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Results 351 - 400 of 7327
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Arndt-H Kiessling K Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, - - 2014
Background: Myoglobin has become established as a serum marker of myocardial injury. However, myoglobin levels can increase exponentially without any correlation to postoperative clinical ischemia symptoms. In this retrospective study, we analyzed the associated factors for a non-ischemic myoglobin release.Methods: We performed a data analysis from 532 consecutive cardiac surgery ...
Ho Joanne M JM Sunnybrook Health Sciences Centre, G Wing 106, 2075 Bayview Ave, Toronto, Ontario M4N 3M5, Canada - - 2014
Venlafaxine is a commonly prescribed antidepressant, but whether its noradrenergic effects impart increased cardiovascular risk is unknown. We sought to examine the cardiac safety of venlafaxine relative to sertraline in older patients. We conducted a population-based retrospective cohort study using administrative health care databases in Ontario, Canada. We included all ...
Lynch Joseph P JP 3rd Division of Pulmonary, Critical Care Medicine, Allergy, and Clinical Immunology, David Geffen School of Medicine at UCLA, Los Angeles, - - 2014
Clinically evident sarcoidosis involving the heart has been noted in at least 2 to 7% of patients with sarcoidosis, but occult involvement is much higher (> 20%). Cardiac sarcoidosis is often not recognized antemortem, as sudden death may be the presenting feature. Cardiac involvement may occur at any point during ...
Wilson Mark M University of Illinois at Chicago, Chicago, IL, - - 2014
The main objective of this study is to investigate the effects of chronic and acute stress on blood pressure, heart rate variability and an indicator of cardiac contractility. The study also aims to describe the degree to which various demographic and lifestyle factors modify the observed effect. Chronic stress was ...
Shamim Shariq S 1 Cardiology Fellow University of Missouri, Kansas City, USA ; 2 Quality Improvement Director, Cardiology Section Truman Medical Center, USA ; 3 Professor and Chief of the Emergency Department University of Missouri, Kansas City and Truman Medical Center, USA ; 4 Formerly Associate Professor of Medicine University of Missouri, Kansas City and Chief of Cardiology of Truman Medical Center (Retired), - - 2014
Prompt reperfusion has been shown to improve outcomes in patients with acute ST-segment elevation myocardial infarction (STEMI) with a goal of culprit vessel patency in <90 minutes. This requires a coordinated approach between the emergency medical services (EMS), emergency department (ED) and interventional cardiology. The urgency of this process can ...
Zaman Maseeh Uz MU 1 Department of Radiology, The Aga Khan University Hospital (AKUH), Karachi, Pakistan ; 2 Department of Nuclear Cardiology, Karachi Institute of Heart Diseases (KIHD), Karachi, Pakistan ; 3 Department of Nuclear Medicine, Dr Ziauddin Medical University, Karachi, Pakistan ; 4 MBBS Students, Dow University of Health Sciences (DUHS), Karachi, - - 2014
The negative predictive value of a normal single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is very high. However, prognostic implication of a normal SPECT MPI in patients with known coronary artery disease (CAD) is not clear. Objective of this study was to evaluate the cardiac event rate in ...
Dear J J North Middlesex University Hospital, London, - - 2014
To report the rare case of a woman who was induced at term for deranged liver function, was later was recognised as secondary to cardiac dysfunction and a literature review of this rare condition. We reviewed the case notes and investigations of the above woman and collected the demographic details, ...
O'Dwyer Sl S Department of Obstetrics and Gynecology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa Whipps Cross University Hospital, Barts Health NHS Trust, London, - - 2014
To describe the aetiology and obstetric outcome in women presenting with pulmonary oedema during pregnancy and the puerperium. Retrospective case note analysis of 53 cases of pulmonary oedema causing significant respiratory distress and admission to intensive care at the Groote Schuur Hospital in Cape Town, South Africa. Cases could be ...
Spooner L L University Hospital Coventry Warwickshire, Coventry, - - 2014
All pregnant women are offered an anomaly scan including assessment of fetal cardiac anatomy. Congenital cardiac disease is a complex structural malformation of the heart and/or great arteries requiring surgical/catheter intervention within the first 6 months.(1) We reviewed the spectrum of defects diagnosed antenatally at our teaching hospital from 2011-2013 ...
Climov Daniela - - 2014
Biofeedback is a self-regulation therapy by which the patient learns how to optimize the functioning of his autonomic nervous system. It has been applied to patients with various cardiovascular disorders. The purpose of this study was to investigate the practical feasibility and the psychophysiological effects of biofeedback applied to heart ...
Husain Nazia - - 2014
Echocardiographic evaluation of systolic function in patients with single right ventricles (SRV) is important but remains challenging. Minimal data exist correlating echocardiographic indices with catheterization data in this population. The goal of this study was to evaluate which echocardiographic measurement correlated best with dP/dt (max) obtained by cardiac catheterization in ...
Rosenblatt Jeffrey J Maine Medical Center, Department of Cardiac Services, Tufts University School of Medicine, 22 Bramhall St, 119 Gannett Drive, Portland, ME, 04106, USA, - - 2014
Regadenoson is a selective A2A receptor agonist approved for use as a pharmacologic stress agent for myocardial perfusion imaging after several multicenter trials demonstrated its equivalence in diagnostic accuracy for the detection of coronary artery disease and a decreased incidence of serious side effects as compared to adenosine. Recently, the ...
Dellegrottaglie S S Division of Cardiology, Ospedale Medico-Chirurgico Accreditato Villa dei Fiori, C.so Italia, 157, 80011, Naples, Acerra, Italy, - - 2014
We report the case of a 32-year-old male with Chlamydia trachomatis infection and admitted with chest pain, signs of myocardial damage and coronary arteries free from significant atherosclerotic disease. Cardiac magnetic resonance imaging (MRI) documented imaging patterns of myocardial involvement suggestive of acute myocarditis, and repeated cardiac MRI examinations were ...
Lemkes Jorrit J Department of Cardiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, - - 2014
Patients with chest pain and a prehospital ST-segment elevation myocardial infarction (STEMI) are preferably treated with immediate percutaneous coronary intervention (PCI). However, patients with normalization of symptoms and ST-segment elevation upon hospital arrival (transient STEMI) received inconsistent therapy due to logistic reasons and the absence of evidence or explicit guidelines. ...
Chow Grant V GV Division of Cardiology, Johns Hopkins Medical Institutions, The Johns Hopkins University School of Medicine; Baltimore, - - 2014
Patients with acute MI, left bundle branch block (LBBB), and marked LV de-compensation suffer nearly 50% early mortality. Whether CRT improves hemodynamic status in this condition is unknown. We tested CRT in this setting, using a canine model of delayed lateral wall activation combined with 2-hours of coronary artery occlusion-reperfusion. ...
Benezet-Mazuecos Juan J Department of Cardiology, Hospital Universitario Fundación Jiménez Díaz-IDCsalud, Universidad Autónoma de Madrid, Madrid, - - 2014
Assessment of the prevalence of silent paroxysmal atrial fibrillation (AF) represents a challenge, since the arrhythmia may be brief, completely asymptomatic, and difficult to detect. Lack of symptoms from AF should not be equated to lack of risk of thromboembolic complications. Today's cardiac implantable electronic devices (CIED) diagnostics include system ...
Backhoff David D Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University, Robert-Koch-Str 40, 37075, Göttingen, - - 2014
Years and decades after the Mustard atrial switch repair for d-Transposition of the great arteries, there is a subset of patients at increased risk for sudden cardiac death due to ventricular tachyarrhythmias. To date, little is known about indications, efficacy and benefit of internal cardioverter defibrillator (ICD) therapy indication in ...
Genet Martin M - - 2014
Ventricular wall stress is believed to be responsible for many physical mechanisms taking place in the human heart, including ventricular remodeling, which is frequently associated with heart failure. Therefore, normalization of ventricular wall stress is the cornerstone of many existing and new treatments for heart failure. In this paper, we ...
Matsushita Kunihiro K From the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (K.M., Y.S., S.H.B., M.W., J.C.); Department of Medicine and Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison (B.C.A.); Department of Medicine, Section of Atherosclerosis and Vascular Medicine, Baylor College of Medicine, and the Methodist DeBakey Heart and Vascular Center, Houston, TX (R.C.H., C.M.B.); Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.D.S.). - - 2014
Traditional predictors suboptimally predict cardiovascular disease (CVD) in individuals with chronic kidney disease (CKD). This study compared 5 nontraditional cardiac and kidney markers on the improvement of cardiovascular prediction among those with CKD. Among 8622 participants aged 52 to 75 years in the Atherosclerosis Risk in Communities (ARIC) Study, cardiac ...
Esper Stephen A SA UPMC, Pittsburgh, PA, - - 2014
The techniques and equipment of cardiopulmonary bypass (CPB) have evolved over the past 60 years, and numerous numbers of cardiac surgical procedures are conducted around the world using CPB. Despite more widespread applications of percutaneous coronary and valvular interventions, the need for cardiac surgery using CPB remains the standard approach ...
Senanayake Eshan L EL Department of Cardiac Surgery, University Hospital Birmingham NHS Foundation Trust, Birmingham, - - 2014
Coronary artery disease in the donor heart is an established cause of early graft failure. However, identification of this before implantation is difficult. Cardiogenic shock associated with significant myocardial infarction during the early postoperative period is rare. Here, we report a case of a 42-year-old man who presented acutely with ...
Martindale Jennifer L JL Emergency Department, State University of New York Downstate, Kings County Hospital, Brooklyn, New - - 2014
To many physicians, hyperkalemia is the first diagnosis ascribed to any patient with end-stage renal disease and abnormal electrocardiographic morphologies or dysrhythmias. A 52-year-old man with end-stage renal disease presented in cardiac arrest. The patient was initially presumed to have hyperkalemia, based on the appearance of wide QRS complexes on ...
Hari Pawan P Division of Cardiology, Loma Linda University Medical Center, Loma Linda, - - 2014
Patent foramen ovale (PFO) is a common variant present in up to 25% of the population. Atrial septal defect (ASD) is a direct communication between the 2 atrial chambers, of which the ostium secundum variety is the most common. This manuscript is an in depth review of the complex atrial ...
Blei Francine F Vascular Birthmark Institute, St. Luke's Roosevelt Hospital, New York, New - - 2014
There is no uniform pretreatment cardiac evaluation for infants treated with oral propranolol, which is now the drug of choice for hemangiomas of infancy requiring systemic medical intervention. The aim of this study was to report and evaluate the findings of pretreatment cardiac evaluation. Data were reviewed for patients evaluated ...
Lin Kai K Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States. Electronic address: - - 2014
To test the hypothesis that biomechanical changes are quantitatively related to morphological features of coronary arteries in heart transplant (HTx) recipients. With IRB approval, three-dimensional (3D) magnetic resonance (MR) angiography and two-dimensional (2D) black-blood stead-state free precession (SSFP) MR imaging were performed to image coronary arteries of 36 HTx patients. ...
Kalogeropoulos Andreas P AP Division of Cardiology, Emory University, Atlanta, GA. Electronic address: - - 2014
Inotropes are widely used in hospitalized systolic heart failure (HF) patients, especially those with low systolic blood pressure (SBP) or cardiac index. Also inotropes are considered harmful in nonischemic HF. We examined the association of in-hospital inotrope use with (1) major events (death, ventricular assist device, or heart transplant) and ...
Lynch Thomas L TL Department of Cell and Molecular Physiology, Division of Cardiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, 60153, - - 2014
Cardiac myosin binding protein-C (cMyBP-C) is a regulatory protein of the contractile apparatus within the cardiac sarcomere. Ischemic injury to the heart during myocardial infarction (MI) results in the cleavage of cMyBP-C in a phosphorylation-dependent manner and release of an N-terminal fragment (C0C1f) into the circulation. C0C1f has been shown ...
Huang Lixing L State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen 361005, - - 2014
Growing evidence indicates that polycyclic aromatic hydrocarbons (PAHs) can lead to cardiac hypertrophy and recent research indicates that exposure to low dose crude oil during early embryonic development may lead to impacts on heart health at later life stages. The aim of this study was to evaluate whether exposure during ...
Dhein Stefan S Klinik für Herzchirurgie, Universität Leipzig, Herzzentrum, Struempellstr. 39, 04289, Leipzig, Germany, - - 2014
Mechanical stretch has been shown to provoke arrhythmia. We wanted to analyze ventricular arrhythmia induced by local left ventricular stretch in order to find out, where arrhythmias originate and whether they can be prevented pharmacologically. Isolated rabbit hearts (Langendorff technique) were submitted to increased left ventricular stretch at the left ...
Anderson Robert H RH Institute of Genetic Medicine, Newcastle University, Newcastle, United - - 2014
The past decades have seen immense progress in the understanding of cardiac development. Appreciation of precise details of cardiac anatomy, however, has yet to be fully translated into the more general understanding of the changing structure of the developing heart, particularly with regard to formation of the septal structures. In ...
Pfob Michael M CardioVital Institute of Preventive and Rehabilitation Medicine, Grieskirchnerstraße 49, 4600, Wels, Austria, - - 2014
In patients with coronary heart disease, both arterial stiffness and wave reflections are increased and predict unfavorable cardiovascular events. Cardiac rehabilitation has the goal to reduce risk factors and slow the progression of the disease. The aim of this study was to prospectively determine the impact of an ambulatory cardiac ...
Danese Elisa E Laboratory of Clinical Chemistry and Hematology, University of Verona , Verona , - - 2014
Atrial fibrillation (AF) is the most common among the severe cardiac arrhythmias and carries a significant risk of mortality and morbidity in the general population. The most important complication is represented by development of one or more thrombi in the left atrium of the dyskinetic heart, and their successive cerebral ...
Aminzadeh Mohammad A MA Cedars-Sinai Heart Institute, 8700 Beverly Boulevard, Los Angeles, CA 90048, - - 2014
Cardiosphere-derived cells (CDCs) produce regenerative effects in the post-infarct setting. However, it is unclear whether CDCs are beneficial in non-ischaemic dilated cardiomyopathy (DCM). We tested the effects of CDC transplantation in mice with cardiac-specific Gαq overexpression, which predictably develop progressive cardiac dilation and failure, with accelerated mortality. Wild-type mouse CDCs ...
Liu Xinbing X aDepartment of Cardiology, Shanghai Shi Dong Hospital bDepartment of Geriatrics, Shanghai No. 3 People's Hospital cDepartment of Cardiology, An Tu Hospital, Shanghai, - - 2014
The aim of this study was to investigate the effects of a noninvasive positive pressure ventilation therapy on cardiac structure and function in patients with coronary heart disease combined with obstructive sleep apnea/hypopnea syndrome (OSAHS). Eighty patients with coronary heart disease OSAHS were divided randomly into treatment (n=40) and control ...
van Riet Evelien E S EE Julius Center for Health Sciences and Primary care, University Medical Center Utrecht, PO Box 85500, 3508 AB, Utrecht, the - - 2014
The majority of patients with heart failure are diagnosed in primary care, but underdiagnosis is common. Shortness of breath is a prevalent complaint of older persons and one of the key symptoms of heart failure. We assessed the prevalence of unrecognized heart failure in elderly patients presenting to primary care ...
Cetin Metin M Clinic of Cardiology, Çerkezköy State Hospital; Tekirdağ-Turkey. - - 2014
Vitamin D status has been implicated in the pathophysiology of heart failure (HF). The aim of this study was to investigate the association between vitamin D levels with heart rate variability and heart rate turbulence in patients with heart failure whom had ischemic and non-ischemic dilated cardiomyopathy. Study designed as ...
de Vette Liesbeth C LC Liesbeth C de Vette, Jasper J Brugts, Jacky S McGhie, Jolien W Roos-Hesselink, Department of Cardiology, Erasmus MC, 230 3015 CE Rotterdam, The - - 2014
M Ebstein is usually diagnosed in early childhood or adolescence. The young woman in our case complainted of fatigue and shortness of breath, on physical examination she showed signs of heart failure with raised central venous pressure, palpable liver, an a cardiac murmer. Based on these findings she should have ...
Penna Claudia C Dipartimento di Scienze Cliniche e, Biologiche Università di Torino, Ospedale S. Luigi, Regione Gonzole, 10, 10043, Orbassano, TO, - - 2014
Melusin is a muscle-specific protein which interacts with β1 integrin cytoplasmic domain and acts as chaperone protein. Its overexpression induces improved resistance to cardiac overload delaying left ventricle dilation and reducing the occurrence of heart failure. Here, we investigated possible protective effect of melusin overexpression against acute ischemia/reperfusion (I/R) injury ...
Mei Zhusong Z Key laboratory of stress medicine, Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Haidian District, Beijing, China, - - 2014
Myocardial hypertrophy is an adaptive response of the heart to work overload. Pathological cardiac hypertrophy is usually associated with the ultimate development of cardiac dysfunction and heart failure. The mitochondria have an important function in the development of cardiac hypertrophy. However, mitochondrial adaptations to hypertrophic stimulus remain ambiguous. A rat ...
Kodama Ken K Department of Thoracic Surgery, Yao Municipal Hospital, 1-3-1 Ryuge-cho, Yao, Osaka, 581-0069, Japan, - - 2014
We experienced an excision of the mediastinal tumor located in left anterior mediastinum found in a 21-year-old woman. The histologic diagnosis of Hodgkin's lymphoma was obtained. After operation, she was treated with mantle field radiotherapy (total 42 Gy) followed by chemotherapy. At 43-year old, she developed constrictive pericarditis and heart failure ...
Christensen Thomas Emil TE Department of Clinical Physiology, Nuclear Medicine & PET, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen E, Denmark, - - 2014
In patients with heart failure (HF) due to coronary disease, a combined evaluation of perfusion and glucose metabolism by cardiac single photon emission computed tomography (SPECT)/positron emission tomography (PET) can be used to distinguish viable from non-viable myocardium, and current guidelines recommend cardiac SPECT and fluorodeoxyglucose (FDG) PET for viability ...
Kalam Kashif K Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, - - 2014
Global longitudinal strain (GLS) is a robust, well validated and reproducible technique for the measurement of LV longitudinal deformation. We sought to assemble evidence that GLS is an accurate marker in predicting cardiovascular outcomes, compared to LVEF. We undertook a systematic review of the evidence from observational studies which compared ...
Mitsuyama Hirofumi H Hokkaido University Graduate School of - - 2014
Background: Action potential duration alternans (APD-ALT), defined as long-short-long repetitive pattern of APD, potentially leads to lethal ventricular arrhythmia. However, the mechanisms of APD-ALT in the arrhythmogenesis of cardiac hypertrophy remain undetermined. Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is known to modulate the function of cardiac sarcoplasmic reticulum and play an ...
Böhm Michael M Universitätsklinikum des Saarlandes, Homburg/Saar, - - 2014
Higher heart rate is associated with poorer outcomes in patients with heart failure and reduced ejection fraction (HF-REF). Less is known about the association between heart rate and outcomes in patients with heart failure and preserved ejection fraction (HF-PEF). Therefore, we examined the relationship between heart rate and outcomes in ...
Mittal Suneet S Arrhythmia Institute, Valley Health System, Columbia University College of Physicians and Surgeons, New York, NY, Ridgewood, - - 2014
This study determined whether the presence of non-sustained ventricular tachycardia (NSVT) was predictive of clinical events in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy) patients treated with cardiac resynchronization therapy-defibrillator (CRT-D). We analyzed 24-hour Holters for the presence of NSVT. Patients were then stratified by the etiology (ischemic or ...
Holmberg Fredrik Eo - - 2014
Abstract Objectives:The objective was to investigate potential protective effects of two conditioning methods, on myocardial ischemic- and reperfusion injury in relation to cardiac surgery. Design:68 patients were randomly assigned to either a control group (n=23), a remote ischemic preconditioning group (n=23) or a glucagon-like peptide 1 analogue group (n=22). The ...
Maurin O O Brigade des sapeurs-pompiers de Paris, 1 place Jules-Renard, 75017 - - 2014
Intraosseous infusion is increasingly used as an alternative to intravenous infusion. It is recommended for the cardiac arrest of a child in the first instance and after two failed attempts of intravenous infusion in the cardiac arrest of adults. Its rapid use and its low failure rate justify its use ...
Nagai Toshiyuki - - 2014
Cardiac death is the leading cause of mortality associated with sarcoidosis in Japan. However, the involvement of sarcoidosis infiltration often remains undetected. Recently, late gadolinium enhancement with cardiovascular magnetic resonance (LGE-CMR) imaging has been introduced for the detection of myocardial infiltrative disease, as it enables the detection of even minor ...
Carmo Lucas S LS Department of Pathology, Ribeirão Preto Medical School, University of São Paulo, - - 2014
We report an autopsy case of a 24-year-old man with diagnoses of advanced alcoholic liver cirrhosis, portal hypertension, and esophageal variceal bleeding that presented extensive myocardial infarction after treatment with terlipressin. On postmortem examination the cut surface of the heart presented myocardial infarction implicating the left ventricle free wall, apex ...
Fumagalli Francesca F IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milan, - - 2014
During ischemia, enhancement of the "late Na(+) current" (INaL) contributes to intracellular Ca(2+) overload. Dysregulation of intracellular Ca(2+) homeostasis plays a critical role in the pathophysiology of cardiac arrest and cardiopulmonary resuscitation (CPR), leading to ventricular arrhythmias and left ventricle (LV) dysfunction. We investigated the effects of the INaL blocker ...
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