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Penciu Oana-Maria OM Department of Internal Medicine, Western Connecticut Health Network, Danbury Hospital, Danbury, - - 2014
Hypertrophic cardiomyopathy and anomalous origin of the coronary artery from the opposite sinus are common causes of sudden cardiac death. These entities have rarely been reported together. Here we present the case of a 48-year-old woman with hypertrophic cardiomyopathy and significant left ventricular outflow tract obstruction. She was referred for ...
Saxena Amit A The Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx - - 2014
The CXC chemokine CXCL10 is upregulated in the infarcted myocardium and limits cardiac fibrosis by inhibiting growth factor-mediated fibroblast migration. CXCL10 signals by binding to its receptor CXCR3; however, recently CXCR3-independent CXCL10 actions have been suggested. Our study explores the role of CXCR3 signaling in myocardial infarction and investigates its ...
Ulusoy Sükrü S Karadeniz Technical - - 2014
Background-Kidney transplant is a most important replacement therapy. It reduces cardiovascular mortality and morbidity but does not fully correct impairments in cardiac function. Fragmented QRS (fQRS) complex includes various RSR' patterns with different QRS complex morphologies on electrocardiograms.Objective-To analyze fQRS frequency and the relationship between fQRS and left ventricular function ...
Waltenberger Johannes J Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany. Electronic address: - - 2014
Intermittent dyssynchrony, induced by ventricular pacing, during early reperfusion reduces infarct size in pre-clinical studies. We evaluated cardioprotection by pacing post-conditioning (PPC) in ST-segment elevation myocardial infarction in a randomized, controlled, single-center, single-blinded, first-in-man study. Patients with first ST-segment elevation myocardial infarction received either PPC plus percutaneous coronary intervention (PCI) (n = ...
Hill Stanley E SE Critical Care Pharmacy Specialist, Long Beach Memorial Medical Center, Department of Inpatient Pharmacy, 2801 Atlantic Ave. Long Beach, CA, 90806. - - 2014
Migraine is a potentially debilitating neurologic disorder affecting approximately 12% of the United States population. Sumatriptan manufacturer-provided drug information states that life threatening arrhythmias, including ventricular tachycardia and ventricular fibrillation (VF), have been reported. A literature search revealed only seven reported cases of ventricular arrhythmias immediately after sumatriptan administration. Twenty ...
Sun Haihui H Department of Cardiology, The Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China ; Department of Cardiology, The Central Hospital of Tai'an, Tai'an, Shandong 271000, P.R. - - 2014
The aim of the present study was to investigate major cardiac events and the similarities and differences of medical costs among patients with multivessel complex coronary artery disease (MCCAD) during the three-year follow-up. The MCCAD patients had undergone single complete revascularization (CR), fractionated revascularization (FR) or partial revascularization (PR) and ...
Kydd Anna C AC Department of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United - - 2014
This study was conducted to assess the impact of left ventricular (LV) lead position on longer-term survival after cardiac resynchronization therapy (CRT). An optimal LV lead position in CRT is associated with improved clinical outcome. A strategy of speckle-tracking echocardiography can be used to guide the implanter to the site ...
Mosalpuria Kailash K Departments of Internal Medicine (Dr. Mosalpuria) and Cardiology (Dr. Pierre-Louis), Harlem Hospital Center affiliated with Columbia University, New York, New York 10037; Department of Medicine (Drs. Agarwal and Russell), Johns Hopkins University, Baltimore; Maryland 21205; Department of Epidemiology (Dr. Yaemsiri), University of North Carolina, Chapel Hill, North Carolina 27599; and Cardiovascular Institute (Drs. Agarwal, Alvarez, and Saba), University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania - - 2014
Better outpatient management of heart failure might improve outcomes and reduce the number of rehospitalizations. This study describes recent outpatient heart-failure management in the United States. We analyzed data from the National Ambulatory Medical Care Survey of 2006-2008, a multistage random sampling of non-Federal physician offices and hospital outpatient departments. ...
Budoff Matthew J MJ Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California - - 2014
Atrial volumetric measurement has proven clinical implications. Advances in cardiac imaging, notably the precision enabled by multidetector computed tomography (MDCT), herald the need for new criteria of what constitutes normal volumetric measurements. With use of 64-slice MDCT, we compared the atrial volumes in healthy individuals with those in individuals with ...
Darda Saba S Department of Cardiology, Providence Hospital and Medical Center, South-field, Michigan - - 2014
In patients with cardiac sarcoidosis, the sarcoid granulomas usually involve the myocardium or endocardium. The disease typically presents as heart failure with ventricular arrhythmias, conduction disturbances, or both. Constrictive pericarditis has rarely been described in patients with sarcoidosis: we found only 2 reports of this association. We report the case ...
Martinez Sara C SC Department of Internal Medicine, Cardiovascular Division (Drs. Bradley, Cedars, Ewald, Joseph, Martinez, and Rasalingam; and Mr. Novak), and Department of Surgery, Division of Cardiothoracic Surgery (Dr. Silvestry), Washington University School of Medicine in St. Louis, St. Louis, Missouri - - 2014
Left ventricular assist device (LVAD)-supported patients are evaluated routinely with use of transthoracic echocardiography. Values of left ventricular unloading in this unique patient population are needed to evaluate LVAD function and assist in patient follow-up. We introduce a new M-mode measurement, the slope of the anterior mitral valve leaflet (SLAM), ...
Ha Chung-Eun CE Department of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI - - 2014
This article describes an interesting case of a patient presenting with congestive heart failure found to have restrictive cardiomyopathy with initial laboratory evaluation showing hypogammaglobuminemia without a monoclonal band on serum and urine electrophoresis. This case highlights the clinically significant cardiac manifestation caused by protein misfolding, a defect in protein ...
Hiemstra Jessica A JA Department of Biomedical Science, University of Missouri- Columbia, 1600 E. RollinsW160 Veterinary Medicine, Columbia, - - 2014
We recently developed a clinically relevant mini-swine model of heart failure with preserved ejection fraction (HFpEF), in which diastolic dysfunction was associated with increased mitochondrial permeability transition (MPT). Early diastolic function is ATP and Ca(2+)-dependent, thus, we hypothesized chronic low doses of cyclosporine (CsA) would preserve mitochondrial function via inhibition ...
Flessas Nikolaos N aDepartment of Cardiology, Sotiria Hospital of Chest Diseases bDepartment of Cardiology, Athens University Hospital Attikon, Athens, - - 2014
Plasma B-type natriuretic peptide (BNP) is an established prognostic indicator in patients with left ventricular systolic heart failure (LHF). However, no efficient data exist regarding the differences in plasma BNP activity between patients with biventricular heart failure and those with right heart failure (RHF) due to chronic obstructive pulmonary disease ...
Ghio Stefano S aDivisione di Cardiologia bServizio di Analisi Chimico Cliniche cDipartimento di Biometria ed Epidemiologia Clinica, Fondazione IRCCS Policlinico San Matteo, Pavia, - - 2014
To verify whether a combined assessment of left-ventricular filling pattern at Doppler echocardiography, plasma levels of brain natriuretic peptide (BNP) and high-sensitive troponin I (hsTnI) improves prognostic stratification in patients with chronic systolic heart failure. Three predictors of prognosis were evaluated in 200 consecutive outpatients with heart failure and left-ventricular ...
Löfsjögård Johan J aDivision of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet bDepartment of Cardiology, Danderyd University Hospital, Stockholm, Sweden cDivision of Cardiovascular Sciences, Centre of Applied Medical Research dDepartment of Cardiology and Cardiac Surgery, School of Medicine, University of Navarra, Pamplona, Spain eErsta Hospital, Stockholm, - - 2014
Myocardial collagen metabolism can be assessed indirectly by circulating biomarkers. We aimed to examine associations between myocardial collagen type I synthesis and degradation, and echocardiographic, clinical, and B-type natriuretic peptide (BNP) findings in heart failure. We studied 57 women and 75 men 60 years or older with systolic heart failure ...
Benato Livia - - 2014
Cardiac disease is a common finding in small mammals but it is rarely reported in striped skunks (Mephitis mephitis). The aim of this survey was to evaluate the prevalence of cardiac disease in striped skunks and to characterize the types of cardiac disease that might be present. In April 2010, ...
Arndt-H Kiessling K Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, - - 2014
Background: Myoglobin has become established as a serum marker of myocardial injury. However, myoglobin levels can increase exponentially without any correlation to postoperative clinical ischemia symptoms. In this retrospective study, we analyzed the associated factors for a non-ischemic myoglobin release.Methods: We performed a data analysis from 532 consecutive cardiac surgery ...
Ho Joanne M JM Sunnybrook Health Sciences Centre, G Wing 106, 2075 Bayview Ave, Toronto, Ontario M4N 3M5, Canada - - 2014
Venlafaxine is a commonly prescribed antidepressant, but whether its noradrenergic effects impart increased cardiovascular risk is unknown. We sought to examine the cardiac safety of venlafaxine relative to sertraline in older patients. We conducted a population-based retrospective cohort study using administrative health care databases in Ontario, Canada. We included all ...
Lynch Joseph P JP 3rd Division of Pulmonary, Critical Care Medicine, Allergy, and Clinical Immunology, David Geffen School of Medicine at UCLA, Los Angeles, - - 2014
Clinically evident sarcoidosis involving the heart has been noted in at least 2 to 7% of patients with sarcoidosis, but occult involvement is much higher (> 20%). Cardiac sarcoidosis is often not recognized antemortem, as sudden death may be the presenting feature. Cardiac involvement may occur at any point during ...
Wilson Mark M University of Illinois at Chicago, Chicago, IL, - - 2014
The main objective of this study is to investigate the effects of chronic and acute stress on blood pressure, heart rate variability and an indicator of cardiac contractility. The study also aims to describe the degree to which various demographic and lifestyle factors modify the observed effect. Chronic stress was ...
Shamim Shariq S 1 Cardiology Fellow University of Missouri, Kansas City, USA ; 2 Quality Improvement Director, Cardiology Section Truman Medical Center, USA ; 3 Professor and Chief of the Emergency Department University of Missouri, Kansas City and Truman Medical Center, USA ; 4 Formerly Associate Professor of Medicine University of Missouri, Kansas City and Chief of Cardiology of Truman Medical Center (Retired), - - 2014
Prompt reperfusion has been shown to improve outcomes in patients with acute ST-segment elevation myocardial infarction (STEMI) with a goal of culprit vessel patency in <90 minutes. This requires a coordinated approach between the emergency medical services (EMS), emergency department (ED) and interventional cardiology. The urgency of this process can ...
Zaman Maseeh Uz MU 1 Department of Radiology, The Aga Khan University Hospital (AKUH), Karachi, Pakistan ; 2 Department of Nuclear Cardiology, Karachi Institute of Heart Diseases (KIHD), Karachi, Pakistan ; 3 Department of Nuclear Medicine, Dr Ziauddin Medical University, Karachi, Pakistan ; 4 MBBS Students, Dow University of Health Sciences (DUHS), Karachi, - - 2014
The negative predictive value of a normal single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is very high. However, prognostic implication of a normal SPECT MPI in patients with known coronary artery disease (CAD) is not clear. Objective of this study was to evaluate the cardiac event rate in ...
Dear J J North Middlesex University Hospital, London, - - 2014
To report the rare case of a woman who was induced at term for deranged liver function, was later was recognised as secondary to cardiac dysfunction and a literature review of this rare condition. We reviewed the case notes and investigations of the above woman and collected the demographic details, ...
O'Dwyer Sl S Department of Obstetrics and Gynecology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa Whipps Cross University Hospital, Barts Health NHS Trust, London, - - 2014
To describe the aetiology and obstetric outcome in women presenting with pulmonary oedema during pregnancy and the puerperium. Retrospective case note analysis of 53 cases of pulmonary oedema causing significant respiratory distress and admission to intensive care at the Groote Schuur Hospital in Cape Town, South Africa. Cases could be ...
Spooner L L University Hospital Coventry Warwickshire, Coventry, - - 2014
All pregnant women are offered an anomaly scan including assessment of fetal cardiac anatomy. Congenital cardiac disease is a complex structural malformation of the heart and/or great arteries requiring surgical/catheter intervention within the first 6 months.(1) We reviewed the spectrum of defects diagnosed antenatally at our teaching hospital from 2011-2013 ...
Climov Daniela - - 2014
Biofeedback is a self-regulation therapy by which the patient learns how to optimize the functioning of his autonomic nervous system. It has been applied to patients with various cardiovascular disorders. The purpose of this study was to investigate the practical feasibility and the psychophysiological effects of biofeedback applied to heart ...
Husain Nazia - - 2014
Echocardiographic evaluation of systolic function in patients with single right ventricles (SRV) is important but remains challenging. Minimal data exist correlating echocardiographic indices with catheterization data in this population. The goal of this study was to evaluate which echocardiographic measurement correlated best with dP/dt (max) obtained by cardiac catheterization in ...
Yıldız Kemal K Department of Gastroenterology, Bezmialem Vakif University Medical School, İstanbul, Turkey. - - 2014
Some patients may experience retrosternal pain during ERCP, which may be a pioneer of a serious myocardial problem, and early diagnosis is very important for the prognosis and management. In the study, we aimed to investigate the role of serum cardiac biomarkers, such as myeloperoxidase (MPO), creatine phospokinase (CPK), creatine ...
Rosenblatt Jeffrey J Maine Medical Center, Department of Cardiac Services, Tufts University School of Medicine, 22 Bramhall St, 119 Gannett Drive, Portland, ME, 04106, USA, - - 2014
Regadenoson is a selective A2A receptor agonist approved for use as a pharmacologic stress agent for myocardial perfusion imaging after several multicenter trials demonstrated its equivalence in diagnostic accuracy for the detection of coronary artery disease and a decreased incidence of serious side effects as compared to adenosine. Recently, the ...
Dellegrottaglie S S Division of Cardiology, Ospedale Medico-Chirurgico Accreditato Villa dei Fiori, C.so Italia, 157, 80011, Naples, Acerra, Italy, - - 2014
We report the case of a 32-year-old male with Chlamydia trachomatis infection and admitted with chest pain, signs of myocardial damage and coronary arteries free from significant atherosclerotic disease. Cardiac magnetic resonance imaging (MRI) documented imaging patterns of myocardial involvement suggestive of acute myocarditis, and repeated cardiac MRI examinations were ...
Lemkes Jorrit J Department of Cardiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, - - 2014
Patients with chest pain and a prehospital ST-segment elevation myocardial infarction (STEMI) are preferably treated with immediate percutaneous coronary intervention (PCI). However, patients with normalization of symptoms and ST-segment elevation upon hospital arrival (transient STEMI) received inconsistent therapy due to logistic reasons and the absence of evidence or explicit guidelines. ...
Chow Grant V GV Division of Cardiology, Johns Hopkins Medical Institutions, The Johns Hopkins University School of Medicine; Baltimore, - - 2014
Patients with acute MI, left bundle branch block (LBBB), and marked LV de-compensation suffer nearly 50% early mortality. Whether CRT improves hemodynamic status in this condition is unknown. We tested CRT in this setting, using a canine model of delayed lateral wall activation combined with 2-hours of coronary artery occlusion-reperfusion. ...
Benezet-Mazuecos Juan J Department of Cardiology, Hospital Universitario Fundación Jiménez Díaz-IDCsalud, Universidad Autónoma de Madrid, Madrid, - - 2014
Assessment of the prevalence of silent paroxysmal atrial fibrillation (AF) represents a challenge, since the arrhythmia may be brief, completely asymptomatic, and difficult to detect. Lack of symptoms from AF should not be equated to lack of risk of thromboembolic complications. Today's cardiac implantable electronic devices (CIED) diagnostics include system ...
Backhoff David D Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University, Robert-Koch-Str 40, 37075, Göttingen, - - 2014
Years and decades after the Mustard atrial switch repair for d-Transposition of the great arteries, there is a subset of patients at increased risk for sudden cardiac death due to ventricular tachyarrhythmias. To date, little is known about indications, efficacy and benefit of internal cardioverter defibrillator (ICD) therapy indication in ...
Genet Martin M - - 2014
Ventricular wall stress is believed to be responsible for many physical mechanisms taking place in the human heart, including ventricular remodeling, which is frequently associated with heart failure. Therefore, normalization of ventricular wall stress is the cornerstone of many existing and new treatments for heart failure. In this paper, we ...
Matsushita Kunihiro K From the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (K.M., Y.S., S.H.B., M.W., J.C.); Department of Medicine and Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison (B.C.A.); Department of Medicine, Section of Atherosclerosis and Vascular Medicine, Baylor College of Medicine, and the Methodist DeBakey Heart and Vascular Center, Houston, TX (R.C.H., C.M.B.); Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.D.S.). - - 2014
Traditional predictors suboptimally predict cardiovascular disease (CVD) in individuals with chronic kidney disease (CKD). This study compared 5 nontraditional cardiac and kidney markers on the improvement of cardiovascular prediction among those with CKD. Among 8622 participants aged 52 to 75 years in the Atherosclerosis Risk in Communities (ARIC) Study, cardiac ...
Esper Stephen A SA UPMC, Pittsburgh, PA, - - 2014
The techniques and equipment of cardiopulmonary bypass (CPB) have evolved over the past 60 years, and numerous numbers of cardiac surgical procedures are conducted around the world using CPB. Despite more widespread applications of percutaneous coronary and valvular interventions, the need for cardiac surgery using CPB remains the standard approach ...
Senanayake Eshan L EL Department of Cardiac Surgery, University Hospital Birmingham NHS Foundation Trust, Birmingham, - - 2014
Coronary artery disease in the donor heart is an established cause of early graft failure. However, identification of this before implantation is difficult. Cardiogenic shock associated with significant myocardial infarction during the early postoperative period is rare. Here, we report a case of a 42-year-old man who presented acutely with ...
Martindale Jennifer L JL Emergency Department, State University of New York Downstate, Kings County Hospital, Brooklyn, New - - 2014
To many physicians, hyperkalemia is the first diagnosis ascribed to any patient with end-stage renal disease and abnormal electrocardiographic morphologies or dysrhythmias. A 52-year-old man with end-stage renal disease presented in cardiac arrest. The patient was initially presumed to have hyperkalemia, based on the appearance of wide QRS complexes on ...
Hari Pawan P Division of Cardiology, Loma Linda University Medical Center, Loma Linda, - - 2014
Patent foramen ovale (PFO) is a common variant present in up to 25% of the population. Atrial septal defect (ASD) is a direct communication between the 2 atrial chambers, of which the ostium secundum variety is the most common. This manuscript is an in depth review of the complex atrial ...
Blei Francine F Vascular Birthmark Institute, St. Luke's Roosevelt Hospital, New York, New - - 2014
There is no uniform pretreatment cardiac evaluation for infants treated with oral propranolol, which is now the drug of choice for hemangiomas of infancy requiring systemic medical intervention. The aim of this study was to report and evaluate the findings of pretreatment cardiac evaluation. Data were reviewed for patients evaluated ...
Lin Kai K Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States. Electronic address: - - 2014
To test the hypothesis that biomechanical changes are quantitatively related to morphological features of coronary arteries in heart transplant (HTx) recipients. With IRB approval, three-dimensional (3D) magnetic resonance (MR) angiography and two-dimensional (2D) black-blood stead-state free precession (SSFP) MR imaging were performed to image coronary arteries of 36 HTx patients. ...
Kalogeropoulos Andreas P AP Division of Cardiology, Emory University, Atlanta, GA. Electronic address: - - 2014
Inotropes are widely used in hospitalized systolic heart failure (HF) patients, especially those with low systolic blood pressure (SBP) or cardiac index. Also inotropes are considered harmful in nonischemic HF. We examined the association of in-hospital inotrope use with (1) major events (death, ventricular assist device, or heart transplant) and ...
Lynch Thomas L TL Department of Cell and Molecular Physiology, Division of Cardiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, 60153, - - 2014
Cardiac myosin binding protein-C (cMyBP-C) is a regulatory protein of the contractile apparatus within the cardiac sarcomere. Ischemic injury to the heart during myocardial infarction (MI) results in the cleavage of cMyBP-C in a phosphorylation-dependent manner and release of an N-terminal fragment (C0C1f) into the circulation. C0C1f has been shown ...
Huang Lixing L State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen 361005, - - 2014
Growing evidence indicates that polycyclic aromatic hydrocarbons (PAHs) can lead to cardiac hypertrophy and recent research indicates that exposure to low dose crude oil during early embryonic development may lead to impacts on heart health at later life stages. The aim of this study was to evaluate whether exposure during ...
Dhein Stefan S Klinik für Herzchirurgie, Universität Leipzig, Herzzentrum, Struempellstr. 39, 04289, Leipzig, Germany, - - 2014
Mechanical stretch has been shown to provoke arrhythmia. We wanted to analyze ventricular arrhythmia induced by local left ventricular stretch in order to find out, where arrhythmias originate and whether they can be prevented pharmacologically. Isolated rabbit hearts (Langendorff technique) were submitted to increased left ventricular stretch at the left ...
Anderson Robert H RH Institute of Genetic Medicine, Newcastle University, Newcastle, United - - 2014
The past decades have seen immense progress in the understanding of cardiac development. Appreciation of precise details of cardiac anatomy, however, has yet to be fully translated into the more general understanding of the changing structure of the developing heart, particularly with regard to formation of the septal structures. In ...
Pfob Michael M CardioVital Institute of Preventive and Rehabilitation Medicine, Grieskirchnerstraße 49, 4600, Wels, Austria, - - 2014
In patients with coronary heart disease, both arterial stiffness and wave reflections are increased and predict unfavorable cardiovascular events. Cardiac rehabilitation has the goal to reduce risk factors and slow the progression of the disease. The aim of this study was to prospectively determine the impact of an ambulatory cardiac ...
Danese Elisa E Laboratory of Clinical Chemistry and Hematology, University of Verona , Verona , - - 2014
Atrial fibrillation (AF) is the most common among the severe cardiac arrhythmias and carries a significant risk of mortality and morbidity in the general population. The most important complication is represented by development of one or more thrombi in the left atrium of the dyskinetic heart, and their successive cerebral ...
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