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- - 2014
The new oral anticoagulants are the way of the future when it comes to stroke prevention in atrial fibrillation (AF). The ROCKET-AF trial showed that not only was rivaroxaban non-inferior to warfarin for preventing stroke and systemic embolism, but safer too.
Bhoi Sanjeev S Department of Emergency Medicine, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, - - 2014
The continuing advances in the biochemical research for the discovering an ideal biomarker for diagnosing myocardial injury have led to discovery cardiac Troponin, a biochemical gold standard for myocardial necrosis. Further with advances in the immunoassay techniques, the 99th percentile cutoff value of cardiac troponin required for the diagnosis of ...
van Dijk Gaby Pons - - 2014
The exact prevalence and nature of cardiac involvement in facioscapulohumeral muscular dystrophy (FSHD) is unknown. Nevertheless, the current opinion is that symptomatic cardiac disease is rare. We performed a cardiac screening [electrocardiogram (ECG) and echocardiography in the event of ECG abnormalities] in 75 genetically confirmed, ambulant FSHD patients without cardiac ...
Salah Ahmed A Department of Cardiology, Second Xiangya Hospital Central South University; Changsha-China. - - 2014
In this study we assess the value of left atrial dyssynchrony time measured by tissue Doppler imaging (TDI) to predict recurrences after pulmonary vein isolation (PVI) in patients with paroxysmal and persistent atrial fibrillation (AF). One hundred sixty patients (57±7.5 years, 122 males) with symptomatic drug-refractory paroxysmal and persistent AF, ...
Saleh Akram Abdeljaber AA Akram Abdeljaber Saleh, Jordan University Hospital - Cardilogy,, Faculty of Medicine,, The University of Jordan,, Amman 1122, Jordan, T: +962795531085, - - 2014
Cefriaxone is a third-generation cephalosporin that might rarely cause a severe allergic reaction. Acute cardiac emergencies are quite rare in the setting of drug allergies. Here, we report the first case of myocardial infarction and AV-block after intravenous cefriaxone administration.
Chamsi-Pasha Hassan H King Fahd Armed Forces Hospital, - - 2014
The holy month of Ramadan is one of the five pillars of Islam. During this month, fasting Muslims refrain from eating, drinking, smoking, and sex from dawn until sunset. Although the Quran exempts sick people from the duty of fasting, it is not uncommon for many heart disease patients to ...
Assadian Rad Mohammad M Cardiovascular Research Center, Faculty of Medicine, Guilan University of Medical Sciences; Rasht-Iran. - - 2014
Cardiac resynchronization therapy (CRT) is introduced as a promising therapeutic option in heart failure (HF) patients with ventricular dyssynchrony.The challenge, however, is identifying the patients who are suitable candidates for this procedure. Fragmented QRS (fQRS) is associated with subendocardial fibrosis and myocardial scars. In this study, we aimed to evaluate ...
Koutsampasopoulos K K Cardiology Department, General Hospital of Halkidiki, Polygyros, Halkidiki, - - 2014
Carbamazepine, a widely used antiepileptic drug that has been used for the treatment of both partial and generalized seizures, for trigeminal neuralgia, as a mood stabilizer and for treatment of neuropathic pain syndromes, may have negative chronotropic and dromotropic effects on the cardiac conduction system. We report a case of ...
Duan Xu X Department of Cardiology, The First People's Hospital of Hangzhou, Hangzhou-China. - - 2014
Cardiac resynchronization therapy (CRT) was thought to have a proarrhythmic effect on ventricular repolarization. But the results of previous studies were inconsistent. The aim of this study was to determine the effect of CRT on ventricular repolarization. A meta-analysis of studies focused on the effect of CRT on ventricular repolarization ...
Garg Jalaj J 1Division of Cardiology, Department of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY; and 2Department of Internal Medicine, Mount Sinai Englewood Hospital and Medical Center Englewood, - - 2014
Acute carbon monoxide (CO) poisoning is the most common cause of poisoning and poisoning-related death in the United States. It manifests as broad spectrum of symptoms ranging from mild headache, nausea, and fatigue to dizziness, syncope, coma, seizures resulting in cardiovascular collapse, respiratory failure, and death. Cardiovascular complications of CO ...
Mehrpour Omid - - 2014
Abstract Aluminium phosphide (AlP) is a highly toxic pesticide that inhibits cytochrome oxidase c and causes oxidative stress. Death results from refractory cardiogenic shock due to myocardial dysfunction. There is very little information regarding extracorporeal life support in severe AlP poisoning. Although several therapies are available, none are curative. We ...
DragelytÄ— Gabija G Clinic of Anaesthesiology and Intensive Care, Centre of Toxicology, Faculty of Medicine, Vilnius University, Siltnamiu Street 29, LT-04130 Vilnius, - - 2014
We present the first case of severe cardiotoxicity of carbon monoxide leading to myocardial rupture and fatal outcome. 83-year-old woman was hospitalized 4 hours after the fire in her house with no respiratory or cardiac symptoms. After two days, she has suffered sudden collapse leading to cardiac arrest. Postmortem examination ...
Despa Sanda S Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY (S.D., S.S., F.D.) Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY (S.D., - - 2014
Chronic hypersecretion of the pancreatic hormone amylin is common in humans with obesity or prediabetic insulin resistance and induces amylin aggregation and proteotoxicity in the pancreas. We recently showed that hyperamylinemia also affects the cardiovascular system. Here, we investigated whether amylin aggregates interact directly with cardiac myocytes and whether controlling ...
Gialafos E E Department of Neurology, Athens National and Kapodistrian University, "Aeginition" Hospital, 11528 Athens, - - 2014
A 47-year-old female patient with multiple sclerosis (MS) developed symptomatic intermittent 2nd degree atrioventricular block (AVB) of five-hour duration, five hours after the first two doses of fingolimod, that resolved completely. Frequency domain analysis of heart rate variability (HRV) revealed increased parasympathetic activity and decreased sympathetic tone, while modified Ewing ...
Sayadi Omid O Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (O.S., D.P., N.I., R.D., - - 2014
This study investigates the hypothesis that morphologic analysis of intracardiac electrograms provides a sensitive approach to detect acute myocardial infarction or myocardial infarction-induced arrhythmia susceptibility. Large proportions of irreversible myocardial injury and fatal ventricular tachyarrhythmias occur in the first hour after coronary occlusion; therefore, early detection of acute myocardial infarction ...
Mujanovic Emir - - 2014
Left ventricular pseudoaneurysm is a rare condition because in most instances ventricular free-wall rupture leads to fatal pericardial tamponade. Rupture of the free wall of the left ventricle is a catastrophic complication of myocardial infarction, occurring in approximately 4% of patients with infarcts, resulting in immediate collapse of the patient ...
Ahmadi Zargham Hossein ZH Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
The intra-aortic balloon pump (IABP) is a mechanical device used to assist cardiac circulatory function in patients suffering from cardiogenic shock, congestive heart failure, refractory angina and complications of myocardial infarction. While using IABP in cardiac surgery is well established, there are few studies on the utility of IABP support ...
Padma Subramanyam S Department of Nuclear Medicine and PETCT, Amrita Institute of Medical Sciences, Cochin, Kerala, - - 2014
The increasing number of patients with coronary artery disease (CAD) undergoing major noncardiac surgery justifies guidelines concerning preoperative cardiac evaluation. This is compounded by increasing chances for a volatile perioperative period if the underlying cardiac problems are left uncorrected prior to major noncardiac surgeries. Preoperative cardiac evaluation requires the clinician ...
Wagner Robert R Department of Cardiovascular Anesthesiology, Centre of Cardiovascular and Transplant Surgery, Pekarska 53, 656 91 Brno, Czech Republic ; Department of Cardiovascular Diseases, International Clinical Research Center, St. Anne's University Hospital and Masaryk University, Pekarska 53, 656 91 Brno, Czech - - 2014
Cardiac surgery patients are now more risky in terms of age, comorbidities, and the need for complex procedures. It brings about reperfusion injury, which leads to dysfunction and/or loss of part of the myocardium. These groups of patients have a higher incidence of postoperative complications and mortality. One way of ...
Han L N LN First Department of Cardiovascular Internal Medicine in South Building, PLA General Hospital, Beijing, - - 2014
The aim of this study was to analyze the incidence and types of arrhythmia and their relationship with the severity and prognosis of chronic heart failure (CHF) in patients with dilated cardiomyopathy (DCM), and to investigate the therapeutic effect of torasemide versus furosemide on CHF and incidence of arrhythmia. DCM ...
Iwanaga Naoki N Department of Molecular Microbiology and Immunology, Nagasaki University School of Medicine, - - 2014
A 52-year-old Indian man was hospitalized due to dyspnea and a high fever caused by influenza A(H1N1)pdm2009. Elevated cardiac enzymes, a chest X-ray showing bilateral infiltrative shadows, cardiomegaly and pleural effusion and echocardiography indicating diffuse hypokinesis of the left ventricle suggested cardiac failure due to acute myocarditis. Owing to the ...
Lopez-Ruiz Nilson N http://orcid.org/0000-0001-5770-2773 Division of Cardiology, Hospital Pablo Tobon Uribe, Medellin, Antioquia, - - 2014
A 36-year-old woman who had received long-term treatment with chloroquine for systemic lupus erythematosus developed a third degree atrioventricular block and required a permanent pacemaker. Notably, left ventricular thickening and mild systolic dysfunction were noticed on echocardiography as well as on cardiac MRI. As there was no clear explanation for ...
Rao Meena P MP Cardiology Division, Duke University Hospital, 2301 Erwin Road, DUMC 3845, Durham, NC 27710, - - 2014
Atrial fibrillation is the most common arrhythmia and accounts for one-third of hospitalizations for rhythm disorders in the United States. The prevalence of atrial fibrillation averages 1% and increases with age. With the aging of the population, the number of patients with atrial fibrillation is expected to increase 150% by ...
Jafar Nagham Saeed NS 0000-0002-2773-6240 Department of Cardiology, Belhoul Speciality Hospital, P.O. Box 5527, Dubai, - - 2014
Cardiac sarcoidosis is a major cause of death in patients with systemic sarcoidosis. Cardiac manifestations are seen in 2.3% of the patients. Atrioventricular (AV) block is one of the common manifestations of cardiac sarcoidosis. Other presentations of cardiac involvement include congestive heart failure, ventricular arrhythmias, and sudden cardiac death. The ...
Frankish Kim - - 2014
Adults with congenital heart disease (CHD) frequently have cardiac arrhythmias, many of which are best treated with radiofrequency ablation (RFA). We present our experience in this group. Retrospective chart based review of diagnosis, arrhythmia type, results of cardiac electrophysiological assessment, and procedural and long-term clinical success of radiofrequency ablation. Forty-five ...
O'Kane Declan D Consultant Stroke and Acute Physician, Northampton General - - 2014
Left Atrial Ablation for Atrial Fibrillation is safe and effective for most patients. However a rare complication is thermal damage to the integrity of the normal physical barriers between the left atrium and the adjacent oesophagus due to the ablation process. This can lead to formation of an Atrial-Oesophageal fistula ...
Karam Myriam M Anesthesia and Critical care Department, University Hospital Notre Dame de Secours, St Charbel street, Byblos, - - 2014
A 78-year-old male patient presented with repetitive fainting episodes. His electrocardiogram showed sinus rhythm with persistent ventricular bigeminy. Concealed sinus node dysfunction (SND) with consecutive bradycardia-induced ventricular hyperexcitability was suspected. Pharmacological testing with atropine resulted in accelerated junctional rhythm along with nearly total disappearance of the ventricular ectopy. The diagnosis ...
Nakamura Shunichi S Division of Cardiology and Regenerative Medicine, Department of Internal Medicine, Nippon Medical School, Tokyo, - - 2014
Although B-type natriuretic peptide (BNP) and highly sensitive cardiac troponin T (cTnT) are useful for the evaluation of clinical features in various cardiovascular diseases, there are comparatively few data regarding the utility of these parameters in patients with hypertrophic obstructive cardiomyopathy (HOCM). The goal of this study was to assess ...
Zhang Wenbo W Departments of Medicine and Surgery, the Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, China; Critical Illness Research, Lawson Health Research Institute, London, Ontario, - - 2014
Myocardial contractile dysfunction in sepsis is associated with the increased morbidity and mortality. Although the underlying mechanisms of the cardiac depression have not been fully elucidated, an exaggerated inflammatory response is believed to be responsible. Nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome is an intracellular platform that ...
Shamsi Fahad F Department of Medicine, Aga Khan University Hospital, Karachi, Sind, - - 2014
Blunt thoracic trauma may result in cardiac injuries ranging from simple arrhythmias to fatal cardiac rupture. Coronary artery dissection culminating in acute myocardial infarction (AMI) is rare after blunt chest trauma. Here we report a case of a 37-year-old man who had an AMI secondary to coronary dissection resulting from ...
He Quan Q Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute, 6400 Sanger Road, Orlando, FL 32827, - - 2014
Tafazzin, a mitochondrial acyltransferase, plays an important role in cardiolipin side chain remodeling. Previous studies have shown that dysfunction of tafazzin reduces cardiolipin content, impairs mitochondrial function, and causes dilated cardiomyopathy in Barth syndrome. Reactive oxygen species (ROS) have been implicated in the development of cardiomyopathy and are also the ...
Dundon Benjamin K BK Cardiology Department, Royal Adelaide Hospital, Central Adelaide Local Health Network, Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia ; Monash Cardiovascular Research Centre, MonashHEART, Monash Health, Melbourne, Vic, Australia ; Central Northern Renal and Transplantation Service, Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, SA, - - 2014
Arteriovenous fistula-formation remains critical for the provision of hemodialysis in end-stage renal failure patients. Its creation results in a significant increase in cardiac output, with resultant alterations in cardiac stroke volume, systemic blood flow, and vascular resistance. The impact of fistula-formation on cardiac and vascular structure and function has not ...
Miller Douglas L DL Department of Radiology, University of Michigan Health System, 3240A Medical Sciences Building I, 1301 Catherine Street, Ann Arbor 48109-5667, - - 2014
High-intensity ultrasound pulses intermittently triggered from an ECG signal can interact with circulating contrast agent microbubbles to produce myocardial cavitation microlesions of potential therapeutic value. In this study, the timing of therapy pulses relative to the ECG R wave was investigated to identify the optimal time point for tissue reduction ...
Abdelghany Mahmoud - - 2014
Intravenous leiomyomatosis is a rare gynecologic disease that can be complicated with intracardiac involvement. All reported cases with cardiac extension involved the right cardiac chambers. Intracardiac leiomyoma may present with dyspnea, chest pain, palpitations, lower extremity swelling, or syncope. This is a unique case of a 40-year-old asymptomatic woman with ...
Tang W H Wilson WH Department of Cellular and Molecular Medicine, Center for Cardiovascular Diagnostics and Prevention, Lerner Research Institute, Cleveland, OH (W.T., S.L.H.) Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH (W.T., L.C., C.S., S.G.E., - - 2014
Few studies have investigated functional capacity self-assessment tools in either prediction of future major adverse cardiac outcomes beyond all-cause mortality or direct comparisons with clinically available biomarkers. We estimated functional capacity using the Duke Activity Status Index (DASI) questionnaire in 8987 sequential stable patients without acute coronary syndrome who were ...
Jivanji Salim Gm SG Department of Paediatric Cardiology, Royal Brompton Hospital, London, - - 2014
A newborn presenting with cyanosis at day 9 of life was admitted to the local hospital. Initial local echocardiography confirmed a cardiac issue and the patient was transferred to a tertiary cardiac hospital. Further imaging confirmed a rare presentation of cardiomyopathy with severe right ventricular outflow tract obstruction. Surgery was ...
Grall Sylvain S Université d'Angers, Laboratoire "Cardioprotection, Remodelage et Thrombose" , Angers , France ; Centre Hospitalier Universitaire d'Angers, Service de Cardiologie , Angers , - - 2014
Late gadolinium enhancement (LGE) on cardiac MRI (CMR) has been described as an independent predictive factor of cardiovascular events among patients with hypertrophic cardiomyopathy (HCM). LGE and Q waves are considered as myocardial scar markers but their relation in the context of HCM is poorly established and has to be ...
Dalla Vecchia Laura L IRCCS Fondazione Salvatore Maugeri, Istituto Scientifico di Milano , Milan , - - 2014
Strenuous exercise variably modifies cardiovascular function. Only few data are available on intermediate levels of effort. We therefore planned a study in order to address the hypothesis that a half marathon distance would result in transient changes of cardiac mechanics, neural regulation and biochemical profile suggestive of a complex, integrated ...
Pandit Anil A Division of Cardiovascular Diseases , Mayo Clinic , Scottsdale, Arizona , - - 2014
To determine the association between serum vitamin D level and left ventricular (LV) diastolic dysfunction. Vitamin D deficiency has been shown in observational and prospective studies to be associated with cardiovascular diseases including coronary artery disease, LV hypertrophy and systolic heart failure. Even though diastolic LV dysfunction is an early ...
Hajje Georges G Laboratoire de Recherche en Physiologie et Physiopathologie, Faculté de Médecine, Pôle Technologie Santé, Université Saint Joseph, Beirut, - - 2014
The cardiovascular effects of mild and overt thyroid disease include a vast array of pathological changes. As well, thyroid replacement therapy has been suggested for preserving cardiac function. However, the influence of thyroid hormones on cardiac remodeling has not been thoroughly investigated at the molecular and cellular levels. The purpose ...
Zhou Zhi-Wen ZW Department of Cardiology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China; Department of Cardiology, Shanghai Xuhui Central Hospital, Shanghai, People's Republic of - - 2014
We evaluated the acute impact of different cardiac pacing sites on two-dimensional speckle-tracking echocardiography (STE) derived left ventricular (LV) rotation and twist in healthy dogs. Twelve dogs were used in this study. The steerable pacing electrodes were positioned into right heart through the superior or inferior vena cava, into LV ...
Kriener Marcelo - - 2014
To investigate possible associations between the presence of craniofacial pain of cardiac origin and the location of cardiac ischemia and conventional risk factors. A total of 326 consecutive patients with confirmed myocardial ischemia (192 males, 134 females, mean age 64 years) were studied. Demographic details, health history, factors, prodromal symptoms, ...
Karaagac Kemal K Department of Cardiology, Bursa Yuksek Ihtisas Education and Research Hospital Bursa, - - 2014
Coronary artery ectasia (CAE) is commonly defined as local or generalized dilatation of a coronary vessel up to 1.5 times the diameter of an adjacent vessel. Tp-Te interval and Tp-Te/QT ratio have emerged as novel electrocardiographic markers of increased dispersion of ventricular repolarization. The aim of this study was to ...
Sudhakaran Sivakumar S Department of Medicine, Texas A&M University Health Science Center, College Station, - - 2014
Background Prolonged ventricular asystole is a rare vagal reaction caused by hydrocodone use. Sinus bradycardia is a characteristic presentation of the vasovagal response; examples of other presentations include arrest or atrioventricular block. Physicians need to be aware of ventricular asystole due to vagally-mediated atrioventricular block caused by hydrocodone or other ...
Kornhall Daniel Kristoffer DK Department of Anaesthesiology, University Hospital of North Norway, Sykehusveien 38, Tromsoe, 9038 - - 2014
Since the popularisation of closed chest cardiac compressions in the 1960s, open chest compressions in non-traumatic cardiac arrest have become a largely forgotten art. Today, open chest compressions are only rarely performed outside operating theatres. Early defibrillation and high quality closed chest compressions is the dominating gold standard for the ...
Janssen Rob R Department of Physiology, VU University Medical Center, Institute for Cardiovascular Research , Amsterdam , - - 2014
Cardiomyocyte size in the healthy heart is in part determined by the level of circulating thyroid hormone (TH). Higher levels of TH induce ventricular hypertrophy, primarily in response to an increase in hemodynamic load. Normal cardiac function is maintained in this form of hypertrophy, whereas progressive contractile dysfunction is a ...
Zhang Xingyu X Department of Anatomy with Radiology, University of Auckland, Auckland, New - - 2014
Myocardial infarction leads to changes in the geometry (remodeling) of the left ventricle (LV) of the heart. The degree and type of remodeling provides important diagnostic information for the therapeutic management of ischemic heart disease. In this paper, we present a novel analysis framework for characterizing remodeling after myocardial infarction, ...
Kornej Jelena J University of Leipzig, Heart Center, Department of Electrophysiology, Leipzig, Germany; University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, United - - 2014
Catheter ablation (CA) of atrial fibrillation (AF) is associated with inflammatory response, endothelial damage and with increased risk of thrombosis. However, whether these processes differ in peripheral and cardiac circulation is unknown. Plasma markers (von Willebrand factor (vWf), soluble P-selectin (sPsel) and interleukin-6 (IL-6)) were measured by ELISA at three ...
Rossi Stefano S Department of Life Sciences, University of Parma, Parma, Italy; CERT, Center of Excellence for Toxicological Research, INAIL, ex ISPESL, University of Parma, Parma, - - 2014
Advanced age alone appears to be a risk factor for increased susceptibility to cardiac arrhythmias. We previously observed in the aged rat heart that sinus rhythm ventricular activation is delayed and characterized by abnormal epicardial patterns although conduction velocity is normal. While these findings relate to an advanced stage of ...
Pavo Noemi N Department of Cardiology, Medical University of Vienna, Vienna, - - 2014
We compared the accuracy of NOGA endocardial mapping for delineating transmural and non-transmural infarction to the results of cardiac magnetic resonance imaging (cMRI) with late gadolinium enhancement (LE) for guiding intramyocardial reparative substance delivery using data from experimental myocardial infarction studies. Sixty domestic pigs underwent diagnostic NOGA endocardial mapping and ...
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