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Climov Daniela - - 2014
Biofeedback is a self-regulation therapy by which the patient learns how to optimize the functioning of his autonomic nervous system. It has been applied to patients with various cardiovascular disorders. The purpose of this study was to investigate the practical feasibility and the psychophysiological effects of biofeedback applied to heart ...
Husain Nazia - - 2014
Echocardiographic evaluation of systolic function in patients with single right ventricles (SRV) is important but remains challenging. Minimal data exist correlating echocardiographic indices with catheterization data in this population. The goal of this study was to evaluate which echocardiographic measurement correlated best with dP/dt (max) obtained by cardiac catheterization in ...
Rosenblatt Jeffrey J Maine Medical Center, Department of Cardiac Services, Tufts University School of Medicine, 22 Bramhall St, 119 Gannett Drive, Portland, ME, 04106, USA, - - 2014
Regadenoson is a selective A2A receptor agonist approved for use as a pharmacologic stress agent for myocardial perfusion imaging after several multicenter trials demonstrated its equivalence in diagnostic accuracy for the detection of coronary artery disease and a decreased incidence of serious side effects as compared to adenosine. Recently, the ...
Dellegrottaglie S S Division of Cardiology, Ospedale Medico-Chirurgico Accreditato Villa dei Fiori, C.so Italia, 157, 80011, Naples, Acerra, Italy, - - 2014
We report the case of a 32-year-old male with Chlamydia trachomatis infection and admitted with chest pain, signs of myocardial damage and coronary arteries free from significant atherosclerotic disease. Cardiac magnetic resonance imaging (MRI) documented imaging patterns of myocardial involvement suggestive of acute myocarditis, and repeated cardiac MRI examinations were ...
Lemkes Jorrit J Department of Cardiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, - - 2014
Patients with chest pain and a prehospital ST-segment elevation myocardial infarction (STEMI) are preferably treated with immediate percutaneous coronary intervention (PCI). However, patients with normalization of symptoms and ST-segment elevation upon hospital arrival (transient STEMI) received inconsistent therapy due to logistic reasons and the absence of evidence or explicit guidelines. ...
Chow Grant V GV Division of Cardiology, Johns Hopkins Medical Institutions, The Johns Hopkins University School of Medicine; Baltimore, - - 2014
Patients with acute MI, left bundle branch block (LBBB), and marked LV de-compensation suffer nearly 50% early mortality. Whether CRT improves hemodynamic status in this condition is unknown. We tested CRT in this setting, using a canine model of delayed lateral wall activation combined with 2-hours of coronary artery occlusion-reperfusion. ...
Benezet-Mazuecos Juan J Department of Cardiology, Hospital Universitario Fundación Jiménez Díaz-IDCsalud, Universidad Autónoma de Madrid, Madrid, - - 2014
Assessment of the prevalence of silent paroxysmal atrial fibrillation (AF) represents a challenge, since the arrhythmia may be brief, completely asymptomatic, and difficult to detect. Lack of symptoms from AF should not be equated to lack of risk of thromboembolic complications. Today's cardiac implantable electronic devices (CIED) diagnostics include system ...
Backhoff David D Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University, Robert-Koch-Str 40, 37075, Göttingen, - - 2014
Years and decades after the Mustard atrial switch repair for d-Transposition of the great arteries, there is a subset of patients at increased risk for sudden cardiac death due to ventricular tachyarrhythmias. To date, little is known about indications, efficacy and benefit of internal cardioverter defibrillator (ICD) therapy indication in ...
Genet Martin M - - 2014
Ventricular wall stress is believed to be responsible for many physical mechanisms taking place in the human heart, including ventricular remodeling, which is frequently associated with heart failure. Therefore, normalization of ventricular wall stress is the cornerstone of many existing and new treatments for heart failure. In this paper, we ...
Matsushita Kunihiro K From the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (K.M., Y.S., S.H.B., M.W., J.C.); Department of Medicine and Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison (B.C.A.); Department of Medicine, Section of Atherosclerosis and Vascular Medicine, Baylor College of Medicine, and the Methodist DeBakey Heart and Vascular Center, Houston, TX (R.C.H., C.M.B.); Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.D.S.). - - 2014
Traditional predictors suboptimally predict cardiovascular disease (CVD) in individuals with chronic kidney disease (CKD). This study compared 5 nontraditional cardiac and kidney markers on the improvement of cardiovascular prediction among those with CKD. Among 8622 participants aged 52 to 75 years in the Atherosclerosis Risk in Communities (ARIC) Study, cardiac ...
Esper Stephen A SA UPMC, Pittsburgh, PA, - - 2014
The techniques and equipment of cardiopulmonary bypass (CPB) have evolved over the past 60 years, and numerous numbers of cardiac surgical procedures are conducted around the world using CPB. Despite more widespread applications of percutaneous coronary and valvular interventions, the need for cardiac surgery using CPB remains the standard approach ...
Senanayake Eshan L EL Department of Cardiac Surgery, University Hospital Birmingham NHS Foundation Trust, Birmingham, - - 2014
Coronary artery disease in the donor heart is an established cause of early graft failure. However, identification of this before implantation is difficult. Cardiogenic shock associated with significant myocardial infarction during the early postoperative period is rare. Here, we report a case of a 42-year-old man who presented acutely with ...
Martindale Jennifer L JL Emergency Department, State University of New York Downstate, Kings County Hospital, Brooklyn, New - - 2014
To many physicians, hyperkalemia is the first diagnosis ascribed to any patient with end-stage renal disease and abnormal electrocardiographic morphologies or dysrhythmias. A 52-year-old man with end-stage renal disease presented in cardiac arrest. The patient was initially presumed to have hyperkalemia, based on the appearance of wide QRS complexes on ...
Hari Pawan P Division of Cardiology, Loma Linda University Medical Center, Loma Linda, - - 2014
Patent foramen ovale (PFO) is a common variant present in up to 25% of the population. Atrial septal defect (ASD) is a direct communication between the 2 atrial chambers, of which the ostium secundum variety is the most common. This manuscript is an in depth review of the complex atrial ...
Blei Francine F Vascular Birthmark Institute, St. Luke's Roosevelt Hospital, New York, New - - 2014
There is no uniform pretreatment cardiac evaluation for infants treated with oral propranolol, which is now the drug of choice for hemangiomas of infancy requiring systemic medical intervention. The aim of this study was to report and evaluate the findings of pretreatment cardiac evaluation. Data were reviewed for patients evaluated ...
Lin Kai K Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States. Electronic address: - - 2014
To test the hypothesis that biomechanical changes are quantitatively related to morphological features of coronary arteries in heart transplant (HTx) recipients. With IRB approval, three-dimensional (3D) magnetic resonance (MR) angiography and two-dimensional (2D) black-blood stead-state free precession (SSFP) MR imaging were performed to image coronary arteries of 36 HTx patients. ...
Kalogeropoulos Andreas P AP Division of Cardiology, Emory University, Atlanta, GA. Electronic address: - - 2014
Inotropes are widely used in hospitalized systolic heart failure (HF) patients, especially those with low systolic blood pressure (SBP) or cardiac index. Also inotropes are considered harmful in nonischemic HF. We examined the association of in-hospital inotrope use with (1) major events (death, ventricular assist device, or heart transplant) and ...
Lynch Thomas L TL Department of Cell and Molecular Physiology, Division of Cardiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, 60153, - - 2014
Cardiac myosin binding protein-C (cMyBP-C) is a regulatory protein of the contractile apparatus within the cardiac sarcomere. Ischemic injury to the heart during myocardial infarction (MI) results in the cleavage of cMyBP-C in a phosphorylation-dependent manner and release of an N-terminal fragment (C0C1f) into the circulation. C0C1f has been shown ...
Huang Lixing L State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen 361005, - - 2014
Growing evidence indicates that polycyclic aromatic hydrocarbons (PAHs) can lead to cardiac hypertrophy and recent research indicates that exposure to low dose crude oil during early embryonic development may lead to impacts on heart health at later life stages. The aim of this study was to evaluate whether exposure during ...
Dhein Stefan S Klinik für Herzchirurgie, Universität Leipzig, Herzzentrum, Struempellstr. 39, 04289, Leipzig, Germany, - - 2014
Mechanical stretch has been shown to provoke arrhythmia. We wanted to analyze ventricular arrhythmia induced by local left ventricular stretch in order to find out, where arrhythmias originate and whether they can be prevented pharmacologically. Isolated rabbit hearts (Langendorff technique) were submitted to increased left ventricular stretch at the left ...
Anderson Robert H RH Institute of Genetic Medicine, Newcastle University, Newcastle, United - - 2014
The past decades have seen immense progress in the understanding of cardiac development. Appreciation of precise details of cardiac anatomy, however, has yet to be fully translated into the more general understanding of the changing structure of the developing heart, particularly with regard to formation of the septal structures. In ...
Pfob Michael M CardioVital Institute of Preventive and Rehabilitation Medicine, Grieskirchnerstraße 49, 4600, Wels, Austria, - - 2014
In patients with coronary heart disease, both arterial stiffness and wave reflections are increased and predict unfavorable cardiovascular events. Cardiac rehabilitation has the goal to reduce risk factors and slow the progression of the disease. The aim of this study was to prospectively determine the impact of an ambulatory cardiac ...
Danese Elisa E Laboratory of Clinical Chemistry and Hematology, University of Verona , Verona , - - 2014
Atrial fibrillation (AF) is the most common among the severe cardiac arrhythmias and carries a significant risk of mortality and morbidity in the general population. The most important complication is represented by development of one or more thrombi in the left atrium of the dyskinetic heart, and their successive cerebral ...
Aminzadeh Mohammad A MA Cedars-Sinai Heart Institute, 8700 Beverly Boulevard, Los Angeles, CA 90048, - - 2014
Cardiosphere-derived cells (CDCs) produce regenerative effects in the post-infarct setting. However, it is unclear whether CDCs are beneficial in non-ischaemic dilated cardiomyopathy (DCM). We tested the effects of CDC transplantation in mice with cardiac-specific Gαq overexpression, which predictably develop progressive cardiac dilation and failure, with accelerated mortality. Wild-type mouse CDCs ...
Liu Xinbing X aDepartment of Cardiology, Shanghai Shi Dong Hospital bDepartment of Geriatrics, Shanghai No. 3 People's Hospital cDepartment of Cardiology, An Tu Hospital, Shanghai, - - 2014
The aim of this study was to investigate the effects of a noninvasive positive pressure ventilation therapy on cardiac structure and function in patients with coronary heart disease combined with obstructive sleep apnea/hypopnea syndrome (OSAHS). Eighty patients with coronary heart disease OSAHS were divided randomly into treatment (n=40) and control ...
van Riet Evelien E S EE Julius Center for Health Sciences and Primary care, University Medical Center Utrecht, PO Box 85500, 3508 AB, Utrecht, the - - 2014
The majority of patients with heart failure are diagnosed in primary care, but underdiagnosis is common. Shortness of breath is a prevalent complaint of older persons and one of the key symptoms of heart failure. We assessed the prevalence of unrecognized heart failure in elderly patients presenting to primary care ...
Cetin Metin M Clinic of Cardiology, Çerkezköy State Hospital; Tekirdağ-Turkey. - - 2014
Vitamin D status has been implicated in the pathophysiology of heart failure (HF). The aim of this study was to investigate the association between vitamin D levels with heart rate variability and heart rate turbulence in patients with heart failure whom had ischemic and non-ischemic dilated cardiomyopathy. Study designed as ...
de Vette Liesbeth C LC Liesbeth C de Vette, Jasper J Brugts, Jacky S McGhie, Jolien W Roos-Hesselink, Department of Cardiology, Erasmus MC, 230 3015 CE Rotterdam, The - - 2014
M Ebstein is usually diagnosed in early childhood or adolescence. The young woman in our case complainted of fatigue and shortness of breath, on physical examination she showed signs of heart failure with raised central venous pressure, palpable liver, an a cardiac murmer. Based on these findings she should have ...
Penna Claudia C Dipartimento di Scienze Cliniche e, Biologiche Università di Torino, Ospedale S. Luigi, Regione Gonzole, 10, 10043, Orbassano, TO, - - 2014
Melusin is a muscle-specific protein which interacts with β1 integrin cytoplasmic domain and acts as chaperone protein. Its overexpression induces improved resistance to cardiac overload delaying left ventricle dilation and reducing the occurrence of heart failure. Here, we investigated possible protective effect of melusin overexpression against acute ischemia/reperfusion (I/R) injury ...
Mei Zhusong Z Key laboratory of stress medicine, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Haidian District, Beijing, China, - - 2014
Myocardial hypertrophy is an adaptive response of the heart to work overload. Pathological cardiac hypertrophy is usually associated with the ultimate development of cardiac dysfunction and heart failure. The mitochondria have an important function in the development of cardiac hypertrophy. However, mitochondrial adaptations to hypertrophic stimulus remain ambiguous. A rat ...
Kodama Ken K Department of Thoracic Surgery, Yao Municipal Hospital, 1-3-1 Ryuge-cho, Yao, Osaka, 581-0069, Japan, - - 2014
We experienced an excision of the mediastinal tumor located in left anterior mediastinum found in a 21-year-old woman. The histologic diagnosis of Hodgkin's lymphoma was obtained. After operation, she was treated with mantle field radiotherapy (total 42 Gy) followed by chemotherapy. At 43-year old, she developed constrictive pericarditis and heart failure ...
Christensen Thomas Emil TE Department of Clinical Physiology, Nuclear Medicine & PET, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen E, Denmark, - - 2014
In patients with heart failure (HF) due to coronary disease, a combined evaluation of perfusion and glucose metabolism by cardiac single photon emission computed tomography (SPECT)/positron emission tomography (PET) can be used to distinguish viable from non-viable myocardium, and current guidelines recommend cardiac SPECT and fluorodeoxyglucose (FDG) PET for viability ...
Kalam Kashif K Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, - - 2014
Global longitudinal strain (GLS) is a robust, well validated and reproducible technique for the measurement of LV longitudinal deformation. We sought to assemble evidence that GLS is an accurate marker in predicting cardiovascular outcomes, compared to LVEF. We undertook a systematic review of the evidence from observational studies which compared ...
Mitsuyama Hirofumi H Hokkaido University Graduate School of - - 2014
Background: Action potential duration alternans (APD-ALT), defined as long-short-long repetitive pattern of APD, potentially leads to lethal ventricular arrhythmia. However, the mechanisms of APD-ALT in the arrhythmogenesis of cardiac hypertrophy remain undetermined. Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is known to modulate the function of cardiac sarcoplasmic reticulum and play an ...
Böhm Michael M Universitätsklinikum des Saarlandes, Homburg/Saar, - - 2014
Higher heart rate is associated with poorer outcomes in patients with heart failure and reduced ejection fraction (HF-REF). Less is known about the association between heart rate and outcomes in patients with heart failure and preserved ejection fraction (HF-PEF). Therefore, we examined the relationship between heart rate and outcomes in ...
Mittal Suneet S Arrhythmia Institute, Valley Health System, Columbia University College of Physicians and Surgeons, New York, NY, Ridgewood, - - 2014
This study determined whether the presence of non-sustained ventricular tachycardia (NSVT) was predictive of clinical events in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy) patients treated with cardiac resynchronization therapy-defibrillator (CRT-D). We analyzed 24-hour Holters for the presence of NSVT. Patients were then stratified by the etiology (ischemic or ...
Holmberg Fredrik Eo - - 2014
Abstract Objectives:The objective was to investigate potential protective effects of two conditioning methods, on myocardial ischemic- and reperfusion injury in relation to cardiac surgery. Design:68 patients were randomly assigned to either a control group (n=23), a remote ischemic preconditioning group (n=23) or a glucagon-like peptide 1 analogue group (n=22). The ...
Maurin O O Brigade des sapeurs-pompiers de Paris, 1 place Jules-Renard, 75017 - - 2014
Intraosseous infusion is increasingly used as an alternative to intravenous infusion. It is recommended for the cardiac arrest of a child in the first instance and after two failed attempts of intravenous infusion in the cardiac arrest of adults. Its rapid use and its low failure rate justify its use ...
Nagai Toshiyuki - - 2014
Cardiac death is the leading cause of mortality associated with sarcoidosis in Japan. However, the involvement of sarcoidosis infiltration often remains undetected. Recently, late gadolinium enhancement with cardiovascular magnetic resonance (LGE-CMR) imaging has been introduced for the detection of myocardial infiltrative disease, as it enables the detection of even minor ...
Carmo Lucas S LS Department of Pathology, Ribeirão Preto Medical School, University of São Paulo, - - 2014
We report an autopsy case of a 24-year-old man with diagnoses of advanced alcoholic liver cirrhosis, portal hypertension, and esophageal variceal bleeding that presented extensive myocardial infarction after treatment with terlipressin. On postmortem examination the cut surface of the heart presented myocardial infarction implicating the left ventricle free wall, apex ...
Fumagalli Francesca F IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milan, - - 2014
During ischemia, enhancement of the "late Na(+) current" (INaL) contributes to intracellular Ca(2+) overload. Dysregulation of intracellular Ca(2+) homeostasis plays a critical role in the pathophysiology of cardiac arrest and cardiopulmonary resuscitation (CPR), leading to ventricular arrhythmias and left ventricle (LV) dysfunction. We investigated the effects of the INaL blocker ...
Junttila M Juhani MJ Medical Research Center Oulu, University of Oulu and University Hospital of Oulu, Finland. Electronic address: - - 2014
Early repolarization (ER) in the inferior/lateral leads predicts mortality, but it is not known whether ER is a specific sign of increased risk for arrhythmic events. We studied the association of ER and arrhythmic events and non-arrhythmic morbidity and mortality. We assessed the prognostic significance of ER in a community-based ...
Moretti Claudio C aDivision of Cardiology, Città della Salute e della Scienza, University of Turin, Turin bDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy cInstitut Cardiovasculaire Paris Sud, Hôpital Jacques Cartier, Paris, France dDivision of Cardiology, Presidio Ospedaliero Misericordia, Grosseto eDivision of Cardiology, Azienda Ospedaliera Senese, Siena fDivision of Cardiology, Azienda Ospedaliera S. Luigi Gonzaga, Orbassano gDivision of Cardiology, Ospedale Maria Vittoria hDivision of Cardiology, San Giovanni Bosco Hospital, Turin iDivision of Cardiology, Istituto Clinico Humanitas, Rozzano, Milan, Italy jNanjing First Hospital, Nanjing Medical University, Nanjing, China kDivision of Cardiology, Pederzoli Hospital, Riva del Garda, - - 2014
Contrast-induced nephropathy (CIN) and periprocedural myocardial infarction (PMI) represent frequent complications of percutaneous coronary intervention (PCI) and negatively impact subsequent length of hospitalization, costs of adjunctive diagnostic-therapeutic measures and mid-term cardiovascular events. The aim of the EURO-CRIPS trial is to test whether remote ischemic preconditioning (RIPC) may reduce the incidence ...
Crea P P Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy, - - 2014
Obesity rates are rising worldwide. Often obesity is associated with hypertension leading to an increased cardiovascular risk. Both obesity and hypertension induce several modifications in cardiac structure and function, particularly atrial and ventricular remodeling is a common finding shared by these two conditions. It has been demonstrated obesity leads to: ...
Ramchandra Rohit R University of Auckland - - 2014
Heart failure (HF) is associated with increased cardiac and renal sympathetic drive, which are both independent predictors of poor prognosis. A candidate mechanism for the centrally mediated sympatho-excitation in HF is reduced synthesis of the inhibitory neuromodulator nitric oxide (NO), resulting from down-regulation of neuronal NO synthase (nNOS). We therefore ...
Açıkgöz Eser E Cardiology Department, Gazi University Faculty of Medicine, Ankara, - - 2014
Fragmented QRS (fQRS) is an indicator of nonhomogeneous ventricular activity caused by myocardial fibrosis. Aortic stenosis (AS) is known to be a cause of myocardial fibrosis. We aimed to investigate the relationship of fQRS with severity of AS, echocardiographic, and electrocardiographic findings, and development of atrial fibrillation and manifest heart ...
Koranne Ketan P KP Cardiology Fellow, Division of Cadiovascular Medicine, Department of Internal Medicine, University of Texas Health Science Center at - - 2014
A 74 year old woman with paroxysmal atrial fibrillation underwent left atrial appendage (LAA) exclusion with a LARIAT snare device. Transesophageal echocardiogram one month later demonstrated a left atrial thrombus at orifice of the completely occluded left atrial appendage, that subsequently resolved with two months of anticoagulation. This case highlights ...
Sonoda Kazumasa K Division of Cardiology, Department of Medicine, Nihon University School of - - 2014
Background:Atrial fibrillation (AF) causes atrial electrical and structural remodeling, which are linked to recurrence of AF after ablation. Atrial fibrillatory cycle length (AFCL) and AF wall motion velocity (AFW-V) obtained by tissue velocity imaging (TVI) might characterize such atrial electrical and structural remodeling. The purpose of this study was to ...
Stosovic Milan D MD Clinic of Nephrology, Clinical Center of Serbia , Belgrade , Serbia - - 2014
Abstract Background: Serum cardiac troponin T (cTnT) is a valuable marker of ischemic heart disease (IHD) and left ventricular hypertrophy, as well as a mortality predictor in hemodialysis populations. We compared the value of cTnT, creatinine kinase (CK)-MB mass and myoglobin as mortality predictors in our hemodialysis patients and evaluated ...
Ma Sai S Department of Cardiology, Chinese PLA General Hospital, 28# Fuxing Street, Beijing, 100852, China; Department of Cardiology, Xijing Hospital,Fourth Military Medical University, 127# Changle West Road, Xi`an, Shaanxi, 710032, - - 2014
Autophagy is an intracellular process responsible for damaged or unnecessary proteins and organelles degradation. In the heart, autophagy occurs at basal level and dysregulated autophagy is associated with a variety of cardiovascular diseases. Autophagy is enhanced in ischemia as well as reperfusion phase during cardiac ischemia reperfusion (I/R) injury. More ...
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