percutaneous coronary intervention, and non-ST elevation ACS. The classification of ACS into these 2 groups is not always straightforward. In this document, we discuss several electrocardiogram patterns of acute ischemia that are often ...
Ali W M - - 2012
Using data from the 2nd Gulf Registry of Acute Coronary Events (Gulf RACE-2) in 2008-09 we investigated the in-hospital complications and 1-year outcome of acute coronary syndrome (ACS) in patients with systemic hypertension from 6 Gulf countries. Of 7847 consecutive patients admitted with ACS, 3746 (47.7%) had hypertension. Hypertension was ...
Yurtdaş Mustafa - - 2012
Marijuana is known to have been used for medicinal and recreational purposes for thousands of years. Although marijuana has some diverse effects on cardiovascular system, there is insufficient knowledge concerning acute myocardial infarction (AMI) associated with marijuana and its underlying mechanism. We report the case of a 26 year-old young ...
Takahashi Teruyuki - - 2012
Thalamic lesions give rise to a variety of clinical syndromes such as pure sensory stroke, ataxic hemiparesis, and rarely involuntary movements including chorea. Generally and classically, lacunar infarction in the subthalamic nucleus has been regarded as the lesion mainly responsible for hemi-chorea and hemi-ballismus, on the basis of previous anatomical ...
Correia Luis C L - - 2012
We aimed to test the hypothesis that clinically suspected obstructive sleep apnea (OSA) independently predicts worse in-hospital outcome in patients with non-ST elevation acute coronary syndromes. At admission, individuals were evaluated for clinical probability of OSA by the Berlin Questionnaire. Primary cardiovascular endpoint was defined as the composite of death, ...
Gil Gislaine Pinn GP Hospital Zona Sul de Londrina, PR, - - 2012
to assess the clinical evolution of patients hospitalized due to the first episode of Acute Coronary Syndrome (ACS) according to its clinical manifestation. data were collected from 234 patients, hospitalized between May 2006 and July 2009 due to the first episode of an ACS, by consulting their medical records. 234 ...
Turunen K E A - - 2012
BACKGROUND AND PURPOSE: Cerebral cortical infarctions are often considered to be associated with more severe cognitive deficits than subcortical infarctions, but the evidence is conflicting. We compared early and late cognitive deficits between cortical and subcortical lesions. METHODS: Consecutive patients with first-ever cortical (n = 61) or subcortical (n = 71) cerebral infarctions were ...
Knecht Sven - - 2012
Anatomical Predictors for Acute and Mid-Term Success of Cryoballoon Ablation. Introduction: Cryoballoon (CB) pulmonary vein isolation (CB-PVI) for the treatment of paroxysmal atrial fibrillation (AF) has been demonstrated to be safe and reliable. Preprocedural patient selection to address the high variability in pulmonary vein (PV) anatomy may improve the acute and ...
Overton John - - 2012
BACKGROUND: Acute myeloid leukemia (AML) is usually associated with coagulopathy and disorders of hemostasis, but cases of ischemic events have been reported. We present a case of AML with recurrent acute limb ischemia and multiple organ infarctions. METHODS AND RESULTS: A 57-year-old woman diagnosed with AML subtype M1 developed recurrent ...
Hudzik Bartosz - - 2012
Situs inversus with dextrocardia is a rare condition. Yet, the incidence of atheroclerosis and myocardial infarction in patients with dextrocardia is similar to that in general population. The diagnosis of acute myocardial infarction is somewhat tricky and difficult if the dextrocardia is not recognized. We present the electrocardiogram, coronary angiograms, ...
Foell D - - 2012
OBJECTIVES: The aim of this study was the evaluation of left ventricular (LV) segmental 3D velocities in patients with hypertensive heart disease using magnetic resonance (MR) tissue phase mapping (TPM). METHODS: LV radial, long-axis and rotational myocardial velocities were assessed by TPM in patients with LV hypertrophy and preserved EF ...
Chantadansuwan Thamarath - - 2012
Primary percutaneous coronary intervention (PCI) in acute ST elevation myocardial infarction (STEMI) is a clinical challenge. Adequate thrombus removal before stenting is an important factor that predicts procedural success, and finally reflects to clinical outcomes. In the present report, 2 cases of acute STEMI underwent primary PCI. Coronary angiogram (CAG) ...
Bennett Johan - - 2012
A 65-year-old man developed respiratory failure and was admitted to the Intensive Care Unit for positive pressure ventilation and antibiotic and antifungal therapy.There was a sudden deterioration with chest pain, worsening hypoxia and hypotension. Serial electrocardiograms showed new onset right bundle-branch block with developing anterior ST-segment elevation. An urgent coronary ...
De Vuyst Elke - - 2012
We present a case of acute anterior myocardial infarction in a breastfeeding woman, 10 days after delivery. The presumed cause was proximal left anterior artery vasospasm, induced by a combination of smoking a first cigarette in the early morning and salbutamol inhalation, in the particular context of peripartum. We discuss ...
Shimoni Sara - - 2012
Evaluation of: Damani S, Bacconi A, Libiger O et al. Characterization of circulating endothelial cells in acute myocardial infarction. Sci. Transl. Med. 4(126), 126ra33 (2012). Acute coronary syndromes are the most common cause of death in the Western world. Plaque rupture is most commonly associated with acute coronary events, although ...
Srikanth Sundararajan - - 2012
Atherosclerosis is a systemic vascular pathology that is preceded by endothelial dysfunction. Vascular inflammation "fuels" atherosclerosis and creates the milieu for episodes of intravascular thromboses. Thrombotic events in the coronary vasculature may lead to asymptomatic progression of atherosclerosis or could manifest as acute coronary syndromes or even sudden cardiac death. ...
Showkathali Refai - - 2012
Antiplatelet and antithrombotic agents significantly alter the clinical course of patients with acute coronary syndrome (ACS) and hence form the bedrock of the management pathway of this closely related continuum of coronary pathologies. The contemporary therapeutic armamentarium for the treatment of ACS now reflects the many technical and pharmacological advances ...
Witkowski Tomasz G - - 2012
AIMS: Despite a successful surgical procedure and adherence to current recommendations, postoperative left ventricular (LV) dysfunction after mitral valve repair (MVr) for organic mitral regurgitation (MR) may still occur. New approaches are therefore needed to detect subclinical preoperative LV dysfunction. LV global longitudinal strain (GLS), assessed with speckle-tracking echocardiographic analysis, ...
Martin David O - - 2012
In patients with sinus rhythm and normal atrioventricular conduction, pacing only the left ventricle with appropriate atrioventricular delays can result in superior left ventricular and right ventricular function compared with standard biventricular (BiV) pacing. To evaluate a novel adaptive cardiac resynchronization therapy ((aCRT) algorithm for CRT pacing that provides automatic ...
Tsikrikas Spyros - - 2012
The implantable cardioverter-defibrillator (ICD) has been proven to reduce the mortality of patients with life-threatening ventricular arrhythmias, and has become the therapy of choice for patients with aborted sudden cardiac death or poorly tolerated ventricular tachycardias. Abrupt changes in ventricular cycle lengths or short-long-short (S-L-S) sequences might precede the initiation ...
Rao H-B - - 2012
Cerebral infarction will cause ischemic encephalopathy and lactate accumulation in the brain in acute cerebral infarction. This study investigated the optimization of pulse sequences for lactate detection and its diagnostic value in acute cerebral infarction using proton MR spectroscopy ((1)H MRS). The studies were performed on a phantom and on ...
Catena Emanuele - - 2012
Ventricular assist devices are electromechanical pumps used for circulatory support of patients with severe heart failure. Current ventricular assist device therapy provides a broad spectrum of support systems ranging from short-term to long-term devices. Echocardiography is an ideal modality to monitor patients undergoing mechanical circulatory support because it is less ...
Sun Q N - - 2012
We investigated the regeneration of cardiac lymphatic vessels and capillaries in the infarcted myocardiac zones after acute myocardial infarction in rats. The anterior descending artery of the heart was ligated for infarction and both immunohistochemistry and immunofluorescence were used to detect pathological changes of lymphatic vessels in infarcted zone (IZ), ...
Daly Mj - - 2012
This study sought to determine whether 80-lead body surface potential mapping (BSPM) would improve detection of acute myocardial infarction (AMI) and occluded culprit artery in patients presenting with ST-segment depression (STD) only on 12-lead ECG. In patients with acute coronary syndromes (ACS), the standard 12-lead ECG has limited sensitivity (50-60%) ...
Turco Mark A - - 2012
Background: With the changing health care environment, cost effectiveness is an important adjunct to clinical investigation when assessing new medical devices. This study presents an economic model to evaluate cost effectiveness of coronary stents. Methods: Markov modeling was developed comparing total costs (Medicare payer perspective) between TAXUS Liberté and TAXUS ...
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