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Shi Zhiyong Z Department of Cardiothoracic Surgery, China Pingmei Shenma Medical Group General Hospital, Pingdingshan Kuanggong Road 1#, Henan, China, - - 2014
To investigate the effects of nuclear factor-κB activation inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) on cardiac ischemia reperfusion injury in a transplantation model. Hearts of C57BL/6 mice were flushed and stored in cold Bretschneider solution for 8 h and then transplanted into syngeneic recipient. Some mice were administrated intraperitoneally with DHMEQ (8 mg/kg) 1 h before ...
Deux Jean-François JF Radiology Department, Henri Mondor Hospital, University Paris Est Créteil, Assistance Publique-Hôpitaux de Paris , Créteil , France - - 2014
Abstract Background: Most of the studies that described cardiac amyloidosis using cardiac magnetic resonance (CMR) imaging refer to patients with primary light chain (AL) amyloidosis. The goal of this study was to evaluate cardiac involvement in patients with hereditary transthyretin associated (ATTR) amyloidosis and asymptomatic carriers and its relationships with ...
Kirk Jonathan J Johns Hopkins University, Medicine , 858 Ross Building , 720 Rutland Ave. , Baltimore, Maryland, United States, 21205 , 410-614-0024 ; - - 2014
While great strides have been made to improve the poor prognosis with cardiac disease, heart failure in particular, cardiac affections still remain the most prevalent, difficult to treat, and costly human pathologies in the western world. At rest, the heart produces a significant oxidative environment inside diverse cell compartments, due ...
De Ponti Roberto R aDepartment of Cardiology bDepartment of Radiology, Ospedale di Circolo-University of Insubria, Varese, - - 2014
Agenesia of the left atrial appendage in a patient with atrial fibrillation is shown. Although of interest, the prevalence of this abnormality is very low.
Rinaldi Christopher Aldo CA Cardiac Department, Guy's and St Thomas' Hospitals, London SE1 7EH, UK - - 2014
Non-response to cardiac resynchronization therapy remains a significant problem in up to 30% of patients. Multisite stimulation has emerged as a way of potentially overcoming non-response. This may be achieved by the use of multiple leads placed within the coronary sinus and its tributaries (dual-vein pacing) or more recently by ...
Nicolau-Raducu R R Departments of Anesthesiology, Ochsner Clinic Foundation, 1514 Jefferson Hwy, New Orleans, Louisiana, - - 2014
Current American College of Cardiology/American Heart Association guidelines caution that preoperative non-invasive cardiac tests may have poor predictive values in detecting coronary artery disease in liver transplant candidates. The purpose of our study was to evaluate the role of clinical predictor variables for early and late cardiac morbidity and mortality ...
Wildi Karin K Department of Cardiology, University Hospital Basel, Switzerland; Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, - - 2014
Cardiac troponins (cTn) I and T are organ-specific, but not disease specific biomarkers. Although acute myocardial infarction (AMI) is the most important cause of cTn elevation, other cardiac disorders as well as primarily noncardiac disorders with cardiac involvement often are also associated with cardiomyocyte injury. Levels of cTn should be ...
Bessem B B Center for Sports Medicine, University Medical Center Groningen, Groningen, The - - 2014
Sudden cardiac death in young athletes is a devastating event. The screening and detection of potentially life-threatening cardiac pathology by ECG is difficult due to high numbers of false-positive results, especially in the very young. The Seattle ECG criteria (2013) were introduced to decrease false-positive results. We compared the Seattle ...
Stec Sebastian S Department of Electroradiology, Institute of Nursing and Health Sciences, University of Rzeszow, Rzeszow, - - 2014
Objectives: The purpose of this study was to prospectively evaluate the feasibility and diagnostic value of right ventricular overdrive pacing (RVOP) during supraventricular tachycardia (SVT) using a 2-catheter approach with automatic pacing from the right ventricular inflow (RVIT) and outflow tract (RVOT). Methods: One hundred and thirty-six consecutive patients (with ...
Leyva Francisco F Centre for Cardiovascular Sciences, Queen Elizabeth Hospital, University of Birmingham, Edgbaston, Birmingham, United Kingdom. Electronic address: - - 2014
Cardiac resynchronization therapy (CRT) is an accepted treatment for patients with heart failure (HF), impaired left ventricular (LV) function, and a wide QRS complex. It has been revolutionary for patients with advanced HF whose only previous option was cardiac transplantation, and it is now a realistic option for patients with ...
Thum Thomas T Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, - - 2014
Cardiac stress leads to remodelling of cardiac tissue, which often progresses to heart failure and death. Part of the remodelling process is the formation of fibrotic tissue, which is caused by exaggerated activity of cardiac fibroblasts leading to excessive extracellular matrix production within the myocardium. Noncoding RNAs (ncRNAs) are a ...
Enriquez Andres A Division of Cardiology, Queen's University, Kingston, Ontario, - - 2014
Interatrial conduction disorders are frequent in patients with structural heart diseases, including hypertension, coronary disease, and hypertrophic cardiomyopathy, and they are strongly associated with atrial tachyarrhythmias, especially atrial fibrillation and flutter. Conduction delays lead to dispersion of refractory periods and participate in initiating and maintaining reentry circuits, facilitating atrial arrhythmias. ...
Oehler Andrew A Internal Medicine Department, Oregon Health and Science University, Portland, - - 2014
For proper distribution of preventative resources, a more robust method of cardiac risk stratification should be encouraged in addition to merely reduced ejection fraction. To this end, the QRS-T angle, an electrocardiogram-derived measure of the difference in mean vectors of depolarization and repolarization, has been found associated with sudden cardiac ...
Ho-Mouye Fabien F Radiology Department,CHU Felix Guyon Allée des Topazes,Reunion - - 2014
Asymptomatic isolated congenital left ventricular diverticulum: a cardiac MRI report about a 19-year-old man.
Franco Eduardo E Cardiovascular Institute, Hospital Clínico San Carlos, Madrid, - - 2014
Current clinical guidelines for ST-segment elevation myocardial infarction (STEMI) suggest prehospital activation of the cardiac catheterization team. In previous protocols in our center activation occurred once patients arrived at the hospital. In January 2011, we initiated a new primary angioplasty activation protocol from prehospital locations. Our objective was to quantify ...
Tsutsumi Yasuo M - - 2014
BackgroundExendin-4, an exogenous glucagon-like peptide-1 receptor (GLP-1R) agonist, protects the heart from ischemia/reperfusion injury. However, the mechanisms for this protection are poorly understood. Caveolae, sarcolemmal invaginations, and caveolins, scaffolding proteins in caveolae, localize molecules involved in cardiac protection. We tested the hypothesis that caveolae and caveolins are essential for exendin-4 ...
Liang Xingqun X Key Laboratory of Arrhythmia, Ministry of Education, East Hospital, Tongji University School of Medicine, Shanghai, China; Department of Medicine, University of California, San Diego, San Diego, - - 2014
Specialized myocytes of the cardiac conduction system (CCS) are essential to coordinate sequential contraction of cardiac atria and ventricles. Anomalies of the CCS can result in lethal cardiac arrhythmias, including sick sinus syndrome and atrial or ventricular fibrillation. To develop future therapies and regenerative medicine aimed at cardiac arrhythmias, it ...
Tschöpe Carsten C Department of Cardiology and Pneumology, Charité, University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany, - - 2014
Recently, a new paradigm for the development of heart failure with preserved ejection fraction (HFpEF) has been proposed, which identifies a systemic pro-inflammatory state induced by comorbidities as the origin of microvascular endothelial cell inflammation and subsequent concentric cardiac remodeling and dysfunction. This review further discusses the pivotal role of ...
Sakamoto Shun-Ichiro SI Department of Cardiovascular Surgery, Nippon Medical School, Tokyo, Japan. Electronic address: - - 2014
Ganglionated plexi ablation during atrial fibrillation surgery is not technically standardized for precise ganglionated plexi locations or ablation sequence. We aimed to identify precise active ganglionated plexi locations in patients with structural heart disease and explore the feasibility of anatomic ganglionated plexi ablation without prior mapping in patients with atrial ...
Kaye Gerald C GC Department of Cardiology, The University of Queensland and Princess Alexandra Hospital, Ipswich Road, Wolloongabba, Brisbane 4102, Queensland, Australia - - 2014
Chronic right ventricle (RV) apical (RVA) pacing is standard treatment for an atrioventricular (AV) block but may be deleterious to left ventricle (LV) systolic function. Previous clinical studies of non-apical pacing have produced conflicting results. The aim of this randomized, prospective, international, multicentre trial was to compare change in LV ...
Guinot Pierre Grégoire PG From the Anaesthesiology and Critical Care Medicine Department, Amiens University Hospital, Place Victor Pauchet, Amiens (P-GG,HD, OAA), Department of Anaesthesia and Intensive Care, Hôpital Bichat-Claude Bernard, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot and Unité INSERM U698, Paris (DL), and INSERM U1088, University of Picardy Jules Verne, Amiens, France - - 2014
Several authors have suggested that right ventricular dysfunction (RVd) may contribute to renal dysfunction in nonsurgical patients. We tested the hypothesis that RVd diagnosed immediately after cardiac surgery may be associated with subsequent development of renal dysfunction and tried to identify the possible mechanisms. A single-centre, prospective observational study. Amiens ...
Tsujikawa Masahiro M Department of Rehabilitation Medicine, Keio University School of Medicine, , - - 2014
Objective: To evaluate cardiac function using echocardiography in patients with stroke admitted to subacute rehabilitation units. Design: Retrospective, cross-sectional study. Participants: A total of 750 consecutive patients with stroke who were admitted to a suburban rehabilitation hospital. Mean age 67.5 years (standard deviation (SD) 12.3 years). Mean time since stroke ...
Mafi Rad Masih M Department of Cardiology, Maastricht University Medical Center, P. Debeyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands - - 2014
Left ventricular (LV) lead placement in the latest activated region is an important determinant of response to cardiac resynchronization therapy (CRT). We investigated the feasibility of coronary venous electroanatomic mapping (EAM) to guide LV lead placement to the latest activated region. Twenty-five consecutive CRT candidates with left bundle-branch block underwent ...
Barbhaiya Chirag C Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, - - 2014
Entrainment can be useful for mapping atrial tachycardias (AT) after atrial fibrillation (AF) ablation but may result in AT alteration or termination. We aimed to determine the incidence and risk factors for AT alteration or termination. In 30 consecutive patients, 62 ATs (mean CL 268±53 ms) in which overdrive pacing ...
Aguilar Cristian C Department of Pathology, Edgardo Rebagliati Hospital, Lima, Peru. Electronic address: - - 2014
Primary cardiac neoplasms are rare. However, among them, cardiac myxoma is the most common tumor. In contrast, primary cardiac lymphoma within a cardiac myxoma is extremely rare and might be difficult to diagnose because of non-specific clinical manifestations. We report the case of a previously healthy 52-year-old man who presented ...
Desimone Christopher V CV Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, - - 2014
Intra-ardiac echocardiography (ICE) offers a real-time assessment of cardiac structures to help guide intracardial maneuverability and placement of catheters and optimize sheath positioning, monitor for complications such as cardiac tamponade or valvular damage, and to assess for coagulum formation during ablation. The utility of ICE for left atrial appendage (LAA) ...
Du You-You YY Zhengzhou University. - - 2014
Chronic right ventricular apex (RVA) pacing can induce negative clinical effects. The aim of the present study was to compare RVA pacing with para-right bundle branch (para-RBB) pacing in terms of electrocardiogram and echocardiographic features. 41 consecutive persistent atrial fibrillation patients with an indication for permanent pacing treatment because of ...
Dankner Rachel R Unit for Cardiovascular Epidemiology, the Gertner Institute for Epidemiology and Health Policy Research, Sheba Medical Center, Tel Hashomer, Israel Division of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel - - 2014
Cardiac rehabilitation programs are greatly underutilized. This study was a multicenter interventional controlled cohort study. From cardiothoracic departments of five medical centers, 520 coronary artery bypass graft (CABG) patients (386 men) were enrolled in the control arm and 504 CABG patients (394 men) in the intervention arm of our study. ...
Zhou Jizi J Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China (J.Z., Yu.Z., Q.Z., Yi.Z., X.L., Y.Y.); Children's Hospital, Fudan University, Shanghai, China (Y.G., C.C., C.Z.); and Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, China - - 2014
In most cases, the clinical importance of fetal isolated mild tricuspid valve regurgitation is not known. This study evaluated the relationship between fetal isolated mild tricuspid regurgitation in the general obstetric population and postnatal congenital cardiac disorders. Detailed fetal echocardiography was done between 18 and 24 weeks' gestation to detect ...
Plourde Benoit B Department of Medicine, Faculty of Medicine, Quebec City, QC, - - 2014
For individuals and the society as a whole, the increased risk of sudden cardiac death in obese patients is becoming a major challenge, especially since obesity prevalence has been increasing steadily around the globe. Traditional risk factors and obesity often coexist. Hypertension, diabetes, obstructive sleep apnea and metabolic syndrome are ...
Yu Cheuk-Man CM Division of Cardiology, Department of Medicine and Therapeutics; Institute of Vascular Medicine; Institute of Innovative Medicine; Heart Education and Research Training (HEART) Center; and Li Ka Shing Institute of Health Sciences; Prince of Wales Hospital, The Chinese University of Hong Kong, Hong - - 2014
We report the results of long-term follow-up of the Pacing to Avoid Cardiac Enlargement (PACE) trial, a prospective, double-blinded, randomized, multicentre study that confirmed the superiority of biventricular (BiV) pacing compared with right ventricular apical (RVA) pacing in prevention of LV adverse remodelling and deterioration of systolic function at 1 ...
Ahmed Khurshid K Binawaluya Cardiac Center, 13750 Jakarta, - - 2014
Ideal positioning of left ventricular (LV) pacing lead in cardiac resynchronization therapy (CRT) is technically demanding. This case aims to place LV lead in anterolateral branch of coronary sinus (CS) using collateral route blindly. Externalization via the CS ostium using collaterals retrogrogradely, which was not visible in initial balloon occlusion ...
Weerasooriya Rukshen R University of Western Australia, Crawley, Royal Perth Hospital, Perth, Hollywood Private Hospital, Nedlands, Western Australia, Australia. Electronic address: - - 2014
Catheter ablation of atrial fibrillation (AF) is now one of the most frequently performed ablation procedures, but there are currently 2 important challenges: achieving permanent/durable rather than transient pulmonary vein isolation (PVI) and improving the results of ablation for the wider patient population with persistent AF. Recent technical advances in ...
Ozturk Cengiz C Department of Cardiology, Eskisehir Military Hospital, Eskisehir, - - 2014
Ozturk C, Aparci M, Cakmak T, Metin S, Balta S, Sen A. Atrial fibrillation presented with syncope in a jet pilot during daily briefing on squadron. Aviat Space Environ Med 2014; 85:965-9. Syncope may be the initial clinical presentation of atrial fibrillation (AF) and has a great potential for incapacitation ...
Hamirani Yasmin S YS Cardiovascular Division, Department of Medicine, University of Virginia Health System, Charlottesville, - - 2014
The goal of this systematic analysis is to provide a comprehensive review of the current cardiac magnetic resonance data on microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH). Data related to the association of MVO and IMH in patients with acute myocardial infarction (MI) with left ventricular (LV) function, volumes, adverse ...
van Kranenburg Matthijs M Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Radiology, Erasmus Medical Center, Rotterdam, the - - 2014
The aim of this study was to evaluate the value of microvascular obstruction (MO) and infarct size as a percentage of left ventricular mass (IS%LV), as measured by contrast-enhanced cardiac magnetic resonance, in predicting major cardiovascular adverse events (MACE) at 2 years in patients with ST-segment elevation myocardial infarction reperfused by ...
Brown Armand O AO Dept. of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of - - 2014
Hospitalization of the elderly for invasive pneumococcal disease is frequently accompanied by the occurrence of an adverse cardiac event; these are primarily new or worsened heart failure and cardiac arrhythmia. Herein, we describe previously unrecognized microscopic lesions (microlesions) formed within the myocardium of mice, rhesus macaques, and humans during bacteremic ...
Fox H H Department of Cardiology, Heart and Diabetes Center North Rhine, Westphalia, Ruhr University Bochum, Bad Oeynhausen, - - 2014
Sleep-disordered breathing (SDB), especially central sleep apnea with Cheyne-Stokes respiration (CSA-CSR), is highly prevalent in patients with severe heart failure (HF). SDB, and predominantly CSR, may improve after recovery of cardiac function, but available data are limited and inconclusive, particularly in patients who have undergone heart transplantation (HTX). The case ...
Dorbala Sharmila S Noninvasive Cardiovascular Imaging Program, Heart and Vascular Center, Department of Radiology; Department of Medicine (Cardiology), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address: - - 2014
Myocardial perfusion imaging (MPI) with PET has expanded significantly over the past decade. With the wider availability of PET scanners and the routine use of quantitative blood flow imaging, the clinical use of PET MPI is expected to increase further. PET MPI is a powerful tool to identify risk, to ...
Birnbaum Yochai Y The Section of Cardiology, The Department of Medicine, Baylor College of Medicine, Houston, TX, - - 2014
The electrocardiogram (ECG) is the most widely used imaging tool helping in diagnosis and initial management of patients presenting with symptoms compatible with acute coronary syndrome. Acute ischemia affects the configuration of the QRS complexes, the ST segments and the T waves. The ECG should be read along with the ...
Singh D - - 2014
We discuss two cases of incessant atrial tachycardia (AT), including the presentation and clinical course. It is important to differentiate AT from other causes of supraventricular tachycardia, such as atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular reentrant tachycardia (AVRT), as it would have implications on clinical management. Electrocardiographic features of ...
Suh Jong Hui JH 1 Department of Thoracic and Cardiovascular Surgery, Incheon St. Mary's Hospital, 2 Department of Thoracic and Cardiovascular Surgery, Daejeon St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of - - 2014
Calcified amorphous tumor (CAT) of the heart is an extremely rare cardiac mass. We describe a case of cardiac CAT in a 70-year-old Korean female who presented with acute onset dysarthria and right side weakness. Echocardiography and chest computed tomography revealed a left atrial mass that originated from the interatrial ...
Lewandowski PaweĊ‚ P Students' Scientific Society, Department of Anaesthesiology, Reanimation, Intensive Therapy, and Acute Poisonings, Pomeranian Medical University in Szczecin, Poland. - - 2014
Severe subarachnoid haemorrhage (SAH) is a common cause of cardiac arrest. The survival of patients with out-of-hospital cardiac arrest (OHCA) due to SAH is extremely poor. Electrocardiographic and echocardiographic changes associated with SAH may mimic changes caused by acute coronary syndromes (ACS) and thus lead to delayed treatment of the ...
Mir Arshid A Department of Pediatrics, Division of Cardiology, Oklahoma University Children Hospital, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, - - 2014
Rhabdomyoma, a benign hamartomatous tumor of the cardiac embryonic myocyte, is the most common intrauterine cardiac tumor and accounts for 0.12% of prenatal fetal studies. Fetal cardiac rhabdomyomas increase in size during second and early third trimester and spontaneously regress postnatally. The clinical presentation is usually benign, however, compromise of ...
Gawthrope Ian C IC Fremantle Hospital and Health Service, Fremantle Hyperbaric Unit, Alma Street, PO Box 480, Western Australia Phone: +61-(08)-9431-2233, E-mail: - - 2014
The adverse effects of hyperbaric oxygen (HBO) on cardiac physiology are considered a potential hazard during the treatment of some patients. The haemodynamic effects of HBO are poorly understood and the incompatibility of electrical equipment inside the chamber has made assessment difficult. At Fremantle Hyperbaric Unit, we have modified an ...
Sajeev Chakanalil Govindan CG Department of Cardiology, Government Medical College, Kozhikode, Kerala, - - 2014
We report a case of young male referred for evaluation of recent onset recurrent syncope. Inhospital electrocardiogram revealed an episode of ventricular flutter which reverted spontaneously to sinus rhythm. Transthoracic echocardiogram showed hyperechoic mass in the left ventricle. For further tissue characterization a cardiac magnetic resonance imaging was done which ...
Oliveira Marcos Aurélio Barboza de MA Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, - - 2014
The entry of sodium and calcium play a key effect on myocyte subjected to cardiac arrest by hyperkalemia. They cause cell swelling, acidosis, consumption of adenosine triphosphate and trigger programmed cell death. Cardiac arrest caused by hypocalcemia maintains intracellular adenosine triphosphate levels, improves diastolic performance and reduces oxygen consumption, which ...
Ferrari Andrés Di Leoni AD São Lucas Hospital, Catholic University of Rio Grande do Sul, Porto Alegre, RS, - - 2014
Implantable cardiac pacing systems are a safe and effective treatment for symptomatic irreversible bradycardia. Under the proper indications, cardiac pacing might bring significant clinical benefit. Evidences from literature state that the action of the artificial pacing system, mainly when the ventricular lead is located at the apex of the right ...
Suarez Gabriela G 1 Department of Internal Medicine, 2 Department of Cardiology, Texas Tech University Health Sciences Center, Lubbock, TX, - - 2014
Innovations in medical diagnosis and treatment have led to prolongation of life of patients. Increasing the life expectancy of cardiac patients and thereby increasing the prevalence of heart failure (HF). Currently more than one million hospital admissions per year are due to HF and it has been estimated that the ...
Aslan Eyup - - 2014
Cardiac rhabdomyoma, the primary cardiac tumor most often diagnosed in children, is frequently present in patients with tuberous sclerosis. Most pediatric patients with rhabdomyoma are asymptomatic; however, various electrocardiographic abnormalities can be detected, such as Wolff-Parkinson-White syndrome, ectopic atrial tachycardia, and atrioventricular node dysfunction. We describe the case of a ...
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