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Results 351 - 400 of 6402
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Arslan Müzeyyen M Turgut Ozal University School of Nursing , Ankara, Turkey - - 2014
Abstract Objectives: A recent study showed that cupping had therapeutic effects in rats with myocardial infarction and cardiac arrhythmias. The current studyaimed to investigate the possible useful effects of cupping therapy on cardiac rhythm in terms of heart rate variability (HRV). Materials and methods: Forty healthy participants were included. Classic ...
Sohinki Daniel D University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9047, - - 2014
Atrioventricular junction ablation (AVJA) combined with biventricular (BiV) pacing (AVJA/BiV) is an effective treatment for refractory atrial fibrillation (AF) and rapid ventricular response (RVR) associated with heart failure (HF). This study compared the outcomes between patients with non-ischaemic (DCM) and ischaemic cardiomyopathy (ICM) following AVJA/BiV for AF/RVR.METHODS AND RESULTS: This ...
Petersson Richard R Department of Cardiology, Lund University and Center for Integrative Electrocardiology at Lund University, Lund, - - 2014
Orthogonal P-wave morphology has previously been described in different populations, but its relation to atrial size has not been studied in detail. In this study, we investigated whether atrial size affects P-wave morphology in athletes, who are known to have different degrees of atrial enlargement. A total of 504 healthy, ...
Ahtarovski Kiril Aleksov KA Department of Cardiology, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, - - 2014
Takotsubo cardiomyopathy (TTC) is an entity mimicking acute myocardial infarction, characterized by transient severe systolic heart failure. Echocardiographic studies suggest that diastolic dysfunction is present in TTC at presentation; however, no reports exist regarding the time course of left ventricular (LV) recovery. This study describes the recovery of LV systolic ...
Shetty Anoop K AK Department of Imaging Sciences, Rayne Institute, Kings College London, London SE1 7EH, - - 2014
Alternative forms of cardiac resynchronization therapy (CRT), including biventricular endocardial (BV-Endo) and multisite epicardial pacing (MSP), have been developed to improve response. It is unclear which form of stimulation is optimal. We aimed to compare the acute haemodynamic response (AHR) and electrophysiological effects of BV-Endo with MSP via two separate ...
Ballany Wassim W Division of Adult Cardiology, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, - - 2014
In patients undergoing regadenoson stress SPECT myocardial perfusion imaging (MPI), the impact of the regimented administration of aminophylline on the cardiac-to-extracardiac photon activity ratio is unknown. This is a substudy of the ASSUAGE trial (NCT01250496); a double-blinded, randomized, placebo-controlled clinical trial which investigated the attenuation of regadenoson-related adverse effects using ...
Alwaqfi Nizar R - - 2014
Although temporary cardiac pacing is infrequently needed, temporary epicardial pacing wires are routinely inserted after valve surgery. As they are associated with infrequent, but life threatening complications, and the decreased need for postoperative pacing in a group of low risk patients; this study aims to identify the predictors of temporary ...
Giraud Raphaël R Intensive Care Service, Geneva University Hospitals, Geneva, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland; Geneva Hemodynamic Research Group, Geneva, Switzerland. Electronic address: - - 2014
Survival after cardiac arrest depends on prompt and effective cardiopulmonary resuscitation (CPR). Resuscitative teams are more frequently using mechanical chest compression devices, as documented in physiologic and experimental data, suggesting that these devices are more effective than manual CPR. A 41-year-old male patient presented with an ST-elevation myocardial infarction with ...
Tucci Sara S Department of General Pediatrics, Center for Pediatrics and Adolescent Medicine, University Hospital Freiburg 79106 Freiburg, Germany; Department of General Pediatrics, University Children´s Hospital Duesseldorf, 40225 Duesseldorf, Germany. Electronic address: - - 2014
Hypertrophic cardiomyopathy is a typical manifestation of very long-chain acyl-CoA dehydrogenase deficiency (VLCADD), the most common long-chain β-oxidation defects in humans; however in some patients cardiac function is fully compensated. Cardiomyopathy may also be reversed by supplementation of medium-chain triglycerides (MCT). We here characterize cardiac function of VLCAD-deficient (VLCAD(-/-)) mice ...
Liquori Michael E ME University of Maryland School of Medicine Department of Internal Medicine(1), 22S. Greene St, Baltimore, MD 21201. Electronic address: - - 2014
Background: Heart failure is a syndrome characterized by the inability of the heart to meet the body's circulatory demands. Heart failure is a growing health issue worldwide and the prevalence of heart failure is expected to rise as populations age. Therapies and interventions for a variety of cardiac conditions continue ...
Cheng Nan N Department of Cardiovascular Surgery, Chinese People's Liberation Army General Hospital, Beijing, - - 2014
Robotic cardiac surgery has been proved safe and feasible in dedicated centers. We systematically analyzed the learning curve issues associated with totally endoscopic coronary artery bypass grafting (TECAB) using a stepwise approach by a single surgeon who had successfully performed >650 cases of various types of robotic cardiac surgery at ...
Napodano Massimo M Cardiology Clinic, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy. Electronic address: - - 2014
Large thrombus burden (LTB) lesions in the context of primary percutaneous coronary intervention (p-PCI) have been related to unsuccessful angiographic reperfusion and unfavorable clinical outcomes. However, the hazard of LTB treatment on myocardial damage has not been evaluated. We investigated the impact of LTB on myocardial damage using contrast-enhanced cardiac ...
Robertson Jason O JO Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, St Louis, MO, - - 2014
The effect of atrial fibrillation (AF) on left atrial (LA) function has not been well defined and has been largely based on limited echocardiographic evaluation. This study examined the effect of AF and a subsequent Cox-Maze IV (CMIV) procedure on atrial function. Cardiac magnetic resonance imaging (cMRI) was performed in ...
Giannico Amália Turner AT Department of Veterinary Medicine, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, PR, 80035-050, Brazil, - - 2014
Tonic immobility (TI) is a response to fear or threat by remaining motionless, principally when attacked by predators from which there is no possibility of escape. Thus, here we demonstrate a way of easily reproducing this phenomenon in a laboratory setting and characterize the cardiac electromechanical alterations during TI. We ...
Zhang Caimei C University of Iowa Carver College of Medicine, Iowa City, - - 2014
Cardiac dysfunction in failing hearts of human patients and animal models is associated with both microtubule densification and T-tubule remodeling. Our objective was to investigate whether microtubule densification contributes to T-tubule remodeling and excitation-contraction coupling dysfunction in heart disease. In a mouse model of pressure overload-induced cardiomyopathy by transaortic banding ...
Davies Ryan R RR Nemours Cardiac Center, Nemours/A.I. duPont Hospital for Children, Wilmington, Delaware, United States of - - 2014
Heart failure is a common cause of death in patients with muscular dystrophy. Mechanical support may be an important component of long-term heart failure therapy in these patients. We present a report of a child with muscular dystrophy successfully implanted with a Heartware HVAD.
Wang Jake X JX Bonde Artificial Heart Laboratory, Yale University School of Medicine, New Haven, - - 2014
Left ventricular assist device therapy has radically improved congestive heart failure survival with smaller rotary pumps. The driveline used to power today's left ventricular assist devices, however, continues to be a source of infection, traumatic damage, and rehospitalization. Previous attempts to wirelessly power left ventricular assist devices using transcutaneous energy ...
Meier Pascal P Division of Cardiology, Yale Medical School, New Haven, Connecticut-USA. - - 2014
Unstable coronary artery plaque is the most common underlying cause of acute coronary syndromes (ACS) and can manifest as unstable angina, non-ST segment elevation infarction (NSTE-ACS), and ST elevation myocardial infarction (STEMI), but can also manifest as sudden cardiac arrest due to ischaemia induced tachyarrhythmias. ACS mortality has decreased signi´Čücantly ...
Abhilash S P SP Assistant Professor, Cardiology, Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, - - 2014
Sudden cardiac death (SCD) is an unexpected death due to cardiac causes that occurs in a short time period (generally within 1 h of symptom onset) in a person with known or unknown cardiac disease. It is believed to be involved in nearly a quarter of human deaths, with ventricular fibrillation ...
Israel Carsten W CW Assistant Professor, Dept. of Medicine, Div. of Cardiology, Evangelical Hospital Bielefeld, Burgsteig 13, 33617 Bielefeld, Germany. Electronic address: - - 2014
Worldwide, sudden cardiac death (SCD) is a major problem. It is most frequently caused by ventricular tachyarrhythmias: Monomorphic and polymorphic ventricular tachycardia (VT), torsade de pointes (TdP), and ventricular fibrillation (VF). Beta blockade, ACE inhibition, coronary reperfusion and other treatments have reduced the incidence of VT but pulseless electrical activity (PEA) ...
Goldraich Livia A LA Heart Failure and Cardiac Transplant Group, Cardiovascular Experimental and Molecular Laboratory, Division of Cardiology, Hospital de Clínicas de Porto Alegre , Porto Alegre , Brazil - - 2014
Abstract Context: Elevated plasmatic microRNAs (miRs) are observed in heart failure (HF). However, the cardiac origin of these miRs remains unclear. Objective: We calculated transcoronary gradients of miR-29b, miR-133a and miR-423-5p in 17 outpatients with stable systolic HF and in controls without structural cardiac disease. Materials and methods: MicroRNAs were ...
Latif Muhammad A MA St. John Cardiovascular Research Center, Los Angeles Biomedical Research Institute, Torrance, CA, - - 2014
As laparoscopic surgery is replacing open surgery, similarly computed tomography angiography is replacing invasive conventional cardiac angiography. In the last century, marvelous efforts in research have improved strategies for cure, diagnosis and prevention of fatal human diseases; however, coronary artery disease, as the most prevalent cause of mortality and morbidity ...
Zheng Minjuan M Ultrasound Department, Xijing Hospital, Fourth Military Medical University, Xi'an, - - 2014
This study aimed to evaluate the instantaneous biological response of canine myocardium in vivo to high-intensity focused ultrasound (HIFU) ablation, and thereby determine the feasibility of this method. Left ventricle myocardium HIFU ablation was performed on six dogs at four levels of HIFU energy (acoustic intensity was 3000 W/cm(2) ; ablation ...
Willis Mark M 1. The Alan Richens Welsh Epilepsy Centre, University Hospital of Wales, Heath Park, - - 2014
A 66-year-old man presented following a generalised tonic-clonic seizure and a 1 month history of paroxysmal episodes with autonomic and sensory symptoms. MRI found right medial temporal lobe swelling and high signal. Cardiac telemetry found supra-ventricular tachycardia and prolonged pauses during the paroxysmal episodes. Voltage gated potassium channel (VGKC) antibodies ...
Saguner Ardan M AM 1Department of Cardiology, University Heart Center Zurich, - - 2014
-The value of standard two-dimensional transthoracic echocardiographic (TTE) parameters for risk stratification in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is controversial. -We investigated the impact of right ventricular fractional area change (FAC) and tricuspid annulus plane systolic excursion (TAPSE) for prediction of major adverse cardiovascular events (MACE) defined as ...
Shiba Yuji Y 1Department of Pathology, Center for Cardiovascular Biology, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, - - 2014
Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) were recently shown to be capable of electromechanical integration following direct injection into intact or recently injured guinea pig hearts, and hESC-CM transplantation in recently injured hearts correlated with improvements in contractile function and a reduction in the incidence of arrhythmias. The present study ...
Spoon Daniel B DB Mayo Clinic, Rochester, - - 2014
The impact of changing demographics upon causes of long-term death after percutaneous coronary intervention (PCI) remains incompletely defined. We evaluated trends in cause-specific long-term mortality after index PCI performed at a single center from 1991-2008. Deaths were ascertained by scheduled prospective surveillance. Cause was determined via telephone interviews, medical records, ...
Haack Karla K V KK Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, - - 2014
Cheyne-Stokes respiration and cardiac arrhythmias are associated with increased morbidity and mortality in patients with chronic heart failure (CHF). Enhanced carotid body chemoreflex (CBC) sensitivity is associated with these abnormalities in CHF. Reduced carotid body (CB) nitric oxide and nitric oxide synthase (NOS) levels play an important role in the ...
Rassi Daniela do Carmo DD Faculdade de Medicina, Hospital das Clínicas, Universidade Federal de Goiás, GoiâniaGO, Brasil, Faculdade de Medicina e Hospital das Clínicas da Universidade Federal de Goiás (UFG), Goiânia, GO - - - 2014
Background: Echocardiography provides important information on the cardiac evaluation of patients with heart failure. The identification of echocardiographic parameters in severe Chagas heart disease would help implement treatment and assess prognosis. Objective: To correlate echocardiographic parameters with the endpoint cardiovascular mortality in patients with ejection fraction < 35%. Methods: Study ...
Joyce William W Zoophysiology, Department of Biosciences, Aarhus University, DK-8000 Aarhus C, Denmark; Faculty of Life Sciences, The University of Manchester, M13 9PT, UK. Electronic address: - - 2014
The few and fragmentary studies on purinergic regulation of the reptile heart have reached equivocal conclusions. Indeed, unlike fish, amphibians, and mammals, it has been suggested the turtle heart lacks purinoceptors. Here, we study the effect of adenosine and ATP on isolated heart strips from three species of reptiles: the ...
Shimamoto Shinsaku S Department of Cardiology, Osaka Medical College, Osaka, - - 2014
Mechanical discoordination (MD) is known as a myocardial deformation of opposite strain during ejection, reflecting dyssynchronous electrical activation. We used speckle tracking echocardiography to examine the relationship between MD, left ventricular (LV) function and geometry, as well as electrical dyssynchrony in various nonischemic hearts. We examined 131 subjects (left bundle branch ...
Agarwal Anushree A Aurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke's Medical Centers, University of Wisconsin School of Medicine and Public Health, Milwaukee, - - 2014
Sarcoidosis is a multisystem, granulomatous disease of unknown etiology often seen in young adults, with cardiac involvement in more than one-quarter of sarcoid patients. The clinical presentation of cardiac sarcoid depends upon the location and extent of myocardium involved. Although cardiac sarcoid may produce asymmetrical septal hypertrophy, it is most ...
Linney C J CJ Department of Cardiology, Small Animal Teaching Hospital, School of Veterinary Science, University of Liverpool, Leahurst, Neston, CH64 - - 2014
To describe left atrial size, left atrial volume, left atrial function and left ventricular diastolic function in healthy cats and those with hypertrophic cardiomyopathy without and with congestive heart failure. A retrospective study of 61 client-owned, 21 healthy, 21 asymptomatic hypertrophic cardiomyopathy and 19 with hypertrophic cardiomyopathy and congestive heart ...
Ellims Andris H AH Heart Centre, Alfred Hospital, Melbourne, Victoria, Australia; Baker IDI Heart and Diabetes Research Institute, Melbourne, Victoria, - - 2014
The purpose of this study was to use cardiac magnetic resonance (CMR) imaging and invasive left ventricular (LV) pressure-volume (PV) measurements to explore the relationship between diffuse myocardial fibrosis and indexes of diastolic performance in a cohort of cardiac transplant recipients. The precise mechanism of LV diastolic dysfunction in the presence ...
Budhram Gavin R GR Tufts University School of Medicine, Department of Emergency Medicine, Baystate Medical Center, 759 Chestnut Street, Springfield, MA 01199. Electronic address: - - 2014
Intracardiac thrombus is a well-known complication of low-flow cardiac states including acute myocardial infarction and atrial fibrillation. Little is known, however, about the formation of intracardiac (left ventricular [LV]) thrombus during the extreme low-flow state of cardiac arrest. Using a swine model of sudden cardiac arrest, we examined the sonographic ...
Cobert Michael L ML Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, - - 2014
Machine perfusion of donor hearts is a promising strategy to increase the donor pool. Antegrade perfusion is effective but can lead to aortic valve incompetence and nonnutrient flow. Experience with retrograde coronary sinus perfusion of donor hearts has been limited. We tested the hypothesis that retrograde perfusion could support myocardial ...
Tanaka Yoshio Y Kanazawa University Graduate School of Medicine, Kanazawa, Ishikawa; Tsuruga Municipal Hospital, Tsuruga, Fukui, - - 2014
Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) attempts to improve the management of out-of-hospital cardiac arrest (OHCA) by laypersons who are unable to recognize cardiac arrest and are unfamiliar with CPR. Therefore, we investigated the sensitivity and specificity of our new DA-CPR protocol for achieving implementation of bystander CPR in OHCA victims not ...
Oguayo Kevin N KN Department of Internal Medicine, Baylor Scott & White Healthcare, Temple, Texas; College of Medicine, Texas A&M University Health Science Center, Temple, - - 2014
Flecainide is recommended as a first-line antiarrhythmic drug to maintain normal sinus rhythm in patients with atrial fibrillation (AF) who have structurally normal hearts or hypertension without left ventricular hypertrophy. Flecainide is a sodium channel blocker with minimal effects expected on ventricular repolarization. We describe the case of a 32-year-old ...
Huang Bingqing - - 2014
Mesenchymal stem cells (MSCs) have potential for the treatment of myocardial infarction. However, several meta-analyses revealed that the outcome of stem cell transplantation is dissatisfactory. A series of studies demonstrated that the combination of cell- and gene therapy was a promising strategy to enhance therapeutic efficiency. The aim of this ...
Li Zi-Lun - - 2014
Obesity associated with metabolic derangements (ObM) worsens the prognosis of patients with coronary artery stenosis (CAS), but the underlying cardiac pathophysiologic mechanisms remain elusive. We tested the hypothesis that ObM exacerbates cardiomyocyte loss distal to moderate CAS. Obesity-prone pigs were randomized to 4 groups (n=6 each): lean-sham, ObM-sham, lean-CAS, and ...
Maréchaux Sylvestre S Université Lille Nord de France/GCS-Groupement des Hôpitaux de l'Institut Catholique de Lille/Faculté Libre de Médecine, Cardiology Department, Université Catholique de Lille, Lille, France. Electronic address: - - 2014
Previous studies have demonstrated variable patterns of longitudinal septal deformation in patients with left ventricular (LV) dysfunction and left bundle branch block. This prospective single center study was designed to assess the relationship between septal deformation patterns obtained by two-dimensional speckle-tracking echocardiography and response to cardiac resynchronization therapy (CRT). One ...
Schober A A Department of Emergency Medicine, Medical University of Vienna - - 2014
Accidental hypothermic cardiac arrest is associated with unfortunate prognosis and large studies are rare. We therefore have performed an outcome analysis in patients that were admitted to Vienna University Hospital with the diagnosis of accidental hypothermic cardiac arrest. This study employed a retrospective outcome analysis of prospectively collected data in ...
Chalkias Athanasios A MSc "Cardiopulmonary Resuscitation", Medical School, National and Kapodistrian University of Athens, Athens, Greece; Hellenic Society of Cardiopulmonary Resuscitation, Athens, Greece. Electronic address: - - 2014
This review focuses on the presentation of the emerging technology of Metabolomics, a promising tool for the detection of identifying the unrevealed biological pathways that lead to cardiac arrest. Data sources: The electronic bases of PubMed, Scopus, and EMBASE were searched. Research terms were identified using the MESH database and ...
Metwally Amr Hany AH Mansoura University, Mansoura, Egypt. Electronic address: - - 2014
It is well known that chronic hepatitis C is associated with insulin resistance and metabolic syndrome which are risk factors for atherosclerosis and coronary heart disease. As a result, chronic hepatitis C might be thought, through its association with metabolic syndrome, to increase the risk of myocardial infarction. However, unexpectedly ...
Witayavanitkul Namthip N Loyola University Chicago, United - - 2014
Myocardial infarction (MI) is associated with depressed cardiac contractile function and progression to heart failure. Cardiac myosin binding protein-C (cMyBP-C), a cardiac-specific myofilament protein, is proteolyzed post-MI in humans, which results in an N-terminal fragment, C0-C1f. The presence of C0-C1f in cultured cardiomyocytes results in decreased Ca2+ transients and cell ...
Xu Zhihui - - 2014
Objective: Uncontrolled therapeutic gene expression and neovascularization in non-specific tissues has lowered the safety of gene therapy. The aim of the study was to identify a cardiac-specific promoter to control target gene expression in heart tissue in vitro and in vivo. Methods: Adenovirus vectors containing the firefly luciferase or hepatocyte ...
Tilton Richard K RK Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Temple University School of Medicine, Philadelphia, - - 2014
Pallister-Killian syndrome (PKS) is a sporadic multisystem genetic diagnosis characterized by facial dysmorphia, variable developmental delay and intellectual impairment, hypotonia, hearing loss, seizures, differences in skin pigmentation, temporal alopecia, diaphragmatic hernia, congenital heart defects, and other systemic abnormalities. Although congenital heart defects have been described in association with PKS, the ...
Chan W Y Wandy WY Cardiology Department, Christchurch Hospital, Christchurch, New - - 2014
We hypothesized that left atrial pressure (LAP) obtained by a permanent implantable sensor is sensitive to changes in cardiac resynchronization therapy (CRT) settings and could guide CRT optimization to improve the response rate. We investigated the effect of CRT optimization on LAP and its waveform parameters in ambulant heart failure ...
Clerico Aldo - - 2014
Abstract Although the perioperative event rate has declined over the past 30 years, as a consequence of the developments in anesthesiology and surgical techniques, perioperative cardiovascular complications are still a significant clinical problem. At the end of the last century, a pooled analysis of several large studies found a 30-day ...
De Ferrari Gaetano M GM Department of Cardiology, Fondazione IRCCS Policlinico San Matteo, Viale Golgi, 19, 27100, Pavia, Italy, - - 2014
Heart failure (HF) is accompanied by an autonomic imbalance that is almost always characterized by both increased sympathetic activity and withdrawal of vagal activity. Experimentally, vagal stimulation has been shown to exert profound antiarrhythmic activity and to improve cardiac function and survival in HF models. A open-label pilot clinical study ...
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