Search Results
Results 1 - 50 of 1246
1 2 3 4 5 6 7 8 9 10 >
Santini L L Department of Cardiology, University of Tor Vergata, Rome, Italy - - - 2014
Quadripolar left ventricular (LV) leads offer multiple choices for LV pacing increasing programming flexibility. Aim of this study is to assess the influence of LV pacing vector selection on hemodynamic parameters for patients who underwent cardiac resynchronization therapy (CRT) using quadripolar LV lead chronically evaluated with a non--invasive approach by ...
Haugaard M M MM Department of Large Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, - - 2014
Only few pharmacologic compounds have been validated for treatment of atrial fibrillation (AF) in horses. Studies investigating the utility and safety of flecainide to treat AF in horses have produced conflicting results, and the antiarrhythmic mechanisms of flecainide are not fully understood. To study the potential of flecainide to terminate ...
Nakamura K K Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Veterinary Teaching Hospital, Sapporo, Hokkaido, - - 2014
A strong correlation between left atrial (LA) dysfunction and the severity of cardiac disease has been described in human patients with various cardiac diseases. The role of LA dysfunction in dogs with chronic mitral valvular heart disease (CMVHD) has not been addressed. To investigate the correlation between LA function and ...
Huang Ying Y Pu Dong New Area People's Hospital, Department of Cardiology , Huan-Nan Road 490#, Shanghai, 201200 , China +86 021 50331692 ; +86 021 50331692 ; - - 2014
Background: Although few microRNAs (miRNAs) have been involved in the regulation of post-ischemic cardiac fibrosis, the exact effect and underlying mechanism of miRNAs in cardiac fibrosis remains unclear. Here, we sought to investigate whether microRNA-34 (miR-34) plays a role in the pathogenic development of myocardial fibrosis. Methods: The myocardial infarction ...
Strom Joshua J Department of Pharmacology; College of Medicine, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ, 85724, - - 2014
Dodecafluoropentane emulsion (DDFPe) is a perfluorocarbon with high oxygen dissolving, transport, and delivery capacity that may offer the potential to limit ischemic injury prior to clinical reperfusion. Here we investigated the cardiac protective potential of DDFPe in a mouse model of myocardial infarction. Myocardial infarction was initiated by permanent ligation ...
Patra C - - 2014
Cardiovascular diseases present a major socio-economic burden. One major problem underlying most cardiovascular and congenital heart diseases is the irreversible loss of contractile heart muscle cells, the cardiomyocytes. To reverse damage incurred by myocardial infarction or by surgical correction of cardiac malformations, the loss of cardiac tissue with a thickness ...
Pokharel Parash P Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, 1650 Grand Concourse, 12th Floor, Bronx, NY 10457, - - 2014
Left ventricular (LV) torsion (twisting) and untwisting results in equalization of wall stress and augmentation of pressure generated for a given shortening of sarcomere during the systolic contraction and aids early diastolic relaxation. This is attributed to the dynamic interaction of epicardial and endocardial helical myocardial fibers. Recent advances in ...
Perugu S S Harbor-UCLA Medical Center, Torrance, CA, - - 2014
Evaluate plasma markers of myocardial function and ischemia [B-type natriuretic peptide] (BNP) and cardiac troponin T (cTnT)] in relationship to echocardiographic indices of left ventricular (LV) function and severity of illness score (SNAPPE-II) in Very-Low-Birth-Weight-Infants (VLBWIs) prospectively. Serial echocardiography studies, clinical data, BNP and cTnT were obtained in thirty VLBWIs ...
Chandraprakasam Satish S The Cardiac Center of Creighton University, 3006 Webster Street, Omaha, NE, 68131, USA, - - 2014
Heart failure (HF) continues to grow and affect more than five million people in the USA. One of the leading device therapies in HF is cardiac resynchronization therapy (CRT) which has been studied for over 20 years. Recent advancements in lead placement, lead technology, patient selection, and CRT optimization by electrical ...
Mafi Rad Masih M Maastricht University Medical Centre, Department of Cardiology, PO Box 5800, 6202 AZ, Maastricht, the - - 2014
Current targeted left ventricular (LV) lead placement strategy is directed at the latest activated region during intrinsic activation. However, cardiac resynchronization therapy (CRT) is most commonly applied by simultaneous LV and right ventricular (RV) pacing without contribution from intrinsic conduction. Therefore, targeting the LV lead to the latest activated region ...
Morris Daniel A DA Department of Cardiology, Charité University Hospital, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany, - - 2014
The aim of this study was to test the hypothesis that in patients with Fabry disease, 2D speckle-tracking echocardiography (2DSTE) could detect functional myocardial alterations such as left ventricular (LV), right ventricular (RV), and left atrial (LA) dysfunction, even when conventional cardiac measurements are normal. In addition, we hypothesized that ...
Borgeat K K Royal Veterinary College, Hatfield, UK; Highcroft Veterinary Referrals, Bristol, - - 2014
The use of cardiac biomarkers to assist in the diagnosis of occult and symptomatic hypertrophic cardiomyopathy (HCM) in cats has been established. There is limited data describing their prognostic utility in cats with HCM. Circulating concentrations of N-terminal B-type natriuretic peptide (NTproBNP) and cardiac troponin I (cTnI) predict cardiac death ...
Lenarczyk Radosław R From the Department of Cardiology, Congenital Heart Disease and Electrotherapy, Silesian Medical University, Silesian Centre for Heart Diseases, Zabrze, - - 2014
The prognostic impact of improvement in health-related quality of life (QoL) and its relation to response in cardiac resynchronization therapy (CRT) recipients remains unknown. To assess the correspondence between response to CRT and improvements in QoL and to verify if a change in QoL after pacing influences outcome in CRT ...
Rong Jie J Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, ‡State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, §Synthetic and Functional Biomolecules Center, and ∥Peking-Tsinghua Center for Life Sciences, Peking University , Beijing 100871, - - 2014
In the heart, glycosylation is involved in a variety of physiological and pathological processes. Cardiac glycosylation is dynamically regulated, which remains challenging to monitor in vivo. Here we describe a chemical approach for analyzing the dynamic cardiac glycome by metabolically labeling the cardiac glycans with azidosugars in living rats. The ...
Lee Justin M S - - 2014
Focal atrial tachycardias arise preferentially from specific locations within the atria. Careful analysis of the P wave can provide useful information about the chamber and likely site of origin within that chamber. Macro-reentrant atrial flutter also tends to occur over a limited number of potential circuits. In this case, the ...
Traykov Vassil B VB Clinic of Cardiology, Tokuda Hospital - Sofia, N.Vaptzarov blvd. 51B, 1407 Sofia, Bulgaria.. - - 2014
Determining the chamber of origin of focal atrial tachycardias (FATs) arising at or close to the septum might require biatrial mapping. This review focuses on the available tools and methods used to distinguish right atrial from left atrial origin before left atrial access is obtained. These include analysis of P ...
Taylor Colleen M - - 2014
Focal atrial tachycardias arising from the atrial appendages and the aortic sinuses of Valsalva are less frequently encountered in clinical practice. This review article describes the clinical presentation, surface P wave morphology, electrophysiologic characteristics and treatment of these arrhythmias. Catheter ablation of these focal tachycardias has a high success rate. ...
Kohári Mária - - 2014
Atrial tachycardias are common after open heart surgery. Most commonly these are macro-reentrant including cavotricuspid isthmus dependent atrial flutter, incisional right atrial flutter and left atrial flutter. Focal atrial tachycardias occur less frequently. The specific type of atrial tachycardia highly depends on the type of surgical incision. Catheter ablation can ...
Sághy László L 2nd Department of Internal Medicine and Cardiology Centre, University of Szeged, Korányi fasor 6. 6724 Szeged, Hungary.. - - 2014
One of the most important proarrhythmic complications after left atrial (LA) ablation is regular atrial tachycardia (AT) or flutter. Those tachycardias that occur after atrial fibrillation (AF) ablation can cause even more severe symptoms than those from the original arrhythmia prior to the index ablation procedure since they are often ...
Rosso Raphael R Tel-Aviv Sourasky Medical Center, Tel-Aviv, - - 2014
-The magnitude of QT-prolongation in response to bradycardia, rather than the bradycardia per-se, determines the risk for torsade-de-pointes (TdP) during atrio-ventricular block (AVB). However, we do not know why some patients develop more QT prolongation than others despite similar bradycardia. We hypothesized that in patients who develop significant QRS-vector changes ...
Fujiwara Shohei S Cardiovascular Division, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, - - 2014
Left ventricular (LV) dyssynchrony is a causal factor in LV dysfunction and thought to be associated with LV twisting motion. We tested whether three-dimensional speckle tracking (3DT) can be used to evaluate the relationship between LV twisting motion and dyssynchrony. We examined 25 patients with sick sinus syndrome who had ...
Guo Rong R Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, - - 2014
Objectives: This investigation explored the short-term prognostic value of pentraxin-3 (PTX3) levels in patients with non-ST-segment elevation myocardial infarction (NSTEMI) treated by percutaneous coronary intervention (PCI). Methods: We measured plasma levels of PTX3 and other biomarkers in 525 PCI-treated NSTEMI patients (mean age, 57.7 years; 328 males). The associations of ...
Fang Danhong - - 2014
To establish whether left ventricular(LV) pacing by mini-thoracotomy is a safe and feasible procedure, after failed transvenous cardiac resynchronization therapy(CRT), we described four cases of patients demonstrated congestive heart failure(CHF) who had transvenous LV lead implantation failures and underwent a mini-left-lateral thoracotomy and implantation of an epicardial LV lead. After ...
Devine W Patrick WP Roddenberry Center for Stem Cell Biology and Medicine, Gladstone Institute of Cardiovascular Disease, San Francisco, United - - 2014
Mammalian heart development requires precise allocation of cardiac progenitors. The existence of a multipotent progenitor for all anatomic and cellular components of the heart has been predicted but its identity and contribution to the two cardiac progenitor "fields" has remained undefined. Here we show, using clonal genetic fate mapping, that ...
Meedech Pradtana P Interdisciplinary Program of Physiology, Graduate School, Chulalongkorn University, Bangkok 10330, - - 2014
Recent publications demonstrated that rabbits with right ventricular hypertrophy (RVH) possess high sensitivity and specificity for drug-induced arrhythmias. However, the underlying mechanism has not been elucidated. This study aimed to evaluate RVH induced changes in cardiac remodeling especially the transmural dispersion of repolarization (TDR), epicardial monophasic action potentials (MAP), and ...
Zhang Youhua Y Department of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY, USA; Funding: This study was supported in part by the National Heart, Lung, and Blood Institute of the NIH under Award Number R01HL103671 (A.M.G.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Electronic address: - - 2014
Heart failure (HF) is associated with increased atrial fibrillation (AF) risk. Accumulating evidence suggests the presence of myocardial tissue hypothyroidism in HF, which may contribute to HF development. Our recent report demonstrated that hypothyroidism, like hyperthyroidism, leads to increased AF inducibility. This study was designed to investigate the effect of ...
Maeda Takuma T Department of Anesthesiology, National Cerebral and Cardiovascular Center, Osaka, Japan. Electronic address: - - 2014
The goal of this study was to compare cardiac output derived from the FloTrac/Vigileo™ system (COFT) with cardiac output measured by 3-dimensional transesophageal echocardiography (CO3D) in patients with severe heart failure undergoing cardiac resynchronization therapy. The impact of preoperative systemic vascular resistance index on the accuracy of the FloTrac/Vigileo™ system ...
Bauer Ralf R Department of Cardiology, Angiology, and Respiratory Medicine, University Hospital Heidelberg , Heidelberg , Germany - - 2014
Abstract Background: Transthyretin-related amyloidosis (ATTR) is characterized by a wide heterogeneity of genotypes and predominantly neurological and cardiac phenotypes. This study aims to characterize a cohort of patients with the rare transthyretin (TTR) Val20Ile (p.TTRVal40Ile) variant. Methods and results: This study comprises a single-center cohort of 59 individuals subsequently evaluated ...
Moss Arthur J AJ University of Rochester Medical Center, Rochester, NY - - 2014
A lot has transpired in our understanding of the inherited Long QT syndrome (LQTS) since the first description of a family with prolonged QT interval, deafness, and sudden death by Jervell and Lange-Nielsen in 1957(1) and a similar family reported in 1958 by Levine, et al.(2) Several children with LQTS ...
Hofmann N P NP Department of Cardiology, University of Heidelberg, Heidelberg, - - 2014
We sought to determine the ability of quantitative myocardial perfusion reserve index (MPRI) by cardiac magnetic resonance (CMR) and high-sensitive troponin T (hsTnT) for the prediction of cardiac allograft vasculopathy (CAV) and cardiac outcomes in heart transplant (HT) recipients. In 108 consecutive HT recipients (organ age 4.1 ± 4.7 years, 25 [23%] with ...
Flam Benjamin B Department of Anesthesiology and Intensive Care, Karolinska University Hospital, Solna, Stockholm, Sweden - - 2014
Pheochromocytoma classically displays a variety of rather benign symptoms, such as headache, palpitations, and sweating, although severe cardiac manifestations have been described. We report a case of pheochromocytoma-induced inverted takotsubo-like cardiomyopathy leading to shock and cardiac arrest successfully treated with extracorporeal membrane oxygenation (ECMO) as a bridge to pharmacological therapy ...
Eschalier Romain R Hôpital Cardiologique du Haut-Lévêque, CHU Bordeaux, Université Bordeaux, IHU LIRYC, Bordeaux, France; Clermont Université, Université d'Auvergne, Cardio Vascular Interventional Therapy and Imaging (CaVITI), Image Science for Interventional Techniques (ISIT), UMR6284, and CHU Clermont-Ferrand, Cardiology Department, F-63003 Clermont-Ferrand, - - 2014
Left Bundle Branch Block (LBBB) leads to prolonged left ventricular (LV) total activation time (TAT) and ventricular electrical uncoupling (VEU: mean LV activation time minus mean right ventricular (RV) activation time); both have been shown to be preferential targets for cardiac resynchronization therapy (CRT). Whether RV apical pacing (RVAP) produces ...
Ban Ji-Eun JE Division of Cardiology,Department of Internal Medicine,Korea University Medical Center,Seoul,Republic of - - 2014
A 31-year-old patient previously underwent a Mustard operation presented with palpitations. Atrial tachycardia and paroxysmal atrial fibrillation were documented on the surface electrocardiogram. Under the guidance of a three-dimensional electroanatomic mapping system, ablation of the isolated left-sided pulmonary vein and a cavo-tricuspid isthmus-dependent intra-atrial macro re-entry circuit eliminated atrial tachycardia ...
Hesselkilde Eva Z - - 2014
BackgroundDespite increased focus on cardiac arrhythmias in horses, the nature and prevalence is still poorly described. Case reports suggest that arrhythmias occurring secondary to systemic disease are seen more commonly in the clinic than arrhythmias caused by cardiac disease. The aim of this study was to investigate the prevalence of ...
Blustin Jodi M JM 1 Division of Cardiovascular Diseases, Gonda Vascular Center, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, - - 2014
The most feared consequence of atrial fibrillation (AF) is thromboembolism, either to the brain causing stroke or to the non-cerebral circulation. Valvular atrial fibrillation (VAF) and non-valvular atrial fibrillation (NVAF) differ not only by morphological substrate of arrhythmia but also by the rate of thromboembolic complications, predisposing factors and destination ...
Koenig Matthew A MA The Queen's Medical Center, Neuroscience Institute, 1301 Punchbowl Street, QET5, Honolulu, HI 96813, USA. Electronic address: - - 2014
Brain injury represents the major cause of long-term disability and mortality among patients resuscitated from cardiac arrest. Brain-directed therapies include maintenance of normal oxygenation, hemodynamic support to optimize cerebral perfusion, glycemic control, and targeted temperature management. Pertinent guidelines and recommendations are reviewed for brain-directed treatment. The latest clinical trial data ...
Matrone Gianfranco G 1 British Heart Foundation Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh , Edinburgh, United Kingdom - - 2014
Abstract Mammalian models of cardiac disease have provided unique and important insights into human disease but have become increasingly challenging to produce. The zebrafish could provide inexpensive high-throughput models of cardiac injury and repair. We used a highly targeted laser, synchronized to fire at specific phases of the cardiac cycle, ...
Travers S S Fire Brigade of Paris, Emergency medical department. Electronic address: - - 2014
Dispatcher-assisted cardiopulmonary resuscitation increases the likelihood of survival and thus is highly recommended. But the detection rate of out-of-hospital cardiac arrest (OHCA) is very different from one system to another, and early recognition of cardiac arrest in the dispatch centre remains challenging. The aim of this study was to assess ...
Liou Kevin K Department of Cardiology, Eastern Heart Clinic, Prince of Wales Hospital, Randwick, Sydney, - - 2014
Left atrial fibromuscular band is a rare congenital cardiac anomaly. We present a patient with an incidental finding of left atrial band on an intra-operative transesophageal echocardiogram and characterize its appearance on two-dimensional and three-dimensional echocardiograms.
Liu Cheng-Fang CF *Department of Physiology, Shanxi Medical University, Taiyuan, China; †Department of Biomedical Sciences, Mercer University School of Medicine, Savannah, GA; and ‡Department of Physiology, School of Basic Medicine Peking Union Medical College, Beijing, - - 2014
: Activating IK1 channels is considered to be a promising antiarrhythmic strategy. Zacopride has been identified as a selective IK1 channel agonist and can suppress triggered arrhythmias. Whether this drug also exerts a beneficial effect on cardiac remodeling is unknown, and the present study sought to address this question. Cardiac ...
Okamoto Emi E EE New York University School of Medicine, New York, New York, United States of - - 2014
Twenty to thirty percent of persons with Trypanosoma cruzi infection eventually develop cardiomyopathy. If an early indicator were to be identified and validated in longitudinal studies, this could enable treatment to be prioritized for those at highest risk. We evaluated cardiac and extracellular matrix remodeling markers across cardiac stages in ...
Yildiz Okan O Department of Pediatric Cardiovascular Surgery, Istanbul Mehmet Akif Ersoy Thoracic & Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey - - 2014
Myocardial bridging (MB) is a rare coronary anomaly in children which is typically associated with hypertrophic obstructive cardiomyopathy (HCM) or left ventricular hypertrophy. Hypertrophic obstructive cardiomyopathy is the leading cause of sudden cardiac death in young patients, and the association of myocardial ischemia with sudden death has been recognized in ...
Abu-Zeitone Abeer A Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York. Electronic address: - - 2014
In LQTS, β-blocker therapy is effective in reducing the risk of cardiac events (syncope, aborted cardiac arrest, sudden cardiac death). Limited studies have compared the efficacy of different β-blockers. The goal of this study was to compare the efficacy of different β-blockers in long QT syndrome (LQTS) and in genotype-positive patients ...
van Dijk Gaby Pons - - 2014
The exact prevalence and nature of cardiac involvement in facioscapulohumeral muscular dystrophy (FSHD) is unknown. Nevertheless, the current opinion is that symptomatic cardiac disease is rare. We performed a cardiac screening [electrocardiogram (ECG) and echocardiography in the event of ECG abnormalities] in 75 genetically confirmed, ambulant FSHD patients without cardiac ...
Angheloiu George O GO Cardiac MRI Center, Gerald McGinnis Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, PA, USA, - - 2014
'Septal bounce' is a pathognomonic sign of constrictive pericarditis (CP). The objectives of the study are to resolve the etiology of the septal bounce, to generate septal bounce-related diagnostic tools, and to prove that its presence is related to the mechanical interaction between the atrioventricular inflow and the inter-ventricular septum. ...
Zhao Xiaohan X The Key Laboratory of Experimental Teratology, Ministry of Education and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong 250012, - - 2014
CUL4A and CUL4B are closely related cullin family members and can each assemble a Cullin-RING E3 ligase complex (CRL) and participate in a variety of biological processes. While the CRLs formed by the two cullin members may have common targets, the two appeared to have very different consequences when mutated ...
Rong Xiao-Song XS Department of Cardiothoracic Surgery, Wuxi People's Hospital, Wuxi, - - 2014
: Cardiac c-kit+ cells isolated from cardiac explant-derived cells modestly improve cardiac functions after myocardial infarction; however, their full potential has not yet been realized. The present study was undertaken to determine the isolation and culture of c-kit+ cardiac stem cells (CSCs), and the roles of myocardial injection of CSCs ...
Stub Dion D Baker IDI Heart and Diabetes Research Institute; St Paul's Hospital Vancouver; Department of Intensive Care Alfred Hospital Commercial Road Melbourne, - - 2014
Many patients who suffer cardiac arrest do not respond to standard cardiopulmonary resuscitation. There is growing interest in utilizing veno-arterial extracorporeal membrane oxygenation assisted cardiopulmonary resuscitation (E-CPR) in the management of refractory cardiac arrest. We describe our preliminary experiences in establishing an E-CPR program for refractory cardiac arrest in Melbourne, ...
Gray Clint C Liggins Institute and Gravida: National Centre for Growth and Development, University of Auckland, New Zealand. Key terms: Developmental programming, miRNA, Cardiovascular disease, Maternal - - 2014
Maternal undernutrition is known to cause cardiac hypertrophy, elevated blood pressure (BP) and endothelial dysfunction in adult offspring. Maternal undernutrition may also lead to disturbances in growth hormone (GH) regulation in offspring. As GH plays a key role in cardiac development, we utilised a model of maternal undernutrition to examine ...
Backes Carl H CH Nationwide Children's Hospital, Columbus, - - 2014
Objectives: To characterize the frequency and attributability of death among patients who died within 30 days of their cardiac catheterization (30-day mortality). Background: 30-day post-procedure mortality is commonly used as a quality outcome metric in national cardiac catheterization registries. It is unclear if this parameter is sufficiently specific to meaningfully ...
1 2 3 4 5 6 7 8 9 10 >