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Marunouchi Tetsuro T Department of Molecular and Cellular Pharmacology, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, - - 2014
The mechanisms underlying mitochondrial impairment in the failing heart are not yet clear. In a previous study, we found that the levels of small heat shock proteins (HSP) such as mitochondrial HSPB1 and HSPB8 in the failing heart following myocardial infarction were decreased. In the present study, to verify the ...
Schuetze Katherine B KB Department of Medicine, Division of Cardiology, University of Colorado Denver, 12700 E. 19th Ave., Aurora, Colorado - - 2014
Cardiac fibrosis is implicated in numerous physiologic and pathologic conditions, including scar formation, heart failure and cardiac arrhythmias. However the specific cells and signaling pathways mediating this process are poorly understood. Lysine acetylation of nucleosomal histone tails is an important mechanism for the regulation of gene expression. Additionally, proteomic studies ...
Yu Yang Y Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, Guangdong Province, People's Republic of - - 2014
Cardiac fibrosis is involved in a lot of cardiovascular pathological processes. Cardiac fibrosis can block conduction, cause hypoxia, strengthen myocardial stiffness, create electrical heterogeneity, and hamper systolic ejection, which is associated with the development of arrhythmia, heart failure and sudden cardiac death. Besides the initial stimulating factors, the cardiac fibroblasts ...
Sung Kuo-Tzu - - 2014
Solitary papillary muscle (PM) hypertrophy is an unique type of hypertrophic cardiomyopathy (HCM), which is characterized by predominant papillary muscle hypertrophy sparing the rest of other left ventricular segments. It has recently drawn our attention about the mechanism of left ventricular mid-cavity obstruction and the influence of pressure gradient in ...
Paul David S DS Department of Nutrition, University of NC at Chapel Hill, 27599, USA. Electronic address: - - 2014
In mice with temporally-induced cardiac-specific deficiency of acyl-CoA synthetase-1 (Acsl1(H-/-)), the heart is unable to oxidize long-chain fatty acids and relies primarily on glucose for energy. These metabolic changes result in the development of both a spontaneous cardiac hypertrophy and increased phosphorylated S6 kinase (S6K), a substrate of the mechanistic ...
Deb Arjun A Division of Cardiology, Department of Medicine, Cardiovascular Research Laboratory, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, USA; Jonsson Comprehensive Cancer Center, USA; Molecular Biology Institute, USA; Program in Molecular Cellular & Integrative Physiology, David Geffen School of Medicine at University of California, Los Angeles, USA; Program in Cell & Developmental Biology, David Geffen School of Medicine at University of California, Los Angeles, USA. Electronic address: - - 2014
Cardiac fibroblasts are the most abundant cell type in the mammalian heart and comprise approximately two-thirds of the total number of cardiac cell types. During development, epicardial cells undergo epithelial-mesenchymal-transition to generate cardiac fibroblasts that subsequently migrate into the developing myocardium to become resident cardiac fibroblasts. Fibroblasts form a structural ...
Robbers Lourens F H J LF From the Department of Cardiology, VU University Medical Center, Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands (L.F.H.J.R., R.N., A.M.B., M.B.M.H., A.C.v.R.); ICIN-Netherlands Heart Institute (ICIN-NHI), Utrecht, the Netherlands (L.F.H.J.R., R.N., A.H., A.M.v.d.L., R.D., P.A.v.d.V.); Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands (A.H., A.M.v.d.L., R.D., J.G.P.T., J.J.P.); Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (P.A.v.d.V., R.A.T.); and Department of Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands - - 2014
Purpose To investigate the effects of cell therapy on myocardial perfusion recovery after treatment of acute myocardial infarction (MI) with primary percutaneous coronary intervention (PCI). Materials and Methods In this HEBE trial substudy, which was approved by the institutional review board (trial registry number ISRCTN95796863), the authors assessed the effects ...
Nirupam Nilay N Department of Pediatrics, Division of Neonatology, LHMC and Kalawati Saran Children's Hospital, New Delhi, India. Correspondence to: Dr Nilay Nirupam, Senior Resident, Department of Pediatrics, Lady Hardinge Medical College, New Delhi 110001, India. - - 2014
Perinatal asphyxia is known to precipitate myocardial dysfunction, rhythm abnormalities and congestive cardiac failure. A 2-day old neonate with perinatal asphyxia. He developed shock secondary to ventricular tachycardia, and required synchronized cardioversion for reversion of abnormal rhythm. Reversal of arrhythmia leading to recovery. Early identification and management of ventricular tachycardia ...
Bhakri Kp K National Heart & Lung Institute, Imperial College London, London, - - 2014
The use of cardioplegia solution has substantially increased the safety of cardiac surgery. It protects the myocardium by inducing a rapid and complete diastolic arrest, minimizing myocardial energy requirements, preventing ischaemic damage during the arrest phase and minimizing or preventing reperfusion injury once coronary blood flow is restored.This article is ...
Sohal Manav M 1Division of Imaging Sciences and Biomedical Engineering, King's College & Cardiovascular Department, Guy's and St. Thomas' NHS Foundation Trust, London, United - - 2014
-We sought to compare left ventricular (LVepi) and biventricular epicardial pacing (BIVepi) with left ventricular (LVendo) and biventricular endocardial pacing (BIVendo) in patients with chronic heart failure with an emphasis on the underlying electrophysiological mechanisms and hemodynamic effects. -10 patients with chronically implanted cardiac resynchronization devices underwent temporary LVendo and ...
Bell James R JR University of - - 2014
Estrogen in females is conventionally considered a cardioprotective influence, though a role for estrogen in male cardioprotection has yet to be defined. Estrogen biosynthesis from testosterone is regulated by aromatase. Aromatase has recently been shown to be expressed in the adult heart, though little is known about its involvement in ...
Schlitt Axel A Paracelsus Harz Clinic Bad Suderode, Quedlinburg: Prof. Dr. med. habil. Schlitt, MHA, Faculty of Medicine, Martin Luther-Universität Halle-Wittenberg, Department IV of Internal Medicine, University Clinic Halle (Saale), Martin Luther-Universität Halle-Wittenberg, Department of Radiotherapy, University Clinic Halle (Saale), Martin Luther-Universität Halle-Wittenberg, Department of Pediatric Hematology and Oncology, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany, Department of Gynecology and Obestetrics, University Clinic Halle (Saale), Martin Luther-Universität - - 2014
Cardiotoxic and other side effects limit the usefulness of treatments for cancer. This article is based on pertinent articles that were retrieved by a selective search in PubMed and other databases, and on the guidelines of the European Society of Cardiology, the Association of Scientific Medical Societies in Germany, and ...
Pisarenko O I OI Laboratory for Myocardial Metabolism, Russian Cardiology Research-and-Production Complex, 3rd Cherepkovskaya Str., 15A, 121552, Moscow, Russian Federation, - - 2014
This study investigated the effects of peptide apelin-12 (H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, A12) and its novel structural analog (H-(N(α)Me)Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Nle-Pro-Phe-OH, AI) on myocardial antioxidant enzyme activities, lipid peroxidation, and reactive oxygen species formation in ex vivo and in vivo models of myocardial ischemia/reperfusion (I/R) injury. Isolated working rat hearts were subjected to global ischemia ...
Sohal Manav M Division of Imaging Sciences and Biomedical Engineering, King's College London, Rayne Institute, 4th Floor Lambeth Wing, St. Thomas' Hospital, London SE1 7EH, - - 2014
Cardiac resynchronization therapy (CRT) is a proven treatment adjunct for selected patients with heart failure and evidence of ventricular dyssynchrony. When applying most contemporary guidelines the accepted response rate has remained static with up to one-third of patients failing to respond. Empiric lateral/posterolateral lead positioning may not be the optimal ...
Dickover Michael M Department of Medicine, Division of Cardiology, University of California, San Diego, La Jolla, California - - 2014
The vertebrate heart undergoes early complex morphologic events in order to develop key cardiac structures that regulate its overall function (Fahed et al., 2013). Although many genetic factors that participate in patterning the heart have been elucidated (Tu and Chi, 2012), the cellular events that drive cardiac morphogenesis have been ...
Ellis Ethan R ER Harvard-Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: - - 2014
Ventricular arrhythmias in the absence of structural heart disease are commonly referred to as "idiopathic". Patients with structural heart disease have ventricular arrhythmias with the same mechanisms and sites of origin as "idiopathic" ventricular arrhythmias but the prevalence of such arrhythmias is not well defined. To identify the prevalence of ...
Menendez-Castro Carlos C Department of Pediatrics and Adolescent Medicine, , University of Erlangen-Nürnberg, 91054 Erlangen, - - 2014
Background:Intrauterine growth restriction (IUGR) is an important risk factor for cardiovascular disease. Previous studies revealed altered myocardial matrix composition after IUGR. We hypothesized that IUGR is accompanied by compromised myocardial performance independently from arterial hypertension.Methods:IUGR was induced in Wistar rats by maternal protein restriction and hearts of male offspring were ...
Cho Yasunori Y Department of Cardiovascular Surgery, Tokai University School of Medicine, Kanagawa, - - 2014
We retrospectively analyzed the long-term outcomes and risk predictors of conventional coronary artery bypass grafting routinely employed for patients with left main disease. From January 2000 through December 2009, conventional coronary artery bypass grafting was routinely employed in 193 consecutive patients with left main disease. Long-term analyses were performed, looking ...
Melo Stéphano F S SF Laboratory of Biochemistry and Molecular Biology of the Exercise, Department of Human Movement Biodynamic, School of Physical Education and Sport University of São Paulo, - - 2014
Background: Myocardial infarction (MI) is accompanied by cardiac growth, increased collagen deposition, cell death and new vascularization of the cardiac tissue, which results in reduced ventricular compliance. The MiRNA-29 family (29a, 29b, and 29c) targets mRNAs that encode collagens and other proteins involved in fibrosis. In this study we assessed ...
Cui Haitao H Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences , Changchun 130022, People's Republic of - - 2014
Injectable hydrogels made of degradable biomaterials can function as both physical support and cell scaffold in preventing infarct expansion and promoting cardiac repair in myocardial infarction therapy. Here, we report in situ hydrogels consisting of thermosensitive PolyNIPAM-based copolymers and electroactive tetraaniline (TA). Studies showed that the addition of 2-methylene-1,3-dioxepane (MDO) ...
Bhushan Shashi S Pharmacology, LSU Health Sciences - - 2014
Nitric oxide (NO) bioavailability is reduced in the setting of heart failure. Nitrite (NO2) is a critically important NO intermediate that is metabolized to NO during pathological states. We have previously demonstrated that sodium nitrite ameliorates acute myocardial ischemia/reperfusion (MI/R) injury. No evidence exists as to whether increasing NO bioavailability ...
Goichberg Polina P Brigham and Women's Hospital, 75 Francis St, Thorn Building, room 1334A, Boston, Massachusetts, United States, 02115, 1-617-278-0088 ; - - 2014
Significance: Heart disease is the primary cause of death in the industrialized world. Cardiac failure is dictated by an uncompensated reduction in the number of viable and fully-functional cardiomyocytes. While current pharmacological therapies alleviate the symptoms associated with cardiac deterioration, heart transplantation remains the only therapy for advanced heart failure. ...
Demirpençe Savaş S Clinic of Pediatric Cardiology, İzmir Buca Gynecology and Obstetrics and Pediatric Diseases Hospital, İzmir-Turkey. - - 2014
OBJECTIVE:One-quarter of deaths in children with chronic renal failure is due to cardiovascular complications. Conventional echocardiographic methods are insufficient for evaluating systolic functions in children with chronic renal failure. The aim of the present study was to investigate cardiac functions in children with chronic renal failure by evaluating left atrial ...
Zhang Lu L Department of Developmental and Regenerative Biology, The Mindich Child Health and Development Institute, and The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, - - 2014
The vertebrate heart develops from mesoderm and requires inductive signals secreted from early endoderm. During embryogenesis, Nkx2.5 acts as a key transcription factor and plays essential roles for heart formation from Drosophila to human. In mice, Nkx2.5 is expressed in the early first heart field, second heart field pharyngeal mesoderm, ...
Nattel Stanley S Department of Medicine and Research Center, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada. Electronic address: - - 2014
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. AF and its complications are responsible for important population morbidity and mortality. Presently available therapeutic approaches have limited efficacy and nontrivial potential to cause adverse effects. Thus, new mechanistic knowledge is essential for therapeutic innovation. Atrial arrhythmogenic remodeling, ...
Bradfield Jason S JS UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine at UCLA, Los Angeles, - - 2014
The objective of this study was to determine whether premature ventricular contractions (PVCs) arising from the aortic sinuses of Valsalva (SOV) and great cardiac vein (GCV) have coupling interval (CI) characteristics that differentiate them from other ectopic foci. PVCs occur at relatively fixed CI from the preceding normal QRS in ...
Vitali Francesca - - 2014
Surfactant treatment reduces respiratory morbidity and mortality in preterm infants. Data on its haemodynamic consequences are conflicting. The aim was to characterise the haemodynamic effects of surfactant treatment on cardiac function in preterm newborns with respiratory distress syndrome (RDS). Preterm infants (gestational age <34 weeks, birth weight <2000 g) with ...
Pérez Matos A J AJ Department of Cardiology, St. Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, the - - 2014
Patients with congenital heart disease corrected in early childhood may later in life present with cardiac symptoms caused by other associated congenital anomalies that were initially not diagnosed. Nowadays, several noninvasive imaging modalities are available for the visualisation of cardiac anatomy in great detail. We describe two patients with an ...
Dahlslett Thomas T Sørlandet Hospital, Arendal, - - 2014
Many patients with suspected non-ST-segment elevation acute coronary syndrome (NSTE-ACS) do not have significant coronary artery disease. The current diagnostic approach of repeated electrocardiography and cardiac biomarker assessment requires observation for >6 to 12 hours. This strategy places a heavy burden on hospital facilities. The objective of this study was ...
Pazzi Paolo - - 2014
A 3-week-old female white Bengal Tiger cub (Panthera tigris tigris) presented with acute onset tachypnoea, cyanosis and hypothermia. The cub was severely hypoxaemic with a mixed acid-base disturbance. Echocardiography revealed severe pulmonic stenosis, right ventricular hypertrophy, high membranous ventricular septal defect and an overriding aorta. Additionally, an atrial septal defect ...
Jiang Yan Y Institute of Genetic Medicine and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom; Soochow University, Su Zhou, China; Princess Al Jawhara Center of Excellence in Research, King Abdulaziz University, Jeddah, Saudi Arabia; Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic; Institute of Cardiovascular Science, Manchester Academic Health Science Centre, CoreTechnology Facility, Manchester, United Kingdom; School of Biomedical Sciences, University of Durham, Durham, United Kingdom; Department of Human Genetics, University of Kragujevac, Kragujevac, - - 2014
Hypoplastic left heart syndrome (HLHS) is a serious congenital cardiovascular malformation resulting in hypoplasia or atresia of the left ventricle, ascending aorta, and aortic and mitral valves. Diminished flow through the left side of the heart is clearly a key contributor to the condition, but any myocardial susceptibility component is ...
Fillmore Natasha N Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, - - 2014
Alterations in cardiac energy metabolism are an important contributor to the high incidence and severity of heart disease in the world. These alterations can include an impairment of the production of ATP necessary to meet the high energy demands of the heart, as well as adverse switches in energy substrate ...
Gilje Patrik - - 2014
Early prognostication after successful cardiopulmonary resuscitation is difficult and there is a need for novel methods to estimate the extent of brain injury and predict outcome. In this study, we evaluate the impact of the cardiac arrest syndrome on the plasma levels of selected tissue-specific microRNAs (miRNAs) and assess their ...
Wijesekera Vishva A - - 2014
Coronary revascularization in resuscitated out of hospital cardiac arrest (OOHCA) patients has been associated with improved survival. This was a retrospective review of patients with OOHCA between 01/07/2007 and 31/03/2009 surviving to hospital admission. Cardiac risk factors, demographics, treatment times, electrocardiogram (ECG), angiographic findings and in-hospital outcomes were recorded. Of ...
Hesse Michael M Institute of Physiology 1, Life and Brain Center, University of Bonn, 53105, Bonn, - - 2014
Ischemic heart disease is the number one cause of morbidity and mortality in the developed world due to the inability of the heart to replace lost myocytes. The cause of post-infarction myogenic failure has been a subject of intense scientific investigation and much controversy. Recent data indicate a brief perinatal ...
Takashio Seiji S Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, - - 2014
Persistently high cardiac troponin T (cTnT) levels reflect myocardial damage in heart failure (HF). The presence and extent of myocardial fibrosis assessed by cardiac magnetic resonance (CMR) and high levels of cTnT predict poor prognosis in various cardiomyopathies. However, the association between myocardial fibrosis and transcardiac cTnT release has not ...
Huded Chetan P CP Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, - - 2014
Transradial (TR) cardiac catheterization is effective and offers lower rates of vascular complications and bleeding compared with transfemoral cardiac catheterization. We sought to describe the safety and feasibility of TR cardiac catheterization in liver transplant candidates (LTCs). We retrospectively reviewed 1,071 consecutive cases of TR cardiac catheterization in 1,045 patients ...
Chan Dulciana D DD Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, United States Food and Drug Administration, Silver Spring, - - 2014
QRS duration (QRSd) is used to diagnose left bundle branch block (LBBB) and is important to determine cardiac resynchronization therapy eligibility. The same QRSd thresholds established decades ago are used for all patients. However, significant interpatient variability of normal QRSd exists, and individualized QRSd thresholds might improve diagnosis and intervention ...
Lenneman Andrew J AJ Division of Cardiovascular Medicine, University of Louisville, Rudd Heart and Lung Center, 201 Abraham Flexner Way, Suite 1001, Louisville, KY, 40202, USA, - - 2014
Heart failure is a progressive disorder characterized by adverse left ventricular remodeling. Until recently, this has been thought to be an irreversible process. Mechanical unloading with a left ventricular assist device (LVAD), particularly if combined with neurohormonal blockade with heart failure medications, can lead to a reversal of the heart ...
Tanawuttiwat Tanyanan T Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Carnegie 568, Baltimore, MD, 21287, - - 2014
The benefits of cardiac resynchronization therapy (CRT) are well-established, with the majority of large clinical trials focused on individuals with advanced systolic heart failure and patients with prolonged QRS duration. The favorable outcomes from CRT have been expanded from initial investigations in patients with severe heart failure to those with ...
Gulati Vinay V From the *Department of Medicine, University of Connecticut Health Center, Farmington, CT; and †Division of Cardiology, Department of Medicine, New York Medical College/Westchester Medical Center, Valhalla, - - 2014
Cardiac hemochromatosis or primary iron-overload cardiomyopathy is an important and potentially preventable cause of heart failure. This is initially characterized by diastolic dysfunction and arrhythmias and in later stages by dilated cardiomyopathy. Diagnosis of iron overload is established by elevated transferrin saturation (>55%) and elevated serum ferritin (>300 ng/mL). Genetic ...
Grobben Remco B RB Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address: - - 2014
Differentiation between procedure-related necrosis and postprocedural myocardial infarction (MI) is challenging because of the inherent association of these procedures to varying levels of myocardial injury. To improve risk stratification of patients at risk of an acute MI, the universal definition of MI implemented cardiac biomarker thresholds. The cutoff points for ...
Blick Kenneth E KE Department of Pathology, College of Medicine, OU Medical Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Electronic address: - - 2014
Delays in diagnosis and treatment of cardiac patients presenting in the Emergency Department with symptoms of acute coronary syndromes are associated with poorer patient outcomes; hence, the timely and accurate diagnosis in the Emergency Department now requires the 24/7 availability of real-time, rapid testing for cardiac markers. Cardiac troponin (cTnI) ...
Jarolim Petr P Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: - - 2014
Cardiac troponins I and T have been the cornerstone of diagnostics of acute coronary syndrome for almost 20 years. Natriuretic peptides have established themselves in heart failure during the last decade. These and additional promising biomarkers, such as ST-2, galectin-3, GDF-15, copeptin, midregional proadrenomedullin, and the markers of glomerular filtration rate ...
Conrad Michael J MJ Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Harvard Medical School, Boston, MA 02115, - - 2014
Measurement of circulating cardiac troponins I and T has become integral to the diagnosis of myocardial infarction. This article discusses the structure and function of the troponin complex and the release of cardiac troponin molecules from the injured cardiomyocyte into the circulation. An overview of current cardiac troponin assays and ...
Lewandrowski Kent B KB Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Gray 5 Chemistry, Boston, MA 02114, USA. Electronic address: - - 2014
Laboratory testing for blood-based biomarkers of myocardial injury has steadily evolved over the past 60 years. Initial assays were cumbersome and were neither sensitive nor specific for myocardial necrosis. Major improvements have included the development of more cardiospecific markers, the introduction of random access immunoassays that facilitated near-real-time reporting of results, ...
Safdar Basmah B From the Departments of *Emergency Medicine and ‡Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT; †Department of Emergency Medicine, Baylor School of Medicine, Houston, TX; §Brown University School of Medicine, Providence, RI; and ¶Yale Center for Analytical Sciences, New Haven, - - 2014
Prior studies indicate that an elevated creatinine kinase (CK)-MB imparts poor prognosis in patients with acute coronary syndrome despite a normal troponin. Its prognosis in the undifferentiated chest pain observation unit (CPU) population remains undefined. To compare rates and predictors of 30-day adverse cardiac events in 2 cohorts (CK±/MB+ vs. ...
Luo Haijian H Department of Physiology, Shihezi University School of Medicine, Shihezi, Xinjiang 832003, P.R. China ; Department of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214023, P.R. China ; Institute of Cardiovascular Sciences, The University of Manchester, Manchester M13 9PL, - - 2014
Cardiac electrophysiological heterogeneity related to the washout of acetylcholine (ACh) remains incompletely characterized. The aim of this study was to examine whether positive cardiac inotropic action is associated with electrophysiological heterogeneity between the atrium and the ventricle after ACh perfusion and washout. Epicardial monophasic action potentials (MAPs) from the right ...
Thanaviratananich Sikawat S *Department of Neurology, SSM Neurosciences Institute and St. Louis University, St. Louis, MO; and †Neurological Institute, University Hospitals Case Medical Center, Cleveland, - - 2014
Myocardial pathology is rarely associated with myasthenia gravis (MG). We describe a case of newly diagnosed MG with decompensated heart failure [stress-induced cardiomyopathy (SICM)] that occurred during the crisis phase. Case report and review of literature. A 42-year-old woman underwent chemotherapy followed by a transsternal resection of a malignant epithelioid ...
Lavine Elyse E Department of Emergency Medicine, Emergency Ultrasound Division, St. Luke's / Roosevelt Hospital Center, New York, New York, - - 2014
Cardiac amyloidosis is a disease process of abnormal amyloid fibril deposition in cardiac muscle that can be diagnosed by specific electrocardiographic and echocardiographic findings. We present the case of a patient with a history of cardiac amyloidosis who presented to the emergency department (ED) with shortness of breath, and was ...
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