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Vallakati Ajay - - 2013
After coronary artery bypass graft (CABG) surgery, patients can present with challenging lesions in the setting of acute coronary syndrome, particularly with high clot burden. Techniques including thrombectomy and local delivery of glycoprotein IIb/IIIa inhibitors have been utilized for these saphenous venous graft lesions. We report a case involving a ...
Kumar Anupam - - 2013
Takotsubo cardiomyopathy (TC), also known as broken-heart syndrome, is usually the result of a stressful event. It is more common in postmenopausal females and can mimic an acute coronary syndrome. We report the case of an elderly female who presented with acute chest pain and ECG changes suggestive of an ...
Reynolds Matthew R MR Departments of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri, - - 2013
Gamma Knife radiosurgery (GKS) is a primary treatment modality for small, surgically-challenging meningiomas of the skull base in carefully selected patients. Despite the overall low incidence of complications from this procedure, rare instances of hemorrhagic events following GKS have been reported. In fact, only a single, probable case of acute ...
Sim Doo Sun - - 2013
The benefit of early statin treatment following acute myocardial infarction (MI) complicated with cardiogenic shock (CS) has not been well studied. We sought to assess the effect of early statin therapy in patients with CS complicating acute MI. We studied 553 statin-naive patients with acute MI and CS (Killip class ...
Milberg Peter - - 2013
AIMS: In several clinical and pre-clinical studies, application of ranolazine (RAN) led to suppression of atrial fibrillation (AF). The aim of the present study was to investigate whether RAN can suppress AF in an experimental rabbit whole heart model, in which acute haemodynamic changes trigger AF. Ranolazine was compared with ...
Yang Kun-Pin - - 2013
Acute pericarditis is a rare complication of percutaneous coronary intervention (PCI). Here, we describe a case of PCI complicated by guidewire perforation and contrast extravasation. Acute pericarditis developed 36 hours after PCI procedure with fever and severe chest pain. Electrocardiogram showed ST elevation in inferior-lateral leads. However, the follow-up coronary ...
Ezekowitz Justin A - - 2013
Acute heart failure is a public health issue with morbidity and mortality exceeding that of myocardial infarction. Novel compounds for the treatment of acute heart failure are clearly needed and fall into the general categories of inotropic, vasodilatory and other compounds in phase I to III of development. Furthest along ...
Paulin Vera Carmen Maria - - 2013
Cocaine has become one of the most commonly abused recreational drugs, resulting in a significantly increased number of visits to the emergency department due to the acute symptoms caused by its intake. The acute onset of cardiovascular complications, such as myocardial infarction, arrhythmias, stroke, and kidney and spleen infarction, has ...
Lee Ki Hong - - 2013
As the first nationwide Korean prospective multicenter data collection registry, the Korea Acute Myocardial Infarction Registry (KAMIR) launched in November 2005. Through a number of innovative approaches, KAMIR suggested new horizons about acute myocardial infarction (AMI) which contains unique features of Asian patients from baseline characteristics to treatment strategy. Obesity ...
De Rosa Salvatore - - 2013
BACKGROUND: CELL-BASED THERAPIES ARE A PROMISING OPTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION OR CHRONIC HEART FAILURE (CHF). HOWEVER, ADMINISTRATION OF CELLS REQUIRES INTRACORONARY OR INTRACARDIAC INSTRUMENTATION, WHICH IS POTENTIALLY ASSOCIATED WITH PERIPROCEDURAL RISKS. THEREFORE, WE ANALYZED PERIPROCEDURAL COMPLICATIONS AND 30-DAY OUTCOME IN 775 CONSECUTIVE PROCEDURES OF INTRACORONARY ADMINISTRATION OF ...
Kukwa Wojciech - - 2013
BACKGROUND: A high level of endogenous erythropoietin (EPO) may be associated with a smaller infarct size determined by the release of necrosis markers. Sleep-disordered breathing (SDB) is a well-known risk factor for cardiovascular diseases. In contrast, protective effects of SDB have also been described. The potential role of increased levels ...
Nymark Carolin - - 2013
Background:In acute myocardial infarction the risk of death and loss of myocardial tissue is at its highest during the first few hours. However, the process from symptom onset to the decision to seek medical care can take time. To comprehend patients' pre-hospital delay, attention must be focused on the circumstances ...
Sørensen Jacob Thorsted JT Department of Cardiology, Aarhus University Hospital, Aarhus, - - 2013
Technological advances over the past decades have allowed improved diagnosis and monitoring of patients with acute coronary syndromes as well as patients with advanced heart failure. High-quality digital recordings transmitted wirelessly by cellular telephone networks have augmented the prehospital use of transportable electrocardiogram machines as well as implantable devices for ...
Teixeira Rogério - - 2013
For the time being, acute myocardial infarction represents a history of success concerning diagnose, management and treatment, whereas it was considered a fatal disease in the beginning of the 1900s. The present paper is aimed at reviewing the landmarks of acute myocardial infarction, as key historical concepts are an important ...
Sørensen Jacob Thorsted JT Department of Cardiology, Aarhus University Hospital, Aarhus, - - 2013
Technological advances over the past decades have allowed improved diagnosis and monitoring of patients with acute coronary syndromes as well as patients with advanced heart failure. High-quality digital recordings transmitted wirelessly by cellular telephone networks have augmented the prehospital use of transportable electrocardiogram machines as well as implantable devices for ...
Sulo Gerhard - - 2013
BACKGROUND: Immune system activation is involved in atherosclerosis. Neopterin production and tryptophan catabolism through the kynurenine pathway, measured by the kynurenine-tryptophan ratio (KTR), are induced by interferon gamma, thus both are considered markers of cell mediated immune activation. This study prospectively investigated their predictive value on acute coronary events among ...
Beigel Roy - - 2013
Coronary computed tomographic angiography can detect nonobstructive atherosclerotic lesions that would not otherwise have been detected with functional cardiac imaging. Currently, limited data exist regarding the clinical significance of these lesions in patients with acute chest pain. The aim of our study was to examine the prognostic significance of these ...
Jaarsma Caroline - - 2013
ABSTRACT: BACKGROUND: Although echocardiography is used as a first line imaging modality, its accuracy to detect acute and chronic myocardial infarction (MI) in relation to infarct characteristics as assessed with late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR) is not well described. METHODS: One-hundred-forty-one echocardiograms performed in 88 first acute ST-elevation ...
Wu Meng-Chen MC Department of Neurology, National Taiwan University Hospital, - - 2013
A 60-year-old man with a history of atrial fibrillation had an acute onset of ballistic movements of the left limbs with sensory extinction (video on the Neurology® Web site at www.neurology.org). The patient was treated with risperidone and anticoagulant; symptoms subsided 3 days later. Brain MRI showed acute infarction of ...
Lee Dong Gyu - - 2013
The knowledge discovery has been widely applied to mine significant knowledge from medical data. Nevertheless, previous studies have produced large numbers of imprecise patterns. To reduce the number of imprecise patterns, we need an approach that can discover interesting patterns that connote causality between antecedent and consequence in a pattern. ...
Zaliaduonyte-Peksiene Diana - - 2013
INTRODUCTION: The development of left ventricular remodelling after acute myocardial infarction is a predictor of heart failure and mortality. The purpose of the present study was to assess whether the polymorphism of angiotensinogen (AGT) gene with threonine (T) instead of methionine (M) at amino acid 235 in exon 2 (M235T) ...
Browning Alyssa Camille AC Division of Cardiovascular Medicine, University of California, Davis, Davis, California, - - 2013
A 66-year-old man with a history of coronary artery disease, stage V chronic kidney disease, peripheral arterial disease and a dual-chamber pacemaker experienced persistent chest and shoulder discomfort following his daily hemodialysis treatment. Treatment with clopidogrel had been discontinued three days previously due to impending vascular surgery. Electrocardiography revealed a ...
Vincent Anne A CNRS, UMR-5203, Institut de Génomique Fonctionnelle, 141, rue de Cardonille - 34094 Montpellier Cedex 5 - France. - - 2013
Recognition that inflammation may contribute to the pathogenesis of various cardiac diseases has naturally led to the evaluation of the therapeutic potential of a range of anti-inflammatory approaches. Unfortunately, results in most settings have been disappointing. The majority of novel approaches fail despite promising preclinical data, partly attributable to off-target ...
Sugizaki Yoichiro - - 2013
A 65-year-old man was referred to our hospital due to an acute onset of dyspnea and persistent fever. Echocardiography revealed an ejection fraction (EF) of 25% with diffuse severe left ventricular (LV) dysfunction. 18F-fluorodeoxy glucose-positron emission tomography imaging showed significantly increased uptake by the LV and right ventricular walls, indicating ...
Ertaș Faruk F Department of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, - - 2013
Acute myocardial infarction (AMI) will probably remain the most important cause of death over the next decades. Traditional risk factors of atherosclerosis could not exactly explain the development of acute coronary events such as AMI. Antiphospholipid antibody syndrome is a disorder characterized by the development of arterial and venous thrombosis. ...
Leibovitz Eyal E Department of Internal Medicine A Wolfson Medical Center, Holon, Israel. - - 2013
Chronic treatment with currently available oral hypoglyemic medications may result in a differential effect on the clinical presentation of diabetic patients with acute coronary syndrome (ACS). We evaluated presentation characteristics and the risk for in-hospital complications and 30-day major adverse cardiovascular events (MACE) among 445 patients with diabetes mellitus enrolled ...
Huang Ching-Hui - - 2013
Oxidized low-density lipoproteins (oxLDL) and oxidized low-density lipoprotein autoantibodies (OLAB) have been detected in human plasma and atherosclerotic lesions. OLAB appear to play a role in the clearance of oxLDL from circulation. Higher levels of OLAB appear to be associated with a reduced risk of a wide range of cardiovascular ...
Somasundaram K - - 2013
In this, the first of two article on medical emergencies, we discuss the definitions, epidemiology, pathophysiology, acute and chronic management of atrial fibrillation and acute myocardial necrosis in the peri-operative and intensive care settings.
Arrivi Alessio - - 2013
Slow coronary flow phenomenon (SCFP) is characterized by angiographically normal coronary arteries with delayed run-off of contrast medium across the vasculature. Its etiology and clinical significance are still not completely known; however, acute congestive heart failure (CHF) is rare in this context. A 71 year-old woman with SCFP presented with ...
Shemesh Joseph - - 2013
Coronary artery calcification (CAC) is closely related to coronary atherosclerosis. However, less is known about the clinical significance of extensive CAC (ECAC) in regard to types of first coronary events (acute vs. chronic). Diabetes mellitus (DM) represents a strong risk factor for CAD although its association with CAC is controversial. ...
Warren-Gash Charlotte C Research Department of Infection & Population Health, Centre for Infectious Disease Epidemiology, UCL, London, - - 2013
To investigate recent respiratory and influenza-like illnesses (ILIs) in acute myocardial infarction patients compared with patients hospitalised for acute non-vascular surgical conditions during the second wave of the 2009 influenza A H1N1 pandemic. Case-control study. Coronary care unit, acute cardiology and acute surgical admission wards in a major teaching hospital ...
Tokuda Michifumi - - 2013
Acute end points of catheter ablation for ventricular tachycardia (VT) remain incompletely defined. The aim of this study is to identify causes for failure in patients with structural heart disease and to assess the relation of this acute outcome to longer-term management and outcomes. From 2002 to 2010, 518 consecutive ...
Sim Doo Sun - - 2013
The clinical outcome of patients with acute myocardial infarction (MI) with unprotected left main coronary artery (LMCA) stenosis is not fully understood. We sought to assess the outcomes of patients with acute MI who underwent percutaneous coronary intervention (PCI) for unprotected LMCA stenosis. A total of 587 patients enrolled in ...
Hidalgo Sylvana S 0000-0001-6595-7928 Department of Internal Medicine, Section on Cardiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1045, - - 2013
Trastuzumab is a monoclonal antibody highly effective in the treatment of several cancers, but its use is associated with cardiac toxicity which usually responds to cessation of the drug and/or medical therapy. We present an unusual case of acute cardiac toxicity temporally related to administration of trastuzumab in which the ...
Dumrongmongcolgul Nat N Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th Street, Indiana Avenue, Lubbock, TX 79430, - - 2013
The etiology of thrombocytosis can be classified into reactive and essential forms. The rate of thromboembolic events is higher in essential thrombocytosis, and these events include strokes, transient ischemic attacks, retinal artery or retinal vein occlusions, digital ischemia, and acute coronary syndrome. In a study of 732 medical and surgical ...
Ahmed Mahmoud M Department of Internal Medicine, University of Florida, Gainesville, FL, - - 2013
Male, 47 FINAL DIAGNOSIS: Acute myocardial infarction Symptoms: Chest pain Medication: - Clinical Procedure: - Specialty: Cardiology. Unusual clinical course. Double myocardial infarction involving two culprit major vessels is a rarely reported presentation with high incidence of mortality. In this study, we report 47-year-old male patient who had an attack ...
Alexandrescu Roxana R Dr, Foster Unit at Imperial College, Department of Primary Care and Public Health, School of Public Health, Imperial College London, London EC1A 9LA, UK. - - 2013
Acute myocardial infarction (AMI) type is an important distinction to be made in both clinical and health care research context, as it determines the treatment of the patient as well as affecting outcomes. The aim of the paper was to determine the feasibility of distinguishing AMI type, either ST elevation ...
Mohindra Rohit - - 2013
Clinical questionIn emergency department patients with symptoms suggestive of acute myocardial infarction, is the absolute or relative change of cardiac troponin assays (either high sensitivity or ultrasenstive) more accurate in diagnosing acute myocardial infarction at 1 to 2 hours postpresentation?Article chosenRechlin T, Ifran A, Twerenbold R, et al. Utility of ...
Szadkowska Iwona I Department of Internal Diseases and Cardiological Rehabilitation, Medical University of Lodz, Lodz, Poland. - - 2013
Galectin-3, a biomarker associated with fibrosis and inflammation, has been implicated in development and progression of heart failure (HF) and predicts increased mortality and morbidity in this condition. HF frequently develops after myocardial infarction (MI), contributing to worse outcome. The aim of this study is to assess the association between ...
Bhatt Alok - - 2013
Cerebrovascular complications are rare following viper bites. A 65-year-old man presented with loss of consciousness and developed haemiparesis following a viper bite. Coagulation parameters were severely deranged. MRI showed acute ischaemic infarction on the left side in the precentral and postcentral gyrus, hemipons and cerebellum. Troponin T was elevated and ...
Bacci Marcelo Rodrigues - - 2013
Acute myocardial infarction (AMI) represents one of the major mortality causes in the world. Treatment of AMI is widely known; however, in developing countries some medications are not so easily available yet. We present a case of a 49-year-old black male patient who suffered an AMI and 2 weeks after ...
Bacci Marcelo Rodrigues - - 2013
We present the case of a patient who underwent an acute ST-elevation myocardial infarction of the inferior wall and transitory total heart block in the first hours of his clinical presentation. There was no haemodynamic instability before the thrombolytic therapy was performed 8 h after the onset of pain. There ...
Eppenberger Manuela - - 2013
Acute eosinophilic myocarditis is a rare cause of acute heart failure. We present the case of a 32-year-old woman who had presumptive eosinophilic myocarditis as part of a generalized hypersensitivity reaction (Drug Rash with Eosinophilia and Systemic Symptoms [DRESS] syndrome) that exhibited a dramatic response to steroid therapy. We highlight ...
Devaux Yvan - - 2013
[This corrects the article on p. e70644 in vol. 8.].
Evora Paulo Roberto B - - 2013
A modern concept considers acute coronary syndrome as an autoinflammatory disorder. From the onset to the healing stage, an endless inflammation has been presented with complex, multiple cross-talk mechanisms at the molecular, cellular, and organ levels. Inflammatory response following acute myocardial infarction has been well documented since the 1940s and ...
Sunil Roy Thottuvelil Narayanan TN Department of Cardiology, Belhoul Speciality Hospital, P.O. Box 5527, Dubai, - - 2013
Acute occlusion of the left anterior descending coronary artery (LAD) generally results in ST segment elevations in precordial leads and reciprocal ST segment depression in inferior leads. The occurrence of isolated inferior myocardial infarction due to occlusion of LAD is very rare. We describe an isolated acute inferior myocardial infarction ...
Gao Hao H University of Glasgow, Glasgow, G12 8TA, - - 2013
T2-weighted cardiovascular magnetic resonance (CMR) is clinically-useful for imaging the ischemic area-at-risk and amount of salvageable myocardium in patients with acute myocardial infarction (MI). However, to date, quantification of oedema is user-defined and potentially subjective. We describe a highly automatic framework for quantifying myocardial oedema from bright blood T2-weighted CMR ...
Esmaeilzadeh Maryam - - 2013
Echocardiography is a non-invasive diagnostic technique which provides information regarding cardiac function and hemodynamics. It is the most frequently used cardiovascular diagnostic test after electrocardiography and chest X-ray. However, in a patient with acute chest pain, Transthoracic Echocardiography is essential both for diagnosing acute coronary syndrome, zeroing on the evaluation ...
White David A - - 2013
[This corrects the article on p. e76206 in vol. 8.].
Ghosh Dastidar A - - 2013
Patients with suspected acute coronary syndrome are commonly assessed by acute physicians on arrival in hospital. Although most will recognise the typical ECG features of ST elevation myocardial infarction, the significance of ST elevation in lead aVR may not always be appreciated. This case series describes 6 cases in which ...
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