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Sajeev Chakanalil Govindan CG Department of Cardiology, Government Medical College, Kozhikode, Kerala, - - 2014
We report a case of young male referred for evaluation of recent onset recurrent syncope. Inhospital electrocardiogram revealed an episode of ventricular flutter which reverted spontaneously to sinus rhythm. Transthoracic echocardiogram showed hyperechoic mass in the left ventricle. For further tissue characterization a cardiac magnetic resonance imaging was done which ...
Unsöld Bernhard B Department of Cardiology and Pulmonary Medicine, University Medical Center of the Georg August University Goettingen, - - 2014
Elevated insulin and inflammatory cytokine levels in obesity may chronically activate signaling pathways regulating cardiac growth and contractility. Our aim was to examine the effect of obesity on cardiac PI3K isoform and Akt activation during left ventricular (LV) hypertrophy and heart failure. Wildtype mice were fed normal chow or high-fat ...
Gomes da Silva Ananília Medeiros AM Department of Clinical and Toxicologic Analyses, Federal University of Rio Grande do Norte , Natal, RN , - - 2014
Abstract Atrial fibrillation (AF) is a highly prevalent arrhythmia with pronounced morbidity and mortality. Genetics analysis has established electrophysiological substrates, which determine individual vulnerability to AF occurrence and maintenance. MicroRNAs (miRNAs) found in virtually all organisms function as negative regulators of protein-coding genes. Several studies have suggested a role for ...
Wilson Christopher M CM Department of Zoology, University of British Columbia, Vancouver, British Columbia, V6T 1Z4, Canada. Electronic address: - - 2014
In order for an animal to survive, the heart beat must go on in all environmental conditions, or at least restart its beat. This review is about maintaining a rhythmic heartbeat under the extreme conditions of anoxia (or very severe hypoxia) and high temperatures. It starts by considering the primitive ...
Vukajlovic Dejan D Institute for Cardiovascular Diseases Dedinje, Belgrade, - - 2014
In this study, we sought to determine whether myocardial contractile reserve (CR) assessed by dobutamine stress echocardiography (DSE) can identify patients who experience nearly complete normalization of left ventricular (LV) function after the implantation of a cardiac resynchronization therapy (CRT) pacemaker. The study group consisted of 55 consecutive patients with ...
Kim Tae-Hun - - 2014
A rebuttal to Chun KJ, Lee SG, Son BS, Kim Do H: Life-threatening cardiac tamponade: a rare complication of acupuncture. J Cardiothorac Surg 2014, 9:61.
Cho Jung Rae JR University of Florida College of Medicine-Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, - - 2014
Atrial fibrillation (AF) represents the most common cardiac arrhythmia and chronic oral anticoagulation (OAC) is the cornerstone therapy to prevent cerebrovascular events among those having high thromboembolic risk. However, 20-30% of patients with AF have co-existing coronary artery disease (CAD). Importantly, since the prevalence of both AF and CAD increase ...
Baek Seol-Hee SH Department of Neurology, Korea University College of Medicine, Seoul, Republic of - - 2014
Ischemic stroke is the most common neurologic manifestation of cardiac myxoma. However, there has been no current guideline on the treatment of hyperacute ischemic stroke due to cardiac myxoma. We describe a patient with hyperacute stroke caused by cardiac myxoma who had a good outcome with rapid recanalization through mechanical ...
John Seby S Cerebrovascular Center, Cleveland Clinic, OH, - - 2014
Systemic vascular alterations have not been described in reversible cerebral vasoconstriction syndrome (RCVS). We present a case series of RCVS patients having cardiac dysfunction during ictus, with a subset showing complete resolution of cardiomyopathy. Retrospective case-series: Cardiac left ventricular ejection fraction (LVEF) and wall motion abnormalities (WMA) visualized on transthoracic ...
Li Ji-Ke JK Cardiovascular Center of Hainan Medical College, Affiliated Hospital of Hainan Medical College, Haikou, - - 2014
The management of cardiac arrest after cardiac surgery differs from the management of cardiac arrest under other circumstances. In other studies, interposed abdominal compression-cardiopulmonary resuscitation (IAC-CPR) resulted in a better outcome compared with conventional CPR. The aim of the present study was to determine the feasibility, safety and efficacy of ...
Goodacre Steve S School of Health and Related Research (ScHARR), University of Sheffield, Regent Court, Regent Street, Sheffield, S1 4DA, United Kingdom. Electronic address: - - 2014
Suspected myocardial infarction (MI) is a common reason for emergency hospital attendance and admission. Cardiac biomarker measurement is an essential element of diagnostic assessment of suspected MI. Although the cost of a routinely available biomarker may be small, the large patient population and consequences in terms of hospital admission and ...
Papanikolaou John - - 2014
Subarachnoid hemorrhage may be complicated by neurogenic stunned myocardium, a catecholamine-induced transient cardiomyopathy that displays a wide clinical spectrum of cardiac abnormalities, including electrocardiographic changes, arrhythmias, myocardial necrosis, and left ventricular systolic and diastolic dysfunction. However, less is known about the cardiac metabolic consequences of acute subarachnoid hemorrhage. Prunet and ...
Lee Ki Hong KH Chonnam National University Hospital, Gwangju, South - - 2014
Mechanical dyssynchrony (MD) is associated with poor outcomes in many different populations. However, the predictors for the development of MD after chronic right ventricular (RV) pacing are not well known. Pacing QRS morphology and MD using echocardiography was analyzed in 175 consecutive patients that have pacemaker implantation during a 7.6year ...
Harada Masahide M Department of Cardiovascular Research, Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan, - - 2014
Midkine (MK), a heparin-binding growth factor, has been shown to prevent cardiac remodeling after ischemic injury through its anti-apoptotic effect. Cell apoptosis is central to the pathophysiology of cardiac remodeling in congestive heart failure (CHF) of ischemic as well as non-ischemic origin. We hypothesized that MK exerts the anti-apoptotic cardioprotective ...
McKeever Rita G RG Department of Emergency Medicine, Drexel University College of Medicine, Philadelphia, PA, USA, - - 2014
The adverse effects of synthetic cannabinoids are not well-described nor have they been thoroughly studied. A 16-year-old male with a past medical history of asthma and attention deficit hyperactivity disorder (ADHD) presented to the emergency department (ED) complaining of 24 h of substernal pressure associated with dyspnea, nausea, and vomiting. He ...
Harris Tim T aEmergency Medicine, Barts Health NHS Trust bEmergency Medicine, London Emergency Academic Research Network (LEARN) cLondon Emergency Academic Research Network (LEARN) dEmergency Medicine, London's Air Ambulance eEmergency Medicine, East Anglia Air Ambulance fEmergency Medicine and Pre-Hospital Care, Oxford University Hospitals gEmergency Medicine and Pre-Hospital Care, Thames Valley Air Ambulance hPrimary Care, Merseyside Deanery iEmergency Medicine and Trauma, King's College Hospital NHS Trust jKent Surrey and Sussex Air - - 2014
Resuscitation of patients who sustain a cardiac arrest as a result of trauma (traumatic cardiac arrest) has previously been described as 'futile'. Several published series have since contradicted this claim and reported survival-to-discharge data ranging from 0 to 35%. International resuscitation guidelines (European Resuscitation Council and American Heart Association) promote ...
Siasos Gerasimos - - 2014
Background: Patients with heart failure (HF) have a significant decline of renal function. We investigate the association between novel biomarkers of renal dysfunction and indices of inflammatory status and cardiac remodeling in patients with HF. Methods: We enrolled 79 consecutive patients with HF and 79 healthy subjects, adjusted for age ...
Guzzo-Merello Gonzalo G Gonzalo Guzzo-Merello, Marta Cobo-Marcos, Maria Gallego-Delgado, Pablo Garcia-Pavia, Heart Failure and Inherited Cardiac Diseases Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro, 28222 Madrid, - - 2014
Alcohol is the most frequently consumed toxic substance in the world. Low to moderate daily intake of alcohol has been shown to have beneficial effects on the cardiovascular system. In contrast, exposure to high levels of alcohol for a long period could lead to progressive cardiac dysfunction and heart failure. ...
Zhang Li L Li Zhang, Obinna Mmagu, Peter R Kowey, Center for Clinical Cardiology, Lankenau Institute for Medical Research, Lankenau Medical Center, Jefferson Medical College, Philadelphia, PA 19096, United - - 2014
Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death (SCD) in the young, particularly among athletes. Identifying high risk individuals is very important for SCD prevention. The purpose of this review is to stress that noninvasive diagnostic testing is important for risk assessment. Extreme left ventricular hypertrophy ...
Yin Jie J Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Ji'nan, Shandong, China; Department of Cardiology School of Medicine, Shandong University, Ji'nan, Shandong, - - 2014
Cardiac resynchronization therapy (CRT) is a well-established therapy for patients with heart failure (HF) and wide QRS configuration, especially for those in sinus rhythm. However, for those with permanent AF, atrioventricular nodal (AVN) ablation use remains under debate. Our objective was to evaluate clinical outcomes and mortality of AVN ablation ...
Kanmanthareddy Arun - - 2014
Atrial fibrillation occurring in the absence of cardiovascular disease in individuals younger than 60 years is known as lone atrial fibrillation. Nearly 1-12% of atrial fibrillation is considered to be lone atrial fibrillation. As our understanding of atrial fibrillation grows, we wonder as to whether there is such as thing ...
Dres Martin M aService de réanimation médicale, Hôpital de Bicêtre, Hôpitaux universitaires, Assistance Publique - Hôpitaux de Paris bEA4533, Université Paris-Sud, Le Kremlin-Bicêtre, Paris, - - 2014
Because of heart-lung interactions, weaning from mechanical ventilation induces strong hemodynamic changes that can lead to weaning-induced cardiac failure. Cardiac patients are particularly at risk for this complication. In this review, we will summarize the most recent advances concerning the mechanisms, diagnosis and treatment of weaning-induced cardiac failure. The role ...
Cullen Michael W MW Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address: - - 2014
Transesophageal echocardiography (TEE) is often performed during cardiac operations. The need to repeat TEE to exclude left atrial or left atrial appendage thrombus before direct current cardioversion (DCCV) in patients with a recent intraoperative TEE showing no thrombus is unclear. We sought to determine the incidence of and risk factors ...
Livneh Amit A Department of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, 32000, Israel. Electronic address: - - 2014
Ultrasound has been shown to produce Premature Ventricular Contractions (PVC's). Two clinical applications in which acute cardiac pacing by ultrasound may be valuable are: (1) preoperative patient screening in cardiac resynchronization therapy surgery; (2) Emergency life support, following an event of sudden death, caused by cardiac arrest. Yet, previously the ...
Gowd B M P BM Cardiology, Hartford Hospital, Hartford, United - - 2014
Myocardial bridging, which is defined as cardiac muscle overlying a part of a coronary artery, is the most common congenital coronary artery anomaly. Myocardial bridging is usually benign, but has been associated with exercise-related cardiac events. Guidelines for athletic participation in these patients are primarily based on reports from the ...
Zhao Jun J Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, People's Republic of - - 2014
To investigate the effects of the angiotensin-(1-7) signaling pathway and the possible role of atrial natriuretic peptide (ANP) on atrial electrical remodeling in canines with acute atrial tachycardia. Forty dogs were randomly assigned to eight groups (five dogs/group): sham, paced control, paced + angiotensin-(1-7), paced + angiotensin-(1-7) + Mas inhibitor, ...
Bogossian Harilaos H Märkische Kliniken GmbH, Department of Cardiology and Angiology, Klinikum Lüdenscheid, Germany; Department of Cardiology, University Witten / Herdecke, Germany. Electronic address: - - 2014
Left-bundle-branch-block(LBBB) and QT-prolongation are both associated with a worse prognosis. LBBB lengthens the QT-interval. So far it is not known if QT-time prolongation during LBBB differs in repolarization from QT-time prolongation during narrow QRS. The aim of the present proof-of-concept-study is therefore to develop a formula that allows to compare ...
Smith Ryan S RS Department of Anesthesia, McMaster University, Hamilton; Department of Anesthesiology and Perioperative Medicine, Schulich School of Medicine, University of Western Ontario, London, Ontario, - - 2014
Cardiac surgery and cardiopulmonary bypass are associated with release of inflammatory mediators and microcirculatory alterations that result in organ dysfunction. Near-infrared spectroscopic measurement of tissue oxygen saturation (StO2) and the vascular occlusion test (VOT) were utilized in a study of elective cardiac surgical patients as a novel, noninvasive method of ...
Westhall Erik - - 2014
Electroencephalography (EEG) is widely used to assess neurological prognosis in patients who are comatose after cardiac arrest, but its value is limited by varying definitions of pathological patterns and by inter-rater variability. The American Clinical Neurophysiology Society (ACNS) has recently proposed a standardized EEG-terminology for critical care to address these ...
Cha Y S YS Department of Emergency Medicine, Wonju College of Medicine, Yonsei University , Wonju , Republic of - - 2014
Background. In organophosphate (OP) poisoning cardiac complications may occur. However, the current body of knowledge largely consists of limited studies, and case reports are mainly on electrocardiogram (ECG) abnormalities. As definite myocardial injury is difficult to assess through ECG, we investigated the prevalence of myocardial injury through cardiac biochemical markers ...
Carvajal Karla K Laboratorio de Nutrición Experimental, Instituto Nacional de Pediatría, Mexico City, - - 2014
Obesity and insulin resistance (IR) are strongly connected to the development of subclinical cardiac dysfunction and eventually can lead to heart failure, which is the main cause of morbidity and death in patients having these metabolic diseases. It has been considered that excessive fat tissue may play a critical role ...
Madamanchi Chaitanya C Department of Medicine, University of North Carolina at Chapel Hill, NC, - - 2014
Many advances have been made in the diagnosis and management of heart failure (HF) in recent years. Cardiac biomarkers are an essential tool for clinicians: point of care B-type natriuretic peptide (BNP) and its N-terminal counterpart (NT-proBNP) levels help distinguish cardiac from non-cardiac causes of dyspnea and are also useful ...
Louwe M C MC Dept. General Internal Medicine, Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The - - 2014
Toll-like receptor-4 (TLR4), a receptor of the innate immune system, is suggested to have detrimental effects on cardiac function after myocardial infarction (MI). RP105 (CD180) is a TLR4 homolog lacking the intracellular signaling domain that competitively inhibits TLR4-signaling. Thus, we hypothesized that RP105 deficiency, by amplifying TLR4 signaling, would lead ...
Lee Ying-Hsiang YH Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA; Cardiovascular Medicine, Mackay Memorial Hospital, Taipei, - - 2014
First-degree atrioventricular (AV) block in relation to the outcome of cardiac resynchronization therapy (CRT) has not been well examined. Patients who received a CRT defibrillator or pacemaker between January 2002 and September 2010 at Mayo Clinic were classified into 2 groups: normal PR interval and prolonged PR interval. Standard sensed ...
Salas-Boni Rebeca R Department of Physiological Nursing, University of California, San Francisco, CA, USA. Electronic address: - - 2014
Over the past few years, reducing the number of false positive cardiac monitor alarms (FA) in the intensive care unit (ICU) has become an issue of the utmost importance. In our work, we developed a robust methodology that, without the need for additional non-ECG waveforms, suppresses false positive ventricular tachycardia ...
Littmann Laszlo L Department of Internal Medicine, Carolinas Medical Center, Charlotte, NC, USA. Electronic address: - - 2014
An 83-year-old woman with chronic left bundle branch block and remote history of pacemaker implantation for intermittent AV block was hospitalized for fatigue and leg swelling. She had no cardiac complaints. Routine 12-lead electrocardiogram showed sinus rhythm with left bundle branch block. There were diffuse negative T waves in the ...
Wang Jiayu J Department of Cardiac Electrophysiology, People's Hospital, Peking University, Beijing 100044, - - 2014
Cardiac resynchronization therapy (CRT) on patients with advanced and refractory heart failure has made remarkable progress. Clinically, notched QRS (nQRS) is commonly seen on electrocardiographs (ECGs) with bundle branch block morphology and on paced ECGs after implantation of a CRT device, which may reflect the heterogeneity of ventricular myocardial depolarization ...
Fender Erin A EA The Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, - - 2014
There is an increased risk of sudden cardiac death (SCD) and sudden cardiac arrest (SCA), in African Americans, the basis of which is likely multifactorial. African Americans have higher rates of traditional cardiac risk factors including hypertension, left ventricular hypertrophy, diabetes, coronary heart disease, and heart failure. There are also ...
Zogbi Camila C Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, - - 2014
One-day-old mice display a brief capacity for heart regeneration after apex resection. We sought to examine this response in a different model and to determine the impact of this early process on long-term tissue perfusion and overall cardiac function in response to stress. Apical resection of postnatal rats at day ...
Slagsvold Katrine Hordnes KH K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway Department of Cardiothoracic Surgery, St. Olav's Hospital, Trondheim University Hospital, Trondheim, - - 2014
Several of the cellular alterations involved in atrial fibrillation (AF) may be linked to mitochondrial function and altered microRNA (miR) expression. A majority of studies on human myocardium involve right atrial (RA) tissue only. There are indications that AF may affect the two atria differentially. This study aimed to compare ...
Kim Chul C Department of Rehabilitation Medicine, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, - - 2014
The dilated cardiomyopathy is the common type of cardiomyopathy, and its distinctive characteristic is the systolic dysfunction. Not many reports were issued about the efficacy of cardiac rehabilitation in patients with an advanced dilated cardiomyopathy until yet. A 50-year-old man who was diagnosed with dilated cardiomyopathy with congestive heart failure ...
Gawlik Radoslaw R Department and Clinic of Internal Diseases, Allergy and Clinical Immunology, Silesian University, School of Medicine, Zabrze, Poland. Head of Department: Prof. Barbara Rogala MD, - - 2014
We report a case of a 56-year-old woman with loss of conscious transferred to the cardiology unit where non-ST-elevation myocardial infarction was diagnosed. The patient reported a wasp sting a few minutes before the accident. The cardiac troponin level was high and confirmed damage of the heart muscle. Finally, echocardiography ...
Ullah M M Dr Mohammad Ullah, Assistant Professor, Cardiology, National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, - - 2014
Left Ventricular (LV) noncompaction is a rare disorder of endomyocardial morphogenesis. It has got a high mortality rate. It is frequently missed during diagnosis because of lack of suspicion and lack of definite diagnostic criteria. We are reporting a case of LV noncompaction in a Bangladeshi patient. Patient presented to ...
Roberts William C WC Departments of Internal Medicine (Division of Cardiology) (WCR, SAH), Pathology (WCR), and Cardiothoracic Surgery (JEC), and the Baylor Heart and Vascular Institute (WCR, CCR, JMK), Baylor University Medical Center, Dallas, Texas. Carey Camille Roberts is currently a freshman at Georgetown University School of Medicine, Washington, - - 2014
Cardiac transplantation (CT) has been one of the great medical advances of the last nearly 50 years. We studied the explanted hearts of 314 patients having CT at Baylor University Medical Center Dallas from 1993 to 2012, and compared the morphologic diagnoses to the clinical diagnoses before CT. Among the ...
B Amirtha Ganesh AG Professor, Department of Cardiology, Mahatma Gandhi Medical College and Research Institute , Pondicherry, India - - 2014
Left Atrial Thrombus is uncommon in neonates. We present a neonate who had Paroxysmal Supraventricular Tachycardia (PSVT), whose echocardiography revealed a large left atrial thrombus which resolved later with treatment. Supra Ventricular Tachycardia (SVT) is not an uncommon event in infants with an incidence of 1:2500.
Wagner Bradley J BJ Bradley J. Wagner, PharmD, BCPS, is a board-certified pharmacotherapy specialist. He is currently completing his internal medicine pharmacy residency at Virginia Commonwealth University Health System and postresidency will remain at Virginia Commonwealth University to practice as an internal medicine pharmacy specialist. Nancy S. Yunker, BS (Pharmacy), PharmD, FCCP, BCPS, is a boardcertified pharmacotherapy specialist. She is currently Assistant Professor of Pharmacy and Nursing at the Virginia Commonwealth University (VCU). Nancy currently practices as an internal medicine pharmacy specialist at the VCU Health System but previously practiced as a general surgery pharmacy specialist at - - 2014
Cardiac arrest is manifested by arrhythmias (ventricular fibrillation or pulseless ventricular tachycardia, pulseless electrical activity, or asystole) resulting in minimal to no forward blood flow to the body's oxygen-dependent tissues. Defibrillation and cardiopulmonary resuscitation (CPR) should be initiated immediately as they have been shown to increase return of spontaneous circulation ...
Bonny A A Teaching Hospital Laquintinie, University of Douala, Douala, Cameroon; Service de Cardiologie, Centre Hospitalier Victor Provo, Roubaix, France. - - 2014
The estimated rate of sudden cardiac death (SCD) in Western countries ranges from 300 000 to 400 000 annually, which represents 0.36 to 1.28 per 1 000 inhabitants in Europe and the United States. The burden of SCD in Africa is unknown. Our aim is to assess the epidemiology of ...
Chayanupatkul Maneerat M Department of Medicine, Einstein Medical Center, Philadelphia, PA, - - 2014
Cirrhotic cardiomyopathy is a cardiac condition observed in patients with cirrhotic regardless of the etiologies. It is characterized by the impaired systolic response to physical stress, diastolic dysfunction, and electrophysiological abnormalities, especially QT interval prolongation. Its pathophysiology and clinical significance has been a focus of various researchers for the past ...
Lang Ninian N NN Scottish Advanced Heart Failure Service, Golden Jubilee National Hospital, Agamemnon Street, Clydebank, Glasgow, G81 4DY, - - 2014
Effective cardiac resynchronization therapy may depend upon the distance between left ventricular (LV) and right ventricular (RV) pacing leads. We assessed the influence of lead separation upon circulating NT-proBNP. In total, 132 patients underwent assessment, including NT-proBNP assay, before and after cardiac resynchronization therapy. 3D lead separation was calculated from ...
Gamble James Hp JH Oxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, OX3 9DU, - - 2014
Cardiac resynchronization therapy is an effective treatment for selected patients with heart failure and left bundle branch block dyssynchrony. Unfortunately, about a third of patients, so-called nonresponders, do not display any symptomatic or structural improvements after the treatment. In another 5% of patients, the left ventricular lead cannot be implanted ...
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