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Ida Hanae H http://orcid.org/0000-0002-8705-7143 Department of Internal Medicine, Okinawa Chubu Hospital, Uruma City, Okinawa, - - 2014
Cases with thrombi in multiple cardiac chambers are rare. We report an extremely rare case in which thrombi were formed in all four cardiac chambers at the same time. A 55-year-old man presented with biventricular failure and liver dysfunction. A 12-lead ECG and an echocardiogram revealed an old anteroseptal myocardial ...
Trayanova Natalia A NA Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University Baltimore, MD, - - 2014
Under diseased conditions, remodeling of the cardiac tissue properties ("passive properties") takes place; these are aspects of electrophysiological behavior that are not associated with active ion transport across cell membranes. Remodeling of the passive electrophysiological properties most often results from structural remodeling, such as gap junction down-regulation and lateralization, fibrotic ...
Lee Seahyoung S Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do 210-701, Korea. - - 2014
Atrial fibrillation (AF) has been recognized as a major cause of cardiovascular-related morbidity and mortality. MicroRNAs (miRNAs) represent recent additions to the collection of biomolecules involved in arrhythmogenesis. Reactive oxygen species (ROS) have been independently linked to both AF and miRNA regulation. However, no attempts have been made to investigate ...
Molina O Gabriela G Department of Internal Medicine, Medstar Union Memorial Hospital, Baltimore, MD, USA; - - 2014
Introduction: Cardiac amyloidosis is the most common cause of infiltrative cardiomyopathy and is associated with a poor prognosis. Transthyretin cardiac amyloidosis, particularly the type caused by the mutation that replaces the amino acid valine with the amino acid isoleucine at position 122 (Val122Ile), is most common among African- Americans above ...
Grimm Wolfram W Department of Cardiology, University Hospital of Marburg and Gießen, Philipps-University Marburg, Marburg 35033, Germany. - - 2014
The relationship between heart failure (HF), sleep-disordered breathing and cardiac arrhythmias is complex and poorly understood. Whereas the frequency of predominantly obstructive sleep apnea in HF patients is low and similar or moderately higher to that observed in the general population, central sleep apnea (CSA) has been observed in approximately ...
van de Sande Danny A J P DA Department of Cardiology, Máxima Medical Center, De Run 4600, 5504 DB Veldhoven, The - - 2014
Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease with prevalence of 0.2% in the population. More than 1000 mutations in more than 10 genes encoding for proteins of the cardiac sarcomere have been identified. Cardiac magnetic resonance imaging (CMR) is used to characterize left ventricular morphology with great precision ...
Yang Meiying M Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States of - - 2014
Excess mitochondrial reactive oxygen species (mROS) play a vital role in cardiac ischemia reperfusion (IR) injury. P66Shc, a splice variant of the ShcA adaptor protein family, enhances mROS production by oxidizing reduced cytochrome c to yield H2O2. Ablation of p66Shc protects against IR injury, but it is unknown if and ...
Weidemann Frank - - 2014
Anderson-Fabry disease is an X-linked lysosomal storage disorder caused by alpha-galactosidase A deficiency. The intracellular storage of globotriaosylceramides in different tissues and organs leads to a multisystemic disease affecting kidneys, nervous system and the heart. Fabry cardiomyopathy is frequent and leads to concentric left-ventricular hypertrophy. Typical pattern in advanced stages ...
Wicks Eleanor C - - 2014
Arrhythmogenic right ventricular cardiomyopathy is an inherited cardiac muscle disease associated with sudden cardiac death, ventricular arrhythmias and cardiac failure. It is primarily a disease of the desmosome, with mutations in desmosomal protein genes identified in approximately 50% of affected individuals. Mutations result in fibrofatty replacement of cardiomyocytes, aneurysm formation ...
Rusu Cristian - - 2014
Cardiac Phase-resolved Blood-Oxygen-Level-Dependent (CP-BOLD) MRI examines changes in myocardial oxygenation in response to ischemia without contrast and stress agents. Since signal intensity changes are subtle, quantitative approaches are necessary to examine variations in myocardial BOLD signals and identify ischemic myocardial territories. Here, using data from animal studies, we extract myocardial ...
Giovanni Di Salvo - - 2014
Friedreich's ataxia (FA) is associated with progressive cardiac hypertrophy resulting from a genetic abnormality in the frataxin gene. Cardiac involvement is the most common cause of death (59%) in FA patients. Cardiac related death occurs at a significantly younger age than non-cardiac related death. Idebenone is a short-chain quinone analogue ...
Klein Michael J MJ Department of Surgery, State University of New York, Downstate Medical Center at Long Island College Hospital, Brooklyn, NY, USA - - 2014
Management of anemic patients refusing blood transfusion remains challenging. Concomitant coronary artery disease further complicates management. We sought to decrease the likelihood of cardiac events by employing hypothermia and neuromuscular blockade, in addition to limited phlebotomy, in a critically anemic Jehovah's Witness patient following emergent colectomy. The patient's hemoglobin concentrations ...
Razavi Moaven M Schneider Institutes for Health Policy, Heller School, Brandeis University, Waltham, Massachusetts, 02454-9110, United States of - - 2014
Medicare conducted a payment demonstration to evaluate the effectiveness of two intensive lifestyle modification programs in patients with symptomatic coronary artery disease: the Dr. Dean Ornish Program for Reversing Heart Disease (Ornish) and Cardiac Wellness Program of the Benson-Henry Mind Body Institute. This report describes the changes in cardiac risk ...
Dziewierz Artur - - 2013
ST-segment elevation myocardial infarction (STEMI) due to coronary artery occlusion in the setting of acute carbon monoxide (CO) poisoning is a very rare presentation. Our aim was to report on the use of primary angioplasty in a patient with STEMI in the setting of CO poisoning. A 36-year-old man with ...
Akilli Nazire Belgin - - 2013
Carbon monoxide (CO) poisoning frequently affects repolarization, resulting in abnormal electrocardiography findings. The goal of this study was to examine the effect of CO poisoning on the novel transmyocardial repolarization parameters T peak-T end (Tp-e), Tp-e dispersion, and Tp-e/QT and the relationship of these parameters to myocardial injury (MI). This ...
Chenniappan M - - 2013
The aVR is often neglected lead. It is an unipolar lead facing the right superior surface. As all the depolarisations are going away from lead aVR, all waves are negative in aVR (P, QRS, T) in normal sinus rhythm. In dextrocardia, (True and technical) the p is upright in aVR. ...
Kutarski Andrzej - - 2013
Abrasion of the outer insulation in crush syndrome and in the pocket region is a common cause of endocardial lead failure. Lead fracture at the level of the tricuspid valve has also been described. We examined 1,212 endocardial leads removed percutaneously from 700 patients. The average time the leads had ...
Chen Sammy Pl - - 2013
We report a case of acute poisoning in a 48-year-old man who presented with chest pain, abdominal pain, dizziness, sweatiness, blurred vision, and severe hypotension after ingestion of honey. His electrocardiogram showed sinus bradycardia and transient ST elevation. He made a good recovery after treatment with atropine and close monitoring. ...
Chang Hsin-An HA 1 Department of Psychiatry, Tri-Service General Hospital, Taipei, Taiwan, - - 2013
Altered cardiac autonomic function has been proposed in schizophrenia, but the results are mixed. Therefore, analyses with larger sample sizes and better methodology are needed. To examine whether acute schizophrenia is associated with cardiac autonomic dysfunction, 314 unmedicated patients with acute schizophrenia and 409 healthy volunteers, aged 18-65 years, were ...
Choi Kyu - - 2013
A 50-year-old man, who underwent a procedure for an implantable cardioverter defibrillator (ICD), visited the outpatient department of our clinic after suffering multiple ICD shocks. The ICD interrogation revealed recurrent shock due to a high frequency of noise that is sensed by the device as ventricular fibrillation. Chest radiography revealed ...
Ciftçi Ozgür - - 2013
Carbon monoxide (CO) poisoning is associated with direct cardiovascular toxicity. In mild CO poisoning in which cardiovascular life support is not required, the effects of CO on left and right ventricular functions are unknown in patients without cardiac failure. Echocardiography was used to determine whether or not mild CO poisoning ...
Alizadeh-Sani Zahra Z Rajaei Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR - - 2013
A 64-year-old female with history of previous aortoiliac occlusion and aortoiliac bypass operation four months ago presented with dyspnea, ascites and leg edema. She has been suffering from bloody diarrhea since two weeks earlier. Laboratory data showed important eosinophilia and stool examination was positive for Strongyloides stercoralis. Patient had clinical ...
Joshi P - - 2013
Organophosphorus compounds are used as pesticides and represent a common cause of poisoning in developing countries including India due to their widespread availability and use. Toxicity due to these agents can affect many organs including heart. Here, we report a case of acute organophosphorus poisoning (parathion), followed by acute myocardial ...
Hirakawa Akihiko - - 2013
Hydrogen sulfide is a toxic, colorless gas produced by decaying organic matter. Its toxic effects are due to blocking of cellular respiratory enzymes, leading to anoxia. We report a 28-year-old man who attempted suicide using hydrogen sulfide gas. When the emergency service arrived, his friend was dead and the patient ...
Ryoo Sm - - 2013
Introduction: Carbon monoxide (CO) is one of the leading causes of poisoning; it inhibits oxygen delivery, subsequently causing ischemic changes and ultimately death by multiorgan failure. Furthermore, thromboembolic episodes due to CO poisoning have been reported. However, intracardiac thrombus formation following exposure to CO has been very rarely described. Here, ...
Kutyifa Valentina - - 2013
The aim of the study was to evaluate the effi cacy and safety of small surface steroid-eluting atrial and ventricular pacing leads in comparison to non-steroid leads using remote monitoring system (Biotronik Home Monitoring®). In this randomized multicenter prospective trial, SIELLO T steroid-eluting ventricular leads (n = 42) were compared ...
Sato Daisuke D Department of Pharmacology, Genome Building (GBSF) University of California, Davis Davis, - - 2013
Cardiac alternans describes contraction of the ventricles in a strong-weak-strong-weak sequence at a constant pacing frequency. Clinically, alternans manifests as alternation of the T-wave on the ECG and predisposes individuals to arrhythmia and sudden cardiac death. In this review, we focus on the fundamental dynamical mechanisms of alternans and show ...
Najafi Atabak A Department of Anesthesiology & Critical care of Tehran University of Medical Science, Tehran, - - 2013
We report a 56-year-olds female with supraventricular arrhythmia due acute ischemic stroke without structural heart disease. A patient presented with sudden onset of lethargy, right hemiplegia, and global aphasia. There was previous history of stroke 1 year ago presented with left hemiplegia that recovered completely during 10 days. There was ...
Cheng Zhongwei - - 2012
BACKGROUND: To distinguish left ventricular outflow tract (LVOT) from right ventricular outflow tract (RVOT) origin in idiopathic premature ventricular contractions or ventricular tachycardia (PVCs/VT) patients with transitional lead at V3 is still a challenge. We sought to develop a new electrocardiography (ECG) algorithm for distinguishing LVOT from RVOT origin in ...
Karacağlar Emir E Department of Cardiology, Faculty of Medicine Hospital, Baskent University, Ankara, - - 2012
Left ventricular diverticulum is a rare congenital malformation consisting of a localized protrusion of the endocardium and myocardium from the free wall of the left ventricle (LV). The prevalence of the disease is 0.26% in nonselected patients who underwent cardiac catheterization. It is believed that the etiology is an intrinsic ...
Burcham Grant N - - 2012
Twenty-six 5-month-old Holstein calves were accidentally exposed to discarded branches of yew bushes (Taxus sp.). Several calves were found dead approximately 24 hr after exposure; however, a few calves died several days after exposure. One calf died 18 days after the initial exposure to Taxus sp. and was examined on ...
Salinas Pablo - - 2012
The no-reflow phenomenon (NRP) is defined as the lack of adequate myocardial tissue perfusion despite a patent epicardial coronary artery. The incidence of NRP varies between 2-5% of elective percutaneous coronary interventions (PCI) and 30% in primary PCI. Clinically, it is an independent predictor of myocardial infarction, in-hospital mortality, and ...
Vukcević Natasa Perković - - 2012
Caffeine is indicated in the treatment of migraine headaches, as well as neonatal apnea and bradycardia syndrome. In mild poisoning, the most prevalent symptoms are nausea, vomiting, diarrhea, tremor, anxiety and headache. In more severe cases, symptoms consist of heart rythym abnormalities, myocardial infarction and seizures. Due to its common ...
Greutmann Matthias - - 2012
AimsSupravalvar aortic stenosis is a rare form of left ventricular outflow tract obstruction that is often progressive in childhood. Little data are available on outcomes in the adult population. Our aim was to define cardiac outcomes in adults with supravalvar aortic stenosis.Methods and resultsThis is a multicentre retrospective study of ...
Osken A - - 2012
Mad honey poisoning which is induced by Grayanotoxin (Andromedotoxin), is also known to have adverse effects in the cardiovascular system leading to different clinical entities. This toxin is produced by a member of the Rhododendron genus of plants of two R. Luteum and R. Panticum. In this article, we presented ...
Thakar Saurabh - - 2012
Commotio cordis is a rare type of blunt cardiac injury in which low impact chest trauma causes sudden cardiac arrest, usually occurs from being struck by a projectile during sports. The most common arrhythmia during commotio cordis is ventricular fibrillation, although complete heart block and an idioventricular rhythm have also ...
Kolwicz Stephen C SC - - 2012
Decreased fatty acid oxidation (FAO) with increased reliance on glucose are hallmarks of metabolic remodeling that occurs in pathological cardiac hypertrophy and is associated with decreased myocardial energetics and impaired cardiac function. To date, it has not been tested whether prevention of the metabolic switch that occurs during the development ...
van der Veen Berlinda J - - 2012
Assessment of cardiac innervation using single-photon emission computer tomography (SPECT) is less established than planar imaging, but may be more suitable for quantification. Therefore, a volumetric quantification of I-123 MIBG SPECT acquisitions was performed. Reproducibility, the effects of extra cardiac I-123 MIBG uptake and the relation with conventional planar indices ...
Collier P - - 2012
The emergence of cardiac fibrosis (the prototypal myocardial interstitial disease) as an important adverse predictor of risk in heart disease is not surprising given that it is largely responsible for cardiac stiffness, provides a substrate for rhythm disturbances and promotes tissue hypoxia and development of heart failure. Yet, this diagnosis ...
Chin Alvin J - - 2012
To illustrate the impact developmental biology and genetics have already had on the clinical management of the million infants born worldwide each year with CHD, we have chosen three stories which have had particular relevance for pediatric cardiologists, cardiothoracic surgeons, cardiac anesthesiologists, and cardiac nurses. First, we show how Margaret ...
Kurosaka Satoshi - - 2012
Protein arginylation mediated by arginyltransferase (ATE1) is essential for heart formation during embryogenesis, however its cell-autonomous role in cardiomyocytes and the differentiated heart muscle has never been investigated. To address this question, we generated cardiac muscle-specific Ate1 knockout mice, in which Ate1 deletion was driven by α-myosin heavy chain promoter ...
Badawi Ramy A - - 2012
Percutaneous left ventricular assist device (pLVAD) utilization is increasing as the potential applications expand. We report a case of high-risk balloon aortic valvuloplasty and percutaneous coronary intervention using the Impella 2.5 pLVAD in a patient with severely depressed left ventricular function as a bridge to heart transplantation.
Heredero Angeles - - 2012
Background: Synchronization between the left ventricle and a left ventricular assist device (LVAD) may be important for ventricular unloading and coronary perfusion. We assessed the synchrony between cardiac and LVAD cycles by increasing delays in steps of 100 msec throughout the cycle, under conditions of total and partial left ventricular ...
Rubart Michael - - 2012
This article gives an overview of the 2011 Riley Heart Center Symposium that was held in Indianapolis, IN, USA, 11-13 September, 2011.
Senbanerjee Sucharita - - 2012
Abstract Prolyl Hydroxylases belong to the family of iron- and 2-oxoglutamate-dependent dioxygenase enzyme. Several, distinct prolyl hydroxylases have been identifed. The Hypoxia-Inducible Factor (HIF) prolyl hydroxylase termed Prolyl Hydroxylase domain enzymes (PHDs) play an important role in oxygen regulation in the physiological network. There are three isoforms that have been ...
Gomez Elodie - - 2012
Protein tyrosine phosphatase 1B (PTP1B) regulates tyrosine kinase receptor-mediated responses, and especially negatively influences insulin sensitivity, thus PTP1B inhibitors (PTP1Bi) are currently evaluated in the context of diabetes. We recently revealed another important target for PTP1Bi, consisting in endothelial protection. The present study was designed to test whether reduction of ...
Mahtab Edris A F - - 2012
OBJECTIVES: Borderline left ventricle is the left ventricular morphology at the favorable end of the hypoplastic left heart syndrome. In contrast to the severe end, it is suitable for biventricular repair. Wondering whether it is possible to identify cases suitable for biventricular repair from a developmental viewpoint, we investigated the ...
Luther Daniel J DJ Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH, - - 2012
We previously reported that type VI collagen deposition increases in the infarcted myocardium in vivo. To date, a specific role for this nonfibrillar collagen has not been explored in the setting of myocardial infarction (MI). To determine whether deletion of type VI collagen in an in vivo model of post-MI ...
Oliveira Sílvia Marta - - 2012
Left ventricular noncompaction is an unusual but increasingly recognized cardiomyopathy, the etiology of which is still not definitely established. Clinical presentation includes a wide spectrum of scenarios, including heart failure, thromboembolism and malignant arrhythmias, with half of deaths occurring suddenly. Early detection of LVNC is therefore essential to prevent sudden ...
Morgan Gareth John - - 2012
The use of combined fluoroscopic and echocardiographic imaging in congenital intervention is a well-established and developing concept. We report the case of a 1.2 kg, hemodynamically unstable neonate with tetralogy of Fallot, in whom we implanted a right ventricular outflow tract stent under primarily echocardiographic guidance. This represents the smallest reported ...
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