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Ito Hiroshi H Department of Cardiovascular Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Field of Functional Physiology, Okayama - - 2014
In patients with acute myocardial infarction (MI), coronary microvasculatures are often damaged irreversibly due to myocardial ischemia and reperfusion, and flow to the previously ischemic myocardium is markedly reduced, a phenomenon known as the "no-reflow phenomenon". Percutaneous coronary intervention (PCI) may accelerate embolization of plaque gruels and microthrombi to the ...
Li Qing Q The Central Laboratory of Medical Research Center, Anhui Provincial Hospital, Hefei, 230001, Anhui, People's Republic of China, - - 2014
The imbalance of CD4(+)CD25(+) regulatory T (Treg) cells and Th17 cells has shown to be involved in pathogenesis of atherosclerosis and acute coronary syndrome [ACS, including unstable angina (UA) and acute myocardial infarction (AMI)]. The purpose of this study is to explore the significance of Treg/Th17 ratio in early diagnosis ...
Wu Xiaoli X Department of Neurology, Shengjing Hospital of China Medical University, Shenyang, 110021, China, - - 2014
We here in describe a case of hypereosinophilic syndrome (HES) with acute cerebral infarction in a watershed distribution with lesions of the carotid artery but no damage to the endocardium or myocardium. A 62-year-old Chinese man complained of left-sided hemiparesis. Brain MR showed multiple areas of acute ischemia. The eosinophil ...
Otsuka Fumiyuki F Cardiovascular Pathology Inc., 19 Firstfield Road, Gaithersburg, MD 20878, - - 2014
In published post-mortem pathological studies, more than two-thirds of acute coronary events are associated with the rupture of lipid-rich, voluminous, and outwardly remodelled plaques covered by attenuated and inflamed fibrous caps in the proximal part of coronary arteries. Superficial erosion of the plaques is responsible for most of the remaining ...
Kwon Hyung-Jin HJ Department of Family Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, - - 2014
Acute esophageal necrosis is uncommon in the literature. Its etiology is unknown, although cardiovascular disease, hemodynamic compromise, gastric outlet obstruction, alcohol ingestion, hypoxemia, hypercoagulable state, infection, and trauma have all been suggested as possible causes. A 67-year-old female underwent a coronary angiography (CAG) for evaluation of chest pain. CAG findings ...
Piccoli Giorgina B GB SS Nefrologia, Department of Medical and Biological Sciences, ASOU san Luigi Gonzaga, University of Turin, Turin, Italy. Electronic address: - - 2014
Patients with fever, flank pain, and dysuria frequently are encountered in the emergency department. Acute pyelonephritis is the most likely diagnosis; however, its clinical and radiologic presentation consistently overlap with that of acute renal infarction. Ultrasound is unable to distinguish early infarction from nonabscessed acute pyelonephritis. Hence, computed tomography or ...
Inoue Takumi T Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, - - 2014
The consequences of acute strut malapposition in everolimus-eluting stents (EES) are unknown. This study investigated the impact of strut-vessel (S-V) distance and plaque type underneath acute strut malapposition on the mid-term vessel response in EES. Twenty-nine patients (35 EES) underwent optical coherence tomography (OCT) immediately after percutaneous coronary intervention and ...
Mueller Matthias M Department of Internal Medicine III, Cardiology, University Hospital Heidelberg, - - 2014
We sought to evaluate the prognostic impact of absolute and relative kinetic changes of high-sensitivity cardiac Troponin T (hs-cTnT) in comparison to baseline hs-cTnT elevations for risk stratification in acute coronary syndrome (ACS) and non-ACS conditions with increased hs-cTnT. hs-cTnT was measured serially in patients presenting with acute symptoms to ...
Vervaat F E FE Department of Cardiology, University Hospital Maastricht, Maastricht, the Netherlands. Electronic address: - - 2014
The myocardial area at risk (MaR) is an important aspect in acute ST-elevation myocardial infarction (STEMI). It represents the myocardium at the onset of the STEMI that is ischemic and could become infarcted if no reperfusion occurs. The MaR, therefore, has clinical value because it gives an indication of the ...
Herrmann Joerg J Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, - - 2014
The clinical outcome of acute cardiovascular events may be more favorable in patients with a high body mass index (BMI), although obesity increases the risk for cardiovascular diseases. The authors sought to define the association between BMI and acute and long-term outcome of patients presenting within 12 hours of ST-segment myocardial ...
Sederholm Magnus M Karolinska Institutet, 171 77 Stockholm, Sweden. Electronic address: - - 2014
The continuous change of the ST and QRS vectorcardiograms reflect the underlying ischemic event, and can be used as a tool in the management of the acute event. It also reflects reperfusion, and can guide the clinician on when and how to intervene. Continuous vectorcardiography has proven to add prognostic ...
Yokota Takashi T aDepartment of Cardiology, Hirosaki University Graduate School of Medicine, Hirosaki, 036-8562 Japan bDepartment of Cardiology and Respiratory Medicine, Aomori City Hospital, Aomori, 030-0821 Japan cSecond Department of Internal Medicine, Goshogawara City Seihoku Central Hospital, Goshogawara, 037-0053 Japan dDepartment of Cardiology, Hachinohe City Hospital, Hachinohe, 031-8555 Japan eDepartment of Cardiology and Respiratory Medicine, Aomori Rosai Hospital, Hachinohe, 031-8551 - - 2014
Matrix metalloproteinase (MMP) plays a critical role in the development of ventricular remodeling after acute myocardial infarction (AMI). Imidapril, an angiotensin-converting enzyme inhibitor, has been shown to inhibit MMP activity. We investigated whether imidapril inhibits plasma MMP activities and attenuates ventricular remodeling in patients with AMI comparatively with enalapril. We ...
Moriyama Noriaki N Department of Cardiovascular Medicine, National Cerebral and Cardiovascular - - 2014
Background: Acute kidney injury (AKI) and acute hyperglycemia are associated with unfavorable outcomes. The impact of acute hyperglycemia on the development of AKI after acute myocardial infarction (AMI), however, remains unclear. This study was undertaken to assess the relationship between admission glucose and incidence of AKI after AMI. Methods and Results: This ...
Snyder Matthew J MJ Nellis Family Medicine Residency Program, Nellis Air Force Base, NV, - - 2014
Acute pericarditis, inflammation of the pericardium, is found in approximately 5% of patients admitted to the emergency department for chest pain unrelated to acute myocardial infarction. It occurs most often in men 20 to 50 years of age. Acute pericarditis has a number of potential etiologies including infection, acute myocardial ...
Al-Adhami Ahmed A Department of Transplantation and Mechanical Circulatory Support, Golden Jubilee National Hospital, Glasgow, United Kingdom; Department of Bioengineering, University of Strathclyde, Glasgow, United - - 2014
We review the journey to myocardial and neurologic recovery of a 42-year-old mother with severe acute cardiogenic shock and multiorgan failure after extensive subarachnoid hemorrhage, who was salvaged successfully using a CentriMag short-term biventricular assist device.
Makhija Neeti N Department of Cardiac Anaesthesia, Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, - - 2014
A 62 year old female with severe mitral stenosis, large left atrial ball thrombus and acute mesenteric ischemia emergently underwent mitral valve replacement, left atrial clot removal and emergency laparotomy for mesenteric ischemia. Peri-operative management issues, particularly, the anesthetic challenges and the role of transesophageal echocardiography are discussed.
Casier Isabelle - - 2014
Cannabis is a frequently used recreational drug that potentially imposes serious health problems. We report three cases where recent and/or chronic use of marijuana led to severe cardiac dysfunction. All three patients collapsed at home and required cardiopulmonary resuscitation (CPR) with initial restoration of spontaneous circulation (ROSC). The mechanism of ...
De Paula José Guilherme Rodrigues - - 2014
In the clinical scenario of ST-segment elevation acute myocardial infarction, several patients with multivessel coronary atherosclerotic disease are discharged without a defined strategy to monitor the residual atherosclerotic lesions. The clinical endpoints evaluated were cardiovascular death, symptoms of angina pectoris, rehospitalization for a new acute coronary syndrome, and the necessity ...
Dutt Debleena Pain DP Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, New York, - - 2014
The Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) I classification encompasses patients with varying clinical presentations and prognoses. The purpose of this review is to discuss four sub-classifications of cardiogenic shock patients (acute myocardial infarction, acute decompensated heart failure, biventricular failure, and myocarditis), and explore management considerations for these ...
Fakhri Yama Y Department of Cardiology, Rigshospitalet, University Hospital, Copenhagen, Denmark. Electronic address: - - 2014
This review summarizes the electrocardiographic changes during an evolving ST segment elevation myocardial infarction and discusses associated electrocardiographic scores and the potential use of these indices in clinical practice, in particular the ECG scores developed by Anderson and Wilkins estimating the acuteness of myocardial ischemia and Sclarovsky-Birnbaum's grades of ischemia ...
Gili Miguel M Unidad de Gestión Clínica de Medicina Preventiva, Vigilancia y Promoción de la Salud, Hospital Universitario Virgen Macarena, Seville, Spain; Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Seville, Spain. Electronic address: - - 2014
To investigate the relationship between the prevalence of cocaine use disorders and acute myocardial infarction in patients aged ≥ 18 years and to estimate the influence of cocaine use disorders on mortality, excess length of stay, and overexpenditure among hospitalized patients with acute myocardial infarction. Retrospective study of the minimum ...
Tan Shengyu S Department of Geriatrics, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. - - 2014
Baicalein, a flavonoid purified from the root of Scutellaria baicalensis Georgi, is well known for its anti‑inflammatory and anti‑oxidative properties. The present study aimed to evaluate the cardioprotective effect of baicalein in a rat model of acute myocardial infarction and investigate the potential molecular mechanisms of this effect. The acute myocardial ...
Kosuge Masami M Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan. Electronic address: - - 2014
Takotsubo cardiomyopathy (TC) is a recently recognized novel cardiac syndrome characterized by transient left ventricular dysfunction without obstructive coronary disease, electrocardiographic (ECG) changes (ST-segment elevation and/or negative T wave) or elevated cardiac enzymes. Because the clinical features and ECG findings of TC mimic those of anterior acute myocardial infarction (AMI) ...
Siddiqi Nishat N School of Medicine and Dentistry, University of Aberdeen, Aberdeen AB25 2ZD, - - 2014
Despite prompt revascularization of acute myocardial infarction (AMI), substantial myocardial injury may occur, in part a consequence of ischaemia reperfusion injury (IRI). There has been considerable interest in therapies that may reduce IRI. In experimental models of AMI, sodium nitrite substantially reduces IRI. In this doubleblind randomized placebo controlled parallel-group ...
Costa Cátia C Serviço de Cardiologia, Hospital Distrital de Santarém, Santarém, Portugal. Electronic address: - - 2014
Factor VIII is a clotting factor that plays a crucial role in the coagulation cascade. Above-normal levels are found in 11% of the general adult population. Various studies have established a causal association between elevated factor VIII and venous thrombosis; some studies also suggest a relation with arterial thrombosis, particularly ...
Thang Nguyen Dang ND Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address: - - 2014
The aims of this study were (a) to determine the prehospital prevalence of electrocardiographic (ECG) signs of acute myocardial ischemia in patients with suspected acute coronary syndrome and (b) to describe the relationships between the various ECG patterns and the diagnosis of acute myocardial infarction (AMI) and outcomes. Prospective cohort ...
Robertson Jason O JO Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, - - 2014
This study sought to evaluate the short- and long-term outcomes for smokers with non-ST-segment elevation acute coronary syndromes (NSTE-ACS). Smoking has been associated with the "paradox" of reduced mortality after acute myocardial infarction (MI). This is thought to be due to favorable baseline characteristics and less diffuse coronary artery disease ...
Dullaart Robin P F RP Department of Endocrinology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, Groningen 9700 RB, The Netherlands. Electronic address: - - 2014
The cholesterol esterifying enzyme, lecithin:cholesterol acyltransferase (LCAT), plays a key role in HDL maturation and remodeling. Myeloperoxidase (MPO) may compromise LCAT enzymatic activity. We tested the extent to which plasma LCAT activity is altered in acute myocardial infarction (MI) in conjunction with abnormal MPO levels. We also assessed the impact ...
Ross David W - - 2014
Abstract Acute coronary syndrome and myocardial infarction have been described to present with atypical symptoms in certain subsets of patients. However, these subsets commonly do not include middle-aged males with a paucity of underlying medical conditions. We present a very unique case of acute coronary syndrome in a 53-year-old male, ...
Dullaart Robin P F RP Department of Endocrinology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands. Electronic address: - - 2014
Intrinsic functional properties of high density lipoproteins (HDL) are considered to be physiologically important for atheroprotection. We compared the HDL anti-inflammatory capacity between patients with acute myocardial infarction (MI) and patients with non-cardiac chest pain, and prospectively determined the association of new major adverse cardiovascular events (MACE) with this metric ...
Nemoto Naohiko N Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan. Electronic address: - - 2014
Preprocedural chronic kidney disease and contrast-induced acute kidney injury are predictors of in-hospital death and long-term mortality. However, neither the time course of kidney function after percutaneous coronary intervention (PCI) nor the relation between the time course of kidney function and prognosis has been adequately studied. We studied 531 patients ...
Agewall Stefan S Department of Cardiology, Oslo University Hospital Ullevål, and Institute of Clinical Sciences, University of Oslo, Oslo, Norway, - - 2014
Detection of a rise and/or fall of cardiac troponin (cTn) is the cornerstone in the diagnosis of myocardial infarction (MI). For the acute risk, it is hypothesized that cTn mirrors activated coagulation and platelet reactivity and indicates the presence of a ruptured plaque, which may help to identify patients at ...
Veillet-Chowdhury Mahdi M Division of Cardiovascular Disease, Department of Medicine, Stony Brook University Medical Center , Stony Brook, NY , - - 2014
Abstract Takotsubo cardiomyopathy can occur after acute mental or physical stress, subarachnoid hemorrhage, ischemic stroke, major head trauma, acute medical illness or acute pheochromocytoma crisis. It is characterized by transient systolic dysfunction of the apical and/or midventricular segments in patients without epicardial coronary artery disease. The condition occurs most commonly ...
Naaijkens B A BA Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, - - 2014
The majority of patients survive an acute myocardial infarction (AMI). Their outcome is negatively influenced by post-AMI events, such as loss of viable cardiomyocytes due to a post-AMI inflammatory response, eventually resulting in heart failure and/or death. Recent pre-clinical animal studies indicate that mesenchymal stem cells derived from adipose tissue ...
Turfan Murat - - 2014
Previous studies have demonstrated the role of inflammation in acute heart failure. The neutrophil-to-lymphocyte ratio was found to be a useful inflammatory marker for predicting adverse outcomes. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would be associated with increased mortality in acute heart failure patients. The study cohort consisted of ...
Lansky Alexandra J AJ Division of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut. Electronic address: - - 2014
This study evaluated the impact of nonculprit vessel myocardial perfusion on outcomes of non-ST-segment elevation acute coronary syndromes (NSTE-ACS) patients. ST-segment elevation myocardial infarction patients have decreased perfusion in areas remote from the infarct-related vessel. The impact of myocardial hypoperfusion of regions supplied by nonculprit vessels in NSTE-ACS patients treated ...
Gupta Vishal V Department of Endocrinology, Jaslok Hospital and Research Centre, Mumbai, - - 2014
We describe a male patient who presented with sudden onset severe headache and right sided ptosis that was diagnosed to be secondary to pituitary apoplexy on the background of diabetes mellitus. This was complicated by left ventricular failure and acute coronary syndrome. The case highlights the importance of considering hypocortisolism/hypopituitarism ...
Teegala Ramesh R Department of Neurosurgery, Alluri Sita Ramaraju Academy of Medical Sciences (ASRAM), Eluru, - - 2014
Neurocysticercosis is the commonest parasitic disease of the human central nervous system. The incidence of intra ventricular form of neurocysticercosis (NCC) is less common accounting 10-20% that of total central nerve system cysticercosis. Intra ventricular NCC is complicated due, to its high incidence of acute hydrocephalus caused by ball valve ...
Kipp Ryan R University of Wisconsin School of Medicine and Public Health, Division of Cardiovascular Medicine, Department of Medicine, 600 Highland Ave, Madison, WI, - - 2014
Acute right ventricular failure can lead to severe cardiogenic shock and death. Recovery may be achieved with early supportive measures. In many patients, intravenous fluid and inotropic resuscitation is inadequate to improve cardiac output. In these cases, percutaneous mechanical assist may provide a non-surgical bridge to recovery. Herein, we describe ...
Di Diego José M JM Masonic Medical Research Laboratory, Utica, NY. Electronic address: - - 2014
The electrocardiogram (ECG) is an essential tool for the diagnosis of acute myocardial ischemia in the emergency department, as well as for that of an evolving acute myocardial infarction (AMI). Changes in the surface ECG in leads whose positive poles face the ischemic region are known to be related to ...
Atar Dan D Department of Cardiology B, Oslo University Hospital Ullevaal, and Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, - - 2014
The impact of an acute coronary syndrome (ACS) event, such as an acute myocardial infarction (MI), is not limited to the acute management phase; patients face an elevated risk of residual atherothrombotic events that commonly requires chronic management for months or even years. Significant advances have been made in both ...
Figini F F San Raffaele Scientific Insitute, Milan, Italy - - - 2014
In a significant proportion of percutaneous coronary interventions (PCI) performed in the setting of acute myocardial infarction, despite apparently adequate restoration of blood flow in the target epicardial vessel, optimal myocardial reperfusion at tissue level is not achieved. This phenomenon, defined as no-reflow, has been consistently associated with negative outcomes; ...
Madhavan Mahesh V MV NewYork-Presbyterian Hospital and the Columbia University Medical Center, New York, New - - 2014
The synergy between percutaneous coronary intervention (PCI) with Taxus and cardiac surgery (SYNTAX) score (SS) has prognostic utility for ischemic outcomes in patients undergoing PCI. Acute kidney injury (AKI) after PCI has been demonstrated to be associated with adverse outcomes. However, the relation between the SS and AKI after PCI ...
Ozaki Yuichi Y Department of Cardiovascular Medicine, Wakayama Medical - - 2014
Some patients with acute myocardial infarction (AMI) have a poor prognosis due to left ventricular remodeling (LVR), resulting in the recurrence of congestive heart failure even when therapy with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II type 1 receptor blockers (ARBs) has been initiated. We investigated the effect of early ...
Fukushima Noritoshi N Department of Cardiology, Tokyo Women's Medical University, Tokyo, - - 2014
To determine whether adequate myocardial perfusion status after transluminal recanalization is associated with prompt improvement of QT dispersion (QTd). Transluminal recanalization of the infarct-related coronary artery in acute myocardial infarction aims to promptly restore myocardial perfusion, to maximize electrical and mechanical recovery. QTd represents the heterogeneity of ventricular repolarization, which ...
Wang Bin B Department of Cardiac Surgery ICU, Capital Medical University affiliated Beijing Anzhen Hospital, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, - - 2014
To analyse risk factors for early acute cerebrovascular accidents following off-pump coronary artery bypass grafting (OPCAB) in patients with stroke history, and to propose preventive measures to reduce the incidence of these events. A total of 468 patients with a history of stroke underwent OPCAB surgery in Beijing Anzhen Hospital ...
Velibey Yalcin Y Bitlis State Hospital, Department of Cardiology, Bitlis, Turkey. Electronic address: - - 2014
A 62-year old patient with a history of chronic anemia associated with malabsorption secondary to short gut syndrome, experienced acute chest pain the second hour after the transfusion of a crossmatch-compatible erythrocyte suspension. His electrocardiogram (ECG) revealed widespread ST-segment depressions and he had an elevated troponin level. Laboratory findings and ...
Ersbøll Mads M Department of Cardiology, The Heart Centre, University Hospital Rigshospitalet, Copenhagen, Denmark. Electronic address: - - 2014
Renal dysfunction in patients with acute myocardial infarction (MI) is an important predictor of short- and long-term outcome. Cardiac abnormalities dominated by left ventricular (LV) hypertrophy are common in patients with chronic renal dysfunction. However, limited data exists on the association between LV systolic- and diastolic function assessed by comprehensive ...
Im Eui E From the Division of Cardiology, Severance Cardiovascular Hospital (E.I., B.-K.K., Y.-G.K., D.-H.S., J.-S.K., D.C., Y.J., M.-K.H.) and Severance Biomedical Science Institute (Y.J., M.-K.H.), Yonsei University College of Medicine, Seoul, - - 2014
We investigated the incidences, predictors, and clinical outcomes of acute and late stent malapposition detected by optical coherence tomography (OCT) after drug-eluting stent implantation. We analyzed the OCT images from 351 patients with 356 lesions who received poststent and follow-up OCT examinations. Acute stent malapposition was observed in 62% of ...
Akuzawa Nobuhiro - - 2014
Viral myocarditis presents with various symptoms, including fatal arrhythmia and cardiogenic shock, and may develop chronic myocarditis and dilated cardiomyopathy in some patients. We report here a case of viral myocarditis with liver dysfunction and pancreatitis. A 63-year-old man was admitted to our hospital with dyspnea. The initial investigation showed ...
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