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Results 301 - 350 of 6406
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Bernard-Brunet Anne - - 2014
Restoration of the mechanical and endocrine functions of the left atrium remains controversial after electrical cardioversion treatment for persistent atrial fibrillation. The objective of the prospective study was to describe the recovery of the endocrine and mechanical functions of the left atrium. Evaluation of left atrium recovery after electrical cardioversion ...
Min Gu G Cardiovascular Medicine, Jiangsu Subei People's Hospital, - - 2014
The aims of this study were to compare ventricular repolarisation parameters in patients who underwent cardiac resynchronisation therapy (CRT) at Sun Yat-sen University Memorial Hospital under different ventricular pacing modes and to understand effects of epicardial pacing on ventricular repolarisation. The study included 55 patients who underwent CRT. During follow-up ...
Lujan Heidi L HL Wayne State University School of - - 2014
Cardiac electro-physiologic dysfunction is a major cause of death in humans. Accordingly, electrophysiological testing is routinely performed in intact, conscious, humans to evaluate arrhythmias and disorders of cardiac conduction. However, to date, in vivo electrophysiological studies in mice are limited to anesthetized, open chest or closed chest preparations. However cardiac ...
Quarta Candida Cristina CC Brigham and Women's Hospital, Harvard Medical School, Boston, MA & University of Bologna and S.Orsola-Malpighi Hospital, Bologna, - - 2014
Immunoglobulin light chain (AL)-related cardiac amyloidosis (CA) has a worse prognosis than either wild type (ATTRwt) or mutant (ATTRm) transthyretin (TTR) CA. Detailed echocardiographic studies have been performed in AL, but not in TTR amyloidosis, and might give insight into this difference. We assessed cardiac structure and function and outcome ...
Ballestri Stefano S Stefano Ballestri, Division of Internal Medicine, Pavullo Hospital, 41026 Pavullo, - - 2014
Non-alcoholic fatty liver disease (NAFLD) has emerged as a public health problem of epidemic proportions worldwide. Accumulating clinical and epidemiological evidence indicates that NAFLD is not only associated with liver-related morbidity and mortality but also with an increased risk of coronary heart disease (CHD), abnormalities of cardiac function and structure ...
Patel Chetan B CB Division of Cardiology, Duke University Medical Center, Durham, North Carolina. Electronic address: - - 2014
Mechanical circulatory support has seen numerous advances in the recent years, with important observations made to guide patient selection for the therapy, indications for use, and management of devices after implantation. There is rapid growth in the use of left ventricular assist device therapy (LVAD) for advanced heart failure, with ...
Solanki Pallavi P Division of Cardiology, Rutgers-New Jersey Medical School, 185 S. Orange Avenue, Newark, NJ, 07103, USA, - - 2014
Heart failure is the leading cause of hospitalization in the USA. Despite major advances in the medical and device-related therapy including chronic resynchronization therapy for management of heart failure, significant number of patients eventually require advanced cardiac therapy including mechanical circulatory support or heart transplant. Heart transplant is a gold ...
Zhang Yuan Y Peking Union Medical College, Chinese Academy of Medical Science, Biochemistry and Molecular Biology, Beijing, Beijing, China ; - - 2014
Aim: Mitofilin was originally described as a heart muscle protein (HMP) because of its abundance in heart tissue, however its function in the heart is still to be elucidated. Thus this study aims to investigate the role of mitofilin in the heart in response to hypertrophic stimuli. Results: In this ...
Gong Yibo - - 2014
Primary cardiac tumor in infancy is an uncommon condition which is rarely accompanied with congenital heart disease. Although these tumors are generally benign, the complication associated with it, such as arrhythmia, outflow tract obstruction, and heart failure, may result in early mortality, when combined with congenital heart disease. Early surgical ...
Sansone Fabrizio F From the Division of Cardiac Surgery, "Ospedali Riuniti Papardo-Piemonte" Hospital, Messina, - - 2014
Cases of left ventricular pseudoaneurysm caused by patch leakage after left ventricular remodeling are quite rare. We describe the case of a 66-year-old man operated on through a left thoracotomy using the Port Access platform to treat patch detachment after left ventricular remodeling.
McGarvey Jeremy R JR From the Gorman Cardiovascular Research Group, Division of Cardiac Surgery, University of Pennsylvania Health System, Philadelphia, PA - - 2014
Despite advances in design, modern ventricular assist device placement involves median sternotomy and cardiopulmonary bypass and is associated with infectious/embolic complications. In this study, we examine the feasibility and function of a novel minimally invasive, non-blood-contacting epicardial assist device in a porcine ischemic cardiomyopathy model. Feasibility was first tested in ...
Qazi Taimoor H TH Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstr. 6, 91058 Erlangen, - - 2014
Cardiovascular diseases (CVD's), especially myocardial infarction (MI), are the leading cause of morbidity and mortality in the world also resulting in huge economic burden on national economies. A cardiac patch strategy aims at regenerating an infarcted heart by providing healthy functional cells to the injured region via a carrier substrate, ...
Russo Valerio V Department of Chemical Engineering, Queen's University, 19 Division Street, Kingston, Ontario, Canada K7L 3N6; Human Mobility Research Centre, Kingston General Hospital, 76 Stuart Street, Kingston, Ontario, Canada K7L - - 2014
Myocardial infarction (MI) is one of the leading causes of mortality worldwide and is associated with irreversible cardiomyocyte death and pathological remodeling of cardiac tissue. In the past 15 years, several animal models have been developed for pre-clinical testing to assess the potential of stem cells for functional tissue regeneration ...
Haynes Premi P Department of Physiology, University of Kentucky, Lexington, KY; Center for Muscle Biology, University of Kentucky, Lexington, - - 2014
Heart failure is associated with pump dysfunction and remodeling but it is not yet known if the condition affects different transmural regions of the heart in the same way. We tested the hypotheses that the left ventricles of non-failing human hearts exhibit transmural heterogeneity of cellular level contractile properties, and ...
Fattouch Khalil K Department of Cardiovascular Surgery, GVM Care and Research, Maria Eleonora Hospital, Palermo, Italy. Electronic address: - - 2014
The surgical approach for ischemic mitral regurgitation remains unclear. Many studies are in favor of adding the subvalvular procedure to mitral annuloplasty to reduce recurrent mitral regurgitation. This study reports the clinical and echocardiographic outcomes of papillary muscle relocation combined with mitral annuloplasty. From 2003, 115 patients with severe ischemic ...
Mannacio Vito V Department of Cardiac Surgery, University of Naples Federico II, Naples, Italy. Electronic address: - - 2014
A history of percutaneous coronary intervention increases the risk of death and complications of coronary artery bypass grafting. This retrospective multicenter study evaluated the impact of continuative use of statin on postoperative outcomes when subsequent elective coronary artery bypass grafting is required after percutaneous coronary intervention. Among 14,575 patients who ...
Su Guanhua G Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, - - 2014
How to identify the early signs of hypertensive heart disease is the key to block or reverse the process of heart failure. The aim of this study was to evaluate the predictive value of left atrial (LA) enlargement in the early stage of hypertensive heart disease and to explore the ...
Shapiro Scott D SD Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY 10029, - - 2014
Cyclin A2 (Ccna2), normally silenced after birth in the mammalian heart, can induce cardiac repair in small-animal models of myocardial infarction. We report that delivery of the Ccna2 gene to infarcted porcine hearts invokes a regenerative response. We used a catheter-based approach to occlude the left anterior descending artery in ...
Ogano Michio M Department of Cardiovascular Medicine, Shizuoka Medical Center, 762-1 Nagasawa, Shimizu, Sunto Shizuoka 4110906, Japan. Electronic address: - - 2014
Left bundle branch block (LBBB) causes intraventricular conductional delay resulting in left ventricle (LV) mechanical dyssynchrony. In the absence of coronary artery disease, patients with LBBB often have diminished accumulation of technetium-99m compounds at the myocardial septal area in electrocardiogram-gated single-photon emission computed tomography (SPECT). We investigated whether cardiac resynchronization ...
Scholz Eberhard P EP Department of Internal Medicine III, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany. Electronic address: - - 2014
The discrimination of atrial flutter (AFlu) and atrial fibrillation (AFib) can be made difficult by an irregular ventricular response due to complex conduction phenomena within the atrioventricular (AV) node, known as multilevel AV block. We tested the hypothesis that a mathematical algorithm might be suitable to discriminate between both arrhythmia. ...
Nhan Nguyen Huu NH Medical and Health Science Center, University of Debrecen, - - 2014
A 42-year-old man sustained blunt thoracic trauma after a motor vehicle accident. He underwent an urgent operation. Operative findings included a large hematoma, a 4-cm tear in the left atrial appendage, and a long pleuropericardial rupture along the right phrenic nerve. We repaired the left atrial appendage without cardiopulmonary bypass, ...
Vollmer Thomas - - 2014
Abstract In the project "Individualized Biomonitoring in Heart Failure (Biomon-HF)," innovative sensors and algorithms for measuring vital signs, i.e., during the nocturnal sleep period, have been developed and successfully tested in five clinical feasibility studies involving 115 patients. The Biomon-HF sensor concepts are an important step toward future patient-customized telemonitoring ...
van Spreeuwel A C C AC Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. - - 2014
In the cardiac microenvironment, cardiomyocytes (CMs) are embedded in an aligned and structured extracellular matrix (ECM) to maintain the coordinated contractile function of the heart. The cardiac fibroblast (cFB) is the main cell type responsible for producing and remodeling this matrix. In cardiac diseases, however, adverse remodeling and CM death ...
Wang W W Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, - - 2014
Hospital and home-based cardiac rehabilitation programmes improve the health outcomes of cardiac patients. Both types of programmes include patient education as a core component. However, many patients do not attend cardiac rehabilitation programmes for a variety of reasons. In Singapore, where cardiac rehabilitation is comparatively uncommon, patient education is usually ...
Guhathakurta Soma S Department of Engineering Design, Indian Institute of Technology Madras, Chennai, - - 2014
This study aimed to create a myocardial tissue construct by tissue engineering to repair, replace, and regenerate damaged cardiac tissue. Human cardiac muscles harvested from a homograft heart retrieval system were decellularized followed by coating with electrospun nanofibers to make them amenable to scaffolding. These processed cardiac tissues were nourished ...
Troalen Thomas - - 2014
Assessment of cyclic myocardial blood flow (MBF) variations can be an interesting addition to the characterization of microvascular function and its alterations. To date, totally non-invasive in vivo methods with this capability are still lacking. As an original technique, a cine arterial spin labeling (ASL) cardiovascular magnetic resonance approach is ...
Parsonage William A WA Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia. - - 2014
To validate an accelerated biomarker strategy using a high-sensitivity cardiac troponin T (hs-cTnT) assay for diagnosing acute myocardial infarction (AMI) in patients presenting to the emergency department with chest pain; and to validate this strategy in combination with the National Heart Foundation of Australia/Cardiac Society of Australia and New Zealand ...
Hassani K K 1Department of Biomechanics, Tehran Science and Research Branch, Islamic Azad University, Tehran, - - 2014
Phonocardiography, the digital recording of heart sounds, is becoming increasingly popular as a primary detection system for diagnosing heart disorders and is relatively inexpensive. The electrocardiogram (ECG) is often used when recording the phonocardiogram in order to help identify the systolic and diastolic components. In this study, a heart sound ...
West Christopher R CR University of British Columbia, - - 2014
Background: SCI causes altered autonomic control and severe physical deconditioning that converge to drive maladaptive cardiac remodeling. Aims: We used a clinically relevant experimental model to investigate the cardio-metabolic responses to spinal cord injury (SCI) and to establish whether passive hind-limb cycling elicits a cardio-protective effect. Methods: Initially, 21 male ...
Dunlay Shannon M SM Division of Cardiovascular Diseases and Mayo Clinic, Rochester, Minnesota; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota. Electronic address: - - 2014
Participation in cardiac rehabilitation has been shown to decardiac rehabilitationease mortality following acute myocardial infarction, but its impact on readmissions requires examination. We conducted a population-based surveillance study of residents discharged from the hospital following their first-ever myocardial infarction in Olmsted County, Minnesota from January 1, 1987 to September 30, ...
Buyandelger Byambajav B Imperial College, British Heart Foundation-Centre for Research Excellence, National Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Hammersmith Campus, Du Cane Road, London, W12 0NN, - - 2014
Mechanosensation and mechanotransduction are fundamental aspects of biology, but the link between physical stimuli and biological responses remains not well understood. The perception of mechanical stimuli, their conversion into biochemical signals, and the transmission of these signals are particularly important for dynamic organs such as the heart. Various concepts have ...
Mizusawa Yuka Y AMC Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The - - 2014
Early repolarization (ER) has been accepted as a benign ECG variant for decades. Two seminal studies challenged this notion and have demonstrated that ER pattern is associated with an increased risk of arrhythmic and cardiac mortality in patients with idiopathic ventricular fibrillation (IVF) and in the general population. Recent clinical ...
Mohmand-Borkowski Adam A Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J3-4, Cleveland, OH, 44195, - - 2014
While atrial fibrillation is common comorbidity in patients with cardiomyopathy and heart failure, diagnosis and management often focuses on tackling rate and rhythm control rather than elucidating pathogenic mechanisms related to underlying myocardial substrates. This review summarizes our current understanding of the natural history of cardiomyopathies presenting with atrial fibrillation, ...
Mori Makoto M Division of Cardiology, Emory University School of Medicine, 1365 Clifton Road, NE, Bldg A - Suite 2447, Atlanta, GA, 30322, - - 2014
The role of ventricular dysfunction in late morbidity and mortality of univentricular hearts has been described previously. However, a significant proportion of adult Fontan patients who die or require heart transplantation do so with preserved ventricular function. The clinical deterioration in patients who have undergone Fontan palliation requires a broader ...
Senaidi Khalfan Al KA Division of Pediatric Cardiology, Sultan Qaboos University, Sultanate of - - 2014
The postnatal survival of patients with congenital cardiac defects such as hypoplastic left heart syndrome (HLHS) is dependent on the patency of the ductus arteriosus and the presence of an unrestrictive atrial septal defect (ASD). We report a six week old infant with HLHS and tricuspid valve regurgitation with restrictive ...
Grivas Jamie J DePauw University, Department of Biology, Greencastle, IN, - - 2014
The remarkable ability of the heart to regenerate has been demonstrated in the zebrafish and giant danio, two fish members of the cyprinid family. Here we use light and electron microscopy to examine the repair response in the heart of another cyprinid, the goldfish (Carassius auretus), following cautery injury to ...
Oki Masami M Department of Emergency and Critical Care Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.. Electronic address: - - 2014
Sepsis is a cluster of heterogeneous syndromes associated with progressive endotoxaemic developments, ultimately leading to damage of multiple organs, including heart. However, the pathogenesis of sepsis-induced myocardial dysfunction is still not fully understood. The present study is the first to examine alterations in expression of key angiogenic signaling system mediated ...
Işcen Sinan S Department of Cardiology, Diyarbakir Military Hospital, Yenişehir/Diyarbakir, Diyarbakir, - - 2014
Effects of nonright-handedness on risk for sudden death associated with coronary artery disease via sympathetic imbalance contributed to ventricular arrhythmogenesis previously have been demonstrated. This study hypothesized that left-handedness might be associated with cardiac autonomic functions in healthy young men. The aim of this study was to examine the association ...
Wybraniec Maciej Tomasz MT Medical University of Silesia Upper Silesian Medical Center Public Hospital No 7 in Katowice. - - 2014
The purpose of this review was to summarize the up-to-date knowledge on clinical presentation and management of neurocardiogenic injury and to deliver the evidence of common pathophysiology of this broad spectrum of disorders. Medline and EmBase database were searched to obtain original research articles and review papers using following key ...
Lazarescu Cristina C Department of Anesthesia and Intensive Care, General Hospital of Metz, Metz, France. Electronic address: - - 2014
The aim of this study was to prospectively reassess the natural evolution and complications of temporary epicardial wires (TEW) after cardiac surgery. Observational prospective study. Monocentric. All adult patients having cardiac surgery with TEW insertion, except for those undergoing cardiac transplantation or having permanent pacemakers. Thresholds were measured daily until ...
Corban Michel T MT Andreas Gruentzig Cardiovascular Center, Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, - - 2014
Patients with myocardial bridges are often asymptomatic but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope or even sudden cardiac death. This review presents our understanding of the pathophysiology of myocardial bridging and describes prevailing diagnostic modalities and therapeutic options for this challenging clinical ...
Chow B B Animal Health Center, College of Veterinary Medicine, Mississippi State University, P.O. Box 6100, Starkville, MS, 39762-6100, - - 2014
A six-year-old female spayed mixed-breed dog was referred following a 3-week history of lameness and progressive neurological deficits in both hindlimbs, and a 1-week history of a cardiac arrhythmia. The dog was diagnosed with hypothyroidism, atrial fibrillation, myocardial dysfunction and arterial thromboembolism. Cardioversion occurred after 2 weeks of levothyroxine supplementation, with ...
Bartels Karsten - - 2014
Purpose of the review. This review aims to summarize recent findings relevant for perioperative 2- and 3-dimensional imaging of the right heart with transesophageal echocardiography. Special attention is given to developments that are likely to affect future approaches for prevention and therapy of perioperative right heart failure. Recent findings. Three-dimensional ...
Cai Qi-Zhe QZ Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong; - - 2014
Little is known regarding the natural longitudinal changes in cardiac structure and function in CKD. We hypothesized that baseline CKD stage is associated with progressive worsening in cardiac structure and function. We conducted a prospective longitudinal study, recruiting 300 patients with stages 3-5 CKD from a major regional tertiary center ...
Ma Yonggang Y San Antonio Cardiovascular Proteomics Center, San Antonio, TX, - - 2014
The cardiac extracellular matrix (ECM) fills the space between cells, supports tissue organization, and transduces mechanical, chemical, and biological signals to regulate homeostasis of the left ventricle (LV). Following myocardial infarction (MI), a multitude of ECM proteins are synthesized to replace myocyte loss and form a reparative scar. Activated fibroblasts ...
Smetkin A A AA Department of Anaesthesiology and Intensive Care Medicine, Northern State Medical University, Arkhangelsk, Russian - - 2014
/st>Cardiac output monitoring, as a part of a goal-directed haemodynamic management, has been shown to improve perioperative outcome in high-risk patients undergoing major surgical interventions. However, thorough validation of cardiac output monitoring devices in different clinical conditions is warranted. The aim of our study was to compare the reliability of ...
Chen Youwen Y Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, - - 2014
A 25-year old woman with complicated cyanotic heart disease and a large persistent left superior vena cava (PLSVC) with dysplasia of the innominate vein draining into the left atrium underwent cardiac surgery. Six months later, the narrowed PLSVC was successfully occluded using a muscular ventricular septal occluder (nitinol wire mesh). ...
Ferrer María F MF Instituto de Biotecnología y Biología Molecular, Universidad Nacional de La Plata, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), - - 2014
SUMMARY Chagas heart disease is a major public concern since 30% of infected patients develop cardiac alterations. The relationship between Trypanosoma cruzi discrete typing units (DTUs) and the biological properties exhibited by the parasite population has yet to be elucidated. In this study, we analysed the expression of α-smooth muscle ...
Hamid Tahir T Royal Blackburn Hospital NHS Trust, , Blackburn, - - 2014
Traditionally, patients are kept nil-per-os/nil-by-mouth (NPO/NBM) prior to invasive cardiac procedures, yet there exists neither evidence nor clear guidance about the benefits of this practice. To demonstrate that percutaneous cardiac catheterisation does not require prior fasting. The data source is a retrospective analysis of data registry of consecutive patients who ...
Fouzas Sotirios S Neonatal Intensive Care Unit, University Hospital of Patras, University of Patras Medical School, Patras, - - 2014
Background:The early postnatal cardiovascular consequences of intrauterine growth restriction (IUGR) have not been completely elucidated. This study aimed to evaluate the effect of IUGR on neonatal myocardial function and cardiovascular adaptation to extrauterine life.Methods:Conventional and tissue-Doppler echocardiographic parameters, were compared on the second and fifth postnatal day between 30 IUGR ...
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